Antimicrobial polymer material product and preparation method therefor

Abstract

An antimicrobial polymer material product and a preparation method therefor, relating to the technical field of polymer material processing. Photon broadband antibacterial treatment is applied to a polymer material product to obtain the antimicrobial polymer material product; the polymer material includes plastic or rubber; the plastic includes polyethylene or polyvinyl chloride; the rubber includes nitrile butadiene; the polymer material product is an elastomer product; and the elastomer product is a finger cot, a dental dam, a probe sleeve, or a medical catheter. The antimicrobial polymer material product has an excellent inhibitory effect on Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Candida albicans and the like, and has a high antibacterial rate; and the preparation process is simple, has controllable costs, and is suitable for industrial production.

Description

Antimicrobial polymer material product and preparation method thereof Technical Field

[0001] The present disclosure relates to the technical field of polymer material processing, and in particular to an antimicrobial polymer material product and a preparation method thereof. Background Art

[0002] Disposable gloves are a common type of disposable isolation protective gloves, currently widely used in medical examinations, medical care, laboratories, electronic product processing, food processing, fast food services, and other fields. With the continuous development of the world economy and the continuous changes in people's consumption concepts, people have put forward more demands on the functions of gloves.

[0003] Microorganisms (bacteria, viruses, fungi, etc.) are ubiquitous in our daily lives. Some can cause infections in humans and animals, posing a life-threatening threat. For sterile environments (such as biosafety laboratories), minimizing potential biohazards and risks is a crucial consideration.

[0004] Wearing gloves can effectively isolate microorganisms such as bacteria and viruses. Currently, the gloves commonly found on the market are mainly made of materials such as latex, silicone, and PVC plastic. These materials are prone to the growth and reproduction of microorganisms, increasing the risk of users contracting diseases. The current common process for producing antibacterial gloves is to add some antibacterial materials. These antibacterial materials themselves have certain toxicity and low stability. During processing and production, they may decompose to produce toxic substances, causing certain harm to the human body. Chinese patent CN112812261A obtains gloves with antibacterial properties by attaching a layer of cationic weakly acidic water-based polyurethane film to the outside of the nitrile rubber base film. However, these antibacterial materials have poor compatibility with the glove matrix material and are easily dissolved, resulting in limited antibacterial timeliness of the gloves. Some antibacterial materials may not have strong antibacterial ability themselves and cannot effectively inhibit various pathogens. Chinese patent CN114013082A obtains PVC gloves by adding plasticizers, modified nitrile, antibacterial and antiviral powders, calcium zinc stabilizers, viscosity reducers and other ingredients to PVC paste resin. The process flow of this method is relatively cumbersome and the cost is relatively high. Summary of the Invention

[0005] On the one hand, the present disclosure provides a method for processing a polymer material product, comprising: applying photon broadband treatment to the polymer material product; the polymer material comprises plastic or rubber, the plastic is polyethylene or polyvinyl chloride, and the rubber is nitrile.

[0006] In some embodiments, the polymer material product is an elastomeric product.

[0007] In some embodiments, the polymer material product is a glove, a finger cot, a dental dam, a probe cover, or a medical catheter.

[0008] In some embodiments, the treatment method is used to inhibit microorganisms in elastomeric articles.

[0009] In some embodiments, the microorganism comprises one or more of a fungus, a bacterium, and a virus.

[0010] In some embodiments, the fungus comprises one or more of Candida albicans, mold, yeast, and Malassezia.

[0011] In some embodiments, the bacteria include one or more of Gram-positive bacteria and Gram-negative bacteria.

[0012] In some embodiments, the Gram-positive bacteria include one or more of hemolytic Streptococcus, Staphylococcus aureus, Staphylococcus epidermidis, coagulase-negative Staphylococci, Staphylococcus albus, Streptococcus pneumoniae, Propionibacterium acnes, Enterococcus, Enterococcus faecalis, Viridans Streptococcus, and Clostridium difficile.

[0013] In some embodiments, the Gram-negative bacteria include one or more of Salmonella, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Catarrhalis, Shigella dysenteriae, Proteus mirabilis, and Acinetobacter baumannii.

[0014] In some embodiments, the virus comprises one or more of influenza A virus, influenza B virus, herpes simplex virus, norovirus, rotavirus, mumps virus, parvovirus, and poliovirus.

[0015] In some embodiments, the elastomeric article has an inhibition rate of ≥50% against microorganisms.

[0016] In some embodiments, the elastomeric article has an inhibition rate of ≥ 60% against microorganisms.

[0017] In some embodiments, the elastomeric article has a microbial inhibition rate of ≥ 65%.

[0018] In some embodiments, the elastomeric article has an inhibition rate of ≥70% against microorganisms.

[0019] In some embodiments, the elastomeric article has a microbial inhibition rate of ≥ 75%.

[0020] In some embodiments, the elastomeric article has an inhibition rate of ≥ 80% against microorganisms.

[0021] In some embodiments, the elastomeric article has an inhibition rate of ≥ 85% against microorganisms.

[0022] In some embodiments, the elastomeric article has an inhibition rate of ≥ 89% against microorganisms.

[0023] In some embodiments, the photon broadband treatment is performed at a temperature between 15°C and 60°C.

[0024] In some embodiments, the photon broadband treatment is performed at a temperature of 35°C-50°C.

[0025] In some embodiments, the photon broadband treatment requires a temperature increase treatment, and the initial temperature of the temperature increase treatment is 15-40°C.

[0026] In some embodiments, the initial temperature of the temperature-elevated treatment is 20-40°C.

[0027] In some embodiments, the initial temperature of the temperature-elevated treatment is 25-38°C.

[0028] In some embodiments, the initial temperature of the temperature-elevated treatment is 32-38°C.

[0029] In some embodiments, the initial temperature of the temperature-elevated treatment is 35°C.

[0030] In some embodiments, the temperature is increased at a rate of 1-15° C. per minute.

[0031] In some embodiments, the temperature is increased at a rate of 1-10° C. per minute.

[0032] In some embodiments, the temperature increase treatment is performed at a rate of 1-5°C per minute.

[0033] In some embodiments, the temperature increase treatment is performed at a rate of 1-3°C per minute.

[0034] In some embodiments, the temperature increase treatment is performed at a rate of 1-2°C per minute.

[0035] In some embodiments, during the heating process, the temperature is less than or equal to 60°C.

[0036] In some embodiments, during the heating process, the temperature is less than or equal to 55°C.

[0037] In some embodiments, during the heating process, the temperature is less than or equal to 52°C.

[0038] In some embodiments, during the heating process, the temperature is less than or equal to 50°C.

[0039] In some embodiments, the duration of the photon broadband treatment is 60 minutes to 360 minutes.

[0040] In some embodiments, the duration of the photon broadband treatment is 120 minutes to 300 minutes.

[0041] In some embodiments, the photon broadband treatment lasts for 120 minutes to 240 minutes.

[0042] In some embodiments, the duration of the photon broadband treatment is 150 minutes to 240 minutes.

[0043] In some embodiments, the device model to which the antimicrobial treatment is applied is selected from the group consisting of RRK-168, RRK-220, and RRK-390PZ.

[0044] In some embodiments, the device for applying the antimicrobial treatment is model RRK-186.

[0045] In some embodiments, the present disclosure provides a use of an antibacterial capsule for antimicrobial treatment of polymer products.

[0046] In some embodiments, the polymer material includes plastic or rubber, the plastic is polyethylene or polyvinyl chloride, and the rubber is nitrile.

[0047] In some embodiments, the polymer material is an elastomeric material.

[0048] In some embodiments, the elastomeric article comprises a glove, a finger cot, a dental dam, a probe cover, or a medical catheter.

[0049] In some embodiments, the antimicrobial treatment comprises subjecting the elastomeric article to a photonic broadband treatment.

[0050] In some embodiments, the antimicrobial chamber is a photonic antimicrobial chamber.

[0051] In some embodiments, the photon broadband treatment is performed at a temperature between 15°C and 60°C.

[0052] In some embodiments, the photon broadband treatment is performed at a temperature of 35°C-50°C.

[0053] In some embodiments, the photon broadband treatment requires a temperature increase treatment, and the initial temperature of the temperature increase treatment is 15-40°C.

[0054] In some embodiments, the initial temperature of the temperature-elevated treatment is 20-40°C.

[0055] In some embodiments, the initial temperature of the temperature-elevated treatment is 25-38°C.

[0056] In some embodiments, the initial temperature of the temperature-elevated treatment is 32-38°C.

[0057] In some embodiments, the initial temperature of the temperature-elevated treatment is 35°C.

[0058] In some embodiments, the temperature is increased at a rate of 1-15° C. per minute.

[0059] In some embodiments, the temperature is increased at a rate of 1-10° C. per minute.

[0060] In some embodiments, the temperature increase treatment is performed at a rate of 1-5°C per minute.

[0061] In some embodiments, the temperature increase treatment is performed at a rate of 1-3°C per minute.

[0062] In some embodiments, the temperature increase treatment is performed at a rate of 1-2°C per minute.

[0063] In some embodiments, during the heating process, the temperature is less than or equal to 55°C.

[0064] In some embodiments, during the heating process, the temperature is less than or equal to 52°C.

[0065] In some embodiments, during the heating process, the temperature is less than or equal to 50°C.

[0066] In some embodiments, the duration of the photon broadband treatment is 60 minutes to 360 minutes.

[0067] In some embodiments, the duration of the photon broadband treatment is 120 minutes to 300 minutes.

[0068] In some embodiments, the photon broadband treatment lasts for 120 minutes to 240 minutes.

[0069] In some embodiments, the duration of the photon broadband treatment is 150 minutes to 240 minutes.

[0070] In some embodiments, the microorganism comprises one or more of a fungus, a bacterium, and a virus.

[0071] In some embodiments, the fungus comprises one or more of Candida albicans, mold, yeast, and Malassezia.

[0072] In some embodiments, the bacteria include one or more of Gram-positive bacteria and Gram-negative bacteria.

[0073] In some embodiments, the Gram-positive bacteria include one or more of hemolytic Streptococcus, Staphylococcus aureus, Staphylococcus epidermidis, coagulase-negative Staphylococci, Staphylococcus albus, Streptococcus pneumoniae, Propionibacterium acnes, Enterococcus, Enterococcus faecalis, Viridans Streptococcus, or Clostridium difficile.

[0074] In some embodiments, the Gram-negative bacteria include one or more of Salmonella, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Catarrhalis, Shigella dysenteriae, Proteus mirabilis, and Acinetobacter baumannii.

[0075] In some embodiments, the virus comprises one or more of influenza A virus, influenza B virus, herpes simplex virus, norovirus, rotavirus, mumps virus, parvovirus, and poliovirus.

[0076] In one aspect, the present disclosure provides an antimicrobial elastomeric article, wherein the antimicrobial elastomeric article is prepared by the above-mentioned treatment method.

[0077] In one aspect, the present disclosure provides applications of the antimicrobial elastomeric products in the chemical, medical, and food fields.

[0078] Photon broadband, also known as photon broadband antimicrobial technology, is a purely physical antimicrobial technology. It uses a photon broadband generator to irradiate textiles with a low-nuclear field particle beam for a specific period of time, causing them to produce photons. This creates stable, long-lasting antibacterial, mite-removing, odor-removing, and antiviral properties. Currently, photon broadband antimicrobial technology is primarily used for the sterilization and disinfection of textiles.

[0079] For example, Chinese patent CN219662345U discloses a photon sterilization chamber temperature control device, and Guangdong Renrenkang Technology Co., Ltd. (hereinafter referred to as "Renrenkang") discloses a photon antibacterial chamber, whose equipment models are RRK-168, RRK-220, and RRK-390PZ. The corresponding commercial equipment of photon broadband antibacterial technology has also been applied to a variety of textiles. For example, according to Renrenkang, this physical antibacterial method is suitable for textile fabrics, and its application range includes socks, clothes, towels, home textiles, school bags, curtains, etc. In addition, it discloses that the extended use includes using this antibacterial method for antiviral treatment of masks. For example, after treating the KN95 3D three-dimensional folding protective mask, it has an anti-influenza A virus effect. According to public reports, Renrenkang uses this technology, whose principle is to use the effect of low-nuclear field particle beams to irradiate textile items placed in the cabin for about 3 hours, causing them to produce photogranules. This is a purely physical antibacterial technology (https: / / baike.baidu.com / reference / 59104352 / 533aYdO6cr3_z3kATKXZz6mkYCeSPtWouLaFA-BzzqIP0XOpX5nyFIs88sU0sPRoGUTFtY9xadgTmaf4DUhA7P8Yb7VxH-k).

[0080] In some public channels, this type of related technology is also called "photon broadband physical antibacterial", "textile physical antibacterial", etc. (https: / / www.huangye88.com / xiaoduwang / 88-4d12rs86f73398.html). DETAILED DESCRIPTION

[0081] The following is a detailed description of the technical solution of the present disclosure, which does not limit the scope of protection of the present disclosure. Non-essential modifications and adjustments made by others based on the concept of the present disclosure still fall within the scope of protection of the present disclosure.

[0082] Terminology and Sources

[0083] As used herein, “PVC” refers to products made of polyvinyl chloride as the main raw material, and “PE” refers to products made of polyethylene as the main raw material.

[0084] Nitrile gloves, PVC gloves, and PE gloves were purchased from Shandong Yingke Medical Products Co., Ltd.

[0085] Medical surgical masks were purchased from Shandong Yingke Medical Products Co., Ltd. with the manufacturer’s product number YY201-N10. The mask was made of non-woven fabric.

[0086] The photon broadband antibacterial equipment uses RRK-168 produced by Guangdong Renrenkang Technology Co., Ltd.

[0087] The tested strains included Staphylococcus aureus ATCC 6538P, Escherichia coli ATCC 8739, Candida albicans ATCC 10231, Klebsiella pneumoniae ATCC 4352, from the American Type Culture Collection; and Pseudomonas aeruginosa CMCC(B)10104, from the China Medical Culture Collection.

[0088] Example 1 Preparation of antibacterial nitrile gloves

[0089] Nitrile gloves were treated in a photon broadband antibacterial device to produce antibacterial nitrile gloves. The device's processing parameters were set to: voltage 220V, power 2400W, initial chamber temperature set at 35°C, ramped up at a rate of 1-2°C per minute, reaching 45°C within 15 minutes, and ultimately maintained at no more than 50°C. The total treatment time was 180 minutes.

[0090] Example 2 Preparation of antibacterial PVC gloves

[0091] PVC gloves were placed in a photon broadband antibacterial device for treatment to produce antibacterial PVC gloves. The device's treatment parameters were set to: voltage 220V, power 2400W, initial chamber temperature set at 35°C, ramped up at a rate of 1-2°C per minute, reaching 45°C within 15 minutes, and ultimately maintained at no more than 50°C. The total treatment time was 180 minutes.

[0092] Example 3 Preparation of antibacterial PE gloves

[0093] PE gloves were placed in a photon broadband antibacterial device for treatment to produce antibacterial PE gloves. The device's treatment parameters were set to: voltage 220V, power 2400W, initial chamber temperature set at 35°C, ramped up at a rate of 1-2°C per minute, reaching 45°C within 15 minutes, and ultimately maintained at no more than 50°C. The total treatment time was 180 minutes.

[0094] Comparative Example 1 Preparation of Antibacterial Medical Surgical Mask

[0095] Medical surgical masks were placed in a photon broadband antibacterial device for treatment to produce antibacterial medical surgical masks. The device's treatment parameters were set to: voltage 220V, power 2400W, initial chamber temperature set at 35°C, ramped up at a rate of 1-2°C per minute, reaching 45°C within 15 minutes, and ultimately maintained at no more than 50°C. The total treatment time was 180 minutes.

[0096] Comparative Example 2 Preparation of Antibacterial Fabric No. 1

[0097] The content of fabric No. 1 used in Comparative Example 2 is: 92.0% modal and 8.0% spandex.

[0098] Fabric No. 1 was treated in a photon broadband antibacterial device to produce an antibacterial fabric. The device's processing parameters were: voltage 220V, power 2400W, initial chamber temperature set at 35°C, ramped up at a rate of 1-2°C per minute, reaching 45°C within 15 minutes, and ultimately maintained at no more than 50°C. The total treatment time was 180 minutes.

[0099] Comparative Example 3 Preparation of Antibacterial Fabric No. 2

[0100] The content of fabric No. 2 used in Comparative Example 3 is: 91.6% polyester fiber and 8.4% spandex.

[0101] Fabric No. 2 was treated in a photon broadband antibacterial device to produce the antibacterial fabric. The device's processing parameters were: voltage 220V, power 2400W, initial chamber temperature set at 35°C, ramped up at a rate of 1-2°C per minute, reaching 45°C within 15 minutes, and ultimately maintained at no more than 50°C. The total treatment time was 180 minutes.

[0102] Comparative Example 4 Preparation of No. 3 Antibacterial Fabric

[0103] The content of fabric No. 3 used in Comparative Example 4 is: 84.2% cotton and 15.8% polyester fiber.

[0104] Fabric No. 3 was treated in a photon broadband antibacterial device to produce the antibacterial fabric. The device's processing parameters were: voltage 220V, power 2400W, initial chamber temperature set at 35°C, ramped up at a rate of 1-2°C per minute, reaching 45°C within 15 minutes, and ultimately maintained at no more than 50°C. The total treatment time was 180 minutes.

[0105] Comparative Example 5 Preparation of No. 4 Antibacterial Fabric

[0106] The fabric content of No. 4 used in Comparative Example 5 is: 100.0% cotton.

[0107] Fabric No. 4 was treated in a photon broadband antibacterial device to produce the antibacterial fabric. The device's processing parameters were: voltage 220V, power 2400W, initial chamber temperature set at 35°C, ramped up at a rate of 1-2°C per minute, reaching 45°C within 15 minutes, and ultimately maintained at no more than 50°C. The total treatment time was 180 minutes.

[0108] Comparative Example 6 Preparation of No. 5 Antibacterial Fabric

[0109] The content of fabric No. 5 used in Comparative Example 6 is: 84.1% cotton and 15.9% polyester fiber.

[0110] Fabric No. 5 was treated in a photon broadband antibacterial device to produce the antibacterial fabric. The device's processing parameters were: voltage 220V, power 2400W, initial chamber temperature set at 35°C, ramped up at a rate of 1-2°C per minute, reaching 45°C within 15 minutes, and ultimately maintained at no more than 50°C. The total treatment time was 180 minutes.

[0111] Example 4 Antibacterial Performance Test

[0112] The gloves of Examples 1-3, the medical surgical masks of Comparative Example 1, and the fabrics of Comparative Examples 2-6 were tested, with three pieces of each material tested. The antibacterial performance test standards and methods are as follows:

[0113] (1) The gloves were tested using the film method according to GB / T 31402-2015. The specific operation was as follows: take a 5*5cm sample, cover it with a 4*4cm film, add 0.4ml of bacterial solution, and count the colonies after 24 hours of incubation. Calculate the reduction ratio of the colony count between the control sample and the sample after 24 hours of incubation.

[0114] (2) Medical surgical masks are tested according to GB15979-2012 (Appendix C). The specific operation is as follows: 0.75g of the sample is sterilized, 70ml of PBS and 5ml of bacterial solution are added, and the colony count is performed after shaking for a certain period of time. The reduction ratio of the colony count before and after shaking is calculated.

[0115] (3) Fabrics are tested according to GB / T 20944.3-2008.

[0116] The antibacterial test results are shown in Tables 1, 2 and 5.

[0117] The improvement in antibacterial rate was calculated according to Tables 1, 2, and 5. The improvement in antibacterial rate (%) = [(antibacterial rate after treatment - antibacterial rate before treatment) / antibacterial rate before treatment] × 100%. The calculation results are shown in Tables 3, 4, and 6.

[0118] Table 1 Antibacterial performance test results of gloves and medical surgical masks

[0119] (Note: The data shown in Table 1 are mean ± standard deviation)

[0120] Table 2 Antibacterial performance test results of fabrics

[0121] (Note: The data shown in Table 2 are average values)

[0122] Table 3 Improvement in the antibacterial rate of gloves and medical surgical masks

[0123] Table 4 Improvement of antibacterial rate of different fabrics

[0124] Test Example 1 Preparation of Antibacterial Nitrile Gloves (Total Treatment Time: 240 Minutes)

[0125] Nitrile gloves were treated in a photon broadband antibacterial device to produce antibacterial nitrile gloves. The device's processing parameters were set to: voltage 220V, power 2400W, initial chamber temperature set at 35°C, ramped up at a rate of 1-2°C per minute, reaching 45°C within 15 minutes, and ultimately maintained at no more than 50°C. The total treatment time was 240 minutes.

[0126] Test Example 2 Preparation of Antibacterial Nitrile Gloves (Total Treatment Time: 300 Minutes)

[0127] Nitrile gloves were treated in a photon broadband antibacterial device to produce antibacterial nitrile gloves. The device's processing parameters were set to: voltage 220V, power 2400W, initial chamber temperature set at 35°C, ramped up at a rate of 1-2°C per minute, reaching 45°C within 15 minutes, and ultimately maintained at no more than 50°C. The total treatment time was 300 minutes.

[0128] Test Example 3 Preparation of Antibacterial Nitrile Gloves (Total Treatment Time: 360 Minutes)

[0129] Nitrile gloves were treated in a photon broadband antibacterial device to produce antibacterial nitrile gloves. The device's processing parameters were set to: voltage 220V, power 2400W, initial chamber temperature set at 35°C, ramped up at a rate of 1-2°C per minute, reaching 45°C within 15 minutes, and ultimately maintained at no more than 50°C. The total treatment time was 360 minutes.

[0130] Test Example 4 Preparation of Antibacterial PVC Gloves (Total Treatment Time: 240 Minutes)

[0131] PVC gloves were placed in a photon broadband antibacterial device for treatment to produce antibacterial PVC gloves. The device's treatment parameters were set to: voltage 220V, power 2400W, initial chamber temperature set at 35°C, ramped up at a rate of 1-2°C per minute, reaching 45°C within 15 minutes, and ultimately maintained at no more than 50°C. The total treatment time was 240 minutes.

[0132] Test Example 5 Preparation of Antibacterial PVC Gloves (Total Treatment Time: 300 Minutes)

[0133] PVC gloves were placed in a photon broadband antibacterial device for treatment to produce antibacterial PVC gloves. The device's treatment parameters were set to: voltage 220V, power 2400W, initial chamber temperature set at 35°C, ramped up at a rate of 1-2°C per minute, reaching 45°C within 15 minutes, and ultimately maintained at no more than 50°C. The total treatment time was 300 minutes.

[0134] Test Example 6 Preparation of Antibacterial PVC Gloves (Total Treatment Time: 360 Minutes)

[0135] PVC gloves were placed in a photon broadband antibacterial device for treatment to produce antibacterial PVC gloves. The device's treatment parameters were set to: voltage 220V, power 2400W, initial chamber temperature set at 35°C, ramped up at a rate of 1-2°C per minute, reaching 45°C within 15 minutes, and ultimately maintained at no more than 50°C. The total treatment time was 360 minutes.

[0136] Test Example 7 Preparation of Antibacterial PE Gloves (Total Treatment Time: 240 Minutes)

[0137] PE gloves were placed in a photon broadband antibacterial device for treatment to produce antibacterial PE gloves. The device's treatment parameters were set to: voltage 220V, power 2400W, initial chamber temperature set at 35°C, ramped up at a rate of 1-2°C per minute, reaching 45°C within 15 minutes, and ultimately maintained at no more than 50°C. The total treatment time was 240 minutes.

[0138] Test Example 8 Preparation of Antibacterial PE Gloves (Total Treatment Time: 300 Minutes)

[0139] PE gloves were placed in a photon broadband antibacterial device for treatment to produce antibacterial PE gloves. The device's treatment parameters were set to: voltage 220V, power 2400W, initial chamber temperature set at 35°C, ramped up at a rate of 1-2°C per minute, reaching 45°C within 15 minutes, and ultimately maintained at no more than 50°C. The total treatment time was 300 minutes.

[0140] Test Example 9 Preparation of Antibacterial PE Gloves (Total Treatment Time: 360 Minutes)

[0141] PE gloves were placed in a photon broadband antibacterial device for treatment to produce antibacterial PE gloves. The device's treatment parameters were set to: voltage 220V, power 2400W, initial chamber temperature set at 35°C, ramped up at a rate of 1-2°C per minute, reaching 45°C within 15 minutes, and ultimately maintained at no more than 50°C. The total treatment time was 360 minutes.

[0142] Example 5 Antibacterial performance test of gloves with different treatment times

[0143] The gloves of Test Examples 1-9 were tested, with three gloves of each material tested. The antibacterial performance test standards and methods are as follows:

[0144] The gloves were tested using the GB / T 31402-2015 film method. The specific operation is as follows: take a 5*5cm sample, cover it with a 4*4cm film, add 0.4ml of bacterial solution, and count the colonies after 24 hours of incubation. The reduction ratio of the colony count between the control sample and the sample after 24 hours of incubation is calculated.

[0145] The antibacterial test results are shown in Table 5.

[0146] The improvement in antibacterial rate was calculated according to Table 5: Antibacterial rate improvement (%) = [(antibacterial rate after treatment - antibacterial rate before treatment) / antibacterial rate before treatment] × 100%. The calculation results are shown in Table 6.

[0147] Table 5 Antibacterial performance test results of gloves with different treatment times

[0148] (Note: The data shown in Table 5 are mean ± standard deviation)

[0149] Table 6 Improvement of antibacterial rate of gloves at different treatment times

[0150] The experiment found that, unlike the antiviral efficacy of masks treated with broadband photon antibacterial treatment reported in prior art, the antibacterial efficacy of non-woven masks after broadband photon antibacterial treatment was poor against Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Candida albicans (see the results in Table 3). Notably, broadband photon treatment did not improve the antibacterial efficacy of non-woven masks against Candida albicans.

[0151] On the contrary, when the test objects were set to nitrile / PVC / PE products, the antibacterial rates of photon broadband treatment for Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Candida albicans were all greater than 90% (see the results in Table 1), which was a greater improvement compared to masks or different fabrics (see the results in Tables 3 and 4), and had very excellent antibacterial properties.

[0152] The antibacterial efficacy against Candida albicans was demonstrated in nitrile / PVC / PE test materials, compared to other typical targets for photon broadband antibacterial devices (e.g., textiles). (See the results in Tables 3 and 4. The antibacterial rate against Candida albicans in nitrile / PVC / PE products treated with photon broadband increased by ≥100%, and even as high as 120%.) This result is surprising, as candidiasis is a fungal disease caused by Candida species, particularly Candida albicans. This pathogen can invade the skin and mucous membranes, as well as internal organs. Typically classified by the affected site, the two most common syndromes are mucocutaneous candidiasis (e.g., oropharyngeal candidiasis or thrush, esophagitis, and vaginitis) and invasive or deep-organ candidiasis (e.g., candidemia, chronic disseminated or hepatosplenic candidiasis, endocarditis, etc.). Nitrile / PVC / PE products are often used in medical products such as gloves, which may come into contact with the mucous membranes of patients with suboptimal immunity, such as the esophageal and vaginal mucosa. Therefore, the unexpected antibacterial and antimicrobial effects achieved by antimicrobial treatment of these products against Candida albicans are of great practical significance.

[0153] The embodiments described in the present disclosure are merely illustrative examples, and the embodiments of the present disclosure are not subject to the above limitations. Any other changes, modifications, substitutions, combinations, and simplifications that do not deviate from the spirit and principles of the present disclosure shall be considered equivalent replacement methods and shall be included in the scope of protection of the present disclosure.

Claims

1. Processing methods for polymer products, including: Applying broadband photon treatment to polymer material products; The polymer material includes plastic or rubber, the plastic is polyethylene or polyvinyl chloride, and the rubber is nitrile.

2. The processing method according to claim 1, characterized in that: The polymer material product is an elastomer product; Preferably, the elastomeric article is a glove, a finger cot, a dental dam, a probe cot or a medical catheter; Preferably, the treatment method is used to inhibit microorganisms in elastomeric articles; Preferably, the microorganisms include one or more of fungi, bacteria and viruses; Preferably, the fungus includes one or more of Candida albicans, mold, yeast and Malassezia; Preferably, the bacteria include one or more of Gram-positive bacteria and Gram-negative bacteria; Preferably, the Gram-positive bacteria include one or more of hemolytic streptococci, Staphylococcus aureus, Staphylococcus epidermidis, coagulase-negative staphylococci, Staphylococcus albus, Streptococcus pneumoniae, Propionibacterium acnes, Enterococcus, Enterococcus faecalis, Viridans Streptococcus and Clostridium difficile; Preferably, the Gram-negative bacteria include one or more of Salmonella, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Catarrhalis, Shigella dysenteriae, Proteus mirabilis and Acinetobacter baumannii; Preferably, the virus comprises one or more of influenza A virus, influenza B virus, herpes simplex virus, norovirus, rotavirus, mumps virus, parvovirus and poliovirus.

3. The processing method according to claim 2, characterized in that: The inhibition rate of the elastomer product on microorganisms is ≥50%; Preferably, the inhibition rate of the elastomeric product on microorganisms is ≥ 60%; Preferably, the inhibition rate of the elastomeric product on microorganisms is ≥ 65%; Preferably, the inhibition rate of the elastomeric product on microorganisms is ≥ 70%; Preferably, the inhibition rate of the elastomeric product on microorganisms is ≥ 75%; Preferably, the inhibition rate of the elastomeric product on microorganisms is ≥ 80%; Preferably, the inhibition rate of the elastomeric product on microorganisms is ≥ 85%; Preferably, the inhibition rate of the elastomeric product on microorganisms is ≥ 89%.

4. The processing method according to any one of claims 1 to 3, characterized in that: The photon broadband treatment is carried out at a temperature of 15°C-60°C; Preferably, the photon broadband treatment is carried out at a temperature of 35°C-50°C. Preferably, the photon broadband treatment requires a temperature increase treatment, and the initial temperature of the temperature increase treatment is 15-40°C; Preferably, the initial temperature of the heating treatment is 20-40°C; Preferably, the initial temperature of the heating treatment is 25-38°C; Preferably, the initial temperature of the temperature increase treatment is 32-38°C; Preferably, the initial temperature of the heating treatment is 35°C; Preferably, the temperature is increased at a rate of 1-15°C per minute; Preferably, the temperature is increased at a rate of 1-10°C per minute; Preferably, the temperature increase process is performed at a rate of 1-5°C per minute; Preferably, the temperature increase treatment is performed at a rate of 1-3°C per minute; Preferably, the temperature is raised at a rate of 1-2°C per minute. Preferably, during the heating process, the temperature is less than or equal to 60°C; Preferably, during the heating process, the temperature is less than or equal to 55°C; Preferably, during the heating process, the temperature is less than or equal to 52°C; Preferably, during the heating process, the temperature is less than or equal to 50°C; Preferably, the photon broadband treatment lasts for 60 minutes to 360 minutes; Preferably, the photon broadband treatment lasts for 120 minutes to 300 minutes; Preferably, the photon broadband treatment time is 120 minutes to 240 minutes; Preferably, the duration of the photon broadband treatment is 150 minutes to 240 minutes.

5. Use of an antibacterial cabin in antimicrobial treatment of polymer material products, wherein the polymer material comprises plastic or rubber, the plastic is polyethylene or polyvinyl chloride, and the rubber is nitrile; Preferably, the polymer material product is an elastomer product; Preferably, the elastomeric article comprises a glove, a finger cot, a dental dam, a probe cover or a medical catheter.

6. The use according to claim 5, characterized in that The antimicrobial treatment comprises subjecting the elastomeric article to a photonic broadband treatment; Preferably, the antibacterial chamber is a photon antibacterial chamber.

7. The use according to claim 5 or 6, characterized in that The photon broadband treatment is carried out at a temperature of 15°C-60°C; Preferably, the photon broadband treatment is carried out at a temperature of 35°C-50°C; Preferably, the photon broadband treatment requires a temperature increase treatment, and the initial temperature of the temperature increase treatment is 15-40°C; Preferably, the initial temperature of the heating treatment is 20-40°C; Preferably, the initial temperature of the heating treatment is 25-38°C; Preferably, the initial temperature of the temperature increase treatment is 32-38°C; Preferably, the initial temperature of the heating treatment is 35°C; Preferably, the temperature is increased at a rate of 1-15°C per minute; Preferably, the temperature is increased at a rate of 1-10°C per minute; Preferably, the temperature increase process is performed at a rate of 1-5°C per minute; Preferably, the temperature increase treatment is performed at a rate of 1-3°C per minute; Preferably, the temperature increase process is performed at a rate of 1-2°C per minute; Preferably, during the heating process, the temperature is less than or equal to 60°C; Preferably, during the heating process, the temperature is less than or equal to 55°C; Preferably, during the heating process, the temperature is less than or equal to 52°C; Preferably, during the heating process, the temperature is less than or equal to 50°C; Preferably, the photon broadband treatment lasts for 60 minutes to 360 minutes; Preferably, the photon broadband treatment lasts for 120 minutes to 300 minutes; Preferably, the photon broadband treatment time is 120 minutes to 240 minutes; Preferably, the duration of the photon broadband treatment is 150 minutes to 240 minutes.

8. The use according to any one of claims 5 to 7, characterized in that The microorganisms include one or more of fungi, bacteria and viruses; Preferably, the fungus includes one or more of Candida albicans, mold, yeast and Malassezia; Preferably, the bacteria include one or more of Gram-positive bacteria and Gram-negative bacteria; Preferably, the Gram-positive bacteria include one or more of hemolytic streptococci, Staphylococcus aureus, Staphylococcus epidermidis, coagulase-negative staphylococci, Staphylococcus albus, Streptococcus pneumoniae, Propionibacterium acnes, Enterococcus, Enterococcus faecalis, Viridans Streptococcus and Clostridium difficile; Preferably, the Gram-negative bacteria include one or more of Salmonella, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Catarrhalis, Shigella dysenteriae, Proteus mirabilis and Acinetobacter baumannii; Preferably, the virus comprises one or more of influenza A virus, influenza B virus, herpes simplex virus, norovirus, rotavirus, mumps virus, parvovirus and poliovirus.

9. An antimicrobial elastomeric product, characterized in that The antimicrobial elastomeric product is prepared by the treatment method according to any one of claims 2 to 4.

10. Use of the antimicrobial elastomer product according to claim 9 in the fields of chemical industry, medical treatment and food.

Images