Acupoint plaster for treating pneumonia and preparation method therefor

Abstract

An acupoint plaster for treating pneumonia and a preparation method therefor, relating to the field of traditional Chinese medicines. A composition used in the acupoint plaster comprises the following components in parts by weight: 10-25 parts of honeysuckle, 7-17 parts of astragalus root, 10-15 parts of silkworm slough, 5-12 parts of weeping forsythia, and 5-10 parts of curcuma wenyujin. Honeysuckle, astragalus root, silkworm slough, weeping forsythia, and curcuma wenyujin are taken as raw materials and are combined to form the composition capable of treating pneumonia, and by means of the combined effect of acupoints, the objectives of warming yang, dispelling cold, and treating pneumonia are achieved by stimulating acupoints Feishu and Tiantu by means of traditional Chinese medicines and stimulating the acupoints by means of the medicines to stimulate meridians and collaterals and regulating qi and blood. Pure traditional Chinese medicine treatment is combined with traditional Chinese medical science diagnosis and acupoint selection, so that the present invention has advantages such as simplicity and easiness in operation, significant efficacy, and few side effects. The preparation method for the acupoint plaster is simple and easy to implement, has low costs, and is suitable for large-scale factory production and application.

Description

Acupoint patch for treating pneumonia and preparation method thereof TECHNICAL FIELD

[0001] The present application relates to the field of traditional Chinese medicine, in particular to an acupoint patch for treating pneumonia and a preparation method thereof. BACKGROUND

[0002] The lung is a canopy, connecting to all meridians, regulating water and liquid, externally combining with skin and hair, and opening to the nose, directly communicating with the weather, and anatomically occupying the highest position of the five Zang organs. People rely on the respiratory function of the lungs to continuously inhale clean air and exhale turbid air, and to expel old and absorb new, combining with the Spleen and Stomach to form "Zongqi" to gather in the chest to regulate the rise and fall of the body's Qi. When external pathogens invade the human body, whether from the mouth and nose or by invading the skin and hair, they are easy to attack the lungs and cause disease. The lung is a clear and empty organ that cannot tolerate evil, and cold and heat diseases in other organs often affect the lung. The lung likes dampness and dislikes dryness, and cannot tolerate cold and heat. Once the lung Qi is damaged, various diseases will arise, such as wind causing panting, cold causing cough, dampness causing phlegm, and fire causing cough. Therefore, the lung plays an important role in maintaining human life and health.

[0003] The clinical manifestations of patients with pneumonia caused by new coronavirus infection are mainly fever, fatigue, and dry cough. Severe patients may develop hypoxia and even life-threatening conditions. Respiratory dysfunction is one of the main symptoms of respiratory system damage after new coronavirus pneumonia, mainly manifested as dyspnea, shortness of breath after exercise, wheezing, chest tightness, and cough with difficulty in expectoration. The main manifestations are restrictive ventilatory dysfunction, decreased diffusion volume with hypoxemia or respiratory failure. The cause of dyspnea and dysfunction in new coronavirus pneumonia is lung lesions caused by new coronavirus infection.

[0004] At present, the treatment methods mainly include intravenous drip and aerosol inhalation, and the treatment effect is systemic, the drug dosage is large, the target is unclear, and the patient is prone to side effects of the drug, and the disease is easily delayed. Therefore, it is an urgent need to seek a safe and effective treatment method for pneumonia.

[0005] SUMMARY

[0006] The purpose of the present application is to provide an acupoint patch for treating pneumonia and a preparation method thereof, in order to solve the above-mentioned treatment difficulties. The present application is based on the theory of traditional Chinese medicine meridians, uses a specific drug formula, and applies acupoint sticking, stimulates the acupoints by drugs, penetrates into the local skin, and then achieves the effect of regulating the balance of Qi and blood in the human body and treating pneumonia.

[0007] To achieve the above-mentioned purpose, the present application provides the following scheme:

[0008] Technical solution one: a kind of acupoint paste composition for treating pneumonia, the acupoint paste composition includes the following components by weight: honeysuckle 10-25 parts, radix astragali 7-17 parts, silkworm chrysalis 10-15 parts, forsythia 5-12 parts and warm turmeric 5-10 parts.

[0009] Further, the acupoint paste composition includes the following components by weight: honeysuckle 15 parts, radix astragali 13 parts, silkworm chrysalis 10 parts, forsythia 7 parts and warm turmeric 6 parts.

[0010] Technical solution two: an acupoint patch for treating pneumonia, comprising the acupoint paste composition.

[0011] Technical solution three: the acupoint paste composition is applied in the preparation of products for treating pneumonia.

[0012] Technical solution four: the acupoint paste composition is applied in the preparation of products for treating pneumonia rehabilitation period dyspnea symptoms and dysfunction.

[0013] Further, the product includes acupoint patch.

[0014] Further, the acupoint of the acupoint patch application includes Feishu and Tiantu.

[0015] Technical solution five: an acupoint patch for pneumonia rehabilitation period, comprising the acupoint paste composition and pharmaceutically acceptable acupoint paste adjuvant.

[0016] Technical solution six: a preparation method of the acupoint patch, comprising the following steps:

[0017] The acupoint paste composition is mixed in a certain proportion, crushed into fine powder; the fine powder is mixed with an appropriate amount of water, stirred into paste; the paste material is evenly coated on the acupoint patch substrate, dried; the dried acupoint patch is cut to make the appropriate size of the patch; the prepared acupoint patch is packaged, and the acupoint patch is obtained.

[0018] Further, the crushing is through 100 mesh sieve.

[0019] The monarch honeysuckle can clear heat and detoxify, anti-inflammatory and swelling, is used for treating exogenous wind-heat or warm disease fever, toxic blood dysentery, carbuncle, sore, laryngalgia, various infectious diseases.

[0020] The minister radix astragali can assist the monarch to have the effect of tonifying qi and ascending yang, consolidating the exterior and stopping sweating, promoting water and reducing swelling, generating saliva and nourishing blood, removing stagnation and relieving arthralgia, removing pus and promoting healing, and promoting healing and generating muscle; radix astragali and honeysuckle can enhance the effect of tonifying qi.

[0021] The assistant silkworm chrysalis has the effects of dispersing wind-heat, benefiting the throat, removing rash, clearing the eyes and relieving convulsions.

[0022] The Chinese medicine Fructus Forsythiae has the effects of clearing heat and detoxifying, and relieving fever, cough and other symptoms caused by pneumonia, and can control infection, enhance immunity and resist bacteria and inflammation.

[0023] The Chinese medicine Radix et Rhizoma Zanthoxyli has the effects of activating blood and relieving pain, promoting qi and relieving depression, clearing heart and blood, and promoting bile and reducing jaundice.

[0024] The present application discloses the following technical effects:

[0025] The acupoint patch provided by the present application adopts Chinese herbal medicine components, has the advantages of safety, effectiveness and no side effects, and is suitable for patients of all ages and physical conditions with pneumonia. Meanwhile, the acupoint patch is convenient to use, and can be operated by patients themselves without the guidance of professional medical staff, greatly improving the convenience and comfort of treatment.

[0026] The present application is applied to the acupoints of Feishu and Tiandu through syndrome differentiation, stimulates the acupoints by the medicine, penetrates into the local skin from outside to inside and from the surface to the inside to directly reach the disease, so as to stimulate the meridians and further regulate the balance of qi and blood in the human body, not only achieving the effects of warming yang, dispelling cold, relieving cough, reducing sputum and relieving asthma, but also having important significance for preventing and treating respiratory diseases. The acupoint patch and the preparation method thereof fully utilize the advantages of traditional Chinese medicine, combine modern preparation technology, and prepare a safe and effective acupoint patch for treating pneumonia. The acupoint patch can quickly relieve the clinical symptoms of pneumonia and improve the quality of life of patients through the dual effects of stimulating acupoints and medicine components. The preparation scheme of the acupoint patch is simple and easy to implement, has low cost, and is suitable for large-scale factory production and application. DETAILED DESCRIPTION

[0027] The various illustrative embodiments of the present application will now be described in detail in connection with the accompanying drawings. This description is not intended to limit the application, but rather to provide an exemplification of certain aspects and features thereof. Thus, those skilled in the art will recognize that modifications and variations can be made while remaining within the spirit and scope of the application.

[0028] It is to be understood that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting. Additionally, the use of the term "about" in relation to a value or a range of values is intended to include each individual intermediate value and each smaller range that falls within the range of values. The upper and lower limits of these smaller ranges can be independently included or excluded from the range.

[0029] Many modifications and variations of this application can be made without departing from its spirit and scope, which is described in the scope of the application. Other implementations of the application will be apparent to those skilled in the art from consideration of the specification and practice of the application disclosed herein. The specification and examples given are exemplary only. It is to be understood that the application is not limited in scope by the specific embodiments described herein. Those skilled in the art will recognize that equivalents for the specific embodiments described herein can be made with the scope and spirit of the application. The terms "comprises", "comprising", "includes", "including", "contains", "containing" or variations thereof do not specify an exhaustive or complete list of elements or steps as they can be subject to revision.

[0030] Example 1

[0031] An acupoint patch for treating pneumonia comprises the following ingredients by weight: honeysuckle 15 parts, astragalus 13 parts, silkworm chrysalis 10 parts, forsythia 7 parts, and warm turmeric 6 parts.

[0032] The preparation method comprises the following steps:

[0033] (1) The above Chinese herbal medicines are mixed according to a certain proportion and crushed into fine powder;

[0034] (2) The fine powder is mixed with an appropriate amount of water and stirred into paste;

[0035] (3) The paste material is evenly coated on the acupoint patch substrate and dried;

[0036] (4) The dried acupoint patch is cut to make patches of appropriate size;

[0037] (5) The prepared acupoint patch is packaged, and the acupoint patch is obtained.

[0038] Example 2

[0039] An acupoint patch for treating pneumonia comprises the following ingredients by weight: honeysuckle 25 parts, astragalus 17 parts, silkworm chrysalis 15 parts, forsythia 12 parts, and warm turmeric 10 parts.

[0040] The preparation method comprises the following steps:

[0041] (1) The above Chinese herbal medicines are mixed according to a certain proportion and crushed into fine powder;

[0042] (2) The fine powder is mixed with an appropriate amount of water and stirred into paste;

[0043] (3) The paste material is evenly coated on the acupoint patch substrate and dried;

[0044] (4) The dried acupoint patch is cut to make patches of appropriate size;

[0045] (5) The prepared acupoint patch is packaged, and the acupoint patch is obtained.

[0046] Example 3

[0047] An acupoint patch for treating pneumonia comprises the following ingredients by weight: honeysuckle 10 parts, astragalus 7 parts, silkworm chrysalis 10 parts, forsythia 5 parts, and warm turmeric 5 parts.

[0048] The preparation method comprises the following steps:

[0049] (1) The above Chinese herbal medicines are mixed according to a certain proportion and crushed into fine powder;

[0050] (2) The fine powder is mixed with an appropriate amount of water and stirred into paste;

[0051] (3) evenly spread the paste on the acupoint paste base material and dry;

[0052] (4) cut the dried acupoint paste into appropriate size patches;

[0053] (5) package the prepared acupoint paste, and the acupoint paste is obtained.

[0054] Comparative Example 1

[0055] The difference from Example 1 is that the acupoint paste of the present comparative example comprises the following components by weight: honeysuckle 30 parts, radix astragali 20 parts, silkworm chrysalis 17 parts, forsythia 14 parts, and warm turmeric 12 parts.

[0056] Comparative Example 2

[0057] The difference from Example 1 is that the acupoint paste of the present comparative example comprises the following components by weight: honeysuckle 28 parts, silkworm chrysalis 10 parts, forsythia 7 parts, and warm turmeric 6 parts.

[0058] Experimental Example 1

[0059] The acupoint pastes prepared in Examples 1-3 and Comparative Examples 1-2 were used for the clinical application effect statistics of treating dyspnea symptoms and dysfunction in the recovery period of novel coronavirus pneumonia.

[0060] 1. Case selection: 600 patients in the recovery period of new coronavirus pneumonia who came to the Second Affiliated Hospital of Guangzhou Medical University for treatment from December 2019 to July 2022 were randomly divided into an experimental group and a control group. The patients complained of fatigue, shortness of breath, chest tightness, poor appetite, and difficulty in urination and defecation.

[0061] 2. Treatment method: In addition to normal rehabilitation treatment, the patients in Experimental Groups 1-3 used the acupoint pastes obtained in Examples 1-3 to apply to the patients' Tianfu and Feishu points, respectively, once a day, and each time for 2 hours of application. The patients in Control Groups 1-2 used the acupoint pastes obtained in Comparative Examples 1-2 to apply to the patients' Tianfu and Feishu points, respectively, once a day, and each time for 2 hours of application. Control Group 3 was a normal rehabilitation treatment plan (the same as the rehabilitation treatment method of the experimental groups), and no acupoint paste was used. The experimental group and the control group were continuously treated for 14 days, and the treatment effect was observed.

[0062] 3. Efficacy determination standard:

[0063] Cure: normal body temperature, disappearance of fatigue, shortness of breath, chest tightness, poor appetite, and normal urination and defecation;

[0064] Effective: normal body temperature, normal urination and defecation, improvement of fatigue and poor appetite, but mild shortness of breath and chest tightness;

[0065] Invalid: body temperature rises, no obvious improvement in clinical symptoms or re-positive.

[0066] 4. Treatment results:

[0067] The total number of patients in each group in Table 1 is 100, and Table 1 is the statistical result of the patients after 14 days of rehabilitation treatment in each group.

[0068] Table 1

[0069] The number of patients who recovered after treatment or care: the number of patients who improved and fully recovered after treatment or care; Cure rate / %: the percentage of the number of patients who fully recovered (i.e. recovered) in the total number of patients receiving a certain treatment or care service; Effective number / person: the number of patients who improved but did not fully recover after treatment or care; Re-positive rate / %: the percentage of the number of patients who again have similar symptoms or positive reactions (such as positive test results) within a certain period of time after receiving a certain treatment or care service;

[0070] According to statistics, the acupoint patch provided by examples 1-3 of the present application greatly reduces the fatigue, shortness of breath, chest tightness and poor appetite of patients in the recovery period of pneumonia, and the majority of patients have normal bowel movements after acupoint patch treatment, with a total effective rate of up to 99%. In the control group, 8-11 people have re-positive, and the effect is significantly worse than that of the experimental group.

[0071] The above-described examples only describe the preferred mode of the present application, and do not limit the scope of the present application. Without departing from the design spirit of the present application, various modifications and improvements to the technical solutions of the present application made by those skilled in the art shall fall within the protection scope determined by the claims of the present application.

Claims

1. A composition for acupoint patch for treating pneumonia, characterized by, The acupoint patch composition comprises the following components in parts by weight: honeysuckle 10-25 parts, astragalus 7-17 parts, silkworm chrysalis 10-15 parts, forsythia 5-12 parts, and warm curcuma 5-10 parts.

2. The composition for acupoint application according to claim 1, wherein The acupoint patch composition comprises the following components in parts by weight: honeysuckle 15 parts, astragalus 13 parts, silkworm chrysalis 10 parts, forsythia 7 parts, and warm curcuma 6 parts.

3. An acupoint patch for treating pneumonia, characterized in that, The acupoint patch composition of claim 1 or 2.

4. Use of the acupoint patch composition of claim 1 or 2 in the preparation of a product for treating pneumonia.

5. Use of the acupoint patch composition of claim 1 or 2 in the preparation of a product for treating dyspnea and dysfunction in the convalescent stage of pneumonia.

6. Use according to claim 4 or 5, wherein the compound is ###0002### The product comprises an acupoint patch.

7. Use according to claim 6, wherein The acupoints to which the acupoint patch is applied comprise Feishu and Tiantu.

8. A point application for pneumonia rehabilitation, characterized in that: The acupoint patch composition of claim 1 or 2 and pharmaceutically acceptable acupoint patch adjuvants.

9. A method for preparing an acupoint patch as described in claim 3, characterized in that, The method comprises the following steps: The acupoint patch composition is mixed in a certain proportion, pulverized into fine powder, mixed with an appropriate amount of water, stirred into paste, uniformly coated on the acupoint patch substrate, dried, cut into patches of appropriate size, and packaged.

10. The production method according to claim 9, wherein The pulverization is through a 100-mesh sieve.

Images