Multigene stack for rust resistance
By substituting bacterial border sequences with plant genomic sequences in Agrobacterium-mediated gene transfer, the method addresses the challenge of integrating non-endogenous DNA into plants, resulting in genetically modified plants with only plant-derived DNA and enhanced fungal resistance.
Patent Information
- Application Number
- PCT/AU2024/051287
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2023-11-29
- Filing Date
- 2024-11-29
- Publication Date
- 2025-06-05
AI Technical Summary
Current methods for genetically modifying plants using Agrobacterium-mediated gene transfer often result in the integration of bacterial DNA into the plant genome, making it difficult and expensive to screen for plants without non-endogenous DNA sequences.
Development of a transfer DNA (T-DNA) system that substitutes bacterial border sequences with plant genomic sequences, allowing for the creation of genetically modified plants with only plant-derived DNA, and a DNA construct comprising five genes that confer enhanced resistance to fungal pathogens.
The approach enables the production of transgenic plants without bacterial DNA contamination, simplifying screening processes and potentially reducing regulatory hurdles, while also providing enhanced resistance to a wide variety of fungal pathogens.
Smart Images
Figure AU2024051287_05062025_PF_FP_ABST