Ternary insecticidal composition comprising a benzoylurea, an avermectin and indoxacarb insecticides

Abstract

The present invention relates to stable synergistic insecticidal composition for synergistic and effective control of various insect pests including entire sucking pest complex.

Description

[0001] TERNARY INSECTICIDAL COMPOSITION COMPRISING A BENZOYLUREA, AN AVERMECTIN AND INDOXACARB INSECTICIDES

[0002] FIELD OF THE INVENTION

[0003] The present invention relates to a stable synergistic insecticidal composition and manufacturing method thereof. More specifically, it relates to a stable synergistic insecticidal composition comprising bio-active amounts of (A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives; (B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives; and (C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives. The present invention further relates to process of preparing a stable synergistic insecticidal composition for synergistic and efficacious control of various insects-pests including entire sucking-pests complex.

[0004] BACKGROUND OF THE INVENTION

[0005] Background description includes information that may be useful in understanding the present invention. It is not an admission that any of the information provided herein is prior art or relevant to the presently claimed invention.

[0006] Bug or Insect pest nuisances are among the most harming adversaries of yields. They cause serious crop harm, bringing about lower crop efficiency. Controlling crop pest populations has been a significant issue, and different conventional and high-level techniques are being utilized to limit the harm brought about by bug bothers. Persistent utilization of pesticides and insect poisons in an uncontrolled and informal way throughout the years has brought about the improvement of obstruction in bug irritations, and this opposition keeps on widening in range against various bug sprays / pesticides. Continuous high-intensity insect spray and pesticide use has brought about other basic issues like the presence of a lot of insect spray deposits in farming items, expanded natural contamination and harm to environmental equilibrium, and disintegrating soundness of purchasers. With the beginning of protection from specific bug / insect pest bothers, there is a need in the craftsmanship for a blend of actives that decline the possibilities of obstruction and works on the range of illness and irritation control.

[0007] It is always preferable to be able to reduce the amounts of chemical agents released into the environment while still ensuring effective pest control. Although insect pest control agent combinations have been studied, a high synergistic action has not always been found. There is however a need for improvement of these combinations. Single active compositions used over a long period of time has resulted in resistance. With the onset of resistance to certain pests, there is a need in the art for a combination of insecticidal actives that decrease the chances of resistance and improves the spectrum of disease and insect pest control.

[0008] Combination of insecticides are used to broaden the spectrum of control of insects, to improve the insect pest control with synergistic effect, reduce dosage, thereby reducing environmental impact, decrease chances of development and management of resistance and to enhance residual control so lesser the number of sprays for crop protections and minimizing the insecticidal load in ecosystem. The combination of insecticides at times demonstrates an additive or synergistic effect that results in an improved control of insect pests.

[0009] There are many combinations of insecticides known in the art for the control of insects and soil borne pests. However, the existing insecticidal combinations often have negative impact on plants and crops such as slow insecticidal metabolism and toxicity. Additionally, they are ineffective against preemergence and postemergence application along with broad spectrum in various crops.

[0010] Moreover, the formulations as known in the prior arts often have detrimental effects on non-target organisms and the environment, raising serious issues related to phytotoxicity, discoloration of leaves and other damages to plants. Compounding these challenges, the natural ageing of plant influences various physiological and biochemical processes, leading to reduced growth, decreased resistance to environmental stresses, and diminished overall health and productivity.

[0011] It is well recognized that prior art formulations vary significantly in their composition and functional performance, and not all provide comparable results in terms of efficacy, stability, shelflife, or safety. Several known formulations in the art have been associated with detrimental effects on non-target organisms and the surrounding environment, including but not limited to phytotoxicity, discoloration of foliage, and other forms of plant damage. These adverse effects are often exacerbated during various stages of plant maturation, adversely influencing physiological and biochemical processes, leading to reduced growth, lower resistance to environmental stressors, and overall decline in plant health and productivity. In contrast, the specific formulation of the present invention is designed to overcome such limitations by providing enhanced bioefficacy, improved stability, extended shelf life, and reduced risk to non-target organisms and the environment. The synergistic combination of active components and excipients in the present composition contributes to improved delivery, controlled release, and superior performance under field conditions, thereby addressing long-standing deficiencies of prior art solutions. Reference can be made to CN104855409A, which discloses the pesticidal composition containing tolfenpyrad and indoxacarb is characterized by containing 10-40% of tolfenpyrad, 10-40% of indoxacarb, a wetting dispersant, a suspending agent or a water dispersible granule composition prepared from auxiliary agents such as a filler and the like.

[0012] Further reference can be made to CN106465721A, which discloses an insecticidal composition containing novaluron and tolfenpyrad, which comprises common auxiliary agents, novaluron and tolfenpyrad, and is characterized in that: the ratio of parts by weight of novaluron to tolfenpyrad is 1: 5-5: 1.

[0013] With the onset of resistance to certain insects, there is a need in the art for a combination of insecticidal actives that decreases chances of resistance and improves the spectrum of disease and insect pest control.

[0014] Benzoylurea class of insecticide is an Inhibitor of chitin biosynthesis, affecting CHS1. It acts to disrupt moulting and egg hatch, and thus act as insect growth regulators. They act by inhibiting chitin synthase, preventing the formation of chitin in the insect's body. It is active against many types of insect pests such as lepidoptera coleoptera, diptera, etc as well as being used against termites and animal health pests such as fleas.

[0015] Further, avermectins are derived from a family of macrocyclic lactones insecticides and are a specialized class of chemical agents known for their unique mode of action against various insects-pests. The avermectins block the transmission of electrical activity in invertebrate nerve and muscle cells mostly by enhancing the effects of glutamate at the glutamate -gated chloride channel that is specific to protostome invertebrates, with minor effects on gamma-aminobutyric acid receptors. This causes an influx of chloride ions into the cells, leading to hyperpolarisation and subsequent paralysis of invertebrate neuromuscular systems; comparable doses are not toxic for mammals because they do not possess protostome-specific glutamate-gated chloride channels. The most common avermectins are abamectin, doramectin, emamectin, emamectin benzoate, eprinomectin, ivermectin, selamectin that shows to have and effective insecticidal action. Their efficacy in managing pest populations, combined with their environmentally friendly profile, makes avermectin insecticides a valuable tool in integrated pest management programs. They offer a promising solution for sustainable agriculture and helps to mitigate resistance development in pest populations.

[0016] Moreover, Indoxacarb belongs to an oxadiazine class of insecticide chemically known as methyl (S)-N-{ [7- chloro-2,3,4a,5-tetrahydro-4a-(methoxycarbonyl)indeno[l,2-e][l,3,4]oxadiazin-2-yl]carbonyl}-4'- (trifhioromethoxy)carbanilate or methyl (S)-7-chloro-2,3,4a,5-tetrahydro-2-{(methoxycarbonyl)[4- (trifhjoromethoxy)phenyl]carbamoyl}indeno[l,2-e][l,3,4]oxadiazine-4a-carboxylate. It is an insecticide for use on a wide range of crops such as Cotton; Brassicas; Sweet corn; Lettuce; Fruiting vegetables; Fruit including apples, pears, cherries, etc to control certain Lepidoptera, cockroaches and ants, etc. It is a Voltagedependent sodium channel blocker.

[0017] The present invention satisfies the existing needs, as well as others, and generally overcomes the deficiencies found in the prior art.

[0018] The present invention composition is synergistic, efficacious, environmentally friendly, simple to formulate, stable and is safe to use.

[0019] Thus, a insecticidal composition of the present invention aims to overcome the problems of the prior art and provides a stable synergistic insecticidal composition comprising bioactive amounts of (A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives; (B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives; and (C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives for synergistic and effective control of various insects pests including sucking pests complex.

[0020] The present invention also provides a novel method of preparing composition of present invention, which is stable as well as provide desired bio-efficacy, synergy. Embodiments of the present invention may therefore ameliorate one or more of the above-mentioned problems.

[0021] OBJECTIVES AND ADVANTAGES OF THE INVENTION

[0022] The main objective of present invention is to provide a novel and effective stable synergistic insecticidal composition demonstrating high efficacy and to provide complete protection to crops and plants against insect-pests including entire sucking-pests complex.

[0023] It is another objective of the present invention to provide improved, stable and ready to use stable insecticidal composition having synergistic and superior properties for effective control of insect pests including sucking pests complex such as Beet armyworm, Fire ants; Cockroaches; Caterpillars, etc.

[0024] Another objective of the present invention is to provide a stable synergistic insecticidal composition comprising (A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives; (B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives; and (C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives. Another objective of the present invention is to provide a stable synergistic insecticidal composition which provides broad spectrum control of insect pests including their eggs and larvae leading to lower rounds of sprays in a crop cycle.

[0025] Another objective of the present invention is to provide a synergistic insecticidal composition for the control of insect pests including but not limited to thrips, mites, stem borer, chewing pests and entire sucking pests complex, which are resistant to existing insecticidal compositions and have prolonged insect pest control.

[0026] Another objective of the present invention is to further reduce the costs of pest management operations and thus improvement in benefit: cost ratio. It is further another objective of the present invention to provide a novel and effective synergistic insecticidal composition which is active against all life stages of major plant insects including chewing pests and entire sucking pests’ complex.

[0027] It is another objective of the present invention to provide a novel and effective synergistic insecticidal composition which is ideal for insect’s resistance management and enhanced disease control and which uses lesser amounts of the actives in the composition as compared to the actives when used alone.

[0028] It is another objective of the present invention to provide a novel and effective synergistic insecticidal composition that provides immediate effect and long -term insect pest control.

[0029] A further objective of the present invention is to provide a method for insect pest control that is both effective in the short and long term and which is stable and can be easily formulated.

[0030] It is another objective of the present invention to provide stable and ready to use composition having synergistic and superior properties compared to prior art compositions or mixtures or formulations.

[0031] Another objective of the present invention is to provide a process for the preparation of aforementioned synergistic insecticidal composition.

[0032] Another objective of the present invention is to provide synergistic composition that promote plant health and increases plant yield in the field and which is simple, easy and convenient to carry out its application on crops, plants and is environmentally safe, possesses broad spectrum bio-efficacy, is non-phytotoxic. It is yet another objective of the present invention to provide a novel and effective synergistic insecticidal composition, which has improved stability during the desired shelf life.

[0033] Yet another objective of the present invention is to provide a process for the preparation of a stable synergistic insecticidal composition comprising (A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives; (B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives; and (C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives .

[0034] It is yet another objective of the present invention is to provide a stable synergistic insecticidal composition that provides effective immediate and long-term effective control and knock down of insect pests including sucking pests complex at all developmental stages of insects such as egg, nymph, larva, pupa, and adult.

[0035] It is yet another objective of the present invention to provide a synergistic insecticidal composition which prevents ageing effect and discoloration of plants leaves and that promotes plant health, growth and thus increases plant / crop yield in the field and is environmentally safe, possesses broad spectrum bio-efficacy, is non-phytotoxic.

[0036] Some or all these and other objects of the invention can be achieved by way of the invention described hereinafter.

[0037] ADVANTAGES:

[0038] 1. The stable synergistic insecticidal composition of present invention has broad spectrum activity against sucking complex pests including but not limited to Beet armyworm, Fire ants; Cockroaches; Caterpillars, etc.

[0039] 2. The stable synergistic insecticidal composition of the present invention has anti-ageing effect on plants and crops and is effective against insect pests including sucking pests complex at all developmental stages of insects such as egg, nymph, larva, pupa, and adult.

[0040] 3. The stable synergistic insecticidal composition of the present invention prevents dis-coloration of leaves and also enhances tenderness in plants and crops.

[0041] 4. The stable synergistic insecticidal composition of the present invention has high controlling effects against existing insects resistant to chemicals, and no chemical damage against plants is observed and is thus, economically beneficial to the farmers as it provides better yield in of the crop with less no. of sprays. 5. The stable synergistic insecticidal composition of present invention is storage stable and shows no phytotoxicity effect and is environmentally friendly and is highly active against diseases in the soil caused by various insect pests including those that mostly occur in the early stages of plant development.

[0042] SUMMARY OF THE INVENTION

[0043] Accordingly, the main aspect of the present is to provide a stable synergistic insecticidal composition having high insects-pests including entire sucking-pests complex control efficacy.

[0044] Accordingly, the present invention relates to a stable synergistic insecticidal composition comprising bioactive amounts of (A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives; (B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives; and (C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives. The present invention further relates to process of preparing a stable synergistic insecticidal composition for synergistic and efficacious control of various insects-pests including entire sucking-pests complex.

[0045] In an embodiment, the present invention provides a stable synergistic insecticidal composition comprising bioactive amounts of:

[0046] A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives;

[0047] B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives; and

[0048] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives.

[0049] In another aspect, the present invention provides a stable synergistic insecticidal composition comprising:

[0050] A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives;

[0051] B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives;

[0052] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives; and

[0053] D) One or more agrochemically acceptable excipients. In one another aspect, the present invention provides a stable synergistic insecticidal composition comprising:

[0054] A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives;

[0055] B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives;

[0056] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives; and

[0057] D) At least one or more additives.

[0058] In one another aspect, the present invention provides a stable synergistic insecticidal composition comprising:

[0059] A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives;

[0060] B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives;

[0061] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives; and

[0062] D) At least one or more additives selected from Urea clathrate, Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof.

[0063] In one another aspect, the present invention provides a stable synergistic insecticidal composition comprising:

[0064] A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives;

[0065] B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives;

[0066] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives;

[0067] D) At least one or more additives selected from Urea clathrate, Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof; and

[0068] E) One or more agrochemically acceptable excipients.

[0069] In one another aspect, the present invention provides a stable synergistic insecticidal composition comprising: A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition;

[0070] B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1 -90% by weight of the composition; and

[0071] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition.

[0072] In one another aspect, the present invention provides a stable synergistic insecticidal composition comprising:

[0073] A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition;

[0074] B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1 -90% by weight of the composition;

[0075] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition; and

[0076] D) one or more agrochemically acceptable excipients.

[0077] In one another aspect, the present invention provides a stable synergistic insecticidal composition comprising:

[0078] A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition;

[0079] B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1 -90% by weight of the composition;

[0080] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition; and D) At least one or more additives selected from Urea clathrate, Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof, in the range of 0.01-20% by weight of the composition.

[0081] In one another aspect, the present invention provides a stable synergistic insecticidal composition comprising:

[0082] A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition;

[0083] B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1 -90% by weight of the composition;

[0084] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1 -90% by weight of the composition;

[0085] D) At least one or more additives selected from Urea clathrate, Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof, in the range of 0.01-20% by weight of the composition; and

[0086] E) One or more agrochemically acceptable excipients.

[0087] In one another preferred aspect, the present invention provides a stable synergistic insecticidal composition comprising:

[0088] A) Novaluron or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1 -90% by weight of the composition;

[0089] B) Emamectin benzoate in the range of 0.1-90% by weight of the composition; and

[0090] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition.

[0091] In yet another aspect, the present invention provides a process for preparation of the stable synergistic insecticidal composition comprising:

[0092] A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives; B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives; and

[0093] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives.

[0094] In another aspect, the present synergistic insecticidal composition is stable and has enhanced shelf life and effectively control wide range of insect pests in various crops.

[0095] In another aspect, the present invention provides a stable synergistic insecticidal composition which has enhanced efficacy and penetration capacity.

[0096] DETAILED DESCRIPTION OF THE INVENTION

[0097] In describing the embodiments of the invention, specific terminology is resorted for sake of clarity. However, it is not intended that the invention be limited to specific terms so selected and it is to be understood that each specific term includes all technical equivalents that operate in a similar manner to accomplish a similar purpose.

[0098] Discussed below are some representative embodiments of the present invention. The invention in its broader aspects is not limited to the specific details and representative methods.

[0099] All technical and scientific terms used herein have the same meanings as commonly understood by someone ordinarily skilled in the art to which the present subject matter belongs.

[0100] The terminology used, in the present disclosure, is only for the purpose of explaining a particular embodiment and such terminology shall not be considered to limit the scope of the present disclosure.

[0101] As used in the present disclosure, the forms "a,” "an," and "the" may be intended to include the plural forms as well, unless the context clearly suggests otherwise. Thus, for example, reference to a composition containing “a compound” includes a mixture of two or more compounds. It should also be noted that the term “or” is generally employed in its sense including “and / or” unless the content clearly dictates otherwise.

[0102] The terms "comprises", "comprising", “including”, and “having” are open ended transitional phrases and therefore specify the presence of stated features, integers, steps, operations, elements, but do not forbid the presence or addition of one or more other features, integers, steps, operations, elements, components, and / or groups thereof. The particular order of steps disclosed in the method and process of the present disclosure is not to be construed as necessarily requiring their performance as described or illustrated. It is also to be understood that additional or alternative steps may be employed.

[0103] Variations or modifications to the composition of this invention, within the scope of the invention, may occur to those skilled in the art upon reviewing the disclosure herein. Such variations or modifications are well within the spirit of this invention.

[0104] The expression of various quantities in terms of “% w / w” or “%” means the percentage by weight, relative to the weight of the total solution or composition unless otherwise specified.

[0105] The term “active ingredient” (a.i.) or “active agent” or “active” used herein refers to that component of the composition responsible for control of various insects-pests at the same time.

[0106] The term “crop” shall include a multitude of desired crop plants or an individual crop plant growing at a locus.

[0107] The term “synergistic”, as used herein, refers to the combined action of two or more active agents blended together and administered conjointly that is greater than the sum of their individual effects.

[0108] “Bioactive amounts” as mentioned herein means that amount which, when applied for treatment of crops, is sufficient to give effect in such treatment.

[0109] The term “control” means to inhibit the ability of insect pests to survive, grow, feed and / or reproduce, or to limit the insect pests’ related damage or loss in crop plants. To “control” insect pests may or may not mean killing the insects although, it preferably means killing the insect pests.

[0110] The term “health of a plant” or “plant health” is defined as a condition of the plant and / or its products. As a result of the improved health; yield, plant vigour, quality and tolerance to abiotic or biotic stress is increased. As a result, the health of a plant is increased even in the absence of pest pressure.

[0111] Accordingly, in an especially preferred embodiment according to the invention, the health of a plant is increased both in the presence and absence of biotic or abiotic stress factors. An increase in plant vigor may for example result in an increased yield and / or tolerance to abiotic or biotic stress.

[0112] One indicator for the condition of the plant is the yield. “Yield” is to be understood as any plant product of economic value that is produced by the plant such as grains, fruits, vegetables, nuts, grains, seeds, wood (e.g., in the case of silviculture plants) or even flowers (e.g. in the case of gardening plants, ornamentals). The plant products may in addition be further utilized and / or processed after harvesting.

[0113] In another preferred embodiment of the invention, the yield of the plants treated according to the method of the invention, is increased synergistically.

[0114] In another especially preferred embodiment of the invention, the plant vigour of the treated plant is increased. In another preferred embodiment of the invention, the plant vigour of the plants treated according to the composition of the present invention is increased synergistically.

[0115] Another indicator for the condition of the plant is the “quality” of a plant and / or its products.

[0116] In an especially preferred embodiment of the invention, the quality of the treated plant is increased.

[0117] In another preferred embodiment of the invention, the quality of the plants treated according to the method of the invention, is increased synergistically.

[0118] The term rain fastness refers to the ability of a substance to remain effective after being applied to a surface and then exposed to rainfall or irrigation. In other words, it measures how well the substance adheres to the target surface and resists being washed away by water. A low rain fastness indicates that it may be washed off or diluted by rainfall, reducing its efficacy.

[0119] The term "Increased uptake of active ingredient" refers to the enhanced absorption or penetration of the active component of a substance into the target organism or plant. This increased uptake can lead to greater effectiveness of the product in controlling various insects-pests including sucking pests at the same time. It may occur through various mechanisms, such as improved formulation, adjuvants that enhance penetration, or modifications to the active ingredient itself to facilitate absorption. Overall, increased uptake of the active ingredient results in improved performance of the product in achieving its intended purpose.

[0120] The term “benefit: cost” refers to a ratio used in a cost-benefit analysis to summarize the overall relationship between the relative costs and benefits of a proposed composition. If a treatment has a benefit -cost ratio greater than 1.0, the treatment is expected to deliver a positive and better outcome.

[0121] In one embodiment of the present invention, the yield of the treated plant is increased.

[0122] In another embodiment of the present invention, there is synergistic and efficacious control of various insectpests affecting the plants and crops. Another embodiment of the present invention, includes within its scope, all possible salts, esters and derivatives of the active ingredients of the composition.

[0123] It is also to be understood that the terminology used herein is for the purpose of describing particular embodiments of the invention only and is not intended to limit the scope of the invention in any manner. The use of examples anywhere in this specification including examples of any terms discussed herein is illustrative only, and in no way limits the scope and meaning of the invention or of any exemplified term. Likewise, the invention is not limited to various embodiments given in this specification.

[0124] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. In the case of conflict, the present document, including definitions will control.

[0125] The composition or formulation according to the present invention has a reduced or zero phytotoxicity with respect to agricultural crops. This results in the present invention effective and possible in the selective control of insects -pest’s control.

[0126] In an embodiment, the stable synergistic insecticidal composition or formulation has a reduced or zero phytotoxicity with respect to important agricultural crops. This results in the present invention effective and possible in the selective control of insect-pests’.

[0127] It has been observed by the inventors of the present invention that the composition of present invention not only provides synergistic effect but also provides anti-aging effect to the crops or plants to which it is applied. In addition, the stable synergistic insecticidal composition of the present invention is effective against all developmental stages of insect pests including egg, nymph, larva, pupa, and adult.

[0128] In an embodiment, the present invention provides a stable synergistic insecticidal composition comprising:

[0129] A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives;

[0130] B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives; and

[0131] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives. In another embodiment, the present invention provides a stable synergistic insecticidal composition comprising:

[0132] A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives;

[0133] B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives;

[0134] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives; and

[0135] D) One or more agrochemically acceptable excipients.

[0136] In one another embodiment, the present invention provides a stable synergistic insecticidal composition comprising:

[0137] A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives;

[0138] B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives;

[0139] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives; and

[0140] D) At least one or more additives.

[0141] In one another embodiment, the present invention provides a stable synergistic insecticidal composition comprising:

[0142] A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives;

[0143] B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives;

[0144] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives; and

[0145] D) At least one or more additives selected from Urea clathrate, Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof. In one another embodiment, the present invention provides a stable synergistic insecticidal composition comprising:

[0146] A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives;

[0147] B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives;

[0148] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives;

[0149] D) At least one or more additives selected from Urea clathrate, Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof; and

[0150] E) One or more agrochemically acceptable excipients.

[0151] In yet another embodiment, the present invention provides a stable synergistic insecticidal composition comprising:

[0152] A) Novaluron or its agrochemically acceptable salts, esters or its derivatives;

[0153] B) Emamectin or its agrochemically acceptable salts, esters or its derivatives; and

[0154] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives.

[0155] In one another embodiment, the present invention provides a stable synergistic insecticidal composition comprising:

[0156] A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition;

[0157] B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition; and

[0158] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition.

[0159] In one another embodiment, the present invention provides a stable synergistic insecticidal composition comprising: A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition;

[0160] B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1 -90% by weight of the composition;

[0161] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition; and

[0162] D) one or more agrochemically acceptable excipients.

[0163] In one another embodiment, the present invention provides a stable synergistic insecticidal composition comprising:

[0164] A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition;

[0165] B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1 -90% by weight of the composition;

[0166] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition; and

[0167] D) At least one or more additives selected from Urea clathrate, Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof, in the range of 0.01-20% by weight of the composition.

[0168] In one another embodiment, the present invention provides a stable synergistic insecticidal composition comprising:

[0169] A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition; B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition;

[0170] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition;

[0171] D) At least one or more additives selected from Urea clathrate, Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof, in the range of 0.01-20% by weight of the composition; and

[0172] E) One or more agrochemically acceptable excipients.

[0173] In another embodiment, the present invention provides a stable synergistic insecticidal composition comprising:

[0174] A) Novaluron or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1 -90% by weight of the composition;

[0175] B) Emamectin or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition; and

[0176] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition.

[0177] In another embodiment, the present invention provides a stable synergistic insecticidal composition comprising:

[0178] A) Novaluron or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1 -90% by weight of the composition;

[0179] B) Emamectin or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition;

[0180] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition; and

[0181] D) one or more agrochemically acceptable excipients. In another embodiment, the present invention provides a stable synergistic insecticidal composition comprising:

[0182] A) Novaluron or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1 -90% by weight of the composition;

[0183] B) Emamectin or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition;

[0184] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition;

[0185] D) At least one or more additives selected from Urea clathrate, Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof, in the range of 0.01-20% by weight of the composition; and

[0186] E) One or more agrochemically acceptable excipients.

[0187] In yet another embodiment, the present invention provides a process for preparation of the stable synergistic insecticidal composition comprising:

[0188] A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives;

[0189] B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives; and

[0190] C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives.

[0191] In an especially preferred embodiment of the invention, the yield of the treated plant is increased.

[0192] In another preferred embodiment of the invention, the yield of the plants treated using the composition of the present invention, is increased.

[0193] The present invention includes within its scope, all possible salts, esters and derivatives or any other modified forms including polymorphic forms, of the active ingredients of the composition.

[0194] In an embodiment, each individual row appearing in the table below represents the combinations in an embodiment of the present invention.

[0195]

[0196] In another embodiment, the stable synergistic insecticidal composition of the present invention controls various insects including their eggs or larvae in field crops, vegetables, fruits, oil seed and pulses, horticulture & forestry, veterinary, etc.

[0197] In another embodiment of the present invention, the present stable synergistic insecticidal composition can be applied as a foliar spray, soil drenching, seed dressing, application as paste to the targeted plants / trees, broadcasting, etc. In yet another embodiment of the present invention, the present stable synergistic insecticidal composition can be applied as a foliar spray to various plants and crops including cotton, chilli, tomato, rice, wheat, paddy, soya bean, red gram, pulses and vegetables including but not limited to okra, sugar beet, egg-plants or brinjal, lettuce, iceberg lettuce, pepper, cucumber, cauliflower squash, melon, bean, dry-beans, sugarcane, black gram, peas, leek, garlic, onion, cabbage, carrot, tuber such as sugar cane, tobacco, coffee, turf and forage, cruciferous, cucurbits, grapevines, pepper, fodder beet, apple, tea, oil seed rape, bengal gram, pigeon pea, pansy, impatiens, petunia, ornamental plants including roses and geranium, etc. In another embodiment of the present invention, the present stable synergistic insecticidal composition can be used against but not limited to chewing pests and sucking pests complex including but not limited to American Bollworm (Helicoverpa armigera), Tobacco caterpillar (Spodoptera litura), Diamond back moth, Fruit borer, Tobacco Caterpillar, Pod borer, fruit borer, Anopheles stephensi, Aedes aegypti, Culex quinquefasciatus, Anopheles subpictus, shoot borer, stem borer, spotted pod borer, Diamond back moth, Tobacco leaf eating caterpillar, Bollworms, Mites, Tea looper, Green semi looper, pod borer, Girdle beetle & Tobacco caterpillar, Red spider mites (Tetranychus urticae), European Red Mite and Spotted Red Spider Mite, Yellow Stem Borer (Scirpophaga incertulas), Leaf Folder (Cnaphalocrosis medinalis), Pod borer (Heliothis armigera), Gram pod borer (Helicoverpa armigera), Black gram pod borer complex (Etiella zinckenella, Spodoptera litura and Maruca vitrata), Pod fly, Stem fly (Melanogromyza spp.), aphids, leafhoppers, brown plant hoppers, white backed plant hopper, thrips (Scritothrips dorsalis), whitefly, flies, bugs, and mites, red spider mites (Tetranychus urticae), chilli yellow mite, european red mite, diamond back moths , tobacco caterpillar (Spodoptera litura), semi looper, Green semi looper, Tea looper, soil pests as termites, grubs, mealy bugs and bollworms etc. apart from Lepidopteran species of pests.

[0198] In another embodiment of the present invention, the stable synergistic insecticidal composition of the present invention further comprises one or more agrochemically acceptable excipients including but not limited to the group comprising surfactant(s), dispersing agent(s), co-dispersant, anti-freezing agent(s), emulsifier(s)( (anionic and non-ionic), anti-foaming agentZdefoamer(s), wetting agent(s), antimicrobial / anti -bacterial agent(s), anti-caking agent , thickening agent / thickener(s), quick coating agent(s) or sticking agents / sticker(s), spreader(s), binder(s), pH-adjusting agent(s), anti-caking agent(s), adjuvant(s), filler(s) / suspension aid(s), colorant(s), carrier(s), buffering agent(s), polymer(s)rheology modifier(s), solvent(s), co-solvent(s) , biocide or a combination thereof. Additional components may also be included, e.g., protective colloids, carriers, adhesives, thixotropic agents, penetration agents, stabilisers, sequestering agents. More generally, the active materials can be combined with any solid or liquid carrier / additive, which complies with usual formulation techniques.

[0199] An adjuvant used in the present Invention is any material that is added to an agrochemical formulation to enhance or modify the performance of the formulation. An adjuvants used in the present invention to make it a safer to ecological environmental, having low toxicity and having no phytotoxicity effects on any part of the plant.

[0200] Examples of surfactant(s) and / or dispersing agent and / or co-dispersant used herein include but not limited polymeric anionic dispersant, polyarylphenyl ether phosphate, tristyryl phenol ethoxylate, Polymethyl methacrylate-polyethylene glycol graft copolymer, acrylate copolymer, acrylic copolymer, Ammonium Distyrylphenyl Ether Sulphate, polymeric dispersant, Calcium salt of alkyl benzene sulphonate, Non-ionic surfactant, polyalkoxylated butyl ether, acrylic graft copolymer, Sodium methyl oleoyl taurate , non-ionic proprietary surfactant, Methyl naphthalene sulfonic acid, polymer with formaldehyde, sodium salt, ethoxylated tristryl phenol Sulphate, alkyl naphthalene formaldehyde condensate .naphthalene sulfonic acid, phenol sulfonic acid-formaldehyde polycondensation as sodium salt, sodium salt condensate with formaldehyde, ethoxylated oleyl cetyl alcohol, Acrylate graft Copolymer, Anionic tristyrylphenol phosphate surfactant, Sodium Alkyl Naphthalene Sulfonate Blend, polyalkelene glycol ether, Sodium Isopropyl Naphthalene Sulfonate, Dialkyl naphthalene sulphonate sodium salt, Naphthalene Sulphonic Acid, Formaldehyde, Ethoxylated fatty glyceride , Ethoxylated Polyarylphenol Phosphate Ester, Lignosulfonic Acid, Sodium Salt, Sulfomethylated, ethoxylated fatty alcohol, methyl naphthalene sulfonic acid, polymer with formaldehyde sodium salt, Sodium polymethyl methacrylate, sodium polyacrylate, alkyl naphthalene sulfonate formaldehyde condensate or its sodium salt , Sodium Naphthalene Sulfonate formaldehyde condensate, Amine Salt of a Phosphated Tristyryl Phenol Ethoxylate, sodium lignosulfonate, calcium lignosulphonate, Sodium Alkyl Naphthalene Sulfonate, alkylphenol polyoxyethylene ether, sodium salt of naphthalene sulfonate condensate, alkyl naphthalene sulfonate condensate blend, polymeric surfactant, sodium salt of alkyl naphthalene sulfonate, sodium salt of methyl naphthalene sulfonate, polycarboxylate, naphthalene sulfonic acid-branched and linear derivative sodium salts, fatty alcohol polyoxyethylene ether, alcohol polyglycol ether, non-aqueous dispersant - non-ionic polymeric surfactant, aqueous dispersant - polymeric amphoteric aqueous dispersant or mixtures thereof and present in the range of 0.1-20% by weight of the composition.

[0201] Examples of wetting agent used herein include but not limited to tristyrylphenol ethoxylate non-ionic emulsifier, mixture of non-ionic surfactants, Blend of Anionic and Non-ionic, alkoxylated alcohol, block copolymer, alcohol polyglycol ether, alkyl olefin sulphates, dioctyl sulpho succinate, alkyl naphthalene sulphate , Di-isopropyl Napthalene sulphonate, Benzenesulfonic acid, Hydroxy polymer with formaldehyde, Phenol and Urea sodium salt, Polyalkoxy ethers, alkyl phenol ethoxylates, tri-styrenated phenol ethoxylate, EO / PO block co-polymers, butyl polyalkylene oxide block copolymer, sodium lauryl sulphate, sodium sulphates or mixtures thereof and present in the range of 0.1 -20% by weight of the total composition.

[0202] Examples of defoamer or antifoaming agent used herein include but not limited to silicon emulsion based anti-foam agents, Siloxane polyalkyleneoxide, Polydimethylsiloxane, trisiloxane ethoxylates, silicone oil, silicone compound, C10~C20 saturated fat acid compounds or C8~C10 aliphatic alcohols compound, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide polydimethylsiloxane emulsion and mixtures thereof and present in the range of 0.01-5.0 % by weight of the composition. Examples of anti-freezing agent used herein include but not limited to glycol, propylene glycol, mono ethylene glycol, glycerine, diethylene glycol, sorbitol, urea, mannitol, polyethylene glycol or mixtures thereof and present in the range of 1.0-20% by weight of the composition.

[0203] Examples of fillers used herein include but not limited to silicon dioxide, china-clay, kaolin, starch, bentonite, precipitated silica, fumed silica, lactose monohydrate, talcum powder, lactose, ammonium sulphate, water, sodium Sulphate, magnesium sulphate, sodium citrate, sodium chloride, potassium chloride and mixtures thereof and present in the range of 0.1-60 % by weight of the composition.

[0204] Examples of anti-caking agent used herein include but not limited to group of talc, hydrous magnesium silicate, magnesium carbonate, calcium carbonate, precipitate silica, silica powder, hydrophobic fumed silica and mixtures thereof and present in the range of 0.1-10% by weight of the composition.

[0205] Examples of carrier used herein include but not limited to silicon dioxide, china clay, kaolin, starch, bentonite, precipitated silica, silica powder, fumed silica, ppt silica powder, lactose monohydrate, talcum powder, lactose, ammonium sulpha or mixture thereof and present in the range of 0.1-45 % by weight of the composition.

[0206] Examples of biocide or anti-microbial agent used herein include but not limited to 1, 2,- Benzisothiazolin -3- one, blends of 1,2,- benzisothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, 5-chloro-2-methyl-4- isothiazolin-3-one, blends of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, zinc l-hydroxy-2(lH)-pyridinethione, blends of zinc l-hydroxy-2(lH)-pyridinethione and zinc oxide, and 2-n- octyl-4- isothiazolin-3-one or mixture thereof and present in the range of 0.01 to 10 % by weight of the composition.

[0207] Examples of rheology modifier or thickeners or thickening agents or suspending agents used herein include but not limited to polysaccharides, carboxymethyl cellulose, bentonite clay, aluminium magnesium silicate, hydroxy propyl cellulose, xanthan gum, gum arabic, Silica powder, gaur gum, carbomer, chitosan, precipitated silica or mixtures thereof and present in the range of 0.01-5.0 % by weight of the composition.

[0208] Examples of emulsifier(s) used herein include but not limited to araliphatic or aliphatic non-ionic oil emulsifier-ethoxylated sorbitol hexaester derived from oleic acid, emulsifier such as ethoxylated mono-, di- and trialkylphenols, ethoxylates of long -chain alcohols and polyethylene oxide / polypropylene oxide homo- and copolymers, Polymeric emulsifier (Nonionic polyalkylene oxide block copolymer), Ethoxylates of long- chain alkanols, Castor oil ethoxylate , ethoxylated monoalkylphenol, ethoxilates of cetyl alcohol and / or stearyl alcohol ; Tristyrylphenol ethoxylate-20 mole, Ethoxylated Tristyrylphenol ,and Anionic emulsifier such as alkali metal and ammonium salts of alkyl sulfates, of hemisulfates of ethoxylated alkanols and ethoxylated alkylphenols, alkylsulfonic acids, bis(phenylsulfonic acid) ethers and their alkali metal or ammonium salts, sodiumlaurylsulfate, sodium (cetyl / stearyl) sulfate or mixture thereof and present in the range of 0.01 -20 % by weight of the composition.

[0209] Examples of solvent(s) and co-solvent(s) used herein include but not limited to polar and non-polar solvent from the group comprising heavy aromatic hydrocarbon, N methyl pyrollidone (NMP), Solvent Naphtha (Solvent C-9), Di methyl sulfoxide (DMSO), Dimethylformamide (DMF), N- alcohol, 2-ethyl hexanol, alkyl amide, vegetable oil, mineral oil, distilled water, aromatic solvents, water or mixtures thereof and present in the range of 1.0 to 20% by weight of the composition.

[0210] Examples of colouring pigment(s) / dye(s) used herein include but not limited to red dye FGR03, Permanent Rubin L5-B-01, pigment blue 15:4, pigment blue 15:3, pigment blue 15:2, pigment blue 15:1 , pigment blue 80, pigment yellow 1 , pigment yellow 13, pigment red 112, pigment red 48:2, pigment red 48:1 , pigment red 57: 1 , pigment red 53:1 , pigment orange 43, pigment orange 34, pigment orange 5, pigment green 36, pigment green 7, pigment white 6, pigment brown 25, basic violet 10, basic violet 49, violet 23, acid red 51 , acid red 52, acid red 14, acid blue 9, acid yellow 23, basic red 10, basic red 108 or mixtures thereof and present in the range of 0.01- 10.0 % by weight of the composition.

[0211] Examples of polymer(s) used herein include but not limited to isocyanate, polyisocyanate used is toluene-2, 4-diisocyanate (TDI), diethylenetriamine (DETA), ethylene diamine (EDA), triethylenetetramine (TETA), and / or hexamethylene diamine (HMDA), diethanolglycine sodium salt, ethanoldiglycine disodium salt, hydroxymonocarboxylic acid compounds, hydroxydicarboxylic acid compounds, tetrasodium N,N- bis(carboxylatomethyl)-L-glutamate (GLDA), methylene diisocyanate (MDI), and / or low molecular weight polydiisocynates or mixtures thereof and present in the range of 0.01- 5.0 % by weight of the composition.

[0212] Examples of binder(s) used herein include but not limited to polyvinylpyrrolidone, polyvinyl alcohol, methyl cellulose, and carboxymethyl cellulose, polyisocyanate, polyterpene resin or mixtures thereof and present in the range of 0.01- 40 % by weight of the composition

[0213] Examples of preservative(s) used herein include but not limited to Methyl paraben (Methyl p- hydroxybenzoate), Propyl paraben (Propyl p-hydroxybenzoate), Methylisothiazolinone (MIT), Chloromethylisothiazolinone (CMIT), Benzisothiazolinone (BIT), DMDM Hydantoin, Imidazolidinyl Urea, Phenol, Cresol, Chlorocresol, Benzoic acid, Sorbic acid, Salicylic acid, Thymol (natural preservative), Sodium benzoate, Potassium sorbate, Bronopol (2-bromo-2-nitropropane-l,3-diol), Propyl para-hydroxy - benzoate or mixture thereof and present in the range of 0.01- 35 % by weight of the composition.

[0214] Examples of stabilizer(s) used herein include but not limited to butylated copolymer , Butylated Hydroxy Toluene (BHT), Butylated Hydroxyanisole (BHA), Ascorbic Acid (Vitamin C), Tocopherol (Vitamin E), Tinuvin® (e.g., Tinuvin 1130 - a benzotriazole UV absorber), Hindered Amine Light Stabilizers (HALS), Oxanilide derivatives, Ethoxylated Alkylphenols (e.g., nonylphenol ethoxylates), Block copolymers (e.g., Pluronic® types), Polyvinyl alcohol (PVA), Acrylic or Butylated Copolymers, Citric acid / Sodium citrate, Phosphates (e.g., Sodium or Potassium phosphate), Acetates (e.g., Sodium acetate), EDTA (Ethylenediaminetetraacetic acid), Citric acid (dual role: pH and chelation), NTA (Nitrilotriacetic acid), Xanthan gum, Attapulgite clay, Bentonite, Hydroxypropyl methylcellulose (HPMC) or mixture thereof and present in the range of 0.01- 35 % by weight of the composition.

[0215] Examples of pH adjusting agent(s) / buffering agent(s) used herein include but not limited to Citric Acid, Citric Acid Monohydrate, Citric Acid Dihydrate, Sodium Citrate, Potassium Citrate, Tartaric Acid, Potassium Hydrogen Tartrate, Lactic Acid, Sodium Phosphate (Monobasic or Dibasic), Potassium Phosphate (Monobasic / Dibasic), Sodium Bicarbonate, Sodium Carbonate, Ammonium Acetate / Ammonium Hydroxide, Acetic Acid, Sodium Acetate, Borax (Sodium Borate) or mixture thereof and present in the range of 0.01- 25 % by weight of the composition.

[0216] In yet another embodiment of the present invention, the stable synergistic insecticidal composition can be formulated as one or more of Capsule suspension (CS), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion for seed treatment (ES), Emulsion oil-in-water (EW), Flowable concentrate for seed treatment (FS), Granules (GR), Micro-emulsion (ME), Oil-dispersion (OD), Oil 20 miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Water soluble tablet (ST), Ultra-low volume (ULV) suspension, Tablet (TB), Ultra-low volume (ULV) liquid, Water dispersible granules (WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), a mixed formulation of CS and SC (ZC) or a mixed formulation of CS and SE (ZE) and a mixed formulation of CS and EW (ZW). In yet another embodiment of the present invention, the invention further provides the process for preparation of the said insecticidal composition, wherein the said composition can be one or more of Capsule suspension (CS), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion for seed treatment (ES), Emulsion oil-in-water (EW), Flowable concentrate for seed treatment (FS), Granules (GR), Micro-emulsion (ME), Oil-dispersion (OD), Oil miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo -emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Water soluble tablet (ST), Ultra-low volume (ULV) suspension, Tablet (TB), Ultra-low volume (ULV) liquid, Water dispersible granules (WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), a mixed formulation of CS and SC (ZC) or a mixed formulation of CS and SE (ZE) or a mixed formulation of CS and EW (ZW).

[0217] In further embodiment, depending on the formulation type, they comprise one or more liquid or solid carriers, appropriate surfactants (such as dispersants, protective colloids, emulsifiers, wetting agents and tackifiers), and appropriate further excipients which are customary for formulating agrochemical composition. Further excipients include e.g., organic and inorganic thickeners, bactericides, antifreeze agents, antifoams, colorants and, for seed formulations, adhesives.

[0218] In one embodiment, additives such as silwet power or silwet power super-wetter is an organosilicone based powder adjuvant that can enhance the water absorption efficiency of hard-to-wet soils by increasing their water infiltration, drainage, water retention and hydrophilicity; tallow amine ethoxylate increases the biocompatibility in environmental applications and help in the interactions of active ingredients; ammonium sulphate help is resistant to leaching and helps the crop to utilize nitrogen efficiently; urea clathrate provides superior wetting and spray retention properties and serves as an excellent nitrogen source for crops and epoxide soybean oil provides increased active ingredient uptake and improved rain fastness to the composition; and epoxide soybean oil provides increased active ingredient uptake and improved rain fastness to the composition. The said additives are stable and hygroscopic resulting in an efficient uptake and functioning.

[0219] In one embodiment, in agrochemical compositions, additives such as urea clathrate, Silwet Power or Silwet Power Super-wetter, tallow amine ethoxylate, ammonium sulphate, and epoxide soybean oil (ESO) serve distinct yet complementary functions, both individually and synergistically. Urea clathrate stabilizes volatile active ingredients by encapsulating them, thereby improving shelf life and enabling controlled release. Silwet Power or Silwet Power Super-wetter, which are trisiloxane-based superspreaders, reduce surface tension significantly and enhance the spreading, wetting, and penetration of the formulation on plant surfaces, improving bioavailability. Tallow amine ethoxylate, a non-ionic surfactant, aids in emulsification and acts as a strong adjuvant, enhancing the uptake of systemic active ingredients. Ammonium sulphate is used as a water conditioner to prevent antagonism from hard water ions like calcium and magnesium; it also enhances the absorption of certain insecticides. Epoxide soybean oil (ESO) contributes as a stabilizer and plasticizer, protecting active ingredients from UV and oxidative degradation while improving formulation compatibility.

[0220] In another embodiment, when used in combination in agrochemical composition, these additives enhance the overall efficacy, stability, and environmental safety of the agrochemical composition. For instance, the combined use of Silwet Power and ammonium sulphate can significantly boost pesticide performance, while ESO and urea clathrate together offer enhanced protection and sustained release of active ingredients. Thus, their synergistic interaction leads to improved performance and consistency under varying environmental and application conditions.In one embodiment, additives such as urea clathrate, silwet power or silwet power super-wetter, tallow amine ethoxylate, ammonium sulphate, and epoxide soybean oil either alone or in combination thereof, present in the range of 0.01 - 20% by weight of the composition.

[0221] In one embodiment, the composition according to the present invention acts synergistically to control insect pest in various crops. In another embodiment, the synergistic insecticidal composition of the present invention is found to be effective to control wide variety of insect pests.

[0222] Through the insecticidal composition of present invention, the number of applications to control wide range of pests appearing at the same time is minimised. The composition of present invention is highly safe to the user and to the environment. The composition offers the user a single homogenous application eliminating the need for tank mix. The composition also is cost-effective as it provides much greater simultaneous control and can be used in a variety of crops with a broader spectrum of protection.

[0223] The novel composition of the present invention has very advantageous, curative, preventive and systemic insecticidal properties for protecting plants and crops.

[0224] The composition of the present invention also provides control of insect-pests’ preventatively or curatively by applying an effective amount of the composition either pre-or post-infection.

[0225] Thus, before describing the present invention in detail, it is to be understood that this invention is not limited to particularly exemplified systems or process parameters that may of course, vary. It is also to be understood that the terminology used herein is for the purpose of describing particular embodiments of the invention only and is not intended to limit the scope of the invention in any manner. The use of examples anywhere in this specification including examples of any terms discussed herein is illustrative only, and in no way limits the scope and meaning of the invention or of any exemplified term. Likewise, the invention is not limited to various embodiments given in this specification. Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. In the case of conflict, the present document, including definitions will control.

[0226] In one embodiment, the composition according to the present invention acts synergistically to control pests in various crops. Representative examples of the present composition of this invention are provided below and are not to be construed as limiting in any manner:

[0227] EXAMPLES: GENERAL RECIPE OF COMPOSITION OF PRESENT INVENTION:

[0228] Example A: Novaluron 5.6% + Emamectin benzoate 1.4% + Indoxacarb 6.4% SC

[0229] MANUFACTURING PROCESS: Pre- mixing: 1. Charged D.M water into a clean reactor and stirred then added propylene glycol, Sodium Isopropyl Naphthalene Sulfonate, Ammonium Distyrylphenyl Ether Sulphate, Acrylate graft Copolymer, Polydimethyl siloxane, additives and l,2-Benzisothiazolin-3-one, further allowed it to mix well to make a homogeneous solution. 2. To the above solution further added Novaluron technical, Emamectin benzoate technical and Indoxacarb technical and mixed well to form a homogeneous slurry.

[0230] Wet-milling process:

[0231] 1. Allowed to pass the above prepared premix through bead mill at 400 to 500 Ltr / hr feed rate so as get a desired particle size. 2. The grinded material was collected in post mixer.

[0232] Post- Mixing:

[0233] 1. The milled slurry was collected into the post mixer and to Xantham gum solution was added.

[0234] 2. Mixed well till the slurry attains right viscosity

[0235] 3. Packed the formulation into HDPE bottles. STABILITY DATA: Novaluron 5.6% + Emamectin benzoate 1.4% + Indoxacarb 6.4% SC

[0236] Example B: Novaluron 5.6% + Emamectin benzoate 1.4% + Indoxacarb 6.4% WP

[0237] FORMULATION PROCESS: 1. Mixed all raw materials and technical & grinded in air jet mill.

[0238] 2. Checked the particle size after grinding, to make sure that it is less than 10 microns (D90).

[0239] 3. Post blended the grinded powder and mixed well.

[0240] STABILITY DATA: Novaluron 5.6% + Emamectin benzoate 1.4% + Indoxacarb 6.4% WP

[0241] Example C: Novaluron 5.6% + Emamectin benzoate 1.4% + Indoxacarb 6.4% OD

[0242] FORMULATION PROCESS: 1. Combined all components with stirring (-500 rpm) until homogeneous except Rheology modifier bentonite clay & ppt silica.

[0243] 2. Milled the formulation using a colloid bead mill (-3500 rpm) till the desired particle size is achieved (Preferred D90 <10pm).

[0244] 3. Removed the formulation from the colloid bead mill. 4. Added rheology modifier as Bentonite clay (Bentone SD-2) & Aerosil 200 proportionately.

[0245] STABILITY DATA: Novaluron 5.6% + Emamectin benzoate 1.4% + Indoxacarb 6.4% OD

[0246] Evaluation of synergistic effect of insecticidal composition of the present invention

[0247] A synergistic effect of two or more products exists whenever the action of an active ingredient combination is greater than the sum of the actions of the individual components. Synergism was calculated by using Colby’s method (Weeds, vol. 15 No. 1 (Jan 1967), pp. 20-2).

[0248] The synergistic action expected for a given combination of two active components can be calculated as follows:

[0249] The synergistic action expected for a given combination of three active components can be calculated as follows:

[0250] Where:

[0251] E represents expected percentage of insecticidal control for the combination of the two or three active ingredients at defined doses (for example equal to x, y and z, respectively). X is the percentage of insecticidal control observed by the compound (Novaluron) at a defined dose (equal to x).

[0252] Y is the percentage of insecticidal control observed by the compound (Emamectin benzoate) at a defined dose (equal to y).

[0253] Z is the percentage of insecticidal control observed by the compound (Indoxacarb) at a defined dose (equal to z).

[0254] When the percentage of insecticidal control observed for the combination is greater than the expected percentage, there is a synergism effect.

[0255] Ratio of O / E > 1, synergism observed

[0256] The present invention is illustrated by way of examples, the examples are meant for illustrative purposes and should not be construed as limiting.

[0257] Experiment for Synergistic activity of composition of the present invention:

[0258] Example 1- Details of experiment on cotton crop:

[0259] Field experiment for synergistic activity of Novaluron + Emamectin benzoate + Indoxacarb for the control of thrips and pink bollworm in cotton crop was conducted.

[0260] To evaluate the synergistic effect, cotton crop was sown in 5 m x 5 m plots maintaining 45 cm x 30 cm plant distance with three replications and in Randomized Block Design (RBD). The treatments were applied as foliar spray in the form of SC formulation @750 ml / ha. Each active component was applied twice in different ternary and binary compositions. Solo compositions were also taken for comparison. The treatment details are as under:

[0261] The treatments T1 to T28 were used as foliar application whereas no treatment was done for T29 control treatment. Two applications of each treatment were carried out at 15 -day intervals, initiated upon reaching the Economic Threshold Level (ETL) of the target insect population in the experimental plots. Observations on thrips (Thrips tabaci) were recorded before spraying and at 7 and 14 days after the first and second applications. For each of the 10 randomly selected cotton plants per plot, three leaves: one each from the upper, middle and lower canopy were examined to assess the thrips population. Observations for pink bollworm (Pectinophora gossypiella) were recorded before spraying and at 7 and 14 days after the first and second applications. On the same 10 randomly selected cotton plants per plot, 10 bolls per plant were examined to record per cent boll damage. The number of infested and healthy balls / fruits was counted and per cent ball damage was calculated accordingly. The per cent reduction in insect population was calculated over control. Based on the per cent reduction at 14 days after second spray in insect population the Expected control was calculated and compared with Observed control. The results of the trial have been presented here under in Table 1A. Table 1A: Synergistic effect of composition of the present invention (Novaluron + Emamectin benzoate

[0262] + Indoxacarb) against insect pest in cotton crop

[0263] It is clearly evident from the data presented in Table 1A on per cent insect pest control in cotton that the insecticidal composition comprising Novaluron + Emamectin benzoate + Indoxacarb (treatments T1 to T4) exhibits a synergistic effect against insect pests, as indicated by a Colby’s ratio greater than 1. The Colby’s ratio here reflects the combined efficacy against thrips and pink bollworm (PBW) in cotton. In contrast, the binary compositions involving any two of these insecticides i.e., Novaluron + Emamectin benzoate, Novaluron + Indoxacarb and Emamectin benzoate + Indoxacarb (treatments T5 to T16) were observed to be less effective, as no synergistic effect was observed for the control of both thrips and Pink bollworm (PBW) when compared to the composition of the present invention.

[0264] Experiment for Bio-efficacy evaluation of composition of the present invention:

[0265] For the ternary and binary composition, based on Novaluron + Emamectin benzoate + Indoxacarb evaluation under field conditions, the basic test composition as Novaluron 5.6% + Emamectin 1.4% + Indoxacarb 6.4% SC were manufactured

[0266] . For ternary composition, Novaluron 5.6% + Emamectin 1.4% + Indoxacarb 6.4% SC was used and for binary compositions, Novaluron 5.6% + Emamectin benzoate 1.4% SC, Novaluron 5.6% + Indoxacarb 6.4% SC and Emamectin benzoate 1.4% + Indoxacarb 6.4% SC were used. The solo formulations of Novaluron 5.6% SC, Emamectin benzoate 1.4% SC and Indoxacarb 6.4% SC were used for comparison. The other formulations namely Novaluron 8.8 w / w % SC, Emamectin benzoate 01.90 % EC and Indoxacarb 14.50 % SC available in the market were also used for comparison.

[0267] Example 2: Evaluation of the composition of the present invention on cotton

[0268] The stable synergistic insecticidal composition of the present invention Novaluron 5.6% + Emamectin benzoate 1.4% + Indoxacarb 6.4% SC was evaluated on cotton crop. The crop sowing was done in Randomized Block Design (RBD) with three replications maintaining a distance of 45 cm x 30 cm between plants and rows.

[0269] The observations were recorded for the following objectives.

[0270] Objectives:

[0271] 1. Bio-efficacy evaluation against thrips on cotton crop. 2. Bio-efficacy evaluation against pink bollworm on cotton crop.

[0272] 3. Bio-efficacy evaluation based on percent reduction in thrips population.

[0273] 4. Bio-efficacy evaluation based on percent reduction in pink bollworm population.

[0274] 5. Bio-efficacy evaluation based on cotton crop yield. 6. Phytotoxicity evaluation on cotton crop.

[0275] Treatment details:

[0276] Methodology:

[0277] The treatments T1 to T18 and T20 were used as foliar application whereas no treatment was done for T19 i.e., control treatment. All treatments were applied at the time of initiation of pest in the experimental plots. Observations on thrips (Thrips tabaci) were recorded before spraying and at 7 and 14 days after the first and second applications. For each of the 10 randomly selected cotton plants per plot, three leaves: one each from the upper, middle and lower canopy were examined to assess the thrips population. Observations for pink boll worm (Pectinophora gossypiella) were recorded before spraying and at 7 and 14 days after the first and 5 second applications. On the same 10 randomly selected cotton plants per plot, 10 bolls per plant were examined to record per cent boll damage. The number of infested and healthy bolls / fruits was counted and per cent bolls damage was calculated accordingly. The per cent reduction in insect population was calculated over control. The number of infested and healthy bolls was counted and per cent bolls damage was calculated accordingly. The per cent reduction in insect population was calculated over control. The crop yield was 0 recorded at crop harvest. The observations for phytotoxicity on cotton crop at 1, 3, 7, 10 and 14 days after 1stspray were also recorded. Results are presented in Table 2A, 2B, 2C, and 2D.

[0278] Table 2A: Field bio-efficacy evaluation of Novaluron 5.6% + Emamectin benzoate 1.4% + Indoxacarb 6.4% SC against thrips of cotton crop

[0279] Figures in parentheses are square root transformed values; NS= non-significant

[0280] Table 2B: Field bio-efficacy evaluation of Novaluron 5.6% + Emamectin benzoate 1.4% + Indoxacarb 6.4% SC against pink bollworm of cotton crop

[0281] Figures in parentheses are angular transformed values; NS= non-significant

[0282] Table 2C: Field bio-efficacy evaluation of Novaluron 5.6% + Emamectin benzoate 1.4% + Indoxacarb 6.4% SC based on cotton yield.

[0283] DAS - Days after crop sowing; q / ha: quintal per hectare

[0284] Table 2D: Phytotoxicity evaluation of Novaluron 5.6% + Emamectin benzoate 1.4% + Indoxacarb

[0285] 6.4% SC on cotton crop

[0286] From the example, it can be clearly seen that the stable synergistic insecticidal of the present invention is superior for controlling the thrips (Thrips tabaci) at 7 and 14 days after 1st& 2ndspray (Table 2A) and for controlling pink bollworm (Pectinophora gossypiella) population at 7 & 14 days after 1st& 2ndspray (Table 2B) in cotton crop as compared to the binary and solo composition applied at the same dosage and the other products such as Novaluron 8.8 w / w % SC, Emamectin benzoate 01.90 % EC and Indoxacarb 14.50 % SC available in the market. The yield of cotton crop also improved in the composition of the present invention Novaluron 5.6% + Emamectin benzoate 1.4% + Indoxacarb 6.4% SC as compared to binary and solo compositions (Table 2C).

[0287] The disclosed stable synergistic composition Novaluron 5.6% + Emamectin benzoate 1.4% + Indoxacarb 6.4% SC @ 562.5ml, 750 ml, 937.5ml and 1500 ml / ha further showed no phytotoxicity in the cotton crop even after 1, 3, 7, 10 and 14 days after 1stspray (Table 2D).

[0288] It is evident from the above data that the composition of the present invention i.e., Novaluron 5.6% + Emamectin benzoate 1.4% + Indoxacarb 6.4% SC resulted in good control of thrips and pink bollworm in cotton with higher respective yields as compared to the reference standard products (binary compositions and solo products). Further, the composition of present invention is resulted synergistic.

[0289] From the above investigations, it will be observed that numerous modifications and variations can be effectuated without departing from the true spirit and scope of the novel concepts of the present invention. It is to be understood that no limitations with respect to the specific embodiments illustrated is intended or should be inferred. It should be understood that all such modifications and improvements have been deleted herein for the sake of conciseness and readability but are properly within the scope of the following claims.

[0290] In particular, it has now been found, surprisingly that, for example, the insecticidal activity of the composition of present invention, compared with the insecticidal activity of individual components, is synergistic. In fact, various advantageous properties associated with the compositions according to the invention, include but are not limited to: knock down effect on insect pests including sucking pests complex at all developmental stages of insects such as egg, nymph, larva, pupa, and adult, preventing discoloration of leaves of plants and crops, enhanced tenderness to plants and crops, preventing ageing of plants and crops and other advantages familiar to a person skilled in the art.

[0291] From the above investigations, it will be observed that numerous modifications and variations can be effectuated without departing from the true spirit and scope of the novel concepts of the present invention. It is to be understood that no limitations with respect to the specific embodiments illustrated is intended or should be inferred. It should be understood that all such modifications and improvements have been deleted herein for the sake of conciseness and readability but are properly within the scope of the following claims.

Claims

I CLAIM

1. . A stable synergistic insecticidal composition comprising:A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives;B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives; andC) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives.

2. . The stable synergistic insecticidal composition as claimed in claim 1, comprising:A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition;B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1 -90% by weight of the composition; andC) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1 -90% by weight of the composition.

3. . A stable synergistic insecticidal composition comprising:A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives;B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives;C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives; andD) At least one or more additives.

4. . A stable synergistic insecticidal composition, as claimed in claimed in claim 3, comprising:A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives;B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives;C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives; andD) At least one or more additives selected from Urea clathrate, Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof.

5. . A stable synergistic insecticidal composition, as claimed in claimed in claim 4 and 5, comprising:A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition;B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1 -90% by weight of the composition;C) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-90% by weight of the composition; andD) At least one or more additives selected from Urea clathrate, Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof, in the range of 0.01-20% by weight of the composition.

6. . The stable synergistic insecticidal composition as claimed in claims 1-5, which further comprises one or more agrochemically acceptable excipients.

7. . The stable synergistic insecticidal composition as claimed in claim 6, wherein agrochemically acceptable excipients comprises surfactant(s), dispersing agent(s), co-dispersant, anti-freezing agent(s), emulsifier(s)( (anionic and non-ionic), anti-foaming agent / defoamer(s), wetting agent(s), biocide / antimicrobial / anti-bacterial agent(s), thickening agentZthickener(s), quick coating agent(s) or sticking agentsZsticker(s), spreader(s), binder(s), pH-adjusting agent(s), anti-caking agent(s), adjuvant(s), filler(s) / suspension aid(s), colorant(s) / colouring agent(s) / dye(s), carrier(s), stabilizer, buffering agent(s), polymer(s), safener(s), rheology modifier(s), solvent(s), co-solvent(s), or mixtures thereof.

8. . The stable synergistic insecticidal composition as claimed in claim 7, wherein the surfactant(s) and / or dispersing agent and / or co-dispersant is / are selected from the group comprising polymeric anionic dispersant, polyarylphenyl ether phosphate, tristyiyl phenol ethoxylate, Polymethyl methacrylatepolyethylene glycol graft copolymer, acrylate copolymer, acrylic copolymer, Ammonium Distyrylphenyl Ether Sulphate, polymeric dispersant, Calcium salt of alkyl benzene sulphonate, Non-ionic surfactant, polyalkoxylated butyl ether, acrylic graft copolymer, Sodium methyl oleoyl taurate , non-ionic proprietary surfactant, Methyl naphthalene sulfonic acid, polymer with formaldehyde, sodium salt, ethoxylated tristryl phenol Sulphate, alkyl naphthalene formaldehyde condensate , naphthalene sulfonic acid, phenol sulfonic acid-formaldehyde polycondensation as sodium salt, sodium salt condensate with formaldehyde, ethoxylated oleyl cetyl alcohol, Acrylate graft Copolymer, Anionic tri styrylphenol phosphate surfactant, Sodium Alkyl Naphthalene Sulfonate Condensate, polyalkelene glycol ether, Sodium Isopropyl Naphthalene Sulfonate, Dialkyl naphthalene sulphonate sodium salt, Naphthalene Sulphonic Acid, Formaldehyde, Ethoxylated fatty glyceride , Ethoxylated Polyarylphenol Phosphate Ester, Lignosulfonic Acid, Sodium Salt, Sulfomethylated, ethoxylated fatty alcohol, methyl naphthalene sulfonic acid, polymer with formaldehyde sodium salt, Sodium polymethyl methacrylate, sodium polyacrylate, alkyl naphthalene sulfonate formaldehyde condensate or its sodium salt , Sodium Naphthalene Sulfonate formaldehyde condensate, Amine Salt of a Phosphated Tristyryl Phenol Ethoxylate, sodium lignosulfonate, calcium lignosulphonate, Sodium Alkyl Naphthalene Sulfonate, alkylphenol polyoxyethylene ether, sodium salt of naphthalene sulfonate condensate, alkyl naphthalene sulfonate condensate blend, polymeric surfactant, sodium salt of alkyl naphthalene sulfonate, sodium salt of methyl naphthalene sulfonate, polycarboxylate, naphthalene sulfonic acid-branched and linear derivative sodium salts, fatty alcohol polyoxyethylene ether, alcohol polyglycol ether, non-aqueous dispersant - non- ionic polymeric surfactant, aqueous dispersant - polymeric amphoteric aqueous dispersant or mixtures thereof and present in the range of 0.1-20% by weight of the composition.

9. . The stable synergistic insecticidal composition as claimed in claim 7, wherein the wetting agent is / are selected form the group comprising tristyrylphenol ethoxylate non-ionic emulsifier, mixture of non- ionic surfactants, Blend of Anionic and Non-ionic, alkoxylated alcohol, block copolymer, alcohol polyglycol ether, alkyl olefin sulphates, dioctyl sulpho succinate, alkyl naphthalene sulphate , Di -isopropyl Napthalene sulphonate, Benzenesulfonic acid, Hydroxy polymer with formaldehyde, Phenol and Urea sodium salt, Polyalkoxy ethers, alkyl phenol ethoxylates, tri-styrenated phenol ethoxylate, EO / PO block co-polymers, butyl polyalkylene oxide block copolymer, sodium lauryl sulphate, sodium sulphates or mixtures thereof and present in the range of 0.1-20% by weight of the total composition.

10. . The stable synergistic insecticidal composition as claimed in claim 7, wherein the defoamer or antifoaming agent is / are selected from the group comprising silicon emulsion based anti-foam agents,Siloxane polyalkyleneoxide, Polydimethylsiloxane, trisiloxane ethoxylates, silicone oil, silicone compound, C10~C20 saturated fat acid compounds or C8~C10 aliphatic alcohols compound, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide polydimethylsiloxane emulsion and mixtures thereof and present in the range of 0.01-5.0 % by weight of the composition.

11. . The stable synergistic insecticidal composition as claimed in claim 7, wherein the anti-freezing agent is / are selected from the group comprising glycol, propylene glycol, mono ethylene glycol, glycerine, diethylene glycol, sorbitol, urea, mannitol, polyethylene glycol or mixtures thereof and present in the range of 1.0-20% by weight of the composition.

12. The stable synergistic insecticidal composition as claimed in claim 7, wherein the filler is / are selected from the group comprising silicon dioxide, china-clay, kaolin, starch, bentonite, precipitated silica, fumed silica, lactose monohydrate, talcum powder, lactose, ammonium sulphate, water, sodium Sulphate, magnesium sulphate, sodium citrate, sodium chloride, potassium chloride and mixtures thereof and present in the range of 0.1-60 % by weight of the composition.

13. The stable synergistic insecticidal composition as claimed in claim 7, wherein the anti-caking agent is / are selected from the group comprising of group of talc, hydrous magnesium silicate, magnesium carbonate, calcium carbonate, precipitate silica, silica powder, hydrophobic fumed silica and mixtures thereof and present in the range of 0.1-10% by weight of the composition.

14. The stable synergistic insecticidal composition as claimed in claim 7, wherein the carrier is / are selected from the group consisting of silicon dioxide, china clay, kaolin, starch, bentonite, precipitated silica, silica powder, fumed silica, lactose monohydrate, talcum powder, lactose, ammonium sulpha or mixture thereof and present in the range of 0.1-45 % by weight of the composition.

15. . The stable synergistic insecticidal composition as claimed in claim 7, wherein the biocide or anti-microbial agent(s) is / are selected from 1, 2,- Benzisothiazolin -3-one, blends of 1,2,- benzisothiazolin- 3-one and 2-methyl-4-isothiazolin-3-one, 5-chloro-2-methyl-4-isothiazolin-3-one, blends of 5-chloro-2- methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, zinc l-hydroxy-2(lH)-pyridinethione, blends of zinc l-hydroxy-2(lH)-pyridinethione and zinc oxide, and 2-n-octyl-4- isothiazolin-3-one or mixture thereof and present in the range of 0.01 to 10 % by weight of the composition.

16. . The stable synergistic insecticidal composition as claimed in claim 7, wherein the rheology modifier or thickeners or thickening agents or suspending agent(s) is / are selected from polysaccharides, carboxymethyl cellulose, bentonite clay, aluminium magnesium silicate, hydroxy propyl cellulose, xanthan gum, gum arabic, Silica powder, gaur gum, carbomer, chitosan, precipitated silica or mixtures thereof and present in the range of 0.01-5.0 % by weight of the composition.

17. . The stable synergistic insecticidal composition as claimed in claim 7, wherein the emulsifier(s) is / are selected from group consisting of araliphatic or aliphatic non-ionic oil emulsifier-ethoxylated sorbitol hexaester derived from oleic acid, emulsifier such as ethoxylated mono-, di- and trialkylphenols, ethoxylates of long-chain alcohols and polyethylene oxide / polypropylene oxide homo- and copolymers, Polymeric emulsifier (Nonionic polyalkylene oxide block copolymer), Ethoxylates of long-chain alkanols, Castor oil ethoxylate , ethoxylated mono alkylphenol, ethoxilates of cetyl alcohol and / or stearyl alcohol ; Tri styrylphenol ethoxylate-20 mole, Ethoxylated Tristyrylphenol ,and Anionic emulsifier such as alkali metal and ammonium salts of alkyl sulfates, of hemisulfates of ethoxylated alkanols and ethoxylated alkylphenols, alkylsulfonic acids, bis(phenylsulfonic acid) ethers and their alkali metal or ammonium salts, sodiumlaurylsulfate, sodium (cetyl / stearyl) sulfate or mixture thereof and present in the range of 0.01 -20 % by weight of the composition.

18. . The stable synergistic insecticidal composition as claimed in claim 7, wherein the solvent(s) and co-solvent are selected from polar and non-polar solvent from the group comprising heavy aromatic hydrocarbon, diethyl phthalate, N methyl pyrollidone (NMP) , Solvent Naphtha (Solvent C-9), Di methyl sulfoxide (DMSO), Dimethylformamide (DMF), N- alcohol, 2-ethyl hexanol , alkyl amide, vegetable oil, mineral oil, distilled water, aromatic solvents, water or mixtures thereof and present in the range of 1.0 to 20% by weight of the composition.

19. . The stable synergistic insecticidal composition as claimed in Claim 7, wherein the colouring pigment(s) / dye(s) are selected from red dye FGR03, Permanent Rubin L5-B-01, pigment blue 15:4, pigment blue 15:3, pigment blue 15:2, pigment blue 15:1 , pigment blue 80, pigment yellow 1 , pigment yellow 13, pigment red 112, pigment red 48:2, pigment red 48:1 , pigment red 57: 1 , pigment red 53:1 , pigment orange 43, pigment orange 34, pigment orange 5, pigment green 36, pigment green 7, pigment white 6, pigment brown 25, basic violet 10, basic violet 49, violet 23, acid red 51 , acid red 52, acid red 14, acid blue 9, acid yellow 23, basic red 10, basic red 108 or mixtures thereof and present in the range of 0.01- 10.0 % by weight of the composition.

20. . The stable synergistic insecticidal composition as claimed in claim 7, wherein the polymer(s) is / are selected from isocyanate, polyisocyanate used is toluene-2, 4-diisocyanate (TDI), diethylenetriamine(DETA), ethylene diamine (EDA), triethylenetetramine (TETA), and / or hexamethylene diamine (HMD A), diethanolglycine sodium salt, ethanoldiglycine disodium salt, hydroxymonocarboxylic acid compounds, hydroxydicarboxylic acid compounds, tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate (GLDA), methylene diisocyanate (MDI), and / or low molecular weight polydiisocynates or mixtures thereof and present in the range of 0.01- 5.0 % by weight of the composition.

21. . The stable synergistic insecticidal composition as claimed in claim 7, wherein the bidner(s) is / are selected from polyvinylpyrrolidone (PVP), polyvinyl alcohol, methyl cellulose, and carboxymethyl cellulose, polyisocyanate, polyterpene resin or mixtures thereof and present in the range of 0.01- 40 % by weight of the composition

22. . The stable synergistic insecticidal composition as claimed in claim 7, wherein the preservative(s) is / are selected from Methyl paraben (Methyl p -hydroxybenzoate), Propyl paraben (Propyl p- hydroxybenzoate), Methylisothiazolinone (MIT), Chloromethylisothiazolinone (CMIT), Benzisothiazolinone (BIT), DMDM Hydantoin, Imidazolidinyl Urea, Phenol, Cresol, Chlorocresol, Benzoic acid, Sorbic acid, Salicylic acid, Thymol (natural preservative), Sodium benzoate, Potassium sorbate, Bro nopol (2-bromo-2 -nitropropane- 1,3-diol), Propyl para-hydroxy-benzoate or mixture thereof and present in the range of 0.01- 35 % by weight of the composition.

23. . The stable synergistic insecticidal composition as claimed in claim 7, wherein the stabilizer(s) is / are selected from butylated copolymer , Butylated Hydroxy Toluene (BHT), Butylated Hydroxyanisole (BHA), Ascorbic Acid (Vitamin C), Tocopherol (Vitamin E), Tinuvin® (e.g., Tinuvin 1130 - a benzotriazole UV absorber), Hindered Amine Light Stabilizers (HALS), Oxanilide derivatives, Ethoxylated Alkylphenols (e.g., nonylphenol ethoxylates), Block copolymers (e.g., Pluronic® types), Polyvinyl alcohol (PVA), Acrylic or Butylated Copolymers, Citric acid / Sodium citrate, Phosphates (e.g., Sodium or Potassium phosphate), Acetates (e.g., Sodium acetate), EDTA (Ethylenediaminetetraacetic acid), Citric acid (dual role: pH and chelation), NTA (Nitrilotriacetic acid), Xanthan gum, Attapulgite clay, Bentonite, Hydroxypropyl methylcellulose (HPMC) or mixture thereof and present in the range of 0.01- 35 % by weight of the composition.

24. . The stable synergistic insecticidal composition as claimed in claim 7, wherein the pH adjusting agent(s) / buffering agent(s) is / are selected from Citric Acid, Citric Acid Monohydrate, Citric Acid Dihydrate, Sodium Citrate, Potassium Citrate, Tartaric Acid, Potassium Hydrogen Tartrate, Lactic Acid, Sodium Phosphate (Monobasic or Dibasic), Potassium Phosphate (Monobasic / Dibasic), Sodium Bicarbonate, Sodium Carbonate, Ammonium Acetate / Ammonium Hydroxide, Acetic Acid, Sodium Acetate, Borax (Sodium Borate) or mixture thereof and present in the range of 0.01- 25 % by weight of the composition.

25. . The stable synergistic insecticidal composition as claimed in any one of the claims 1 to 24, wherein the composition is in form of Emulsifiable concentrate (EC), Capsule suspension (CS), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion for seed treatment (ES), Emulsion oil-in- water (EW), Flowable concentrate for seed treatment (FS), Granules (GR Micro-emulsion concentrate (MEC), Oil-dispersion (OD), Oil miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Water soluble tablet (ST), Ultra-low volume (ULV) suspension, Tablet (TB), Ultra-low volume (ULV) liquid, Water dispersible granules (WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), a mixed composition of CS and SC (ZC) or a mixed composition of CS and SE (ZE) and a mixed composition of CS and EW (ZW).

26. . The stable synergistic insecticidal composition as claimed in claims 1 to 25, wherein the use of said composition promotes plant health, growth and increases plant yield in the field.

27. A kit-of-parts comprising a plurality of components, wherein said plurality of components comprises:A) At least one benzoylurea insecticide selected from Novaluron, Chlorfluazuron, Diflubenzuron, Flufenoxuron, Lufenuron or its agrochemically acceptable salts, esters or its derivatives;B) At least one avermectin insecticide selected from Emamectin, Emamectin benzoate, Abamectin or its agrochemically acceptable salts, esters or its derivatives; andC) Indoxacarb or its agrochemically acceptable salts, esters or its derivatives.

28. . A process for preparing a stable synergistic insecticidal composition as claimed in claims 1-25.

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