Repairing and Anti-aging functional composition and repairing and Anti-aging cosmetic product

By using a compound composition of lemon balm flower/leaf/stem water, sea fennel callus culture filtrate, phytol and sodium carboxymethyl β-glucan, the problem of high irritation of highly effective anti-aging ingredients in existing technologies has been solved, achieving a gentle and effective anti-aging effect on the skin.

WO2025246997A1PCT designated stage Publication Date: 2025-12-04SHANGHAI ZUNYA IND CO LTD
View PDF 8 Cites 0 Cited by

Patent Information

Application Number
PCT/CN2025/095764
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-05-27
Filing Date
2025-05-19
Publication Date
2025-12-04

AI Technical Summary

Technical Problem

Existing high-efficiency anti-aging ingredients such as retinol, vitamin C, and acids are highly irritating and unsuitable for people with damaged skin barriers, while plant extracts containing anti-aging effects are not very effective.

Method used

This product uses a compound composition of lemon balm/leaf/stem water, sea fennel callus culture filtrate, phytol, and sodium carboxymethyl β-glucan to provide a gentle anti-aging effect and enhance the skin barrier repair function through synergistic action.

Benefits of technology

It significantly improves anti-aging effects, reduces irritation, and enhances the skin barrier's repair capabilities, making it suitable for people with damaged skin barriers.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure PCTCN2025095764-APPB-I100001
    Figure PCTCN2025095764-APPB-I100001
  • Figure PCTCN2025095764-APPB-I100002
    Figure PCTCN2025095764-APPB-I100002
  • Figure PCTCN2025095764-APPB-I100003
    Figure PCTCN2025095764-APPB-I100003
Patent Text Reader

Abstract

A repairing and anti-aging functional composition and a repairing and anti-aging cosmetic product. Active ingredients contained in the repairing and anti-aging functional composition include the following components: 0.994-7.952 parts by weight of Melissa officinalis flower / leaf / stem water, 1-3 parts by weight of Crithmum maritimum callus culture filtrate, 0.0015-0.005 parts by weight of phytol, and 0.9-4.5 parts by weight of sodium carboxymethyl β-glucan. The repairing and anti-aging cosmetic product is prepared from the described repairing and anti-aging composition and cosmetic excipient.
Need to check novelty before this filing date? Find Prior Art

Description

A repairing and anti-aging composition and a repairing and anti-aging cosmetic. Technical Field

[0001] This application relates to the technical field of daily cosmetics, and more specifically, to a repair and anti-aging composition and a repair and anti-aging cosmetic. Background Technology

[0002] Skin aging is a continuous and gradual natural physiological process that directly affects the appearance and function of the skin. To slow down aging, various anti-aging and wrinkle-reducing products have emerged. However, due to factors such as sun exposure, people's skin may experience varying degrees of barrier damage. Those with damaged skin barriers cannot use ingredients with strong anti-aging effects. Therefore, to address the anti-aging issues of people with damaged skin barriers, it is essential to prioritize the gentleness of anti-aging ingredients to achieve skin anti-aging while maintaining skin stability. Technical issues

[0003] While currently available high-efficiency anti-aging ingredients such as retinol, vitamin C, and acids have significant anti-aging effects, they are also quite irritating and unsuitable for people with damaged skin barriers. Plant extracts containing anti-aging properties are gentler, but their anti-aging effects are limited. Technical solutions

[0004] In order to ensure that the product has excellent anti-aging effects while reducing irritation and making it suitable for people with damaged skin barriers, this application provides a repair and anti-aging composition and a repair and anti-aging cosmetic.

[0005] In a first aspect, this application provides a composition with repairing and anti-aging effects, employing the following technical solution:

[0006] A repairing and anti-aging composition comprising the following active ingredients in parts by weight:

[0007] Lemon balm / leaf / stem water content: 0.994-7.952 parts;

[0008] 1-3 portions of filtrate from sea fennel callus culture;

[0009] Phytol 0.0015-0.005 parts;

[0010] Sodium carboxymethyl β-glucan, 0.9-4.5 parts.

[0011] By adopting the above technical solution, the combination of the above four components is less irritating than potent anti-aging components, has the effect of repairing the skin barrier, and has a better anti-aging effect.

[0012] Lemon balm is a plant containing rare aromatic essential oil molecules. Lemon balm / leaf / stem water contains aromatic components such as β-caryophyllene, citral, citronellol, and caryophyllin, which have excellent calming, soothing, and anti-inflammatory effects. In addition, lemon balm / leaf / stem water also contains polyphenols and flavonoids. Flavonoids can promote collagen synthesis, thereby reducing the appearance of fine lines, fading existing wrinkles, repairing damaged skin, and promoting skin cell regeneration.

[0013] Sea fennel callus culture filtrate is rich in a variety of nutrients needed for growth and metabolism, which can promote the repair of dermal cells and the regeneration of epidermal cells, and promote the production of skin collagen.

[0014] Phytol is mainly found in plant lipids and is a major component of plant cell walls. The phytol used in this application is mainly derived from the extract of Physcomitrella patens. It can help restore the health of epidermal cell nuclei, enhance the skin's ability to adapt to the environment, strengthen the skin barrier quality, and improve the skin's adaptability to changes in the external environment.

[0015] Lemon balm flower / leaf / stem water and sea fennel callus culture filtrate provide basic anti-aging effects, but the anti-aging effect of the combination of the four is significantly enhanced. The reason for this may be that lemon balm flower / leaf / stem water contains polyphenols and flavonoids. Flavonoids inhibit the free calcium in cells. 2+ Increased levels of sodium carboxymethyl β-glucan inhibit lipoxygenase LOX, thereby reducing free radical production, while sodium carboxymethyl β-glucan can inhibit Ca2+. 2+ The endogenous flow significantly enhances the antioxidant effect of flavonoids, thereby significantly improving the anti-aging effect.

[0016] Optionally, the active ingredients in the repairing and anti-aging composition may also include black tea seed oil.

[0017] By employing the above-mentioned technical solution: Black tea seed oil is an extract of the flower, leaf, and vine of the black tea plant, rich in oils and glycerols. It can be used to moisturize the skin and also as a fragrance. Rich in omega-3 / omega-6 fatty acids, it helps rebuild a damaged skin barrier and alleviate allergic reactions. It has a good relieving effect on eczema, strengthens the skin barrier to improve its ability to resist inflammation, reduces the worsening of rosacea, prevents inflammation, and improves the overall appearance of skin with rosacea.

[0018] Optionally, the active ingredients in the repairing and anti-aging composition may also include unsaponifiables from sunflower seed oil.

[0019] By employing the above-mentioned technical solution, unsaponifiable matter from sunflower seed oil, a refined product, is rich in various vitamins, essential fatty acids, and antioxidants. It can penetrate deep into the skin's layers, replenishing the skin's nutritional needs, promoting metabolism, and enhancing skin vitality. Its active ingredients, such as linoleic acid, help fade pigmentation deposits and inhibit melanin production, showing significant effects in improving age spots. Furthermore, unsaponifiable matter from sunflower seed oil can strengthen the skin barrier function and delay aging.

[0020] Optionally, the active ingredients in the repairing and anti-aging composition may also include sunflower seed oil.

[0021] By adopting the above technical solution, sunflower seed oil has skin moisturizing effect, anti-inflammatory effect of activating oxidase receptors and promoting skin wound healing, inhibitory effect on tyrosinase, and can also play a whitening role.

[0022] Secondly, this application provides a repair and anti-aging cosmetic product, which adopts the following technical solution:

[0023] A repairing and anti-aging cosmetic, wherein the cosmetic is prepared using the repairing and anti-aging composition and cosmetic excipients described above.

[0024] By adopting the above technical solution, the addition of repairing and anti-aging compositions enhances the corresponding efficacy of cosmetics without causing irritation.

[0025] Optionally, the amount of the repair and anti-aging composition added to the cosmetic is 1-10%.

[0026] By adopting the above technical solution, when the amount of the repair and anti-aging composition added is within the above range, it can be used to improve the efficacy of cosmetics. When the amount is further increased, the improvement in repair and anti-aging efficacy is small. Considering factors such as cost, it is necessary to control the upper limit of the amount of the repair and anti-aging composition to 10%.

[0027] Optionally, the cosmetic product is one of the following: skin care water, lotion, serum, cream, facial mask liquid, and gel.

[0028] By adopting the above technical solution, it has a wide range of applications.

[0029] Optionally, the cosmetic is a cream, wherein the cosmetic excipients in the cream are: water, glycerin, allantoin, 1,2-pentanediol, carbomer, xanthan gum, sodium stearoyl glutamate, oil, lactobionic acid, levulinic acid, and sodium levulinate.

[0030] Optionally, the oil is one or more of C10-18 fatty acid triglycerides, castor seed oil, sweet almond oil, and shea butter. Beneficial effects

[0031] In summary, this application has the following beneficial effects:

[0032] 1. The repair and anti-aging composition of this application contains four products with active ingredients: lemon balm / leaf / stem water, sea fennel callus culture filtrate, phytol, and sodium carboxymethyl β-glucan. It not only has a better repair effect, but also, due to the further addition of sodium carboxymethyl β-glucan to the anti-aging effects of lemon balm / leaf / stem water and sea fennel callus culture filtrate, it exerts a significant anti-aging effect through the synergistic effect between the four active substances and the synergistic effect between sodium carboxymethyl β-glucan and lemon balm / leaf / stem water.

[0033] 2. The repair and anti-aging composition of this application has good effects and good stability, and can be used in a wide range of cosmetics, with a wide range of applications;

[0034] 3. The repair and anti-aging cosmetic of this application incorporates the repair and anti-aging composition prepared in this application and limits its dosage to achieve superior repair and anti-aging effects. Embodiments of the present invention

[0035] The present application will be further described in detail below with reference to the embodiments.

[0036] The lemon balm / leaf / stem water used in this application was collected from GOLGEMMA, trade name LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008, and contains, by weight percentage, 99.4% lemon balm / leaf / stem water, 0.048% dehydroacetic acid, 0.522% benzyl alcohol, and 0.03% water;

[0037] Sea fennel callus culture filtrate was collected from Biotech Marine, trade name: CELTOSOME CRITHMUM MARITIMUM, purity 100%;

[0038] Phytol was purchased from MIBELLE, trade name: MOSSCELLTEC No.1 (0571), and contains 0.05% phytol, 5.995% water, and 94% isomalto by weight.

[0039] Sodium carboxymethyl β-glucan was sourced from MIBELLE, under the trade name CM-GLUCAN GRANULATE (0713), and contained 90% sodium carboxymethyl β-glucan, 5% water, and 5% ethanol by weight percentage.

[0040] The nigricans seed oil, sunflower seed oil unsaponifiables, and sunflower seed oil are sourced from RAHN Company under the trade name DEFENSIL PLUS. By weight percentage, they contain 78.41% octyl dodecyl alcohol, 17.5% nigricans seed oil, 2.5% sunflower seed oil unsaponifiables, 0.5% cardiopsis halicachabum flower / leaf / vine extract, 0.5% tocopherol (vitamin E), 0.5% sunflower seed oil, and 0.09% rosemary officinalis leaf extract.

[0041] Retinol was sourced from IRA under the trade name RETINOL 33,000 Ul / g CYCLOSYSTEM COMPLEX (25001), and by weight percentage contained 7.1% hydroxypropyl cyclodextrin, 1.03% retinol, 18.1% water, 15.61% caprylic / capric triglycerides, 0.2% tocopherol (vitamin E), 57.69% polysorbate-20, 0.2% sodium metabisulfite, and 0.07% butylated hydroxytoluene.

[0042] The levulinic acid and sodium levulinate were sourced from EVONIK under the trade name DERMOSOFT 700B, and contained, by weight percentage, 40% levulinic acid, 23% sodium levulinate, 17% glycerol, and 20% water.

[0043] Allantoin was sourced from Shandong Ailitong New Materials Co., Ltd., under the trade name Allantoin (Ailitong), with a purity of 100%.

[0044] 1,2-Pentanediol was sourced from SYMRISE, trade name HYDROLITE 5 GREEN, 100% purity;

[0045] Carbomer is sourced from LUBRIZOL ADVANCED MATERIALS, under the trade name CARBOPOL ULTREZ 10 POLYMER, and is 100% pure.

[0046] Xanthan gum is sourced from CP KELCO US, INC., and is marketed under the brand name KELTROL® CG-T XANTHAN GUM, with a purity of 100%.

[0047] Sodium stearoyl glutamate was sourced from BASF, under the trade name EUMULGIN SG, with a purity of 100%.

[0048] Lactobionic acid was sourced from SPEC CHEM INDUSTRY INC., under the trade name SPECKARE LBA (110034), and was 100% pure.

[0049] C10-18 fatty acid triglycerides were sourced from GATTEFORSE, trade name LIPOCIRE A SG (5838), 100% purity;

[0050] Castor seed oil is sourced from Gustav Hees, trade name Rodicarre S, 100% purity;

[0051] The sweet almond oil is sourced from A&A FRATELLI PARODI SPA, trade name PARYOL 480 MR (MP 013392), 100% pure.

[0052] The avocado oil is sourced from A&A FRATELLI PARODI SPA, trade name PARYOL 218 BK / R (MP 017491), and is 100% pure.

[0053] Preparation Example 1

[0054] A repairing and anti-aging composition is prepared by conventionally mixing LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008, CELTOSOME CRITHMUM MARITIMUM, MOSSCELLTEC No.1 (0571), and CM-GLUCAN GRANULATE (0713) in a weight ratio of 1:1:3:1. The contents of lemon balm / leaf / stem water, sea fennel callus culture filtrate, phytol, and sodium carboxymethyl β-glucan are shown in Table 1.

[0055] Preparation Example 2

[0056] A repairing and anti-aging composition is prepared by conventionally mixing LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008, CELTOSOME CRITHMUM MARITIMUM, MOSSCELLTEC No.1 (0571), and CM-GLUCAN GRANULATE (0713) in a weight ratio of 4.5:2:6:3. The contents of lemon balm / leaf / stem water, sea fennel callus culture filtrate, phytol, and sodium carboxymethyl β-glucan are shown in Table 1.

[0057] Preparation Example 3

[0058] A repairing and anti-aging composition is prepared by conventionally mixing LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008, CELTOSOME CRITHMUM MARITIMUM, MOSSCELLTEC No.1 (0571), and CM-GLUCAN GRANULATE (0713) in a weight ratio of 8:3:10:5. The contents of lemon balm / leaf / stem water, sea fennel callus culture filtrate, phytol, and sodium carboxymethyl β-glucan are shown in Table 1.

[0059] Comparative Preparation Example 1

[0060] A repairing and anti-aging composition is prepared by conventionally mixing LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008, CELTOSOME CRITHMUM MARITIMUM, MOSSCELLTEC No.1 (0571), and CM-GLUCAN GRANULATE (0713) in a weight ratio of 4:0.5:2:0.5. The contents of lemon balm / leaf / stem water, sea fennel callus culture filtrate, phytol, and sodium carboxymethyl β-glucan are shown in Table 1.

[0061] Comparative Preparation Example 2

[0062] A repairing and anti-aging composition is prepared by conventionally mixing LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008, CELTOSOME CRITHMUM MARITIMUM, MOSSCELLTEC No.1 (0571), and CM-GLUCAN GRANULATE (0713) in a weight ratio of 4:3.5:15:5.5. The contents of lemon balm / leaf / stem water, sea fennel callus culture filtrate, phytol, and sodium carboxymethyl β-glucan are shown in Table 1.

[0063] Table 1 (Unit: kg)

[0064]

[0065] Comparative preparation example 3

[0066] A repairing and anti-aging composition differs from Preparation Example 2 in that it contains only LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008, and does not contain sea fennel callus culture filtrate, phytol, or sodium carboxymethyl β-glucan.

[0067] Comparative preparation example 4

[0068] A repair and anti-aging composition, which differs from Preparation Example 2 in that it contains only CM-GLUCAN GRANULATE (0713), that is, it does not contain lemon balm / leaf / stem water, sea fennel callus culture filtrate, or phytol.

[0069] Comparative preparation example 5

[0070] A repairing and anti-aging composition, which differs from Preparation Example 2 in that it does not contain LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008, that is, it does not contain lemon balm / leaf / stem water.

[0071] Comparative preparation example 6

[0072] A repair and anti-aging composition, which differs from Preparation Example 2 in that it does not contain CM-GLUCAN GRANULATE (0713), that is, it does not contain sodium carboxymethyl β-glucan.

[0073] Preparation Example 4

[0074] A repairing and anti-aging composition is prepared by conventionally mixing LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008, CELTOSOME CRITHMUM MARITIMUM, MOSSCELLTEC No.1 (0571), CM-GLUCAN GRANULATE (0713), and DEFENSIL PLUS in a weight ratio of 4.5:2:6:3:2.

[0075] Preparation Example 5

[0076] A repairing and anti-aging composition is prepared by conventionally mixing LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008, CELTOSOME CRITHMUM MARITIMUM, MOSSCELLTEC No.1 (0571), CM-GLUCAN GRANULATE (0713), and DEFENSIL PLUS in a weight ratio of 4.5:2:6:3:6.

[0077] Preparation Example 6

[0078] A repairing and anti-aging composition is prepared by conventionally mixing LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008, CELTOSOME CRITHMUM MARITIMUM, MOSSCELLTEC No.1 (0571), CM-GLUCAN GRANULATE (0713), and DEFENSIL PLUS in a weight ratio of 4.5:2:6:3:10.

[0079] Anti-aging test

[0080] 1. Determination of hydroxyl radical scavenging rate

[0081] (1) Reagent preparation

[0082] FeSO4·7H2O solution: Accurately weigh 2.224g of FeSO4·7H2O, dissolve it in 100mL of deionized water, mix well, take 10mL of the solution, and make up to 100mL to prepare an 8mmol / L FeSO4·7H2O solution.

[0083] H2O2 solution: Weigh 68 mg of 30% H2O2 solution, mix it with 1 mL of deionized water, and make up to 100 mL to prepare a 6 mmol / L H2O2 solution.

[0084] Sodium salicylate solution: Weigh 0.3202g of sodium salicylate, dissolve it in an appropriate amount of deionized water, and make up to 100mL to prepare a 20mmol / L sodium salicylate solution.

[0085] Repair and anti-aging efficacy composition sample solution: Weigh 0.5g of the repair and anti-aging efficacy composition from each preparation example or comparative preparation example and dissolve it in an appropriate amount of deionized water. Add water to make up to 100 mL to prepare a stock solution of anti-aging composition with a mass concentration of 5mg / mL. Then, use the stock solution to prepare a sample solution with a mass concentration of 0.5mg / mL for later use.

[0086] (2) Hydroxyl radical scavenging rate test

[0087] Add the reagents to the four test tubes according to the dosage shown in Table 3, and heat them in a 37°C water bath for 1 hour. Then, take an appropriate amount of solution and add it to a quartz cuvette. Measure the absorbance at a wavelength of 510 nm. Perform three parallel tests for each experimental group.

[0088] Table 3. Dosage of each reagent added in the hydroxyl radical scavenging test.

[0089]

[0090] The hydroxyl radical scavenging rate is calculated as [1-(A1-A2) / A0]×100%.

[0091] In the formula, A0 is the absorbance of group A0, A1 is the absorbance of group A1, and A2 is the absorbance of group A2.

[0092] Test Results

[0093] Referring to the above method for testing hydroxyl radical scavenging rate, the test results of the prepared example and the comparative prepared example are included in the table below.

[0094] Table 4 Test Results

[0095]

[0096] According to Table 4, the test results of Preparation Example 2 and Comparative Preparation Examples 3 and 4 were compared. The sample solution contained lemon balm / leaf / stem water, sea fennel callus culture filtrate, phytol, and sodium carboxymethyl β-glucan. The scavenging rate of hydroxyl radicals was significantly higher than that when lemon balm / leaf / stem water or sodium carboxymethyl β-glucan was used alone, indicating that the combination of the four has a certain synergistic anti-aging effect. Moreover, the anti-aging and repairing effect of the composition of this application is significantly better than that of the plant extract (lemon balm / leaf / stem water).

[0097] According to Table 4, the difference between Preparation Examples 5 and 6 and Preparation Example 2 is that the absence of lemon balm / leaf / stem water or sodium carboxymethyl β-glucan significantly reduced the hydroxyl radical scavenging rate, indicating that the anti-aging effect is significant only when both are present.

[0098] Examples 1-3, Comparative Examples 1-2

[0099] A cosmetic product, which is a cream, has the following components and their corresponding weights as shown in Table 5, and is prepared by the following steps:

[0100] Water, glycerol, allantoin, 1,2-pentanediol, carbomer, xanthan gum, and sodium stearoyl glutamate were mixed and stirred at 80°C and 500 rpm for 20 min to obtain the first aqueous phase. Oils (C10-18 fatty acid triglycerides, castor seed oil, sweet almond oil, and shea butter) were mixed and stirred at 80°C and 500 rpm for 10 min to obtain the oil phase. Lactobionic acid and DERMOSOFT 700B were mixed using conventional stirring to obtain the second aqueous phase.

[0101] Add the oil phase to the first aqueous phase, stir and mix well, then stop heating and continue stirring until room temperature. Then add the repair and anti-aging composition (prepared from Preparation Example 1) and the second aqueous phase, stir and mix well to obtain the final product.

[0102] Table 5. Components and their weights (kg) in Examples 1-3 and Comparative Examples 1-2

[0103]

[0104] Comparative Example 3

[0105] A cosmetic product, which is a cream, differs from Example 2 in that an equal amount of RETINOL 33,000 Ul / g CYCLOSYSTEM COMPLEX (25001) (containing 1.03% retinol) is used instead of the repair and anti-aging composition.

[0106] Examples 4-8, Comparative Examples 4-9

[0107] A cosmetic product, which is a cream, differs from Example 2 in that the use of the repair and anti-aging composition is as shown in the table below, but the amount of the repair and anti-aging composition in the cream remains unchanged.

[0108] Table 6. Usage of the repair and anti-aging compositions in Examples 4-8 and Comparative Examples 4-9

[0109]

[0110] Performance testing

[0111] The cosmetics prepared in the examples and comparative examples were subjected to the following performance tests, and the test results are recorded in Table 7.

[0112] Detection methods

[0113] Sixty-eight individuals with wrinkles and healthy, undamaged skin, aged 35-40, were selected and randomly divided into 17 groups of four. Each group used the cosmetics prepared in Examples 1-8 and Comparative Examples 1-9, respectively. Usage: After cleansing, subjects applied 0.5g of the cosmetic to a 3*3cm area of ​​their cheek. The application was left for 10 minutes, then washed off. The cosmetic was applied twice, once at 9:00 AM and once at 6:00 PM. The following tests were performed on the same skin area:

[0114] 1. Wrinkle area change test:

[0115] The wrinkle area of ​​the subjects was measured using the VISIA-CR facial image analyzer from the United States before the subjects used the cosmetics. The initial value was recorded. After 7 days of continuous use, the wrinkle area was measured again and recorded as the termination value. Finally, the change rate of wrinkle area was calculated as follows: change rate = (initial value - termination value) / initial value. The larger the change rate, the better the anti-aging effect of the cosmetics.

[0116] 1. Transepidermal water loss (TEWL) change test: The transepidermal water loss of the test subjects was measured before the use of cosmetics using the German CK Tewameter™ Hex skin analyzer. The initial value was recorded. After 7 days of continuous use, the transepidermal water loss was measured again and recorded as the termination value. Finally, the change rate of transepidermal water loss (TEWL) was calculated. Change rate = (initial value - termination value) / initial value. The larger the change rate, the better the repair effect of the cosmetic.

[0117] Sixty-eight individuals with wrinkles and healthy, undamaged skin, aged 35-40, were selected and divided into 17 groups of four. Each group used cosmetics prepared according to Examples 1-8 and Comparative Examples 1-9, respectively, and underwent the following tests:

[0118] 1. Irritation test: Following the closed patch test method, the cosmetic was removed after 2 hours. Skin reactions were observed at 0.5h, 24h, and 48h after the patch test. Skin irritation reaction was scored according to the skin reaction grading standard in 5.3.2.1.3 of "Procedures and Methods for Safety Evaluation of Cosmetics" GB7919-1987, with 0 points indicating the least irritation and 8 points indicating the most irritation.

[0119] Table 7 Performance Test Results

[0120]

[0121] Based on Table 7, the test results of Examples 1-3 and Comparative Example 1 were compared. The wrinkle area change rate and TEWL change rate of the creams in Examples 1-3 increased with increasing dosage of the repair and anti-aging composition. In Comparative Example 1, the data for the cream without the repair and anti-aging composition decreased significantly, indicating that the repair and anti-aging composition enhanced the repair and anti-aging effects of the cosmetics. However, the improvement in effect slowed down when the dosage of the repair and anti-aging composition was increased from 5% to 10%. Considering overall cost, the dosage in Example 2 was deemed the optimal dosage.

[0122] According to Table 7, the difference between Comparative Example 3 and Example 2 is that an equal amount of a product containing retinol was used instead of the repair and anti-aging composition. The repair and anti-aging effects were similar, but the irritation was extremely high.

[0123] Based on Table 7, Comparative Examples 6-9 are compared with Example 2. The differences between each comparative example and Example 2 are as follows:

[0124] Comparative Example 6 used an equal amount of LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008 (containing lemon balm / leaf / stem water, but excluding sea fennel callus culture filtrate, phytol, and sodium carboxymethyl β-glucan) to replace the repair and anti-aging composition; Comparative Example 7 used an equal amount of CM-GLUCAN GRANULATE. (0713) (Contains sodium carboxymethyl β-glucan, but does not contain lemon balm / leaf / stem water, sea fennel callus culture filtrate, or phytol) as a substitute for the repair and anti-aging composition; the repair and anti-aging composition of Comparative Example 8 does not contain lemon balm / leaf / stem water; the repair and anti-aging composition of Comparative Example 9 does not contain sodium carboxymethyl β-glucan; as shown in Table 7, the wrinkle area change rate and TEWL change rate of the face creams prepared in Comparative Examples 6-9 decreased significantly, indicating that the cream has a significant effect only when the four components of the repair and anti-aging composition of this application are compounded.

[0125] It should be noted that the oils in this application may be selected from one or more of C10-18 fatty acid triglycerides, castor seed oil, sweet almond oil and shea butter for compounding. This application only briefly introduces the compounding of four of them as an example.

[0126] 4. Stability test: The cosmetics were stored at -18°C and 48°C for 30 days, and no unstable conditions such as oil deterioration were observed, indicating good stability.

[0127] This specific embodiment is merely an explanation of this application and is not intended to limit it. After reading this specification, those skilled in the art can make modifications to this embodiment without contributing any inventive step, but such modifications are protected by patent law as long as they fall within the scope of the claims of this application.

Claims

1. A composition with repairing and anti-aging effects, characterized in that, The active ingredients include the following components in parts by weight: Lemon balm / leaf / stem water content: 0.994-7.952 parts; 1-3 portions of filtrate from sea fennel callus culture; Phytol 0.0015-0.005 parts; Sodium carboxymethyl β-glucan, 0.9-4.5 parts.

2. The repairing and anti-aging composition according to claim 1, characterized in that: The active ingredients in the repairing and anti-aging composition also include black tea seed oil.

3. The repairing and anti-aging composition according to claim 1, characterized in that: The active ingredients in the repairing and anti-aging composition also include unsaponifiables from sunflower seed oil.

4. The repairing and anti-aging composition according to claim 1, characterized in that: The active ingredients in the repairing and anti-aging composition also include sunflower seed oil.

5. A repairing and anti-aging cosmetic, characterized in that, The cosmetic is prepared using the repair and anti-aging composition and cosmetic excipients as described in any one of claims 1-4.

6. A repairing and anti-aging cosmetic according to claim 5, characterized in that: In the cosmetic product, the amount of the repair and anti-aging composition added is 1-10%.

7. A repairing and anti-aging cosmetic according to claim 5, characterized in that: The cosmetic product is one of the following: skin care water, lotion, serum, cream, facial mask liquid, and gel.

8. A repairing and anti-aging cosmetic according to claim 7, characterized in that: The cosmetic is a cream, and the cosmetic excipients in the cream are: water, glycerin, allantoin, 1,2-pentanediol, carbomer, xanthan gum, sodium stearoyl glutamate, oil, lactobionic acid, levulinic acid, and sodium levulinate.

9. A repairing and anti-aging cosmetic according to claim 8, characterized in that: The oil is one or more of the following: C10-18 fatty acid triglycerides, castor seed oil, sweet almond oil, and shea butter.

Citation Information

Patent Citations

  • All-effect repair water-optical skin-rejuvenating lotion

    CN105832613A

  • Cosmetic for treating corticosteroid dermatitis, and preparation method thereof

    CN106551893A

  • After-sun remediation facial mask

    CN106806256A

  • Eye mask liquid of marine soothing washing-free eye protection mask and preparation method thereof

    CN108272694A

  • Soothing anti-inflammatory composition, soothing anti-inflammatory cosmetic and preparation method of soothing anti-inflammatory composition and soothing anti-inflammatory cosmetic

    CN115089521A