Metal oxide dispersion composition

Abstract

The present invention provides a metal oxide dispersion composition which is excellent in terms of long-term stability and being free from stickiness, and having good usability.　This metal oxide dispersion composition contains the following components (A)-(C): (A) a polyhydroxystearic acid; (B) a silicone-treated metal oxide; and (C) glyceryl oleate. The metal oxide of the component (B) is a metal oxide other than titanium oxide.

Description

Metal oxide dispersion composition

[0001] The present invention relates to a metal oxide dispersion composition, and more particularly to a metal oxide dispersion composition that is stable over time, non-sticky, and easy to use.

[0002] Metal oxides contained in cosmetics, paints, etc. are used as raw materials with various functions. In particular, these metal oxides have the characteristic that they can achieve various effects depending on the size (average particle diameter). Metal oxides with a large average particle diameter are sometimes used as white pigments as colorants, while metal oxides with a small average particle diameter have excellent UV protection properties and are used in sunscreen cosmetics, etc. However, the smaller the average particle diameter, the worse the dispersibility in the composition tends to be, and the more likely the metal oxides are to form aggregates.

[0003] To solve these problems, techniques have been proposed for improving dispersibility by increasing the hydrophobicity of metal oxides through surface treatment, such as a technique for improving dispersibility by surface treatment with a compound that is solid and liquid at room temperature (see, for example, Patent Document 1), and a technique for improving dispersibility by surface treatment with alkylalkoxysilane (see Patent Document 2).

[0004] JP 2001-72527 A JP 8-119832 A

[0005] However, the technology of Patent Document 1 suffers from the problem that the surface treatment of a solid compound results in a lack of smoothness and poor spreadability when applied to the skin. The technology of Patent Document 2 suffers from the problem that a large amount of silicone oil must be contained in the oil phase, making it difficult to contain oils with poor compatibility, such as solid UV absorbers, and therefore limits the range of formulation. Furthermore, the technologies of Patent Documents 1 and 2 are concerned about gelation over time, and therefore it has not been possible to obtain a composition that does not gel over time, has excellent stability over time, is non-sticky, and has good usability. The metal oxide dispersion composition of the present invention has excellent stability over time, is non-sticky, and has good usability.

[0006] In view of these circumstances, the present inventors have conducted extensive research to solve the above problems, and as a result have found that a metal oxide dispersion composition that is stable over time and has excellent non-stickiness can be obtained by using a combination of a silicone-treated metal oxide, polyhydroxystearic acid, and glyceryl oleate, thereby completing the present invention.

[0007] That is, the present invention provides a metal oxide dispersion composition containing the following components (A) to (C): (A) polyhydroxystearic acid, (B) a silicone-treated metal oxide, and (C) glyceryl oleate, wherein the metal oxide of component (B) is a metal oxide other than titanium oxide. The mass ratio (B) / {(A)+(C)} of component (B) to the total content of components (A) and (C) may be less than 12. Component (B) may be a dimethylpolysiloxane-treated metal oxide. The content of component (B) may be 20 to 80 mass%. The mass ratio (B) / (C) of component (B) to component (C) may be 1 to 30. The mass ratio (A) / (C) of component (A) to component (C) may be 0.1 to 3.0. The metal oxide of component (B) may be zinc oxide. The metal oxide dispersion composition may further contain a polyhydric alcohol as component (D). The present invention also provides a cosmetic or topical skin preparation containing the metal oxide dispersion composition. The cosmetic or topical skin preparation may be an oil-in-water emulsion. The cosmetic or topical skin preparation may be used for sunscreen purposes. The present invention also provides a cosmetic or topical skin preparation containing the following components (A) to (C): (A) polyhydroxystearic acid, (B) a silicone-treated metal oxide, and (C) glyceryl oleate, wherein the metal oxide of component (B) is a metal oxide other than titanium oxide. In the cosmetic or topical skin preparation, the mass ratio (B) / {(A)+(C)} of component (B) to the total content of components (A) and (C) may be less than 12. In the cosmetic or topical skin preparation, component (B) may be a dimethylpolysiloxane-treated metal oxide. In the cosmetic or topical skin preparation, the content of the component (B) may be 1 to 35% by mass. In the cosmetic or topical skin preparation, the mass ratio (B) / (C) of the component (B) to the component (C) may be 1 to 30. In the cosmetic or topical skin preparation, the mass ratio (A) / (C) of the component (A) to the component (C) may be 0.1 to 3.0. In the cosmetic or topical skin preparation, the metal oxide of the component (B) may be zinc oxide.The cosmetic or topical skin preparation may further contain a component (D) polyhydric alcohol. In the cosmetic or topical skin preparation, the component (D) may be glycerin. The cosmetic or topical skin preparation may be an oil-in-water emulsion. The cosmetic or topical skin preparation may be used as a sunscreen.

[0008] The metal oxide dispersion composition of the present invention has excellent stability over time, excellent non-stickiness, and good usability. Furthermore, by using a combination of component (A) polyhydroxystearic acid and component (C) glyceryl oleate, the metal oxide dispersion composition of the present invention can be made to have excellent stability over time, excellent non-stickiness, and good usability, even when using a silicone-treated metal oxide that is surface-treated by physical adsorption, which has a weaker adsorption force than that by chemical adsorption.

[0009] 1 shows photographs of the appearance of the oil-in-water emulsion cosmetics of Example 8 (left) and Comparative Example 6 (right).

[0010] The present invention will be described in detail below. In this specification, "to" means a range including the numerical values ​​before and after it. Furthermore, numerical values ​​expressed as % are values ​​based on mass unless otherwise specified. Note that the embodiments described below are representative embodiments of the present invention, and the scope of the present invention is not limited to these embodiments.

[0011] The present invention will be described in the following order: 1. First embodiment (1) Structure of metal oxide dispersion composition (2) Components (3) Method for producing metal oxide dispersion composition (4) Uses 2. Second embodiment (1) Structure of cosmetic preparation (2) Components (3) Method for producing cosmetic preparation (4) Uses 3. Third embodiment (1) Structure of topical skin preparation (2) Components (3) Method for producing topical skin preparation (4) Uses 4. Fourth embodiment (1) Structure of cosmetic preparation (2) Components (3) Method for producing cosmetic preparation (4) Uses 5. Fifth embodiment (1) Structure of topical skin preparation (2) Components (3) Method for producing topical skin preparation (4) Uses 6. Examples

[0012] In this specification, unless a measurement environment is specifically stated in connection with the explanation of the measurement method, the measurement is performed in an environment of 25°C ± 2°C and 50% RH ± 5% RH.

[0013] 1. First embodiment

[0014] (1) Constitution of Metal Oxide Dispersion Composition The metal oxide dispersion composition of this embodiment contains component (A) polyhydroxystearic acid, component (B) silicone-treated metal oxide, and component (C) glyceryl oleate, and the metal oxide of component (B) is a metal oxide other than titanium oxide. Each component constituting the metal oxide dispersion composition will be described below.

[0015] (2) Each component

[0016] A. [Component (A) Polyhydroxystearic Acid] Component (A) polyhydroxystearic acid in this embodiment is a polymer of hydroxystearic acid having a hydroxyl group. Component (A) polyhydroxystearic acid is used to disperse component (B) silicone-treated metal oxide, and the hydroxyl group of the hydroxystearic acid is preferably at the 12-position, and the degree of polymerization of the hydroxystearic acid is preferably 3 to 12, and more preferably 4 to 8. Commercially available products include Salacos HS-6C (manufactured by The Nisshin Oillio Group, Ltd.) and ARLACEL P-100 (manufactured by Uniqema).

[0017] B. [Component (B): Silicone-Treated Metal Oxide] In the silicone-treated metal oxide component (B) of this embodiment, the metal oxide is a metal oxide, excluding titanium oxide, that blocks ultraviolet light over a wide range from UVB to UVA (290 to 400 nm) by absorbing, scattering, reflecting, quenching, or the like, and is not particularly limited as long as it is a metal oxide commonly used in cosmetics, quasi-drugs, pharmaceuticals, etc. As the metal oxide, one or more selected from the group consisting of zinc oxide, cerium oxide, iron oxide, and chromium oxide can be preferably used in view of ease of commercial availability. From the viewpoint of ultraviolet protection effect, etc., one or more selected from the group consisting of zinc oxide and cerium oxide can be more preferably used, with zinc oxide being particularly preferred. Furthermore, the metal oxide can contain trace elements with a valence of +2 or higher, and metals such as iron, zirconium, calcium, manganese, magnesium, and yttrium can be contained in the metal oxide alone or in appropriate combinations of two or more.

[0018] The particle size of the metal oxide is not particularly limited, but from the viewpoint of ultraviolet protection effect, the average particle size is preferably 1 nm to 1 μm, more preferably 3 nm to 100 nm, and even more preferably 5 nm to 50 nm.

[0019] In this embodiment, the average particle size can be measured by image analysis of a transmission electron microscope image. A method for measuring the average particle size will be described below.

[0020] Approximately 10 mg of sample is thoroughly dispersed in 1-propanol on a glass slide to obtain a dispersion. The dispersion is stretched to obtain a thin film sample. The thin film of the sample is placed on a transmission electron microscope (TEM) measurement mesh with a support film attached. The mesh (dried coating film) is set in a transmission electron microscope (S-4800, Hitachi High-Technologies Corporation) and observed, obtaining an image of the dried coating film showing individual particles. The image of this dried coating film surface is processed using an image analysis particle size distribution analyzer (Mac-View, Mountec Co., Ltd.) with 1,000 particles measured, and the particle size is measured. This allows the average particle size D50 of the sample (powder) to be obtained by image analysis of the transmission electron microscope (TEM) image.

[0021] The shape of the metal oxide is not particularly limited, but examples thereof include granular, spherical, plate-like, spindle-like, dendritic, and balloon-like shapes. From the viewpoint of ultraviolet protection effect, etc., granular, spherical, plate-like, and spindle-like shapes are preferred.

[0022] The metal oxide is not particularly limited, and examples of commercially available zinc oxide include FINEX-25 (manufactured by Sakai Chemical Industry Co., Ltd.), FINEX-50 (manufactured by Sakai Chemical Industry Co., Ltd.), FINEX-75 (manufactured by Sakai Chemical Industry Co., Ltd.), MZ300 series (manufactured by Teika Corporation), MZ500 series (manufactured by Teika Corporation), MZ700 series (manufactured by Teika Corporation), and ZnO-350 (manufactured by Sumitomo Osaka Cement Co., Ltd.). Examples of cerium oxide include high-purity cerium sold by Nikki Co., Ltd. or Seimi Chemical Co., Ltd.

[0023] The silicone-treated metal oxide can be obtained by subjecting the metal oxide to a silicone treatment. Examples of such silicone treatments include treatments using a silicone treatment agent. Examples of the silicone treatment agent include linear silicones such as low-polymerization dimethylpolysiloxane, high-polymerization dimethylpolysiloxane, and methylphenylpolysiloxane; modified silicones such as amino-modified silicone, alkyl-modified silicone, and alkoxy-modified silicone; silicone resins such as trimethylsiloxysilicate and acrylic-silicone graft copolymer; silicone rubbers; partially or fully crosslinked organopolysiloxanes; silylating agents; and silane coupling agents. One or more selected from the group consisting of these may be used. In this embodiment, a silicone treatment using physical adsorption, which has a weaker adsorption force than chemical adsorption, is preferred, and dimethylpolysiloxane is more preferred.

[0024] The silicone treatment method is not particularly limited, and can be performed by a commonly known method. For example, a silicone treatment agent and powder metal oxide particles to be treated are added to a solvent, stirred in a ball mill or the like, dried as necessary, washed with water, and filtered repeatedly to remove impurities, and then dried and pulverized to obtain the desired silicone-treated metal oxide powder. It is also possible to simultaneously silicone-treat several types of metal oxides, or to silicone-treat one metal oxide first and then silicone-treat another metal oxide. The amount of silicone treatment agent relative to the metal oxide is not particularly limited, but is preferably 40% or less, more preferably 2 to 35%.

[0025] C. [Component (C) Glyceryl Oleate] In this embodiment, the component (C) glyceryl oleate can be one or more selected from the group consisting of glyceryl monooleate, glyceryl dioleate, and glyceryl trioleate. In particular, the glyceryl oleate preferably includes glyceryl monooleate, and more preferably is glyceryl monooleate.

[0026] The glyceryl oleate is not particularly limited, and examples thereof include NIKKOL MGO (product name, manufactured by Nikko Chemical Co., Ltd.) and Glymoist MO (manufactured by NOF Corporation) that are commercially available.

[0027] D. [Component (D) Polyhydric Alcohol] The metal oxide dispersion composition of the present embodiment may further contain component (D) polyhydric alcohol. Such polyhydric alcohols are not particularly limited, but include glyceryl, glycerin, 1,3-butylene glycol, dipropylene glycol, tripropylene glycol, as well as sugar alcohols such as sorbitol and mannitol. Glyceryl is particularly preferred as such a polyhydric alcohol.

[0028] E. [Other Components] In addition to the above-described components, the metal oxide dispersion composition of this embodiment may contain other powders, surfactants, oils, gelling agents, antioxidants, preservatives, colorants, fragrances, cosmetic ingredients, and the like, depending on the purpose, within quantitative and qualitative ranges that do not impair the effects of this embodiment. Details will be described in the second embodiment.

[0029] The metal oxide dispersion composition of this embodiment is preferably an oil-based dispersion in which a powder is dispersed in an oil. The dispersion medium is not particularly limited as long as it is an oil that is liquid at 25°C, but is preferably an ester oil. Details will be described in the second embodiment. The content of the dispersion medium is not particularly limited, but is preferably 5 to 70 mass% (hereinafter abbreviated as "%") in the composition, more preferably 10 to 60%, even more preferably 15 to 60%, and particularly preferably 15 to 50%. Here, "liquid at 25°C" means that the dispersion medium has fluidity at 25°C.

[0030] In this embodiment, the content of component (A) is preferably 1 to 15% by mass (hereinafter abbreviated as "%"), more preferably 2 to 10%, even more preferably 2 to 9%, even more preferably 3 to 9%, and particularly preferably 4 to 9%. Within this range, better stability over time and good usability without stickiness can be achieved.

[0031] In this embodiment, the mass ratio (B) / {(A)+(C)} of the component (B) to the total content of the components (A) and (C) is preferably less than 12, more preferably 10 or less, even more preferably 9 or less, even more preferably 8 or less, particularly preferably 7 or less, and even more particularly preferably 6 or less. Within this range, good usability without stickiness can be achieved, and stability over time is also improved. In this embodiment, the lower limit of the mass ratio (B) / {(A)+(C)} is not particularly limited because the total amount of components (A) and (C) relative to component (B) becomes excessive, improving stability. However, it is usually preferably 1 or more, more preferably 2 or more, even more preferably 3 or more, even more preferably 3.5 or more, and particularly preferably 3.8 or more.

[0032] In this embodiment, the content of component (B) is preferably 20 to 80% by mass (hereinafter abbreviated as "%"), more preferably 30 to 80%, even more preferably 40 to 80%, and even more preferably 40 to 70%. Within this range, better stability over time and good usability without stickiness can be achieved.

[0033] In this embodiment, the content of component (C) is preferably 1 to 15% by mass (hereinafter abbreviated as "%"), more preferably 2 to 13%, even more preferably 2.5 to 12%, even more preferably 3 to 12%, and particularly preferably 3 to 10%. Within this range, better stability over time and good usability without stickiness can be achieved.

[0034] In the present embodiment, the mass ratio (B) / (C) of the component (B) to the component (C) is preferably 1 to 30, more preferably 2 to 28, even more preferably 4 to 25, still more preferably 6 to 20, particularly preferably 6 to 16, and even more particularly preferably 6 to 15. Within this range, better stability over time and good usability without stickiness can be achieved.

[0035] In the present embodiment, the mass ratio (A) / (C) of the component (A) to the component (C) is preferably 0.1 to 3.0, more preferably 0.2 to 2.8, even more preferably 0.3 to 2.5, still more preferably 0.4 to 2.4, and particularly preferably 0.5 to 2.0. Within this range, better stability over time and good usability without stickiness can be achieved.

[0036] In this embodiment, the content of component (D) is preferably 0.1 to 5 mass% (hereinafter abbreviated as "%"), more preferably 0.3 to 4%, even more preferably 0.5 to 3%, and even more preferably 0.5 to 2%. Within this range, better stability over time and good usability without stickiness can be achieved.

[0037] (3) Method for producing metal oxide dispersion composition

[0038] The method for producing the metal oxide dispersion composition of this embodiment is not particularly limited, but can be obtained, for example, by mixing component (A), component (C), and optional components, adding component (B) to the mixture, and uniformly dispersing the mixture. The optional components include component (D) and oils. Examples of equipment for uniformly dispersing the mixture include a disper mixer, a homomixer, a roll mill, a ball mill, and a bead mill. More preferred are wet-grinding equipment using a medium, such as a roll mill, a ball mill, or a bead mill.

[0039] (4) Purpose

[0040] In addition to cosmetic applications, the metal oxide dispersion composition of this embodiment can also be used in pharmaceuticals such as external skin preparations, paints, inks, optical filters, and inlay paper.

[0041] 2. Second embodiment

[0042] (1) Composition of the Cosmetic The cosmetic of this embodiment contains the metal oxide dispersion composition of the first embodiment. The content of the metal oxide dispersion composition in the cosmetic of this embodiment is preferably 5 to 40%, more preferably 10 to 30%, even more preferably 10 to 25%, and even more preferably 10 to 20%. That is, the cosmetic of this embodiment contains component (A) polyhydroxystearic acid, component (B) a silicone-treated metal oxide, and component (C) glyceryl oleate, and the metal oxide of component (B) is a metal oxide other than titanium oxide. Each component that constitutes the cosmetic will be described below.

[0043] (2) Each component

[0044] The explanation of component (A) polyhydroxystearic acid, component (B) silicone-treated metal oxide, component (C) glyceryl oleate, and component (D) polyhydric alcohol in the first embodiment is also applicable to this embodiment, so further explanation will be omitted.

[0045] To the extent that the effects of this embodiment are not impaired, the cosmetic of this embodiment may, if necessary, be appropriately blended with components typically blended in cosmetics, such as water, oils, powders such as inorganic pigments, organic pigments, and extender pigments, aqueous components such as surfactants, lower alcohols, water-soluble polymers, and moisturizers, sugars, UV absorbers, antioxidants, anti-fading agents, preservatives, medicinal ingredients, stabilizers, pigments, fragrances, etc., in addition to the above-mentioned components, if necessary, to the extent that the effects of this embodiment are not impaired, and each component may be blended separately without preparing the components into a metal oxide dispersion composition.

[0046] In the cosmetic of this embodiment, the content of component (A) is preferably 0.05 to 6% by mass (hereinafter abbreviated as "%"), more preferably 0.1 to 4%, even more preferably 0.2 to 3%, even more preferably 0.4 to 2.5%, and particularly preferably 0.5 to 2%. Within this range, even better stability over time and good usability without stickiness can be achieved.

[0047] In the cosmetic of this embodiment, the mass ratio (B) / {(A)+(C)} of the content of component (B) to the total content of component (A) and component (C) is preferably less than 12, more preferably 10 or less, even more preferably 9 or less, even more preferably 8 or less, particularly preferably 7 or less, and most particularly preferably 6 or less. Within this range, the cosmetic can further impart good usability without stickiness and improve stability over time. In this embodiment, the lower limit of the mass ratio (B) / {(A)+(C)} is not particularly limited because the total amount of component (A) and component (C) becomes excessive relative to component (B), improving stability. However, typically, 1 or more is preferred, 2 or more is more preferred, 3 or more is even more preferred, 3.5 or more is even more preferred, and 3.8 or more is particularly preferred.

[0048] In the cosmetic of this embodiment, the content of component (B) is preferably 1 to 35% by mass (hereinafter abbreviated as "%"), more preferably 1 to 30%, even more preferably 2 to 28%, even more preferably 4 to 20%, and particularly preferably 4 to 15%. Within this range, even better stability over time and good usability without stickiness can be achieved.

[0049] In the cosmetic of this embodiment, the content of component (C) is preferably 0.05 to 6% by mass (hereinafter abbreviated as "%"), more preferably 0.1 to 4%, even more preferably 0.15 to 3%, still more preferably 0.2 to 2%, particularly preferably 0.3 to 2%, and most particularly preferably 0.4 to 2%. Within this range, even better stability over time and good usability without stickiness can be achieved.

[0050] In the cosmetic of this embodiment, the mass ratio (B) / (C) of the component (B) to the component (C) is preferably 1 to 30, more preferably 2 to 28, even more preferably 4 to 25, still more preferably 6 to 20, particularly preferably 6 to 16, and even more particularly preferably 6 to 15. Within this range, even better stability over time and good usability without stickiness can be achieved.

[0051] In the cosmetic of this embodiment, the mass ratio (A) / (C) of the component (A) to the component (C) is preferably 0.1 to 3.0, more preferably 0.2 to 2.8, even more preferably 0.3 to 2.5, still more preferably 0.4 to 2.4, and particularly preferably 0.5 to 2.0. Within this range, better stability over time and good usability without stickiness can be achieved.

[0052] In the cosmetic of this embodiment, the content of component (D) is preferably 0.1 to 10% by mass (hereinafter abbreviated as "%"), more preferably 0.3 to 8%, even more preferably 0.5 to 6%, even more preferably 0.5 to 4%, and particularly preferably 0.5 to 3%. Within this range, even better stability over time and good usability without stickiness can be achieved.

[0053] When the cosmetic preparation of the present embodiment is an oil-in-water emulsion type, it contains water. The water is used as a dispersion medium, and examples thereof include, but are not limited to, purified water, distilled water, ion-exchanged water, tap water, hot spring water, and deep-sea water.

[0054] The content of water is not particularly limited, but it is preferably 40% or more in the cosmetic.

[0055] The oil agent to be blended in the cosmetic of the present embodiment is not particularly limited as long as it is one that is normally used in cosmetics, etc., and oily components such as higher alcohols, fatty acids, hydrocarbon oils, ester oils, and silicones can be used. For example, higher alcohols such as lauryl alcohol, myristyl alcohol, palmityl alcohol, stearyl alcohol, behenyl alcohol, hexadecyl alcohol, oleyl alcohol, isostearyl alcohol, hexyldodecanol, octyldodecanol, cetostearyl alcohol, decyltetradecanol, cholesterol, phytosterol, sitosterol, and lanosterol; fatty acids such as isostearic acid and oleic acid; hydrocarbon oils such as mineral oil, liquid paraffin, light liquid isoparaffin, α-olefin oligomer, vegetable squalane, squalane, polyisobutylene, polybutene, and hydrogenated polyisobutene; diisobutyl adipate, 2-hexyldecyl adipate, di-2-heptylundecyl adipate, N-alkyl glycol monoisostearate, isocetyl isostearate, trimethylolpropane triisostearate, ethylene glycol di-2-ethylhexanoate, and cetyl 2-ethylhexanoate. Ingredients: ethanol, trimethylolpropane tri-2-ethylhexanoate, pentaerythritol tetra-2-ethylhexanoate, cetyl octanoate, oleyl oleate, octyldodecyl oleate, ethyl oleate, decyl oleate, neopentyl glycol dicaprate, triethyl citrate, 2-ethylhexyl succinate, isocetyl stearate, butyl stearate, diisopropyl sebacate, di-2-ethylhexyl sebacate, cetyl lactate, myristyl lactate, palmitate isopropyl phosphate, 2-ethylhexyl palmitate, 2-hexyldecyl palmitate, 2-heptylundecyl palmitate, ethylhexyl salicylate, cholesteryl 12-hydroxystearate, dioctyldodecyl lauroyl glutamate, di(cholesteryl / octyldodecyl) lauroyl glutamate, di(cholesteryl / behenyl / octyldodecyl) lauroyl glutamate, di(octyldodecyl / phytosteryl / behenyl) lauroyl glutamatePhytosteryl / Isostearyl / Cetyl / Stearyl / Behenyl Dimer Dilinoleate, Diisostearyl / Phytosteryl Dimer Dilinoleate, Bisisostearyl Dimer Dilinoleate, Dimer Dilinoleyl Diisostearate, Dipentaerythritol (12-Hydroxystearic Acid / Stearic Acid / Rosin Acid), Dipentaerythritol Hexa(Hydroxystearic Acid / Stearic Acid / Rosin Acid), 12-Hydroxystearic Acid / Isostearic Acid Acid) Dipentaerythritol, Cholesteryl Isostearate, Cholesteryl Hydroxystearate, Cholesteryl Ricinoleate, Macadamia Nut Oil Fatty Acid Phytosteryl, Phytosteryl Oleate, Isopropyl Myristate, Octyldodecyl Myristate, 2-Hexyldecyl Myristate, Myristyl Myristate, Hexyldecyl Dimethyloctanoate, Ethyl Laurate, Hexyl Laurate, Diisostearyl Malate, Ethylhexyl Hydroxystearate, Tri-2-Ethylhexyl Ester oils such as glyceryl xanthate, waxes such as beeswax, carnauba wax, candelilla wax, and spermaceti, vegetable oils and fats typified by palm oil, palm kernel oil, olive oil, safflower oil, soybean oil, and cottonseed oil, animal oils such as beef tallow, beef leg fat, beef bone fat, hardened beef tallow, hardened oil, turtle oil, lard, horse fat, mink oil, liver oil, and egg yolk oil, lanolin, liquid lanolin, reduced lanolin, lanolin alcohol, hard lanolin, lanolin acetate, and lanolin derivatives such as isopropyl lanolin fatty acid, methylpolysiloxane, methylphenyl Examples of the oily component include silicones such as polysiloxane, polyoxyalkylene-alkylmethylpolysiloxane-methylpolysiloxane copolymer, alkoxy-modified polysiloxane, alkyl-modified polysiloxane, crosslinked organopolysiloxane, fluorine-modified polysiloxane, amino-modified polysiloxane, glycerin-modified polysiloxane, higher alkoxy-modified silicone, higher fatty acid-modified silicone, silicone resin, and silicone resin. One or more of these oily components can be used. As the dispersion medium for the dispersion composition of this embodiment 1, it is preferable to use ester oil.

[0056] The cosmetic of the present embodiment can contain powder components other than component (B). The powder contained in the cosmetic is not particularly limited by its shape (e.g., spherical, plate-like, acicular, etc.), particle size (e.g., aerosol, fine particles, pigment-grade, etc.), particle structure (e.g., porous, non-porous, etc.), and examples thereof include inorganic powders, glitter powders, organic powders, pigment powders, metal powders, composite powders, etc.Specific examples include white inorganic pigments such as titanium oxide, zinc oxide, cerium oxide, and barium sulfate; colored inorganic pigments such as iron oxide, carbon black, titanium / titanium oxide sintered product, chromium oxide, chromium hydroxide, iron blue, and ultramarine; talc, muscovite, phlogopite, lepidolite, biotite, synthetic mica, sericite (sericite), synthetic sericite, silicon carbide, silicon dioxide, aluminum oxide, magnesium oxide, zirconium oxide, antimony oxide, diatomaceous earth, aluminum silicate, aluminum magnesium metasilicate, calcium silicate, barium silicate, magnesium silicate, and magnesium silicate. White body powders such as magnesium, calcium carbonate, magnesium carbonate, hydroxyapatite, boron nitride, etc., clay minerals such as kaolin, bentonite, smectite, hectorite, montmorillonite, etc., and their organically modified products, titanium oxide coated mica, titanium oxide coated bismuth oxychloride, iron oxide titanium mica, Prussian blue treated titanium mica, carmine treated titanium mica, bismuth oxychloride, fish scale foil, polyethylene terephthalate-aluminum-epoxy laminated powder, polyethylene terephthalate-polyolefin laminated film powder, polyethylene terephthalate Powder of polymethylmethacrylate laminated film, glittering powder such as titanium oxide coated glass flakes, organic polymer resin powder such as polyamide resin, polyethylene resin, polyacrylic resin, polyester resin, fluorine resin, cellulose resin, polystyrene resin, copolymer resin such as styrene-acrylic copolymer resin, polypropylene resin, silicone resin, urethane resin, organic low molecular weight powder such as zinc stearate and N-acyl lysine, natural organic powder such as silk powder and cellulose powder, Red No. 201, Red No. 202, Red 2 Examples of suitable pigment powders include organic pigment powders such as Red No. 05, Red No. 226, Red No. 228, Orange No. 203, Orange No. 204, Blue No. 404, and Yellow No. 401; organic pigment powders such as zirconium, barium, or aluminum lakes such as Red No. 3, Red No. 104, Red No. 106, Orange No. 205, Yellow No. 4, Yellow No. 5, Green No. 3, and Blue No. 1; and metal powders such as aluminum powder, gold powder, and silver powder; and composite powders such as fine particle titanium oxide-coated mica titanium, fine particle zinc oxide-coated mica titanium, barium sulfate-coated mica titanium, titanium oxide-containing silicon dioxide, and zinc oxide-containing silicon dioxide.These powders may be used singly or in combination of two or more thereof, and may also be used in combination. These powders may be surface-treated with one or more of fluorine-based compounds, silicone-based compounds, metal soaps, lecithin, hydrogenated lecithin, collagen, hydrocarbons, higher fatty acids, higher alcohols, esters, waxes, surfactants, etc.

[0057] The cosmetic of this embodiment can contain a surfactant, and examples of surfactants that can be contained in the cosmetic include nonionic surfactants, anionic surfactants, cationic surfactants, amphoteric surfactants, etc. Examples of nonionic surfactants include polyoxyethylene fatty acid esters, polyoxyethylene sorbitan fatty acid esters, polyoxyethylene hydrogenated castor oil, hydrogenated castor oil, polyoxyethylene sorbitol tetrafatty acid esters, glycerin fatty acid esters, sorbitan fatty acid esters, polyglycerin fatty acid esters, sucrose fatty acid esters, alkyl polyglucosides, N-alkyldimethylamine oxide polyoxyethylene glycerin fatty acid esters, polyoxyethylene cholesteryl ethers, polyoxyethylene phytosteryl ethers, polyoxyethylene alkyl ethers, polyoxyethylene polyoxypropylene alkyl ethers, polyoxyethylene alkylphenyl ethers, polyether-modified silicones, polyether-alkyl-co-modified silicones, polyether-alkyl-siloxyethyl-co-modified silicones, polyglycerin-modified silicones, polyglycerin-alkyl-co-modified silicones, and polyglycerin-alkyl-siloxyethyl-co-modified silicones. Examples of anionic surfactants include sodium salts or triethanolamine salts of fatty acids such as lauric acid, myristic acid, palmitic acid, stearic acid, and isostearic acid; N-acyl methyl taurine salts such as sodium cocoyl methyl taurate, sodium lauroyl methyl taurate, sodium myristoyl methyl taurate, sodium palmitoyl methyl taurate, and sodium stearoyl methyl taurate; and polyoxyethylene alkyl ether phosphates such as polyoxyethylene lauryl ether phosphate, polyoxyethylene cetyl ether phosphate, polyoxyethylene oleyl ether phosphate, and polyoxyethylene nonylphenyl ether phosphate.Examples of cationic surfactants include stearyltrimethylammonium chloride, stearyltrimethylammonium bromide, behenyltrimethylammonium chloride, behenyltrimethylammonium bromide, cetyltrimethylammonium chloride, cetyltrimethylammonium bromide, distearyldimethylammonium chloride, distearyldimethylammonium bromide, dibehenyldimethylammonium chloride, dibehenyldimethylammonium bromide, dicetyldimethylammonium chloride, dicetyldimethylammonium bromide, stearyldimethylbenzylammonium chloride, dilauryldimethylammonium chloride, dipolyoxyethylene (15E.O.) coconut oil alkylmethylammonium chloride, dipolyoxyethylene (4E.O.) lauryl ether dimethylammonium chloride, stearic acid amide propyltrimethylammonium chloride, and dicocoyl ethyl hydroxyethylmethylammonium methyl sulfate. For example, amphoteric surfactants include coconut oil fatty acid amidopropyl betaine, octyl dimethylaminoacetic acid betaine, lauric acid amidopropyl betaine, coconut oil fatty acid alkyl dimethylaminoacetic acid betaine, myristyl dimethylaminoacetic acid betaine, cetyl dimethylaminoacetic acid betaine, coconut oil fatty acid amidopropyl dimethylaminoacetic acid betaine, lauric acid amidopropyl dimethylaminoacetic acid betaine, lauryl dihydroxyethyl aminoacetic acid betaine, cetyl dihydroxyethyl aminoacetic acid betaine, coconut oil alkyl sulfobetaine, lauryl sulfobetaine, N-coconut oil Examples of the lipid activator include betaines such as fatty acid acyl-N-carboxymethyl-N-hydroxyethylethylenediamine sodium and N-coconut oil fatty acid acyl-N-carboxymethoxyethyl-N-carboxymethylethylenediamine disodium, phospholipids such as phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, phosphatidylglycerol, phosphatidylinositol, sphingophospholipid, soybean lecithin, egg yolk lecithin, and hydrogenated products thereof, and phospholipid complexes such as phospholipid-cholesterol complexes and phospholipid-phytosterol complexes.

[0058] The cosmetic of the present embodiment may contain an aqueous component. The aqueous component to be contained in the cosmetic may be any component that is soluble in water, and examples thereof include alcohols such as ethyl alcohol, and plant extracts such as aloe vera, witch hazel, hamamelis, cucumber, lemon, lavender, and rose.

[0059] The cosmetic of the present embodiment may contain a water-soluble polymer. Examples of the water-soluble polymer that may be contained in the cosmetic include natural polymers such as guar gum, sodium chondroitin sulfate, sodium hyaluronate, gum arabic, xanthan gum, sodium alginate, and carrageenan; semi-synthetic polymers such as methyl cellulose, hydroxyethyl cellulose, and carboxymethyl cellulose; carboxyvinyl polymers; alkyl-added carboxyvinyl polymers; polyvinyl alcohol; polyvinylpyrrolidone; sodium polyacrylate; (sodium acrylate / acryloyldimethyltaurine); Examples of the surfactant include synthetic surfactants such as (hydroxyethyl acrylate / sodium acryloyldimethyltaurate) copolymer, (hydroxyethyl acrylate / sodium acryloyldimethyltaurate) copolymer, (acrylates / stearyl methacrylate) copolymer, (acrylates / beheneth-25 methacrylate) copolymer, (PEG-240 / decyltetradeceth-20 / HDI) copolymer, (ammonium acryloyldimethyltaurate / beheneth-25 methacrylate) crosspolymer, and (ammonium acryloyldimethyltaurate / VP) copolymer, as well as proteins, mucopolysaccharides, collagen, elastin, and keratin.

[0060] The cosmetic of the present embodiment may contain additives, and examples of additives that may be contained in the cosmetic include antioxidants such as α-tocopherol and ascorbic acid, vitamins, anti-inflammatory agents, cosmetic ingredients such as herbal medicines, and preservatives such as parahydroxybenzoates and phenoxyethanol.

[0061] (3) Manufacturing method of cosmetics

[0062] The method for producing the cosmetic of the present embodiment is not particularly limited, but for example, the cosmetic can be obtained by adding a mixture of a metal oxide dispersion composition containing components (A), (B), and (C) and an optional oil agent to a uniformly mixed surfactant and aqueous component to emulsify the mixture, and then filling the resulting mixture into a container or mold.

[0063] (4) Purpose

[0064] The cosmetic of this embodiment is not particularly limited, and examples of its form include liquid, semi-solid, and solid. Furthermore, its formulation and product form are not particularly limited, and it can be in the form of a water-in-oil emulsion, an oil-in-water emulsion, a water dispersion, a powder, or the like, with an oil-in-water emulsion being particularly preferred. Examples of product forms include skin cosmetics such as facial cleanser / cream, cleanser, massage cream, pack, lotion, emulsion, cream, serum, makeup base, and sunscreen; finishing cosmetics such as foundation, face powder, eyeshadow, eyeliner, mascara, eyebrow makeup, concealer, lipstick, and lip balm; and hair cosmetics such as hair mists, shampoos, rinses, treatments, hair tonics, hair creams, pomades, makeup sticks, liquid hair styling products, setting lotions, hair sprays, and hair dyes. Among these, cosmetics for sunscreen applications such as sunscreens, daytime serums, foundations, and makeup bases are cosmetics that are likely to exhibit the effects of this embodiment.

[0065] 3. Third embodiment

[0066] (1) Composition of topical skin preparations

[0067] The topical skin preparation of this embodiment contains the metal oxide dispersion composition of the first embodiment. The content of the metal oxide dispersion composition in the topical skin preparation of this embodiment is preferably 5 to 40%, more preferably 10 to 30%, and even more preferably 10 to 20%. That is, the topical skin preparation of this embodiment contains component (A) polyhydroxystearic acid, component (B) a silicone-treated metal oxide, and component (C) glyceryl oleate, and the metal oxide of component (B) is a metal oxide other than titanium oxide. Each component constituting the topical skin preparation will be described below.

[0068] (2) Each component

[0069] The explanation of component (A) polyhydroxystearic acid, component (B) silicone-treated metal oxide, component (C) glyceryl oleate, and component (D) polyhydric alcohol in the first embodiment is also applicable to this embodiment, so further explanation will be omitted.

[0070] The topical skin preparation of this embodiment may contain ingredients used in topical skin preparations, namely, water (purified water, hot spring water, deep sea water, etc.), oils, surfactants, metal soaps, gelling agents, powders, water-soluble polymers, film-forming agents, resins, UV protection agents, inclusion compounds, antibacterial agents, fragrances, deodorants, salts, pH adjusters, cooling agents, animal- or microorganism-derived extracts, plant extracts, blood circulation promoters, astringents, antiseborrheic agents, whitening agents, anti-inflammatory agents, active oxygen scavengers, cell activators, moisturizers, chelating agents, keratolytic agents, enzymes, hormones, vitamins, etc.

[0071] In the topical skin preparation of this embodiment, the content of component (A) is preferably 0.05 to 6% by mass (hereinafter abbreviated as "%"), more preferably 0.1 to 4%, even more preferably 0.2 to 3%, even more preferably 0.4 to 2.5%, and particularly preferably 0.5 to 2%. This range can provide even better stability over time and good usability without stickiness.

[0072] In the external skin preparation of this embodiment, the content mass ratio (B) / {(A)+(C)} of the component (B) to the total content of the component (A) and the component (C) is preferably less than 12, more preferably 10 or less, even more preferably 9 or less, even more preferably 8 or less, particularly preferably 7 or less, and even more particularly preferably 6 or less.Within this range, it is possible to provide a good usability without stickiness and improve stability over time.In this embodiment, the lower limit of the content mass ratio (B) / {(A)+(C)} is not particularly limited, because the total amount of the component (A) and the component (C) becomes excessive relative to the component (B), improving stability, but is usually preferably 1 or more, more preferably 2 or more, even more preferably 3 or more, even more preferably 3.5 or more, and particularly preferably 3.8 or more.

[0073] In the topical skin preparation of this embodiment, the content of component (B) is preferably 1 to 35% by mass (hereinafter abbreviated as "%"), more preferably 1 to 30%, even more preferably 2 to 28%, even more preferably 4 to 20%, and particularly preferably 4 to 15%. Within this range, better stability over time and good usability without stickiness can be achieved.

[0074] In the topical skin preparation of this embodiment, the content of component (C) is preferably 0.05 to 6% by mass (hereinafter abbreviated as "%"), more preferably 0.1 to 4%, even more preferably 0.15 to 3%, still more preferably 0.2 to 2%, particularly preferably 0.3 to 2%, and even more particularly preferably 0.4 to 2%. Within this range, even better stability over time and good usability without stickiness can be achieved.

[0075] In the topical skin preparation of this embodiment, the mass ratio (B) / (C) of the component (B) to the component (C) is preferably 1 to 30, more preferably 2 to 28, even more preferably 4 to 25, still more preferably 6 to 20, particularly preferably 6 to 16, and even more particularly preferably 6 to 15. Within this range, better stability over time and good usability without stickiness can be achieved.

[0076] In the topical skin preparation of this embodiment, the mass ratio (A) / (C) of the component (A) to the component (C) is preferably 0.1 to 3.0, more preferably 0.2 to 2.8, even more preferably 0.3 to 2.5, still more preferably 0.4 to 2.4, and particularly preferably 0.5 to 2.0. Within this range, better stability over time and good usability without stickiness can be achieved.

[0077] In the topical skin preparation of this embodiment, the content of component (D) is preferably 0.1 to 10% by mass (hereinafter abbreviated as "%"), more preferably 0.3 to 8%, even more preferably 0.5 to 6%, even more preferably 0.5 to 4%, and particularly preferably 0.5 to 3%. This range can provide even better stability over time and good usability without stickiness.

[0078] (3) Manufacturing method of topical skin preparation

[0079] The method for producing the topical skin preparation of this embodiment is not particularly limited, and the preparation can be prepared by a conventional method, for example, by adding the above-mentioned components (A) to (C) and, if necessary, the above-mentioned optional components, and mixing them.

[0080] (4) Purpose

[0081] The topical skin preparation of this embodiment can be implemented in various forms such as liquid, gel, cream, solid, mousse, etc., and may be placed in a container capable of spraying mist and sprayed as a mist. The dosage form of this embodiment is not particularly limited, and may include solubilized, oil-in-water emulsion, water-in-oil emulsion, oil-based, water-in-oil-in-water, oil-in-water-in-oil, and multi-layered types, but is particularly preferably an oil-in-water emulsion.

[0082] There are no particular limitations on the use of the topical skin preparation of this embodiment, and it can be used as a topical skin preparation that has excellent anti-aging effects, etc.

[0083] Examples of topical skin preparations of this embodiment are not particularly limited and may be in any form, such as skin care cosmetics such as emulsions, creams, lotions, serums, sunscreens, and packs, makeup cosmetics such as foundations, blushers, lipsticks, eye color, mascara, eyeliner, and nail polish, hair cosmetics such as hair care products, hair tonics, shampoos, rinses, and hair wax, cleansers such as facial cleansers, topical gels, creams, ointments, liquids, liniments, poultices, and aerosols. Among these, topical skin preparations that have sunscreen applications, such as sunscreens, foundations, and daytime serums, are topical skin preparations that are likely to exhibit the effects of this embodiment.

[0084] 4. Fourth embodiment

[0085] (1) Composition of cosmetics

[0086] The cosmetic of the present embodiment contains component (A) polyhydroxystearic acid, component (B) silicone-treated metal oxide, and component (C) glyceryl oleate, and the metal oxide of component (B) is a metal oxide other than titanium oxide.

[0087] (2) Each component

[0088] The explanation of component (A) polyhydroxystearic acid, component (B) silicone-treated metal oxide, component (C) glyceryl oleate, and component (D) polyhydric alcohol in the second embodiment also applies to this embodiment, so further explanation will be omitted.

[0089] The cosmetic of this embodiment may contain, as necessary, components typically contained in cosmetics to impart various effects, other than the above-mentioned components, such as water, oils, powders of inorganic pigments, organic pigments, and extender pigments, aqueous components such as surfactants, lower alcohols, water-soluble polymers, and moisturizers, sugars, UV absorbers, antioxidants, discoloration inhibitors, preservatives, medicinal ingredients, stabilizers, colorants, fragrances, etc. The explanation for the second embodiment above also applies to this embodiment, and therefore a detailed explanation will be omitted.

[0090] The contents of the respective components and the mass ratios of the respective components are the same as those described in the second embodiment, and therefore will not be described here.

[0091] (3) Manufacturing method of cosmetics

[0092] The method for producing the cosmetic of the present embodiment is not particularly limited, but for example, a mixture of component (A), component (B), component (C), and an optional oil agent is added to a uniformly mixed surfactant and aqueous component, emulsified, and then the resulting mixture is filled into a container or mold to obtain the cosmetic.

[0093] (4) Purpose

[0094] The use of the cosmetic material of this embodiment will not be described here because the description of the second embodiment above also applies to this embodiment.

[0095] 5. Fifth embodiment

[0096] (1) Composition of topical skin preparations

[0097] The topical skin preparation of this embodiment contains component (A) polyhydroxystearic acid, component (B) a silicone-treated metal oxide, and component (C) glyceryl oleate, and the metal oxide of component (B) is a metal oxide other than titanium oxide.

[0098] (2) Each component

[0099] The explanation of component (A) polyhydroxystearic acid, component (B) silicone-treated metal oxide, component (C) glyceryl oleate, and component (D) polyhydric alcohol in the third embodiment also applies to this embodiment, so further explanation will be omitted.

[0100] The topical skin preparation of this embodiment may contain ingredients used in topical skin preparations, namely, water (purified water, hot spring water, deep sea water, etc.), oils, surfactants, metal soaps, gelling agents, powders, water-soluble polymers, film-forming agents, resins, UV protection agents, inclusion compounds, antibacterial agents, fragrances, deodorants, salts, pH adjusters, cooling agents, animal- or microorganism-derived extracts, plant extracts, blood circulation promoters, astringents, antiseborrheic agents, whitening agents, anti-inflammatory agents, active oxygen scavengers, cell activators, moisturizers, chelating agents, keratolytic agents, enzymes, hormones, vitamins, etc. The explanation of water (purified water, hot spring water, deep sea water, etc.), oils, surfactants, metal soaps, gelling agents, powders, water-soluble polymers, film-forming agents, resins, UV protection agents, inclusion compounds, antibacterial agents, fragrances, deodorants, salts, pH adjusters, fresheners, animal- and microorganism-derived extracts, plant extracts, blood circulation promoters, astringents, antiseborrheic agents, whitening agents, anti-inflammatory agents, active oxygen scavengers, cell activators, moisturizers, chelating agents, keratolytic agents, enzymes, hormones, vitamins, etc., as described in the third embodiment above, also applies to this embodiment, and therefore will not be repeated here.

[0101] The contents of the respective components and the mass ratios between the respective components are the same as those described in the third embodiment, and therefore will not be described here.

[0102] (3) Manufacturing method of topical skin preparation

[0103] The method for producing the topical skin preparation of this embodiment is not particularly limited, and the preparation can be prepared by a conventional method, for example, by adding the above-mentioned components (A) to (C) and, if necessary, the above-mentioned optional components, and mixing them.

[0104] (4) Purpose

[0105] The use of the external skin preparation of this embodiment is the same as that of the third embodiment, and therefore will not be described here.

[0106] In addition to the above-described embodiments, the present invention can also employ the following configurations. [1] A metal oxide dispersion composition containing the following components (A) to (C): (A) polyhydroxystearic acid, (B) a silicone-treated metal oxide, and (C) glyceryl oleate, wherein the metal oxide of component (B) is a metal oxide other than titanium oxide. [2] The metal oxide dispersion composition according to [1], wherein the mass ratio of component (B) to the total content of components (A) and (C), (B) / {(A) + (C)}, is less than 12. [3] The metal oxide dispersion composition according to [1] or [2], wherein component (B) is a dimethylpolysiloxane-treated metal oxide. [4] The metal oxide dispersion composition according to any one of [1] to [3], wherein the content of component (B) is 20 to 80 mass%. [5] The metal oxide dispersion composition according to any one of [1] to [4], wherein the mass ratio (B) / (C) of the content of the component (B) to the content of the component (C) is 1 to 30. [6] The metal oxide dispersion composition according to any one of [1] to [5], wherein the mass ratio (A) / (C) of the content of the component (A) to the content of the component (C) is 0.1 to 3.0. [7] The metal oxide dispersion composition according to any one of [1] to [6], wherein the metal oxide of the component (B) is zinc oxide. [8] The metal oxide dispersion composition according to any one of [1] to [7], further comprising a polyhydric alcohol as component (D). [9] A cosmetic or topical skin preparation comprising the metal oxide dispersion composition according to any one of [1] to [8].

[10] The cosmetic or topical skin preparation according to [9], wherein the cosmetic or topical skin preparation is an oil-in-water emulsion type.

[11] The cosmetic or topical skin preparation according to [9] or

[10] , wherein the cosmetic or topical skin preparation is used for sunscreen purposes.

[12] A cosmetic or topical skin preparation containing the following components (A) to (C): (A) polyhydroxystearic acid, (B) a silicone-treated metal oxide, and (C) glyceryl oleate, wherein the metal oxide of component (B) is a metal oxide other than titanium oxide.

[13] The cosmetic or topical skin preparation according to

[12] , wherein the mass ratio (B) / {(A) + (C)} of the content of component (B) to the total content of components (A) and (C) is less than 12.

[14] The cosmetic or topical skin preparation according to

[12] or

[13] , wherein the component (B) is a dimethylpolysiloxane-treated metal oxide.

[15] The cosmetic or topical skin preparation according to any one of

[12] to

[14] , wherein the content of the component (B) is 1 to 35% by mass.

[16] The cosmetic or topical skin preparation according to any one of

[12] to

[15] , wherein the mass ratio (B) / (C) of the component (B) to the component (C) is 1 to 30.

[17] The cosmetic or topical skin preparation according to any one of

[12] to

[16] , wherein the mass ratio (A) / (C) of the component (A) to the component (C) is 0.1 to 3.0.

[18] The cosmetic or topical skin preparation according to any one of

[12] to

[17] , wherein the metal oxide of the component (B) is zinc oxide.

[19] The cosmetic or topical skin preparation according to any one of

[12] to

[18] , further comprising a component (D) polyhydric alcohol.

[20] The cosmetic or topical skin preparation according to

[19] , wherein the component (D) is glycerin.

[21] The cosmetic or topical skin preparation according to any one of

[12] to

[20] , which is an oil-in-water emulsion.

[22] The cosmetic or topical skin preparation according to any one of

[12] to

[21] , which is used for sunscreen purposes.

[0107] 6. Working Example

[0108] The present invention will be described in more detail below with reference to examples, but the present invention is not limited to these examples. Unless otherwise specified, the content is expressed in mass % relative to the system in which the component is contained.

[0109] 6-1. Production of metal oxide dispersion composition

[0110] [Examples 1 to 7, Comparative Examples 1 to 5]

[0111] Metal oxide dispersion compositions having the compositions shown in Table 1 below were prepared by the manufacturing method described below, and the "dispersibility" of each sample was evaluated and judged using the evaluation method and criteria described below. The results are also shown in Table 1.

[0112]

[0113] (Note 1) Salacos HS-6C (manufactured by Nisshin Oillio Group) (Note 2) CITHROL DPHS (manufactured by Croda Japan) (Note 3) Sunsoft No. 818R-C (manufactured by Taiyo Kagaku Co., Ltd.) (Note 4) Zinc oxide used was MZ-500 (manufactured by Teika Co., Ltd., average particle size: 25 nm), and the amount of dimethylpolysiloxane treatment was 5% of the mass of zinc oxide. (Note 10) MTY-110M3S (manufactured by Teika Co., Ltd.)

[0114] (Production Method) All of the components (1) to (7) were mixed uniformly and dispersed in a roll mill to obtain a metal oxide dispersion composition.

[0115] <Evaluation Method 1: Dispersibility> When the metal oxide is well dispersed, the viscosity of the metal oxide dispersion composition is low. Here, regarding the dispersibility of the present invention, after production, the metal oxide dispersion composition was stored in a thermostatic chamber at 30°C for one day, and then the viscosity of the metal oxide dispersion composition was measured using a B-type viscometer, and the dispersibility was evaluated according to the following three-level evaluation criteria.

[0116] <Three-level evaluation criteria for dispersibility of metal oxide dispersion composition> [Evaluation]: [Evaluation] A (Excellent): Viscosity value is less than 10,000 mPa·s B (Good): Viscosity value is 10,000 mPa·s or more but less than 20,000 mPa·s C (Poor): Viscosity value is 20,000 mPa·s or more

[0117] As shown in Table 1, the metal oxide dispersion compositions of Examples 1 to 7, which contained dimethylpolysiloxane-treated zinc oxide (a silicone-treated metal oxide), polyhydroxystearic acid, and glyceryl oleate, were excellent in "dispersibility." On the other hand, the metal oxide dispersion compositions of Comparative Example 1, in which PEG-30 dipolyhydroxystearate was used instead of polyhydroxystearic acid, Comparative Example 2, in which polyglyceryl-5 polyricinoleate was used, Comparative Example 3, which was prepared in the same manner as Example 1 except that glyceryl oleate was not contained, Comparative Example 4, which was prepared in the same manner as Example 1 except that polyhydroxystearic acid was not contained, and Comparative Example 5, in which silicone-treated titanium oxide (MTY-110M3S, manufactured by Teika Corporation) was used instead of dimethylpolysiloxane-treated zinc oxide, were inferior in "dispersibility" to Example 1.

[0118] 4-2. Cosmetic manufacturing

[0119] [Examples 8 to 14, Comparative Examples 6 to 11]

[0120] Oil-in-water emulsion cosmetics (sunscreens) having the compositions shown in Table 2 below were prepared by the manufacturing method described below, and evaluated for "stability over time (40°C / 1 month)" and "non-stickiness" using the evaluation methods and criteria described below, with the results also shown in Table 2. Photographs of the appearance of the oil-in-water emulsion cosmetics of Example 8 and Comparative Example 6 for stability over time (40°C / 1 month) are shown in Figure 1. In Comparative Example 6, the metal oxide dispersion composition of Comparative Example 1 was used instead of the metal oxide dispersion composition of Example 1; in Comparative Example 7, the metal oxide dispersion composition of Comparative Example 2 was used instead of the metal oxide dispersion composition of Example 1; in Comparative Example 8, the metal oxide dispersion composition of Comparative Example 3 was used instead of the metal oxide dispersion composition of Example 1; in Comparative Example 9, the metal oxide dispersion composition of Comparative Example 4 was used instead of the metal oxide dispersion composition of Example 1; in Comparative Example 10, the metal oxide dispersion composition of Comparative Example 5 was used instead of the metal oxide dispersion composition of Example 1; and in Comparative Example 11, a metal oxide dispersion composition (Reference Example 1) prepared in the same manner as Example 1 except that glyceryl stearate was used instead of glyceryl oleate was used, and the oil-in-water emulsion cosmetic was prepared by the production method described below.

[0121]

[0122] (Note 5) TINOSORB S (manufactured by BASF) (Note 6) Ubinal A PLUS GRANULAR (manufactured by BASF) (Note 7) SIMULGEL EG QD (manufactured by SEPPIC) (purity: 37.5%) (Note 8) Godball D11-796C (manufactured by Suzuki Oil Industries Co., Ltd.)

[0123] (Manufacturing method)

[0124] A: Components (14) to (16) were mixed, and then (1) to (13) were added and mixed to disperse. B: Components (17) to (22) were mixed uniformly, and then A was added thereto and emulsified, followed by degassing to obtain an oil-in-water emulsion cosmetic.

[0125] <Evaluation method 2: Stability over time (40°C / 1 month)> If the stability of the metal oxide dispersion composition and the oil-in-water emulsion cosmetic is good, the viscosity change over time shown below will be small, but if the stability is poor, the viscosity change over time will be large (gelation will occur). For the stability over time (40°C / 1 month) of the present invention, the viscosity value measured with a B-type viscometer after storing each cosmetic for one day in a 30°C thermostatic bath after production was compared with the viscosity value measured with a B-type viscometer after storing in a 40°C thermostatic bath for one month and then storing in a 30°C thermostatic bath for one day, and the stability was judged according to the following three-level judgment criteria.

[0126] <Three-level evaluation criteria for stability over time> [Evaluation]: [Evaluation] A (Excellent): Viscosity change is 0 mPa·s or more and less than ±5,000 mPa·s B (Good): Viscosity change is ±5,000 mPa·s or more and less than ±15,000 mPa·s C (Poor): Viscosity change is ±15,000 mPa·s or more

[0127] <Evaluation Method 3: Non-stickiness> The following sensory evaluation test was conducted for non-stickiness. Ten expert panelists in their 20s to 40s who had received sensory evaluation training and were capable of evaluation according to certain standards were selected. The expert panelists applied 2 g of each sample to their forearms, and for each sample, the non-stickiness upon application was evaluated and scored on a 5-point absolute scale as shown below. For each sample, the average score was calculated from the total scores of all panelists, and the results were judged according to the 4-point rating scale shown below.

[0128] <Absolute evaluation criteria> [Score]: [Evaluation] 5 points: Not sticky 4 points: Almost not sticky 3 points: Slightly sticky 2 points: Sticky 1 point: Very sticky

[0129] <4-level evaluation criteria> [Evaluation]: [Average score] A (Excellent): Over 4.5 points B (Good): Over 3.5 points and 4.5 points or less C (Slightly poor): Over 1.5 points and 3.5 points or less D (Poor): 1.5 points or less

[0130] As shown in Table 2, the oil-in-water emulsion cosmetics of Examples 8 to 14, which used the metal oxide dispersion compositions of Examples 1 to 7 containing dimethylpolysiloxane-treated zinc oxide (a silicone-treated metal oxide), polyhydroxystearic acid, and glyceryl oleate, were excellent in both "stability over time" and "non-stickiness." On the other hand, the oil-in-water emulsion cosmetics of Comparative Example 6, which used the metal oxide dispersion composition of Comparative Example 1 instead of the metal oxide dispersion compositions of Examples 1 to 7, Comparative Example 7, which used the metal oxide dispersion composition of Comparative Example 2, Comparative Example 8, which used the metal oxide dispersion composition of Comparative Example 3, Comparative Example 9, which used the metal oxide dispersion composition of Comparative Example 4, and Comparative Example 10, which used the metal oxide dispersion composition of Comparative Example 5, were inferior in both "stability over time" and "non-stickiness" to the oil-in-water emulsion cosmetics of Examples 8 to 14. Furthermore, as shown in Figure 1 (left), the oil-in-water emulsion cosmetic of Example 8 showed no gelation even after being stored in a 40°C thermostatic chamber for one month, demonstrating excellent stability over time.

[0131] 1 (right), gelation was observed over time and stability over time was insufficient in Comparative Example 6, which used the metal oxide dispersion composition of Comparative Example 1 instead of the metal oxide dispersion composition of Example 1. Furthermore, the oil-in-water emulsion cosmetic of Comparative Example 11, which used a metal oxide dispersion composition (Reference Example 1) prepared by replacing the glyceryl oleate of Example 1 with glyceryl stearate, felt very sticky upon application and was unsatisfactory in terms of usability.

[0132] Example 15: Daytime serum (oil-in-water emulsion)

[0133] An oil-in-water emulsion cosmetic (daytime serum) having the following composition was prepared by the following production method.(Ingredients) (% by mass) 1. Dimethylpolysiloxane (10% treated) fine particle zinc oxide (10 nm) (ingredient (B)) 5 2. Polyhydroxystearic acid (Note 1) (ingredient (A)) 1 3. Glyceryl oleate (ingredient (C)) 1 4. Cetyl 2-ethylhexanoate 3 5. Ethylhexyl methoxycinnamate 7 6. Diethylamino hydroxybenzoyl benzoic acid hexyl ester (Note 6) 2 7. 2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (Note 5) 1 8. Di(caprylic / capric acid) propylene glycol 5 9. Niacinamide 5 10. Tranexamic acid 2 11. 10. Sodium Acrylate / Sodium Acryloyldimethyltaurate Copolymer (Note 7) 0.5 11. Xanthan Gum 0.1 12. Sodium Hyaluronate (Note 9) 0.05 13. Glycerin (Component (D)) 2 14. Dipropylene Glycol (Component (D)) 2 15. 1,3-Butylene Glycol (Component (D)) 2 16. Vegetable Squalane 0.5 17. PEG-10 Hydrogenated Castor Oil 0.1 18. PEG-80 Hydrogenated Castor Oil 1.5 20. PEG-40 Hydrogenated Castor Oil 0.3 21. Ethanol 5 22. Purified Water Remaining amount.

[0134] (Note 9) Hyaluronic acid FCH-SU (Kikkoman Biochemifa Corporation)

[0135] (Production Method) A: Components (1) to (4) were mixed and dispersed using a roll mill to prepare a metal oxide dispersion composition. B: Components (5) to (8) were heated and mixed at 75°C, and A was then added and mixed. C: Components (9) to (22) were mixed uniformly, and the mixture was added to B and emulsified to obtain a daytime beauty serum (oil-in-water emulsion).

[0136] The daytime beauty serum of Example 15 (oil-in-water emulsion) was excellent in stability over time and had a non-sticky feel when used.

[0137] Example 16: Daytime serum (oil-in-water emulsion)

[0138] An oil-in-water emulsion cosmetic (daytime serum) having the following composition was prepared by the following manufacturing method. (Components) (% by mass) 1. Stearic acid / AL hydroxide treated fine particle titanium dioxide (10 nm) 10 2. Dimethylpolysiloxane (10% treated) zinc oxide fine particle (25 nm) (Component (B)) 10 3. Polyhydroxystearic acid (Note 1) (Component (A)) 1 4. Glyceryl oleate (Component (C)) 1 5. Glycerin (Component (D)) 0.2 6. 2-ethylhexanoate 5 7. Propylene glycol dicaprate 3 8. Stearyl glycyrrhetinate 0.1 9. (Sodium acrylate / sodium acryloyldimethyltaurate) copolymer (Note 7) 0.5 10. Xanthan gum 0.1 11. Sodium hyaluronate (Note 9) 0.05 12. Glycerin (ingredient (D)) 2 13. Dipropylene glycol (ingredient (D)) 2 14. 1,3-butylene glycol (ingredient (D)) 2 15. PEG-80 hydrogenated castor oil 2 16. Ethanol 5 17. Purified water Remaining amount

[0139] (Production Method) A: Components (1) to (6) were mixed and dispersed using a roll mill to prepare a metal oxide dispersion composition. B: Components (7) to (8) were mixed, and then A was added and mixed. C: Components (9) to (17) were mixed uniformly, and the mixture was added to B and emulsified to obtain a daytime beauty serum (oil-in-water emulsion).

[0140] The daytime beauty serum (oil-in-water emulsion) of Example 16 was excellent in stability over time and had a non-sticky feel when used.

[0141] Example 17: Daytime serum (oil-in-water emulsion)

[0142] An oil-in-water emulsion cosmetic (daytime serum) having the following composition was prepared by the following production method.(Ingredients) (% by mass) 1. Dimethylpolysiloxane (10% treated) fine particle zinc oxide (10 nm) (ingredient (B)) 5 2. Polyhydroxystearic acid (Note 1) (ingredient (A)) 1 3. Glyceryl oleate (ingredient (C)) 1 4. Cetyl 2-ethylhexanoate 3 5. Ethylhexyl methoxycinnamate 7 6. Diethylamino hydroxybenzoyl benzoic acid hexyl ester (Note 6) 2 7. 2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (Note 5) 1 8. Di(caprylic / capric acid) propylene glycol 5 9. Niacinamide 5 10. Tranexamic acid 2 11. 10. Sodium Acrylate / Sodium Acryloyldimethyltaurate Copolymer (Note 7) 0.5 11. Xanthan Gum 0.1 12. Sodium Hyaluronate (Note 9) 0.05 13. Glycerin (Component (D)) 0.5 14. Dipropylene Glycol (Component (D)) 1 15. 16. 1,3-Butylene Glycol (Component (D)) 1.5 17. Vegetable Squalane 0.5 18. Sodium Stearate 1.5 19. Polyglyceryl-10 Stearate 0.5 20. Sodium Stearoyl Methyl Taurate 0.3 21. Ethanol 5 22. Purified Water Remaining amount.

[0143] (Production Method) A: Components (1) to (4) were mixed and dispersed using a roll mill to prepare a metal oxide dispersion composition. B: Components (5) to (8) were mixed, and then A was added and mixed. C: Components (9) to (22) were mixed uniformly, and the mixture was added to B and emulsified to obtain a daytime beauty serum (oil-in-water emulsion).

[0144] The daytime beauty serum (oil-in-water emulsion) of Example 17 was excellent in stability over time and had a non-sticky feel when used.

[0145] Example 18: Daytime serum (oil-in-water emulsion)

[0146] An oil-in-water emulsion cosmetic (daytime serum) having the following composition was prepared by the following manufacturing method. (Components) (% by mass) 1. Stearic acid / AL hydroxide treated fine particle titanium dioxide (10 nm) 10 2. Dimethylpolysiloxane (10% treated) fine particle zinc oxide (25 nm) (Component (B)) 10 3. Polyhydroxystearic acid (Note 1) (Component (A)) 1 4. Glyceryl oleate (Component (C)) 1 5. Glycerin (Component (D)) 0.4 6. 2-ethylhexanoate 5 7. Propylene glycol dicaprate 3 8. Stearyl glycyrrhetinate 0.1 9. (Sodium acrylate / sodium acryloyldimethyltaurate) copolymer (Note 7) 0.5 10. Xanthan gum 0.1 11. Sodium hyaluronate (Note 9) 0.05 12. Glycerin (ingredient (D)) 1 13. Dipropylene glycol (ingredient (D)) 1 14. 1,3-butylene glycol (ingredient (D)) 1 15. PEG-80 hydrogenated castor oil 2 16. Ethanol 5 17. Purified water Remaining amount

[0147] (Production Method) A: Components (1) to (6) were mixed and dispersed using a roll mill to prepare a metal oxide dispersion composition. B: Components (7) to (8) were mixed, and then A was added and mixed. C: Components (9) to (17) were mixed uniformly, and the mixture was added to B and emulsified to obtain a daytime beauty serum (oil-in-water emulsion).

[0148] The daytime beauty serum (oil-in-water emulsion) of Example 18 was excellent in stability over time and had a non-sticky feel when used.

[0149] Example 19: Daytime serum (oil-in-water emulsion)

[0150] An oil-in-water emulsion cosmetic (daytime serum) having the following composition was prepared by the following manufacturing method. (Components) (% by mass) 1. Dimethylpolysiloxane (10% treated) zinc oxide fine particle (10 nm) (Component (B)) 5 2. Polyhydroxystearic acid (Note 1) (Component (A)) 1 3. Glyceryl oleate (Component (C)) 1 4. Sorbitan sesquioleate 0.2 5. Cetyl 2-ethylhexanoate 4 6. Ethylhexyl methoxycinnamate 7 7. Diethylaminohydroxybenzoylbenzoic acid hexyl ester (Note 6) 2 8. 2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (Note 5) 1 9. 10. Propylene Glycol Dicaprylate / Dicaprate 5 10. Niacinamide 5 11. Tranexamic Acid 2 12. (Sodium Acrylate / Sodium Acryloyldimethyltaurate) Copolymer (Note 7) 0.5 13. Xanthan Gum 0.1 14. Sodium Hyaluronate (Note 9) 0.05 15. Glycerin (Component (D)) 2 16. Dipropylene Glycol (Component (D)) 2 17.13-Butylene glycol (ingredient (D)) 2 18. Vegetable squalane 0.5 19. PEG-10 hydrogenated castor oil 0.1 20. PEG-80 hydrogenated castor oil 1.5 21. PEG-40 hydrogenated castor oil 0.3 22. Ethanol 5 23. Purified water Remaining amount,

[0151] (Note 9) Hyaluronic acid FCH-SU (Kikkoman Biochemifa Corporation)

[0152] (Production Method) A: Components (1) to (5) were mixed and dispersed using a roll mill to prepare a metal oxide dispersion composition. B: Components (6) to (9) were heated and mixed at 75°C, and A was then added and mixed. C: Components (10) to (23) were mixed uniformly, and the mixture was added to B and emulsified to obtain a daytime beauty serum (oil-in-water emulsion).

[0153] The daytime beauty serum of Example 19 (oil-in-water emulsion) was excellent in stability over time and had a non-sticky feel when used.

[0154] Example 20: Daytime serum (oil-in-water emulsion)

[0155] An oil-in-water emulsion cosmetic (daytime serum) having the following composition was prepared by the following manufacturing method. (Components) (% by mass) 1. Dimethylpolysiloxane (10% treated) zinc oxide fine particle (10 nm) (Component (B)) 5 2. Polyhydroxystearic acid (Note 1) (Component (A)) 1 3. Glyceryl oleate (Component (C)) 1 4. Sorbitan oleate 0.2 5. Glycerin (Component (D)) 0.1 6. Cetyl 2-ethylhexanoate 3 7. Ethylhexyl methoxycinnamate 7 8. Diethylaminohydroxybenzoylbenzoic acid hexyl ester (Note 6) 2 9. 2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (Note 5) 1 10. 11. Propylene Glycol Dicaprylate / Dicaprate 5 12. Niacinamide 5 13. Tranexamic Acid 2 14. Sodium Acrylate / Sodium Acryloyldimethyltaurate Copolymer (Note 7) 0.5 15. Xanthan Gum 0.1 16. Sodium Hyaluronate (Note 9) 0.05 17. Dipropylene Glycol (Component (D)) 1 18.13-Butylene glycol (ingredient (D)) 0.5 19. Vegetable squalane 0.5 20. Sodium stearate 1.5 21. Polyglyceryl-10 stearate 0.5 22. Sodium stearoyl methyl taurate 0.3 23. Ethanol 5 24. Purified water Remaining amount,

[0156] (Production Method) A: Components (1) to (6) were mixed and dispersed using a roll mill to prepare a metal oxide dispersion composition. B: Components (7) to (10) were mixed, and then A was added and mixed. C: Components (11) to (24) were mixed uniformly, and the mixture was added to B and emulsified to obtain a daytime beauty serum (oil-in-water emulsion).

[0157] The daytime beauty serum of Example 20 (oil-in-water emulsion) was excellent in stability over time and had a non-sticky feel when used.

Claims

1. The following components (A) to (C): (A) polyhydroxystearic acid (B) silicone-treated metal oxide (C) glyceryl oleate, and a metal oxide dispersion composition in which the metal oxide of the component (B) is a metal oxide excluding titanium oxide.

2. The metal oxide dispersion composition according to claim 1, wherein the content mass ratio (B) / {(A)+(C)} of the component (B) to the total content of the component (A) and the component (C) is less than 12.

3. The metal oxide dispersion composition according to claim 1 or 2, wherein the component (B) is a dimethylpolysiloxane-treated metal oxide.

4. The metal oxide dispersion composition according to claim 1 or 2, wherein the content of the component (B) is 20 to 80% by mass.

5. The metal oxide dispersion composition according to claim 1 or 2, wherein the content mass ratio (B) / (C) of the component (B) to the component (C) is 1 to 30.

6. The metal oxide dispersion composition according to claim 1 or 2, wherein the content mass ratio (A) / (C) of the component (A) to the component (C) is 0.1 to 3.

0.

7. The metal oxide dispersion composition according to claim 1 or 2, wherein the metal oxide of the component (B) is zinc oxide.

8. The metal oxide dispersion composition according to claim 1 or 2, further containing a component (D) polyhydric alcohol.

9. A cosmetic or an external preparation for skin containing the metal oxide dispersion composition according to claim 1 or 2.

10. The cosmetic or the external preparation for skin according to claim 9, wherein the cosmetic or the external preparation for skin is of the oil-in-water emulsion type.

11. The cosmetic or the external preparation for skin according to claim 9, wherein the cosmetic or the external preparation for skin is for sunscreen use.

12. The following components (A) to (C): (A) polyhydroxystearic acid (B) silicone-treated metal oxide (C) glyceryl oleate, and a cosmetic or an external preparation for skin in which the metal oxide of the component (B) is a metal oxide excluding titanium oxide.

Images