Remote delivery of fluids

Abstract

An apparatus for delivering a drug to a patient includes: a first syringe with a first proximal end, a first distal end, and a first interior volume; a separating member slidably engaged within the first interior volume, thereby dividing the first interior volume into a drug dispensing chamber and a driving fluid receiving chamber; a fluid driving device including a second proximal end, a second distal end, a second interior volume, and a driver; and a first fluid communication channel between the second distal end of the fluid driving device and the first proximal end of the first syringe. The driver is engaged within the second interior volume to urge a driving fluid from the second interior volume into the driving fluid receiving chamber, thereby translating the separating member and urging drug from the drug dispensing chamber to a patient. MEI 48239367V.1 26

Description

KAD6017USPSP1-138616-00301 REMOTE DELIVERY OF FLUIDS TECHNICAL FIELD

[0001] BACKGROUND

[0002] BRIEF DESCRIPTION OF THE DRAWINGS

[0003] more embodiments described herein and

[0004] delivery system according to one or more embodiments described herein.

[0005] drug delivery system according to one or more embodiments described herein.

[0006] according to one or more embodiments described herein.KAD6017USPSP1-138616-00301

[0007] system according to one or more embodiments described herein.

[0008] FIGS. one or more embodiments described herein.

[0009] or more embodiments described herein.

[0010] embodiments described herein.

[0011] embodiments described herein.

[0012] FIG. 9 embodiments described herein.

[0013] FIGS. lOA and lOB depict an example of a separating member of a remote drug delivery system according to one or more embodiments described herein.

[0014] system according to one or more embodiments described herein.

[0015] syringe of a remote drug delivery system according to one or more embodiments described

[0016] FIGS. 13A-13G depict use of a remote drug delivery system according to one or more embodiments described herein.

[0017] drug delivery system according to one or more embodiments described herein.KAD6017USPSP1-138616-00301

[0018] a remote drug delivery system according to one or more embodiments described herein.

[0019] FIG. 16 depicts an example apparatus according to one or more embodiments

[0020] DESCRIPTION OF EMBODIMENTS

[0021]

[0022] As discovered by the inventors, a remote drug delivery system may employ a remoteKAD6017USPSP1-138616-00301

[0023] In some embodiments, a remote drug delivery system may include a syringe with a

[0024] or more embodiments described herein. The remote drug delivery system 1000 may include a remote dnig delivery system 1000 according to one or more embodiments described herein.

[0025] 21 may be divided into a drug dispensing chamber or volume 28 in fluid communication with anKAD6017USPSP1-138616-00301

[0026] The drug dispensing chamber 28 and the driving fluid receiving chamber 30 may be

[0027] KAD6017USPSP1-138616-00301

[0028] (CSTD) 34, which may include a CSTD outlet port 36. The injection appai’atus 70 may beKAD6017USPSP1-138616-00301

[0029] communication channel 50. As depicted in FIG. 2A, the fluid communication channel 50 200. The syringe pump 200 may include a pump controlled by a programmable device for driving the second syringe 40. The syringe pump 200 may include a programmable device (e.g., a computer apparatus 250). As an example, the computer apparatus 250 may be a computer apparatus 700 of FIG. 14, discussed further below. In some embodiments, the second syringe 40 may be operated manually.

[0030] may be used. In some embodiments, a force may be applied to the second syringe 40 to urgeKAD6017USPSP1-138616-00301

[0031] delivery system 1000 according to one or more embodiments described herein. The steps of the

[0032] Referring to FIG. 5A, the dose of the drug may be compounded and placed into vial 100. The may include overage, may be withdrawn from vial 100, through CSTD 34, through the outlet at

[0033]

[0034] KAD6017USPSP1-138616-00301 and further defining the drug dispensing chamber 28. The plunger stem 25 may be separated engagement mechanism between plunger stem 25 and seal 26..

[0035]

[0036] the syringe pump 200, which may be controlled by the computer apparatus 250, may be attached or engaged to the second syringe 40. Computer apparatus 250 may further perform variousKAD6017USPSP1-138616-00301

[0037]

[0038]

[0039] In some embodiments, the injection apparatus 70 may be primed from a vial holdingKAD6017USPSP1-138616-00301

[0040]

[0041]

[0042] KAD6017USPSP1-138616-00301

[0043]

[0044]

[0045] FIGS. lOA and lOB depict examples of a separating member 26 of the remote drug delivery system 1000 according to one or more embodiments described herein. In some

[0046] drug delivery system 1000 according to one or more embodiments described herein. The distalKAD6017USPSP1-138616-00301 end 24’ may include a piercing member 500 aligned to pierce the separating member 26. The of openings or apertures 506. The tapered top 508 may be aligned with the separating member tapered top 508 may include an opening 506. The piercing member 500 may form a fluid member 500 may be positioned within the drug dispensing chamber 28 to pierce the separating member 26 thereby mixing the drug and the driving fluid. The separating member 26 may

[0047] embodiments described herein. When the separating member 26 reaches the distal end 24’ of the

[0048] FIGS. 13A-13G depict use of the remote drug delivery system 1000 according to one or more embodiments described herein, where the remote drug delivery system 1000 includes aKAD6017USPSP1-138616-00301

[0049] Referring to FIG. 13A, a piercing member 500 and a CSTD 34 may be attached to

[0050]

[0051] Referring to FIG. 13C, the third syringe 90 may be removed from the CSTD 34.

[0052]

[0053]

[0054]

[0055] KAD6017USPSP1-138616-00301

[0056] drug delivery system according to one or more embodiments described herein. FIGS. 14A andKAD6017USPSP1-138616-00301

[0057] of a remote drug delivery system according to one or more embodiments described herein. As

[0058] FIG. 16 depicts an example computer apparatus 700 for use with the embodiments an example, block 412 and / or block 416 of FIG. 4 may be performed by a computer, such as apparatus 700. The apparatus 700 may include one or more processors 702, memory 703, one or

[0059] In some embodiments, based on input 701, the one or more processors 702 may one or more embodiments described herein. As an example, input 701 may be user input. As an communication with the apparatus 700. The input 701 may be received in conjunction with one

[0060] information to the memory 703. The memory 703 may store instructions that, when executed by the one or more processors 702, implement one or more embodiments described herein. TheKAD6017USPSP1-138616-00301 memory 703 may be a non-transitory computer readable medium (or a non-traiisitory processor remote dmg delivery systems, wherein when executed by a processor (such as one or more

[0061] embodiments of the remote drug delivery system described herein. The output device(s) 705 may

[0062] processors 702); and memory (such as memory 703) accessible by the one or more processors,

[0063] The memory 703 may be a non-transitory processor readable medium containing a

[0064] given embodiment (e.g., the given embodiment described in independent claim format) may beKAD6017USPSP1-138616-00301 combined with other embodiments (described in independent claim format or dependent claim

[0065]

Claims

KAD6017USPSP1-138616-00301 CLAIMS 1. An apparatus for delivering a drug to a patient, comprising:

2. The apparatus of claim 1, wherein the fluid driving device is a second syringe andKAD6017USPSP1-138616-00301 4. The apparatus of claim 2, wherein the separating member maintains a liquid-tight 5. The apparatus of claim 4, further including a second fluid communication channel The apparatus of claim 5, further including a pump controlled by a programmable 8. The apparatus of claim 7, wherein the programmable device comprises: one or more processors; and memory accessible by the one or more processors, the memory storing to perform a method comprising:KAD6017USPSP1-138616-00301 13. The apparatus of claim 12, wherein the separating member prevents mixing of the 14. The apparatus of claim 12, wherein the separating member includes a duck bill 15. The appai'atus of claim 12, wherein the piercing member comprises a secondKAD6017USPSP1-138616-00301 16. The apparatus of claim 15, wherein the separating member includes a score or a 17. The apparatus of claim 12, wherein the piercing member comprises:

18. A method of delivering drug to a patient with a drug delivery system, the drugKAD6017USPSP1-138616-00301 19. The method of claim 18, wherein the fluid driving device is a second syringe and 21. The method of claim 19, wherein the separating member maintains a liquid-tight 22. The method of claim 21, wherein the drug delivery system further comprises a 23. The method of claim 22, wherein the injection apparatus includes a needle or aKAD6017USPSP1-138616-00301 26. The method of claim 25, wherein the drug delivery system further comprises a 27. The method of claim 18, wherein the drug delivery system further comprises a communication channel.

28. The method of claim 27, wherein the pump is controlled by a programmable 29. The method of claim 28, further comprising:KAD6017USPSP1-138616-00301 30. The method of claim 18, wherein the drug delivery system further comprises a chamber to pierce the separating member.

31. The method of claim 30, further comprising piercing the separating member by 32. The method of claim 31, wherein, after the separating member is pierced by the 33. The method of claim 31, further comprising, after the separating member is 34. The method of claim 31, further comprising, after the separating member is 35. A method, machine, manufacture, and / or system substantially as shown and

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