Magnetic-attraction artificial retina and manufacturing method therefor

Abstract

The present application relates to the technical field of medical devices for stimulation, and is related to implantable stimulators. Provided are a magnetic-attraction artificial retina and a manufacturing method therefor. The artificial retina comprises a retinal stimulator and an auxiliary positioner. The retina stimulator comprises an inner magnetic component and an electrode part. The inner magnetic component is arranged on the inner side of the electrode part. The auxiliary positioner comprises an outer magnetic component and a positioner housing. The positioner housing wraps the outer magnetic component, and a curved protrusion is formed on the surface, which is used for being arranged proximal to the eyeball, of the end of the positioner housing that wraps the outer magnetic component. The inner magnetic component and the outer magnetic component can be magnetically attracted to each other. The magnetic-attraction artificial retina can arrange the retinal stimulator on the patient's eyeball by means of magnetic attraction, featuring convenient operation and less damage to the eyeball.

Description

Magnetic artificial retina and manufacturing method thereof Technical Field

[0001] The present application relates to the technical field of medical devices for stimulation, and is related to implantable stimulators, and in particular to a magnetic artificial retina and a method for manufacturing the same. Background Art

[0002] In clinical treatment, it is often necessary to implant artificial medical devices into the human body to facilitate patient recovery or restore certain physiological functions. Artificial retinas, typically including retinal stimulators, can help restore functional vision in patients with vision loss due to age-related or congenital macular retinopathy.

[0003] The stimulation area of ​​the retinal stimulator of the artificial retina usually corresponds to the macula of the retina in the eye and is close to it to obtain a better stimulation effect. Traditional methods of fixing retinal stimulators during implantation include suturing, fixing nails, etc. Among them, the suturing fixation method can easily cause irreversible damage to the thinner and more fragile retinal area, and the suturing operation process is very complicated and has a high surgical risk. The retinal stimulator is fixed to the eyeball tissue using fixing nails. The fixing nails used are usually designed with a cone-shaped nail tip and the bottom area of ​​the cone is larger than the cross-sectional area of ​​the nail rod to prevent the fixing nail from falling out after implantation. The setting of fixing nails can easily cause damage to the retina. At the same time, the fixing nails are usually set at the edge of the stimulation area. In actual operation, the distance between the retinal stimulator and the retinal tissue may be far, affecting the treatment effect. The use of fixing nails will also increase the size of the retinal stimulator, thereby increasing the risk of surgery. Both of the above-mentioned fixing schemes for retinal stimulators make it difficult to remove the retinal stimulator. When the retinal stimulator fails or reaches the end of its life and needs to be replaced, the above-mentioned fixing methods will increase the difficulty and risk of the retinal stimulator replacement surgery.

[0004] On the other hand, in order to achieve better therapeutic effects, it is necessary to make the stimulating electrodes of the retinal stimulator as close to or even fit the retina as possible. Since the wall of the eyeball is an arc surface, the retinal stimulator often needs to use a flexible electrode or a hard electrode that forms a curved surface so that the retinal stimulator can fit the eyeball. Among them, flexible electrodes often use fixed pins to fit the stimulation point tightly to the retina. This method has the disadvantages that the retinal stimulator is prone to damage such as cracking and breaking, cannot be reused, and the number of electrodes is limited. Hard electrodes that form curved surfaces (such as the Utah electrode based on silicon material, "Implantable Neural Microelectrodes". 2020. Vol. 34, No. 1 "Materials Guide") are often difficult to process and have high production costs.

[0005] CN208838247U discloses a silicone-encapsulated artificial retinal implant, which includes a coil base and a neural electrode. The coil base includes a transmission coil and a silicone sheet sleeve that matches the shape of the eyeball, and the transmission coil is encapsulated in the silicone sheet sleeve. The two ends of the silicone sheet sleeve are connected by a bandage, and the silicone sheet sleeve can be fixed to the eyeball through the bandage. The neural electrode includes a silicone arc sleeve and an electrode plate. The electrode plate is arranged in the silicone arc sleeve, one end of the silicone arc sleeve is connected to the side wall of the integrated package, and the other end of the silicone arc sleeve matches the shape of the eyeball and is provided with a groove. One end of the electrode plate extends out of the silicone arc sleeve and is connected to the substrate in the integrated package, and the other end of the electrode plate is provided with a stimulation part that can contact the eyeball, and the stimulation part is located in the groove. A titanium nail hole is provided through the neural electrode, and a titanium nail that can be fixed to the eyeball is inserted into the titanium nail hole.

[0006] The silicone-encapsulated artificial retinal implant disclosed in the aforementioned utility model uses a combination of titanium pins and bandages to secure the neural electrodes (i.e., the retinal stimulator). This method still suffers from the aforementioned drawbacks of using pins to secure the retinal stimulator. Furthermore, the electrode plate of this implant still needs to be formed into a curved surface that matches the shape of the eyeball, which still presents the disadvantages of difficult processing and high production costs. Summary of the Invention

[0007] This application is made in view of the above-mentioned state of the prior art. The purpose of this application is to provide a magnetic artificial retina, which can use a magnetic method to place a retinal stimulator on the patient's eyeball, which is easy to operate and causes less damage to the eyeball.

[0008] The present application also provides a method for manufacturing the above-mentioned magnetic artificial retina.

[0009] The present application provides a magnetic artificial retina, which includes a retinal stimulator and an auxiliary locator. The retinal stimulator includes an inner magnetic part, an electrode part, a chip and a packaging layer. The inner magnetic part is arranged on the inner side of the electrode part. The chip is connected to the electrode part for sending a signal to the electrode part. The packaging layer is connected to the electrode part to encapsulate the inner magnetic part and the chip. The auxiliary locator includes an outer magnetic part and a locator shell. The locator shell wraps the outer magnetic part. A side of one end of the locator shell that wraps the outer magnetic part and is used to be set close to the eyeball is formed with a curved protrusion. The retinal stimulator is used to be set to the retina inside the eyeball, and the auxiliary locator is used to be set to the sclera of the eyeball. The inner magnetic part and the outer magnetic part can be magnetically adsorbed together.

[0010] In at least one possible embodiment, the electrode portion is a hard electrode portion, which includes a hard electrode substrate and a plurality of hard stimulation electrodes, or the electrode portion is a flexible electrode portion, which includes a flexible electrode substrate and a plurality of flexible stimulation electrodes.

[0011] In at least one possible embodiment, the retinal stimulator further comprises an adhesive layer connecting the inner magnetic member to the inner side of the electrode portion, and a stimulator housing connecting the electrode portion to accommodate the encapsulation layer, wherein at least one of the stimulator housing, the adhesive layer, the encapsulation layer and the locator housing is made of a biocompatible material.

[0012] In at least one possible implementation, the inner magnetic component and / or the outer magnetic component are high-temperature resistant magnetized magnetic components.

[0013] In at least one possible embodiment, one or more through holes are formed on the end of the locator housing that does not include the external magnetic member, for connecting the auxiliary locator to the periphery of the eyeball.

[0014] In at least one possible embodiment, the auxiliary locator also includes a support member for maintaining the shape of the auxiliary locator, the support member includes a support member head and a support member tail, the support member head is a planar structure, the external magnetic member is connected to the support member head, and the support member tail is a curved surface structure.

[0015] In at least one possible embodiment, the surface of the inner magnetic part is covered with an inner magnetic part film layer, which is a biocompatible material, and / or the surface of the outer magnetic part is covered with an outer magnetic part film layer, which is a biocompatible material.

[0016] The present application also provides a method for manufacturing a magnetic artificial retina, which includes a retinal stimulator and an auxiliary positioner. The manufacturing of the retinal stimulator includes the following steps: A1: using an adhesive to connect the inner magnetic component to the inner side of the electrode portion; A2: forming a stimulator housing by injection molding, wherein the stimulator housing connects to the electrode portion and accommodates the inner magnetic component. The manufacturing of the auxiliary positioner includes the following steps: B1: providing an outer magnetic component film layer on the surface of the outer magnetic component; B2: forming a positioner housing by injection molding, wherein the positioner housing encloses the outer magnetic component and a support member, wherein one end of the support member is connected to the outer magnetic component.

[0017] In at least one possible embodiment, the method for manufacturing a magnetic artificial retina further includes: before step A1, electrically connecting the chip to the electrode portion; between step A1 and step A2, connecting the electrode portion to the packaging layer.

[0018] In at least one possible embodiment, the method for manufacturing a magnetic artificial retina further includes: before step A1, depositing an inner magnetic component film layer on the surface of the inner magnetic component using physical vapor deposition or chemical vapor deposition.

[0019] The magnetic artificial retina provided in this application can use magnetic attraction to set the retinal stimulator on the patient's eyeball. Compared with the existing method of fixing the retinal stimulator by suturing or fixing nails, this technical solution has a good attachment effect, causes less damage to the eyeball, is more convenient to operate, and is easy to remove the retinal stimulator. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] FIG1 is a schematic structural diagram of an artificial retina according to one embodiment of the present application.

[0021] FIG2 is a schematic structural diagram of an artificial retina from another perspective according to an embodiment of the present application.

[0022] FIG3 is a schematic diagram of the internal structure of an auxiliary positioner according to one embodiment of the present application.

[0023] FIG4 is a schematic diagram of the internal structure of a retinal stimulator according to the first embodiment of the present application.

[0024] FIG5 is a schematic diagram of the internal structure of a retinal stimulator according to a second embodiment of the present application.

[0025] FIG6 is a schematic diagram of the internal structure of a retinal stimulator according to the third embodiment of the present application.

[0026] DESCRIPTION OF NUMERALS 100 Eyeball 10 Retinal stimulator 11 Inner magnetic member 12 Inner magnetic member film layer 13 Stimulator housing 131 Stimulator protrusion 14 Adhesive layer 15 Electrode portion 151 Hard electrode substrate 152 Hard stimulation electrode 153 Flexible electrode substrate 154 Flexible stimulation electrode 16 Chip 17 Packaging layer 18 Lead 20 Auxiliary locator 21 Outer magnetic member 22 Outer magnetic member film layer 23 Support member 231 Support member head 232 Support member tail 24 Locator housing 241 Curved protrusion 25 Through hole 30 Package body 40 Wire 50 Connecting tape DETAILED DESCRIPTION

[0027] The following describes exemplary embodiments of the present application with reference to the accompanying drawings. It should be understood that these specific descriptions are only used to teach those skilled in the art how to implement the present application, and are not intended to exhaust all possible embodiments of the present application, nor to limit the scope of the present application.

[0028] Embodiments of the present application provide a magnetic artificial retina (hereinafter sometimes referred to as an "artificial retina"), as shown in Figures 1 and 2, which may include a retinal stimulator 10 and an auxiliary positioning device 20. The retinal stimulator 10 may be disposed inside an eyeball 100, particularly in the macular region of the inner retina of the eyeball. One end of the auxiliary positioning device 20 may be disposed on the sclera outside the eyeball corresponding to the macular region of the retina.

[0029] As shown in Figures 4 to 6, the retinal stimulator 10 may include an inner magnetic component 11, a stimulator housing 13, an adhesive layer 14, and an electrode portion 15. The inner magnetic component 11 is disposed on the inner side of the electrode portion 15. The adhesive layer 14 can be adhered to and connected to the inner magnetic component 11. The electrode portion 15 can be disposed on a side of the retina of the retina 10 close to the eyeball 100 and can be attached to the retina (particularly the macula). The stimulator housing 13 can be connected to the electrode portion 15 to form a cavity to accommodate the inner magnetic component 11 and other retinal stimulation components.

[0030] Preferably, a stimulator protrusion 131 may be formed on a side of the stimulator housing 13 away from the inner wall of the eyeball to facilitate clamping of the retinal stimulator 10 .

[0031] Regarding the specific structure of the retinal stimulator 10, three specific embodiments are given below.

[0032] First embodiment

[0033] As shown in FIG4 , the retinal stimulator 10 provided in the first embodiment of the present application may further include a chip 16 and an encapsulation layer 17. The electrode portion 15 is a hard electrode portion, which may include a hard electrode substrate 151 and hard stimulation electrodes 152. A plurality of hard stimulation electrodes 152 may be provided on the hard electrode substrate 151.

[0034] The inner magnetic member 11 can be connected to the back side of the chip 16 (the side away from the electrode portion 15 is the back side) via an adhesive layer 14. The chip 16 can be connected to the inner side of the electrode portion 15. For example, the chip 16 can be connected to the electrode portion 15 using a flip-chip solder connection. The chip 16 can send electrical signals to the electrode portion 15 to control the operation of the electrode portion 15 and stimulate the patient's retina to achieve a therapeutic effect or function.

[0035] The packaging layer 17 can be connected to the hard electrode substrate 151, encapsulating the internal magnetic component 11 and the chip 16 between the packaging layer 17 and the hard electrode substrate 151. The packaging layer 17 can be made of glass, ceramic, metal, etc., and can be airtightly packaged by laser welding, metal bonding, brazing, etc.

[0036] Preferably, the adhesive layer 14 may be made of silicone or epoxy resin, and in particular, may be a silicone or epoxy resin with good biocompatibility. It is understood that materials with good biocompatibility can avoid adverse reactions such as allergies and rejection, and increase the service life of the artificial retina. Exemplarily, the biocompatible silicone may be a single-component or two-component silicone, and may be high-temperature curing or room-temperature curing silicone. The biocompatible epoxy resin may be a single-component or two-component epoxy resin, and may be high-temperature curing or room-temperature curing epoxy resin.

[0037] Preferably, the material of the hard stimulation electrode 152 may be a biocompatible material, for example, titanium, gold, platinum, platinum-iridium alloy, iridium oxide, etc.

[0038] Preferably, the chip 16 may be an ASIC chip (Application Specific Integrated Circuit).

[0039] Second embodiment

[0040] The second embodiment of the present application is described below with reference to Figure 5. Components having the same or similar structures or functions as those in the first embodiment are denoted by the same reference numerals, and detailed descriptions of these components are omitted.

[0041] In this embodiment, the internal magnetic component 11 is directly connected to the rigid electrode substrate 151 via the adhesive layer 14, and the chip 16 is wire-bonded to the rigid stimulation electrode 152 via leads 18. Specifically, the surface pads of the chip 16 can be connected to the pads of the rigid stimulation electrode 152 via leads 18. Leads 18 can be made of aluminum wire, gold wire, platinum wire, platinum-iridium alloy wire, or other welding materials permitted for use in active implantable medical devices.

[0042] In this embodiment, the chip 16 may be disposed on the back side of the electrode substrate 151 , parallel to or separated from the inner magnetic member 11 , rather than being disposed between the electrode substrate 151 and the inner magnetic member 11 as in the first embodiment.

[0043] Third embodiment

[0044] The third embodiment of the present application will be described below with reference to Figure 6. Components having the same or similar structures or functions as those in the first embodiment are denoted by the same reference numerals, and detailed descriptions of these components will be omitted.

[0045] In this embodiment, the electrode portion 15 is a flexible electrode portion, and the electrode portion 15 may include a flexible electrode substrate 153 and a flexible stimulation electrode 154. The surface of the internal magnetic component 11 may be covered with an internal magnetic component film layer 12. In this embodiment, the chip 16 may not be provided in the retinal stimulator 10, and the electrode portion 15 may be connected to an external chip using a wire. In this embodiment, a flexible package may be used, and the flexible package layer may be made of an organic polymer material with good biocompatibility, such as polyimide (PI) or polyparaxylene (Parylene).

[0046] It should be understood that some aspects or features of the above-mentioned embodiments may be appropriately combined.

[0047] For example, when the diameter of the eyeball is 24 mm, the radial length of the retinal stimulator 10 may be 5 mm, and the distance between the retinal stimulator 10 and the retina (macular area) of the fundus may be 0.26 mm.

[0048] Furthermore, as shown in Figures 2 and 3, the auxiliary positioner 20 may include an external magnetic member 21, a support member 23, and a positioner housing 24. The external magnetic member 21 can attract the internal magnetic member 11, that is, the magnetic directions of the external magnetic member 21 and the internal magnetic member 11 are the same. After the artificial retina is implanted in the eyeball, the magnetic attraction between the internal magnetic member 11 and the external magnetic member 21 can be used to position the retinal stimulator 10 at a suitable position inside the eyeball 100.

[0049] The support member 23 can help the auxiliary locator 20 maintain its hardness and shape, and may include a support member head 231 and a support member tail 232. The support member head 231 may be a planar structure so that the external magnetic member 21 can be arranged. It is understood that the support member 23 and the external magnetic member 21 may be connected by gluing, or the locator housing 24 may fix the two relative to each other when the locator housing 24 is injection molded. The support member tail 232 may be a curved surface structure, and its shape may be the same as or close to the curvature of the periphery of the eyeball (especially the periphery in the horizontal direction) so that the auxiliary locator 20 can be arranged outside the eyeball 100. The locator housing 24 may wrap the external magnetic member 21 and the support member 23, and the inner side of one end of the locator housing 24 that wraps the external magnetic member 21 (the side that is curved in an arc pointing to the center of the circle is the inner side, that is, the side close to the eyeball is the inner side) may form a curved protrusion 241. It is understood that the curved protrusion 241 can push the wall of the eyeball toward the inside of the eyeball, so that the inner wall of the eyeball (retina) is in contact with or close to the retinal stimulator 10. Using the curved protrusion 241 to push the inner wall of the eyeball inward can effectively fit the retinal stimulator to the retina without using a flexible electrode or a hard electrode with a curved surface, thereby reducing the processing difficulty and production cost of the electrode part.

[0050] It can be understood that the locator housing 24 can be made of a soft material with good biocompatibility, and the support member 23 can support the auxiliary locator 20 to maintain its shape. In this embodiment, the outer shape of the auxiliary locator 20 is roughly an arc with a central angle of 90 degrees. It is not ruled out that the outer shape of the auxiliary locator 20 (especially its locator housing 24) can be roughly an arc with a central angle of 120 degrees, 180 degrees, etc. As shown in Figure 2, one or more through holes 25 (exemplarily, 4 in the figure) can be formed at one end of the housing 24 of the auxiliary locator 20 that does not contain the external magnetic member 21. The through holes can be used to position the auxiliary locator 20 to be connected to the outside of the eyeball 100 by suturing or the like. The through hole 25 may not pass through the support member 23 to avoid exposing the internal components of the auxiliary locator 20. It can be understood that the through hole 25 of the auxiliary locator 20 can be far away from the macular area of ​​the retina, and the aperture of the through hole can be smaller, so compared with the method of using fixing pins to fix the retinal stimulator, it causes less damage to the eyeball (especially near the macular area of ​​the retina), and the surgical difficulty and risk are also lower.

[0051] It is understood that the inner magnetic member 11 and the outer magnetic member 21 can be magnetized magnetic sheets or unmagnetized magnetic sheets. Preferably, the inner magnetic member 11 and / or the outer magnetic member 21 can be magnetized and high-temperature resistant magnetic sheets, such as magnetized strontium ferrite magnetic sheets or magnetized samarium cobalt magnetic sheets, to avoid the subsequent re-magnetization affecting other electronic components and the subsequent high-temperature process on the wall causing demagnetization of the magnetic sheet.

[0052] It is understood that the tissue outside the fundus where the auxiliary locator 20 is located is soft and can accommodate an implant of a certain size. Therefore, the size of the external magnetic member 21 can be flexibly adjusted within a certain range as needed. Furthermore, the size and type of the magnetic member can be adjusted to a wide range, allowing for customized magnetic sheeting tailored to individual patient needs.

[0053] Preferably, the surfaces of the inner magnetic part 11 and the outer magnetic part 21 can be covered with a film layer (especially when the inner magnetic part 11 is not airtightly packaged, a film layer needs to be covered on the outside of the inner magnetic part 11). For example, as shown in Figures 3 and 6, the surface of the inner magnetic part 11 can be covered with an inner magnetic part film layer 12, and the surface of the outer magnetic part 21 can be covered with an outer magnetic part film layer 22. The inner magnetic part film layer 12 and the outer magnetic part film layer 22 can be biocompatible film layers, that is, made of materials with good biocompatibility. The film layer can be a metal film layer, such as titanium (Ti), gold (Au), platinum (Pt), iridium (Ir), etc. Organic material film layers can also be selected, such as polyimide (PI), polyparaxylene (Parylene), polytetrafluoroethylene (PTFE), etc. Providing a film layer with good biocompatibility can avoid adverse reactions such as allergies and rejection, and increase the service life of the artificial retina.

[0054] Preferably, the support member 23 can be made of a material with good biocompatibility, such as a polymer material or a metal material. For example, the polymer material can be polytetrafluoroethylene (PTFE), polyvinyl alcohol (PVA), etc., and the metal material can be titanium (Ti), gold (Au), platinum (Pt), etc.

[0055] Preferably, the stimulator housing 13 and the positioner housing 24 can be made of biocompatible silicone, for example, single-component or two-component silicone, high-temperature curing silicone or room-temperature curing silicone. Alternatively, other suitable biocompatible materials can be used.

[0056] It is understood that, as shown in Figures 1 and 2, the artificial retina of the present application may further include a package 30, which may be connected to the retinal stimulator 10 via a wire 40. The package 30 may also be connected to a connecting band 50, which may at least partially surround the periphery of the eyeball to assist in placing the retinal stimulator 10 and the package 30 on the eyeball. When using the artificial retina, it may also be combined with an external device such as a camera, for example, by wirelessly transmitting image information to the artificial retina via a camera on glasses.

[0057] The embodiments of the present application further provide a method for manufacturing a magnetic artificial retina, wherein the manufacturing of the retinal stimulator 10 may include the following steps:

[0058] A1: Use adhesive to connect the inner magnetic member 11 to the inner side of the electrode portion 15.

[0059] A2: The stimulator housing 13 is formed by injection molding, and the stimulator housing 13 is connected to the electrode part 15 and accommodates the inner magnetic part 11.

[0060] The manufacturing of the auxiliary positioner 20 may include the following steps:

[0061] B1: Depositing the outer magnetic film layer 22 on the surface of the outer magnetic member 21 by physical vapor deposition or chemical vapor deposition. For example, magnetron sputtering equipment, evaporation equipment, etc. can be used.

[0062] B2: The positioner housing 24 is formed by injection molding. The positioner housing 24 wraps the outer magnetic member 21 and the support member 23 . One end of the support member is connected to the outer magnetic member 21 .

[0063] When the electrode portion 15 of the retinal stimulator 10 is a hard electrode portion (hard package), before step A1, the chip 16 can be electrically connected to the electrode portion 15. Between steps A1 and A2, the electrode portion 15 can be connected to the package layer 17.

[0064] When the electrode portion 15 of the retinal stimulator 10 is a flexible electrode portion (flexible package), before step A1, the inner magnetic film layer 12 can be deposited on the surface of the inner magnetic member 11 by physical vapor deposition or chemical vapor deposition.

[0065] It can be understood that based on the specific structure of the aforementioned artificial retina, its manufacturing method may also include the steps of punching a hole in the locator housing 24, placing the retinal stimulator 10 and / or the auxiliary locator 20 into a magnetizer to magnetize the inner magnetic part 11 and the outer magnetic part 21, etc.

[0066] The following briefly describes some of the beneficial effects of the above-mentioned embodiments of the present application.

[0067] The embodiments of the present application provide a magnetic artificial retina and a method for manufacturing the same. This method utilizes a magnetic attraction solution to attach a retinal stimulator to the retina using magnetic attraction. Compared to existing methods of securing retinal stimulators using sutures or pins, this solution offers improved attachment, less damage to the eyeball, more convenient surgical procedures, and ease of removal of the retinal stimulator. Furthermore, the artificial retina utilizes curved protrusions 241 to prop up the inner wall of the eyeball, eliminating the need for flexible or curved rigid electrodes to effectively bond the retinal stimulator to the retina, thereby reducing the processing difficulty and production cost of the retinal stimulator.

[0068] It is understood that in this application, when the number of parts or components is not specifically limited, the number may be one or more, and the term "plurality" herein refers to two or more. Where the number of parts or components is shown in the drawings and / or described in the specification as a specific number, such as two, three, or four, the specific number is generally illustrative and not restrictive, and may be understood as a plurality, i.e., two or more. However, this does not mean that this application excludes the case of one.

[0069] It should be understood that the above embodiments are merely exemplary and are not intended to limit the present application. Those skilled in the art may make various modifications and changes to the above embodiments based on the teachings of the present application without departing from the scope of the present application.

Claims

1. A magnetic artificial retina, characterized in that: It includes a retinal stimulator (10) and an auxiliary positioning device (20), The retinal stimulator (10) includes an inner magnetic part (11), an electrode part (15), a chip (16) and a packaging layer (17). The inner magnetic member (11) is arranged on the inner side of the electrode portion (15), The chip (16) is connected to the electrode portion (15) and is used to send a signal to the electrode portion (15). The encapsulation layer (17) is connected to the electrode portion (15) to encapsulate the inner magnetic member (11) and the chip (16), The auxiliary positioner (20) includes an outer magnetic member (21) and a positioner housing (24). The locator housing (24) wraps the external magnetic member (21), and a curved protrusion (241) is formed on one side of the end of the locator housing (24) wrapping the external magnetic member (21) and being arranged close to the eyeball. The retinal stimulator (10) is used to be arranged on the retina inside the eyeball, and the auxiliary positioner (20) is used to be arranged on the sclera of the eyeball. The inner magnetic part (11) and the outer magnetic part (21) can be magnetically attracted together.

2. The magnetic artificial retina according to claim 1, characterized in that: The electrode portion (15) is a hard electrode portion, and the electrode portion (15) includes a hard electrode substrate (151) and a plurality of hard stimulation electrodes (152), or The electrode portion (15) is a flexible electrode portion, and the electrode portion (15) includes a flexible electrode substrate (153) and a plurality of flexible stimulation electrodes (154).

3. The magnetic artificial retina according to claim 1, characterized in that: The retinal stimulator (10) further comprises: an adhesive layer (14) connecting the inner magnetic member (11) to the inner side of the electrode portion (15), and a stimulator housing (13), the stimulator housing (13) being connected to the electrode portion (15) to accommodate the packaging layer (17), At least one of the stimulator housing (13), the adhesive layer (14), the encapsulation layer (17) and the locator housing (24) is made of a biocompatible material.

4. The magnetic artificial retina according to claim 1, characterized in that: The inner magnetic part (11) and / or the outer magnetic part (21) are high-temperature resistant magnetized magnetic parts.

5. The magnetic artificial retina according to claim 1, characterized in that: One or more through holes (25) are formed on the end of the locator housing (24) that does not include the external magnetic member (21) for connecting the auxiliary locator (20) to the periphery of the eyeball.

6. The magnetic artificial retina according to claim 1, characterized in that: The auxiliary positioner (20) further includes a support member (23) for maintaining the shape of the auxiliary positioner (20). The support member (23) includes a support member head portion (231) and a support member tail portion (232). The support member head (231) is a planar structure, and the external magnetic member (21) is connected to the support member head (231). The support member tail (232) is a curved surface structure.

7. The magnetic artificial retina according to claim 1, characterized in that: The surface of the inner magnetic part (11) is covered with an inner magnetic part film layer (12), and the inner magnetic part film layer (12) is a biocompatible material, and / or The surface of the external magnetic member (21) is covered with an external magnetic member film layer (22), and the external magnetic member film layer (22) is a biocompatible material.

8. A method for manufacturing a magnetic artificial retina, characterized in that: The magnetic artificial retina comprises a retinal stimulator (10) and an auxiliary positioner (20). The manufacturing of the retinal stimulator (10) comprises the following steps: A1: Use adhesive to connect the inner magnetic part (11) to the inner side of the electrode part (15). A2: forming a stimulator housing (13) by injection molding, wherein the stimulator housing (13) is connected to the electrode portion (15) and accommodates the inner magnetic member (11); The manufacturing of the auxiliary positioner (20) comprises the following steps: B1: an outer magnetic member film layer (22) is provided on the surface of the outer magnetic member (21), B2: A positioner housing (24) is formed by injection molding, wherein the positioner housing (24) wraps the external magnetic member (21) and the support member (23), and one end of the support member (23) is connected to the external magnetic member (21).

9. The method for manufacturing a magnetic artificial retina according to claim 8, characterized in that: Also includes: Before step A1, the chip (16) is electrically connected to the electrode portion (15), Between step A1 and step A2, the electrode portion (15) is connected to the encapsulation layer (17).

10. The method for manufacturing a magnetic artificial retina according to claim 8, characterized in that: Before step A1, an inner magnetic component film layer (12) is deposited on the surface of the inner magnetic component (11) by using physical vapor deposition or chemical vapor deposition.

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