Whitening composition and preparation method therefor

Abstract

A whitening composition, comprising the following components in percentage by weight: 2.0% to 20.0% of an (animal) umbilical cord extract, 1.0% to 20.0% of a Cynara scolymus folium extract, and 5.0% to 10.0% of an Alpiniae katsumadai semen extract, with the balance being basic components. The basic components comprise a skin moisturizer, a thickener, a skin penetrant, a preservative and water. A method for preparing a whitening composition, the method comprising: dispersing a thickener in a skin moisturizer, and placing the resulting mixture into a production emulsifying kettle; then adding water and a skin penetrant, and heating the resulting mixture to 80-85°C to completely dissolve the mixture; reducing the temperature to 45°C or lower, sequentially adding an (animal) umbilical cord extract, a Cynara scolymus folium extract, an Alpiniae katsumadai semen extract and a preservative, then uniformly stirring the resulting mixture, and cooling the mixture to obtain a whitening composition.

Description

A whitening composition and preparation method thereof Technical Field

[0001] The present application relates to the technical field of skin care products, and in particular to a whitening composition and a preparation method thereof. Background Art

[0002] With the development of society and the improvement of people's living standards, more and more consumers are using cosmetics. According to incomplete statistics, the Chinese cosmetics market will reach 320 billion RMB in 2022. Among the vast user population, there is a user group with a large demand for whitening skin care products. Whitening is an important reason for using ordinary cosmetics.

[0003] However, existing whitening skincare products have a relatively simple mechanism of action. Some products achieve whitening effects by promoting melanin excretion, but fail to address melanin production and deposition, resulting in limited whitening results. Therefore, there is a growing demand for whitening products that can coordinately reduce melanin production, promote melanin excretion, and reduce melanin deposition. Summary of the Invention

[0004] The present invention provides a whitening composition and a preparation method thereof to solve the problems existing in the related art. The technical solution is as follows:

[0005] In a first aspect, the present invention provides a whitening composition comprising the following components by weight:

[0006] (Animal) umbilical cord extract 2.0%~20.0%

[0007] Artichoke leaf extract 1.0%-20.0%

[0008] Alpinia officinalis seed extract 5.0%~10.0%

[0009] Basic component balance.

[0010] In one embodiment, the base components include a skin moisturizer, a thickener, a skin penetrant, a preservative, and water.

[0011] In one embodiment, the following components are included by weight percentage:

[0012] (Animal) umbilical cord extract 2.0%~20.0%

[0013] Artichoke leaf extract 1.0%-20.0%

[0014] Alpinia officinalis seed extract 5.0%~10.0%

[0015] Skin moisturizer 10.0%~30.0%

[0016] Thickener 0.05%~0.5%

[0017] Skin penetrant 1.0%~5.0%

[0018] Preservatives 0.2% to 0.6%

[0019] Water balance.

[0020] In one embodiment, the skin moisturizer is a polyol.

[0021] In one embodiment, the thickening agent is carbomer;

[0022] The skin penetrant is betaine.

[0023] In one embodiment, the preservative is phenoxyethanol.

[0024] In one embodiment, the method for preparing the (animal) umbilical cord extract comprises:

[0025] Take the pig placenta, put it in a clean plastic box, seal it with ice packs, and return it to a 100,000-grade cleanliness laboratory within 12 hours. Then, wash the surface 2-3 times with physiological saline in an ultra-clean workbench.

[0026] Use scissors to cut off 1-2 cm of the umbilical cord end and discard it. Cut the remaining placental tissue into small pieces of 1-3 mm² and place them in a box with a lid. Then add tissue digestion solution in a 1:1 weight ratio of placental tissue to tissue digestion solution. Gently shake to allow all placental tissue to be immersed in the digestion solution. Then place it in a constant temperature oven at 37°C and wait for 1.5-2 hours;

[0027] Filter the soaked placenta tissue through 200-mesh clean gauze, take filtrate I, pour the filter residue back into the box, pour in normal saline in a ratio of 1:1 by weight of the filter residue to normal saline, shake well, and filter again through 200-mesh gauze to remove the filter residue. Take filtrate II, combine filtrate II and filtrate I, and then place them in a filtration device with rapid filter paper for filtration. The obtained filtrate is the (animal) umbilical cord extract.

[0028] In one embodiment, the method for preparing the artichoke leaf extract comprises:

[0029] First, wash the fresh artichoke leaves, dry them, and then dry them. Then, weigh the dried artichoke leaves, 1.3-butanediol, and 95% alcohol in a weight ratio of 1:1:1.

[0030] Place artichoke leaves, 1,3-butanediol, and 95% alcohol in a reflux pot, turn on the heat, set the heating temperature to 92°C ± 2°C, and reflux for 2 hours. After the heating and cooking is completed, cool to room temperature.

[0031] The filtrate was filtered and placed in a rotary evaporator, vacuumed, heated to 72°C±2°C, and heated for distillation. After the filtrate was evaporated until no evaporated liquid flowed out, the filtrate was mixed again with 1,3-butanediol and water in a weight ratio of 1:1:1. After mixing, the mixture was filtered through an 800-mesh filter cloth to obtain a filtrate, which is the artichoke leaf extract.

[0032] In one embodiment, the preparation method of the Alpinia fasciata seed extract comprises:

[0033] Wash the cardamom seeds, dry them, and then crush them. Weigh the crushed cardamom seeds, dipropylene glycol, and 95% alcohol in a weight ratio of 1:1:1.

[0034] Place cardamom seeds, dipropylene glycol, and 95% alcohol in a reflux pot, turn on the heat, set the heating temperature to 95°C ± 2°C, and reflux for 2 hours. After the heating and cooking is completed, cool to room temperature;

[0035] The filtrate is filtered and placed in a rotary evaporator, vacuumed, heated to 72°C±2°C, and heated for distillation. After the filtrate is evaporated until no evaporated liquid flows out, the filtrate is mixed again with dipropylene glycol and water in a weight ratio of 1:1:1. After mixing, the mixture is filtered through an 800-mesh filter cloth to obtain a filtrate, which is the cardamom seed extract.

[0036] In a second aspect, the present invention provides a method for preparing a whitening composition, comprising:

[0037] Disperse the thickener in the skin moisturizer and put it into the production emulsifier, then add water and skin penetrant, heat to 80-85°C, and dissolve the mixture completely;

[0038] The temperature is lowered to below 45°C, and the (animal) umbilical cord extract, artichoke leaf extract, cardamom seed extract and preservative are added in sequence, and then stirred evenly and cooled to obtain a whitening composition.

[0039] The advantages or beneficial effects of the above technical solution include at least:

[0040] (1) Add (animal) umbilical cord extract. (Animal) umbilical cord extract is rich in various nutrients, such as various amino acids, small molecule peptides, growth factors, etc. The umbilical cord extract extracted from pig placenta is rich in glutathione and nonapeptide-1. When used in essence, it can achieve the effect of whitening and brightening the skin.

[0041] (2) Adding artichoke leaf extract, wherein the artichoke leaf extract extracted by the method of the present application is rich in cynarin, which can inhibit NF-k, a key factor causing skin aging, and prevent skin melanin deposition and skin photoaging, thereby achieving the effect of brightening the skin.

[0042] (3) Adding cardamom seed extract, wherein the cardamom seed extract extracted by the method of the present application is rich in galangin, cardamom and eucalyptol. The eucalyptol and galangin can activate the melanin factor PLD1 of the skin, promote the excretion of melanin in the skin, reduce the melanin in the skin, and thus achieve a whitening effect.

[0043] (4) (Animal) umbilical cord extract, cardoon leaf extract, and cardamom seed extract are combined to form a whitening effect composition, which can greatly improve the whitening effect. (Animal) umbilical cord extract is rich in small molecule peptides. The nonapeptide-1 in it competes with melanocytes for receptors on melanocyte stem cells when it enters the skin, weakens the activity of melanocyte stem cells, and reduces the amount of melanin produced, thereby achieving the effect of whitening the skin. Cardamom seed extract is rich in galangin and eucalyptol. When it enters the skin, it activates the skin's melanin factor PLD1, which can greatly promote the discharge of melanin from the skin, thereby achieving the effect of whitening. Cardoon leaf extract is rich in cynarin. When it enters the skin, it can effectively inhibit the key factor NF-k of skin aging. After the key factor NF-K that causes skin aging in the skin is inhibited, the skin The melanin in the skin cannot be precipitated, and the skin can achieve good whitening. The combined effect of these three extracts is complementary, and the principles of whitening are different. They all have good effects on the production, inhibition and reduction of melanin. If only one of the extracts is used, it will not have a rapid whitening effect. Therefore, the whitening composition of the present application can not only inhibit the production of melanin from the source, but also achieve whitening effect in the skin that has already produced melanin. Therefore, the combination of these three extracts can quickly and obviously see the whitening effect, and the action time is long-lasting, which is more than 50% higher than the whitening effect of using a single extract. Therefore, the creativity of this application lies in the combined use of these three to achieve innovative whitening effects from the source to the surface of dark skin.

[0044] The above summary is for illustrative purposes only and is not intended to be limiting in any way. In addition to the illustrative aspects, embodiments and features described above, further aspects, embodiments and features of the present application will be readily apparent by reference to the following detailed description. Implementation Method

[0045] Hereinafter, only certain exemplary embodiments are briefly described. As will be appreciated by those skilled in the art, the described embodiments may be modified in various ways without departing from the spirit or scope of the present application. Therefore, the description is considered to be illustrative and non-restrictive in nature.

[0046] In order to make it more convenient for people who need whitening to use it and increase the whitening effect on the skin, the present application provides a whitening composition that is simple in formula, easy to prepare, safe and non-irritating.

[0047] The present invention provides a whitening composition comprising the following components by weight:

[0048] (Animal) umbilical cord extract 2.0%~20.0%

[0049] Artichoke leaf extract 1.0%-20.0%

[0050] Alpinia officinalis seed extract 5.0%~10.0%

[0051] Basic component balance.

[0052] In one embodiment, the base components include a skin moisturizer, a thickener, a skin penetrant, and water.

[0053] In one embodiment, the base component further comprises a preservative.

[0054] In one embodiment, the following components are included by weight percentage:

[0055] (Animal) umbilical cord extract 2.0%~20.0%

[0056] Artichoke leaf extract 1.0%-20.0%

[0057] Alpinia officinalis seed extract 5.0%~10.0%

[0058] Skin moisturizer 10.0%~30.0%

[0059] Thickener 0.05%~0.5%

[0060] Skin penetrant 1.0%~5.0%

[0061] Preservatives 0.2% to 0.6%

[0062] Water balance.

[0063] In one embodiment, the skin moisturizer is a polyol. Adding the polyol as a skin moisturizer can better help the whitening composition penetrate into the basal layer of the skin.

[0064] In one embodiment, the thickener is carbomer. Carbomer is added as a thickener to better use the whitening essence.

[0065] In one embodiment, the skin penetrant is betaine. Adding betaine as a skin penetrant allows the active ingredients in the formula to penetrate into the skin, while also balancing the osmotic pressure of cells, thus achieving multiple benefits.

[0066] In one embodiment, the preservative is phenoxyethanol.

[0067] In one embodiment, a method for preparing an umbilical cord extract of an animal comprises:

[0068] Take the pig placenta, put it in a clean plastic box, seal it with ice packs, and return it to a 100,000-grade cleanliness laboratory within 12 hours. Then, wash the surface 2-3 times with physiological saline in an ultra-clean workbench.

[0069] Use scissors to cut off 1-2 cm of the umbilical cord end and discard it. Cut the remaining placental tissue into small pieces of 1-3 mm² and place them in a box with a lid. Then add tissue digestion solution in a 1:1 weight ratio of placental tissue to tissue digestion solution. Gently shake to allow all placental tissue to be immersed in the digestion solution. Then place it in a constant temperature oven at 37°C and wait for 1.5-2 hours;

[0070] Filter the soaked placenta tissue through 200-mesh clean gauze, take filtrate I, pour the filter residue back into the box, pour in normal saline in a ratio of 1:1 by weight of the filter residue to normal saline, shake well, and filter again through 200-mesh gauze to remove the filter residue. Take filtrate II, combine filtrate II and filtrate I, and then place them in a filtration device with rapid filter paper for filtration. The obtained filtrate is the (animal) umbilical cord extract.

[0071] In one embodiment, a method for preparing an artichoke leaf extract comprises:

[0072] First, wash the fresh artichoke leaves, dry them, and then dry them. Then, weigh the dried artichoke leaves, 1.3-butanediol, and 95% alcohol in a weight ratio of 1:1:1.

[0073] Place artichoke leaves, 1,3-butanediol, and 95% alcohol in a reflux pot, turn on the heat, set the heating temperature to 92°C ± 2°C, and reflux for 2 hours. After the heating and cooking is completed, cool to room temperature.

[0074] The filtrate was filtered and placed in a rotary evaporator, vacuumed, heated to 72°C±2°C, and heated for distillation. After the filtrate was evaporated until no evaporated liquid flowed out, the filtrate was mixed again with 1,3-butanediol and water in a weight ratio of 1:1:1. After mixing, the mixture was filtered through an 800-mesh filter cloth to obtain a filtrate, which is the artichoke leaf extract.

[0075] In one embodiment, the preparation method of Alpinia fasciata seed extract comprises:

[0076] Wash the cardamom seeds, dry them, and then crush them. Weigh the crushed cardamom seeds, dipropylene glycol, and 95% alcohol in a weight ratio of 1:1:1.

[0077] Place cardamom seeds, dipropylene glycol, and 95% alcohol in a reflux pot, turn on the heat, set the heating temperature to 95°C ± 2°C, and reflux for 2 hours. After the heating and cooking is completed, cool to room temperature;

[0078] The filtrate is filtered and placed in a rotary evaporator, vacuumed, heated to 72°C±2°C, and heated for distillation. After the filtrate is evaporated until no evaporated liquid flows out, the filtrate is mixed again with dipropylene glycol and water in a weight ratio of 1:1:1. After mixing, the mixture is filtered through an 800-mesh filter cloth to obtain a filtrate, which is the cardamom seed extract.

[0079] Example 1

[0080] A whitening composition (essence) is composed of the following components in the following weight ratios:

[0081] Water 41.7%

[0082] (Animal) umbilical cord extract 20.0%

[0083] Artichoke Leaf Extract 20.0%

[0084] Alpinia officinalis seed extract 10.0%

[0085] Glycerin 6.0%

[0086] Betaine 2.0%

[0087] Carbomer 0.3%

[0088] Phenoxyethanol 1.0%

[0089] in:

[0090] A. (Animal) umbilical cord extract is prepared by the following method:

[0091] The pig placenta collected from the farm is placed in a clean plastic box, sealed with ice packs, and returned to a 100,000-grade cleanliness laboratory within 12 hours. The surface is then washed 2-3 times with saline in an ultra-clean bench to remove as much blood stains as possible.

[0092] Use scissors to cut off 1-2 cm of the umbilical cord end and discard it. Cut the remaining placental tissue into small pieces of 1-3 mm² and place them in a covered box. Then add tissue digestion solution at a weight ratio of 1:1. After adding, gently shake to allow all the placental tissue to be immersed in the digestion solution. Then place it in an oven at a constant temperature of 37°C and wait for 1.5-2 hours. The tissue digestion solution was purchased from Fuyuan (Shanghai) Biotechnology Co., Ltd., and the product number is RC200104.

[0093] Then filter with 200-mesh clean gauze, take filtrate I, pour the filter residue back into the box, pour in normal saline in a ratio of 1:1 by weight of the filter residue and normal saline, shake well, and filter again with the 200-mesh gauze just used, remove the filter residue, take filtrate II and combine it with the filtrate I filtered in the first step, and then place it in a filtration device with rapid filter paper for filtration. The obtained filtrate is the (animal) umbilical cord extract.

[0094] B. Artichoke leaf extract was prepared by the following method:

[0095] First, wash the fresh artichoke leaves, dry them, and then dry them. Then, weigh the dried artichoke leaves, 1.3-butanediol, and 95% alcohol in a weight ratio of 1:1:1.

[0096] Place artichoke leaves, 1,3-butanediol, and 95% alcohol in a reflux pot, turn on the heat, set the heating temperature to 92°C ± 2°C, and reflux for 2 hours. After the heating and cooking is completed, cool to room temperature.

[0097] The filtrate was filtered and placed in a rotary evaporator, vacuumed, heated to 72°C±2°C, and heated for distillation. After the filtrate was evaporated until no evaporated liquid flowed out, the filtrate was mixed again with 1,3-butanediol and water in a weight ratio of 1:1:1. After mixing, the mixture was filtered through an 800-mesh filter cloth to obtain a filtrate, which is the artichoke leaf extract.

[0098] C. Alpinia officinalis seed extract was prepared by the following method:

[0099] First, wash the cardamom seeds, dry them, and then crush them. Weigh the crushed cardamom seeds, dipropylene glycol, and 95% alcohol in a weight ratio of 1:1:1.

[0100] Place cardamom seeds, dipropylene glycol, and 95% alcohol in a reflux pot, turn on the heat, set the heating temperature to 95°C ± 2°C, and reflux for 2 hours. After the heating and cooking is completed, cool to room temperature;

[0101] The filtrate is filtered and placed in a rotary evaporator, vacuumed, heated to 72°C±2°C, and heated for distillation. After the filtrate is evaporated until no evaporated liquid flows out, the filtrate is mixed again with dipropylene glycol and water in a weight ratio of 1:1:1. After mixing, the mixture is filtered through an 800-mesh filter cloth to obtain a filtrate, which is the cardamom seed extract.

[0102] The preparation method of the whitening composition (essence) of this embodiment is as follows:

[0103] Disperse glycerin and carbomer thoroughly and add them to an emulsifier. Then add purified water and betaine. Stir and heat until the mixture reaches 82±2°C. Keep warm for 5 minutes and stir until the mixture dissolves evenly.

[0104] When the temperature drops below 45° C., add (animal) umbilical cord extract, artichoke leaf extract, cardamom seed extract, and phenoxyethanol in sequence, then stir evenly and mix thoroughly to obtain an essence containing a whitening composition.

[0105] Example 2

[0106] A whitening composition (essence) is composed of the following components in the following weight ratios:

[0107] Water 61.7%

[0108] (Animal) umbilical cord extract 10.0%

[0109] Artichoke Leaf Extract 10.0%

[0110] Alpinia officinalis seed extract 5.0%

[0111] Glycerin 6.0%

[0112] Betaine 2.0%

[0113] Carbomer 0.3%

[0114] Phenoxyethanol 1.0%.

[0115] in:

[0116] A. The preparation method of (animal) umbilical cord extract is the same as that in Example 1.

[0117] B. The preparation method of artichoke leaf extract is the same as that in Example 1.

[0118] C. The preparation method of Alpinia fasciata seed extract is the same as that in Example 1.

[0119] D. The preparation method of the essence rich in the whitening composition is the same as that in Example 1. Example 3

[0120] A whitening composition (essence) is composed of the following components in the following weight ratios:

[0121] Water 82.7%

[0122] (Animal) umbilical cord extract 2.0%

[0123] Artichoke Leaf Extract 1.0%

[0124] Alpinia officinalis seed extract 5.0%

[0125] Glycerin 6.0%

[0126] Betaine 2.0%

[0127] Carbomer 0.3%

[0128] Phenoxyethanol 1.0%.

[0129] in:

[0130] A. The preparation method of (animal) umbilical cord extract is the same as that in Example 1.

[0131] B. The preparation method of artichoke leaf extract is the same as that in Example 1.

[0132] C. The preparation method of Alpinia fasciata seed extract is the same as that in Example 1.

[0133] D. The preparation method of the essence rich in the whitening composition is the same as that in Example 1.

[0134] Comparative Example 1

[0135] A whitening composition (essence) is composed of the following components in the following weight ratios:

[0136] Water 70.7%

[0137] (Animal) umbilical cord extract 20.0%

[0138] Glycerin 6.0%

[0139] Betaine 2.0%

[0140] Carbomer 0.3%

[0141] Phenoxyethanol 1.0%.

[0142] in:

[0143] A. The preparation method of (animal) umbilical cord extract is the same as that in Example 1.

[0144] B. The preparation method of the essence rich in the whitening composition is the same as that in Example 1.

[0145] Comparative Example 2

[0146] A whitening composition (essence) is composed of the following components in the following weight ratios:

[0147] Water 80.7%

[0148] Artichoke Leaf Extract 10.0%

[0149] Glycerin 6.0%

[0150] Betaine 2.0%

[0151] Carbomer 0.3%

[0152] Phenoxyethanol 1.0%.

[0153] in:

[0154] A. The preparation method of artichoke leaf extract is the same as that in Example 1.

[0155] B. The preparation method of the essence rich in the whitening composition is the same as that in Example 1.

[0156] Comparative Example 3

[0157] A whitening composition (essence) is composed of the following components in the following weight ratios:

[0158] Water 80.7%

[0159] Alpinia officinalis seed extract 10.0%

[0160] Glycerin 6.0%

[0161] Betaine 2.0%

[0162] Carbomer 0.3%

[0163] Phenoxyethanol 1.0%.

[0164] in:

[0165] A. The preparation method of Alpinia fasciata seed extract is the same as that in Example 1.

[0166] B. The preparation method of the essence rich in the whitening composition is the same as that in Example 1.

[0167] 1. The physical and chemical stability tests were conducted on the essences rich in the whitening composition of Example 1, Example 2, Example 3, Comparative Example 1, Comparative Example 2, and Comparative Example 3. The results are as follows:

[0168] 1. Appearance: translucent yellow to slightly yellow viscous liquid

[0169] 2. pH value: 5.5.0-7.5

[0170] 3. Heat resistance stability test (48℃×48h): qualified.

[0171] 4. Cold resistance stability test (-15℃×48h): qualified.

[0172] 2. In order to prove the safety of this product, the following tests were conducted:

[0173] 1. Safety testing:

[0174] Twenty-four volunteers with good skin were randomly selected to form six groups, each consisting of four volunteers. Each group was tested with the whitening essence samples of Examples 1-3 and Comparative Examples 1-3. Each participant performed a patch control experiment on the inside of their left arm. A 36-well patch of the present invention was applied to the inside of their left arm. Skin reactions were recorded after 24, 48, and 72 hours. The data are shown in the following table:

[0175]

[0176] Experimental results: After applying the product of the present invention for 24 hours, 48 ​​hours, and 72 hours, no allergic reactions such as redness, itching, or erythema were observed, indicating that the whitening composition (essence) in the examples of the present application and the whitening composition (essence) in the comparative example are safe and do not cause any adverse reactions.

[0177] 2. Evaluation test of whitening efficacy:

[0178] Test samples: whitening composition (essence) samples of Examples 1-3 and Comparative Examples 1-3.

[0179] Testing equipment: Skin-SP skin tester equipped with a high-definition melanin probe.

[0180] Test steps:

[0181] Six volunteers with healthy skin aged 30-40 were randomly selected and numbered No. 1, No. 2, No. 3, No. 4, No. 5, and No. 6. Volunteer No. 1 used the whitening essence of Example 1, volunteer No. 2 used the whitening essence of Example 2, volunteer No. 3 used the whitening essence of Example 3, volunteer No. 4 used the whitening essence of Example 4, volunteer No. 5 used the whitening essence of Example 5, and volunteer No. 6 used the whitening essence of Example 6.

[0182] First, before using the whitening essence, 6 volunteers were tested with the Skin-SP skin tester, and the melanin data of the face before use was scanned. The 6 volunteers all chose the facial skin next to the nose clip on the left side of the face and fixed the position. Then the volunteers were asked to use the corresponding whitening essence sample in this area twice a day, after washing their face. No other whitening products could be used during the period of using the whitening essence. The same type of sunscreen must be applied when going out. The changes in skin melanin content were recorded for 7 days, 14 days, 21 days, and 28 days respectively.

[0183] The experimental data obtained are as follows:

[0184]

[0185] Experimental results: Through the above experiment, it was found that the melanin content on the face of the volunteers in Example 1 changed the most after 28 days of use, with a reduction of melanin by 78.3%. The whitening composition in Example 2 had its content halved, and the effect of removing melanin was also very obvious. Therefore, the whitening effect of the whitening composition of the present application on the skin is very obvious.

[0186] In summary, the above experiments demonstrate that the whitening composition of this application exhibits good product stability, safety, and effectiveness. As the amount of whitening combination extract added decreases, the melanin removal effect on the skin also decreases. The whitening composition of this application is a safe and highly effective skin care product that can be used as an innovative whitening cosmetic.

[0187] In the description of this specification, the reference terms "one embodiment," "some embodiments," "example," "specific example," or "some examples" mean that the specific features, structures, materials, or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present application. Moreover, the specific features, structures, materials, or characteristics described may be combined in any appropriate manner in any one or more embodiments or examples. In addition, those skilled in the art may combine and combine different embodiments or examples described in this specification, as well as features of different embodiments or examples, unless they are mutually inconsistent.

[0188] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features being referred to. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. Throughout the description of this application, "plurality" means two or more, unless otherwise specifically defined.

[0189] The above description is merely a specific embodiment of the present application, but the scope of protection of the present application is not limited thereto. Any person skilled in the art can easily conceive of various modifications or substitutions within the technical scope disclosed in this application, and such modifications or substitutions should be included within the scope of protection of the present application. Therefore, the scope of protection of the present application should be based on the scope of protection of the claims.

Claims

1. A whitening composition, characterized in that: By weight percentage, it includes the following components: (Animal) umbilical cord extract 2.0%~20.0% Artichoke leaf extract 1.0%~20.0% Alpinia fasciata seed extract 5.0%~10.0% Base component balance.

2. The whitening composition according to claim 1, characterized in that The base components include skin moisturizers, thickeners, skin penetrants, preservatives and water.

3. The whitening composition according to claim 2, characterized in that By weight percentage, it includes the following components: (Animal) umbilical cord extract 2.0%~20.0% Artichoke leaf extract 1.0%~20.0% Alpinia fasciata seed extract 5.0%~10.0% Skin moisturizer 10.0%~30.0% Thickener 0.05%~0.5% Skin penetrant 1.0%~5.0% Preservatives 0.2%~0.6% Water balance.

4. The whitening composition according to any one of claims 2 to 3, characterized in that The skin moisturizer is a polyol.

5. The whitening composition according to any one of claims 2 to 3, characterized in that: The thickener is carbomer; The skin penetrant is betaine.

6. The whitening composition according to any one of claims 2 to 3, characterized in that: The preservative is phenoxyethanol.

7. The whitening composition according to any one of claims 1 to 3, characterized in that The preparation method of the (animal) umbilical cord extract comprises: Take the pig placenta, put it in a clean plastic box, seal it with ice packs, and send it back to a 100,000-grade clean laboratory within 12 hours. Then wash the surface 2-3 times with saline in an ultra-clean workbench. Cut off 1-2cm of the umbilical cord with scissors and discard it. Cut the remaining placental tissue into small pieces of 1-3mm² and place them in a box with a lid. Add tissue digestion solution in a 1:1 weight ratio of placental tissue to tissue digestion solution, shake gently to allow all placental tissue to be immersed in the digestion solution, and then place it in a constant temperature oven at 37°C and wait for 1.5-2 hours; Use 200-mesh clean gauze to filter the soaked placenta tissue, take filtrate I, pour the filter residue back into the box, pour into normal saline in a weight ratio of 1:1 between the filter residue and normal saline, shake well, filter again with 200-mesh gauze, remove the filter residue, take filtrate II, combine filtrate II and filtrate I, and then place it in a suction filtration device with rapid filter paper for suction filtration. The obtained filtrate is the (animal) umbilical cord extract.

8. The whitening composition according to any one of claims 1 to 3, characterized in that The preparation method of the cardoon leaf extract comprises: First, wash the fresh artichoke leaves, dry them, and then dry them. Then, weigh the dried artichoke leaves, 1.3-butanediol, and 95% alcohol in a weight ratio of 1:1:

1. Put cardoon leaves, 1,3-butanediol and 95% alcohol into a reflux pot, turn on the heating, set the heating temperature to 92°C±2°C, heat and reflux for 2 hours, and cool to room temperature after the heating and cooking is completed; The filtrate is filtered and placed in a rotary evaporator, vacuumed, heated to 72°C±2°C, and heated for distillation. After the filtrate is evaporated until no evaporated liquid flows out, the filtrate is mixed with 1.3-butanediol and water in a weight ratio of 1:1:1 again, and then filtered with an 800-mesh filter cloth to obtain the filtrate, which is the artichoke leaf extract.

9. The whitening composition according to any one of claims 1 to 3, characterized in that The preparation method of the cardamom seed extract comprises: Wash the cardamom seeds, dry them, and then crush them. Weigh the crushed cardamom seeds, dipropylene glycol, and 95% alcohol in a weight ratio of 1:1:

1. Put cardamom seeds, dipropylene glycol, and 95% alcohol into a reflux pot, turn on the heating, set the heating temperature to 95°C±2°C, heat and reflux for 2 hours, and cool to room temperature after the heating and cooking is completed; Filter and take the filtrate, place the filtrate in a rotary evaporator, evacuate, heat to 72°C±2°C, start heating distillation, and after the filtrate is evaporated until no evaporated liquid flows out, mix the filtrate with dipropylene glycol and water in a weight ratio of 1:1:1 again, filter with 800-mesh filter cloth after mixing, and take the filtrate, which is the cardamom seed extract.

10. A method for preparing a whitening composition, characterized in that: include: Disperse the thickener in the skin moisturizer and put it into the production emulsifier, then add water and skin penetrant, heat to 80-85°C to dissolve the mixture completely; The temperature is lowered to below 45°C, and (animal) umbilical cord extract, cardamom leaf extract, cardamom seed extract and preservatives are added in sequence, then stirred evenly and cooled to obtain a whitening composition.

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