Universal dental restoration composition and manufacturing method therefor

Abstract

An embodiment of the present invention provides a universal dental restoration composition having a chameleon effect, the composition comprising: a first unsaturated double bond compound containing at least one selected from the group consisting of a monomer having an unsaturated double bond and an oligomer of a monomer having an unsaturated double bond; an organic-inorganic composite filler having a spherical shape with a first average particle diameter (r1); a second filler with a second average particle diameter (r2); and a photo-initiator, wherein the second filler has a weight percentage of 40 wt% to 50 wt% relative to the total weight of the universal dental restoration composition.

Description

General-purpose dental restorative composition and method for producing the same

[0001] The present invention relates to a general-purpose dental restorative composition and a method for manufacturing the same, and more particularly, to a general-purpose dental restorative composition having a maximized chameleon effect by controlling translucency while using an organic-inorganic composite spherical filler, and a method for manufacturing the same.

[0002] Dental restorative materials are used to repair damaged teeth caused by decay or fracture. These materials should be applied with the patient's tooth color in mind. When applied in a natural, non-disturbing manner, they are considered aesthetically pleasing.

[0003] Typically, a patient's tooth color varies from person to person and depending on the tooth's location (anterior, posterior, enamel, and dentin). Teeth come in a variety of color combinations, ranging from yellow to red to varying shades of light or dark. To match these colors, dentists use a shade guide.

[0004] A shade guide is a color guide for dental restorative materials provided by manufacturers. Even within the same shade, there may be slight variations in color depending on the manufacturer. Therefore, to achieve optimal aesthetic results, dentists must follow the shade guide provided or recommended by the manufacturer.

[0005] Shade guides are generally composed of four groups (A, B, C, D) and numbers such as 1, 2, 3, 3.5, 4, etc. A stands for reddish brown, B stands for reddish yellow, C stands for gray, and D stands for reddish gray. The number following the group indicates the chroma, with higher numbers indicating higher chroma. For example, A1, A2, A3, A3.5, A4 means that in the reddish brown group, A1 has the lowest chroma of reddish brown, and A4 has the highest chroma of reddish brown. The doctor goes through a process called shade taking to compare the color of the patient's teeth according to this shade guide, and uses a dental restorative material of the matching color to restore the patient's teeth, improving the aesthetics and satisfying the patient.

[0006] However, although the above-mentioned various colored dental restorative materials help to improve the aesthetics and satisfaction of patients, they have the inconvenience of having to prepare various dental restorative materials for each individual patient or treatment area. There are dental restorative materials classified into as many as 36 colors, and among them, besides the commonly used A or B series dental restorative materials, restorative materials of other colors (C or D series) are only occasionally used. In addition, among the restorative materials divided by treatment location such as enamel, dentin, and anterior and posterior teeth, dental restorative materials of less commonly used colors are only occasionally prepared and used.

[0007] This can result in harm to the user, as the product must be discarded after its expiration date. Therefore, uncommon dental restorative materials are less useful to physicians than they are to purchase.

[0008] To solve these problems, Patent Document 1 discloses a method for producing a dental restorative material that can be used universally by manufacturing a restorative material using a group of inorganic spherical particles having a predetermined average primary particle diameter in the range of 100 to 1000 nm and a group of identical spherical particles and a group of ultrafine particles having a refractive index lower than that of a resin matrix.

[0009] However, the nanoparticles used in the above patent have the disadvantage of being expensive due to the difficult manufacturing method and being composed only of small-sized inorganic particles due to the limitations of refractive index, resulting in a weak strength of the restorative material.

[0010] In document 2, a method for manufacturing and using inorganic spherical particles of 1-50 μm using a method developed by our company to overcome the problems of high cost and low strength, a method for manufacturing a dental restorative material that can be used universally is disclosed. Compared to document 1, this method can manufacture spherical particles at a low cost using a relatively inexpensive um particle filler, and has the advantage of high strength due to the use of large spherical particles and a second filler of 1 μm or more without refractive index restrictions. However, this restorative material also has the disadvantage of limited chameleon effect due to low translucency. This limited effect means that colors such as B1 and C1 can be covered with color A1, but other colors such as B2 and C2 cannot be covered.

[0011] Through further research and development, we have developed a universal dental restorative composition that overcomes the aforementioned shortcomings and problems. This disclosure relates to the development of a restorative composition that can be universally used on teeth of various colors, even with a single color.

[0012] <Prior Art Literature>

[0013] 1. Republic of Korea Publication Patent: Publication No. 10-2021-0057026

[0014] 2. Republic of Korea Publication Patent: Publication No. 10-2023-0128855

[0015]

[0016] The technical problem to be achieved by the present invention is to provide a method for manufacturing a dental restorative composition that can be universally used on teeth having various colors even with one color.

[0017]

[0018] The technical problems to be solved by the present invention are not limited to the technical problems mentioned above, and other technical problems not mentioned can be clearly understood by a person having ordinary skill in the technical field to which the present invention belongs from the description below.

[0019]

[0020] In order to achieve the above technical task, the present invention uses a spherical filler in a dental restorative material to control the width of the light refractive index to a low level, thereby inducing a chameleon effect that makes it difficult to distinguish from adjacent teeth, and

[0021] By controlling the content of fillers and pigments that block light transmission within the composition to achieve high translucency, the chameleon effect of the dental restorative composition is maximized, thereby providing a universal dental restorative composition that can be used on teeth of various colors with a single color.

[0022]

[0023] The universal dental restorative composition according to one embodiment of the present invention,

[0024] A first unsaturated double bond compound comprising at least one selected from the group consisting of a monomer having an unsaturated double bond and an oligomer of a monomer having an unsaturated double bond; an organic-inorganic composite filler having a spherical shape with a first average particle diameter (r1); a second filler having a second average particle diameter (r2); and a photoinitiator;

[0025] The second filler may be a universal dental restorative composition having a chameleon effect, characterized in that it has a weight percentage of 40 wt% to 50 wt% relative to the total weight of the universal dental restorative composition.

[0026]

[0027] In addition, according to one embodiment of the present invention, there may be a universal dental restorative composition having a chameleon effect, characterized in that the first average particle diameter is 1 μm to 50 μm.

[0028] In addition, according to one embodiment of the present invention, there may be a universal dental restorative composition having a chameleon effect, characterized in that the second average particle diameter is 1 μm or less.

[0029] In addition, according to one embodiment of the present invention, there may be a universal dental restorative composition having a chameleon effect, characterized in that the organic-inorganic composite filler has a weight percentage of 15 wt% to 40 wt% relative to the total weight of the universal dental restorative composition.

[0030] In addition, according to one embodiment of the present invention, there may be a universal dental restorative composition having a chameleon effect, characterized in that the organic-inorganic composite filler includes a spherical matrix including an organic material; inorganic particles including an inorganic material dispersed on the matrix; and a thermal initiator.

[0031] In addition, according to one embodiment of the present invention, the inorganic material is synthetic amorphous silica, crystalline silica, aluminum oxide, barium aluminosilicate, barium silicate, barium silicate, barium borosilicate, barium fluoroaluminoborosilicate, barium aluminoborosilicate, strontium silicate, strontium borosilicate, strontium aluminoborosilicate, calcium silicate, calcium aluminosilicate, There may be a universal dental restorative composition having a chameleon effect, characterized in that it comprises at least one selected from the group consisting of alumino silicate, silicon nitrides, titanium dioxide, calcium hydroxy apatite, zirconia, and bioactive glass.

[0032]

[0033] In addition, according to one embodiment of the present invention, there may be a universal dental restorative composition having a chameleon effect, characterized in that the organic material includes a second unsaturated double bond compound including at least one selected from the group consisting of a monomer having an unsaturated double bond and an oligomer of a monomer having an unsaturated double bond.

[0034] Additionally, according to one embodiment of the present invention, the second filler,

[0035] Synthetic amorphous silica, crystalline silica, aluminum oxide, barium-aluminosilicate, barium silicate, barium silicate, barium borosilicate, barium fluoroaluminoborosilicate, barium aluminoborosilicate, strontium silicate, strontium borosilicate, strontium aluminoborosilicate, calcium silicate, calcium aluminosilicate, alumino silicate, There may be a universal dental restorative composition having a chameleon effect, characterized in that it comprises at least one selected from the group consisting of silicon nitrides, titanium dioxide, calcium hydroxy apatite, zirconia, and bioactive glass.

[0036] In addition, according to one embodiment of the present invention, the universal dental restorative composition may have a universal dental restorative composition having a chameleon effect, characterized in that the translucency parameter (TP) value is 20 to 25.

[0037]

[0038] In order to achieve the above technical task, another embodiment of the present invention provides a method for manufacturing a universal dental restorative composition.

[0039] The method for manufacturing the universal dental restorative composition according to one embodiment of the present invention is as follows:

[0040] A preparation step of preparing an organic-inorganic composite filler having a spherical shape with a first average particle diameter (r1); and a mixing step of preparing a dental restorative composition by mixing the prepared organic-inorganic composite filler with a second filler having a second average particle diameter (r2) and a photoinitiator; including,

[0041] In the above mixing step, the second filler may have a weight percentage of 40 wt% to 50 wt% relative to the total weight of the general-purpose dental restorative composition, which may be a method for manufacturing a general-purpose dental restorative composition having a chameleon effect.

[0042] In addition, according to one embodiment of the present invention, there may be a method for manufacturing a universal dental restorative composition having a chameleon effect, characterized in that the preparation step includes a dispersion preparation step of dispersing an organic compound, an inorganic compound, and a thermal initiator in a solvent to manufacture a dispersion; and a curing step of thermally curing the manufactured dispersion to manufacture an organic-inorganic composite filler having a spherical shape with a first average particle diameter (r1).

[0043]

[0044] In addition, according to one embodiment of the present invention, there may be a method for manufacturing a universal dental restorative composition having a chameleon effect, characterized in that the first average particle diameter is 1 μm to 50 μm.

[0045] In addition, according to one embodiment of the present invention, there may be a method for manufacturing a universal dental restorative composition having a chameleon effect, characterized in that the second average particle diameter is 1 μm or less.

[0046] In addition, according to one embodiment of the present invention, in the mixing step,

[0047] There may be a method for manufacturing a universal dental restorative composition having a chameleon effect, characterized in that the organic-inorganic composite filler has a weight percentage of 15 wt% to 40 wt% relative to the total weight of the universal dental restorative composition.

[0048]

[0049] According to an embodiment of the present invention, a dental restorative composition can be provided that maximizes the chameleon effect through high translucency while having excellent physical properties, thereby enabling universal use on teeth of various colors with just one color.

[0050]

[0051] The effects of the present invention are not limited to the effects described above, and should be understood to include all effects that can be inferred from the detailed description of the present invention or the composition of the invention described in the claims.

[0052]

[0053] Figure 1 is a schematic diagram showing the form in which light is refracted depending on the type of filler contained in a universal dental restorative composition according to one embodiment of the present invention.

[0054] Figure 2 is a schematic diagram showing the effect of the translucency of a dental restorative composition on the color and chameleon effect of the dental restorative composition.

[0055] Figure 3 is a schematic diagram showing the color tuning potential to explain the chameleon effect.

[0056] Figure 4 is a flow chart showing a flow chart of a method for manufacturing a dental restorative composition.

[0057] Figure 5 is a particle size analysis image of the first organic-inorganic composite filler manufactured in Manufacturing Examples 2.1 to 2.4, respectively.

[0058] Figure 6 is a drawing showing a schematic diagram of the experimental sample of Experimental Example 2.

[0059] Figure 7 is a drawing showing the experimental results of Experimental Example 5.

[0060]

[0061] Hereinafter, the present invention will be described with reference to the attached drawings. However, the present invention may be implemented in various different forms and is not limited to the embodiments described herein. It should be understood that all modifications, equivalents, and alternatives included within the spirit and technical scope of the present invention are included.

[0062] In addition, in order to clearly explain the present invention in the drawings, parts unrelated to the description are omitted, and similar parts are given similar drawing reference numerals throughout the specification.

[0063] Throughout the specification, when a part is said to be "connected (connected, contacted, coupled)" to another part, this includes not only cases where it is "directly connected" but also cases where it is "indirectly connected" with another part in between.

[0064] In addition, when it is said that a part such as a layer, film, region, or plate is “on” another part, this includes not only the case where it is “directly above” the other part, but also the case where there is another part in between. In addition, in the present specification, when it is said that a part such as a layer, film, region, or plate is formed on another part, the direction in which it is formed is not limited to the upper direction, but also includes the case where it is formed in the side or lower direction. Conversely, when it is said that a part such as a layer, film, region, or plate is “under” another part, this includes not only the case where it is “directly below” the other part, but also the case where there is another part in between.

[0065] In this specification, the terms "upper surface" and "lower surface" are used as relative concepts to facilitate understanding of the technical concepts of the present invention. Therefore, "upper surface" and "lower surface" do not refer to specific directions, locations, or components, and are interchangeable.

[0066] For example, 'upper surface' can be interpreted as 'lower surface', and 'lower surface' can be interpreted as 'upper surface'. Accordingly, 'upper surface' can be expressed as 'first' and 'lower surface' can be expressed as 'second', or 'lower surface' can be expressed as 'first' and 'upper surface' can be expressed as 'second'. However, within one embodiment, 'upper surface' and 'lower surface' are not used interchangeably.

[0067] Unless otherwise defined, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. Terms defined in commonly used dictionaries should be interpreted as having a meaning consistent with their meaning in the context of the relevant technology, and shall not be interpreted in an idealized or overly formal sense unless explicitly defined herein.

[0068] Additionally, when a part is said to "include" a component, this does not mean that it excludes other components, but rather that it may include other components, unless otherwise specifically stated.

[0069] The terminology used herein is merely used to describe specific embodiments and is not intended to limit the present invention. The singular expression includes the plural expression unless the context clearly indicates otherwise. In this specification, it should be understood that the terms "comprises" or "has" indicate the presence of a feature, number, step, operation, component, part, or combination thereof described in the specification, but do not exclude in advance the possibility of the presence or addition of one or more other features, numbers, steps, operations, components, parts, or combinations thereof.

[0070]

[0071] As mentioned above, dental restorative materials are used to repair damaged teeth caused by decay or fracture. These materials must possess excellent physical properties. Furthermore, unlike amalgam, modern dental restorative materials must also achieve aesthetic and functional benefits. Since tooth color varies from person to person and tooth type to tooth type, practitioners must select materials that are similar in color to the surrounding teeth.

[0072] Accordingly, in order to solve the above-mentioned conventional technical problems, there is a need for a dental restorative material that has excellent physical properties and can be universally used for various people and various teeth.

[0073] Accordingly, in order to solve the above technical problem, an embodiment of the present invention provides a universal dental restorative composition including a spherical organic-inorganic composite filler with a controlled particle size, and having controlled translucency by controlling the content of fillers and pigments that block light transmission in the composition.

[0074] Hereinafter, embodiments of the present invention will be described in detail with reference to the attached drawings.

[0075] A general purpose dental restorative composition according to one embodiment of the present invention is described.

[0076]

[0077] As an example of the above embodiment, there may be a universal dental restorative composition having a chameleon effect, characterized by including a first unsaturated double bond compound including at least one selected from the group consisting of a monomer having an unsaturated double bond and an oligomer of a monomer having an unsaturated double bond; an organic-inorganic composite filler having a spherical shape with a first average particle diameter (r1); a second filler having a second average particle diameter (r2); and a photoinitiator.

[0078] In the above embodiment, the spherical organic-inorganic composite filler may be a dental restorative material composition characterized by inducing a chameleon effect of the dental restorative material.

[0079] People perceive the shape or color of an object through light reflected or refracted from the object. In general, color is perceived through reflected light with a specific wavelength range, while shape can be perceived through the refracted light itself.

[0080] Also, the more types of light that are refracted and propagate in different directions, the larger the boundary is perceived, whereas the smaller the types of light that are refracted and propagate in different directions, the smaller the boundary is perceived.

[0081] In the case of the above embodiment, by applying a spherical organic-inorganic composite filler to the restorative material using the above principle, the distribution of types of light that are refracted and travel in different directions can be reduced, thereby reducing the aesthetic difference with the surrounding teeth.

[0082]

[0083] Figure 1 is a schematic diagram showing the form in which light is refracted depending on the type of filler contained in a universal dental restorative composition according to one embodiment of the present invention.

[0084]

[0085] Referring to Fig. 1, unlike the case where a single type of filler is simply used as in (a) of Fig. 1, when a spherical filler is used together as in (b) of Fig. 1, it can be confirmed that when light traveling on the restorative material is reflected or refracted, the distribution of types of light traveling in different directions is relatively smaller than when a non-spherical filler is used.

[0086] Additionally, as previously described, people looking at the teeth in Figure 1 may perceive the restorative material as having a similar color to the adjacent teeth when used with a spherical filler.

[0087]

[0088] Furthermore, by using the above-mentioned spherical filler, we can maximize the chameleon effect by controlling the translucency of the dental restorative material with the chameleon effect.

[0089] This principle is implemented as follows: the restorative material applied to a damaged area of ​​a tooth is not reflected solely in its natural color. The color of the restorative material is influenced not only by its natural color but also by the color of the surrounding environment of the restored tooth. The color is perceived through the harmony of these two colors.

[0090] Translucency is the property of a material that allows light to pass through it, thereby allowing the color of the underlying material to affect the color of the material.

[0091] That is, the higher the translucency, the more the color underneath is projected.

[0092]

[0093] Figure 2 is a schematic diagram showing the effect of the translucency of a dental restorative composition on the color and chameleon effect of the dental restorative composition.

[0094]

[0095] Referring to (a) of Fig. 2, it can be confirmed that the color of the teeth located around the restorative material is not sufficiently projected onto the restoration due to low light transmittance in the restorative material with low translucency, and is thus recognized as the color of the restoration.

[0096]

[0097] On the other hand, referring to (b) of Fig. 2, it can be confirmed that a restorative material with high translucency has high light transmittance, so that the color of the teeth located around the restoration is highly projected onto the restorative material, and thus the color of the restorative material can be recognized as the color of the teeth.

[0098]

[0099] By this principle, dental restorative materials with a chameleon effect through spherical fillers maximize the chameleon effect by adjusting the translucency to a high level.

[0100] It is possible to provide a dental restorative material that can be used universally on teeth of various colors, even with just one color.

[0101]

[0102] Figure 3 is a schematic diagram showing the color tuning potential to explain the chameleon effect.

[0103] The above chameleon effect can be expressed using the Color Adjustment Potential (CAP) equation. CAP is an equation for analyzing the chameleon effect, representing the color difference when viewing two colors individually and together.

[0104]

[0105] Referring to Figure 3, the CAP is 1-(ΔE * 2 / ΔE * 1) is calculated as,

[0106] At this time, the above ΔE * 2 represents the color difference between a double composite specimen made of two resins and a single specimen.

[0107] The above ΔE *1 indicates the color difference between two single specimens.

[0108]

[0109] Color difference between a double composite specimen made of two resins and a single specimen (ΔE * 2) The smaller the color difference between the two single specimens (ΔE * 1) The larger it is, the higher the chameleon effect (CAP).

[0110] That is, the closer CAP is to 1, the greater the chameleon effect.

[0111]

[0112] The above “chameleon effect” means an effect in which, when a person independently separates an object such as a restorative material and observes it with the naked eye, the object is recognized as having its own color, but when the restorative material is placed near a tooth or other object, the object such as the restorative material is recognized as having a color similar to that of the nearby object, rather than its own color, making it difficult to recognize the boundary with the naked eye.

[0113]

[0114] Hereinafter, the first unsaturated double bond compound is described.

[0115] The first unsaturated double bond compound may include any one of a monomer having an unsaturated double bond, an oligomer of a monomer having an unsaturated double bond, and a combination thereof.

[0116] In addition, these first unsaturated double bond compounds play a role in forming a matrix within a restorative material when a dental restorative material composition containing a photoinitiator is subjected to light for tooth restoration.

[0117]

[0118] The first unsaturated double bond compound may be, for example, 2,2-bis[4-(2-hydroxy-3-methacryloxypropoxy)phenyl]propane (Bis-GMA), ethylene glycol dimethacrylate (EGDMA), ethylene glycol diacrylate (EDGA), triethylene glycol dimethacrylate (TEGDMA), trimethylopropane trimethacrylate (TMPTMA), triethylene glycol diacrylate (TEGDA), ethoxylated bisphenol A dimethacrylate (Bis-EMA), urethane dimethacrylate (UDMA), polyurethane diacrylate (PUDA), dipentaerythritol pentaacrylate monophosphate (PENTA), 2-hydroxyethyl methacrylate (HEMA), It may include at least one selected from the group consisting of polyalkenoic acid, biphenyl dimethacrylate (BPDM), biphenyl diacrylate (BPDA), and glycerol phosphate dimethacrylate (GPDM).

[0119]

[0120] In addition, it is preferable that the first unsaturated double bond compound has a weight percentage of 5 wt% to 30 wt% relative to the total weight of the general-purpose dental restorative composition.

[0121] At this time, when the first unsaturated double bond compound is less than 5 wt%, a problem occurs in which the amount of the first unsaturated double bond compound is insufficient to sufficiently form a matrix within the restorative material.

[0122] When the amount of the first unsaturated double bond compound exceeds 30 wt%, the amount of the first unsaturated double bond compound becomes excessive, and a problem occurs in which the physical properties deteriorate due to insufficient filler in the matrix.

[0123]

[0124] Hereinafter, an organic-inorganic composite filler having a spherical shape with a first average particle diameter (r1) is described.

[0125] As described above, the dental restorative composition provided by one embodiment of the present invention provides a chameleon effect, and for this purpose, includes an organic-inorganic composite filler having a spherical shape with a first average particle diameter (r1).

[0126]

[0127] As mentioned above, humans have different natural principles of perception when perceiving the shape of an object and when perceiving the color of an object.

[0128] When recognizing a shape, the smaller the distribution of light types that travel in different directions due to reflection or refracted light, the less likely it is that boundaries will be recognized.

[0129] In consideration of this point, by including a spherical organic-inorganic composite filler in the dental restorative composition, when light is reflected or refracted through the boundary of the sphere, the types of light that propagate in different directions can be minimized.

[0130]

[0131] Accordingly, the first average particle size may be larger than that of other fillers added together, preferably, for example, 1 μm to 50 μm, and more preferably, for example, 5 μm to 30 μm.

[0132] At this time, if the particle size is less than 1 μm, a problem occurs where light is not reflected or refracted at the boundary of the organic / inorganic composite filler.

[0133] In cases where the above particle size exceeds 50 μm, there is also a problem that the size of the organic-inorganic composite filler becomes too large, shortening the propagation path of cracks caused by external force, thereby affecting the strength.

[0134] In addition, the above-mentioned organic and inorganic composite filler must play a role in inducing the reflection or refraction of light as described above, and it is important that it be included in an appropriate amount within the entire restorative composition.

[0135] More specifically, it is preferable to have a weight percentage of 15 wt% to 40 wt% relative to the weight of the entire universal dental restorative composition.

[0136]

[0137] In addition, at this time, there may be a universal dental restorative composition having a chameleon effect, characterized in that the organic-inorganic composite filler includes a spherical matrix including an organic material; inorganic particles including an inorganic material dispersed on the matrix; and a thermal initiator.

[0138]

[0139] In this way, by using an organic-inorganic composite filler having the above configuration, it is possible to provide a chameleon effect that makes it impossible to perceive a color difference by lowering the refractive index distribution of reflected light and thereby reducing the aesthetic difference from the surrounding teeth.

[0140]

[0141] At this time, in order to provide a high strength effect, the inorganic material is, for example, synthetic amorphous silica, crystalline silica, barium silicate, barium borosilicate, barium fluoroaluminoborosilicate, barium aluminoborosilicate, strontium silicate, strontium borosilicate, strontium aluminoborosilicate, calcium silicate, calcium aluminosilicate, alumino silicate, silicon nitrides, It may include at least one selected from the group consisting of titanium dioxide, calcium hydroxy apatite, zirconia, and bioactive glass.

[0142]

[0143] In addition, the organic material may include a second unsaturated double bond compound including at least one selected from the group consisting of a monomer having an unsaturated double bond and an oligomer of a monomer having an unsaturated double bond, in order to provide a spherical shape.

[0144]

[0145] More specifically, the organic material is

[0146] 2,2-bis[4-(2-hydroxy-3-methacryloxypropoxy)phenyl]propane (Bis-GMA), ethylene glycol dimethacrylate (EGDMA), ethylene glycol diacrylate (EDGA), triethylene glycol dimethacrylate (TEGDMA), trimethylopropane trimethacrylate (TMPTMA), triethylene glycol diacrylate (TEGDA), ethoxylated bisphenol A dimethacrylate (Bis-EMA), urethane dimethacrylate (UDMA), polyurethane diacrylate (PUDA), dipentaerythritol pentaacrylate monophosphate (PENTA), 2-hydroxyethyl methacrylate (HEMA), polyalkenoic acid, biphenyl dimethacrylate It may include at least one selected from the group consisting of biphenyl diacrylate (BPDA), biphenyl diacrylate (BPDM), and glycerol phosphate dimethacrylate (GPDM).

[0147]

[0148] Below, the second filler of the second average particle diameter (r2) is described.

[0149] A dental restorative composition provided by one embodiment of the present invention includes, in addition to a spherical organic-inorganic composite filler having a controlled particle size, a second filler having a second average particle diameter (r2).

[0150] By further including the second filler, the physical properties of the dental restorative composition can be more firmly secured.

[0151] At this time, it is preferable that the second average particle diameter is 1 μm or less.

[0152] When the above second average particle size exceeds 1 μm, the chameleon effect of the organic-inorganic composite filler in the dental restorative material composition may be inhibited, and at the same time, a problem may occur in which the mechanical properties of the restorative material are lowered.

[0153]

[0154] In addition, the second filler must play a role in allowing the color of the tooth to be sufficiently projected into the restorative material through the aforementioned high translucency, and it is important that it be included in an appropriate amount within the entire restorative material composition.

[0155] It is preferable to have a weight percentage of 40 wt% to 50 wt% relative to the weight of the entire general-purpose dental restorative composition.

[0156] The content of the second filler in the above-mentioned general purpose dental restorative composition affects the permeability of the above-mentioned general purpose dental restorative composition.

[0157] At this time, it is desirable that the transmittance of the dental restorative material be formed at a translucency parameter (TP) value of 20 to 25.

[0158] Referring to Table 4 of Manufacturing Example 3 described below, it can be confirmed that, as an example of the above embodiment, the second filler is contained in an amount of 44.7 wt% with respect to the entire general-purpose dental restorative composition.

[0159] In contrast, in the case of Control Example 1, it can be confirmed that the second filler is contained in an amount of 50 wt% or more with respect to the entire general-purpose dental restorative composition.

[0160]

[0161] Experimental data comparing the above Manufacturing Example 3 and the above Control Example 1 can be confirmed in the following Experimental Example.

[0162] For example, referring to Table 7, compared to B1, the manufacturing example 3 has a very high CAP value of 0.9, while the control example 1 has a CAP value of only 0.72, which is a decrease of 0.18.

[0163] In addition, compared to B2, the above-mentioned Manufacturing Example 3 still has a very high CAP value of 0.85, while the above-mentioned Control Example 1 has a CAP value of only 0.61, confirming that the CAP value has decreased by almost 30% compared to the above-mentioned Manufacturing Example 3.

[0164] In particular, the fact that the CAP value is formed around 0.6 means that a person can easily recognize the difference in color even when looking at it with the naked eye. As described in the background art above, this means that the transparency is insufficient, so the chameleon effect is limited, and when applied to actual teeth, it means that the color such as B2 cannot be completely covered.

[0165] On the other hand, in the case of the above manufacturing example 3, not only B1 but also other colors such as B2 and C2 can be completely covered, so it can be confirmed that one color can be universally used for teeth of various colors.

[0166]

[0167] The difference between the above-mentioned Manufacturing Example 3 and Control Example 1 is caused by the content ratio of the second filler to the overall general-purpose dental restorative composition.

[0168]

[0169] When the second filler is contained in an amount of 50 wt% or more in the above-mentioned general-purpose dental restorative composition, there is a problem in that the transparency is not sufficient, as in the control example 1, so the chameleon effect is limited and it is difficult to apply to various colors.

[0170]

[0171] This can also be confirmed in Table 8 of Experimental Example 3 below.

[0172] When the second filler is contained in an amount of 50 wt% or more in the above-mentioned general-purpose dental restorative composition, it can be confirmed that the translucency parameter (TP) value is only 17, which is insufficient.

[0173] In the case of Manufacturing Example 3, in which the second filler is contained in the range of 40 wt% to 50 wt% in the above-mentioned general-purpose dental restorative composition, it can be confirmed that the composition has sufficient transparency with a translucency parameter (TP) value of 22 or more.

[0174]

[0175] When the translucency parameter (TP) value is less than 20, the transparency is low and the projection of surrounding colors is insufficient. When the translucency parameter (TP) value is more than 25, the transparency is high but the appropriate physical properties of the restorative material are not maintained.

[0176]

[0177] When the second filler has a weight percentage of 40 wt% to 50 wt% relative to the weight of the entire general-purpose dental restorative composition, the translucency parameter (TP) value of the dental restorative composition can be formed in a range of 20 to 25.

[0178] Through this, a high translucency effect can be applied to the above-mentioned general-purpose dental restorative composition.

[0179]

[0180] In addition, the second filler may use a compound containing one or more of the following:

[0181] It may be the same compound as the compound used in the organic-inorganic composite filler, or it may be a different compound.

[0182]

[0183] Such a second filler can be an organic filler, an inorganic filler, or an organic-inorganic composite filler.

[0184] More specifically, the second filler is

[0185] Synthetic amorphous silica, crystalline silica, aluminum oxide, barium-aluminosilicate, barium silicate, barium silicate, barium borosilicate, barium fluoroaluminoborosilicate, barium aluminoborosilicate, strontium silicate, strontium borosilicate, strontium aluminoborosilicate, calcium silicate, calcium aluminosilicate, alumino silicate, There may be a universal dental restorative composition having a chameleon effect, characterized in that it comprises at least one selected from the group consisting of silicon nitrides, titanium dioxide, calcium hydroxy apatite, zirconia, and bioactive glass.

[0186]

[0187] Hereinafter, the above photoinitiator will be described.

[0188] The above photoinitiators are compounds that release initiators that induce a polymerization reaction when irradiated with light. The light used here may be ultraviolet or visible light. A person skilled in the art may use any photoinitiator that can be adopted, and in one specific embodiment, camphorquinone and ethyl 4-(dimethylamino) benzoate were used.

[0189]

[0190] Below, other additives that may be added are described.

[0191] The dental restorative material provided by one embodiment of the present invention may further include other additives. Examples of the other additives that may be included include an antioxidant, a polymerization inhibitor, and the like, and may include one or more of the examples of the other additives, but the present invention is not limited to the examples above.

[0192] In addition, the pigment is a pigment added to make it more similar to various teeth, and various pigments may be added for the convenience of the user. In a specific embodiment of the present invention, titanium oxide was used.

[0193] The above polymerization inhibitor is a compound added to provide an effect of inhibiting unintended polymerization, and a polymerization inhibitor that can be adopted by a technician having ordinary knowledge in the art can be used. In a specific embodiment of the present invention, 2,6-di(tertiary-butyl)-4-methylphenol (BHT) was used.

[0194]

[0195] Hereinafter, the chameleon effect of the above dental restorative composition will be described.

[0196] As mentioned above, the chameleon effect means an effect in which, when a person independently separates a restorative material and observes it with the naked eye, the restorative material is recognized as having its own color, but when the restorative material is placed near a tooth, it is recognized as having a color similar to that of the surrounding area, rather than the restorative material's own color.

[0197]

[0198] At this time, the dental restorative composition preferably has a CAP value of 0.5 to 1 in relation to the target tooth to be restored, more preferably 0.6 to 1, still more preferably 0.7 to 1, and particularly preferably 1.

[0199] In a specific embodiment of the present invention, a restorative composition having a CAP of 0.90 to 0.85 in relation to a reference specimen was prepared, and at this time, it was difficult to visually distinguish it from an adjacent specimen.

[0200]

[0201] Hereinafter, a method for manufacturing a dental restorative composition having a chameleon effect provided by another embodiment of the present invention will be described.

[0202]

[0203] Figure 4 is a flow chart showing a flow chart of a method for manufacturing a dental restorative composition.

[0204] Referring to FIG. 4, another embodiment of the present invention for solving the above technical problem provides a method for manufacturing a universal dental restorative composition having a chameleon effect, characterized by including a preparation step (S100) of preparing an organic-inorganic composite filler having a spherical shape with a first average particle diameter (r1); and a mixing step (S200) of mixing the prepared organic-inorganic composite filler with a second filler having a second average particle diameter (r2) and a photoinitiator to manufacture a dental restorative composition.

[0205]

[0206] Below, the above preparation step (S100) will be described first.

[0207] At this time, the preparation step (S100) may include a dispersion preparation step (S120) of preparing a dispersion by dispersing an organic compound, an inorganic compound, and a thermal initiator in a solvent; and a curing step (S140) of thermally curing the dispersion to prepare an organic-inorganic composite filler having a spherical shape with a first average particle diameter (r1).

[0208] At this time, the dispersion preparation step (S120) may use a dispersion preparation method that can be adopted by a person having ordinary knowledge in the technical field, and in a specific embodiment of the present invention, it was prepared using a stirrer.

[0209] At this time, the organic compound may include at least one unsaturated double bond compound selected from the group consisting of a monomer having an unsaturated double bond and an oligomer of a monomer having an unsaturated double bond, and includes, for example, 2,2-bis[4-(2-hydroxy-3-methacryloxypropoxy)phenyl]propane (Bis-GMA), ethylene glycol dimethacrylate (EGDMA), ethylene glycol diacrylate (EDGA), triethylene glycol dimethacrylate (TEGDMA), trimethylopropane trimethacrylate (TMPTMA), triethylene glycol diacrylate (TEGDA), ethoxylated bisphenol A dimethacrylate (Bis-EMA), urethane dimethacrylate (UDMA), polyurethane diacrylate (PUDA), dipentaerythritol pentaacrylate monophosphate (dipentaerythritol pentaacrylate monophosphate, The polymer may be at least one selected from the group consisting of 2-hydroxyethyl methacrylate (HEMA), polyalkenoic acid, biphenyl dimethacrylate (BPDM), biphenyl diacrylate (BPDA), and glycerol phosphate dimethacrylate (GPDM), but is not limited to the above examples.

[0210] In addition, at this time, the inorganic compound is synthetic amorphous silica, crystalline silica, barium silicate, barium borosilicate, barium fluoroaluminoborosilicate, barium aluminoborosilicate, strontium silicate, strontium borosilicate, strontium aluminoborosilicate, calcium silicate, calcium aluminosilicate, alumino silicate, silicon nitrides, titanium dioxide, It may include at least one selected from the group consisting of calcium hydroxy apatite, zirconia, and bioactive glass.

[0211] At this time, in the thermal curing step (S140), the solvent of the dispersion is evaporated to manufacture a spherical organic-inorganic composite filler. A suitable means that can be selected by a technician with ordinary knowledge in the art can be used. In a specific embodiment of the present invention, a spray dryer was used to thermally cure the dispersion to manufacture a spherical organic-inorganic composite filler.

[0212]

[0213] Hereinafter, the above mixing step (S200) will be described.

[0214] The above mixing step (S200) may further include a first unsaturated double bond compound including at least one selected from the group consisting of a prepared inorganic composite filler, a monomer having an unsaturated double bond, and an oligomer of a monomer having an unsaturated double bond. The description of the first unsaturated double bond compound that can be used in this case is replaced with the description in the above embodiment.

[0215]

[0216] Hereinafter, the present invention will be described in more detail through examples, manufacturing examples, comparative examples, and experimental examples. However, the present invention is not limited to the following examples, manufacturing examples, comparative examples, and experimental examples.

[0217]

[0218] Manufacturing Example 1 - Manufacturing of a Dispersion Composition for Spray Dryer

[0219] In order to manufacture a dental restorative material having a chameleon effect according to one embodiment of the present invention, a dispersion composition for a spray dryer was manufactured.

[0220] In that specific method, barium aluminosilicate was used, UDMA, TEGDMA, and TMPTMA were used as a matrix, ethanol was used as a solvent, and AIBN was used as a polymerization initiator.

[0221] The specific manufacturing ratio is summarized in Table 1 below, and these were manufactured by stirring them at room temperature for 24 hours at a speed of 250 rpm using a stirrer.

[0222] Content (wt%) Manufacturing Example 1.1 Manufacturing Example 1.2 Manufacturing Example 1.3 Manufacturing Example 1.4 UDMA 8 16 8 8 AIBN 0.15 0.15 0.15 0.15 TEGDMA 11 1 1 TM PTMA 11 5 2 barium alumino silicate 5 8 5 0 5 3 5 6 Ethanol 3 1.8 5 3 1.8 5 3 1.8 5 3 1.8 5 3 1.8 5

[0223]

[0224] Manufacturing Example 2 - Manufacturing of a spherical organic-inorganic composite filler

[0225] In this Manufacturing Example 2, a spherical organic-inorganic composite filler was manufactured using the dispersion manufactured through Manufacturing Example 1.

[0226]

[0227] As for the specific manufacturing method,

[0228] A spherical organic-inorganic composite filler was manufactured by thermal curing using a spray dryer, and the organic-inorganic composite fillers of Manufacturing Examples 2.1 to 2.4 in Table 2 below are organic-inorganic composite fillers manufactured using the dispersions of Manufacturing Examples 1.1 to 1.4, respectively.

[0229]

[0230] Spray dryer conditions Manufacturing example 2.1 Manufacturing example 2.2 Manufacturing example 2.3 Manufacturing example 2.4 Inlet temperature (℃) 8 16 8 8 Outlet temperature (℃) 0.15 0.15 0.15 0.15 Air flow (L / min) 11 11 Pump speed (rpm) 11 5 2

[0231]

[0232] Experimental Example 1 - Particle size analysis of a spherical organic-inorganic composite filler

[0233] In this Experimental Example 1, the physical properties of spherical organic-inorganic composite fillers manufactured through the above Manufacturing Example 2 were investigated.

[0234] The experimental method and results of Experimental Example 1 are summarized in Table 3 below.

[0235]

[0236] Spray dryer conditions Manufacturing example 2.1 Manufacturing example 2.2 Manufacturing example 2.3 Manufacturing example 2.4 Inlet temperature (℃) 100 100 100 100 Outlet temperature (℃) 75 75 75 75 Air flow (L / min) 26 26 26 26 Pump speed (rpm) 20 20 20 20 Particle size analysis results Mean diameter (um) (after #325 mesh) 15.5 7 10.9 7 21.4 9 9.96 Yield (%) 7 26 36 564

[0237]

[0238] Figure 5 is a particle size analysis image of the first organic-inorganic composite filler manufactured in Manufacturing Examples 2.1 to 2.4, respectively.

[0239] Referring to Table 3 and Figure 5 above, it can be confirmed that the organic / inorganic composite filler is manufactured with an average diameter of about 10 μm to 21 μm and is well formed into a spherical shape.

[0240] Additionally, it can be seen that the composition showing the highest yield is Manufacturing Example 1.1.

[0241]

[0242] Manufacturing Example 3 - Manufacturing of dental restorative material using the organic-inorganic composite filler of Manufacturing Example 2.1

[0243] In this Manufacturing Example 3, a dental restorative composition was manufactured using the spherical organic-inorganic composite filler manufactured in Manufacturing Example 2.1.

[0244] The specific composition ratios are summarized in Table 4 below, and Table 4 also provides comparative examples of conventional dental restorative compositions.

[0245] Comparative Example 1 is a restorative composition manufactured only with inorganic particles, and Control Example 1 is a restorative composition manufactured with spherical particles of 1 to 50 μm as mentioned in Document 2 and about 55% of inorganic particles as a second filler. Manufacturing Example 3 is a restorative composition having high translucency, manufactured with spherical particles of 1 to 50 μm and about 45% of inorganic particles as a second filler as a composition of the present invention.

[0246]

[0247] Manufacturing Example 3 Comparative Example 1 Comparative Example 1 Bis-GMA 15.0 15.0 15.0 UDMA 2.6 2.6 2.6 barium aluminosilicate 44.75 4.77 3.4 CQ 0.04 0.04 0.04 ED 0.10.10.1 BHT 0.10.10.1 Trace amount of pigment and fluorescent agent Manufacturing Example 2.1 Spherical organic-inorganic composite filler 27.5 27.5 - Color Universal A1 A1 Characteristics High translucency Spherical filler applied Low translucency Spherical filler applied Low translucency Spherical filler not applied

[0248]

[0249] Experimental Example 2 - Colorimetric Analysis of the Chameleon Effect

[0250] In this Experimental Example 2, a colorimetric analysis was conducted on the chameleon effect of Manufacturing Example 3, Control Example 1, and Comparative Example 1 described in Table 4 above.

[0251]

[0252] In order to conduct this colorimetric analysis, single and composite specimens were prepared as summarized in Table 5 below, and the colorimetric results for these specimens are summarized in Table 5 below.

[0253]

[0254] Entry Sample Shade Black Figure Lab 1 Control - DenFil NB 1 70.81-1.9 1.77 Single specimen (Fig. 6 a) 2 Manufacturing Example 3 Universal 6 0.22-0.46 0.87 3 Control Example 1 A 1 65.49 0.21-0.46 4 Comparative Example 1 A 1 70.41-2.16-0.085 Control - DenFil NB 2 69.33-1.3 16.34 6 External - Denfil N (B1) Internal - Manufacturing Example 3 (Universal) Universal in B 1 69.83-1.5 6 1.68 Composite specimen (Fig. 6 b) 7 External - Denfil N (B1) Internal - Control Example 1 (A1) A1 in B 1 69.41-0.93 1.858 External - Denfil N (B1) Internal - Comparative Example 1 (A1) A1 in B1 71.62-2.10.969 External - Denfil N (B2) Internal - Manufacturing 3 (Universal) Universal in B2 68.72-0.984.89 10 External - Denfil N (B2) Internal - Control Example 1 (A1) A1 in B2 68.13-0.573.58 11 External - Denfil N (B2) Internal - Comparative Example 1 (A1) A1 in B2 71.94-1.032.29

[0255]

[0256] Figure 6 is a drawing showing a schematic diagram of an experimental sample of Experimental Example 2.

[0257]

[0258] Referring to Fig. 6 and Table 5 above, the single specimen was made with a diameter of 10 mm and a thickness of 4 mm, and the composite specimen (double composite specimen) was made with an outer diameter of 10 mm and a thickness of 4 mm, and an inner hole with a diameter of 4 mm and a thickness of 2 mm. At this time, the outer side was filled with B1 or B2 of DenFil N, and the inner side was filled with Manufacturing Example 3, Control Example 1, and Comparative Example 1.

[0259]

[0260] At this time, L, a, and b represent brightness, red to green, and yellow to blue, respectively, and measurements were conducted using a spectrophotometer in reflection mode and a black white board.

[0261]

[0262] EntryΔE2ΔE1Comparison numberComparison groupA-10.73Color difference between entries 1 and 2Color difference between single specimen of Control DenFil N (B1) and single specimen of manufacturing example 3 universalB-6.14Color difference between entries 1 and 3Color difference between single specimen of Control DenFil N (B1) and single specimen of control example 1 (A1)C-1.91Color difference between entries 1 and 4Color difference between single specimen of Control DenFil N (B1) and single specimen of comparison example 1 (A1)D-10.66Color difference between entries 5 and 2Color difference between single specimen of Control DenFil N (B2) and single specimen of manufacturing example 3 universalE-7.96Color difference between entries 5 and 3Color difference between single specimen of Control DenFil N (B2) and single specimen of control example 1 (A1)F-6.57Color difference between entries 5 and 4Control Color difference between a single specimen of DenFil N (B2) and a single specimen of Comparative Example 1 (A1) G1.04 - Color difference between Entries 1 and 6 Color difference between a single specimen of Control DenFil N (B1) and a composite specimen (outside - Denfil N (B1) / inside - Manufacturing Example 3 (Universal)) H1.71 - Color difference between Entries 1 and 7 Color difference between a single specimen of Control DenFil N (B1) and a composite specimen (outside - Denfil N (B1) / inside - Control Example 1 (A1) I1.16 - Color difference between Entries 1 and 8 Color difference between a single specimen of Control DenFil N (B1) and a composite specimen (outside - Denfil N (B1) / inside - Comparative Example 1 (A1) J1.61 - Color difference between Entries 5 and 9 - Color difference of Manufacturing Example 3 (Universal)) K3.10 - Color difference of Entry 5 and 10 Control DenFil N (B2) single specimen and composite specimen (outer - Denfil N (B1) / inner - Control Example 1 (A1) Color difference L4.83-Color difference between Entry 5 and 11 Control DenFil N (B2) single specimen and composite specimen (outer - Denfil N (B1) / inner - Comparative Example 1 (A1).

[0263]

[0264] Table 6 above is organized based on the data in Table 5 above, and was calculated according to the following formula.

[0265]

[0266] ΔE1 (color difference between single specimen and control single specimen):

[0267] - L c , a c , b c : L, a, b values ​​of Control DenFil N single specimen (B1 or B2)

[0268] - L x , a x , b x : L, a, b values ​​of single specimens

[0269]

[0270] ΔE2 (color difference between double composite specimen and control single specimen):

[0271] - L c , a c , b c : L, a, b values ​​of Control DenFil N single specimen (B1 or B2)

[0272] - L dx , a dx , b dx : L, a, b values ​​of double composite specimens

[0273]

[0274] Experimental Example 3 - Confirmation of CAP Results

[0275]

[0276] In this Experimental Example 3, an experiment was conducted to confirm the CAP of Manufacturing Example 3, Control Example 1, and Comparative Example 1 based on the experimental results of Experiment 2 above.

[0277]

[0278] The results are as shown in Table 7 below.

[0279]

[0280] Comparison group Comparison number △E2△E1 CAP= 1-(△E2 / △E1) Control DenFil N (B1) and Manufacturing Example 3 (Universal) Entry A and G1.0410.730.90 Control DenFil N (B1) and Control Example 1 Entry B and H1.716.140.72 Control DenFil N (B1) and Comparative Example 1 Entry C and I1.161.910.39 Control DenFil N (B2) and Manufacturing Example 3 (Universal) Entry D and J1.6110.660.85 Control DenFil N (B2) and Control Example 1 Entry E and K3.107.960.61 Control DenFil N (B2) and Comparative Example 1 Entry F and L4.836.570.26

[0281]

[0282] Referring to Table 7 above, in the DenFil N (B1) color, the above manufacturing example 3 has a very high CAP value of 0.9, whereas

[0283] The above comparative example 1 has an extremely low CAP value of 0.39,

[0284] The CAP value of the above control example 1 is also only 0.72, and it can be confirmed that the CAP value is lower by 0.18 compared to the above manufacturing example 3.

[0285] Also, in the DenFil N (B2) color, the above manufacturing example 3 still has a very high CAP value of 0.85,

[0286] The above comparative example 1 has an extremely low CAP value of 0.26.

[0287] The above control example 1 has a CAP value of only 0.61, and it can be confirmed that the CAP value is reduced by approximately 30% compared to the above manufacturing example 3.

[0288] In particular, the fact that the CAP value is formed around 0.6 means that a person can easily recognize the difference in color even when looking at it with the naked eye. As described in the background art above, this means that the transparency is insufficient, so the chameleon effect is limited, and when applied to actual teeth, it means that the color such as B2 cannot be completely covered.

[0289] On the other hand, in the case of the above manufacturing example 3, not only B1 but also other colors such as B2 and C2 can be completely covered, so it can be confirmed that one color can be universally used for teeth of various colors.

[0290]

[0291] The above results are evidence that the chameleon effect was maximized due to the previously mentioned spherical filler and high translucency.

[0292] Comparative Example 1, to which a spherical filler was applied, had a higher CAP than Comparative Example 1, to which a spherical filler was not applied.

[0293] The reason why Manufacturing Example 3, which applied high translucency by lowering the content of the second filler to 50 wt% or less while applying the old filler, has a higher CAP than Control Example 1 is this.

[0294]

[0295] Table 8 below shows the translucency results of the samples from Experimental Example 3. Translucency can be expressed as a value called TP (translucency parameter) using the following equation. TP is calculated by measuring the color of a specimen of a certain thickness on a white background and a black background, and then expressing the difference between the two measurements as a numerical value.

[0296] As can be seen in Table 8 below, the TP value of Manufacturing Example 3 is the highest. This means that Manufacturing Example 3 has the highest translucency effect compared to Control Example 1 or Comparative Example 1.

[0297]

[0298] Sample Shade BlackWhiteTPLabLabManufacturing Example 3Universal63.22-2.46-6.683.29-1.173.8522.664Control Example 1A169.77-0.560.783.811.6910.5717.309Comparative Example 1A169.62-0.797.180.74.1421.2418.628

[0299]

[0300] Measurements were conducted using black and white boards in the above L, a, and b reflection modes.

[0301] The TP value was calculated as the color difference of L, a, and b between Black and White, as follows.

[0302]

[0303] TP =

[0304]

[0305] L b , a b , b b : L, a, b values ​​measured in black reflection mode

[0306] L w , a w , b w : L, a, b values ​​measured in white reflection mode

[0307]

[0308] Experimental Example 4 - Confirmation of Physical Properties as a Dental Restorative Material

[0309]

[0310] In this Experimental Example 4, the physical properties of the dental restorative materials manufactured in Manufacturing Example 3 to Control Example 1 and the existing product of the company, DenFil N, were compared and analyzed.

[0311] The experimental results for this are as described in Table 9 below.

[0312] The specific test method was conducted according to ISO 4049:2019.

[0313]

[0314] Test Item Standard Manufacturing Example 3 Control Example 1 DenFil N (A3) Flexural strength (MPa) > 100 1 10.53 (7.61) 115.87 (12.24) 116.91 (3.291) Polymerization depth (mm) > 1.5 2.830 (0.024) 2.320 (0.029) 2.433 (0.017) Light sensitivity Must maintain a homogeneous state. Maintain a homogeneous state. Maintain a homogeneous state. Maintain a homogeneous state. Maintain a homogeneous state. Color stability Matches the color sample and there should be no color change. Matches the color sample and there is no color change. Matches the color sample and there is no color change. Matches the color sample and there is no color change. Water absorption (㎍ / ㎣) < 40 17.6 16.8 19 Water solubility (㎍ / ㎣) < 7.5 1.3 1.3 0.1

[0315]

[0316] Referring to Table 9 above, it can be seen that Manufacturing Example 3 to Control Example 1 do not impair the properties when compared to the properties of conventional dental restorative materials.

[0317] Therefore, it can be seen that the dental restorative material of Manufacturing Example 3 of the present invention has a maximized chameleon effect while maintaining the physical properties of the restorative material.

[0318]

[0319] Experimental Example 5 - Comparison photos after applying dental restorative material to teeth.

[0320]

[0321] In this Experimental Example 5, the results of an experiment were shown in which a dental restorative material was applied to a tooth and the color difference was confirmed with the naked eye.

[0322] Figure 7 is a drawing showing the experimental results of Experimental Example 5.

[0323]

[0324] Figures 7 (a) and 7 (d) are drawings showing the results of an experiment applied to teeth made of DenFil N B1 and B2, respectively, for Manufacturing Example 3.

[0325] Figures 7 (b) and 7 (e) are drawings showing the results of an experiment in which Control Example 1 was applied to teeth made of DenFil N's B1 and B2, respectively.

[0326] Figures 7(c) and 7(f) are drawings showing the results of an experiment in which Comparative Example 1 was applied to teeth made of DenFil N's B1 and B2, respectively.

[0327]

[0328] Referring to Fig. 7 of the above Experimental Example 5, Comparative Example 1 (A1) to which no spherical filler was applied showed a clear difference when applied to teeth B1 and B2, and could be distinguished with the naked eye.

[0329] Control example 1 (A1) with a spherical filler applied is not clearly distinguishable with the naked eye in B1, but can be seen to be distinguishable in the teeth of B2.

[0330] On the other hand, in Manufacturing Example 3 (Universal), in which a high translucency effect was applied by applying a spherical inorganic composite filler and simultaneously lowering the content of the second filler to 50 wt% or less, it was confirmed that the difference could not be discerned with the naked eye when applied to teeth composed of B1 and B2 of DenFil N.

[0331] Accordingly, it can be confirmed that Manufacturing Example 3 has a maximized chameleon effect compared to Comparative Example 1 or Control Example 2.

[0332]

[0333] The foregoing description of the present invention is for illustrative purposes only, and those skilled in the art will readily appreciate that the present invention can be readily modified into other specific forms without altering the technical spirit or essential characteristics of the present invention. Therefore, the embodiments described above should be understood as illustrative in all respects and not restrictive. For example, each component described as a single entity may be implemented in a distributed manner, and similarly, components described as distributed may be implemented in a combined manner.

[0334] The scope of the present invention is indicated by the claims described below, and all changes or modifications derived from the meaning and scope of the claims and their equivalent concepts should be interpreted as being included in the scope of the present invention.

Claims

1. A first unsaturated double bond compound comprising at least one selected from the group consisting of a monomer having an unsaturated double bond and an oligomer of a monomer having an unsaturated double bond; The first average particle diameter (r 1 ) Organic and inorganic composite filler having a spherical shape; Second average particle diameter (r) 2 ) a second filler; and Including photoinitiators; A universal dental restorative composition having a chameleon effect, characterized in that the second filler has a weight percentage of 40 wt% to 50 wt% relative to the total weight of the universal dental restorative composition.

2. In paragraph 1, A universal dental restorative composition having a chameleon effect, characterized in that the first average particle diameter is 1 μm to 50 μm.

3. In paragraph 1, A universal dental restorative composition having a chameleon effect, characterized in that the second average particle diameter is 1 μm or less.

4. In paragraph 1, A universal dental restorative composition having a chameleon effect, characterized in that the organic / inorganic composite filler has a weight percentage of 15 wt% to 40 wt% relative to the total weight of the universal dental restorative composition.

5. In paragraph 1, the organic / inorganic composite filler, A spherical matrix containing organic matter; Inorganic particles containing an inorganic substance dispersed on the above matrix; and A universal dental restorative composition having a chameleon effect, characterized by comprising a thermal initiator.

6. In paragraph 5, the inorganic material is, Synthetic amorphous silica, crystalline silica, aluminum oxide, barium aluminosilicate, barium silicate, barium silicate, barium borosilicate, barium fluoroaluminoborosilicate, barium aluminoborosilicate, strontium silicate, strontium borosilicate, strontium aluminoborosilicate, calcium silicate, calcium aluminosilicate, alumino silicate, A universal dental restorative composition having a chameleon effect, characterized in that it comprises at least one selected from the group consisting of silicon nitrides, titanium dioxide, calcium hydroxy apatite, zirconia, and bioactive glass.

7. In paragraph 5, A universal dental restorative composition having a chameleon effect, characterized in that the organic material comprises a second unsaturated double bond compound including at least one selected from the group consisting of a monomer having an unsaturated double bond and an oligomer of a monomer having an unsaturated double bond.

8. In the first paragraph, the second filler, Synthetic amorphous silica, crystalline silica, aluminum oxide, barium aluminosilicate, barium silicate, barium silicate, barium borosilicate, barium fluoroaluminoborosilicate, barium aluminoborosilicate, strontium silicate, strontium borosilicate, strontium aluminoborosilicate, calcium silicate, calcium aluminosilicate, alumino silicate, A universal dental restorative composition having a chameleon effect, characterized in that it comprises at least one selected from the group consisting of silicon nitrides, titanium dioxide, calcium hydroxy apatite, zirconia, and bioactive glass.

9. In the first paragraph, the general purpose dental restorative composition, A universal dental restorative composition having a chameleon effect, characterized in that the translucency parameter (TP) value is 20 to 25.

10. First average particle diameter (r) 1 ) Preparatory step of preparing an organic / inorganic composite filler having a spherical shape; and The above-mentioned prepared organic and inorganic composite filler has a second average particle size (r 2 ) and a second filler, and a photoinitiator to prepare a dental restorative composition; including a mixing step; A method for producing a universal dental restorative composition having a chameleon effect, characterized in that in the mixing step, the second filler has a weight percentage of 40 wt% to 50 wt% relative to the total weight of the universal dental restorative composition.

11. In paragraph 10, the preparation step is: A dispersion preparation step for preparing a dispersion by dispersing an organic compound, an inorganic compound, and a thermal initiator in a solvent; and The dispersion prepared above is heat-cured to obtain the first average particle size (r 1 ) A method for producing a universal dental restorative composition having a chameleon effect, characterized by including a curing step of producing an inorganic composite filler having a spherical shape.

12. In paragraph 10, A method for manufacturing a universal dental restorative composition having a chameleon effect, characterized in that the first average particle diameter is 1 μm to 50 μm.

13. In paragraph 10, A method for manufacturing a universal dental restorative composition having a chameleon effect, characterized in that the second average particle diameter is 1 μm or less.

14. In the 10th paragraph, in the mixing step, A method for manufacturing a universal dental restorative composition having a chameleon effect, characterized in that the organic / inorganic composite filler has a weight percentage of 15 wt% to 40 wt% relative to the total weight of the universal dental restorative composition.

Images