Wound care formulation and wound dressing for patch-based and GEL-based formulation

Abstract

The present invention discloses wound care formulation, wound dressing, and method for wound care. The wound care formulation is configured to form a stable protection and barrier. The wound care formulation comprises a hydrocolloid material having a hydrated form of a modified metal carbonate. The hydrated form of the modified metal carbonate is prepared by processing the modified metal carbonate. The size of the hydrocolloid material and the modified metal carbonate is between 500nm and 1000nm. The method for wound care comprises applying a hydrocolloid material to a wound surface. The hydrocolloid material is utilized as a standalone component or in combination with antibiotics. The method comprises creating an environment conducive for healing in oral and skin conditions based on the specific characteristics of the wound. The method further comprises selecting the absorbability of the hydrocolloid material based on the specific characteristics of the wound.

Description

[0001]WOUND CARE FORMULATION AND WOUND DRESSING FOR PATCH-BASED AND GEL-BASED FORMULATION FIELD OF THE INVENTION The present invention generally relates to the field of a wound care formulation. More particularly, the present invention relates to a wound care formulation to form a stable protection and barrier, a wound dressing for a patch-based wound care formulation and a gel- based wound care formulation, and a method for wound care formulation. BACKGROUND OF THE INVENTION Hydrocolloid-based wound barriers are a type of dressing used in modern wound care. They are particularly known for their unique properties and composition, which make them suitable for a variety of wound types, especially those that are moderately exuding. Hydrophilic Membranes in Wound Care Absorbing Exudate in Diabetic Ulcers: Diabetic ulcers often produce a significant amount of exudate. Hydrophilic membranes can be used in dressings to absorb this fluid, maintaining a moist environment that promotes healing. Facilitating Autolytic Debridement: For wounds requiring debridement (removal of dead tissue), hydrophilic dressings can facilitate autolytic debridement by retaining moisture and enzymes that help break down dead tissue. Managing Infection Risk: Hydrophilic membranes in wound dressings can be impregnated with antimicrobial agents to reduce the risk of infection, which is particularly important in diabetic wounds. Hydrophobic Membranes in Wound Care Protecting Against External Contamination in Pressure Wounds: Hydrophobic membranes can be used as a top layer in dressings for pressure wounds to protect against external contamination and fluid ingress. Preventing Excessive Moisture: In wounds with lower exudate levels or in later stages of healing, a hydrophobic membrane can prevent excessive moisture buildup, reducing the risk of maceration (softening and breaking down of skin due to prolonged exposure to moisture). Use in Composite Dressings: In some advanced wound dressings, a hydrophobic membrane might be used in combination with other materials. For instance, a hydrophilic layer that faces the wound for moisture management, with a hydrophobic outer layer for protection. The current hydrocolloid-based dressings have several drawbacks. One major issue is the potential for gel leakage, which can cause patient discomfort and hinder maintaining wound cleanliness and dryness. This problem arises due to changes in the hydrocolloid material's hydration. To tackle this, modifications have been introduced to the existing hydrocolloid wound barrier formulation. Another significant concern is the susceptibility to infection. Conventional hydrocolloid dressings often face challenges, which can lead to increased bacterial colonization and delayed wound healing. Other products incorporate metals like silver, which substantially increase the cost of the barrier. Current technologies fail to address complex wound conditions, including pressure, diabetic, and oral ulcers, as well as tooth-related issues. In the oral cavity, the material must form a layer capable of withstanding continuous movement from oral tissues, such as the tongue or cheeks. Similarly, for skin pressure ulcers, it is crucial to maintain sufficient skin thickness to prevent rupture, which could lead to a non-healing ulcer. Therefore, there is a clear need for a wound care formulation that effectively manages complex wound conditions, including pressure, diabetic, and oral ulcers, alongside tooth-related issues. SUMMARY OF THE INVENTION In an embodiment, a wound care formulation to form a stable protection and barrier is disclosed. The wound care formulation comprises a hydrocolloid material having a hydrated form of a modified metal carbonate. The hydrated form of a modified metal carbonate is prepared by processing the modified metal carbonate. The size of the modified metal carbonate is between 500nm and 1000nm. The wound care formulation further comprises a hydrocolloid material being adaptable to absorbable and non-absorbable configurations. The hydrocolloid material includes the modified metal carbonate. The modified metal carbonate is selected from at least one of a lanthanum carbonate, a cerium carbonate, a samarium carbonate, and a gadolinium carbonate. The wound care formulation of the present invention incorporates modified metal carbonates that enhances the wound barrier function, reduces bacterial colonization on the barrier, and improves exudate absorption compared to standard hydrocolloid formulations. These advancements address the limitations of existing dressings, promoting a more effective and accelerated healing process. In another embodiment, a wound dressing for a patch-based wound care formulation and a gel-based wound care formulation is disclosed. The wound dressing comprises a hydrocolloid material configured to provide a non-absorbable barrier or an absorbable form as required by wound characteristics. The patch and gel configurations are differentiable into the absorbable form and the non-absorbable form based on wound characteristics. The patch-based wound care formulation comprises a hydrocolloid-based gel having the hydrocolloid material up to 50% and an emollient up to 30% for non-absorption patches. The gel-based wound care formulation comprises the hydrocolloid-based gel having the hydrocolloid material up to 25% and the emollient up to 30% for non-absorption gel. In another embodiment, a method for wound care is disclosed. The method comprises the step of applying a hydrocolloid material to a wound surface. The hydrocolloid material comprises a modified metal carbonate. The hydrocolloid material is utilized as a standalone component or in combination with antibiotics. The method comprises the step of creating an environment conducive for healing in oral and skin conditions based on the specific characteristics of the wound. The method further comprises the step of selecting the absorbability of the hydrocolloid material based on the specific characteristics of the wound. An object of the present invention is to provide a wound care formulation for managing complex wound conditions including, pressure, diabetic and oral ulcers including tooth related issues which contribute in tooth pain. Another object of the present invention is to provide a cost-effective wound care formulation for oral and skin care. Another object of the present invention is to enhance the use of materials that can, to some degree, reduce this risk of infection. It is appreciated that these drawings depict only typical embodiments of the invention and are therefore not to be considered limiting of its scope. The invention will be described and explained with additional specificity and detail with the accompanying drawings. BRIEF DESCRIPTION OF FIGURES These and other features, aspects, and advantages of the present invention will become better understood when the following detailed description is read with reference to the accompanying drawings in which like characters represent like parts throughout the drawings, wherein: Figure 1 illustrates a block diagram of a wound care formulation; and Figure 2 illustrates a flowchart of a method for wound care. Further, skilled artisans will appreciate that elements in the drawings are illustrated for simplicity and may not have been necessarily been drawn to scale. For example, the figures illustrate the result of the composition with fungal growth and no fungal growth. Furthermore, in terms of the formulation of the mouthwash composition, one or more ingredients of the composition may have been represented in the drawings, and the drawings may show only those specific details that are pertinent to understanding the embodiments of the present invention so as not to obscure the drawings with details that will be readily apparent to those of ordinary skill in the art having benefit of the description herein. DETAILED DESCRIPTION: For the purpose of promoting an understanding of the principles of the invention, reference will now be made to the embodiment illustrated in the drawings and specific language will be used to describe the same. It will nevertheless be understood that no limitation of the scope of the invention is thereby intended, such alterations and further modifications in the illustrated system, and such further applications of the principles of the invention as illustrated therein being contemplated as would normally occur to one skilled in the art to which the invention relates. It will be understood by those skilled in the art that the foregoing general description and the following detailed description are exemplary and explanatory of the invention and are not intended to be restrictive thereof. Reference throughout this specification to “an aspect”, “another aspect” or similar language means that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment of the present invention. Thus, appearances of the phrase “in an embodiment”, “in another embodiment” and similar language throughout this specification may, but do not necessarily, all refer to the same embodiment. The terms "comprises", "comprising", or any other variations thereof, are intended to cover a non-exclusive inclusion, such that a process or method that comprises a list of steps does not include only those steps but may include other steps not expressly listed or inherent to such process or method. Similarly, one or more devices or sub-systems or elements or structures or components proceeded by "comprises...a" does not, without more constraints, preclude the existence of other devices or other sub-systems or other elements or other structures or other components or additional devices or additional sub-systems or additional elements or additional structures or additional components. Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The composition and examples provided herein are illustrative only and not intended to be limiting. Embodiments of the present invention will be described below in detail with reference to the accompanying drawings. Figure 1 illustrates a block diagram of a wound care formulation 100 to form a stable protection and barrier. The wound care formulation 100 comprises a hydrocolloid material 102 includes a hydrated form of a modified metal carbonate 104. The hydrated form of the modified metal carbonate 104 is prepared by processing the modified metal carbonate. The size of the modified metal carbonate is between 500nm and 1000nm. The hydrocolloid material 102 is adaptable to absorbable and non-absorbable configurations. The hydrocolloid material 102 includes the modified metal carbonate. The modified metal carbonate is selected from at least one of a lanthanum carbonate, a cerium carbonate, a samarium carbonate, and a gadolinium carbonate. The modified metal carbonate maintains hydration at or above three water molecules attached to the carbonate. The hydrocolloid material includes methylcellulose, gum and silica In an embodiment, a wound dressing for a patch-based wound care formulation and a gel-based wound care formulation is disclosed. The wound dressing comprises a hydrocolloid material configured to provide a non-absorbable barrier or an absorbable form as required by wound characteristics. The patch and gel configurations are differentiable into the absorbable form and the non-absorbable form based on wound characteristics. The patch-based wound care formulation includes a hydrocolloid-based gel having the hydrocolloid material up to 50% and an emollient up to 30% for non-absorption patches. The gel-based wound care formulation includes the hydrocolloid-based gel having the hydrocolloid material up to 25% and the emollient up to 30% for non-absorption gel. In another embodiment, the hydrocolloid material is configured to be dispensed from a squeezable tube having an applicator tip with gentle fibers. The gentle fibers are being selected from at least one of cotton, fine nylon, and medical-grade synthetic materials. In another embodiment, the hydrocolloid material is configured to be dispensed from the squeezable tube for applying to the challenging surfaces or flexible regions where direct patch retention is difficult. In another embodiment, the wound dressing further comprises essential oils, fragrance, surface tension-reducing material, gum, and flavor. In another embodiment, the hydrocolloid material is configured to be applied in conjunction with wound care products including antibiotics and antiseptics. In another embodiment, the patch-based wound care formulation further comprises a non-sticky patch which is suitable for the areas where direct adhesion is challenging. In another embodiment, the hydrocolloid material is applied as a thin layer (1–2 mm) over the wound surface using gentle pressure, ensuring uniform coverage. Both patch and gel formulations are designed to maintain this thickness range, optimizing wound protection and adherence based on wound characteristics. For oral hard surface wounds (e.g., minor enamel wear, dentin exposure, or cracks), the gel formulation is left undisturbed (e.g., for at least 30 minutes), to ensure optimal adherence and protective barrier formation. The gel does not require rinsing, but rinsing may be performed if necessary, ensuring flexibility in application. For diabetic ulcers and other exudating skin wounds, as well as soft tissue wounds such as oral ulcers or mucosal injuries, the hydrocolloid dressing is maintained based on wound exudate levels to regulate moisture balance. In cases of high exudate secretion (e.g., up to 48 hours), regular inspection is conducted to assess fluid absorption capacity, ensuring sustained wound coverage and minimizing frequent dressing changes. Depending on the wound type and healing progression, the dressing may remain in place for more than 7 days before replacement. The hydrocolloid forms a barrier that prevents microbial contamination, reduces bacterial colonization, and retains moisture. The selection of hydrocolloid material may be based on wound surface characteristics, for example: • For exudating wounds (e.g., diabetic ulcers, pressure sores): An absorbable hydrocolloid formulation is preferred to regulate moisture balance and prevent maceration. • For dry wounds (e.g., minor skin abrasions, teeth surface related, non- exudating oral ulcers): A non-absorbable hydrocolloid formulation provides a stable protective layer without excessive hydration. The hydrocolloid formulation of the present invention incorporates modified metal carbonates that enhances the wound barrier function, reduces bacterial colonization on the barrier, and improves exudate absorption compared to standard hydrocolloid formulations. These advancements address the limitations of existing dressings, promoting a more effective and accelerated healing process. To validate this, a series of comparative tests, explained below, are performed to evaluate the exudate absorption capacity, bacterial adhesion resistance and blister formation of the two formulations: Exudate Absorption Test: The objective of this test is to measure the ability of the hydrocolloid gels to absorb wound exudates, maintaining an optimal healing environment while preventing maceration. Methodology of Exudate Absorption Test: Both carbonate-based and non-carbonate- based hydrocolloid gels are weighed before and after immersion in a simulated wound fluid (saline + albumin + glucose solution). Absorption capacity is measured as the percentage weight increase over 24 hours. Results of Exudate Absorption Test: Carbonate-based gel has 10% higher absorption than baseline (non-carbonate gel). Bacterial Adhesion Test: The objection of this test is to assess the antimicrobial barrier function of the hydrocolloid gels by evaluating bacterial adhesion. Methodology of Bacterial Adhesion Test: Both formulations are coated onto test surfaces. Bacterial cultures are introduced and incubated for 24 - 48 hours. In Bacterial Adhesive Test, samples are stained with crystal violet, and bacterial attachment is quantified using spectrophotometric absorbance. The carbonate-based gel exhibited 12% less bacterial adhesion against a standard hydrocolloid formulation without modified metal carbonates, suggesting improved infection resistance and a stronger antimicrobial barrier. Stable gel network (formed due to optimized particle size and emollient integration) that reduces surface irregularities, making it harder for bacteria to adhere. Blister Formation Test: The objective of this teat is to evaluate the adhesive strength and peeling resistance of hydrocolloid wound dressings by measuring the pressure required to detach the dressing. Higher injection volume = Stronger adhesion Lower injection volume = Weaker adhesion Adhesion tests on dentin discs demonstrated that the carbonate-based hydrocolloid formulation adhered more effectively to dental surfaces compared to the non-carbonate formulation. This is critical for oral wound healing applications, where stable adhesion to mucosal and teeth surfaces is necessary for treatment efficacy Figure 2 illustrates a flowchart of a method for selecting wound care. The method for selecting wound care comprises the step of applying 202 a hydrocolloid material to a wound surface. The hydrocolloid material comprises a modified metal carbonate. The hydrocolloid material is utilized as a standalone component or in combination with antibiotics. The method for selecting wound care comprises the step of creating 204 an environment conducive for healing in oral and skin conditions based on the specific characteristics of the wound. The method for wound care further comprises the step of selecting the absorbability of the hydrocolloid material based on the specific characteristics of the wound. The modified metal carbonate enhances the wound barrier function, reduces bacterial colonization on the barrier, and improves exudate absorption compared to conventional hydrocolloid formulations. The method for wound care comprises applying a hydrocolloid material to a wound surface, wherein the wound surface includes soft tissue wounds, skin wounds, and dental surface wounds such as minor cracks or enamel wear that contribute to sensitivity. The hydrocolloid material provides a protective barrier for both exudating and dry wound surfaces, optimizing healing outcomes. The formulation can be adjusted based on wound characteristics, providing an absorbable or non-absorbable barrier as required for healing progression. In an exemplary embodiment, a non-carbonate formulation includes a gel-based formulations, a mixture of beeswax and silica, wherein the gel-based formulations are prioritized high water content around 32%, which creates a hydrating environment conducive to wound healing. Further, the mixture of beeswax and silica in the range of 27% to 30% provides a protective barrier and potential emollience. Further, a carbonate-based formulation includes an incorporated hydrated modified metal carbonate, wherein the incorporated hydrated modified metal carbonate offers unique functionalities. Further, the carbonate-based formulation includes a hydrocolloid material around 25%, wherein the hydrocolloid material is served as a base and interacts with the modified metal carbonate in the range of 0.15% to 4%. Further, a plurality of lanthanides is also included in the carbonate-based formulation. The plurality of lanthanides includes samarium, cerium, and gadolinium. The plurality of lanthanides provides gel stabilization and wound-healing properties. Furthermore, emollients including beeswax in the range of 25% to 30% provides additional protection. The non- carbonate formulation and the carbonate-based formulation have a core hydrocolloid, both the non-carbonate formulation and the carbonate-based formulation incorporate a plurality of additional functional ingredients essential, wherein the plurality of additional functional ingredients includes oils, fragrance, and surface tension reducers. In addition to silica, gum and methylcellulose, other materials are also incorporated. Other materials include carbopol also known as carbomers, agar-agar, cetearyl alcohol, stearic acid and the like ingredients are capable of being incorporated, depending on the application. For instance, in a plurality of skin care products soothing properties of agar-agar and other like substance is capable of being incorporated. In another exemplary embodiments, formulations for patch and gel applications are provided, wherein a patch-based formulation includes a plurality of non-absorption patches and the hydrocolloid up to 50% are combined with an emollient up to 30%, wherein the emollient provides a protective barrier and promotes wound healing. Further, the patch-based formulation includes an absorption gel. The absorption gel contains water content around 55% and the hydrocolloid is up to 45%. Furthermore, the plurality of non-absorption patches and the absorption gel includes a lanthanide, wherein the lanthanide has a concentration in the range of 0.15% to 4%. Furthermore, a gel-based formulation includes the plurality of non-absorption gels, the hydrocolloid content around 25% and the emollient content is maintained around 30%. The addition in the concentration level as mentioned above ensures a balance between barrier protection and gel consistency. Further, the absorption gel contains water content around 30% and hydrocolloid is up to 25%. Furthermore, the plurality of non-absorption patches and the absorption gel include the lanthanide, wherein the lanthanide has a concentration in the range of 0.15% to 4%. The terms "wound surface" and / or "wound bed" used herein refer to the biological interface where the wound interacts with the external environment and comes into direct contact with the hydrocolloid barrier. Also, the terms "wound surface" and "wound bed" can be used interchangeably without departing from the scope of the present invention. Further, the terms "wound surface" and / or "wound bed" may encompass, but not limited to, the followings: • Skin wounds: It includes abrasions, ulcers, burns, diabetic ulcers, pressure sores, and surgical sites, where wound exudate levels may determine the appropriate hydrocolloid formulation. • Soft tissue wounds: It includes oral mucosal injuries (e.g., gingiva, mucosa, tongue, inner cheeks, palate). Post-surgical sites may also serve as wound surfaces requiring protection and healing support. • Hard tissue (tooth surface related) wounds: It includes minor cracks, enamel abrasions, or dentin exposure contributing to sensitivity that may not require invasive dental treatment but benefit from a protective barrier. The hydrocolloid material is designed to adhere effectively to both moist (exudating) and dry wound surfaces, ensuring an optimized healing environment. The drawings and the forgoing description give examples of embodiments. Those skilled in the art will appreciate that one or more of the described elements / chemicals may well be combined into a single functional element or composition. Alternatively, certain chemicals / elements may be split into multiple functional chemical / elements. Elements / compositions from one embodiment may be added to another embodiment. For example, orders of processes described herein may be changed and are not limited to the manner described herein. Moreover, the actions of any flow diagram need not be implemented in the order shown; nor do all of the acts necessarily need to be performed. Also, those acts that are not dependent on other acts may be performed in parallel with the other acts. The scope of embodiments is by no means limited by these specific examples. Numerous variations, whether explicitly given in the specification or not, such as differences in structure, dimension, and use of material, are possible. The scope of embodiments is at least as broad as given by the following claims. Benefits, other advantages, and solutions to problems have been described above with regard to specific embodiments. However, the benefits, advantages, solutions to problems, and any component(s) that may cause any benefit, advantage, or solution to occur or become more pronounced are not to be construed as a critical, required, or essential feature or component of any or all the claims.

Claims

We Claim:

1. A wound care formulation to form a stable protection and barrier, the wound care formulation comprising: a hydrocolloid material includes a hydrated form of a modified metal carbonate, wherein the hydrated form of the modified metal carbonate is prepared by processing the modified metal carbonate, wherein size of the hydrocolloid material and the modified metal carbonate is between 500nm and 1000nm, and wherein the hydrocolloid material is adaptable to absorbable and non- absorbable configurations, wherein the hydrocolloid material includes the modified metal carbonate, wherein the modified metal carbonate is selected from at least one of a lanthanum carbonate, a cerium carbonate, a samarium carbonate, and a gadolinium carbonate.

2. The formulation as claimed in claim 1, wherein the modified metal carbonate maintains hydration at or above three water molecules attached to the carbonate.

3. The formulation as claimed in claim 1, wherein the hydrocolloid material includes methylcellulose, gum and silica.

4. A wound dressing for a patch-based wound care formulation and a gel-based wound care formulation, the wound dressing comprising: a hydrocolloid material configured to provide a non-absorbable barrier or an absorbable form as required by wound characteristics, wherein the patch and gel configurations are differentiable into the absorbable form and the non-absorbable form based on wound characteristics, wherein the patch-based wound care formulation includes a hydrocolloid-based gel having the hydrocolloid material up to 50% and an emollient up to 30% for non- absorption patches, and wherein the gel-based wound care formulation includes the hydrocolloid-based gel having the hydrocolloid material up to 25% and the emollient up to 30% for non- absorption gel.

5. The wound dressing as claimed in claim 4, wherein the hydrocolloid material is configured to be dispensed from a squeezable tube having an applicator tip with gentle fibers, wherein the gentle fibers are being selected from at least one of cotton, fine nylon, and medical-grade synthetic materials.

6. The wound dressing as claimed in claim 5, wherein the hydrocolloid material is configured to be dispensed from the squeezable tube for applying to the challenging surfaces or flexible regions where direct patch retention is difficult.

7. The wound dressing as claimed in claim 4, wherein the wound dressing further comprises essential oils, fragrance, surface tension-reducing material, gum, and flavor.

8. The wound dressing as claimed in claim 4, wherein the hydrocolloid material is configured to be applied in conjunction with wound care products including antibiotics and antiseptics.

9. The wound dressing as claimed in claim 4, wherein the patch-based wound care formulation further comprises a non-sticky patch which is suitable for the areas where direct adhesion is challenging.

10. A method for selecting wound care, comprising: applying a hydrocolloid material to a wound surface, wherein the hydrocolloid material comprises a modified metal carbonate, wherein the hydrocolloid material is utilized as a standalone component or in combination with antibiotics; creating an environment conducive for healing in oral and skin conditions based on the specific characteristics of the wound; and selecting the absorbability of the hydrocolloid material based on the specific characteristics of the wound.

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