Method and apparatus for detecting sealing performance of tubing after installation, and program product

Abstract

A method and apparatus for detecting the sealing performance of tubing after installation. The method for detecting the sealing performance of tubing after installation comprises: when a pump rotates forward, a first tubing pressure sensor P2 detects that the pressure in tubing decreases and a second tubing pressure sensor P1 detects that the pressure in the tubing increases, determining that the tubing is in a sealed state; or when the pump rotates in reverse, the first tubing pressure sensor P2 detects that the pressure in the tubing increases, and the second tubing pressure sensor P1 detects that the pressure in the tubing decreases, determining that the tubing is the sealed state.

Description

Method, device and program product for detecting the sealing performance of pipelines after installation Technical Field

[0001] The present application relates to the field of intelligent medical care, and specifically to a method, device, program product, and computer-readable storage medium for detecting the sealing of a pipeline after installation. Background Art

[0002] As the transplantation of adipose-derived regenerative cells mixed with fat has become a common clinical procedure, a variety of methods for handling fat and adipose-derived regenerative cells have emerged. During the processing of fat and adipose-derived regenerative cells, fluids and fats must be transported through pipelines. Existing methods often require manual judgment when transporting different materials within the pipelines, resulting in a low degree of automation. Summary of the Invention

[0003] To address the above issues, the present application provides a method for detecting the sealing of a pipeline after installation. The pipeline is installed in medical equipment, and the medical equipment includes a first pipeline pressure sensor, a pump, and a second pipeline pressure sensor. The method for determining the sealing of the pipeline by detecting the change in pipeline pressure through the pressure sensor includes:

[0004] When the pump rotates forward, the first pressure sensor of the pipeline detects that the pressure in the pipeline decreases or the second pressure sensor of the pipeline detects that the pressure in the pipeline increases, and the pipeline is determined to be in a sealed state; or when the pump rotates reversely, the first pressure sensor of the pipeline detects that the pressure in the pipeline increases or the pressure of the second pressure sensor of the pipeline decreases, and the pipeline is determined to be in a sealed state.

[0005] The method also includes blockage detection; the blockage detection is that after the test liquid flows through the pipeline, the first pressure sensor of the pipeline detects the pressure of the pipeline liquid inlet port, and the second pressure sensor of the pipeline detects the pressure of the pipeline liquid outlet port. When the pressure of the pipeline liquid outlet port increases or the pressure of the pipeline liquid inlet port decreases, it is determined that the pipeline is blocked; when the pressure remains unchanged, it is determined that the pipeline is in a normal state.

[0006] The medical equipment also includes a photoelectric monitoring module, which consists of an optical sensor, a voltage feedback port, a monitoring port, and a comparator. The pipeline passes through the photoelectric monitoring module, and the photoelectric monitoring module detects whether the pipeline is correctly installed. The optical sensor performs pipeline detection to obtain a feedback voltage, and the feedback voltage is fed back to the voltage feedback port. The comparator then compares the feedback voltage value of the voltage feedback port with the preset threshold of the monitoring port. When the feedback voltage is greater than the preset threshold, it is determined that the pipeline is correctly installed. Otherwise, it is unsuccessful, and a prompt sound and prompt message are used to remind the user to reinstall it.

[0007] The purpose of the present application is to provide a method for automatic fat cleaning, wherein the method performs the above-mentioned pipeline post-installation sealing detection method to obtain a successfully installed and sealed pipeline, comprising:

[0008] Obtain fat aspirates and fat washes;

[0009] The fat extract and the fat washing solution are mixed and shaken, and then allowed to stand and separate to obtain fat and waste liquid;

[0010] The waste liquid is discharged to obtain the washed fat.

[0011] The waste liquid discharge is determined by monitoring the pressure in the waste liquid discharge pipeline to determine whether the waste liquid is completely discharged. When the pressure becomes smaller, it is determined that all the waste liquid is discharged.

[0012] The waste liquid is discharged n times, where n is a natural number greater than or equal to 1, and the completion of the fat cleaning is monitored by detecting the indicators of the waste liquid in the waste liquid discharge pipeline during each discharge process;

[0013] The feedback voltage of the waste liquid in the monitoring waste liquid discharge pipeline is compared with a preset voltage threshold to determine the fat cleaning situation. When the feedback voltage is higher than the preset voltage threshold, the fat cleaning liquid is injected and the next cleaning is performed; when the feedback voltage is lower than the preset voltage threshold, it is determined that the cleaning is completed and the cleaned fat is obtained.

[0014] The method also includes automatic unblocking of blockages, and when blockage occurs during the waste liquid discharge process, automatic unblocking is performed; wherein, when the blockage occurs, the pressure of the discharge pipeline decreases, the discharge of the waste liquid is stopped, and the automatic unblocking procedure is waited for to be executed.

[0015] The automatic dredging includes forward dredging and / or reverse dredging; the forward dredging is performed by flushing the blockage with fat cleaning fluid; the reverse dredging is performed by flushing the blockage with waste fluid.

[0016] The forward dredging is performed by a high-intensity flushing speed, and the reverse dredging is performed by a low-intensity flushing speed.

[0017] The purpose of the present application is to provide a method for automatically obtaining fat matrix components, the method comprising: obtaining fat and fat decomposition liquid and mixing them to obtain a mixed liquid containing fat matrix components; the fat is the fat cleaned by the above-mentioned fat cleaning method;

[0018] The mixed liquid containing the fat matrix component is allowed to stand for stratification, wherein the upper layer is waste liquid and the lower layer is liquid containing the fat matrix component;

[0019] The liquid containing the fat matrix component is extracted to obtain the fat matrix component.

[0020] The extraction includes M times, each time extracting N milliliters, where M is a natural number greater than or equal to 1 and N is a natural number less than 85. When the single extraction volume meets a preset threshold, the extraction is paused and the extracted fat matrix components are waited for to be delivered to a cache. When the delivery of the fat matrix components is completed, the next extraction is performed. When the single extraction volume does not meet the preset threshold but the extraction automatically ends, the extracted fat matrix components are delivered to the cache, and the extraction process ends to obtain the fat matrix components.

[0021] The extraction also includes fat matrix component detection. Each time the extraction is performed, it is detected whether there is fat matrix component in the extraction pipeline. When the detection result is fat matrix component, the extraction is continued; when the detection result is waste liquid, the extraction is terminated.

[0022] The fat matrix component detection is to determine the type of liquid in the pipeline by monitoring the real-time voltage obtained by the extraction pipeline. When the real-time voltage is less than a preset voltage, it is determined to be a fat matrix component and the extraction continues. When the real-time voltage is greater than the preset voltage, it is determined to be waste liquid and the extraction ends.

[0023] The method further comprises pumping back the waste liquid. After the fat matrix components are extracted, waste liquid exists in the extraction pipeline, and the waste liquid is pumped back, wherein the waste liquid is pumped back at a low speed.

[0024] The method further includes automatically washing the fat matrix components, washing the fat matrix components to obtain washed fat matrix components, wherein the washing is divided into two steps: enrichment and resuspension; the fat matrix components in the fat matrix component liquid are extracted by the enrichment, and the fat matrix components are washed by resuspension, and the enrichment and resuspension are performed in sequence, wherein the enrichment is repeated k times and the resuspension is repeated m times to obtain the washed fat matrix, where k and m are natural numbers greater than 1.

[0025] The enrichment and extraction separates the fat matrix component and waste liquid in the fat matrix component liquid by high-speed rotation, and the waste liquid is discharged through a pipeline to obtain the fat matrix component.

[0026] The number of enrichment times in the method is equal to the number of extraction times in the method for automatically obtaining fat matrix components. The resuspension includes two parts: shaking and centrifugation. The specific steps are:

[0027] Step 1: Get fat cleaning solution;

[0028] Step 2: The fat washing liquid is collected and enriched with the fat matrix components, and then subjected to oscillation and washing to obtain a mixed liquid; wherein the oscillation and washing are performed by rotating at a low speed;

[0029] Step 3: Separate the washed fat matrix component and the washing waste liquid in the mixed solution by centrifugation, and discharge the washing waste liquid through a pipeline to obtain the washed fat matrix component.

[0030] The purpose of the present application is to provide a computer program product, which includes a computer program or instructions, and the computer program or instructions are executed by a processor to implement the above-mentioned method for detecting the sealing of the pipeline after installation, or to implement the above-mentioned method for automatic fat cleaning, or to implement the above-mentioned method for automatically obtaining fat matrix components.

[0031] The purpose of the present application is to provide a computer device, which includes a memory, a processor and a computer program or instructions stored on the memory, wherein the computer program or instructions are executed by the processor to implement the above-mentioned method for detecting the sealing of the pipeline after installation, or to implement the above-mentioned method for automatic fat cleaning, or to implement the above-mentioned method for automatically obtaining fat matrix components.

[0032] The purpose of the present application is to provide a computer-readable storage medium having a computer program or instructions stored thereon, wherein the computer program or instructions are executed by a processor to implement the above-mentioned method for detecting the sealing of the pipeline after installation, or to implement the above-mentioned method for automatic fat cleaning, or to implement the above-mentioned method for automatically obtaining fat matrix components.

[0033] The purpose of this application is to provide a device for fat cleaning, fat matrix acquisition and cleaning, and pipeline sealing detection after installation, including:

[0034] A pipeline to be tested, wherein the pipeline to be tested is composed of M interconnected pipeline paths, where M is a natural number greater than 1; a pump passing through the pipeline to be tested and used to provide power;

[0035] A pressure detection module, comprising L pressure sensors, where L is a natural number greater than or equal to 2, wherein the pipeline passes through the pressure detection module, wherein the pipeline passes through a first pipeline pressure sensor, a pump, and a second pipeline pressure sensor in sequence, wherein gas in the pipeline flows as the pump rotates, and the tightness of the pipeline is determined by detecting changes in pipeline pressure through the pressure sensors, including: when the pump rotates forward, the pipeline first pressure sensor detects that the pressure in the pipeline decreases and the pipeline second pressure sensor detects that the pressure in the pipeline increases, thereby determining that the pipeline is in a sealed state; or when the pump rotates reversely, the pipeline first pressure sensor detects that the pressure in the pipeline increases and the pressure in the pipeline second pressure sensor decreases, thereby determining that the pipeline is in a sealed state;

[0036] The pressure detection module also includes a blockage detection function. The blockage detection function is that after the test liquid flows through the pipeline, the first pressure sensor of the pipeline detects the pressure of the pipeline liquid inlet port, and the second pressure sensor of the pipeline detects the pressure of the pipeline liquid outlet port. When the pressure of the pipeline liquid outlet port increases or the pressure of the pipeline liquid inlet port decreases, the pipeline is determined to be blocked; when the pressure remains unchanged, the pipeline is determined to be in a normal state.

[0037] The photoelectric monitoring module includes an optical sensor, a voltage feedback port, a monitoring port, and a comparator. The photoelectric monitoring module is used to detect whether the pipeline is correctly installed. The pipeline passes through the photoelectric monitoring module. The optical sensor performs pipeline detection to obtain a feedback voltage, and the feedback voltage is fed back to the voltage feedback port. The comparator then compares the feedback voltage value of the voltage feedback port with the preset threshold value of the monitoring port. When the feedback voltage is greater than the preset threshold value, it is determined that the pipeline is correctly installed. Otherwise, it is unsuccessful, and a prompt sound and prompt message are used to remind the user to reinstall it.

[0038] The pipeline to be tested includes a liquid inlet pipeline and a liquid discharge pipeline. The device also includes a fat cleaning container. The liquid inlet pipeline and the liquid discharge pipeline are connected to the fat cleaning container. The path for transporting liquid in the pipeline to be tested also includes a stop valve. The liquid inlet pipeline includes a first stop valve and a fifth stop valve, and the path of the liquid discharge pipeline includes a second stop valve and a fourth stop valve. The pump is located between the first stop valve and the fifth stop valve of the liquid inlet pipeline, and the pipeline through which the fat cleaning liquid passes passes through the first stop valve, the pump, and the fifth stop valve in sequence; the power pump is located between the second stop valve and the fourth stop valve of the liquid discharge pipeline; the pipeline through which the waste liquid passes passes through the second stop valve, the pump, and the fourth stop valve in sequence; the liquid discharge pipeline passes through the photoelectric monitoring module, and the liquid discharge pipeline through which the waste liquid passes passes through the photoelectric control module, the second stop valve, the pump, and the fourth stop valve in sequence;

[0039] After the photoelectric monitoring module detects that the pipeline is correctly installed and the pressure sensor determines that the pipeline is in a sealed state, the fat is injected into the fat cleaning container and the fat cleaning liquid is input through the liquid inlet pipeline. The fat cleaning container is vibrated and shaken to clean the fat to obtain the cleaned fat and cleaning waste liquid. The cleaning waste liquid is discharged through the drainage pipeline and the waste liquid feedback voltage when the waste liquid flows through the drainage pipeline is detected by the photoelectric monitoring module to determine whether the fat is cleaned; wherein, the waste liquid feedback voltage of the voltage feedback port is compared with the waste liquid monitoring threshold of the monitoring port by a comparator. When the waste liquid feedback voltage is greater than the waste liquid monitoring threshold, it is determined that the fat is not cleaned, and the fat cleaning liquid is input through the pipeline to continue the next cleaning. Otherwise, it is determined that the fat is cleaned and the current cleaning is the final cleaning.

[0040] The device also includes a device for unblocking blockages. During the waste liquid discharge process, the first pressure sensor of the pipeline detects that the pressure of the discharge pipeline has decreased and the pump stops providing pressure to discharge the waste liquid. The device enters the steps of forward unblocking and / or reverse unblocking; when the unblocking is forward unblocking, the stop valve on the liquid inlet pipeline is opened to form a liquid inlet passage, and then the pump is started to provide pressure to pressurize the fat cleaning liquid to flush the mesh filter to complete the unblocking; when the unblocking is reverse unblocking, the pump is started to provide pressure to pressurize the waste liquid back to reversely flush the mesh filter to complete the unblocking.

[0041] The pipeline also includes a liquid extraction pipeline, through which fat matrix components are output. When the device extracts fat matrix, the photoelectric control module is located in the liquid extraction pipeline path. The fat matrix passes through the photoelectric control module, the second stop valve, the pump, and the sixth stop valve in the liquid extraction pipeline in sequence. The comparator compares the real-time voltage with the preset voltage to determine the type of liquid in the pipeline. When the feedback voltage is lower than the preset voltage threshold, it is determined to be fat matrix components. When the feedback voltage is higher than the preset voltage threshold, it is determined to be waste liquid.

[0042] The device also includes a buffer container and a waste liquid container, wherein the extracted fat matrix component is stored in the buffer container, and the discharged waste liquid is stored in the waste liquid container; the buffer container is a centrifugal chamber, including a static module, and the static module is composed of a liquid inlet, a liquid outlet, and an in-chamber delivery pipeline. The fat matrix component liquid enters the centrifugal chamber through the liquid inlet and enters the interior of the centrifugal chamber along the in-chamber delivery pipeline;

[0043] The centrifugal chamber further comprises a rotating module, the rotating module comprising a rotating central axis, a centrifugal chamber, and a storage area; N centrifugal chambers are connected with the rotating central axis as the center, and each end of the N centrifugal chambers is connected to a storage area, where N is a natural number greater than or equal to 1; wherein the centrifugal chambers are connected to the storage area at an inclined angle; a delivery pipeline of the static module is connected to the N centrifugal chambers, and the fat matrix component liquid is delivered to the centrifugal chambers through the delivery pipeline of the static module, and the fat matrix component liquid is cleaned by rotating the centrifugal chambers in the rotating module;

[0044] The pipeline also includes a liquid outlet pipeline, which is connected to the liquid outlet. The waste liquid in the cabin is discharged through the liquid outlet pipeline. The waste liquid in the cabin passes through the third stop valve, the pump, and the fourth stop valve in sequence to the waste liquid container through the liquid outlet pipeline.

[0045] The cleaning includes enrichment, through which separated fat matrix components and waste liquid in the cabin are obtained. The waste liquid in the cabin is transported to the liquid outlet through a transport pipeline and then discharged through the liquid outlet pipeline to obtain the fat matrix components.

[0046] The cleaning further includes resuspending the fat matrix component. The resuspending step comprises: first delivering a fat cleaning liquid into the interior of the centrifugal chamber through the liquid inlet and the in-chamber delivery pipeline, oscillating and cleaning the fat matrix component to obtain cleaned fat matrix components and cleaning waste liquid, then centrifuging to collect the fat matrix components into a storage area connected to the centrifugal chamber to obtain the cleaned fat matrix components, and discharging the cleaning waste liquid through the liquid outlet and the liquid outlet pipeline.

[0047] Advantages of this application:

[0048] 1. This application provides a pipeline sealing detection method in the process of processing fat and adipose-derived regenerative cells. This method can detect sealing problems at pipeline joints in real time and efficiently, reminding users to check in time to avoid transportation failure or contamination of medical materials during transportation. It can also facilitate the detection of whether the pipeline is installed correctly, laying the foundation for subsequent medical material operations. The method of detecting whether the pipeline is blocked before transportation can ensure the normal operation of the pipeline, avoid waste of transported materials, circumvent transportation failures, and especially save medical time when transporting medical materials.

[0049] 2. This system provides a standardized process and device for automated fat cleaning, resolving the issues of inconsistent methods and processes. Automated cleaning reduces the potential for contamination compared to manual cleaning, saving human resources and time, and improving fat usability. Furthermore, this standardized process and device ensures that each batch of fat is cleaned in the same environment, addressing the issue of uneven fat properties. It also effectively addresses the issue of blockage that can occur during automated fat cleaning.

[0050] 3. An automated method for material extraction is proposed, avoiding manual errors and contamination during operation, reducing labor costs and time. Specifically, voltage detection is used to distinguish between fat matrix components and waste liquid. This method can effectively identify the type of liquid being transported within the pipeline, with high sensitivity and timely feedback, facilitating timely control of the delivery of fat matrix components and reducing the probability of waste liquid being carried along. Furthermore, a small number of extractions are used to extract the fat matrix components, with the liquid type detected during each extraction. This method ensures that the first n extractions contain fat matrix components, with waste liquid only present in the final extraction. This allows for the focus to be on the final extraction, rather than the entire delivery process, reducing the probability of waste liquid contaminating the fat matrix components. BRIEF DESCRIPTION OF THE DRAWINGS

[0051] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present application. For those skilled in the art, other drawings can be obtained based on these drawings without creative work.

[0052] FIG1 is a schematic diagram of the installation of a stop valve, a pump, a pressure sensor, and an optical detection module in a pipeline according to an embodiment of the present application;

[0053] FIG2 is a schematic diagram of an apparatus for fat cleaning, fat matrix acquisition, and cleaning provided in an embodiment of the present application; FIG2 is a schematic diagram of a test liquid testing pipeline and a liquid inlet pipeline path and a liquid discharge pipeline path during fat cleaning;

[0054] FIG3 is a schematic diagram of feedback voltage of a pipeline sample provided in an embodiment of the present application;

[0055] FIG4 is a schematic flow chart of a method for automatic fat cleaning according to an embodiment of the present application;

[0056] FIG5 is a schematic diagram of an automatic fat cleaning system provided in an embodiment of the present application;

[0057] FIG6 is a schematic diagram of an optical detection principle provided in an embodiment of the present application;

[0058] FIG7 shows the voltage response change of the optical sensor during the liquid discharge process provided by an embodiment of the present application;

[0059] FIG8 is a schematic flow chart of a method for automatically obtaining fat matrix components according to an embodiment of the present application;

[0060] FIG9 is a schematic diagram of a system for automatically obtaining fat matrix components provided in an embodiment of the present application;

[0061] FIG10 is a schematic diagram of the liquid extraction pipeline path and the liquid discharge pipeline path of the waste liquid in the chamber during fat matrix extraction provided in an embodiment of the present application;

[0062] FIG11 is a schematic diagram of real-time voltage changes during the delivery of fat matrix components according to an embodiment of the present application. DETAILED DESCRIPTION

[0063] In order to enable those skilled in the art to better understand the solution of the present application, the technical solution in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings in the embodiments of the present application.

[0064] In some of the processes described in the specification and claims of this application and the above-mentioned figures, multiple operations that appear in a specific order are included, but it should be clearly understood that these operations may not be executed in the order in which they appear in this document or may be executed in parallel. The serial numbers of the operations, such as S101, S102, etc., are only used to distinguish between different operations, and the serial numbers themselves do not represent any order of execution. In addition, these processes may include more or fewer operations, and these operations may be executed in sequence or in parallel. It should be noted that the descriptions of "first", "second", etc. in this document are used to distinguish different messages, devices, modules, etc., and do not represent a sequential order, nor do they limit "first" and "second" to being different types.

[0065] An embodiment of the present application provides a method for detecting the sealing of a pipeline after installation, wherein the pipeline is installed in medical equipment, and the medical equipment includes a first pipeline pressure sensor, a pump, and a second pipeline pressure sensor. As shown in Figure 1, the gas in the pipeline flows following the rotation of the pump, wherein the method for determining the sealing of the pipeline by detecting the change in pipeline pressure by the pressure sensor includes: when the pump rotates forward, the first pressure sensor detects that the pressure in the pipeline decreases or the second pressure sensor detects that the pressure in the pipeline increases, and determines that the pipeline is in a sealed state; or when the pump rotates reversely, the first pressure sensor detects that the pressure in the pipeline increases or the pressure of the second pressure sensor decreases, and determines that the pipeline is in a sealed state.

[0066] In one embodiment, when the airflow or liquid flows in the pipeline, it passes through the pipeline second pressure sensor, the pump, and the pipeline first pressure sensor in sequence; when the airflow or liquid flows in the pipeline in the reverse direction, it passes through the pipeline first pressure sensor, the pump, and the pipeline second pressure sensor in sequence.

[0067] In one embodiment, the forward rotation causes the airflow or liquid in the pipeline to flow from the liquid inlet port to the liquid outlet port; the reverse rotation causes the airflow or liquid in the pipeline to flow from the liquid outlet port to the liquid inlet port.

[0068] In one embodiment, the method also includes blockage detection; the blockage detection is that after the test liquid flows through the pipeline, the first pressure sensor of the pipeline detects the pressure of the pipeline liquid inlet port, and the second pressure sensor of the pipeline detects the pressure of the pipeline liquid outlet port, and determines whether the pipeline is blocked by detecting the pressure change. When the pressure of the pipeline liquid outlet port increases or the pressure of the pipeline liquid inlet port decreases, it is determined that the pipeline is blocked; when the pressure remains unchanged, it is determined that the pipeline is in a normal state.

[0069] In one embodiment, the method first performs pipeline sealing detection and then performs pipeline blockage detection.

[0070] In one embodiment, when the method is used to detect pipeline sealing, gas (airflow) / air flows in the pipeline, and when the method is used to detect pipeline blockage, liquid / water flows in the pipeline.

[0071] In one embodiment, the first pressure sensor detects the liquid inlet port of the pipeline, and the liquid inlet port includes N liquid inlets; the second pressure sensor detects the liquid outlet port of the pipeline, and the liquid outlet port includes N liquid outlets, where N is a natural number greater than or equal to 1.

[0072] In one embodiment, the medical equipment also includes a photoelectric monitoring module, which is composed of an optical sensor, a voltage feedback port, a monitoring port, and a comparator. The pipeline passes through the photoelectric monitoring module, and the photoelectric monitoring module detects whether the pipeline is correctly installed. The optical sensor performs pipeline detection to obtain a feedback voltage, and the feedback voltage is fed back to the voltage feedback port. The comparator then compares the feedback voltage value of the voltage feedback port with the preset threshold of the monitoring port. When the feedback voltage is greater than the preset threshold, it is determined that the pipeline is correctly installed. Otherwise, it is unsuccessful, and a reminder to reinstall is given through a prompt sound and prompt message.

[0073] In another embodiment, the method simultaneously detects pipeline sealing and pipeline blockage. In another embodiment, the method detects pipeline sealing using a pressure sensor, then detects whether the pipeline is correctly installed using a photoelectric monitoring module, and then detects pipeline blockage using a pressure sensor.

[0074] In another embodiment, the method detects pipeline tightness using a pressure sensor, detects correct pipeline installation using a photoelectric monitoring module, and then detects pipeline blockage using a pressure sensor. In another embodiment, the method first detects correct pipeline installation using a photoelectric monitoring module, then detects pipeline tightness using a pressure sensor, and then detects pipeline blockage using a pressure sensor. In one embodiment, the preset threshold is set to a no-load voltage V+0.15VDC, where the no-load voltage V is the initial voltage when the optical sensor is not installed in the pipeline.

[0075] In a specific embodiment, the pipeline is installed in two pressure sensors (P1, P2). When the pipeline is blocked or leaking, the pressure sensors can monitor the pressure changes in the pipeline, and then the system can determine which part of the pipeline is blocked or leaking.

[0076] In one embodiment, the first pressure sensor serves as P2 and the second pressure sensor serves as P1.

[0077] In one embodiment, the pressure sensor housing is designed to accommodate a pipeline. A contact is located where the pipeline is mounted, and a pressure sensor is connected to the contact. The pressure applied to the contact is proportional to the voltage output by the pressure sensor. When the pipeline is correctly installed for the first time, the contact is subjected to a certain pressure, and the pressure sensor outputs a corresponding voltage. When the pipeline (or hose) leaks or becomes clogged, the internal air pressure changes, causing the pipeline to expand or contract, and the corresponding output voltage increases or decreases, thereby determining whether the pipeline is leaking or clogged. In one specific embodiment, a medical device includes a photoelectric control module, a pipeline, and a central processing unit. The light-emitting diode of the optical sensor in the photoelectric control module generates a fixed 890nm light source. When substances of different optical densities pass through the module, the module monitors the different substances in real time and generates a feedback voltage. This feedback voltage is positively correlated with the optical density of the substance. The feedback voltage value is compared with a preset threshold value of the monitoring port, and the comparison result is transmitted to the device's central processing unit to determine the different substances in the pipeline.

[0078] In one embodiment, the photoelectric control module is used to determine the substance in the pipeline. When determining whether the pipeline is correctly installed, the substance in the pipeline includes one or more of the following: air, clean water, and sodium lactate Ringer's solution.

[0079] In one embodiment, the pipeline installation monitors:

[0080] 1.1) When the optical sensor is empty (i.e., unloaded), the no-load response voltage is Vnoload. When an empty pipe is installed in the optical sensor, the sensor's response voltage rises significantly. Therefore, to monitor an empty pipe, the empty pipe monitoring threshold simply needs to be set above the no-load response voltage. However, due to variations in light intensity, contamination in the optical path, or other factors, the optical sensor's no-load response voltage can increase over time. Therefore, after experimental research, the empty pipe monitoring port VP9 has been set to Vnoload + 0.15V.

[0081] 1.2) When installing consumables, the device prompts you to properly install the empty pipe on the optical sensor. A properly installed empty pipe and the correct installation method will trigger real-time voltage feedback VP2>VP9 (i.e., VP2>Vnoload+0.15V), indicating that the pipe is correctly installed in the optical sensor. VP2 and VP9 are two ports: VP2 is the real-time voltage feedback port, and VP9 is the monitoring port, which is Vnoload+0.15V.

[0082] In a specific embodiment, when there is no substance in the optical sensor (i.e., no-load), the no-load feedback voltage value is approximately 0.4VDC (subject to actual conditions). When an empty pipeline is installed in the optical sensor, the feedback voltage value of the optical sensor will rise. Therefore, for monitoring the empty pipeline, it is only necessary to set the empty pipeline monitoring threshold to be greater than the no-load feedback voltage value. However, due to changes in the intensity of the light-emitting diode, stains in the optical path, or other reasons, the no-load feedback voltage value of the optical sensor will rise over time. Therefore, if the empty pipeline monitoring threshold is set to be only slightly larger than the no-load feedback voltage, the system may mistakenly detect that a disposable consumable has been loaded and instruct the user to remove it. This will cause trouble to the user. By raising the empty pipeline monitoring threshold to the recommended value of 0.150VDC higher than the no-load response voltage value, the possibility of such an error will be significantly reduced.

[0083] Figure 3 shows the optical sensor's feedback values ​​for hundreds of pipe samples from five different batches. These values ​​range from a minimum of 0.598 VDC to a maximum of 2.072 VDC. Because the measured no-load feedback voltage is 0.436 VDC, the corresponding voltage response value varies from a minimum increment of 0.162 VDC to a maximum increment of 1.636 VDC. Furthermore, the optical density of empty pipes varies significantly, and the empty pipe monitoring threshold is only used to determine whether a pipe is installed, so voltage accuracy requirements are not very high. Therefore, a value 0.150 VDC higher than the no-load response voltage (close to 0.162 VDC) was selected as the empty pipe monitoring threshold to satisfy every sample tested while reducing the probability of false detections. Among them, the test pipeline in Figure 3 includes 1) real-time aging, batch 101607-07, 2) new bulk sample, end of roll, batch 101607-02, 3) new bulk sample, beginning of roll, batch 110707-01, 4) products that have been sterilized, accelerated aging, and transport tested, and 5) real-time aging, batch 101607-06.

[0084] The statistical graph shows that the optical sensor output voltage varies significantly for empty tubing of different types and batches. However, the only function of an empty tubing is to determine whether the tubing is installed. The optical sensor's other two functions (waste liquid detection and lipid detection) both occur in tubing containing lactated Ringer's solution. As can be seen from the graph, the addition of lactated Ringer's solution improves the optical clarity of the tubing, resulting in very small and similar output voltages for various tubing types. Therefore, the impact of different tubing types and batches on the system is minimal.

[0085] In a specific embodiment, the debugging parameters of the photoelectric monitoring module are shown in Table 1:

[0086] Table 1 Empty pipeline debugging parameters

[0087] In a specific embodiment, the medical equipment includes pipelines for transporting various liquids (materials); the pipelines are divided into liquid inlet pipelines and liquid discharge pipelines, and the liquid is input through the liquid inlet pipeline and discharged through the liquid discharge pipeline, as shown in FIG2 .

[0088] Peristaltic pump: can drive liquid / substance to flow in the pipeline, with three speed modes.

[0089] In a specific embodiment, a blockage test is performed after a sealing test is performed on the pipeline. The pipeline also includes N stop valves for controlling the flow of materials in the pipeline, where N is a natural number greater than or equal to 1; the positions of the pressure sensors P1 (the second pressure sensor of the pipeline) and P2 (the first pressure sensor of the pipeline) are shown in Figure 2. The pipeline passes through the peristaltic pump and is distributed on both sides of the peristaltic pump. The pipeline through which P1 passes is connected to one side of the pipeline passing through the peristaltic pump, and is connected to the pipeline passing through the fourth stop valve to form a three-way intersection No. 4. The pipeline through which P2 passes is connected to the other side of the pipeline passing through the peristaltic pump, and is connected to the pipeline passing through the first stop valve to form a three-way intersection No. 1; the rotation of the peristaltic pump provides power for material transportation.

[0090] In a specific embodiment, the pipeline passing through the peristaltic pump and connected to the pressure sensor P1 also includes a fifth stop valve on one side. The pipeline passing through the fifth stop valve is connected to the pipeline passing through the peristaltic pump to form a No. 5 three-way junction. The pipeline passing through the peristaltic pump first passes through the No. 5 three-way junction and then passes through the No. 4 three-way junction.

[0091] In one embodiment, the pipeline through which the first stop valve and the fifth stop valve pass is a liquid inlet pipeline.

[0092] In one embodiment, the pipeline through which the second stop valve and the fourth stop valve pass is a drainage pipeline.

[0093] In one embodiment, the photoelectric control module and the second shut-off valve are located in the same pipeline.

[0094] In a specific embodiment, the pipeline passing through the peristaltic pump pipeline and the above-mentioned No. 1 three-way junction also includes a second stop valve, and the pipeline passing through the second stop valve is connected to the pipeline passing through the peristaltic pump at the No. 2 three-way junction.

[0095] In a specific embodiment, the pipeline is first installed and tested by the photoelectric monitoring module to see if the installation is successful. Then, the pipeline sealing test and the blockage test are performed in sequence. For the sealing test:

[0096] With the first stop valve open and the others closed, set the pump speed to "low-speed reverse" (direction of airflow within the pipeline from the liquid outlet to the liquid inlet). If there is no leakage between the regional pipelines on the side of the pipeline passing through the peristaltic pump and connected to P1, the pressure sensor P1 should detect pressure (pressure decreases). Otherwise, it is considered that the pipeline has a leak, and the system will prompt the user to check and confirm the leak. The regional pipeline is the connecting regional pipeline formed by the pipeline passing through the peristaltic pump, the pipeline passing through P1, the pipeline passing through the fourth stop valve, and the pipeline passing through the fifth stop valve.

[0097] Open the first stop valve and close the others. Set the pump speed to "High-Speed ​​Forward" (the airflow direction in the pipeline is from the liquid inlet to the liquid outlet). If there is no leakage in the interconnected regional pipeline connected to P1, the pressure sensor P1 should detect pressure (increase in pressure). Otherwise, it is considered that there is a leak in the pipeline, and the system will prompt the user to check and confirm the leak. The regional pipeline is the interconnected regional pipeline formed by the pipeline passing through the peristaltic pump, the pipeline passing through P1, the pipeline passing through the fourth stop valve, and the pipeline passing through the fifth stop valve.

[0098] With the fifth stop valve open and the others closed, set the pump speed to "High-Speed ​​Forward." If there's no leakage between the regional pipelines on the side connected to P2 and the pipeline passing through the peristaltic pump, the pressure sensor P2 should detect a pressure drop. Otherwise, it's considered a leak, and the system will prompt the user to check and confirm the leak. The regional pipeline is the interconnected regional pipeline formed by the pipeline passing through the peristaltic pump, the pipeline passing through P2, the pipeline passing through the first stop valve, and the pipeline passing through the second stop valve.

[0099] With the fifth shutoff valve open and the others closed, set the pump speed to "low speed reverse." If there is no leakage in the interconnected regional pipeline connected to P2, the pressure sensor P2 should detect pressure (increase in pressure). Otherwise, it is considered a pipeline leak, and the system will prompt the user to check and confirm the leak. The regional pipeline is the interconnected regional pipeline formed by the pipeline passing through the peristaltic pump, the pipeline passing through P2, the pipeline passing through the first shutoff valve, and the pipeline passing through the second shutoff valve.

[0100] In a specific embodiment, when detecting consumable blockage, the device needs to extract liquid from the sodium lactate Ringer's bag through the liquid inlet pipeline. The pressure sensor P2 will continuously monitor the pressure in the pipeline at the connection between the pipeline puncture device and the sodium lactate Ringer's bag. If the pressure sensor P2 detects the pressure of the pipeline at this time (the pressure decreases), it may be because the protective cover of the puncture device has not been removed, or the puncture device has not completely penetrated the sodium lactate Ringer's bag, or the liquid in the sodium lactate Ringer's bag has been used up. The system will prompt the user to check and confirm the above situation.

[0101] In one specific embodiment, when detecting consumable blockage, the system adds a sodium lactate Ringer's bag to the processing tank via the inlet line. Pressure sensor P1 continuously monitors the pressure within the processing tank's water inlet. If pressure sensor P1 detects an increase in pressure (increased pressure), it could indicate a blockage or kink in the processing tank's water inlet line. The system prompts the user to check and confirm the presence of the blockage.

[0102] In one specific embodiment, when detecting a consumable blockage, the system needs to transfer the lactated Ringer's solution or waste liquid from the treatment tank through the drainage pipeline. Pressure sensor P2 will continuously monitor the pressure in the pipeline at the treatment tank outlet. If pressure sensor P2 detects a decrease in pressure (a decrease in pressure), it may be that there is a blockage or kink in the pipeline at the treatment tank outlet. The system will prompt the user to check and confirm the above situation.

[0103] In one specific embodiment, when detecting consumable blockage, the system needs to drain waste liquid into a waste liquid bag through the drainage pipeline. If the pressure sensor P1 detects an increase in pressure in the pipeline, it may be that the pipeline at the waste liquid bag inlet is blocked, kinked, or the waste liquid bag clamp is blocking the pipeline. The system will prompt the user to check and confirm the above conditions.

[0104] In one embodiment, the pipeline in the present invention is a consumable hose, which is a disposable consumable. The disposable pipeline ensures that the material in the pipeline is not contaminated when the medical equipment performs medical tasks, and compared with reusable medical equipment pipelines, it can avoid cross-infection problems between different patients. Therefore, the medical equipment of the present invention needs to perform a pipeline installation step before use, and then the present invention uses a photoelectric monitoring module to detect whether the pipeline is successfully installed.

[0105] FIG4 is a schematic diagram of a method for automatic fat cleaning according to an embodiment of the present application, comprising:

[0106] S101: Obtaining fat extract and fat washing solution;

[0107] In one embodiment, the fat obtained by liposuction contains a large amount of blood and anesthetic tumescent fluid, and a fat cleaning fluid needs to be added to the processing tank for cleaning.

[0108] In one embodiment, the fat washing fluid includes any one or more of the following: physiological saline, Ringer's solution, sodium lactate Ringer's solution, acetate Ringer's solution, compound sodium acetate Ringer's solution, sodium bicarbonate Ringer's solution; optionally, the fat washing fluid is sodium lactate Ringer's solution.

[0109] In one embodiment, the fat extract and the fat washing solution are mixed in a ratio of 1:1.

[0110] In one embodiment, the weight of the fat extract is between 100g and 1200g. Optionally, the mixing, shaking, and stratification operations are performed in a sealed sterile container; optionally, the container is a cylindrical jar.

[0111] In one embodiment, sodium lactate Ringer's is a drug, which is a sterile aqueous solution of sodium lactate, sodium chloride, potassium chloride and calcium chloride. It is a body fluid, electrolyte and acid-base balance regulator. The sodium lactate (C3H5NaO3) content should be 93.0% to 107.0% of the labeled amount; the sodium chloride (NaCl), potassium chloride (KCl) and calcium chloride (CaCl2·2H2O) content should be 95.0% to 105.0% of the labeled amount.

[0112] S102: The fat extract and the fat cleaning solution are mixed and shaken, and then allowed to stand and separate to obtain fat and waste liquid;

[0113] In a specific embodiment, after washing and standing, the liquid is layered as follows: the lower layer is blood, anesthesia swelling fluid and LR (sodium lactate Ringer's solution), and the upper layer is the washed fat tissue.

[0114] S103: Discharge the waste liquid to obtain cleaned fat.

[0115] In one embodiment, the waste liquid is discharged by monitoring the pressure in the waste liquid discharge pipeline to determine whether the waste liquid is completely discharged. When the pressure becomes smaller, it is determined that all the waste liquid is discharged.

[0116] In one embodiment, during the waste liquid discharge process, the waste liquid discharge status and fat cleaning status are monitored by detecting the indicators of the waste liquid in the waste liquid discharge pipeline. When the waste liquid is discharged through the discharge pipeline, if the detected feedback voltage is greater than a preset voltage, it is determined that the waste liquid has not been completely discharged and enters the next cleaning; when the waste liquid is discharged through the discharge pipeline, if the detected feedback voltage is less than the preset voltage, it is determined that the waste liquid has been completely discharged and the fat cleaning is completed to obtain cleaned fat.

[0117] In one embodiment, the waste liquid is discharged n times, where n is a natural number greater than or equal to 1. During each discharge, the completion of the fat cleaning is monitored by detecting an indicator of the waste liquid in the waste liquid discharge pipeline. Furthermore, the feedback voltage of the waste liquid in the waste liquid discharge pipeline is compared with a preset voltage threshold to determine the fat cleaning status. When the feedback voltage is higher than the preset voltage threshold, fat cleaning fluid is injected and the next cleaning process is performed. When the feedback voltage is lower than the preset voltage threshold, the cleaning is determined to be complete, and the cleaned fat is obtained.

[0118] In a specific embodiment, fat cleaning monitoring: The feedback voltage corresponding to the clean cleaning liquid is fed back to the voltage feedback port VP2 (the more turbid the cleaning liquid, the greater the feedback voltage of the optical sensor). Debug the voltage of the VP6 monitoring port to make VP6 = V0.3OD. After the cleaning process is left standing and stratified, start draining the cleaning liquid in the lower layer of the fat cleaning container. During the drainage process, the optical monitoring module continuously monitors VP2 and VP6. If VP2 > VP6, it indicates that the cleaning liquid in the pipeline is still turbid at this time, and another cleaning is required. As the number of cleanings increases, the cleaning liquid in the pipeline becomes cleaner (the color change becomes lighter), and the feedback voltage VP2 of the optical sensor becomes smaller. Until VP2 < VP6, it indicates that the cleaning liquid in the pipeline is already clean at this time, and this cleaning is set as the last cleaning. Then, drain the remaining cleaning liquid in the treatment tank in excess to end the cleaning process.

[0119] The method further includes automatically unclogging. When a clogging occurs during the waste liquid drainage process, automatic unclogging is performed. Among them, when the clogging occurs, the pressure in the drainage pipeline becomes smaller, the waste liquid drainage stops, and the automatic unclogging program is waited to be executed. The automatic unclogging includes forward unclogging and / or reverse unclogging. The forward unclogging is carried out by obtaining the fat cleaning liquid to flush the clogging point. The reverse unclogging is carried out by flushing the clogging point with the waste liquid.

[0120] The forward unclogging is carried out by a high-intensity flushing speed, and the reverse unclogging is carried out by a low-intensity flushing speed. When the unclogging is forward unclogging, open the stop valve on the inlet pipeline path to form an inlet passage, and then start the power pump to provide pressure to press the fat cleaning liquid into the mesh filter for flushing to complete the unclogging. Optionally, the power pump started after forming the inlet passage provides pressure through high-speed forward operation.

[0121] Optionally, when the unclogging is reverse unclogging, open the stop valve on the drainage pipeline path to form a drainage passage, and then start the power pump to provide pressure to press the waste liquid back to flush the mesh filter to complete the unclogging. Optionally, the power pump opening the drainage pipeline path provides pressure through low-speed reverse operation. Optionally, the power pump runs for n seconds continuously, where n is a natural number greater than 1. Optionally, within s seconds after starting to drain the waste liquid, the pressure sensor detects the pressure in the pipeline. When the pressure becomes smaller, it indicates that the mesh filter is clogged, where s is a natural number greater than 1. Optionally, the change in pressure is detected within 5.5 s of draining the waste liquid.

[0122] Figure 5 is a schematic diagram of the fat automatic cleaning system provided by the embodiment of the present application, specifically including:

[0123] Acquisition module: Acquire fat extracts and fat cleaning liquid;

[0124] Cleaning module: The fat extract and fat cleaning solution are mixed and shaken, and then allowed to stand and separate to obtain fat and waste liquid;

[0125] Separation module: discharges the waste liquid to obtain cleaned fat.

[0126] FIG8 is a schematic diagram of a method for automatically obtaining fat matrix components according to an embodiment of the present application, comprising:

[0127] S101: Obtaining fat and fat decomposition liquid and mixing them to obtain a mixed liquid containing fat matrix components;

[0128] In one embodiment, the fat is mixed with the lipolysis liquid to obtain a mixed liquid, in which the lipolysis liquid decomposes the fat to obtain a mixed liquid containing fat matrix components, including fat tissue fragments and the lipolysis liquid.

[0129] In one embodiment, the fat is extracted from the human body and then washed; optionally, the weight of the fat is selected between 50g and 400g.

[0130] In one embodiment, the lipolysis solution is an enzyme solution for lipolysis; optionally, the enzyme solution comprises one or more of the following: Clostridium collagenase and neutral protease, trypsin, Clostridium enzyme and neutral protease lytic enzyme and thermolytic enzyme; optionally, the enzyme solution is celase enzyme reagent;

[0131] Optionally, the fat and the lipolysis liquid are mixed according to a ratio as shown in Table 2.

[0132] Table 2 Mixing ratio

[0133] S102: the mixed liquid containing the fat matrix component is allowed to stand for stratification, wherein the upper layer is waste liquid and the lower layer is liquid containing the fat matrix component;

[0134] In one embodiment, the mixed liquid containing the fat matrix component is layered to form a mixed waste liquid consisting of fat tissue fragments and lipolysis liquid in the upper layer, and a liquid containing the fat matrix component in the lower layer.

[0135] S103: extracting the liquid containing the fat matrix component to obtain the fat matrix component.

[0136] In one embodiment, the extraction includes M times, each time extracting N milliliters, where M is a natural number greater than or equal to 1 and N is a natural number less than 85. When the single extraction volume meets a preset threshold, the extraction is paused and the extracted fat matrix component is waited for to be delivered to a cache. When the delivery of the fat matrix component is completed, the next extraction is performed. When the single extraction volume does not meet the preset threshold but the extraction automatically ends, the extracted fat matrix component is delivered to the cache, and the extraction process ends to obtain the fat matrix component.

[0137] In one embodiment, the extraction further includes fat matrix component detection. Each time the extraction is performed, it is detected whether there is fat matrix component in the extraction pipeline. When the detection result is fat matrix component, the extraction is continued; when the detection result is waste liquid, the extraction is terminated.

[0138] Furthermore, the fat matrix component detection is to determine the type of liquid in the pipeline by monitoring the real-time voltage obtained by the extraction pipeline. When the real-time voltage is less than a preset voltage, it is determined to be a fat matrix component and extraction continues. When the real-time voltage is greater than the preset voltage, it is determined to be waste liquid and extraction ends.

[0139] Optionally, when the voltage value of the real-time voltage detection is less than 3.3 VDC, it is determined to be a fat matrix component.

[0140] In one embodiment, the fat washing solution includes one or more of the following: normal saline, Ringer's solution, sodium lactate Ringer's solution, acetate Ringer's solution, compound sodium acetate Ringer's solution, sodium bicarbonate Ringer's solution;

[0141] Optionally, the fat washing solution is sodium lactate Ringer's solution.

[0142] In one embodiment, the method further comprises pumping back the waste liquid. After the extraction of the fat matrix components is completed, waste liquid exists in the extraction pipeline, and the waste liquid is pumped back; optionally, the waste liquid is pumped back at a low speed.

[0143] In a specific embodiment, 360 g of fat and 5.0 ml of decomposition liquid are decomposed to obtain a liquid containing fat matrix components. Further, extraction is performed, and 83 ml is set to be extracted each time. During the first round of extraction, the voltage change in the pipeline is detected. If the voltage is less than 3.3 VDC, it is determined to be fat matrix components. After the first round of extraction, a second round of extraction is performed. Until the fourth round, during the extraction process, if the voltage is greater than or equal to 3.3 VDC, it is determined to be waste liquid, the extraction is terminated, the fat matrix components in the pipeline are transported to a buffer container, and the waste liquid is pumped back to its original location.

[0144] In one embodiment, the method further includes automatically washing the fat matrix components, washing the fat matrix components to obtain washed fat matrix components, and the washing is divided into two steps: enrichment and resuspension; the fat matrix components in the fat matrix component liquid are extracted by the enrichment, and the fat matrix components are washed by resuspension, and the enrichment and resuspension are performed in sequence, the enrichment is repeated k times, and the resuspension is repeated m times to obtain the washed fat matrix, where k and m are natural numbers greater than 1.

[0145] In one embodiment, the fat washing solution includes one or more of the following: physiological saline, Ringer's solution, sodium lactate Ringer's solution, acetate Ringer's solution, compound sodium acetate Ringer's solution, sodium bicarbonate Ringer's solution; optionally, the fat washing solution uses sodium lactate Ringer's solution.

[0146] In one embodiment, the enrichment and extraction separates the fat matrix component and waste liquid in the fat matrix component liquid by high-speed rotation, and the waste liquid is discharged through a pipeline to obtain the fat matrix component; optionally, the speed of the high-speed rotation is greater than 1500 revolutions per second.

[0147] In one embodiment, the resuspension comprises two parts: shaking and centrifugation, and the specific steps are:

[0148] Step 1: Get fat cleaning solution;

[0149] Step 2: The fat washing liquid is collected and enriched with the fat matrix components, and then shaken and washed to obtain a mixed liquid;

[0150] Step 3: separating the washed fat matrix component and the washing waste liquid in the mixed solution by centrifugation, and discharging the washing waste liquid through a pipeline to obtain the washed fat matrix component;

[0151] Optionally, the oscillation is performed by low-speed rotation for oscillation cleaning; optionally, the speed of the low-speed rotation is in the range of 0-300 rpm; optionally, the volume of the fat cleaning liquid obtained is in the range of 55-85 ml; optionally, the centrifugation is performed by high-speed rotation for separation.

[0152] In one embodiment, the method further includes cleaning of the transplanted fat, and the cleaning of the transplanted fat is performed in parallel with the automatic cleaning of the fat matrix component to obtain cleaned transplanted fat and cleaned fat matrix component respectively; optionally, the step of cleaning the transplanted fat is: obtaining transplanted fat and fat cleaning liquid, mixing the fat cleaning liquid with the transplanted fat by oscillating, and cleaning to obtain cleaned transplanted fat and fat cleaning waste liquid, and discharging the fat cleaning waste liquid to obtain the cleaned transplanted fat.

[0153] The disclosed embodiments of the present application also provide a computer program product or system, including a computer program, which, when executed by a processor, implements the above-mentioned method for detecting the sealing of the pipeline after installation, or implements the above-mentioned method for automatic fat cleaning, or implements the above-mentioned method steps for automatically obtaining fat matrix components.

[0154] FIG9 is a schematic diagram of a system for automatically obtaining fat matrix components provided in an embodiment of the present application, specifically comprising:

[0155] Acquisition module: Acquisition of fat and fat decomposition solution and mixing thereof to obtain a mixed solution containing fat matrix components;

[0156] Standing module: the mixed liquid containing the fat matrix component is stood to separate into layers, the upper layer is waste liquid, and the lower layer is liquid containing the fat matrix component;

[0157] Extraction module: extracts the liquid containing the fat matrix component to obtain the fat matrix component.

[0158] The disclosed embodiment of the present application also provides a computer device, comprising: a memory and a processor; the memory is used to store program instructions; the processor is used to call the program instructions, and when the program instructions are executed, any one of the above-mentioned methods for detecting the sealing of the pipeline after installation, or the above-mentioned method for automatically cleaning fat, or the above-mentioned method for automatically obtaining fat matrix components is executed.

[0159] The disclosed embodiments of the present application also provide a computer-readable storage medium storing a computer program. When the computer program is executed by a processor, it performs any one of the above-mentioned methods for detecting the sealing of pipelines after installation, or performs the above-mentioned method for automatically cleaning fat, or performs the above-mentioned method for automatically obtaining fat matrix components.

[0160] The present application provides an apparatus for fat cleaning, fat matrix acquisition and cleaning, and a pipeline sealing test after installation, including:

[0161] A pipeline to be tested, wherein the pipeline to be tested is composed of M connected pipeline paths, where M is a natural number greater than 1;

[0162] A pump, passing through the pipeline to be tested, for providing power;

[0163] The pressure detection module includes L pressure sensors, where L is a natural number greater than or equal to 2. The pipeline passes through the pressure detection module, wherein the pipeline passes through a first pipeline pressure sensor, a pump, and a second pipeline pressure sensor in sequence. The gas in the pipeline flows as the pump rotates. The pressure sensor detects the change in pipeline pressure to determine the sealing of the pipeline, including: when the pump rotates forward, the first pipeline pressure sensor detects that the pressure in the pipeline decreases and the second pipeline pressure sensor detects that the pipeline pressure increases, and the pipeline is determined to be in a sealed state; or when the pump rotates reversely, the first pipeline pressure sensor detects that the pressure in the pipeline increases and the second pipeline pressure sensor detects that the pressure in the pipeline decreases, and the pipeline is determined to be in a sealed state; the pressure detection module also includes blockage detection; the blockage detection is that after the test liquid flows through the pipeline, the first pipeline pressure sensor detects the pressure of the pipeline liquid inlet port, and the second pipeline pressure sensor detects the pressure of the pipeline liquid outlet port. When the pressure of the pipeline outlet port increases or the pressure of the pipeline inlet port decreases, the pipeline is determined to be blocked; when the pressure remains unchanged, the pipeline is determined to be in a normal state;

[0164] The photoelectric monitoring module includes an optical sensor, a voltage feedback port, a monitoring port, and a comparator. The photoelectric monitoring module is used to detect whether the pipeline is correctly installed. The pipeline passes through the photoelectric monitoring module. The optical sensor performs pipeline detection to obtain a feedback voltage, and the feedback voltage is fed back to the voltage feedback port. The comparator then compares the feedback voltage value of the voltage feedback port with the preset threshold value of the monitoring port. When the feedback voltage is greater than the preset threshold value, it is determined that the pipeline is correctly installed. Otherwise, it is unsuccessful, and a prompt sound and prompt message are used to remind the user to reinstall it.

[0165] In one embodiment, when the airflow or liquid flows in the pipeline, it passes through the pipeline second pressure sensor, the pump, and the pipeline first pressure sensor in sequence; when the airflow or liquid flows in the pipeline in the reverse direction, it passes through the pipeline first pressure sensor, the pump, and the pipeline second pressure sensor in sequence.

[0166] In one embodiment, the forward rotation causes the airflow or liquid in the pipeline to flow from the liquid inlet port to the liquid outlet port; the reverse rotation causes the airflow or liquid in the pipeline to flow from the liquid outlet port to the liquid inlet port.

[0167] In one embodiment, the pipeline to be tested is divided into a liquid inlet pipeline and a liquid discharge pipeline, and the material is input through the liquid inlet pipeline and discharged through the liquid discharge pipeline. In a specific embodiment, the installation of the device is shown in Figure 2, including pipelines: transporting various liquids.

[0168] Peristaltic pump: can drive liquid / substance to flow in the pipeline, with three speed modes.

[0169] Pressure sensor: There are two pressure sensors P1 and P2, which can monitor the pressure changes in the pipeline.

[0170] Optical monitoring module: consists of a real-time voltage feedback port: VP2 and three monitoring ports (adjustable): VP9, ​​VP6 and VP3, an optical sensor, and three comparators (analog-to-digital converters).

[0171] VP2: The feedback voltage of the optical sensor is output to VP2;

[0172] VP9: Monitoring port, used to monitor whether the pipeline is correctly installed into the optical sensor when installing consumables.

[0173] VP6: Monitoring port, used to monitor whether the waste liquid is clean during the waste liquid discharge process of the fat washing process.

[0174] VP3: Monitoring port for detecting ruptured fat tissue.

[0175] Optical sensor: The optical sensor emits an 890nm light source into the pipeline. Different substances flowing through the pipeline will cause the optical sensor to feedback different voltages.

[0176] Comparator: Compares the voltage value of the real-time feedback port with the voltage value of the monitoring port and outputs a digital signal of 0 or 1.

[0177] In a specific embodiment, a blockage test is performed after a sealing test is performed on the pipeline. The pipeline also includes N stop valves for controlling the flow of materials in the pipeline, where N is a natural number greater than or equal to 1; the positions of P1 and P2 are shown in Figure 2, and the pipeline passes through the peristaltic pump and is distributed on both sides of the peristaltic pump. The pipeline through which P1 passes is connected to one side of the pipeline passing through the peristaltic pump, and is connected to the pipeline passing through the fourth stop valve to form a three-way intersection No. 4; the pipeline through which P2 passes is connected to the other side of the pipeline passing through the peristaltic pump, and is connected to the pipeline passing through the first stop valve to form a three-way intersection No. 1; wherein the rotation of the peristaltic pump provides power for material transportation.

[0178] In a specific embodiment, the pipeline passing through the peristaltic pump and connected to P1 also includes a fifth stop valve on one side. The pipeline passing through the fifth stop valve is connected to the pipeline passing through the peristaltic pump to form a three-way fork No. 5. The pipeline passing through the peristaltic pump first passes through the three-way fork No. 5 and then passes through the three-way fork No. 4.

[0179] The pipeline to be tested includes a liquid inlet pipeline and a liquid discharge pipeline. The device also includes a fat cleaning container. The liquid inlet pipeline and the liquid discharge pipeline are connected to the fat cleaning container. The path for transporting liquid in the pipeline to be tested also includes a stop valve. The liquid inlet pipeline includes a first stop valve and a fifth stop valve, and the path of the liquid discharge pipeline includes a second stop valve and a fourth stop valve. The pump is located between the first stop valve and the fifth stop valve of the liquid inlet pipeline, and the pipeline through which the fat cleaning liquid passes passes through the first stop valve, the pump, and the fifth stop valve in sequence; the power pump is located between the second stop valve and the fourth stop valve of the liquid discharge pipeline; the pipeline through which the waste liquid passes passes through the second stop valve, the pump, and the fourth stop valve in sequence; the liquid discharge pipeline passes through the photoelectric monitoring module, and the liquid discharge pipeline through which the waste liquid passes passes through the photoelectric control module, the second stop valve, the pump, and the fourth stop valve in sequence;

[0180] After the photoelectric monitoring module detects that the pipeline is correctly installed and the pressure sensor determines that the pipeline is in a sealed state, the fat is injected into the fat cleaning container and the fat cleaning liquid is input through the liquid inlet pipeline. The fat cleaning container is vibrated and shaken to clean the fat to obtain the cleaned fat and cleaning waste liquid. The cleaning waste liquid is discharged through the drainage pipeline and the waste liquid feedback voltage when the waste liquid flows through the drainage pipeline is detected by the photoelectric monitoring module to determine whether the fat is cleaned; wherein, the waste liquid feedback voltage of the voltage feedback port is compared with the waste liquid monitoring threshold of the monitoring port by a comparator. When the waste liquid feedback voltage is greater than the waste liquid monitoring threshold, it is determined that the fat is not cleaned, and the fat cleaning liquid is input through the pipeline to continue the next cleaning. Otherwise, it is determined that the fat is cleaned and the current cleaning is the final cleaning.

[0181] The device also includes a device for unblocking blockages. During the waste liquid discharge process, the first pressure sensor of the pipeline detects that the pressure of the discharge pipeline has decreased and the pump stops providing pressure to discharge the waste liquid. The device enters the steps of forward unblocking and / or reverse unblocking; when the unblocking is forward unblocking, the stop valve on the liquid inlet pipeline is opened to form a liquid inlet passage, and then the pump is started to provide pressure to pressurize the fat cleaning liquid to flush the mesh filter to complete the unblocking; when the unblocking is reverse unblocking, the pump is started to provide pressure to pressurize the waste liquid back to reversely flush the mesh filter to complete the unblocking.

[0182] The pipeline also includes a liquid extraction pipeline, through which fat matrix components are output. When the device extracts fat matrix, the photoelectric control module is located in the liquid extraction pipeline path. The fat matrix passes through the photoelectric control module, the second stop valve, the pump, and the sixth stop valve in the liquid extraction pipeline in sequence. The comparator compares the real-time voltage with the preset voltage to determine the type of liquid in the pipeline. When the feedback voltage is lower than the preset voltage threshold, it is determined to be fat matrix components. When the feedback voltage is higher than the preset voltage threshold, it is determined to be waste liquid.

[0183] The device also includes a buffer container and a waste liquid container, wherein the extracted fat matrix component is stored in the buffer container, and the discharged waste liquid is stored in the waste liquid container; the buffer container is a centrifugal chamber, including a static module, and the static module is composed of a liquid inlet, a liquid outlet, and an in-chamber delivery pipeline. The fat matrix component liquid enters the centrifugal chamber through the liquid inlet and enters the interior of the centrifugal chamber along the in-chamber delivery pipeline;

[0184] The centrifugal chamber also includes a rotating module, which consists of a rotating central axis, a centrifugal cavity, and a storage area; N centrifugal cavities are connected with the rotating central axis as the center, and the two ends of the N centrifugal cavities are respectively connected to a storage area, where N is a natural number greater than or equal to 1; wherein the centrifugal cavity is connected to the storage area at an inclined angle; the delivery pipeline of the static module is connected to the N centrifugal cavities, and the fat matrix component liquid is delivered to the centrifugal cavity through the delivery pipeline of the static module, and the fat matrix component liquid is cleaned by rotating the centrifugal cavity in the rotating module; the pipeline also includes a liquid outlet pipeline, which is connected to the liquid outlet, and the waste liquid in the cabin is discharged through the liquid outlet pipeline. The waste liquid in the cabin passes through the third stop valve, the pump, and the fourth stop valve in sequence through the liquid outlet pipeline to the waste liquid container.

[0185] The cleaning process includes enrichment, wherein the enrichment yields separated fat matrix components and chamber waste liquid, which are then transported to a liquid outlet via a delivery pipeline and then discharged through the liquid outlet pipeline to yield the fat matrix components. The cleaning process also includes resuspending the fat matrix components, which comprises first delivering a fat cleaning solution into the centrifugal chamber via a liquid inlet and chamber delivery pipeline, oscillating and cleaning the fat matrix components to yield cleaned fat matrix components and cleaning waste liquid, then centrifuging the fat matrix components to collect them in a storage area connected to the centrifugal chamber to yield the cleaned fat matrix components, and discharging the cleaning waste liquid through the liquid outlet and the liquid outlet pipeline.

[0186] In one embodiment, the fat extract and fat cleaning solution are mixed, shaken, and allowed to stand in a processing tank (fat cleaning container); the processing tank is a closed cylindrical tank body, one end of which includes a first liquid inlet, and the other end of which includes a liquid outlet and a second liquid inlet. The curved surface of the tank body includes large and small grooves, which are used to fit the tank body onto the bracket in a semi-suspended state and then automatically shaken. Furthermore, the large and small grooves correspond to the upper and lower positions of the bracket.

[0187] In one embodiment, the fat extract is injected through the first liquid inlet, and the liquid inlet is closed after the injection; the fat cleaning solution is injected through the second liquid inlet, and the liquid inlet is closed after the injection.

[0188] In one embodiment, a filter screen is contained in the processing tank. The filter screen is located at the liquid discharge port to prevent fat from being discharged. Further, the diameter of the mesh holes of the filter screen is smaller than the diameter of fat. The fat cleaning liquid is input through the liquid inlet pipeline and enters the processing tank through the second liquid inlet. The waste liquid is discharged through the liquid discharge port into the waste liquid storage container (waste liquid container) through the liquid discharge pipeline; the waste liquid storage container is connected to the pipeline for storing the waste liquid.

[0189] In one embodiment, for fat cleaning, when the photoelectric control module is located in the path of the liquid discharge pipeline, the voltage change in the pipeline is monitored through the photoelectric control module. Specifically, the real-time voltage of the liquid in the pipeline is fed back through the real-time voltage feedback port, and the preset voltage is fed back through the monitoring port. The fixed voltage is set as the preset voltage, and the preset voltage is set as 1.75 VDC. The comparator compares the magnitudes of the real-time voltage and the preset voltage to determine the completion of fat cleaning. When the feedback voltage is higher than the preset voltage threshold, the fat cleaning continues. When the feedback voltage is lower than the preset voltage threshold, it is determined that the cleaning is completed.

[0190] In one embodiment, the first pipeline pressure sensor is located in the path of the liquid discharge pipeline. The pressure in the liquid discharge pipeline is detected through the first pipeline pressure sensor to determine whether the liquid discharge management is blocked. When the pressure becomes smaller, it is determined that there is a blockage.

[0191] One end of the liquid discharge path where the first pipeline pressure sensor is located intersects the middle liquid discharge path between the second stop valve and the power pump, and the other end is closed.

[0192] In a specific embodiment, 1. Regarding the optical density corresponding to clean waste liquid is 0.3 (the more turbid the waste liquid, the greater the optical density and the greater the feedback voltage of the optical sensor).

[0193] 2. Insert an optical density sheet calibrated to 0.3 into the optical sensor, measure the feedback voltage V0.3OD of the optical sensor, and then adjust the voltage of the VP6 monitoring port to make VP6 = V0.3OD.

[0194] 3. After standing and stratifying during the cleaning process, start to discharge the waste liquid at the lower layer of the processing tank. During the liquid discharge process, the optical monitoring module continuously monitors VP2 and VP6. If VP2 > VP6, it indicates that the waste liquid in the pipeline is still turbid at this time, and the next cleaning needs to continue.

[0195] 4. As the number of cleaning times increases, the waste liquid in the pipeline becomes cleaner and cleaner (the color change will fade), and the feedback voltage VP2 of the optical sensor will become smaller and smaller. Until VP2 < VP6, it indicates that the liquid in the pipeline is already clean at this time, and this cleaning is set as the last cleaning, and then the remaining waste liquid in the processing tank is discharged excessively to end the cleaning process.

[0196] In a specific embodiment, if VP2 < VP6, the central processing unit will receive a "0" signal, indicating that the waste liquid in the lower layer has been basically drained; if VP2 > VP6, the central processing unit will receive a "1" signal, indicating that the waste liquid in the lower layer is still turbid. The principle is shown in Figure 6. In a specific embodiment, during the liquid drainage process shown in Figure 7, the voltage response of the optical sensor changes. When the waste liquid with a darker color passes through the optical sensor (corresponding to around 1-265 in Figure 7), the device continues to drain the liquid. When the waste liquid with a lighter color passes through the optical sensor, the response voltage of the optical sensor drops until it drops below the monitoring threshold. At this time, the system considers the waste liquid in the treatment tank to be clean, and then the system drains the remaining waste liquid. Finally, only the washed adipose tissue remains in the treatment tank.

[0197] In a specific embodiment, after repeated debugging and verification, the response voltage value of the clean waste liquid passing through the optical sensor is selected to be around 1.75 VDC. Therefore, setting the monitoring threshold of the anesthetic swelling mixture to 1.75 VDC can effectively judge the cleanliness of the waste liquid in the lower layer of the remaining fat in the treatment tank.

[0198] In one embodiment, for the blockage dredging during fat cleaning, the power pump provides power, and the power pump runs for n seconds continuously, where n is a natural number greater than 1.

[0199] In one embodiment, within s seconds from the start of draining the waste liquid, the first pressure sensor in the pipeline detects the pressure in the pipeline. When the pressure decreases, it indicates that the mesh filter is blocked, and s is a natural number greater than 1.

[0200] In one embodiment, the change in pressure is detected within 5.5 s of draining the waste liquid.

[0201] In a specific embodiment, 1. Because there is a mesh filter in the structure of the treatment tank, it can allow the passage of liquid and block adipose tissue.

[0202] 2. During the fat cleaning process, it is possible that the adipose tissue blocks the filter. Therefore, during the drainage of the waste liquid, the pressure sensor P2 continuously monitors the pressure in the pipeline at the waste liquid discharge outlet of the treatment tank.

[0203] 3. If within 5.5 seconds after the start of liquid drainage, the pressure sensor P2 detects a vacuum condition (decrease in pressure) in the pipeline, it indicates that the filter is blocked.

[0204] 4. If a blockage occurs, the system will execute the filter dredging program:

[0205] 4.1 Open stop valves 1 and 5 (the first stop valve and the fifth stop valve), start the pump at high speed and forward direction, and continue working for 5 seconds. (Sodium lactate Ringer's solution is used to flush the filter here);

[0206] 4.2 Open stop valves 2 and 4 (the second stop valve and the fourth stop valve), start the pump to run in reverse at low speed, and continue working for 15 seconds. (Here is to dredge the filter in reverse through the waste liquid discharge path);

[0207] 5. After completing the filter unclogging procedure, drain the liquid.

[0208] In one embodiment, within s seconds after the waste liquid is discharged, the pressure sensor detects the pressure in the pipeline. When the pressure decreases, it indicates that the mesh filter is clogged, and s is a natural number greater than 1.

[0209] In one embodiment, the pressure change is detected within 5.5 seconds of draining the waste liquid.

[0210] In a specific embodiment, 1. Because there is a mesh filter in the structure of the processing tank, it can achieve the passage of liquid and the isolation of fat tissue.

[0211] 2. During the fat cleaning process, the filter may be blocked by fat tissue. Therefore, when discharging waste liquid, the pressure sensor P2 will continuously monitor the pressure in the pipeline at the waste liquid outlet of the treatment tank.

[0212] 3. If the pressure sensor P2 detects a vacuum in the pipeline (pressure decreases) within 5.5 seconds after the start of drainage, it means that the filter is clogged.

[0213] 4. If blockage occurs, the system will perform the filter unclogging procedure:

[0214] 4.1 Open stop valves 1 and 5, start the pump in high-speed forward direction, and continue working for 5 seconds. (Sodium lactate Ringer's solution is used to flush the filter);

[0215] 4.2 Open stop valves 2 and 4, start the pump to run in reverse at low speed, and continue working for 15 seconds. (This is to dredge the filter in reverse through the waste liquid discharge path);

[0216] 5. After completing the filter unclogging procedure, drain the liquid.

[0217] In one embodiment, fat is washed to obtain cleaned fat, and fat matrix extraction is performed on the cleaned fat. The cleaned fat is then cracked in a processing tank (a fat washing container or a storage container) to obtain a mixed liquid containing fat matrix components. The fat matrix components are output through the liquid extraction pipeline path, and waste liquid is discharged through the liquid discharge pipeline path. The fat matrix components pass through the second stop valve and the sixth stop valve in the liquid extraction pipeline path.

[0218] When the photoelectric control module is located in the liquid extraction pipeline, the photoelectric control module monitors the extraction of the fat matrix component, and the fat matrix component passes through the photoelectric control module, the second stop valve, and the sixth stop valve on the liquid extraction pipeline in sequence; the comparator compares the voltage value of the real-time voltage feedback port with the preset voltage value of the monitoring port, and obtains the symbol representing the type of liquid in the pipeline through digital-to-analog conversion; when the feedback voltage is lower than the preset voltage threshold, it is determined to be fat matrix component, and when the feedback voltage is higher than the preset voltage threshold, it is determined to be waste liquid; the preset voltage is set to a voltage value less than or equal to 3.3VDC.

[0219] Optionally, when the liquid is determined to be waste liquid, the sixth stop valve is closed, and then the power pump is turned on to provide pressure to push the waste liquid back into the treatment tank; the power pump provides power by reversing;

[0220] Optionally, the power pump stops running after continuously rotating in reverse at a low speed for n seconds, where n is a natural number greater than 1;

[0221] Optionally, the power pump stops running after continuously rotating at a low speed for 7 seconds.

[0222] Optionally, the power pump is located between the second stop valve and the fourth stop valve in the drainage pipeline path, the drainage pipeline path is connected to the extraction pipeline path to form a pumping and drainage bifurcation, the pumping and drainage bifurcation is located between the fourth stop valve and the power pump in the drainage pipeline path, and at the same time, the pumping and drainage bifurcation is located between the second stop valve and the sixth stop valve in the extraction pipeline path; the device also includes a cache container (centrifuge chamber) and a waste liquid container, the cache container is used to store the extracted fat matrix components, and the waste liquid is stored in the waste liquid container.

[0223] In a specific embodiment, fat is obtained, the fat is cracked, and after standing, the upper layer in the processing tank (storage container) is the ruptured fat tissue after cracking (hereinafter referred to as waste liquid), and its corresponding voltage is much greater than 3.3, and the lower layer is a liquid containing fat matrix components, and its corresponding real-time voltage is much less than 3.3.

[0224] In a specific embodiment, 1. Debug the voltage of the VP3 monitoring port to make VP3 = 3.3V.

[0225] 2. After the fat is cracked and left standing, the liquid containing the fat matrix component at the lower layer of the treatment tank starts to be transferred into the centrifugation chamber (buffer container). During the transfer process, the optical monitoring module continuously monitors VP2 and VP3. If VP2 < VP3, it means that the liquid in the treatment tank still contains the fat matrix component at this time, and the next transfer is required.

[0226] 3. As the number of transfers increases, the liquid containing the fat matrix component at the lower layer becomes less and less. Until the waste liquid enters the pipeline, at this time, the optical monitoring module will detect that VP2 > VP3, which means that all the liquid containing the fat matrix component at the lower layer in the treatment tank has been transferred completely, and the system stops the transfer. The transfer process is shown in Figure 10.

[0227] After the system stops the transfer, 1. There will be waste liquid in the pipeline between the treatment tank and the centrifugation chamber (buffer container).

[0228] 2. At this time, the system will execute the waste liquid pumping-back program:

[0229] 2.1 Open the stop valves (valves) 2 and 6, start the pump to run in reverse at a low speed (100 ml / min), and keep working for 7 seconds.

[0230] 3. The volume of the pipeline between the treatment tank and the centrifugation chamber is about 9 ml, and the reverse operation for 7 seconds can discharge about 12 ml of liquid. Therefore, this fat pumping-back program can completely discharge the waste liquid in the pipeline between the treatment tank and the centrifugation chamber.

[0231] This program can effectively prevent the cleaning liquid from bringing the residual waste liquid in the pipeline into the centrifugation chamber to pollute the fat matrix component during the subsequent cleaning of the fat matrix component.

[0232] In a specific embodiment, after the fat is cracked and left standing in the treatment tank for a period of time, the liquid stratification in the treatment tank is as follows: the lower layer is the fat matrix component, and the upper layer is the broken fat tissue (waste liquid). At this time, the fat matrix component needs to be transferred to the buffer container.

[0233] During the transfer of the fat matrix component into the buffer container, after detecting the broken fat tissue, the pump reverses to pump back some of the broken fat tissue in the pipeline into the treatment tank. The type of liquid conveyed in the pipeline is identified by detecting the voltage change. The voltage response change of the optical sensor during the transfer of the fat matrix component into the buffer container is shown in Figure 11.

[0234] When the mixture of the adipose stromal component and the ruptured adipose tissue just passes through the optical sensor (corresponding to about 307 times in the figure, 1.072 VDC), the liquid distribution in the pipeline is as follows: from the processing tank to the optical sensor, it is a mixture of the adipose stromal component and grease, and from the optical sensor to the buffer container, it is the adipose stromal component.

[0235] If the monitoring threshold value of the ruptured adipose tissue (VP3) is set too low, it will cause the adipose stromal component between the optical sensor and the buffer container to be pumped back to the processing tank instead of being transferred to the buffer container, resulting in a waste of excessive adipose stromal components.

[0236] If the monitoring threshold value of the ruptured adipose tissue (VP3) is set too high, it will cause too much ruptured adipose tissue to enter the buffer container, resulting in impure adipose stromal components obtained. After repeated debugging and verification, it is more reasonable to set the monitoring threshold value of the ruptured adipose tissue (VP3) to 3.3 VDC. That is, it can ensure that not too much adipose stromal components are wasted and can limit the ruptured adipose tissue from entering the centrifugation chamber.

[0237] In a specific embodiment, the comparator in the optoelectronic control module compares the voltage value of the real-time feedback port with the voltage value of the monitoring port and inputs it to the processor for processing. If VP2 < VP3, the processor will receive the signal "COLOR1 = 0", that is, no ruptured adipose tissue is detected;

[0238] If VP2 > VP3, the processor will receive the signal "COLOR1 = 1", that is, ruptured adipose tissue is detected. The regulation parameters of the optoelectronic control module are shown in Table 3.

[0239] Table 3 Regulation Parameters

[0240] In an embodiment, during the enrichment process, the centrifugation chamber realizes material separation through high-speed rotation; the speed of the high-speed rotation is greater than 1500 revolutions per second.

[0241] In an embodiment, continuously inputting the adipose stromal component liquid L times corresponds to performing L times of the above-mentioned enrichment, and L is a natural number greater than 1.

[0242] In an embodiment, the oscillation cleaning during resuspension is low-speed rotation, and the speed is within the range of 0 - 300 revolutions per second; optionally, the centrifugation is high-speed rotation, and the speed is greater than 1500 revolutions per second; optionally, the resuspension is performed H times, and H is a natural number greater than 1.

[0243] In one embodiment, the transplanted fat is injected into the cleaning container (fat cleaning container) through the injection port (first liquid inlet), and the fat cleaning liquid is delivered to the cleaning container through the second liquid inlet. The cleaning container is then shaken to obtain cleaned transplanted fat and transplanted fat cleaning waste liquid. The transplanted fat cleaning waste liquid is discharged through a waste discharge line connected to the liquid outlet to obtain cleaned transplanted fat. Alternatively, the cleaned fat matrix component is injected into the cleaning container and mixed with the cleaned transplanted fat, and then extracted using a syringe for disease treatment.

[0244] In one embodiment, when the fat matrix components in the device are resuspended, fat cleaning liquid is input through the liquid inlet pipeline, and the liquid inlet pipeline is connected to the liquid extraction pipeline path to form a suction bifurcation, and the suction bifurcation is located between the second shut-off valve and the power pump in the liquid extraction pipeline path. The fat cleaning liquid enters the liquid extraction pipeline path from the liquid inlet pipeline and is transported to the centrifugal chamber. The fat cleaning liquid is mixed with the fat matrix components to obtain a mixed solution, and then the mixed solution is washed by a low-speed oscillation centrifugal chamber. Finally, the mixed solution is centrifuged by a high-speed rotation centrifugal chamber to obtain washed fat matrix components and washing waste liquid, wherein the washing waste liquid is discharged to the waste liquid container through the liquid outlet pipeline, and the washed fat matrix is ​​stored in the storage area after centrifugation.

[0245] In one embodiment, during the fat matrix cleaning process, the transplanted fat is cleaned in parallel. The fat to be transplanted is injected into a storage container, and a fat cleaning solution is simultaneously introduced through the liquid inlet pipeline. After shaking and oscillating, the cleaned transplanted fat and transplanted fat cleaning waste liquid are obtained. The sixth shut-off valve is closed, and the transplanted fat cleaning waste liquid is discharged into the waste liquid container through the drainage pipeline path to obtain the cleaned transplanted fat. Optionally, the liquid inlet pipeline passes through the suction bifurcation, the extraction pipeline path, and the extraction and discharge bifurcation, and then branches into a rear-end liquid inlet pipeline. The extraction and discharge bifurcation forms a three-way junction. The rear-end liquid inlet pipeline is connected to the liquid inlet of the storage container. Optionally, the discharge of the transplanted fat cleaning waste liquid also includes manual discharge.

[0246] Optionally, after the transplanted fat is cleaned, cleaned transplanted fat and transplanted fat cleaning waste liquid are obtained, the transplanted fat cleaning waste liquid is discharged, and the cleaned fat matrix is ​​injected into a storage container, the cleaned fat matrix is ​​mixed with the cleaned transplanted fat, and they are extracted through a syringe for disease treatment.

[0247] In order to avoid ambiguity, this application makes a unified description of the stop valve in the priority application document. Based on the description of the stop valve in the priority application patent CN202410584697.5, the first stop valve, second stop valve, third stop valve, and fourth stop valve in the priority patent CN202410374922.2 are changed to the first stop valve, the fifth stop valve, the second stop valve, and the fourth stop valve;

[0248] Change the first valve, second valve, and third valve in the priority patent CN202410374921.8 to the second stop valve, fourth stop valve, and sixth stop valve;

[0249] In addition, for the same but different names, additional explanations are given in brackets at the end, for example, fat cleaning container, processing tank, and cleaning container mean the same thing; the photoelectric detection module is uniformly changed to photoelectric control module.

[0250] The validation results of this validation example demonstrate that assigning inherent weights to indications can improve the performance of the present method compared to the default settings. Those skilled in the art will readily appreciate that, for ease of description and brevity, the specific operating processes of the systems, devices, and units described above can be referenced to the corresponding processes in the aforementioned method embodiments and will not be further elaborated upon here. It should be understood that the disclosed systems, devices, and methods can be implemented in other ways within the several embodiments provided herein. For example, the device embodiments described above are merely illustrative. For example, the division of units described is merely a logical functional division. In actual implementation, other divisions may be employed, such as combining or integrating multiple units or components into another system, or omitting or disabling certain features. Furthermore, the coupling, direct coupling, or communication connection shown or discussed may be through interfaces, indirect coupling, or communication connection between devices or units, and may be electrical, mechanical, or other forms. The units described as separate components may or may not be physically separate, and the components shown as units may or may not be physical units, i.e., they may be located in one location or distributed across multiple network units. Some or all of the units may be selected to achieve the objectives of the present embodiment as needed. In addition, the functional units in the various embodiments of the present application may be integrated into one processing unit, or each unit may exist physically separately, or two or more units may be integrated into one unit. The above-mentioned integrated units may be implemented in the form of hardware or in the form of software functional units. Those skilled in the art will understand that all or part of the steps in the various methods of the above-mentioned embodiments may be completed by instructing the relevant hardware through a program, and the program may be stored in a computer-readable storage medium, which may include: a read-only memory (ROM), a random access memory (RAM), a disk or an optical disk, etc.

Claims

1. A method for detecting the sealing performance of a pipeline after installation, wherein the pipeline is installed in medical equipment, and the medical equipment includes a first pipeline pressure sensor, a pump, and a second pipeline pressure sensor, wherein: Methods for determining pipeline tightness by detecting pipeline pressure changes through pressure sensors include: When the pump rotates forward, the first pressure sensor of the pipeline detects that the pressure in the pipeline decreases or the second pressure sensor of the pipeline detects that the pressure in the pipeline increases, and the pipeline is determined to be in a sealed state; or when the pump rotates reversely, the first pressure sensor of the pipeline detects that the pressure in the pipeline increases or the pressure of the second pressure sensor of the pipeline decreases, and the pipeline is determined to be in a sealed state.

2. The method for detecting the sealing performance of a pipeline after installation according to claim 1, wherein: The method also includes blockage detection; the blockage detection is that after the test liquid flows through the pipeline, the first pressure sensor of the pipeline detects the pressure of the pipeline liquid inlet port, and the second pressure sensor of the pipeline detects the pressure of the pipeline liquid outlet port. When the pressure of the pipeline liquid outlet port increases or the pressure of the pipeline liquid inlet port decreases, it is determined that the pipeline is blocked; when the pressure remains unchanged, it is determined that the pipeline is in a normal state.

3. The method for detecting the sealing performance of pipelines after installation according to claim 1, wherein: The medical equipment also includes a photoelectric monitoring module, which consists of an optical sensor, a voltage feedback port, a monitoring port, and a comparator. The pipeline passes through the photoelectric monitoring module, and the photoelectric monitoring module detects whether the pipeline is correctly installed. The optical sensor performs pipeline detection to obtain a feedback voltage, and the feedback voltage is fed back to the voltage feedback port. The comparator then compares the feedback voltage value of the voltage feedback port with the preset threshold of the monitoring port. When the feedback voltage is greater than the preset threshold, it is determined that the pipeline is correctly installed. Otherwise, it is unsuccessful, and a prompt sound and prompt message are used to remind the user to reinstall it.

4. A method for automatic fat cleaning, wherein: The method for performing the method for detecting the sealing performance of a pipeline after installation according to any one of claims 1 to 3 to obtain a successfully installed and sealed pipeline comprises: Obtain fat aspirates and fat washes; The fat extract and the fat washing solution are mixed and shaken, and then allowed to stand and separate to obtain fat and waste liquid; The waste liquid is discharged to obtain the washed fat.

5. The method for automatic fat cleaning according to claim 4, wherein: The waste liquid discharge is determined by monitoring the pressure in the waste liquid discharge pipeline to determine whether the waste liquid is completely discharged. When the pressure becomes smaller, it is determined that all the waste liquid is discharged.

6. The method for automatic fat cleaning according to claim 5, wherein: The waste liquid is discharged n times, where n is a natural number greater than or equal to 1. During each discharge process, the completion of the fat cleaning is monitored by detecting the indicators of the waste liquid in the waste liquid discharge pipeline. The feedback voltage of the waste liquid in the waste liquid discharge pipeline is compared with a preset voltage threshold to determine the fat cleaning status. When the feedback voltage is higher than the preset voltage threshold, fat cleaning liquid is injected and the next cleaning is performed; when the feedback voltage is lower than the preset voltage threshold, it is determined that the cleaning is completed, and the cleaned fat is obtained.

7. The method for automatic fat cleaning according to claim 4, wherein: The method also includes automatic unblocking of blockages, and when blockage occurs during the waste liquid discharge process, automatic unblocking is performed; wherein, when the blockage occurs, the pressure of the discharge pipeline decreases, the discharge of the waste liquid is stopped, and the automatic unblocking procedure is waited for to be executed.

8. The method for automatic fat cleaning according to claim 7, wherein: The automatic dredging includes forward dredging and / or reverse dredging; the forward dredging is performed by flushing the blockage with fat cleaning fluid; the reverse dredging is performed by flushing the blockage with waste fluid.

9. The method for automatic fat cleaning according to claim 8, wherein: The forward dredging is performed by a high-intensity flushing speed, and the reverse dredging is performed by a low-intensity flushing speed.

10. A method for automatically obtaining fat matrix components, wherein: The method comprises: Obtain fat and fat decomposition liquid and mix them to obtain a mixed liquid containing fat matrix components; the fat is the fat cleaned by the automatic fat cleaning method according to claims 4-9; The mixed liquid containing the fat matrix component is allowed to stand for stratification, wherein the upper layer is waste liquid and the lower layer is liquid containing the fat matrix component; The liquid containing the fat matrix component is extracted to obtain the fat matrix component.

11. The method for automatically obtaining fat matrix components according to claim 10, wherein: The extraction includes M times, each time extracting N milliliters, where M is a natural number greater than or equal to 1 and N is a natural number less than 85. When the single extraction volume meets a preset threshold, the extraction is paused and the extracted fat matrix components are waited for to be delivered to a cache. When the delivery of the fat matrix components is completed, the next extraction is performed. When the single extraction volume does not meet the preset threshold but the extraction automatically ends, the extracted fat matrix components are delivered to the cache, and the extraction process ends to obtain the fat matrix components.

12. The method for automatically obtaining fat matrix components according to claim 10, wherein: The extraction also includes fat matrix component detection. Each time the extraction is performed, it is detected whether there is fat matrix component in the extraction pipeline. When the detection result is fat matrix component, the extraction is continued; when the detection result is waste liquid, the extraction is terminated.

13. The method for automatically obtaining fat matrix components according to claim 12, wherein: The fat matrix component detection is to determine the type of liquid in the pipeline by monitoring the real-time voltage obtained by the extraction pipeline. When the real-time voltage is less than a preset voltage, it is determined to be a fat matrix component and the extraction continues. When the real-time voltage is greater than the preset voltage, it is determined to be waste liquid and the extraction ends.

14. The method for automatically obtaining fat matrix components according to claim 10, wherein: The method further comprises pumping back the waste liquid. After the fat matrix components are extracted, waste liquid exists in the extraction pipeline, and the waste liquid is pumped back, wherein the waste liquid is pumped back at a low speed.

15. The method for automatically obtaining fat matrix components according to claim 10, wherein: The method further includes automatically washing the fat matrix components, washing the fat matrix components to obtain washed fat matrix components, wherein the washing is divided into two steps: enrichment and resuspension; the fat matrix components in the fat matrix component liquid are extracted by the enrichment, and the fat matrix components are washed by resuspension, and the enrichment and resuspension are performed in sequence, wherein the enrichment is repeated k times and the resuspension is repeated m times to obtain the washed fat matrix, where k and m are natural numbers greater than 1.

16. The method for automatically obtaining fat matrix components according to claim 15, wherein: The enrichment and extraction separates the fat matrix component and waste liquid in the fat matrix component liquid by high-speed rotation, and the waste liquid is discharged through a pipeline to obtain the fat matrix component.

17. The method for automatically obtaining fat matrix components according to claim 15, wherein: The number of enrichments in the method is equal to the number of extractions in the method for automatically obtaining fat matrix components.

18. The method for automatically obtaining fat matrix components according to claim 15, wherein: The resuspension includes two parts: shaking and centrifugation. The specific steps are: Step 1: Get fat cleaning solution; Step 2: The fat washing liquid is collected and enriched with the fat matrix components, and then subjected to oscillation and washing to obtain a mixed liquid; wherein the oscillation and washing are performed by rotating at a low speed; Step 3: Separate the washed fat matrix component and the washing waste liquid in the mixed solution by centrifugation, and discharge the washing waste liquid through a pipeline to obtain the washed fat matrix component.

19. A device for fat washing, fat matrix acquisition and washing, wherein: Leakage test after pipeline installation, including: A pipeline to be tested, wherein the pipeline to be tested is composed of M interconnected pipeline paths, where M is a natural number greater than 1; a pump passing through the pipeline to be tested and used to provide power; The pressure detection module includes L pressure sensors, where L is a natural number greater than or equal to 2. The pipeline passes through the pressure detection module, wherein the pipeline passes through a first pipeline pressure sensor, a pump, and a second pipeline pressure sensor in sequence. The gas in the pipeline flows as the pump rotates. The pressure sensor detects the change in pipeline pressure to determine the sealing of the pipeline, including: when the pump rotates forward, the first pipeline pressure sensor detects that the pressure in the pipeline decreases and the second pipeline pressure sensor detects that the pipeline pressure increases, and the pipeline is determined to be in a sealed state; or when the pump rotates reversely, the first pipeline pressure sensor detects that the pressure in the pipeline increases and the second pipeline pressure sensor detects that the pressure in the pipeline decreases, and the pipeline is determined to be in a sealed state; the pressure detection module also includes blockage detection; the blockage detection is that after the test liquid flows through the pipeline, the first pipeline pressure sensor detects the pressure of the pipeline liquid inlet port, and the second pipeline pressure sensor detects the pressure of the pipeline liquid outlet port. When the pressure of the pipeline outlet port increases or the pressure of the pipeline inlet port decreases, the pipeline is determined to be blocked; when the pressure remains unchanged, the pipeline is determined to be in a normal state; The photoelectric monitoring module includes an optical sensor, a voltage feedback port, a monitoring port, and a comparator. The photoelectric monitoring module is used to detect whether the pipeline is correctly installed. The pipeline passes through the photoelectric monitoring module. The optical sensor performs pipeline detection to obtain a feedback voltage, and the feedback voltage is fed back to the voltage feedback port. The comparator then compares the feedback voltage value of the voltage feedback port with the preset threshold value of the monitoring port. When the feedback voltage is greater than the preset threshold value, it is determined that the pipeline is correctly installed. Otherwise, it is unsuccessful, and a prompt sound and prompt message are used to remind the user to reinstall it.

20. The device for fat washing, fat matrix acquisition and washing according to claim 19, wherein: The pipeline to be tested includes a liquid inlet pipeline and a liquid discharge pipeline. The device also includes a fat cleaning container. The liquid inlet pipeline and the liquid discharge pipeline are connected to the fat cleaning container. The path for transporting liquid in the pipeline to be tested also includes a stop valve. The liquid inlet pipeline includes a first stop valve and a fifth stop valve, and the path of the liquid discharge pipeline includes a second stop valve and a fourth stop valve. The pump is located between the first stop valve and the fifth stop valve of the liquid inlet pipeline. The pipeline through which the fat cleaning liquid passes passes through the first stop valve, the pump, and the fifth stop valve in sequence; the pump is located between the second stop valve and the fourth stop valve of the liquid discharge pipeline; the pipeline through which the waste liquid passes passes through the second stop valve, the pump, and the fourth stop valve in sequence; the liquid discharge pipeline passes through the photoelectric monitoring module, and the liquid discharge pipeline through which the waste liquid passes passes through the photoelectric control module, the second stop valve, the pump, and the fourth stop valve in sequence; After the photoelectric monitoring module detects that the pipeline is correctly installed and the pressure sensor determines that the pipeline is in a sealed state, the fat is injected into the fat cleaning container and the fat cleaning liquid is input through the liquid inlet pipeline. The fat cleaning container is vibrated and shaken to clean the fat to obtain the cleaned fat and cleaning waste liquid. The cleaning waste liquid is discharged through the drainage pipeline and the waste liquid feedback voltage when the waste liquid flows through the drainage pipeline is detected by the photoelectric monitoring module to determine whether the fat is cleaned; wherein, the waste liquid feedback voltage of the voltage feedback port is compared with the waste liquid monitoring threshold of the monitoring port by a comparator. When the waste liquid feedback voltage is greater than the waste liquid monitoring threshold, it is determined that the fat is not cleaned, and the fat cleaning liquid is input through the pipeline to continue the next cleaning. Otherwise, it is determined that the fat is cleaned and the current cleaning is the final cleaning.

21. The device for fat washing, fat matrix acquisition and washing according to claim 19, wherein: The device also includes a device for unblocking blockages. During the waste liquid discharge process, the first pressure sensor of the pipeline detects that the pressure of the discharge pipeline has decreased and the pump stops providing pressure to discharge the waste liquid. The device enters the steps of forward unblocking and / or reverse unblocking; when the unblocking is forward unblocking, the stop valve on the liquid inlet pipeline is opened to form a liquid inlet passage, and then the pump is started to provide pressure to pressurize the fat cleaning liquid to flush the mesh filter to complete the unblocking; when the unblocking is reverse unblocking, the pump is started to provide pressure to pressurize the waste liquid back to reversely flush the mesh filter to complete the unblocking.

22. The device for fat washing, fat matrix acquisition and washing according to claim 19, wherein: The pipeline also includes a liquid extraction pipeline, through which fat matrix components are output. When the device extracts fat matrix, the photoelectric control module is located in the liquid extraction pipeline path. The fat matrix passes through the photoelectric control module, the second stop valve, the pump, and the sixth stop valve in the liquid extraction pipeline in sequence. The comparator compares the real-time voltage with the preset voltage to determine the type of liquid in the pipeline. When the feedback voltage is lower than the preset voltage threshold, it is determined to be fat matrix components. When the feedback voltage is higher than the preset voltage threshold, it is determined to be waste liquid.

23. The device for fat washing, fat matrix acquisition and washing according to claim 19, wherein: The device also includes a buffer container and a waste liquid container, wherein the extracted fat matrix component is stored in the buffer container, and the discharged waste liquid is stored in the waste liquid container; the buffer container is a centrifugal chamber, including a static module, and the static module is composed of a liquid inlet, a liquid outlet, and an in-chamber delivery pipeline. The fat matrix component liquid enters the centrifugal chamber through the liquid inlet and enters the interior of the centrifugal chamber along the in-chamber delivery pipeline; The centrifugal chamber further comprises a rotating module, the rotating module comprising a rotating central axis, a centrifugal chamber, and a storage area; N centrifugal chambers are connected with the rotating central axis as the center, and each end of the N centrifugal chambers is connected to a storage area, where N is a natural number greater than or equal to 1; wherein the centrifugal chambers are connected to the storage area at an inclined angle; a delivery pipeline of the static module is connected to the N centrifugal chambers, and the fat matrix component liquid is delivered to the centrifugal chambers through the delivery pipeline of the static module, and the fat matrix component liquid is cleaned by rotating the centrifugal chambers in the rotating module; The pipeline also includes a liquid outlet pipeline, which is connected to the liquid outlet. The waste liquid in the cabin is discharged through the liquid outlet pipeline. The waste liquid in the cabin passes through the third stop valve, the pump, and the fourth stop valve in sequence to the waste liquid container through the liquid outlet pipeline.

24. The device for fat washing, fat matrix acquisition and washing according to claim 23, wherein: The cleaning includes enrichment, through which separated fat matrix components and waste liquid in the cabin are obtained. The waste liquid in the cabin is transported to the liquid outlet through a transport pipeline and then discharged through the liquid outlet pipeline to obtain the fat matrix components.

25. The device for fat washing, fat matrix acquisition and washing according to claim 24, wherein: The cleaning further includes resuspending the fat matrix component. The resuspending step comprises: first delivering a fat cleaning liquid into the interior of the centrifugal chamber through the liquid inlet and the in-chamber delivery pipeline, oscillating and cleaning the fat matrix component to obtain cleaned fat matrix components and cleaning waste liquid, then centrifuging to collect the fat matrix components into a storage area connected to the centrifugal chamber to obtain the cleaned fat matrix components, and discharging the cleaning waste liquid through the liquid outlet and the liquid outlet pipeline.

26. A computer program product comprising a memory, a processor, and a computer program or instructions stored on the memory, wherein: The computer program or instructions are executed by a processor to implement the method for detecting the sealing performance of a pipeline after installation as described in any one of claims 1-3, or the method for automatically cleaning fat as described in any one of claims 4-9, or the method for automatically obtaining fat matrix components as described in any one of claims 10-18.

27. A computer device comprising a memory, a processor, and a computer program or instruction stored on the memory, wherein: The computer program or instructions are executed by a processor to implement the method for detecting the sealing performance of a pipeline after installation as described in any one of claims 1-3, or to implement the method for automatically cleaning fat as described in any one of claims 4-9, or to implement the method for automatically obtaining fat matrix components as described in any one of claims 10-18.

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