Method for sample-taking, more particularly in an automated manner, nutrient media handling device for a production facility and production facility having the nutrient media handling device

Abstract

The invention is based on a method for sample-taking, more particularly in an automated manner, more particularly passive air sample-taking, in a production facility, more particularly in a pharmaceutical production facility. It is proposed that in at least one method step (16, 26, 30, 34, 38, 40) of the method, samples are taken, more particularly in a fully automated manner, by means of an electrodynamic conveying system (14), more particular an electrodynamic planar conveying system.

Description

[0001] Description

[0002] Method for a, in particular automated, sampling, nutrient media handling device for a production plant and production plant with the nutrient media handling device

[0003] State of the art

[0004] The invention relates to a method for, in particular automated, sampling, in particular passive air sampling, in a production plant, in particular a pharmaceutical production plant, a nutrient media handling device for a production plant and the production plant with the nutrient media handling device.

[0005] Methods for sampling, particularly air sampling, in a production facility, culture media handling devices, and production facilities with the corresponding culture media handling devices are already known. In these known methods, sampling is carried out through manual intervention by operators. For example, this requires stopping production facilities to minimize the risk of injury to an operator and / or providing intervention zones on the production facilities, which can be implemented, for example, using permanently installed gloves and a viewing window, to enable sampling during production. Manual intervention for sampling can lead to unintentional contamination of the culture media.

[0006] The object of the invention is, in particular, to provide a generic method, a generic nutrient media handling device, and a generic production plant with improved properties with regard to contamination risk and productivity. This object is achieved according to the invention by the features of claim 1, claim 9, and claim 10, respectively, while advantageous embodiments and further developments of the invention can be found in the subclaims.

[0007] Disclosure of the invention

[0008] The invention is based on a method for, in particular automated, sampling, in particular for passive air sampling, in a production plant, in particular in a pharmaceutical production plant.

[0009] It is proposed that in at least one method step, sampling be carried out by means of an electrodynamic conveyor system, in particular an electrodynamic planar conveyor system, in particular be carried out fully automatically. By means of the configuration according to the invention, the need for manual operator intervention for sampling can advantageously be kept to a minimum or largely avoided. The risk of contamination due to manual operator intervention in a production environment can advantageously be kept to a minimum. By carrying out sampling by the electrodynamic conveyor system, a production stoppage can advantageously be largely avoided, in particular since sampling can advantageously be enabled during ongoing operation of a production plant, preferably in parallel with production.This can advantageously enable reliable automated sampling, which can be carried out, for example, at four-hour intervals during operation of the production plant. By using the electrodynamic conveyor system for sampling, which can also be used, for example, for other handling processes in the production plant, additional handling units that would be required specifically for sampling can be eliminated, thus advantageously saving costs and assembly and maintenance effort. A reliable retrofit solution for existing production plants can advantageously be implemented. The electrodynamic conveyor system preferably has a design already known to a person skilled in the art. The electrodynamic conveyor system is preferably designed as an electrodynamic planar conveyor system.The electrodynamic conveying system preferably comprises a plurality of, in particular horizontally or vertically aligned, moving surface elements which are equipped with electromagnetic drive elements and are connected to one another, in particular to form a planar movement plane. The electrodynamic conveying system preferably comprises a plurality of electrodynamically movable movers which are movable relative to the moving surface elements, in particular without contact, in particular as a result of an interaction between permanent magnets of the electrodynamically movable movers and the electromagnetic drive elements of the moving surface elements. In particular, the electrodynamic conveying system can detect and evaluate a position of the individual electrodynamically movable movers relative to the moving surface elements in a manner already known to a person skilled in the art in order to control or regulate a movement, an oscillation or the like.The electrodynamically movable mover is to be implemented. Regarding the basic functionality and design of the electrodynamic conveyor system, reference is made, for example, to the XPianar product from Beckhoff Automation GmbH & Co. KG or the XBot® product from Planar Motor Inc. The electrodynamic conveyor system can be part of the production plant or designed as a separate unit, such as a retrofit solution or similar.

[0010] The electrodynamic conveying system preferably comprises at least one receiving unit arranged on the mover, which is intended to receive and / or prevent slipping of at least one nutrient media receiving device on the mover. The term “provided” should be understood in particular to mean specially set up, specially designed, specially equipped and / or specially programmed. The fact that an object is intended for a specific function should be understood in particular to mean that the object fulfills and / or performs this specific function in at least one application and / or operating state. The receiving unit can be designed to be variably adjustable, so that its receiving dimension, in particular receiving height and / or receiving width, can be adjusted depending on at least one dimension of the nutrient media receiving device.The receiving unit can, for example, comprise at least one lateral support element which is intended to prevent slipping of the nutrient media receiving device when the nutrient media receiving device is arranged on the mover, or at least to counteract slipping. The lateral support element preferably comprises at least one surface which runs transversely, in particular at least substantially perpendicularly, to a contact surface of the mover, against which surface the nutrient media receiving device can rest. The term "substantially perpendicular" is intended in particular to define an orientation of a direction relative to a reference direction, wherein the direction and the reference direction, in particular viewed in a projection plane, enclose an angle of 90° and the angle has a maximum deviation of in particular less than 8°, advantageously less than 5°, and particularly advantageously less than 2°.The contact surface of the mover is preferably a surface of the mover against which the standing side of the nutrient media receiving device rests or stands when the nutrient media receiving device is arranged on the mover, in particular directly or indirectly in the case of a design of the mover with an adhesive coating or an adhesive covering.

[0011] Preferably, the lateral support element is arranged on the mover in a positionally adjustable manner. The lateral support element can be arranged on the mover in a positionally adjustable manner or in steps. It is also conceivable for the receiving unit to comprise a plurality of lateral support elements that are arranged on the mover in a positionally adjustable manner. For example, two lateral support elements of the receiving unit are automatically or manually mounted so as to be movable relative to one another in order to adapt to a transverse extent, in particular a diameter, of the nutrient media receiving device in order to enable advantageous lateral support of the nutrient media receiving device during transport. It is also conceivable for the lateral support element(s) to be arranged in a fixed position on the mover, in particular to be arranged interchangeably on the mover, or to be formed integrally with the mover.The term “one-piece” should be understood in particular as meaning at least materially connected, for example by a welding process, an adhesive process, an injection-molding process and / or another process that appears appropriate to the person skilled in the art, and / or advantageously formed in one piece, such as by production from a single casting and / or by production in a single-component or multi-component injection-molding process and advantageously from a single blank.

[0012] Alternatively or additionally, it is conceivable for the receiving unit to have an adhesive coating arranged on the contact surface of the mover, in particular to influence friction between the nutrient media receiving device and the mover, in particular to prevent the nutrient media receiving device from sliding off the mover during transport, in particular due to a strong acceleration of the mover, or to at least counteract the nutrient media receiving device from sliding off the mover during transport, in particular due to a strong acceleration of the mover. In addition, it is also conceivable for more than one mover, in particular at least two movers, of the electrodynamic conveying system to transport the nutrient media receiving device, in particular a Petri dish, preferably together.such as by clamping the nutrient media receiving device between the at least two movers, wherein, for example, each of the at least two movers has at least one clamping extension, or by the nutrient media receiving device resting on the contact surfaces of the at least two movers, wherein the nutrient media receiving device preferably rests at least partially on the contact surface of one of the at least two movers and at least partially on the contact surface of the other of the at least two movers. Further configurations of the receiving unit, the mover and / or the electrodynamic conveying system that appear appropriate to a person skilled in the art for securely receiving and / or arranging the nutrient media receiving device, in particular to enable secure transport of the nutrient media receiving device, are also conceivable.

[0013] Preferably, the electrodynamic conveying system is configured at least for handling, in particular largely for the entire handling of nutrient media for sampling, in particular for passive air sampling. Preferably, the electrodynamic conveying system in the method according to the invention is configured at least for receiving and / or removing the nutrient media from a nutrient media storage area and / or for delivering the nutrient media to and / or transporting them to the nutrient media storage area. Preferably, the electrodynamic conveying system in the method according to the invention is configured at least for transporting the nutrient media to a point of exposure and / or for exposing the nutrient media for a specified duration. In particular, the electrodynamic conveying system in the method according to the invention is configured at least for opening and / or closing the nutrient media receiving devices filled with nutrient media.The electrodynamic conveying system can be configured for additional tasks / handling operations relevant to sampling that appear appropriate to a person skilled in the art. In addition to performing sampling, the electrodynamic conveying system can be provided for handling products in the production facility, in particular for transporting products from one workstation in the production facility to another workstation in the production facility, or the like. This advantageously eliminates the need for additional procurement and installation of special handling units for sampling. Particularly in existing production facilities that already have an electrodynamic conveying system, the inventive design can be implemented in an advantageously simple manner, enabling significant cost-saving potential.

[0014] Furthermore, it is proposed that, in at least one method step, at least one nutrient media receiving device, in particular a Petri dish, is removed and / or transported from a nutrient media storage facility by means of at least one electrodynamically movable mover of the electrodynamic conveying system, in particular by means of one of the aforementioned plurality of electrodynamically movable movers. For example, the mover can already be arranged in the nutrient media storage facility with the nutrient media receiving device arranged on the mover, or the mover can move into the nutrient media storage facility in an unloaded state and pick up the nutrient media receiving device there, before subsequently moving out of the nutrient media storage facility again.It is conceivable that at least one gripper unit or another handling unit deemed appropriate by a person skilled in the art is arranged on the mover and / or in the nutrient media storage, such as, for example, a clamping unit arranged directly on the mover, a robot unit arranged on the nutrient media storage, or the like. The nutrient media receiving device can be arranged on the mover by means of the gripper unit or the handling unit. It is also conceivable that the mover removes the nutrient media receiving device from a type of magazine, wherein, for example, the mover merely passes under a dispensing opening and, for example, triggers dispensing of the nutrient media receiving device from the magazine by means of a trigger extension on the mover.It is also conceivable for more than one mover, in particular at least two movers, of the electrodynamic conveying system to remove and / or transport the nutrient media receiving device, in particular a Petri dish, from the nutrient media storage area, and / or for a mover of the electrodynamic conveying system to be arranged, in particular permanently, in the nutrient media storage area and to push the nutrient media receiving device from a type of storage location, such as a shelf, onto another mover of the electrodynamic conveying system, with the another mover transporting the nutrient media receiving device from the nutrient media storage area. Further configurations of the nutrient media storage area and / or the movers, and / or the interaction of several movers of the electrodynamic conveying system for transporting and / or removing the nutrient media receiving device from the nutrient media storage area that would be deemed appropriate by a person skilled in the art, are also conceivable.Preferably, the nutrient media receiving device is arranged on the same mover throughout the entire sampling process. However, it is also conceivable for the nutrient media receiving device to be transferred to another mover during the sampling process and / or for the nutrient media receiving device to be removed from the mover for a period of time during the entire sampling process and temporarily stored, for example for exposure or the like, and then placed back on the mover or another mover of the electrodynamic conveying system for transport. Preferably, the nutrient media receiving device(s) is / are designed as Petri dishes. Another design of the nutrient media receiving device(s) that would be deemed appropriate by a person skilled in the art is also conceivable. The nutrient media receiving device(s) can be arranged in the nutrient media storage area filled with nutrient media or empty.Preferably, the nutrient media receiving device(s) is / are arranged filled in the nutrient media storage. If the nutrient media receiving device(s) are arranged empty, it is conceivable that a filling station is arranged in the nutrient media storage to enable filling of the nutrient media receiving device(s) before sampling. By means of the configuration according to the invention, a high degree of automation of sampling can advantageously be realized. The need for manual operator intervention for sampling can advantageously be minimized or largely avoided. The risk of contamination due to manual operator intervention in a production environment can advantageously be minimized.By performing sampling using the electrodynamic conveyor system, a production stoppage can be largely avoided, particularly since sampling can be performed during ongoing production operations, preferably in parallel with production. This can advantageously enable reliable automated sampling, for example, at four-hour intervals during production plant operation.

[0015] It is further proposed that, in at least one method step, at least one nutrient media receiving device, in particular a Petri dish, is transported to a detection unit, in particular to a barcode reader, by means of at least one electrodynamically movable mover of the electrodynamic conveying system, in particular by means of one of the aforementioned plurality of electrodynamically movable movers, and a characteristic value, in particular an ID code, of the nutrient media receiving device is detected. Preferably, the same mover that removed and / or transported the nutrient media receiving device from the nutrient media storage area transports the nutrient media receiving device to the detection unit.However, it is also conceivable for the nutrient media receiving device to be transferred from a mover of the electrodynamic conveying system, which removes and / or transports the nutrient media receiving device from the nutrient media storage area, to another mover of the electrodynamic conveying system, with the further mover transporting the nutrient media receiving device to the detection unit after the transfer. The detection unit is preferably designed as an optical detection unit, such as a camera, a laser scanner, an infrared scanner, or the like. The detection unit is preferably designed as a barcode reader, a QR code reader, or another reader that appears appropriate to a person skilled in the art and is configured to detect a machine-readable code. The detection unit is preferably connected for data purposes to a computing unit of a nutrient media handling device of the production plant.In particular, a characteristic of the nutrient media receiving device is recorded by means of the recording unit and transmitted to the computing unit for processing and / or storage. Preferably, the characteristic of the nutrient media receiving device is provided for identifying the nutrient media receiving device. The characteristic of the nutrient media receiving device is preferably designed as an ID code, preferably in the form of a barcode or a QR code or the like. The recording of the characteristic of the nutrient media receiving device is preferably carried out for documentation purposes of the sampling. The recording unit can be arranged at an exit of the nutrient media storage area or at another position in the production plant that appears appropriate to a person skilled in the art. Preferably, the nutrient media receiving device is provided with an identification code, in particular when the characteristic of the nutrient media receiving device is arranged in the form of a sticker, an engraving, an embossing, or the like.The like, on an outer circumference of the nutrient media receiving device, is moved, in particular rotated, relative to the detection unit by means of the mover, preferably in order to enable reliable detection of the characteristic variable of the nutrient media receiving device. However, it is also conceivable for the detection unit to be moved, in particular rotated, relative to the nutrient media receiving device and / or relative to the mover, preferably in order to enable reliable detection of the characteristic variable of the nutrient media receiving device. The embodiment according to the invention can advantageously enable reliable monitoring and / or documentation of a sampling process. A high degree of automation of the sampling process can advantageously be achieved. Reliable automated sampling can advantageously be enabled, which takes place, for example, at four-hour intervals during operation of the production plant.

[0016] Furthermore, it is proposed that, in at least one method step, at least one nutrient media receiving device, in particular the aforementioned nutrient media receiving device, in particular a closed one filled with a nutrient medium, is transported to a closure handling unit by means of at least one electrodynamically movable mover of the electrodynamic conveying system, in particular by means of a mover of the aforementioned plurality of electrodynamically movable movers, by means of which the nutrient media receiving device is opened. The closure handling unit preferably comprises at least one handling element for handling a closure of the nutrient media receiving device. The handling element can be movably mounted or arranged in a fixed position.The handling element can be designed, for example, as a gripper, a suction cup, a vacuum gripper, a clamping gripper, an adhesive gripper, or as another handling element that appears appropriate to a person skilled in the art. For example, it is also conceivable for the handling element to be designed as a guide extension, by means of which an opening, in particular a hinged, closure of the nutrient media receiving device can be effected, in particular a folding opening of the closure as a result of a passing movement or the like. It is also conceivable for the handling element to be arranged on a mover of the electrodynamic conveying system and to be openable or closable as a result of a relative movement of the mover with the handling element and the mover on which the nutrient media receiving device is arranged.Preferably, the nutrient media receiving device is moved relative to the closure handling unit, in particular toward the handling element, for opening by means of the mover. However, it is also conceivable for the handling element to be moved relative to the nutrient media receiving device, in particular toward the nutrient media receiving device, for opening the nutrient media receiving device, in particular to realize opening by a suction force exerted by the handling element, by a gripping-rotating movement of the handling element, by a pivoting movement of the handling element, or by another movement of the handling element. Opening of the nutrient media receiving device preferably occurs as a result of a relative movement between the at least one mover, on which the nutrient media receiving device is arranged, and the closure handling unit, in particular the handling element.Various movement sequences of the relative movement between the at least one mover, on which the nutrient media receiving device is arranged, and the closure handling unit, in particular the handling element, for opening the nutrient media receiving device are conceivable, such as a vertical relative movement between the at least one mover and the closure handling unit, in particular moving the at least one mover towards the handling element until the closure is in contact with the handling element and is held by the handling element, preferably by adhesion forces, by gripping forces, by suction forces, by clamping forces or the like., wherein a vertical or horizontal relative movement then occurs between the at least one mover and the closure handling unit, in particular a vertical movement of the at least one mover away from the handling element, or a relative rotational movement between the at least one mover and the closure handling unit, in particular a rotation of the at least one mover relative to the handling element. The closure handling unit can be provided for opening and / or closing the nutrient media receiving device. In one embodiment of the nutrient media receiving device as a Petri dish, the closure of the nutrient media receiving device, in particular a lid of the Petri dish, preferably remains on the handling element, while a nutrient medium arranged in a lower part of the nutrient media receiving device is exposed, in particular after a movement away from the handling element.However, it is also conceivable for the handling element to alternatively deposit the closure in a storage position after opening. The closure can be designed as a rotary closure, in particular as a screw closure or a bayonet closure or the like, as a mounted closure, as a hinged closure, as a sliding closure or as any other closure that appears appropriate to a person skilled in the art. The closure handling unit is preferably arranged in a close region of the detection unit. It is also conceivable for the detection unit to be integrated into the closure handling unit. A close region should in particular define an area that extends, in particular in a circle, around a unit and has a maximum transverse extent, in particular a diameter, that is in particular less than 1000 mm, preferably less than 600 mm and particularly preferably less than 300 mm.The closure handling unit preferably has a maximum distance relative to the detection unit, which is in particular less than 1000 mm, preferably less than 600 mm, and particularly preferably less than 300 mm. By means of the configuration according to the invention, the need for manual operator intervention to open the nutrient media receiving device can advantageously be avoided. By carrying out the sampling by the electrodynamic conveying system, a production stoppage can advantageously be largely avoided, in particular since sampling can advantageously be enabled during ongoing operation of a production plant, preferably in parallel with production.

[0017] Furthermore, it is proposed that in at least one method step, at least one nutrient medium receiving device, in particular a Petri dish, is transported into an exposure position by means of at least one electrodynamically movable mover of the electrodynamic conveying system, in particular by means of a mover of the previously mentioned plurality of electrodynamically movable movers.Preferably, the exposure position is arranged in the vicinity of the closure handling unit, preferably below the handling element or next to the closure handling unit, wherein in particular a transport of the nutrient media receiving device, in particular of the lower part of the nutrient media receiving device, preferably after opening the nutrient media receiving device, from the handling element, in particular also away from the closure of the nutrient media receiving device held by the handling element, takes place by the mover, such as for example by a movement of the mover along a vertical and / or horizontal direction or the like.Preferably, the exposure position is located relative to the closure handling unit such that the nutrient medium to be exposed, which is arranged in the nutrient media receiving device, is preferably accessible to an air flow, in particular such that a laminar air flow of the production system is influenced as little as possible until it reaches the nutrient media receiving device. However, it is also conceivable for the mover, together with the nutrient media receiving device arranged thereon, in particular the open one, to remain in one position, in particular the exposure position, and for the handling element to be moved away from the mover and the nutrient media receiving device arranged thereon, in particular the open one, in particular in order to expose the nutrient media arranged in the lower part of the nutrient media receiving device.It is also conceivable that the mover, together with the nutrient media receiving device arranged thereon, in particular open, is moved away from the closure handling unit and the nutrient media receiving device is deposited in an exposure position, wherein the mover is moved away from the nutrient media receiving device after being deposited, in particular to perform other tasks within the production facility, and only picks up the nutrient media receiving device again after an exposure period has elapsed. Preferably, the mover, together with the nutrient media receiving device arranged thereon, in particular open, remain in the exposure position for the entire exposure period. Other movements and / or sequences that appear appropriate to a person skilled in the art for realizing an exposure of the nutrient medium arranged in the lower part of the nutrient media receiving device are also conceivable.The inventive design advantageously allows for a high degree of automation in sampling. The need for manual operator intervention to arrange culture media in an exposure position can be advantageously avoided. It can advantageously enable reliable automated sampling, which can be performed, for example, at four-hour intervals during operation of the production facility.

[0018] Furthermore, it is proposed that, in at least one method step, at least one nutrient media receiving device, in particular an open one filled with an exposed nutrient medium, in particular a lower part of the nutrient media receiving device designed as a Petri dish, is transported to a closure handling unit, in particular to the closure handling unit already mentioned, by means of at least one electrodynamically movable mover of the electrodynamic conveying system, in particular by means of one of the aforementioned plurality of electrodynamically movable movers, by means of which the nutrient media receiving device is closed. Preferably, the nutrient media receiving device, in particular an open one filled with an exposed nutrient medium, is transported, preferably after exposure, from the exposure position by means of the mover to the closure handling unit, in particular moved at least in the direction of the handling element.Preferably, at least the lower part of the nutrient media receiving device is moved by the mover in such a way that the lower part of the nutrient media receiving device is brought into contact with the closure, in particular is closed with the closure held on the handling element. Preferably, the, in particular closed, nutrient media receiving device, preferably the closure together with the lower part of the nutrient media receiving device, is moved by means of the mover relative to the handling element, which is in particular designed as an adhesive gripper, in such a way that the closure is released from the handling element. However, it is also conceivable for the handling element to release the closure as a result of deactivation of a holding force, such as a negative pressure, a clamping force or the like.Further actions and / or movements for closing the nutrient media receiving device that appear appropriate to a person skilled in the art are also conceivable, in particular analogous movements and / or sequences to those already mentioned for opening the closure. The inventive design advantageously allows for a high degree of automation of sampling. The need for manual operator intervention to close the nutrient media receiving device can advantageously be avoided. Reliable automated sampling can advantageously be enabled, for example, at four-hour intervals during operation of the production plant.

[0019] It is further proposed that, in at least one method step, at least one nutrient media receiving device, in particular a Petri dish, is transported into a nutrient media storage area, in particular the aforementioned nutrient media storage area, by means of at least one electrodynamically movable mover of the electrodynamic conveying system, in particular by means of one of the aforementioned plurality of electrodynamically movable movers. Preferably, the nutrient media receiving device is transported into the nutrient media storage area by means of the mover after the nutrient media receiving device has been arranged in the exposure position and, in particular, has been closed again.It is conceivable that the mover is arranged together with the nutrient media receiving device in the nutrient media storage area, or that the nutrient media receiving device is moved down from the mover by means of the mover and / or by means of another handling unit deemed appropriate by a person skilled in the art, in particular is removed, and stored in the nutrient media storage area without the mover, in particular until the nutrient media receiving device with the exposed nutrient medium located therein is removed from the nutrient media storage area for evaluation and / or examination. Preferably, the nutrient media storage area is connected to an environment surrounding the production facility via a clean room lock for removal of the nutrient media receiving device with the exposed nutrient medium located therein for evaluation and / or examination purposes.It is conceivable that the nutrient media receiving device, with the exposed nutrient medium contained therein, can be transported by means of the mover through the cleanroom lock for evaluation and / or examination of the sample. Further embodiments that would be deemed appropriate by a person skilled in the art are also conceivable. The embodiment according to the invention advantageously allows a high degree of automation of sampling to be realized. The need for manual operator intervention for sampling can advantageously be minimized or largely avoided. The risk of contamination due to manual operator intervention in a production environment can advantageously be minimized.By performing sampling using the electrodynamic conveyor system, a production stoppage can be largely avoided, particularly since sampling can be advantageously performed during ongoing production operations, preferably in parallel with production. This can advantageously enable reliable automated sampling, for example, at four-hour intervals during production plant operation.

[0020] Furthermore, it is proposed that the electrodynamically movable mover, in particular together with the nutrient media receiving device arranged thereon, is actively moved relative to the closure handling unit, in particular relative to the handling element, in order to open or close a closure, in particular the one already mentioned above, of the nutrient media receiving device. Preferably, the mover, together with the nutrient media receiving device, in particular the closure and the lower part or only with the lower part, is moved towards or away from the handling element of the closure handling unit at least along a vertical direction, in particular in order to open or close the nutrient media receiving device. The vertical direction preferably runs at least substantially perpendicular to the plane of movement formed by at least one or more movement surface elements of the electrodynamic conveying system.Alternatively or additionally, the mover is at least rotated together with the nutrient media receiving device, in particular about a rotation axis of the mover running at least substantially perpendicular to the plane of movement, and / or tilted, in particular about a tilt axis of the mover running at least substantially parallel to the plane of movement, in particular in order to open or close the nutrient media receiving device. "Substantially parallel" is to be understood in particular as an alignment of a direction relative to a reference direction, in particular in a plane, wherein the direction has a deviation from the reference direction of in particular less than 8°, advantageously less than 5° and particularly advantageously less than 2°. Alternative or additional movements of the mover(s) and / or the handling element for opening or closing the nutrient media receiving device are also conceivable.The inventive design advantageously allows for a high degree of sampling automation. The need for manual operator intervention to open and / or close the culture medium receiving device can be advantageously avoided. The risk of contamination due to manual operator intervention in a production environment can advantageously be minimized. Reliable automated sampling can advantageously be enabled, for example, at four-hour intervals during operation of the production facility.

[0021] Furthermore, a nutrient media handling device for a production plant, in particular for the one already mentioned, is proposed, comprising at least one, in particular the one already mentioned, electrodynamic conveying system, in particular an electrodynamic planar conveying system having at least one electrodynamically movable mover, in particular one of the aforementioned plurality of movers, which is provided for handling nutrient media receiving devices, in particular Petri dishes, and having at least one computing unit comprising an operating program by means of which the at least one electrodynamic mover can be controlled or regulated to carry out a method according to the invention. The computing unit can be designed as an independent computing unit or as a computing unit integrated into a main computing unit of the production plant.The movers of the electrodynamic conveying system are preferably specially designed for use in a clean room environment, as is already known to a person skilled in the art from, for example, DE 10 2021 112 269 A1 and DE 10 2023 110 803 A1. By means of the configuration according to the invention, the need for manual operator intervention for sampling can advantageously be minimized or largely avoided. The risk of contamination due to manual operator intervention in a production environment can advantageously be minimized. By carrying out sampling by the electrodynamic conveying system, a production stoppage can advantageously be largely avoided, in particular since sampling can advantageously be enabled during ongoing operation of a production plant, preferably in parallel with production.This can advantageously enable reliable automated sampling, for example, at four-hour intervals during production plant operation. By using the electrodynamic conveyor system for sampling, which can also be used for other handling processes in the production plant, additional handling units that would be required specifically for sampling can be eliminated, thus saving costs, assembly, and maintenance effort. A reliable retrofit solution for existing production plants can advantageously be implemented.

[0022] Furthermore, a production plant, in particular a pharmaceutical production plant, with at least one nutrient media handling device according to the invention is proposed. The production plant is preferably designed for operation in a clean room environment. The production plant can be provided for filling, manufacturing, and / or packaging pharmaceutical products. However, it is also conceivable for the production plant to be provided for filling, manufacturing, and / or packaging other products that appear appropriate to a person skilled in the art, such as foodstuffs or the like. By means of the configuration according to the invention, a production plant can advantageously be provided in which the need for manual operator intervention for sampling can be minimized or largely avoided.The risk of contamination caused by manual operator intervention in a production environment can be advantageously minimized. By performing sampling using the electrodynamic conveyor system, a production stoppage can be largely avoided, particularly since sampling can be advantageously enabled during ongoing production operations, preferably in parallel with production. Reliable automated sampling can be advantageously enabled, for example, at four-hour intervals during production plant operation.By using the electrodynamic conveying system for sampling, which can also be used for other handling processes in the production plant, additional handling units that would be specifically required for sampling can be eliminated, thus advantageously saving costs and assembly and maintenance effort.

[0023] The method according to the invention, the nutrient media handling device according to the invention, and / or the production plant according to the invention are not intended to be limited to the application and embodiment described above. In particular, the method according to the invention, the nutrient media handling device according to the invention, and / or the production plant according to the invention can have a number of individual elements, components, units, and method steps that differs from the number stated herein in order to fulfill a function described herein. Furthermore, in the value ranges specified in this disclosure, values ​​within the stated limits are also to be considered disclosed and can be used arbitrarily.

[0024] Drawings Further advantages will become apparent from the following description of the drawings. The drawings illustrate an exemplary embodiment of the invention. The drawings, the description, and the claims contain numerous features in combination. Those skilled in the art will also expediently consider the features individually and combine them into useful further combinations.

[0025] They show:

[0026] Fig. 1 A production plant according to the invention with at least one nutrient media handling device according to the invention in a schematic representation,

[0027] Fig. 2 shows a detailed view of an electrodynamically movable mover of an electrodynamic conveying system of the nutrient media handling device according to the invention with a nutrient media receiving device arranged on the mover for carrying out a method according to the invention for taking a sample in the production plant according to the invention, wherein the nutrient media receiving device moved by means of the mover is arranged in an action area of ​​a closure handling unit of the nutrient media handling device according to the invention and / or a detection unit of the nutrient media handling device according to the invention, in a schematic representation,

[0028] Fig. 3a is a detailed view of an opening process of the nutrient media receiving device, wherein the nutrient media receiving device is shown in a state of the nutrient media receiving device moved towards the closure handling unit, in a schematic representation,

[0029] Fig. 3b is a detailed view of an opening process of the nutrient media receiving device, wherein the nutrient media receiving device is shown in a state of the nutrient media receiving device moved away from the closure handling unit, in a schematic representation, Fig. 3c is a detailed view of a transport of the opened nutrient media receiving device in an exposure position in a schematic representation,

[0030] Fig. 4a is a detailed view of a closing process of the nutrient media receiving device, wherein the nutrient media receiving device is shown in a state moved from the exposure position into an action area of ​​the closure handling unit, in a schematic representation,

[0031] Fig. 4b shows a detailed view of the closing process of the nutrient media receiving device, wherein the nutrient media receiving device is moved by means of the mover in the direction of the closure arranged on the closure handling unit, in a schematic representation,

[0032] Fig. 4c shows a detailed view of the closing process of the nutrient media receiving device, wherein the nutrient media receiving device is closed with the closure and the closure is released from the closure handling unit by means of a movement of the mover, in a schematic representation,

[0033] Fig. 4d shows a detailed view of the completed closing process of the nutrient media receiving device, wherein the nutrient media receiving device is shown shortly before transport to a nutrient media storage of the nutrient media handling device, in a schematic representation and

[0034] Fig. 5 shows a schematic process flow of the method according to the invention for sampling in a production plant.

[0035] Description of the embodiment

[0036] Figure 1 shows a production plant 12 with at least one nutrient media handling device 44. The production plant 12 is designed in particular as a pharmaceutical production plant. However, it is also conceivable for the production plant 12 to have a different configuration that appears appropriate to a person skilled in the art, such as, for example, a food production plant or the like. The production plant 12 is preferably intended for the production, processing, and / or filling of pharmaceuticals and / or cosmetics. In addition to the nutrient media handling device 44, the production plant 12 preferably comprises further devices and / or units that appear appropriate to a person skilled in the art and are used for the production, processing, and / or filling of pharmaceuticals and / or cosmetics, such as, for example, a sterilization device, a filling device, a closure device, a repackaging device, or the like.

[0037] The nutrient media handling device 44 for the production plant 12 comprises at least one electrodynamic conveying system 14, in particular an electrodynamic planar conveying system, which has at least one electrodynamically movable mover 18, which is provided for handling nutrient media receiving devices 22, in particular Petri dishes (cf. Figures 2 to 4d), and at least one computing unit 46, which comprises an operating program by means of which the at least one electrodynamic mover 18 can be controlled or regulated to carry out a method 10 for a, in particular automated, sampling, in particular passive air sampling, in the production plant 12. The computing unit 46 can be designed as an independent computing unit or as a computing unit integrated into a main computing unit of the production plant 12.

[0038] The electrodynamic conveying system 14 is preferably configured for at least one, in particular largely complete, handling of nutrient media 20 for sampling, in particular for passive air sampling. The electrodynamic conveying system 14 is preferably configured for at least receiving and / or removing the nutrient media 20 from a nutrient media storage 24 and / or for delivering the nutrient media 20 to and / or transporting them to the nutrient media storage 24. The electrodynamic conveying system 14 is preferably configured for at least transporting the nutrient media 20 to a point of exposure and / or for exposing the nutrient media 20 for a specified duration. In particular, the electrodynamic conveying system 14 is configured for at least opening or closing the nutrient media receiving devices 22 filled with nutrient media 20.In addition to carrying out the sampling, the electrodynamic conveying system 14 can be provided for handling products in the production plant 12, in particular for transporting products from one workstation of the production plant 12 to another workstation of the production plant 12 or the like (not shown in detail here).

[0039] The electrodynamic conveyor system 14 preferably has a design already known to a person skilled in the art. The electrodynamic conveyor system 14 is preferably designed as an electrodynamic planar conveyor system. The electrodynamic conveyor system 14 preferably comprises a plurality of, in particular horizontally or vertically oriented, movement surface elements 54 (see also Figures 2 to 4d), which are equipped with electromagnetic drive elements (not shown in detail here) and are connected to one another, in particular to form a planar movement plane 58 (see also Figures 2 to 4d).The electrodynamic conveyor system 14 preferably comprises a plurality of electrodynamically movable movers 18 (only one of the plurality of movers 18 is shown in Figures 2 to 4d), which are movable relative to the movement surface elements 54, in particular without contact, in particular as a result of an interaction of permanent magnets (not shown in detail here) of the electrodynamically movable movers 18 with the electromagnetic drive elements of the movement surface elements 54. In particular, the electrodynamic conveyor system 14 can detect and evaluate a position of the individual electrodynamically movable movers 18 relative to the movement surface elements 54 in a manner already known to a person skilled in the art in order to control or regulate a movement, an oscillation or the like of the electrodynamically movable movers 18.

[0040] The electrodynamic conveying system 14 can have at least one receiving unit arranged on the mover 18 for receiving and / or preventing slipping of the nutrient media receiving device 22 on the mover 18 (indicated by dashed lines above support elements 50 in Figures 2 to 4d). The receiving unit can be designed to be variably adjustable, so that its receiving dimension, in particular the receiving height and / or receiving width, can be adjusted depending on at least one dimension of the nutrient media receiving device 22. The receiving unit can, for example, comprise at least one lateral support element 50, which is provided to prevent slipping of the nutrient media receiving device 22 when the nutrient media receiving device 22 is arranged on the mover 18, or at least to counteract slipping.The lateral support element 50 preferably comprises at least one surface running transversely, in particular at least substantially perpendicularly, to a contact surface of the mover 18, against which the nutrient media receiving device 22 can rest. The lateral support element 50 is preferably arranged on the mover 18 in a positionally adjustable manner. The lateral support element 50 can be arranged on the mover 18 in a positionally adjustable manner or in steps. It is also conceivable for the receiving unit to comprise a plurality of lateral support elements 50 which are arranged on the mover 18 in a positionally adjustable manner. It is also conceivable for the lateral support element(s) 50 to be arranged in a fixed position on the mover 18, in particular to be arranged interchangeably on the mover 18, or to be formed integrally with the mover 18.Alternatively or additionally, it is conceivable for the receiving unit to have an adhesive coating (not shown in more detail here) arranged on the contact surface of the mover 18, in particular to influence friction between the nutrient media receiving device 22 and the mover 18, in particular to prevent the nutrient media receiving device 22 from sliding off the mover 18 during transport, in particular due to a strong acceleration of the mover 18, or to at least counteract the nutrient media receiving device 22 from sliding off the mover 18 during transport, in particular due to a strong acceleration of the mover 18. In addition, it is also conceivable for more than one mover 18, in particular at least two movers 18, of the electrodynamic conveying system 14 to transport the nutrient media receiving device 22, in particular the Petri dish, preferably together.receive, for example by clamping the nutrient media receiving device 22 between the at least two movers 18, wherein, for example, at least one lateral support element 50 is arranged on each of the at least two movers 18, wherein the nutrient media receiving device 22 is clamped between the lateral support elements 50 to form a receptacle. It is also conceivable for the electrodynamic conveying system 14 to be designed free of the receiving unit. Figures 2 to 4d show schematic representations of a, in particular automated, sampling, in particular passive air sampling, in the production plant 12 by means of the nutrient media handling device 44, wherein Figure 5 shows a schematic process flow of the method 10 for, in particular automated, sampling, in particular passive air sampling, in the production plant 12. In at least one process step 16, 26, 30, 34, 38, 40 of the method 10 (cf.Sampling is carried out using the electrodynamic conveying system 14 (see Figure 5), in particular in a fully automated manner. Preferably, the electrodynamic conveying system 14 is used in virtually all process steps 16, 26, 30, 34, 38, 40 of the process 10, in particular for handling the nutrient medium receiving device 22 in which the nutrient medium 20 for sampling is arranged (see in particular the illustration of individual processes in Figures 2 to 4d).

[0041] Preferably, in at least one method step 16 of method 10, the nutrient media receiving device 22, in particular sealed and filled with the nutrient medium 20, is removed and / or transported from the nutrient media storage 24 of the nutrient media handling device 44 by means of the electrodynamically movable mover 18 of the electrodynamic conveying system 14 (see Figure 2). For example, the mover 18 can already be arranged in the nutrient media storage 24 with the nutrient media receiving device 22 arranged on the mover 18, or the mover 18 can move into the nutrient media storage 24 without the nutrient media receiving device 22 and pick up the nutrient media receiving device 22 there, before subsequently moving out of the nutrient media storage 24 again. The nutrient media receiving device 22 is preferably arranged on the same mover 18 throughout the entire sampling process.However, it is also conceivable that the nutrient media receiving device 22 is transferred to another mover (not shown in detail here) of the electrodynamic conveying system 14 during the sampling process and / or that the nutrient media receiving device 22 is removed from the mover 18 for a period of time within the entire sampling process and is temporarily stored, for example for exposure or the like, and is then arranged again on the mover 18 or another mover (not shown in detail here) of the electrodynamic conveying system 14 for transport.

[0042] The nutrient media receiving device(s) 22 is / are preferably designed as a Petri dish. The nutrient media receiving device(s) 22 preferably comprises at least one closure 42 and at least one lower part 48, which can be closed by means of the closure 42. The nutrient medium 20 is / are preferably arranged or can be arranged in the lower part 48. Another embodiment of the nutrient media receiving device(s) 22 that would appear expedient to a person skilled in the art is / are also conceivable. The nutrient media receiving device(s) 22 can be arranged in the nutrient media storage 24 already filled with nutrient media 20 or unfilled. The nutrient media receiving device(s) 22 is / are preferably arranged filled in the nutrient media storage 24.In the case of an unfilled arrangement of the nutrient media receiving device(s) 22 in the nutrient media storage 24, it is conceivable that a filling station (not shown in detail here) is arranged in the nutrient media storage 24 in order to enable filling of the nutrient media receiving device(s) 22 before sampling.

[0043] Preferably, in at least one method step 26 of the method 10, at least the nutrient media receiving device 22, in particular sealed and filled with the nutrient medium 20, is transported to a detection unit 28 of the nutrient media handling device 44 by means of the electrodynamically movable mover 18 of the electrodynamic conveying system 14, and a characteristic, in particular ID code 52, of the nutrient media receiving device 22 is detected (see Figure 2). The detection unit 28 is preferably designed as an optical detection unit, such as a camera, a laser scanner, an infrared scanner, or the like. The detection unit 28 is preferably designed as a barcode reader, a QR code reader, or another machine code reader that appears appropriate to a person skilled in the art and is configured to detect a machine-readable code. The detection unit 28 is preferably connected to the computing unit 46 for data purposes.In particular, a characteristic of the nutrient media receiving device 22 is recorded by means of the recording unit 28 and transmitted to the computing unit 46 for processing and / or storage. The characteristic of the nutrient media receiving device 22 is preferably provided for identifying the nutrient media receiving device 22. The characteristic of the nutrient media receiving device 22 is preferably designed as an ID code 52, preferably in the form of a barcode or a QR code or the like. The recording of the characteristic of the nutrient media receiving device 22 is preferably carried out for documentation purposes of the sampling. The recording unit 28 can be arranged at an exit of the nutrient media storage 24 or at another position in the production system 12 that appears appropriate to a person skilled in the art.Preferably, the nutrient media receiving device 22, in particular when the characteristic of the nutrient media receiving device 22 is arranged, in particular in the form of a sticker, an engraving, an embossing or the like, on an outer circumference of the nutrient media receiving device 22, is moved, in particular rotated, relative to the detection unit 28 by means of the mover 18, preferably in order to enable reliable detection of the characteristic of the nutrient media receiving device 22.

[0044] Preferably, in at least one method step 30 of the method 10, at least the nutrient media receiving device 22, in particular closed and filled with the nutrient medium 20, is transported by means of the electrodynamically movable mover 18 of the electrodynamic conveying system 14 to a closure handling unit 32 of the nutrient media handling device 44, by means of which the nutrient media receiving device 22 is opened (cf. Figures 2 to 3b). The closure handling unit 32 is preferably arranged in a close region of the detection unit 28. It is also conceivable for the detection unit 28 to be integrated into the closure handling unit 32. The closure handling unit 32 preferably comprises at least one handling element 56 for handling the closure 42 of the nutrient media receiving device 22. In the exemplary embodiment illustrated in Figures 2 to 4d, the handling element 56 is designed as an adhesive gripper.This advantageously makes it possible to realize a particle-free and energy-efficient gripping process, advantageously eliminating the need for vacuum generation and separate control electronics for the handling element 56. However, the handling element 56 can also have a different design that appears expedient to a person skilled in the art, which is designed for use in an aseptic or sterile working environment or in a clean room working environment. Preferably, the nutrient media receiving device 22 is moved relative to the closure handling unit 32, in particular toward the handling element 56, for opening by means of the mover 18. However, it is also conceivable for the handling element 56 to be moved relative to the nutrient media receiving device 22, in particular toward the nutrient media receiving device 22, for opening the nutrient media receiving device 22.When the nutrient media receiving device 22 is configured as a Petri dish with the removable closure 42, the closure 42 of the nutrient media receiving device 22 preferably remains on the handling element 56, while the lower part 48 of the nutrient media receiving device 22 is moved away from the handling element 56 by means of the mover 18. The electrodynamically movable mover 18 is preferably actively moved relative to the closure handling unit 32, in particular together with the nutrient media receiving device 22 arranged thereon, in order to open the closure 42 of the nutrient media receiving device 22.

[0045] Preferably, in at least one method step 34 of method 10, at least the nutrient media receiving device 22, in particular the lower part 48, which is in particular opened and filled with the nutrient medium 20, is transported into an exposure position 36 by means of the electrodynamically movable mover 18 of the electrodynamic conveying system 14 (see, for example, Figure 3b). Figure 3c shows an additional or alternative movement of the lower part 48 by means of the mover 18 into an additional or alternative exposure position 60, which is arranged outside a close range of the closure handling unit 32. Figure 4a shows a movement of the lower part 48 by means of the mover 18 after an exposure period has elapsed from the additional or alternative exposure position 60 back to the closure handling unit 32, in particular to close the nutrient media receiving device 22, preferably to close the lower part 48 again with the closure 42.

[0046] The exposure position 36 is preferably arranged in the vicinity of the closure handling unit 32, preferably below the handling element 56, wherein, in particular, the nutrient media receiving device 22, in particular the lower part 48 of the nutrient media receiving device 22, is transported by the mover 18, preferably after opening the nutrient media receiving device 22, away from the handling element 56, in particular also away from the closure 42 of the nutrient media receiving device 22 held by the handling element 56, for example, by a movement of the mover 18 along a vertical direction or the like (see Figure 3b). The exposure position 36 is preferably arranged, viewed along the vertical direction, in a region between the handling element 56 and the movement surface element 54 (see Figure 3b).Transporting the lower part 48 with the nutrient medium 20 located therein by means of the mover 18 into the exposure position 36 can also involve merely a movement in the vertical direction away from the handling element 56. In particular, as long as the nutrient medium 20 can be exposed to air after the nutrient medium receiving device 22 is opened, a movement of the nutrient medium receiving device 22 by means of the mover 18 along a short distance is sufficient.

[0047] Preferably, in at least one method step 38 of method 10, the nutrient media receiving device 22, in particular open and filled with the exposed nutrient medium 20, is transported by means of the electrodynamically movable mover 18 of the electrodynamic conveying system 14 to the closure handling unit 32, by means of which the nutrient media receiving device 22 is closed (see Figures 4a and 4b in this regard). Preferably, the nutrient media receiving device 22, in particular open and filled with the exposed nutrient medium 20, is transported, preferably after exposure, from the exposure position 36, 60 by means of the mover 18 to the closure handling unit 32, in particular moved at least in the direction of the handling element 56 (see Figure 4b in this regard).Preferably, at least the lower part 48 of the nutrient media receiving device 22 is moved by the mover 18 in such a way that the lower part 48 of the nutrient media receiving device 22 is brought into contact with the closure 42 (see Figure 4c), in particular is closed with the closure 42 held on the handling element 56. Preferably, the, in particular closed, nutrient media receiving device 22, preferably the closure 42 together with the lower part 48 of the nutrient media receiving device 22, is moved, in particular rotated and / or tilted, relative to the handling element 56, which is in particular designed as an adhesive gripper, by means of the mover 18 in such a way that the closure 42 is released from the handling element 56 (see Figure 4c).Preferably, the electrodynamically movable mover 18, in particular together with the nutrient media receiving device 22 arranged thereon, is actively moved relative to the closure handling unit 32 in order to close the closure 42 of the nutrient media receiving device 22.

[0048] Preferably, in at least one method step 40 of method 10, at least the nutrient media receiving device 22, in particular sealed and filled with the exposed nutrient medium 20, is transported into the nutrient media storage 24 by means of the electrodynamically movable mover 18 of the electrodynamic conveying system 14 (see Figure 4d). Preferably, the nutrient media receiving device 22 is transported into the nutrient media storage 24 by means of the mover 18 after the nutrient media receiving device 22 has been arranged in the exposure position 36, 60 and, in particular, has been sealed again.It is conceivable that the mover 18 is arranged together with the nutrient media receiving device 22 in the nutrient media storage 24, or that the nutrient media receiving device 22 is moved down from the mover 18, in particular is removed, by means of the mover 18 and / or by means of another handling unit (not shown in detail here) that appears appropriate to a person skilled in the art, and is stored in the nutrient media storage 24 without the mover 18, in particular until the nutrient media receiving device 22 with the nutrient medium 20 located therein and exposed therein is removed from the nutrient media storage 24 for evaluation and / or examination. Further alternative or additional method steps of the method 10 that appear appropriate to a person skilled in the art are also conceivable.

Claims

Claims 1. Method for a, in particular automated, sampling, in particular passive air sampling, in a production plant, in particular a pharmaceutical production plant, characterized in that in at least one method step (16, 26, 30, 34, 38, 40) the sampling is carried out by means of an electrodynamic conveyor system (14), in particular an electrodynamic planar conveyor system, in particular is carried out fully automatically.

2. Method according to claim 1, characterized in that in at least one method step (16) by means of at least one electrodynamically movable mover (18) of the electrodynamic conveying system (14) at least one, in particular closed and filled with a nutrient medium (20), nutrient medium receiving device (22), in particular a Petri dish, is removed and / or transported from a nutrient medium storage (24).

3. Method according to claim 1 or 2, characterized in that in at least one method step (26) by means of at least one electrodynamically movable mover (18) of the electrodynamic conveying system (14) at least one, in particular closed and filled with a nutrient medium (20), nutrient medium receiving device (22), in particular a Petri dish, is transported to a detection unit (28), in particular a barcode reader, and a characteristic, in particular an ID code (52), of the nutrient media receiving device (22) is detected.

4. Method according to one of the preceding claims, characterized in that in at least one method step (30) by means of at least one electrodynamically movable mover (18) of the electrodynamic conveying system (14) at least one, in particular closed and filled with a nutrient medium (20), nutrient medium receiving device (22), in particular a Petri dish, is transported to a closure handling unit (32), by means of which the nutrient media receiving device (22) is opened.

5. Method according to one of the preceding claims, characterized in that in at least one method step (34) by means of at least one electrodynamically movable mover (18) of the electrodynamic conveying system (14) at least one nutrient medium receiving device (22), in particular a Petri dish, in particular an opened one and filled with a nutrient medium (20), is transported into an exposure position (36).

6. Method according to one of the preceding claims, characterized in that in at least one method step (38) by means of at least one electrodynamically movable mover (18) of the electrodynamic conveying system (14) at least one, in particular open and filled with an exposed nutrient medium (20), nutrient medium receiving device (22), in particular a Petri dish, is transported to a closure handling unit (32) by means of which the nutrient media receiving device (22) is closed.

7. Method according to one of the preceding claims, characterized in that in at least one method step (40) by means of at least one electrodynamically movable mover (18) of the electrodynamic conveying system (14) at least one, in particular closed and filled with an exposed nutrient medium (20), nutrient medium receiving device (22), in particular a Petri dish, is transported into a nutrient medium storage (24).

8. Method at least according to claim 4 or 6, characterized in that the electrodynamically movable mover (18), in particular together with the nutrient media receiving device (22) arranged thereon, is actively moved relative to the closure handling unit (32) in order to open or close a closure (42) of the nutrient media receiving device (22).

9. A nutrient media handling device for a production plant, comprising at least one electrodynamic conveying system (14), in particular an electrodynamic planar conveying system, which has at least one electrodynamically movable mover (18) which is provided for handling nutrient media receiving devices (22), in particular Petri dishes, and comprising at least one computing unit (46) which comprises an operating program by means of which the at least one electrodynamic mover (18) can be controlled or regulated to carry out a method according to one of the preceding claims.

10. Production plant, in particular a pharmaceutical production plant, with at least one nutrient media handling device according to claim 9.

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