Tooth whitening gel and preparation method therefor

Abstract

A tooth whitening gel and a preparation method therefor, prepared using a mixed solution A and a mixed solution B in a component ratio of 1:1. The mixed solution A is composed of the following components: hydrogen peroxide, any one of potassium nitrate or sodium fluoride, any one of sodium stannate, sodium pyrophosphate or sodium silicate, and deionized water. The mixed solution B is composed of the following components: any one of a carbomer or polyacrylic acid, triethanolamine, any one of magnesium sulfate or magnesium silicate, any one of glycerol or propylene glycol, and deionized water. The tooth whitening gel can inhibit the rapid decomposition of hydrogen peroxide, forming an optimal pH range for effective decomposition of hydrogen peroxide, so that a relatively low concentration of hydrogen peroxide can still achieve a relatively good bleaching effect. This increases the viscosity of the tooth whitening gel, reduces the fluidity on the tooth surface during use, prevents damage to the gums, has an anti-allergy effect, and reduces sensitivity of the teeth caused by hydrogen peroxide.

Description

A tooth whitening gel and preparation method thereof Technical Field

[0001] The present invention relates to the technical field of tooth whitening, and in particular to a tooth whitening gel and a preparation method thereof. Background Art

[0002] With the improvement of living standards, modern people have higher and higher requirements for oral beauty, which can be specifically reflected in the increasing demand for whitening teeth. Currently, there are the following problems with the teeth whitening gels on the market:

[0003] First, its pH stability is low, and everyone's oral pH is not fixed, which leads to large differences in the whitening effect of teeth whitening gel on different people;

[0004] Secondly, its fluidity is relatively high. During use, the solution flows from the tooth surface to the gums or oral cavity, oxidizing the oral soft tissue or mucosa, increasing the pain of consumers;

[0005] Finally, the main bleaching ingredients are high-concentration hydrogen peroxide or carbamide peroxide. Hydrogen peroxide is a strong oxidant, and its bleaching effect is achieved by decomposing it into free oxygen and free radicals, which then penetrate into the teeth and react with pigment groups. However, hydrogen peroxide has the following problems:

[0006] (1) Hydrogen peroxide is relatively unstable, decomposes rapidly, and has a short shelf life;

[0007] (2) Hydrogen peroxide can only be effectively decomposed into free oxygen and free radicals under alkaline conditions, and is not easily decomposed under acidic conditions;

[0008] (3) When hydrogen peroxide encounters metal ions, it will accelerate the ineffective decomposition of hydrogen peroxide and decompose it into oxygen and water that have no bleaching effect.

[0009] Therefore, in order to overcome the above problems and achieve good whitening effects, manufacturers often choose to increase the concentration of hydrogen peroxide in whitening products. However, excessive hydrogen peroxide may cause damage to the patient's dental pulp and gum tissue.

[0010] Another major bleaching ingredient is carbamide peroxide. Compared to hydrogen peroxide, carbamide peroxide is more stable and less prone to decomposition. The bleaching mechanism of carbamide peroxide is to produce hydrogen peroxide after decomposition. However, carbamide peroxide has the following problems:

[0011] (1) 10% carbamide peroxide can only decompose into 3.6% hydrogen peroxide, so to achieve the same bleaching effect, the concentration of carbamide peroxide must be much higher than that of hydrogen peroxide;

[0012] (2) Urea peroxide decomposes into hydrogen peroxide while also generating harmful substances such as urea, carbon dioxide, and ammonia, which can produce irreversible side effects;

[0013] (3) Urea peroxide is more expensive to deliver than hydrogen peroxide.

[0014] Therefore, both bleaching agents have their own shortcomings, and the problem of low pH stability of tooth whitening products leads to poor teeth whitening effect for consumers. How to overcome the above problems is an urgent problem to be solved. Summary of the Invention

[0015] The present invention aims to overcome the problems of existing tooth whitening gels. The tooth whitening gel and its preparation method provided by the present invention inhibit the rapid decomposition of hydrogen peroxide, establishing an optimal pH range for effective hydrogen peroxide decomposition, enabling a good bleaching effect even at lower hydrogen peroxide concentrations. The gel also increases viscosity, reduces fluidity on the tooth surface during use, prevents damage to the gums, exhibits anti-allergic effects, and reduces tooth sensitivity caused by hydrogen peroxide.

[0016] In order to achieve the above object, the technical solution adopted by the present invention is:

[0017] A teeth whitening gel is prepared by mixing liquid A and liquid B in a ratio of 1:1.

[0018] Wherein, according to mass percentage, mixed solution A is composed of the following components:

[0019] Hydrogen peroxide: 27.5%-35%;

[0020] Potassium nitrate or sodium fluoride: 1%-3%;

[0021] Any one of sodium stannate, sodium pyrophosphate or sodium silicate: 2%-4%;

[0022] Deionized water: 60%-65%;

[0023] Mixture B consists of the following components in terms of mass percentage:

[0024] Carbomer or polyacrylic acid: 5%-14%;

[0025] Triethanolamine: 3%-5%;

[0026] Either magnesium sulfate or magnesium silicate: 1%-2%;

[0027] Either glycerol or propylene glycol: 20%-30%;

[0028] Deionized water: 45%-62%.

[0029] The aforementioned teeth whitening gel is made of a mixture A and a mixture B with a component ratio of 1:1.

[0030] Wherein, according to mass percentage, mixed solution A is composed of the following components:

[0031] Hydrogen peroxide: 34%;

[0032] Potassium nitrate or sodium fluoride: 3%;

[0033] Any one of sodium stannate, sodium pyrophosphate or sodium silicate: 3%;

[0034] Deionized water: 60%;

[0035] Mixture B consists of the following components in terms of mass percentage:

[0036] Carbomer or polyacrylic acid: 10%;

[0037] Triethanolamine: 5%;

[0038] Either magnesium sulfate or magnesium silicate: 1.5%;

[0039] Either glycerol or propylene glycol: 27%;

[0040] Deionized water: 56.5%.

[0041] A method for preparing a teeth whitening gel comprises the following steps:

[0042] Step (A), preparing mixed solution A;

[0043] (A1) preparing a hydrogen peroxide solution by mixing deionized water and hydrogen peroxide, wherein the deionized water is 37.5%-48% and the hydrogen peroxide is 27.5%-35% by weight;

[0044] (A2) adding 2-4% by weight of any one of sodium stannate, sodium pyrophosphate or sodium silicate to the hydrogen peroxide solution and stirring uniformly at a stirring speed of 200-600 rpm for 5-10 minutes to form a semi-finished mixed solution A;

[0045] (A3) Add 12%-27.5% by weight of deionized water to the semi-finished mixed solution A after stirring, and stir again at a stirring speed of 500-800 rpm for 30-60 minutes to form a pre-finished mixed solution A;

[0046] (A4) Add 1% to 3% by weight of potassium nitrate or sodium fluoride to the pre-mixed solution A after stirring, and stir again at a stirring speed of 500 to 800 rpm for 10 to 20 minutes to complete the preparation of the mixed solution A;

[0047] Step (B), preparing mixed solution B;

[0048] (B1) adding carbomer or polyacrylic acid to deionized water and allowing to swell for 24 hours to form a carbomer or polyacrylic acid solution, wherein the carbomer or polyacrylic acid is 5%-14% by mass and the deionized water is 45%-62% by mass;

[0049] (B2) stirring the swollen carbomer or polyacrylic acid solution at a constant temperature of 45-65°C, a stirring speed of 500-900 rpm, and a stirring time of 1-2 hours;

[0050] (B3) adding 3% to 5% by weight of triethanolamine to the thermostirred carbomer or polyacrylic acid solution, and stirring evenly at a stirring speed of 200 to 600 rpm for 5 to 10 minutes. The pH value of the carbomer or polyacrylic acid solution is adjusted to between 9.5 and 10.5 using triethanolamine to form a semi-finished mixed solution B.

[0051] (B4) adding 1% to 2% by weight of either magnesium sulfate or magnesium silicate to the semi-finished mixed solution B, and stirring evenly at a stirring speed of 200 to 600 rpm for 5 to 10 minutes to form a pre-finished mixed solution B;

[0052] (B5) adding 20% ​​to 30% by weight of either propylene glycol or propylene glycol to the uniformly stirred pre-finished mixed solution B in stages to complete the preparation of the mixed solution B;

[0053] Step (C) is to mix the mixed solution A prepared in step (A) and the mixed solution B prepared in step (B) in a ratio of 1:1 by mass through a double-tube conveyor before use to complete the preparation of the teeth whitening gel.

[0054] The preparation method of the aforementioned tooth whitening gel comprises the following steps:

[0055] Step (A), preparing mixed solution A;

[0056] (A1) Deionized water and hydrogen peroxide are mixed to prepare a hydrogen peroxide solution, wherein the deionized water is 40% and the hydrogen peroxide is 34% by weight;

[0057] (A2) adding 3% by weight of any one of sodium stannate, sodium pyrophosphate or sodium silicate to the hydrogen peroxide solution and stirring the mixture uniformly at a stirring speed of 400 rpm for 8 minutes to form a semi-finished mixed solution A;

[0058] (A3) Add 20% by weight of deionized water to the semi-finished mixed solution A after stirring, and stir again at a stirring speed of 700 rpm for 50 minutes to form a pre-finished mixed solution A;

[0059] (A4) Add 3% by weight of potassium nitrate or sodium fluoride to the pre-mixed solution A after stirring, and stir again at a stirring speed of 700 rpm for 15 minutes to complete the preparation of the mixed solution A;

[0060] Step (B), preparing mixed solution B;

[0061] (B1) adding either carbomer or polyacrylic acid to deionized water and allowing to swell for 24 hours to form a carbomer or polyacrylic acid solution, wherein the carbomer or polyacrylic acid is 10% by mass and the deionized water is 56.5% by mass;

[0062] (B2) Stirring the swollen carbomer or polyacrylic acid solution at a constant temperature of 60°C, a stirring speed of 700 rpm, and a stirring time of 1.5 h;

[0063] (B3) adding 5% by weight of triethanolamine to the carbomer or polyacrylic acid solution after constant temperature stirring, and stirring evenly at a stirring speed of 500 rpm for 8 minutes. The pH value of the carbomer or polyacrylic acid solution is adjusted to 10 with triethanolamine to form a semi-finished mixed solution B;

[0064] (B4) Add 1.5% by weight of either magnesium sulfate or magnesium silicate to the semi-finished mixed solution B, and stir evenly at a stirring speed of 500 rpm for 8 minutes to form a pre-finished mixed solution B;

[0065] (B5) adding 27% by weight of either propylene glycol or propylene glycol to the uniformly stirred pre-finished mixed solution B in stages to complete the preparation of the mixed solution B;

[0066] Step (C) is to mix the mixed solution A prepared in step (A) and the mixed solution B prepared in step (B) in a ratio of 1:1 by mass through a double-tube conveyor before use to complete the preparation of the teeth whitening gel.

[0067] The method for preparing the teeth whitening gel (B5) is to add 20% to 30% by weight of either propylene glycol or propylene glycol in stages to prepare the mixed solution B, which specifically includes the following steps:

[0068] (B51), add either propylene glycol or propylene glycol, accounting for half of the total amount, stirring at a speed of 800-1000 rpm and a stirring time of 1-2 hours;

[0069] (B52), add either propylene glycol or propylene glycol, accounting for one-quarter of the total amount, stirring at a speed of 500-800 rpm and a stirring time of 2-3 hours;

[0070] (B53), finally add either propylene glycol or propylene glycol, accounting for one quarter of the total amount, stirring at a speed of 700-800 rpm and a stirring time of 1-2 h to complete the preparation of mixed solution B.

[0071] The method for preparing the teeth whitening gel (B5) is to add 27% by weight of either propylene glycol or propylene glycol in stages to complete the preparation of the mixed solution B, which specifically includes the following steps:

[0072] (B51), adding either propylene glycol or propylene glycol, accounting for half of the total amount, with a stirring speed of 900 rpm and a stirring time of 1.5 h;

[0073] (B52), adding either propylene glycol or propylene glycol, accounting for one-quarter of the total amount, with a stirring speed of 700 rpm and a stirring time of 2.5 h;

[0074] (B53), finally add either propylene glycol or propylene glycol, accounting for one quarter of the total amount, with a stirring speed of 600 rpm and a stirring time of 1.5 h to complete the preparation of mixed solution B.

[0075] The aforementioned method for preparing the teeth whitening gel, step (C), comprises mixing the teeth whitening gel before use through a double-tube conveyor to complete the preparation of the teeth whitening gel. The double-tube conveyor includes a double-tube tank body, the double-tube tank body including two identical single tubes arranged in parallel, the two identical single tubes respectively containing mixed liquid A and mixed liquid B, and the lower ends of the two identical single tubes are connected to form a mixing chamber of the double-tube tank body, and the lower end of the mixing chamber is screwed with a discharge head.

[0076] A double-tube push rod is provided in the upper end of the two identical single tubes. The double-tube push rod comprises two identical push rods arranged in parallel. The push rods are inserted into the single tubes at corresponding positions.

[0077] When the push rod is pushed again, the mixed liquid A or mixed liquid B is placed in the single tube and squeezed into the mixing chamber for mixing, and the teeth whitening gel prepared by mixing the mixed liquid A and the mixed liquid B is squeezed out through the discharge head.

[0078] The beneficial effects of the present invention are: the tooth whitening gel of the present invention and the preparation method thereof have the following advantages:

[0079] (1) Adding either carbomer or polyacrylic acid can inhibit the ineffective decomposition of hydrogen peroxide caused by metal ions in the teeth, increase the viscosity of the tooth whitening gel, reduce the fluidity on the tooth surface during use, and prevent damage to the gums;

[0080] (2) Add triethanolamine to maintain the pH of the tooth bleaching gel at 9.5-10.5, which is the optimal pH range for the effective decomposition of hydrogen peroxide;

[0081] (3) Add potassium nitrate, which has anti-allergic effects and reduces the sensitivity of hydrogen peroxide to teeth.

[0082] (4) By mixing the prepared mixed solution A and mixed solution B through a unique double-tube conveyor before use, it is possible to prevent the mixed solution A and mixed solution B from mixing prematurely and inhibiting the whitening effect of the teeth whitening gel;

[0083] (5) During the preparation of the mixed solution B, either propylene glycol or propylene glycol (glycerin) is added in batches to gradually adjust the viscosity of the mixed solution B to ensure that the viscosity of the teeth whitening gel is most suitable for teeth. BRIEF DESCRIPTION OF THE DRAWINGS

[0084] FIG1 is a process flow chart of a method for preparing a tooth whitening gel according to the present invention;

[0085] FIG2 is a schematic structural diagram of a double-tube conveyor applicable to the method for preparing the tooth whitening gel of the present invention.

[0086] The markings in the accompanying drawings are as follows:

[0087] 1: Double-tube tank body; 101: Single tube; 2: Mixing bin; 3: Discharge head; 4: Double-tube push rod; 401: Push rod. DETAILED DESCRIPTION

[0088] The present invention will be further described below with reference to the accompanying drawings.

[0089] Specific embodiment 1: The tooth whitening gel of the present invention is prepared by using a mixture A and a mixture B with a component ratio of 1:1.

[0090] Wherein, according to mass percentage, mixed solution A is composed of the following components:

[0091] Hydrogen peroxide: 27.5%-35%;

[0092] Potassium nitrate or sodium fluoride: 1%-3%;

[0093] Any one of sodium stannate, sodium pyrophosphate or sodium silicate: 2%-4%;

[0094] Deionized water: 60%-65%;

[0095] Mixture B consists of the following components in terms of mass percentage:

[0096] Carbomer or polyacrylic acid: 5%-14%;

[0097] Triethanolamine: 3%-5%;

[0098] Either magnesium sulfate or magnesium silicate: 1%-2%;

[0099] Either glycerol or propylene glycol: 20%-30%;

[0100] Deionized water: 45%-62%.

[0101] Specific embodiment 2: Example of the optimal formula of the tooth whitening gel of the present invention:

[0102] It is made of mixed liquid A and mixed liquid B with a component ratio of 1:1.

[0103] Wherein, according to mass percentage, mixed solution A is composed of the following components:

[0104] Hydrogen peroxide: 34%;

[0105] Potassium nitrate or sodium fluoride: 3%;

[0106] Any one of sodium stannate, sodium pyrophosphate or sodium silicate: 3%;

[0107] Deionized water: 60%;

[0108] Mixture B consists of the following components in terms of mass percentage:

[0109] Carbomer or polyacrylic acid: 10%;

[0110] Triethanolamine: 5%;

[0111] Either magnesium sulfate or magnesium silicate: 1.5%;

[0112] Either glycerol or propylene glycol: 27%;

[0113] Deionized water: 56.5%.

[0114] The raw materials used in the present invention include any one of potassium nitrate or sodium fluoride; any one of sodium stannate, sodium pyrophosphate or sodium silicate; any one of carbomer or polyacrylic acid; any one of magnesium sulfate or magnesium silicate; and any one of propylene glycol or propylene glycol (glycerin). The selection of the above substances is determined based on the actual price and convenience of purchasing the raw materials, because the chemical properties of the substances play the same role in the preparation process of the teeth whitening gel, and there is no distinction between good and bad.

[0115] Specific Example 3: Example of the optimal formula of the tooth whitening gel of the present invention (including specific raw material selection):

[0116] It is made of mixed liquid A and mixed liquid B with a component ratio of 1:1.

[0117] Wherein, according to mass percentage, mixed solution A is composed of the following components:

[0118] Hydrogen peroxide: 34%;

[0119] Sodium fluoride: 3%;

[0120] Sodium silicate: 3%;

[0121] Deionized water: 60%;

[0122] Mixture B consists of the following components in terms of mass percentage:

[0123] Polyacrylic acid: 10%;

[0124] Triethanolamine: 5%;

[0125] Magnesium silicate: 1.5%;

[0126] Glycerol: 27%;

[0127] Deionized water: 56.5%.

[0128] Specific embodiment 4: A method for preparing a tooth whitening gel, comprising the following steps:

[0129] Step (A), preparing mixed solution A;

[0130] (A1) preparing a hydrogen peroxide solution by mixing deionized water and hydrogen peroxide, wherein the deionized water is 37.5%-48% and the hydrogen peroxide is 27.5%-35% by weight;

[0131] (A2) adding 2-4% by weight of any one of sodium stannate, sodium pyrophosphate or sodium silicate to the hydrogen peroxide solution and stirring uniformly at a stirring speed of 200-600 rpm for 5-10 minutes to form a semi-finished mixed solution A;

[0132] (A3) Add 12%-27.5% by weight of deionized water to the semi-finished mixed solution A after stirring, and stir again at a stirring speed of 500-800 rpm for 30-60 minutes to form a pre-finished mixed solution A;

[0133] (A4) Add 1% to 3% by weight of potassium nitrate or sodium fluoride to the pre-mixed solution A after stirring, and stir again at a stirring speed of 500 to 800 rpm for 10 to 20 minutes to complete the preparation of the mixed solution A;

[0134] Step (B), preparing mixed solution B;

[0135] (B1) adding carbomer or polyacrylic acid to deionized water and allowing to swell for 24 hours to form a carbomer or polyacrylic acid solution, wherein the carbomer or polyacrylic acid is 5%-14% by mass and the deionized water is 45%-62% by mass;

[0136] (B2) stirring the swollen carbomer or polyacrylic acid solution at a constant temperature of 45-65°C, a stirring speed of 500-900 rpm, and a stirring time of 1-2 hours;

[0137] (B3) adding 3% to 5% by weight of triethanolamine to the thermostirred carbomer or polyacrylic acid solution, and stirring evenly at a stirring speed of 200 to 600 rpm for 5 to 10 minutes. The pH value of the carbomer or polyacrylic acid solution is adjusted to between 9.5 and 10.5 using triethanolamine to form a semi-finished mixed solution B.

[0138] (B4) adding 1% to 2% by weight of either magnesium sulfate or magnesium silicate to the semi-finished mixed solution B, and stirring evenly at a stirring speed of 200 to 600 rpm for 5 to 10 minutes to form a pre-finished mixed solution B;

[0139] (B5) adding 20% ​​to 30% by weight of either propylene glycol or propylene glycol to the uniformly stirred pre-finished mixed solution B in stages to complete the preparation of the mixed solution B;

[0140] Step (C) is to mix the mixed solution A prepared in step (A) and the mixed solution B prepared in step (B) in a ratio of 1:1 by mass through a double-tube conveyor before use to complete the preparation of the teeth whitening gel.

[0141] Preferably, (B5) is to add 20% to 30% by mass of either propylene glycol or propylene glycol in stages to complete the preparation of the mixed solution B, which specifically includes the following steps:

[0142] (B51), add either propylene glycol or propylene glycol, accounting for half of the total amount, stirring at a speed of 800-1000 rpm and a stirring time of 1-2 hours;

[0143] (B52), add either propylene glycol or propylene glycol, accounting for one-quarter of the total amount, stirring at a speed of 500-800 rpm and a stirring time of 2-3 hours;

[0144] (B53), finally add either propylene glycol or propylene glycol, accounting for one quarter of the total amount, stirring at a speed of 700-800 rpm and a stirring time of 1-2 h to complete the preparation of mixed solution B.

[0145] The principle of adding 27% by mass of either propylene glycol or propylene glycol (glycerol) in stages of the present invention is as follows: step (B51) is to stir the powdered magnesium sulfate, the semi-finished mixed solution B and the propylene glycol or propylene glycol (glycerol) at high speed and uniformly, so the rotation speed is controlled at 800-1000 rpm; step (B52) is to control the rotation speed at 500-800 rpm, which is relatively slower than (B51) and takes longer time to better blend the components; step (B53) is to control the rotation speed at 700-800 rpm for 1-2 hours to allow the components in the pre-finished mixed solution B to fully react, which has a better effect, thereby completing the preparation of the mixed solution B.

[0146] Specific embodiment 5: A method for preparing a tooth whitening gel, comprising the following steps:

[0147] Step (A), preparing mixed solution A;

[0148] (A1) Deionized water and hydrogen peroxide are mixed to prepare a hydrogen peroxide solution, wherein the deionized water is 40% and the hydrogen peroxide is 34% by weight;

[0149] (A2) adding 3% by weight of any one of sodium stannate, sodium pyrophosphate or sodium silicate to the hydrogen peroxide solution and stirring the mixture uniformly at a stirring speed of 400 rpm for 8 minutes to form a semi-finished mixed solution A;

[0150] (A3) Add 20% by weight of deionized water to the semi-finished mixed solution A after stirring, and stir again at a stirring speed of 700 rpm for 50 minutes to form a pre-finished mixed solution A;

[0151] (A4) Add 3% by weight of potassium nitrate or sodium fluoride to the pre-mixed solution A after stirring, and stir again at a stirring speed of 700 rpm for 15 minutes to complete the preparation of the mixed solution A;

[0152] Step (B), preparing mixed solution B;

[0153] (B1) adding either carbomer or polyacrylic acid to deionized water and allowing to swell for 24 hours to form a carbomer or polyacrylic acid solution, wherein the carbomer or polyacrylic acid is 10% by mass and the deionized water is 56.5% by mass;

[0154] (B2) Stirring the swollen carbomer or polyacrylic acid solution at a constant temperature of 60°C, a stirring speed of 700 rpm, and a stirring time of 1.5 h;

[0155] (B3) adding 5% by weight of triethanolamine to the carbomer or polyacrylic acid solution after constant temperature stirring, and stirring evenly at a stirring speed of 500 rpm for 8 minutes. The pH value of the carbomer or polyacrylic acid solution is adjusted to 10 with triethanolamine to form a semi-finished mixed solution B;

[0156] (B4) Add 1.5% by weight of either magnesium sulfate or magnesium silicate to the semi-finished mixed solution B, and stir evenly at a stirring speed of 500 rpm for 8 minutes to form a pre-finished mixed solution B;

[0157] (B5) adding 27% by weight of either propylene glycol or propylene glycol to the uniformly stirred pre-finished mixed solution B in stages to complete the preparation of the mixed solution B;

[0158] Step (C) is to mix the mixed solution A prepared in step (A) and the mixed solution B prepared in step (B) in a ratio of 1:1 by mass through a double-tube conveyor before use to complete the preparation of the teeth whitening gel.

[0159] Among them, preferably, (B5), adding 27% by weight of either propylene glycol or propylene glycol in stages to complete the preparation of mixed solution B, specifically comprising the following steps:

[0160] (B51), adding either propylene glycol or propylene glycol, accounting for half of the total amount, with a stirring speed of 900 rpm and a stirring time of 1.5 h;

[0161] (B52), adding either propylene glycol or propylene glycol, accounting for one-quarter of the total amount, with a stirring speed of 700 rpm and a stirring time of 2.5 h;

[0162] (B53), finally add either propylene glycol or propylene glycol, accounting for one quarter of the total amount, with a stirring speed of 600 rpm and a stirring time of 1.5 h to complete the preparation of mixed solution B.

[0163] In step (C) of the present invention, the preparation of the teeth whitening gel is completed by mixing through a double-tube conveyor before use. As shown in FIG2 , the double-tube conveyor includes a double-tube tank body 1, and the double-tube tank body 1 includes two identical single tubes 101 arranged in parallel. The two identical single tubes 101 respectively contain mixed liquid A and mixed liquid B, and the lower ends of the two identical single tubes 101 are connected to form a mixing chamber 2 of the double-tube tank body 1. The lower end of the mixing chamber 2 is screwed with a discharge head 3.

[0164] A double-tube push rod 4 is provided in the upper end of the two identical single tubes 101. The double-tube push rod 4 includes two identical push rods 401 provided in parallel. The push rods 401 are inserted into the single tubes 101 at corresponding positions.

[0165] When the push rod 401 is pushed again, the single tube 101 is placed with the mixed liquid A or the mixed liquid B, squeezed into the mixing chamber 2 for mixing, and the teeth whitening gel prepared by mixing the mixed liquid A and the mixed liquid B is squeezed out through the discharge head 3. Moreover, the same push rod and the same single tube can achieve a 1:1 combination of the mass components of the mixed liquid A and the mixed liquid B.

[0166] Comparison of viscosity test data: According to the preparation method of the tooth whitening gel of the present invention, the optimal solution, the viscosity test data obtained are as shown in Table 1 below, which can obtain the viscosity of the tooth whitening gel of the present invention. The viscosity effect is the best, which solves the problem of large fluidity of the tooth whitening gel during use, reduces the flow of solution from the tooth surface to the gums or oral cavity, oxidizes the oral soft tissue or mucosa, and reduces the pain of consumers.

[0167] Table 1 Viscosity test data (at 25°C)

[0168]

[0169] Comparison of teeth whitening efficacy: Three groups of extracted teeth (young adults: 18-29, young-middle-aged adults: 30-39, and middle-aged adults: 40-49) were collected, with 30 teeth in each group, for a total of 90 teeth. All teeth were intact, without fillings or other defects. Auxiliary equipment: a cold light whitening device (C-Bright).

[0170] The tooth whitening gel prepared in the present invention was applied to three groups of 10 isolated teeth, respectively, with a coating thickness of 0.5 mm, light brightness of High, and illumination time of 20 min.

[0171] The control substance, American White Teeth Whitening Gel, was applied to 10 excised teeth in each of the three groups with a coating thickness of 0.5 mm, light intensity of High, and illumination time of 20 min.

[0172] The control substance, SDI Limited Southern Dental Whitening Gel, was applied to 10 excised teeth in each of the three groups with a coating thickness of 0.5 mm, light intensity of High, and illumination time of 20 min.

[0173] The data after testing with the cold light whitening instrument (C-Bright model) are shown in Table 2 below.

[0174] Table 2 Comparison of teeth whitening effects

[0175]

[0176] The data in Table 2 above show that the bleaching effect of older teeth is relatively less significant than that of younger teeth during the bleaching process. When performing teeth whitening for people of different age groups, the bleaching plan can be appropriately adjusted according to the actual situation, and the tooth whitening gel of the present invention has the best whitening effect.

[0177] In summary, the tooth whitening gel and preparation method thereof of the present invention have the following advantages:

[0178] (1) Adding either carbomer or polyacrylic acid can inhibit the ineffective decomposition of hydrogen peroxide caused by metal ions in the teeth, increase the viscosity of the tooth whitening gel, reduce the fluidity on the tooth surface during use, and prevent damage to the gums;

[0179] (2) Add triethanolamine to maintain the pH of the tooth bleaching gel at 9.5-10.5, which is the optimal pH range for the effective decomposition of hydrogen peroxide;

[0180] (3) Add potassium nitrate, which has anti-allergic effects and reduces the sensitivity of hydrogen peroxide to teeth.

[0181] (4) By mixing the prepared mixed solution A and mixed solution B through a unique double-tube conveyor before use, it is possible to prevent the mixed solution A and mixed solution B from mixing prematurely and inhibiting the whitening effect of the teeth whitening gel;

[0182] (5) During the preparation of the mixed solution B, either propylene glycol or propylene glycol (glycerin) is added in batches to gradually adjust the viscosity of the mixed solution B to ensure that the viscosity of the teeth whitening gel is most suitable for teeth.

[0183] The basic principles, main features, and advantages of the present invention are shown and described above. Those skilled in the art should understand that the present invention is not limited to the foregoing embodiments. The foregoing embodiments and descriptions are merely illustrative of the principles of the present invention. Various changes and modifications may be made to the present invention without departing from the spirit and scope of the present invention. Such changes and modifications are intended to fall within the scope of the present invention. The scope of protection claimed in the present invention is defined by the appended claims and their equivalents.

Claims

1. A teeth whitening gel, characterized in that: It is made of mixed liquid A and mixed liquid B with a component ratio of 1:

1. Wherein, according to mass percentage, the mixed solution A is composed of the following components: Hydrogen peroxide: 27.5%-35%; Potassium nitrate or sodium fluoride: 1%-3%; Any one of sodium stannate, sodium pyrophosphate or sodium silicate: 2%-4%; Deionized water: 60% - 65%; In terms of mass percentage, mixed solution B consists of the following components: Carbomer or polyacrylic acid: 5%-14%; Triethanolamine: 3%-5%; Either magnesium sulfate or magnesium silicate: 1%-2%; Any one of propylene glycol or propylene glycol: 20%-30%; Deionized water: 45%-62%.

2. The tooth whitening gel according to claim 1, characterized in that: It is made of mixed liquid A and mixed liquid B with a component ratio of 1:

1. Wherein, according to mass percentage, the mixed solution A is composed of the following components: Hydrogen peroxide: 34%; Potassium nitrate or sodium fluoride: 3%; Any one of sodium stannate, sodium pyrophosphate or sodium silicate: 3%; Deionized water: 60%; In terms of mass percentage, mixed solution B consists of the following components: Carbomer or polyacrylic acid: 10%; Triethanolamine: 5%; Either magnesium sulfate or magnesium silicate: 1.5%; Either propylene glycol or propylene glycol: 27%; Deionized water: 56.5%.

3. The method for preparing the tooth whitening gel according to claim 1, characterized in that: The following steps are included: Step (A), preparing a mixed solution A; (A1) Deionized water and hydrogen peroxide are mixed to prepare a hydrogen peroxide solution, wherein the deionized water is 37.5%-48% and the hydrogen peroxide is 27.5%-35% by weight; (A2), adding 2-4% by weight of any one of sodium stannate, sodium pyrophosphate or sodium silicate to the hydrogen peroxide solution, and stirring evenly at a stirring speed of 200-600 rpm for 5-10 min to form a semi-finished mixed solution A; (A3), add 12%-27.5% by mass of deionized water to the semi-finished mixed solution A after stirring, stir again, the stirring speed is 500-800 rpm, the stirring time is 30-60 min, to form a pre-finished mixed solution A; (A4), adding 1%-3% by weight of potassium nitrate or sodium fluoride to the pre-finished mixed solution A after stirring, and stirring again at a stirring speed of 500-800 rpm for 10-20 min to complete the preparation of the mixed solution A; Step (B), preparing mixed solution B; (B1), adding either carbomer or polyacrylic acid to deionized water and allowing to swell for 24 hours to form a carbomer or polyacrylic acid solution, wherein the carbomer or polyacrylic acid is 5%-14% by mass and the deionized water is 45%-62% by mass; (B2), stirring the swollen carbomer or polyacrylic acid solution at a constant temperature of 45-65° C., a stirring speed of 500-900 rpm, and a stirring time of 1-2 h; (B3), adding 3%-5% by weight of triethanolamine to the carbomer or polyacrylic acid solution after constant temperature stirring, and stirring evenly, the stirring speed is 200-600 rpm, the stirring time is 5-10 min, and the pH value of the carbomer or polyacrylic acid solution is adjusted to between 9.5 and 10.5 by triethanolamine to form a semi-finished mixed solution B; (B4), adding 1%-2% by weight of magnesium sulfate or magnesium silicate to the semi-finished mixed solution B, and stirring evenly at a stirring speed of 200-600 rpm for 5-10 min to form a pre-finished mixed solution B; (B5) adding 20% ​​to 30% by weight of propylene glycol or propylene glycol to the pre-mixed liquid B after being stirred evenly, thereby completing the preparation of the mixed liquid B; Step (C), mixing the mixed solution A prepared in step (A) and the mixed solution B prepared in step (B) in a mass ratio of 1:1 through a double-tube conveyor before use to complete the preparation of the teeth whitening gel.

4. The method for preparing the tooth whitening gel according to claim 3, characterized in that: The following steps are included: Step (A), preparing a mixed solution A; (A1), deionized water and hydrogen peroxide are mixed to prepare a hydrogen peroxide solution, wherein the deionized water accounts for 40% and the hydrogen peroxide accounts for 34% by mass; (A2), adding 3% by weight of any one of sodium stannate, sodium pyrophosphate or sodium silicate to the hydrogen peroxide solution, and stirring evenly at a stirring speed of 400 rpm for 8 minutes to form a semi-finished mixed solution A; (A3), add 20% by weight of deionized water to the semi-finished mixed solution A after stirring, stir again at a stirring speed of 700 rpm for 50 min to form a pre-finished mixed solution A; (A4) After the pre-finished mixed solution A is stirred evenly, add 3% by weight of potassium nitrate or sodium fluoride, and stir again to make it evenly. The stirring speed is 700 rpm and the stirring time is 15 min to complete the preparation of the mixed solution A. Step (B), preparing mixed solution B; (B1), adding either carbomer or polyacrylic acid to deionized water and allowing to swell for 24 hours to form a carbomer or polyacrylic acid solution, wherein the carbomer or polyacrylic acid is 10% by mass and the deionized water is 56.5% by mass; (B2), stirring the swollen carbomer or polyacrylic acid solution at a constant temperature of 60°C, a stirring speed of 700 rpm, and a stirring time of 1.5 h; (B3), adding 5% by weight of triethanolamine to the carbomer or polyacrylic acid solution after constant temperature stirring, and stirring evenly, the stirring speed is 500 rpm, the stirring time is 8 minutes, and the pH value of the carbomer or polyacrylic acid solution is adjusted to 10 by triethanolamine to form a semi-finished mixed solution B; (B4), adding 1.5% by weight of magnesium sulfate or magnesium silicate to the semi-finished mixed solution B, and stirring evenly at a stirring speed of 500 rpm for 8 minutes to form a pre-finished mixed solution B; (B5) adding 27% by weight of either propylene glycol or propylene glycol to the pre-mixed solution B after being stirred evenly, thereby completing the preparation of the mixed solution B; Step (C), mixing the mixed solution A prepared in step (A) and the mixed solution B prepared in step (B) in a mass ratio of 1:1 through a double-tube conveyor before use to complete the preparation of the teeth whitening gel.

5. The method for preparing the tooth whitening gel according to claim 3, characterized in that: (B5), adding 20%-30% by weight of either propylene glycol or propylene glycol in stages to complete the preparation of mixed solution B, which specifically includes the following steps: (B51), add either propylene glycol or propylene glycol, accounting for half of the total amount, with a stirring speed of 800-1000 rpm and a stirring time of 1-2 h; (B52), add one of propylene glycol or propylene glycol, accounting for one quarter of the total amount, stirring at a speed of 500-800 rpm and stirring for 2-3 hours; (B53), finally add either propylene glycol or propylene glycol, accounting for one quarter of the total amount, with a stirring speed of 700-800 rpm and a stirring time of 1-2 h to complete the preparation of mixed solution B.

6. The method for preparing the tooth whitening gel according to claim 4, characterized in that: (B5), adding 27% by weight of either propylene glycol or propylene glycol in stages to complete the preparation of mixed solution B, which specifically includes the following steps: (B51), add either propylene glycol or propylene glycol, accounting for half of the total amount, the stirring speed is 900 rpm, and the stirring time is 1.5 h; (B52), add one of propylene glycol or propylene glycol, accounting for one quarter of the total amount, the stirring speed is 700 rpm, and the stirring time is 2.5 h; (B53), finally add either propylene glycol or propylene glycol, accounting for one quarter of the total amount, with a stirring speed of 600 rpm and a stirring time of 1.5 h to complete the preparation of mixed solution B.

7. The method for preparing the tooth whitening gel according to claim 3, characterized in that: Step (C) is to mix the mixture by a double-tube conveyor before use to complete the preparation of the teeth whitening gel. The double-tube conveyor comprises a double-tube tank body (1), wherein the double-tube tank body (1) comprises two identical single tubes (101) arranged in parallel, wherein the two identical single tubes (101) respectively contain a mixed liquid A and a mixed liquid B, and the lower ends of the two identical single tubes (101) are connected to form a mixing chamber (2) of the double-tube tank body (1), and the lower end of the mixing chamber (2) is screwed with a discharge head (3). A double-tube push rod (4) is arranged in the upper end of the two identical single tubes (101), and the double-tube push rod (4) comprises two identical push rods (401) arranged in parallel, and the push rods (401) are inserted into the single tubes (101) at corresponding positions. When the push rod (401) is pushed again, the mixed liquid A or the mixed liquid B is placed in the single tube (101) and squeezed into the mixing chamber (2) for mixing, and the teeth whitening gel prepared by mixing the mixed liquid A and the mixed liquid B is squeezed out through the discharge head (3).

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