Inhibitors of lactate dehydrogenase, compositions comprising the inhibitor, and methods of use thereof
WO2025242056A1PCT designated stage Publication Date: 2025-11-27META PHARM (HK) LTD +1
Patent Information
- Application Number
- PCT/CN2025/095853
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-05-20
- Filing Date
- 2025-05-19
- Publication Date
- 2025-11-27
Smart Images
Figure PCTCN2025095853-FTAPPB-I100001 
Figure PCTCN2025095853-FTAPPB-I100002 
Figure PCTCN2025095853-FTAPPB-I100003
Abstract
The present disclosure provides novel substituted pyrrole compounds that can serve as inhibitors of lactate dehydrogenase, pharmaceutical compositions, comprising at least one of such novel substituted pyrrole compounds, and methods of using at least one of such compounds or compositions in treating or preventing diseases associated with lactate dehydrogenase activities, such as primary hyperoxaluria.
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Citation Information
Patent Citations
Small molecule inhibitors of lactate dehydrogenase and methods of use thereof
WO2016109559A2
1 h-pyrazol-1 -YL-thiazoles as inhibitors of lactate dehydrogenase and methods of use thereof
WO2018005807A1
Substituted pyrazolyl compounds and methods of use thereof
WO2021234543A1
Substituted pyrazolyl compounds and methods of use thereof
WO2021234547A1
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