Automatically regulatable low-temperature storage device

By employing a Stirling refrigeration mechanism in cryogenic storage equipment to achieve the cyclic liquefaction of liquid nitrogen, the problems of robotic arm damage and the inability to recycle liquid nitrogen are solved, thereby improving the reliability and energy efficiency of cryogenic storage equipment.

WO2026025813A1PCT designated stage Publication Date: 2026-02-05SHANGHAI ORIGINCELL BIOLOGICAL CRYO EQUIP CO LTD
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Patent Information

Application Number
PCT/CN2025/070483
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-07-29
Filing Date
2025-01-03
Publication Date
2026-02-05

AI Technical Summary

Technical Problem

In existing cryogenic storage equipment, robotic arms are prone to damage due to prolonged exposure to ultra-low temperatures. Liquid nitrogen cannot be recycled and cannot provide cooling in the event of a power outage, resulting in high costs and low reliability.

Method used

Design an automatic adjustable cryogenic storage device. By setting the operating area outside the storage chamber, a Stirling refrigeration mechanism is used to achieve the cyclic liquefaction of liquid nitrogen, avoiding long-term exposure of the robotic arm to the cryogenic environment, and maintaining the refrigeration function even in the event of a power outage.

Benefits of technology

It reduces the cost of using liquid nitrogen, improves the reliability and energy efficiency of the equipment, and enables automatic adjustable temperature control of samples within the range of +5℃ to -200℃.

✦ Generated by Eureka AI based on patent content.

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Abstract

Disclosed in the present invention is an automatically regulatable low-temperature storage device, comprising a sample storage cabin, a rotary storage mechanism and a refrigeration cycle mechanism, wherein the sample storage cabin is internally provided with a rotatable rotary storage mechanism, the sample storage cabin is provided with the refrigeration cycle mechanism, the refrigeration cycle mechanism may perform cyclic refrigeration on the sample storage cabin, and the rotary storage mechanism may store a sample. The beneficial effects of the present invention include that vaporized nitrogen can be converted into liquid nitrogen by means of a refrigeration cycle mechanism, so as to recycle the liquid nitrogen, thereby reducing the consumption of the liquid nitrogen; moreover, the apparatus can be used for both hydraulic and electric purposes and can achieve automatic regulation of the temperature of a sample storage cabin, and the apparatus is conveniently disassembled and replaced, is energy-saving and environmentally friendly, and is easily cleaned.
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Description

An automatically adjustable low-temperature storage device TECHNICAL FIELD

[0001] The present application relates to the technical field of sample storage, in particular to an automatically adjustable low-temperature storage device. BACKGROUND

[0002] In the field of biological sample storage, low-temperature access equipment is used to store biological samples such as blood samples, vaccines, and virus seeds at low temperatures, so that the samples can be stored in an active state at low temperatures.

[0003] The application number is CN202110990457.1, the application date is August 26, 2021, and the application is a rotating cage type ultra-low temperature biological sample automatic access system. The sample storage method is a rotating drum type, but the sample access process is to set a mechanical arm at the center axis position of the storage area to perform tube picking operation. However, since the storage area is an ultra-low temperature environment, the electrical elements of the mechanical arm are easily damaged in the ultra-low temperature environment for a long time, which affects the sample access. Moreover, the current use of liquid nitrogen is relatively high in cost and cannot be recycled. In the case of power failure, refrigeration cannot be performed. Therefore, the inventor designs an automatically adjustable low-temperature storage device. SUMMARY

[0004] The purpose of this section is to summarize some aspects of the embodiments of the present application and briefly introduce some preferred embodiments. Some simplifications or omissions may be made in this section and the abstract and title of the specification to avoid obscuring the purpose of this section, the abstract and the title. Such simplifications or omissions cannot be used to limit the scope of the present application.

[0005] In view of the above or the problems existing in the prior art, the present application is proposed.

[0006] Therefore, the purpose of the present application is to provide an automatically adjustable low-temperature storage device, which can avoid the long-term operation of the mechanical arm in the low-temperature environment by setting the operation area outside the storage cabin and setting the scooping device in the operation area. By using the Stirling refrigeration mechanism, the liquid nitrogen can be recycled and liquefied, avoiding the waste of liquid nitrogen and greatly reducing the use cost of liquid nitrogen.

[0007] To solve the above technical problems, the present application provides the following technical scheme: an automatically adjustable low-temperature storage device, comprising a sample storage cabin, a rotating storage mechanism, and a refrigeration circulation mechanism; the sample storage cabin is provided with a rotatable rotating storage mechanism, and the sample storage cabin is provided with a refrigeration circulation mechanism; the refrigeration circulation mechanism can circulate refrigeration for the sample storage cabin, and the rotating storage mechanism can store samples.

[0008] As a preferred scheme of the automatic adjustable low-temperature storage device, the refrigeration cycle mechanism comprises a cooling cabin and a refrigeration machine; the cooling cabin is arranged inside the sample storage cabin and inside the rotating storage mechanism; the refrigeration machine is arranged above the sample storage cabin; the upper end of the cooling cabin is communicated with the refrigeration machine; the refrigeration machine can receive the nitrogen gas vaporized in the cooling cabin and liquefy the nitrogen gas and return the nitrogen gas into the cooling cabin.

[0009] As a preferred scheme of the automatic adjustable low-temperature storage device, the cooling cabin is a liquid nitrogen tank and is fixedly arranged in the sample storage cabin; the liquid nitrogen tank is internally provided with a liquid adding system.

[0010] As a preferred scheme of the automatic adjustable low-temperature storage device, the refrigeration machine comprises a refrigeration module, a first pipeline and a second pipeline; the upper ends of the first pipeline and the second pipeline are connected with the refrigeration module; the lower end of the first pipeline is arranged at an upper position of the cooling cabin; and the lower end of the second pipeline is arranged at a lower position of the cooling cabin.

[0011] As a preferred scheme of the automatic adjustable low-temperature storage device, the upper end of the cooling cabin is further provided with a control mechanism; and the control mechanism can refrigerate the cooling cabin.

[0012] As a preferred scheme of the automatic adjustable low-temperature storage device, the upper end of the cooling cabin is further provided with a pressure relief assembly; and the pressure relief assembly can relieve the pressure and exhaust the gas in the cooling cabin.

[0013] As a preferred scheme of the automatic adjustable low-temperature storage device, the rotating storage mechanism can drive the cooling cabin to rotate; the extended end of the refrigeration machine is arranged inside the cooling cabin; the cooling cabin is internally provided with a cooling liquid; the cooling cabin is a central rotating shaft and is communicated with the refrigeration cycle mechanism at the upper end.

[0014] As a preferred scheme of the automatic adjustable low-temperature storage device, the rotating storage mechanism can drive the cooling cabin to rotate; the cooling cabin is a central rotating shaft integrated structure; and the cooling cabin is internally provided with liquid nitrogen.

[0015] As a preferred scheme of the automatic adjustable low-temperature storage device, the rotating storage mechanism comprises a driving member and a rotating storage assembly; the driving member is arranged on the upper end of the sample storage cabin; the rotating storage assembly is arranged inside the sample storage cabin; the driving member can drive the rotating storage assembly to rotate; and the rotating storage assembly can store the baskets.

[0016] As a preferred scheme of the automatic adjustable low-temperature storage device, the rotating storage assembly comprises vertical storage frames; a plurality of groups of the vertical storage frames are circumferentially arranged into a storage disc; the upper end of the storage disc is provided with a gear disc; and the driving member can drive the gear disc to rotate.

[0017] As a preferred scheme of the automatic adjustable low-temperature storage device, the upper end of the sample storage cabin is provided with a driving member, the upper end of the cooling cabin is provided with a gear disc, the gear disc is arranged on one side of the driving member, the driving member can drive the gear disc and the cooling cabin to rotate, and the inside of the sample storage cabin is provided with a rotating storage assembly, and the cooling cabin can drive the rotating storage assembly to rotate.

[0018] As a preferred scheme of the automatic adjustable low-temperature storage device, the rotating storage assembly comprises vertical storage frames, a plurality of groups of vertical storage frames are circumferentially arranged into a storage disc, the upper end of the storage disc is provided with a rotating disc, the rotating disc is connected with the cooling cabin, and the cooling cabin can drive the rotating disc and the storage disc to rotate.

[0019] As a preferred scheme of the automatic adjustable low-temperature storage device, the upper end of the sample storage cabin is provided with a vertical channel mechanism, and the sample in the rotating storage mechanism can be accessed through the vertical channel mechanism.

[0020] As a preferred scheme of the automatic adjustable low-temperature storage device, the vertical channel mechanism comprises a vertical channel, a channel door driving member, a transmission member and a channel door, the vertical channel is formed in the sample storage cabin, the channel door is arranged in the vertical channel, the channel door is connected with the channel door driving member at the upper end through the transmission member, and the channel door driving member drives the channel door to open and close the vertical channel through the transmission member.

[0021] As a preferred scheme of the automatic adjustable low-temperature storage device, the control box is arranged on the side of the sample storage cabin, and the control box can control the inside of the sample storage cabin to be temperature-adjusted.

[0022] As a preferred scheme of the automatic adjustable low-temperature storage device, the control box is arranged on the side of the sample storage cabin, and the control box can control the inside of the sample storage cabin to be temperature-adjusted.

[0023] The application has the advantages that the refrigeration circulation mechanism can convert the vaporized nitrogen into liquid nitrogen, so that the liquid nitrogen can be recycled, thereby reducing the consumption of liquid nitrogen; the device can be used in liquid and electricity modes, the temperature of the sample storage cabin can be automatically adjusted, the device is convenient to disassemble and replace, energy-saving and environment-friendly, and easy to clean. BRIEF DESCRIPTION OF DRAWINGS

[0024] In order to more clearly illustrate the technical solutions of the embodiments of the application, the drawings needed in the embodiment description will be briefly introduced. Obviously, the drawings in the following description are only some embodiments of the application, and other drawings can be obtained by those skilled in the art without creative labor. Among them:

[0025] Fig. 1 is a schematic diagram of the overall structure of embodiment 1 of the automatic adjustable low-temperature storage device.

[0026] Fig. 2 is a schematic diagram of the internal structure of embodiment 1 of the automatic adjustable low-temperature storage device.

[0027] Fig. 3 is a schematic diagram of the internal cross-section of embodiment 1 of the automatic adjustable low-temperature storage device.

[0028] Fig. 4 is a schematic diagram of the rotating storage mechanism of embodiment 1 of the automatic adjustable low-temperature storage device.

[0029] Fig. 5 is an enlarged view of the partial refrigeration machine of embodiment 1 of the automatic adjustable low-temperature storage device.

[0030] Fig. 6 is a schematic diagram of the overall half-section of embodiment 1 of the automatic adjustable low-temperature storage device.

[0031] Fig. 7 is a schematic diagram of the vertical passage mechanism of the automatic adjustable low-temperature storage device.

[0032] Fig. 8 is a schematic diagram of embodiment 2 of the automatic adjustable low-temperature storage device.

[0033] Fig. 9 is a schematic diagram of embodiment 3 of the automatic adjustable low-temperature storage device.

[0034] Fig. 10 is a schematic diagram of the overall half-section of embodiment 3 of the automatic adjustable low-temperature storage device.

[0035] Reference signs: sample storage cabin, 1; rotating storage mechanism, 2; refrigeration cycle mechanism, 3; cooling cabin, 31; refrigeration machine, 32; refrigeration module, 321; first pipe, 322; second pipe, 323; control mechanism, 4; pressure relief assembly, 5; driving member, 21; rotating storage assembly, 22; vertical storage frame, 221; storage disc, 222; gear disc, 223; rotating disc, 225; vertical passage mechanism, 6; passage door driving member, 61; transmission member, 62; passage door, 63; control box, 7; power distribution system, 71; condenser, 72; control member, 73; DETAILED DESCRIPTION

[0036] In order to make the above-mentioned objectives, features and advantages of the present application more apparent and easy to understand, the specific embodiments of the present application will be described in detail below with reference to the accompanying drawings.

[0037] In the following description, many specific details are set forth in order to provide a thorough understanding of the present application, but the present application can also be practiced in other ways different from those described herein, and those skilled in the art can make similar extensions without departing from the spirit of the present application, so the present application is not limited to the specific embodiments disclosed below.

[0038] Secondly, the "one embodiment" or "embodiment" referred to herein is intended to mean a specific feature, structure, or characteristic under at least one implementation of the application. The various appearances of "in one embodiment" or "in an embodiment" in the specification are not all referring to the same embodiment, nor are they mutually exclusive, although they can sometimes refer to the same embodiment. Embodiment 1

[0039] Referring to FIGS. 1-7, a first embodiment of the application provides an automatically adjustable low-temperature storage device, which includes a sample storage cabin 1, a rotating storage mechanism 2, and a refrigeration cycle mechanism 3. The rotating storage mechanism 2 is arranged in the sample storage cabin 1, and can rotate in the sample storage cabin 1 and store a basket, which stores samples. The refrigeration cycle mechanism 3 can refrigerate the sample storage cabin 1.

[0040] Specifically, the sample storage cabin 1, the rotating storage mechanism 2, and the refrigeration cycle mechanism 3; the sample storage cabin 1 is provided with the rotatable rotating storage mechanism 2, and the sample storage cabin 1 is provided with the refrigeration cycle mechanism 3, which can cyclically refrigerate the sample storage cabin 1, and the rotating storage mechanism 2 can store samples.

[0041] Preferably, the refrigeration cycle mechanism 3 is a Stirling refrigeration.

[0042] Preferably, the refrigeration cycle mechanism 3 can cyclically refrigerate the sample storage cabin 1, so that even in the case of power failure, the sample storage cabin 1 can be refrigerated, avoiding damage to the samples caused by power failure.

[0043] Further, the refrigeration cycle mechanism 3 includes a cooling cabin 31 and a refrigerator 32; the cooling cabin 31 is arranged inside the sample storage cabin 1 and inside the rotating storage mechanism 2, and the refrigerator 32 is arranged above the sample storage cabin 1. The upper end of the cooling cabin 31 is in communication with the refrigerator 32, the refrigerator 32 can receive the nitrogen gas vaporized in the cooling cabin 31, and liquefy the nitrogen gas and return it to the cooling cabin 31.

[0044] Further, the cooling cabin 31 is a liquid nitrogen tank, which is fixedly arranged in the sample storage cabin 1, and the liquid nitrogen tank is provided with a liquid adding system.

[0045] Preferably, the liquid adding system can be used to initially add liquid to the cooling cabin 31.

[0046] Preferably, a certain amount of liquid nitrogen is arranged in the liquid nitrogen tank, and there is no need to add liquid during the process.

[0047] Preferably, the cooling cabin 31 is arranged at the middle position of the rotating storage mechanism 2, which can facilitate low-temperature refrigeration of the sample boxes and sample tubes on the rotating storage mechanism 2.

[0048] Preferably, the liquid nitrogen in the cooling cabin 31 is naturally vaporized, and the vaporized nitrogen gas enters the upper end, the refrigerator 32 liquefies the vaporized nitrogen gas and flows into the bottom end of the cooling cabin 31 again, so as to perform the circulating refrigeration, and the circulating refrigeration can be performed even in the case of power failure.

[0049] Further, the refrigerator 32 comprises a refrigeration module 321, a first pipeline 322, and a second pipeline 323; the upper ends of the first pipeline 322 and the second pipeline 323 are connected with the refrigeration module 321, the lower end of the first pipeline 322 is arranged at the upper position of the cooling cabin 31, and the lower end of the second pipeline 323 is arranged at the lower position of the cooling cabin 31.

[0050] Preferably, the nitrogen gas can be sucked into the refrigeration module 321 through the first pipeline 322 to be cooled and liquefied, the liquefied liquid nitrogen can be sent to the bottom of the cooling cabin 31 through the second pipeline 323, and the vaporization is performed again from the bottom to the top, so as to freeze the low-temperature sample storage mechanism 2, and the circulating cooling of the vaporized nitrogen gas is performed, thereby realizing the circulating refrigeration through the liquid nitrogen and the nitrogen gas.

[0051] Preferably, the liquid nitrogen can realize zero loss, and the automatic adjustable temperature technology of +5℃ to -200℃ can be realized.

[0052] Preferably, in the embodiment, the refrigerant medium is not needed, the environmental protection can be effectively performed, and the device can save 50% energy than the existing refrigerator.

[0053] Further, the control mechanism 4 is further arranged above the sample storage cabin 1, and the control mechanism 4 can refrigerate the cooling cabin 31.

[0054] Preferably, the control mechanism 4 can adopt the solar energy or the mobile power supply and the like, and the sample in the sample storage cabin 1 can be effectively prevented from being damaged in the case of power failure.

[0055] Further, the pressure relief assembly 5 is further arranged on the cooling cabin 31, and the pressure relief assembly 5 can perform the pressure relief and exhaust of the cooling cabin 31.

[0056] Preferably, the pressure relief assembly 5 can perform the exhaust when the liquid nitrogen is first added, and the exhaust can be actively performed when the internal pressure is large.

[0057] Further, the rotating storage mechanism 2 comprises a driving piece 21 and a rotating storage assembly 22; the driving piece 21 is arranged on the sample storage cabin 1, and the rotating storage assembly 22 is arranged in the sample storage cabin 1; the driving piece 21 can drive the rotating storage assembly 22 to rotate, and the rotating storage assembly 22 can store the basket, and the sample box can be stored on the basket.

[0058] Preferably, the driving member 21 comprises a motor and a gear transmission shaft, the motor drives the gear transmission shaft to rotate, the gear transmission shaft is in meshing connection with the gear disc 223, so as to drive the gear disc 223 to rotate, that is, to drive the storage disc 222 to rotate.

[0059] Further, the rotating storage assembly 22 comprises vertical storage frames 221, a plurality of groups of vertical storage frames 221 are circumferentially arranged into the storage disc 222, the upper end of the storage disc 222 is provided with the gear disc 223, and the driving member 21 can drive the gear disc 223 to rotate.

[0060] Preferably, the vertical storage frame 221 is a basket, and can store sample boxes.

[0061] Further, the sample storage cabin 1 is provided with a vertical channel mechanism 6, and the sample in the rotating storage mechanism 2 can be accessed through the vertical channel mechanism 6.

[0062] Preferably, the vertical channel mechanism 6 can be opened or closed, in the opened state, the sample box on the vertical storage frame 221 can be scooped up through an external scooping mechanism, and in the closed state, the external scooping mechanism cannot enter the inside of the sample storage cabin 1, so as to avoid that the ultra-low temperature environment in the inside of the sample storage cabin 1 damages components of the external scooping mechanism and the picking mechanism.

[0063] Further, the vertical channel mechanism 6 comprises a vertical channel, a channel door driving member 61, a transmission member 62 and a channel door 63, the vertical channel is formed in the sample storage cabin 1, the channel door 63 is arranged in the vertical channel, the channel door 63 is connected with the upper end channel door driving member 61 through the transmission member 62, and the channel door driving member 61 drives the channel door 63 to open or close the vertical channel through the transmission member 62.

[0064] Further, the vertical channel mechanism 6 comprises a vertical channel, a channel door driving member 61, a transmission member 62 and a channel door 63, the vertical channel is formed in the sample storage cabin 1, the channel door 63 is arranged in the vertical channel, the channel door 63 is connected with the upper end channel door driving member 61 through the transmission member 62, and the channel door driving member 61 drives the channel door 63 to open or close the vertical channel through the transmission member 62.

[0065] Further, the control box 7 is arranged on the side of the sample storage cabin 1, and the control box 7 can control the temperature in the inside of the sample storage cabin 1.

[0066] In summary, the multifunctional ultra-low temperature refrigerator with liquid and electricity dual functions has better sample cold storage effect, the liquid nitrogen can be supplemented to realize long-term use, the use cost of the liquid nitrogen is reduced, the temperature can be automatically adjusted from +5 DEG C to -200 DEG C, no refrigerant medium is needed, the refrigerator is more energy-saving and environment-friendly, and the use cost is reduced. Embodiment 2

[0067] Referring to Figure 8, for the second embodiment of the present application, based on the first embodiment, the automatically adjustable low-temperature storage device comprises a sample storage cabin 1, a rotating storage mechanism 2, and a refrigeration circulation mechanism 3. The rotating storage mechanism 2 is arranged in the sample storage cabin 1, and the rotating storage mechanism 2 can rotate in the sample storage cabin 1 and store a basket, and the basket stores samples. The refrigeration circulation mechanism 3 can refrigerate the sample storage cabin 1.

[0068] Specifically, the sample storage cabin 1, the rotating storage mechanism 2, and the refrigeration circulation mechanism 3; the sample storage cabin 1 is provided with the rotatable rotating storage mechanism 2, and the sample storage cabin 1 is provided with the refrigeration circulation mechanism 3, which can circulate refrigeration for the sample storage cabin 1, and the rotating storage mechanism 2 can store samples.

[0069] Preferably, the refrigeration circulation mechanism 3 can circulate refrigeration for the sample storage cabin 1, so that even in the case of power failure, the sample storage cabin 1 can be refrigerated, avoiding damage to the samples caused by power failure.

[0070] Preferably, the refrigeration circulation mechanism 3 is a Stirling refrigeration.

[0071] Further, the refrigeration circulation mechanism 3 comprises a cooling cabin 31 and a refrigerator 32; the cooling cabin 31 is arranged inside the sample storage cabin 1 and inside the rotating storage mechanism 2, and the refrigerator 32 is arranged above the sample storage cabin 1. The upper end of the cooling cabin 31 is in communication with the refrigerator 32, and the refrigerator 32 can receive the nitrogen gas vaporized in the cooling cabin 31 and liquefy the nitrogen gas and return it to the cooling cabin 31.

[0072] Preferably, the liquid nitrogen in the cooling cabin 31 will be naturally vaporized, and the vaporized nitrogen gas will enter the upper end. The refrigerator 32 will liquefy the vaporized nitrogen gas and flow into the bottom end of the cooling cabin 31 again, so as to circulate refrigeration, even in the case of power failure.

[0073] Further, the rotating storage mechanism 2 can drive the cooling cabin 31 to rotate, the extending end of the refrigerator 32 is arranged inside the cooling cabin 31, the cooling cabin 31 is provided with a cold guide liquid, and the cooling cabin 31 is a central rotating shaft and is in communication with the refrigeration circulation mechanism 3 at the upper end.

[0074] Preferably, the upper end of the cooling cabin 31 rotates around the refrigerator 32.

[0075] Preferably, the cooling cabin 31 in the present embodiment is connected with the gear disc 223, the cooling cabin 31 drives the storage disc 222 to rotate, thereby driving the vertical storage frame 221 to rotate circumferentially.

[0076] Preferably, the cooling cabin 31 is arranged at the middle position of the rotating storage mechanism 2, which can facilitate the low-temperature storage of the sample boxes and sample tubes on the rotating storage mechanism 2.

[0077] Preferably, the cooling cabin 31 is arranged at the middle position of the rotating storage mechanism 2, which can facilitate the low-temperature storage of the sample boxes and sample tubes on the rotating storage mechanism 2.

[0078] Further, the rotating storage mechanism 2 comprises a driving member 21 and a rotating storage assembly 22; the driving member 21 is arranged on the sample storage cabin 1, and the rotating storage assembly 22 is arranged inside the sample storage cabin 1; the driving member 21 can drive the rotating storage assembly 22 to rotate; the rotating storage assembly 22 can store a basket, and the basket can store sample boxes.

[0079] Preferably, the driving member 21 comprises a motor and a gear transmission shaft; the motor drives the gear transmission shaft to rotate; the gear transmission shaft is in meshing connection with a gear disc 223, so as to drive the gear disc 223 to rotate, i.e., to drive the storage disc 222 to rotate.

[0080] Further, the rotating storage assembly 22 comprises vertical storage frames 221; a plurality of vertical storage frames 221 are circumferentially arranged into a storage disc 222; the upper end of the storage disc 222 is provided with the gear disc 223; and the driving member 21 can drive the gear disc 223 to rotate.

[0081] Preferably, the vertical storage frame 221 is a basket, which can store sample boxes.

[0082] Further, the sample storage cabin 1 is provided with a vertical channel mechanism 6, which can be used to store and take out the samples of the rotating storage mechanism 2.

[0083] Preferably, the vertical channel mechanism 6 can be opened or closed; in the opened state, an external scooping mechanism can be used to scoop the sample boxes on the vertical storage frame 221; and in the closed state, the external scooping mechanism cannot enter the inside of the sample storage cabin 1, so as to avoid the damage of the ultra-low-temperature environment in the inside of the sample storage cabin 1 to the components of the external scooping mechanism and the tube-picking mechanism.

[0084] Further, the vertical channel mechanism 6 comprises a vertical channel, a channel door driving member 61, a transmission member 62, and a channel door 63; the sample storage cabin 1 is provided with the vertical channel; the vertical channel is provided with the channel door 63; the channel door 63 is connected with the upper-end channel door driving member 61 through the transmission member 62; and the channel door driving member 61 drives the channel door 63 to open or close the vertical channel through the transmission member 62.

[0085] Further, the vertical channel mechanism 6 comprises a vertical channel, a channel door driving member 61, a transmission member 62, and a channel door 63; the sample storage cabin 1 is provided with the vertical channel; the vertical channel is provided with the channel door 63; the channel door 63 is connected with the upper-end channel door driving member 61 through the transmission member 62; and the channel door driving member 61 drives the channel door 63 to open or close the vertical channel through the transmission member 62.

[0086] Further, the control box 7 is provided with a power distribution system 71, a condenser 72 and a control member 73; the power distribution system 71 can distribute power to the equipment, and the condenser 72 and the control member 73 can control the temperature of the sample storage cabin 1.

[0087] Preferably, the cooling cabin 31 is a central rotating shaft, a certain amount of liquid nitrogen is added in the central rotating shaft for sealing, the Stirling machine is started, the cooling cabin 31 conducts the natural gasification and upward movement of the liquid nitrogen to the top, the liquid nitrogen is liquefied by the Stirling refrigerator 32, the liquid is automatically stored, and the automatic operation is repeated, so that the balanced cooling refrigeration effect is achieved; the high-pressure Stirling cold head and the high-pressure stainless steel shaft body form a high-pressure cavity without pressure relief.

[0088] Due to the high-pressure boiling point difference, the liquidization capacity is improved, the liquid quickly sinks and is balancedly cooled; once the liquid is added, it can be used for a lifetime, whether the power is turned on or not, and whether it is stored or not, the gasification gas of the liquid nitrogen is compressed in the cavity, which does not affect the safety of long-term storage; it is very easy to replace, upgrade, clean and disinfect, and the like.

[0089] In summary, the cooling cabin 31 can be driven to rotate by the rotating storage mechanism 2, the liquid in the cooling cabin 31 is gasified and rises into the refrigerator 32, the refrigerator 32 converts the gasified nitrogen into liquid nitrogen, and flows into the bottom of the cooling cabin 31, so that the gasified nitrogen is circulated and liquefied, thereby circulating the liquid nitrogen for refrigeration; the cooling cabin 31 is provided with a cooling liquid, which can further cool the liquid nitrogen, improve the cooling effect, and realize one-time liquid addition for a lifetime, thereby greatly reducing the use cost of the liquid nitrogen. Embodiment 3

[0090] Referring to FIGS. 9 and 10, the third embodiment of the present application is based on the first embodiment, and the automatic adjustable low-temperature storage device comprises a sample storage cabin 1, a rotating storage mechanism 2 and a refrigeration circulating mechanism 3; the sample storage cabin 1 is provided with the rotating storage mechanism 2, the rotating storage mechanism 2 can rotate in the sample storage cabin 1, and the basket is stored, the sample is stored on the basket, and the refrigeration circulating mechanism 3 can refrigerate the sample storage cabin 1.

[0091] Specifically, the sample storage cabin 1, the rotating storage mechanism 2 and the refrigeration circulating mechanism 3; the sample storage cabin 1 is provided with the rotatable rotating storage mechanism 2, the sample storage cabin 1 is provided with the refrigeration circulating mechanism 3, the refrigeration circulating mechanism 3 can circulate the refrigeration of the sample storage cabin 1, and the rotating storage mechanism 2 can store the sample.

[0092] Preferably, the refrigeration circulating mechanism 3 is a Stirling refrigeration.

[0093] Preferably, the refrigeration cycle mechanism 3 can cycle refrigeration to the sample storage cabin 1, so that refrigeration can be performed in the sample storage cabin 1 even in the case of power failure, thereby avoiding damage to the sample due to power failure.

[0094] Further, the refrigeration cycle mechanism 3 comprises a cooling cabin 31 and a refrigeration machine 32; the cooling cabin 31 is arranged inside the sample storage cabin 1 and inside the rotary storage mechanism 2, and the refrigeration machine 32 is arranged above the sample storage cabin 1; the upper end of the cooling cabin 31 is in communication with the refrigeration machine 32, and the refrigeration machine 32 can receive the nitrogen gas vaporized in the cooling cabin 31 and liquefy the nitrogen gas and return it to the cooling cabin 31.

[0095] Further, the rotary storage mechanism 2 can drive the cooling cabin 31 to rotate; the cooling cabin 31 is a center shaft integrated structure, and liquid nitrogen is arranged in the cooling cabin 31.

[0096] Preferably, the cooling cabin 31 is a center shaft integrated structure in the embodiment, the shaft is hollow and a certain amount of liquid nitrogen is injected into the shaft and sealed,

[0097] Moreover, the center shaft can rotate at an angle of 0-190°, and of course, it can also be designed to rotate at an angle of 360°; the structure, liquid addition and assembly, and the thick-walled hollow stainless steel pipe are processed at both ends according to the requirements of the rotating shaft, and the Stirling and the shaft can adopt a clamp hoop mode.

[0098] First, the cooling cabin 31 shaft is vertically inserted into liquid nitrogen for cooling and liquid addition, then the Stirling refrigeration machine 32 is connected to the shaft by a clamp hoop, and after debugging, the whole finished product can be naturally stored.

[0099] It should be noted that:

[0100] ①Stirling liquid-gas integrated cold-conducting shaft.

[0101] A certain amount of liquid nitrogen is added into the shaft and sealed, the Stirling refrigeration machine 32 is started, the liquid nitrogen gas is conducted upward to the top of the shaft, is liquefied by the Stirling refrigeration machine 32, and is automatically stored downward, and the process is repeated automatically to achieve the effect of balanced cold-conducting refrigeration.

[0102] ②A high-pressure Stirling cold head and a high-pressure stainless steel shaft body form a high-pressure cavity without pressure relief.

[0103] ③The high-pressure boiling point difference improves the liquefaction capacity and the liquid quickly sinks to uniformly cool.

[0104] ④Once the liquid is added, it can be used for a lifetime, and whether the power is on or off or the product is stored, the gas generated by the liquid nitrogen is automatically compressed in the cavity without affecting the safety of long-term storage.

[0105] ⑤It is very easy to replace and upgrade, and easy to clean and disinfect.

[0106] Further, the sample storage cabin 1 is provided with a driving member 21 at the upper end, the cooling cabin 31 is provided with a gear disc 223 at the upper end, and the gear disc 223 is arranged at one side of the driving member 21. The driving member 21 can drive the gear disc 223 and the cooling cabin 31 to rotate. The sample storage cabin 1 is internally provided with a rotating storage assembly 22. The cooling cabin 31 can drive the rotating storage assembly 22 to rotate.

[0107] Preferably, the driving member 21 adopts a motor and a transmission gear. The transmission gear is engaged with the gear disc 223, so as to drive the cooling cabin 31 to rotate, and drive the rotating storage assembly 22 to rotate.

[0108] Preferably, the upper end of the cooling cabin 31 penetrates the sample storage cabin 1 and is communicated with the refrigerating machine 32. The refrigerating machine 32 and the cooling cabin 31 can adopt a hoop mode. That is, the refrigerating machine 32 will not rotate when the cooling cabin 31 rotates.

[0109] Preferably, the cooling cabin 31 is arranged at the middle position of the rotating storage mechanism 2, so as to conveniently perform low-temperature refrigeration on the sample boxes and sample tubes on the rotating storage mechanism 2.

[0110] Preferably, the liquid nitrogen in the cooling cabin 31 can be naturally vaporized. The vaporized nitrogen gas enters the upper end. The refrigerating machine 32 liquefies the vaporized nitrogen gas and flows into the bottom end of the cooling cabin 31 again, so as to perform circulating refrigeration. Even in the case of power failure, the circulating refrigeration can be performed.

[0111] Preferably, in the embodiment, no refrigerant medium is needed, which is environmentally friendly and saves liquid nitrogen, thereby reducing the cost.

[0112] Further, the rotating storage assembly 22 comprises vertical storage frames 221. A plurality of vertical storage frames 221 are circumferentially arranged to form a storage disc 222. The storage disc 222 is provided with a rotating disc 225 at the upper end. The rotating disc 225 is connected with the cooling cabin 31. The cooling cabin 31 can drive the rotating disc 225 and the storage disc 222 to rotate.

[0113] Further, the sample storage cabin 1 is provided with a vertical channel mechanism 6. The vertical channel mechanism 6 can be used to store and take out the samples of the rotating storage mechanism 2.

[0114] Preferably, the vertical channel mechanism 6 can be opened or closed. In the opened state, an external shoveling mechanism can shovel the sample boxes on the vertical storage frames 221. In the closed state, the external shoveling mechanism cannot enter the inside of the sample storage cabin 1, so as to avoid that the ultra-low-temperature environment in the sample storage cabin 1 damages the components of the external shoveling mechanism and the tube-picking mechanism.

[0115] Further, the vertical passage mechanism 6 comprises a vertical passage, a passage door driving element 61, a transmission element 62 and a passage door 63, the vertical passage is arranged on the sample storage cabin 1, the passage door 63 is arranged in the vertical passage, the passage door 63 is connected with the upper end passage door driving element 61 through the transmission element 62, and the passage door driving element 61 drives the passage door 63 to open and close the vertical passage through the transmission element 62.

[0116] Further, the control box 7 is arranged on the side of the sample storage cabin 1, and the control box 7 can control the temperature of the sample storage cabin 1.

[0117] Further, the control box 7 is arranged on the side of the sample storage cabin 1, and the control box 7 can control the temperature of the sample storage cabin 1.

[0118] In conclusion, the Stirling refrigerating machine 32 and the cooling cabin 31 are integrated, the consumption of liquid nitrogen is reduced, the cost of long-term use is reduced, the Stirling refrigerating machine 32 is convenient to disassemble, replace, clean and disinfect, the Stirling refrigerating machine 32 is more energy-saving and environmentally friendly, the use cost is reduced, the liquid nitrogen is liquefied once, and the liquid nitrogen is used for a lifetime, whether the power is turned on or not, the vaporized liquid nitrogen can be liquefied through the Stirling refrigerating machine 32, the liquid nitrogen is recycled, no refrigerant medium is needed, the environment is more friendly, the temperature in the sample storage cabin 1 can be automatically adjusted to +5 DEG C to -200 DEG C, and the liquid nitrogen cost is greatly saved.

[0119] It is important to note that the construction and arrangement of the application shown in the various exemplary embodiments is illustrative only. Although only a few embodiments have been described in detail in this disclosure, those skilled in the art who review the present disclosure will readily appreciate that many modifications can be made to the embodiments without departing from the spirit and scope of the application, as described in the claims (e.g., variations in sizes, dimensions, structures, shapes and proportions of the various elements, values of parameters, mounting arrangements, use of materials, colors, orientations, etc. and the like). For example, the position of elements can be reversed or otherwise varied and the nature or number of elements can be altered or varied. Accordingly, all such modifications are intended to be included within the scope of the present application. The order or sequence of any process or method steps can be varied or re-sequenced without departing from the spirit of the application. Any "apparatus" or "device" described herein can be embodied in many different forms and a "means" for performing any function described herein can include any of the apparatus or structures described herein. In the claims, any means-plus-function clause is intended to cover the structures described herein as performing the recited function and not only structural equivalents but also equivalent structures. Other substitutions, modifications, changes and omissions can be made in the design, operating conditions and arrangement of the exemplary embodiments without departing from the scope of the present application. Accordingly, the present application is not limited to the particular embodiments described in the specification.

[0120] In addition, for purposes of brevity of description, it is not the intention of the

[0121] It will be appreciated that in the development of any actual implementation, as in any engineering or design project, numerous implementation-specific decisions can be made. Such development efforts can undoubtedly be complex and time-consuming, but would nevertheless be a routine undertaking for those of ordinary skill in the art having the benefit of this disclosure.

[0122] It should be noted that the above-mentioned embodiments are only used to illustrate the technical solutions of the present application but not to limit the present application, and although the present application is described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present application can be modified or equivalent replaced without departing from the spirit and scope of the present application, and all should be included in the scope of the claims of the present application.

Claims

1. An automatically adjustable cryogenic storage device, characterized by: Including sample storage cabin (1), rotating storage mechanism (2) and refrigeration cycle mechanism (3);The sample storage cabin (1) is provided with rotatable rotating storage mechanism (2), and the sample storage cabin (1) is provided with refrigeration cycle mechanism (3), the refrigeration cycle mechanism (3) can be circulated to the sample storage cabin (1) refrigeration, the rotating storage mechanism (2) can store sample.

2. The automatically adjustable cryogenic storage device of claim 1, wherein: The refrigeration cycle mechanism (3) includes cooling cabin (31) and refrigerator (32);The cooling cabin (31) is arranged inside the sample storage cabin (1), and is arranged on the inside of the rotating storage mechanism (2), the refrigerator (32) is arranged above the sample storage cabin (1), the upper end of the cooling cabin (31) is communicated with the refrigerator (32), the refrigerator (32) can receive the nitrogen gas vaporized in the cooling cabin (31), and the nitrogen gas is liquefied and returned to the cooling cabin (31).

3. The automatically adjustable cryogenic storage device of claim 2, wherein: The cooling cabin (31) is a liquid nitrogen tank, and is fixedly arranged in the sample storage cabin (1), the liquid nitrogen tank is provided with a liquid adding system.

4. The automatically adjustable cryogenic storage device of claim 3, wherein: The refrigerator (32) includes refrigeration module (321), first pipeline (322) and second pipeline (323);The upper end of the first pipeline (322) and the second pipeline (323) is connected with the refrigeration module (321), the lower end of the first pipeline (322) is arranged at the upper position of the cooling cabin (31), and the lower end of the second pipeline (323) is arranged at the lower position of the cooling cabin (31).

5. The automatically adjustable cryogenic storage device of claim 3, wherein: The upper end of the cooling cabin (31) is also provided with a control mechanism (4), and the control mechanism (4) can refrigerate the cooling cabin (31).

6. The automatically adjustable cryogenic storage device of claim 3, wherein: The upper end of the cooling cabin (31) is also provided with a pressure relief assembly (5), and the pressure relief assembly (5) can exhaust the cooling cabin (31).

7. The automatically adjustable cryogenic storage device of claim 2, wherein: The rotating storage mechanism (2) can drive the cooling cabin (31) to rotate, the extension end of the refrigerator (32) is arranged in the cooling cabin (31), the cooling cabin (31) is provided with a cooling liquid, and the cooling cabin (31) is a central rotating shaft and is communicated with the refrigeration cycle mechanism (3).

8. The automatically adjustable cryogenic storage device of claim 2, wherein: The rotating storage mechanism (2) can drive the cooling cabin (31) to rotate, the cooling cabin (31) is a central rotating shaft integrated structure, and the cooling cabin (31) is provided with liquid nitrogen.

9. An automatically adjustable cryogenic storage device according to any one of claims 1 to 7, characterized in that: The rotating storage mechanism (2) includes driving part (21) and rotating storage assembly (22);The sample storage cabin (1) is provided with driving part (21), the rotating storage assembly (22) is arranged in the sample storage cabin (1), the driving part (21) can drive the rotating storage assembly (22) to rotate, and the rotating storage assembly (22) can store the basket.

10. The automatically adjustable cryogenic storage device of claim 9, wherein: The rotating storage assembly (22) includes vertical storage frame (221), and a plurality of vertical storage frames (221) are circumferentially arranged into storage disc (222), the upper end of the storage disc (222) is provided with gear disc (223), and the driving part (21) can drive the gear disc (223) to rotate.

11. The automatically adjustable cryogenic storage device of claim 8, wherein: The sample storage cabin (1) is provided with a driving member (21) at the upper end, the cooling cabin (31) is provided with a gear disc (223) at the upper end, and the gear disc (223) is arranged at one side of the driving member (21), the driving member (21) can drive the gear disc (223) and the cooling cabin (31) to rotate, and the sample storage cabin (1) is internally provided with a rotating storage assembly (22), and the cooling cabin (31) can drive the rotating storage assembly (22) to rotate.

12. The automatically adjustable cryogenic storage device of claim 11, wherein: The rotating storage assembly (22) comprises vertical storage frames (221), a plurality of groups of the vertical storage frames (221) are circumferentially arranged into a storage disc (222), the storage disc (222) is provided with a rotating disc (225) at the upper end, the rotating disc (225) is connected with the cooling cabin (31), and the cooling cabin (31) can drive the rotating disc (225) and the storage disc (222) to rotate.

13. An automatically adjustable cryogenic storage device as claimed in any of claims 1 to 8, characterized in that: The sample storage cabin (1) is provided with a vertical channel mechanism (6), and the sample of the rotating storage mechanism (2) can be accessed through the vertical channel mechanism (6).

14. The automatically adjustable cryogenic storage device of claim 13, wherein: The vertical channel mechanism (6) comprises a vertical channel, a channel door driving member (61), a transmission member (62) and a channel door (63), the sample storage cabin (1) is provided with a vertical channel, the vertical channel is internally provided with the channel door (63), the channel door (63) is connected with the channel door driving member (61) at the upper end through the transmission member (62), and the channel door driving member (61) drives the channel door (63) to open and close the vertical channel through the transmission member (62).

15. An automatically adjustable cryogenic storage device as claimed in any of claims 1 to 8, characterized in that: Further comprising a control box (7), the control box (7) is arranged at the side of the sample storage cabin (1), and the control box (7) can control the temperature of the inside of the sample storage cabin (1).

16. The automatically adjustable cryogenic storage device of claim 15, wherein: The control box (7) is internally provided with a power distribution system (71), a condenser (72) and a control member (73), the power distribution system (71) can distribute power to the equipment, and the condenser (72) and the control member (73) can control the temperature of the sample storage cabin (1).

Citation Information

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