Medication reminder device for alzheimer's patients with remote monitoring, cooling, and shock-absorbing features

Abstract

A Medication reminder device for Alzheimer's patients comprises a main body (15) with multiple drawers (a10 to d10) around a display screen (7). The device features a holding mechanism (11) with sliding arms (11.1) and compression springs (11.4) for secure storage, and a multilayer protection system (13) incorporating cooling gel (13.1), shock-absorbing foam (13.2), and thermal insulation (13.4). A shock- absorbing mechanism (16) with springs (19), screws (18), and a finned holder (17c) ensures stability. Illuminated status indicators on each drawer (a1 to d1) and smartwatch integration enable real-time medication monitoring via a data transfer module (27). Additional features include vibrators (23) on drawer doors with gelatin bases (24) for precise vibration, high-tensile springs or thermoplastic elastomers (TPE) for durability, and a silica gel container (12.4) in the replacement medicine box for humidity control. Strategically designed fins (17c) with holes enhance the holder's functionality and secure connections.

Description

DescriptionTitle of Invention : Medication Reminder Device for Alzheimer's Patients with Remote Monitoring, Cooling, and Shock-Absorbing FeaturesTechnical Field

[0001] The present invention relates to a multifunctional medication reminder device designed specifically for individuals with Alzheimer's disease. More particularly, it pertains to a device that facilitates the organization, storage, and timely administration of medications through a combination of mechanical, electronic, and software components.Background Art

[0002] Alzheimer's disease often impairs patients' memory and cognitive functions, making it challenging for them to adhere to prescribed medication regimens. Consequently, there exists a need for an innovative device that not only stores medications but also reminds patients to take their medications at the appropriate times.

[0003] Many caregivers of older adults undergoing treatment lack a patient monitoring system, which is crucial for ensuring adherence to treatment schedules and correcting any detected anomalies. Additionally, not all patients or caregivers receive advice on the best times to take prescribed medications for optimal results or which medicines should not be administered together due to potential health risks or loss of efficacy from pharmacokinetic, pharmacodynamics, or psycho-chemical interactions.

[0004] While some existing devices fulfill certain functions of the present invention, none integrate all features or include the novel functionalities of this invention. Current devices often overwhelm users with complicated interfaces, many buttons, and displays, leading to rejection by patients or caregivers. They also fail to assist caregivers in managing complex medication regimens.

[0005] Several patent documents (e.g. US2012316405, WO2016141102, US20050059924, US20110170378 and WO0217850) address drug dispensing and patient monitoring systems, using microprocessor systems andcommunication modules, but lack some other functionalities. Customized electronic devices for measuring patient adherence tend to be more accurate but expensive.

[0006] Prior art includes various devices that enhance basic pill organizers but are often restricted to tablets and capsules. Many medication forms, such as inhalers, injections, eye drops, liquid medications, and blister packs, are not easily accommodated by pill tray bins. For example:

[0007] US. Pat. Application No. US20220139519 discloses a smart pill organizer, or pillbox, helps patients follow to their medication schedules by recording and remotely monitoring medicine usage. It supports both the patient and a guardian (such as a family member or healthcare provider) through a web interface, emails, and texts. The pillbox accommodates various dose types, including pills in trays, external doses in original containers, and remote doses taken away from home, with frequencies ranging from monthly to multiple times daily. The pillbox features two weekly pill trays with custom electronics for reminders, adherence monitoring, and communication. LEDs and voice messages guide the patient, while remote access is possible via web or text commands, providing real-time adherence data. Additional features include remote environmental monitoring (e.g., temperature) and customizable reminders. The guardian can oversee patient adherence and receive notifications about medication intake and environmental conditions.

[0008] US. Pat. Application No. US20210022962 discloses an intelligent device connected to the internet that ensures the safe storage and automatic, controlled delivery of medicines. It also allows for health checks using data from peripheral devices, enhancing patient compliance with pharmacological treatments through continuous monitoring. The system comprises an electromechanical device featuring an inner disk with compartments for storing medicines, a gate for controlled access, and various optical sensors for position and removal detection. Container vessels are stored in the compartments, with magnets aiding in their positioning. The gate mechanism is controlled by an electric motor and equipped with sensors, while a lid and housing cover and enclose the electromechanical components. Intelligent peripheral devices take biometric measurements and send alerts, and a control unit receives information from a remote softwareapplication for managing medicine loading and delivery. The device operation can be managed wirelessly via a software application and includes modules to monitor and manage the internal environment and patient biometric data. This system aims to improve medication management and patient monitoring, providing reliable information and ensuring adherence to treatment plans.Summary of Invention

[0009] This summary is provided to introduce some concepts in simplified form that are further described below in the Detailed Description. This summary is not intended to identify key features or essential features of the claimed subject matter.

[0010] The medication reminder device described herein offers extensive industrial applicability in healthcare settings, addressing the medication management needs of a diverse patient population, including elderly individuals, patients with disabilities, and those diagnosed with Alzheimer’s disease. It comprises three primary sections: mechanical, electronic, and software, each designed for optimal functionality and user-friendliness. The mechanical section features a main body with multiple trapezoidal drawers for medications with various intervals, an ergonomically designed access mechanism, and specialized compartments for syrups, vials, and bulk medications. Advanced components, such as moistureabsorbing materials, spring-loaded bottle holders, and shock-absorbing mechanisms, safeguard medication integrity and usability. The electronic section includes LED indicators, vibrators for visually impaired patients, high-resolution displays, humidity and temperature sensors, and advanced alarm systems with bilingual audio reminders. The software section supports remote monitoring through a smartphone application and smartwatch, providing real-time updates, connectivity via Wi-Fi and Bluetooth, and features such as data logging, Al-driven analytics, and telehealth integration. This multifunctional device ensures precise, reliable, and personalized medication adherence, offering a comprehensive solution for modern healthcare need.Technical Problem

[0011] Alzheimer's is a leading cause of death worldwide, affecting both the elderly and some younger individuals with dementia. Symptoms include severe memoryloss, inability to perform daily tasks, and impaired judgment, often leading to depression and death. Medication can slow the disease's progression, making adherence to prescribed treatment crucial. Devices for Alzheimer's patients must account for poor vision, hearing issues, and illiteracy, and ensure temperature control for medications. Safety in transporting medicinal vials should also be considered. Continuous monitoring and proper medication management are essential for improving the quality of life for Alzheimer's patients.

[0012] Despite the wide variety of medicine holders available on the market, a specialized device designed specifically for Alzheimer's patients, incorporating remote monitoring and addressing the unique needs of the elderly, has yet to be developed. Additionally, integrating cooling and shock-absorbing features would enhance the device's efficiency, reduce the risk of medication degradation, and prevent potential drug poisoning during both daily and long-term transportation. These features would also safeguard fragile medications from physical damage, which has not been adequately addressed in existing models.

[0013] Moreover, the application of this device is not limited to Alzheimer's patients. It can be beneficial for a wide range of patients, including those with other chronic conditions who require regular medication. Even for healthy individuals who need to manage their medications effectively, this device offers a reliable and advanced solution for ensuring proper medication usage and safetyAdvantageous Effects of Invention

[0014] Based on the previously presented statistics regarding the number of Alzheimer's patients and the challenges they face with medication adherence, a dedicated device for such patients is essential. This device should include new features in addition to existing ones like alarms and drug classification to effectively address these challenges. The device incorporates some unique parameters that set it apart from previous models:

[0015] Unlike many existing drug reminder boxes that only feature temperature warnings, this device includes a built-in cooler for medicinal bottles. The cooling part can maintain a lower temperature for longer periods compared to regular ice, ensuring the integrity of temperature-sensitive medications.

[0016] Given the susceptibility of Alzheimer's patients to dropping the device, it is crucial to have a shock absorption system for the medicinal bottles, which often have fragile packaging. This device incorporates two shock absorption systems, detailed in the mechanical properties section, to protect the medications from damage.

[0017] In addition to using LED lights(22) and an alarm with sound recording capability, this device includes a vibrator on each box door. This feature is designed to assist patients with vision impairments, allowing them to identify the specific drawer containing the medication by touch.

[0018] These improvements make the device significantly more effective in addressing the specific needs of patients, ensuring better medication adherence and overall care.Brief Description of Drawings

[0019] Some embodiments are illustrated by way of example and not limitation in the figures of the accompanying drawings in which:

[0020] Figure 1 shows an isometric view of the device.

[0021] Figure 2 shows a top view of the device.

[0022] Figure 3 shows a view of the device, in which parts such as the hinged doors and vial holder are shown.

[0023] Figure 4 shows the details of the holding mechanism and its function.

[0024] Figure 5 shows an exploded view of the holding mechanism and its components.

[0025] Figure 6 shows a top view of the holding mechanism.

[0026] Figure 7 shows an exploded view of the replacement drug compartment.

[0027] Figure 8 shows an exploded view of a multilayer protection mechanism for safeguarding vial.

[0028] Figure 9 shows an exploded view of the shock-absorbing mechanism.

[0029] Figure 10 shows an isometric view of the main body, the bottle holding mechanism and other components.

[0030] Figure 11 shows an exploded view of the device and its interior components such as sensors, LED’s and screws.

[0031] Figure 12 shows the connection between the device and the data transmission system and intelligent electronic devices.Description of Embodiments

[0032] The following describes embodiments of the present invention in detail, with reference to the accompanying drawings. However, unless explicitly stated otherwise, the dimensions, materials, shapes, relative positions, and similar details of the components described are to be considered as illustrative only, and should not be interpreted as limiting the scope of the invention.

[0033] Likewise, terms describing shapes, such as “rectangular” or “cylindrical,” are not limited to the strict geometric definition. These terms also include shapes with slight deviations, such as unevenness or chamfered corners, as long as the same effect is achieved.

[0034] Furthermore, terms like “comprise,” “include,” “have,” “contain,” and “constitute” are not intended to exclude the presence of other components.

[0035] The medication reminder device described herein possesses extensive industrial applicability within healthcare environments, enhancing medication management for a diverse range of patients. This includes, but is not limited to, elderly individuals and those with disabilities, as well as patients diagnosed with Alzheimer’s disease. The device is designed to support all patients requiring assistance with medication adherence, thereby broadening its utility beyond a specific patient demographic.

[0036] The invention comprises a complex assembly of various components, which will be elaborated upon in the subsequent sections. To enhance clarity regarding the structure and functionality of each component, the device is categorized into three primary sections: the mechanical section, the electronic section, and the software section.

[0037] Mechanical Section:

[0038] An isometric view of the mechanical component of the device (100), designed to assist Alzheimer's patients in medication adherence, is depicted in Figure 1 .The mechanical structure includes a main body (15) characterized by a circular cross-section in the exemplary embodiment of the invention. Within this body, multiple compartments, herein referred to as drawers (a10 to d10), are arranged to house patient consumables, including various medications.

[0039] In the preferred embodiment of the invention, the device comprises multiple drawers (a10 to d10), exemplarily four but not limited to this quantity, each designated for storing medications with differing consumption intervals (e.g., 6 hours, 8 hours, 12 hours, and 24 hours). Each drawer features a trapezoidal cross-section with smoothly contoured and bent edges, facilitating radial arrangement around a central display screen (7). This design optimizes user accessibility to medications while maximizing internal storage efficiency.

[0040] The device further incorporates several access doors (a1 to d1 ) attached to the main body via a hinge mechanism. Users can open these drawer doors by applying pressure on an ergonomically designed tab, thereby gaining access to the contents within.

[0041] Additionally, the main body comprises specialized assemblies(13) for storing medicinal bottles as syrups, vials (13.5), and an ordinary replacement drug compartment (12). The said compartment(12) is particularly crucial for accommodating medications supplied in bulk containers that are not suitable for portable storage solutions. The said replacement drug compartment, ensure the preservation of medication quality and prevent moisture absorption. Fig.7 illustrates this compartment along with detailed component specifications. Within this compartment resides a cylindrical container (12.4) housing a moistureabsorbing agent as silica gel (12.3). The silica gel's role is pivotal in maintaining an optimal humidity level within the compartment (12.5). The cylinder(12) is secured to its lid (12.2) via internal stabilizing pins (12.6), which are precisely fitted into corresponding apertures in the lid. This design ensures a robust yet accessible connection between the cylinder body and its lid, allowing for straightforward replacement of the silica gel when necessary. The cylindrical assembly is specifically designed to store and safeguard silica gel while preventing direct contact with stored medications. This configuration provides a controlled environment conducive to preserving medication integrity by mitigating moisture exposure. Additionally, the compartment features a primary lid (12.1 )that serves as a protective barrier against external moisture and air infiltration. To ensure the preservation of medication quality and prevent moisture absorption, the device integrates a standard compartment designated as a replacement medicine box(12).

[0042] As shown in Figs. 4,5&6, in one embodiment of invention, the device is equipped with a bottle holding mechanism (11 ) engineered to securely retain medicinal bottles within the designated chamber, thereby preventing any risk of tipping, breakage, or spillage. This mechanism is adjustable, allowing it to accommodate a diverse range of bottle sizes and shapes, including but not limited to cylindrical, oval, or rectangular configurations. It comprises two horizontally sliding arms (11.1 ) strategically positioned on either side of the chamber, facilitating the placement of syrups with varying dimensions. Each arm features a receiving head designed with a curved cross-section that conforms to the outer surface of the syrup bottle. This ergonomic design ensures that the bottle is firmly and stably positioned at the center of the holder. The curvature and semicircular profile of the arms promote optimal balance, effectively preventing any slipping or unwanted lateral movement during operation. Additionally, the edges of the arms are gracefully contoured to make gentle contact with the bottle, thereby minimizing the risk of scratching or damaging the bottle's surface.

[0043] The main structural components of the holder consist of two interlocking parts (11 .3 and 1 1 .5), which are securely fastened together using some screws (11 .6). The terminal sections of the arms are designed as tabs featuring a unique design wherein these tabs (11 .7) are enclosed within a groove formed between the two parts (11 .3 and 1 1 .5), thus restricting the movement of the arms to a specific linear direction while allowing for optimal functionality.

[0044] A compression spring (11 .4) is installed behind each arm, anchored securely through a holding hook component (11 .2). These springs facilitate a smooth return of the arms to their original position after adjustment, ensuring that the syrup bottles are held securely in place. This mechanism has been meticulously designed not only for safety but also for ease of use, allowing users to replace and reposition medicinal syrups within the device without requiring specialized tools or excessive force.

[0045] To further safeguard the medication vials and mitigate potential damage, the device incorporates a multilayer protection mechanism(13) for protecting small bottles or vial(13.5) as shown in Fig. 8. This mechanism consists of several different layers, each serving a specific function to protect and stabilize the vials under various environmental conditions.

[0046] Cooling gel layer (13.1 ) is positioned closest to the vial (13.5) and is specifically designed to maintain a low and consistent temperature, particularly in situations where ambient temperatures exceed optimal levels. For example, where temperatures below ambient are required, a cylindrical chamber containing cooling gels can be placed around the vial, located between the vial and a shockabsorbing foam layer (13.2). The micro-springs(13.3) within the said layer are compressed to create sufficient space for the cooling chamber. It is noteworthy that in its gel state, the cooling gel also functions effectively as both a shock absorber and protector for the vial. One embodiment of this invention utilizes a water-based polyacrylate gel; however, alternatives such as silicone-based gels or phase change materials may also be employed to achieve similar thermal regulation properties.

[0047] Shock-absorbing foam layer (13.2) is positioned adjacent to the cooling gel layer, this foam provides an additional barrier against impacts and vibrations, ensuring that the vials remain stable and protected during transport or handling. Various materials such as ethylene-vinyl acetate (EVA) foam or polyurethane foam may be considered for this layer due to their dampening properties. The cylindrical assembly serves to house silica gel for moisture absorption, preventing direct contact with the medication while creating a controlled environment conducive to maintaining medication integrity.

[0048] In the second layer, a shock-absorbing foam (13.2) encloses the vial (13.5) located within the cooling gel layer (13.1 ). This foam serves as a protective buffer which minimize the transmission of sudden shocks and vibrations from the device's hard exterior to the fragile vial surface. While high-density polyurethane is one embodiment of the shock-absorbing foam material, alternative materials such as ethylene-vinyl acetate (EVA) or viscoelastic gel can also be utilized to enhance flexibility and impact resistance.

[0049] In the middle layer, positioned between the shock-absorbing foam (13.2) and the thermal insulation layer (13.4), are shock-absorbing micro-springs. These springs are engineered to manage and dissipate sudden impacts to the vial, particularly during instances of severe device shaking. The micro-springs can be designed in various configurations, including small spiral or flat designs, arranged in a tailored array that conforms to the vial's shape and volume. This optimized arrangement ensures maximum contact with the shock-absorbing foam, allowing for even distribution of forces.

[0050] Upon experiencing a shock or impact, these springs compress to absorb mechanical energy and then return to their original state once the force decreases. This reversible characteristic prevents impact forces from being transmitted to the vial, maintaining its stability and safety. By absorbing and controlling applied forces, the springs keep the vial stationary, further protection it from potential damage.

[0051] The outermost layer, dedicated to thermal insulation (13.4), plays a key role in thermally isolating the vial from external environmental effects. This insulation can be constructed from materials such as nitrile foam or aerogel composites, which are known for their superior thermal resistance. The insulation adheres securely to the inner wall of the chamber, significantly reducing heat transfer to the vial.

[0052] In addition to these protective features, as shown in Figs.9&10 a spring-type shock-absorbing mechanism (16) is integrated into the device to protect it against impacts resulting from accidental drops. The main components of this mechanism comprises a holder (17), which resembles a robust holding frame with side arms and features a central section (17a) designed to protect holding assembly (11). The central section comprises a plate with a circular crosssection, enhanced by attached fins (17c) that cradle the syrup holding assembly. Earring parts (17b) are installed on both sides of the holder (17) to provide additional stability and support for the vial assembly (13). In one embodiment, the holder has a cylindrical shape, which effectively secures the vial assembly. However, alternative shapes such as an oval or hexagonal cross-section may be considered to enhance grip and distribute stress during impacts. Additionally, utilizing a modular design that allows for customization in size couldaccommodate various vial dimensions while maintaining structural integrity. The shock-absorbing mechanism(16) furthermore comprises a combination of at least a screw (18) and at least a spring (19). In the main embodiment of the invention, multiple springs are arranged and connected to the bottom crosssection of the holding structure using durable pins. Each spring's configuration can be optimized by selecting materials such as high-tensile steel or advanced polymers like thermoplastic elastomers (TPE) for improved elasticity and durability. The springs can be designed in various shapes, including conical or barrel forms, which may enhance energy absorption characteristics. The said embodiment comprises a mechanism where one end of each spring remains free while the other end is securely attached to the holding body. Upon application of sudden or shock forces, the springs compress, changing length and gradually releasing pressure at a controlled rate. This characteristic ensures that shock forces are not directly transmitted to sensitive components, such as the bottle and vial holding assemblies. Instead, the springs effectively dissipate the stored energy, significantly reducing shock impact.

[0053] The bent edges(17d) of the fins in the central holding section (17a) are designed with strategically placed holes to accommodate the screw and spring connections. This feature not only secures the holder to the body of the device but also enhances impact absorption capabilities in the event of a fall. To further optimize the said feature, alternative materials such as reinforced nylon or composite materials could be utilized for the fins, providing enhanced rigidity while remaining lightweight.

[0054] The main device features a central screen display (7), located on the main body, ensuring clear visibility for users in one embodiment of the invention. Each drawer door is equipped with its own Illuminated status indicator (e.g. LED indicator), which illuminates when an alarm is activated. This visual sign assists patients in identifying which medications are stored in each drawer, enabling easy access even in emergency situations. To improve user experience, consider integrating color-coded LEDs or additional visual indicators that correspond to specific medications or alerts. This improvement would further aid patients in distinguishing between different medications quickly.

[0055] Another feature of the device is the presence of vibrators(23) installed on each drawer's door, specifically designed for patients with visual impairments. These vibrators are mounted on a specially designed gelatin base(24) within each drawer. The gelatin base serves to effectively transmit vibrations produced by the vibrator(23) directly to the surface of the drawer door without affecting adjacent drawers. At the appointed time for medication intake, only the vibrator corresponding to the relevant drawer is activated. This targeted vibration alerts the patient to which drawer contains their required medication. The design minimizes vibration interference between drawers, thereby enhancing operational accuracy.

[0056] To further improve this feature, consider utilizing adjustable vibration intensity settings or incorporating haptic feedback technology that varies based on urgency or type of medication. Additionally, employing materials with superior acoustic properties for the gelatin base could enhance vibration transmission efficiency, ensuring that patients receive clear tactile notifications.

[0057] In the preferred embodiment of invention, the device is equipped with a high- resolution display (7) that indicates the daily medication status, facilitating user awareness of their medication schedule. An integral alarm system is combined into the device's electronic mainboard (9), allowing users to set alarms at customizable intervals of 6, 8, 12, or 24 hours. The audio alarm system is designed to emit different sounds for each set interval, aiding users in distinguishing between multiple doses.

[0058] Furthermore, in one embodiment of invention, the device supports bilingual notifications in local language and English, enhancing accessibility for various users. Another feature of the present invention is its ability to record and play back audio reminders, enabling users to receive personalized medication prompts in the comforting voices of their family members. For instance, the alarm designated for 6-hour medications may utilize a recorded message from a loved one, thereby fostering emotional support and reducing anxiety related to medication adherence. This personalized approach effectively mitigates confusion regarding alarm associations with specific dosages.

[0059] An internal memory module is integrated into the device, capable of recording and storing comprehensive data regarding medication consumption patterns. This includes timestamps for each administered dose as well as records of any missed doses. Additionally, the memory logs any alerts triggered by temperature or humidity fluctuations, with all entries timestamped for accuracy. This functionality enables users or caregivers to generate detailed reports on medication adherence and storage conditions, facilitating informed discussions with healthcare providers.

[0060] Positioned on each drawer's door, as shown in Fig.11 , the infrared sensor (3) employs a transmitter-receiver mechanism to detect variations in ambient light levels. This capability allows the device to determine whether a drawer is full or empty, thus enhancing user confidence in medication management practices. Within each drawer door, at least a magnetic sensor(4) serves a dual function: it detects whether the device's door is open or closed while at the same time securing it shut through a robust magnetic mechanism. This design feature prevents accidental openings, so ensuring that medications remain safely stored and protected from unauthorized access or environmental exposure.

[0061] Furthermore, in one embodiment of the invention, the device is equipped with humidity and temperature sensors(not shown) that continuously monitor the environmental conditions. These sensors are adjusted to provide real-time data on internal temperature and humidity levels, ensuring that medications are stored within optimal conditions as per medical guidelines. Users can program the device to alert them when environmental parameters deviate from the pre-set thresholds, thus safeguarding the reliability and efficiency of the medications.

[0062] The medication reminder device is equipped with remote monitoring capabilities, facilitated through an application compatible with both Android and iOS operating systems. This application not only improves user interaction but also provides real-time insights into medication adherence, making it suitable for individual users as well as healthcare professionals monitoring patients in clinical settings or home care situations.

[0063] In one embodiment of the invention, a smartwatch (25) is designed to work in combination with the medication reminder device. The said smartwatch allowsusers — whether they are patients or caregivers — to monitor medication consumption and track the timing of upcoming doses at any moment. The smartwatch continuously receives data from the medication reminder device via secure Bluetooth or Wi-Fi connections(27), ensuring seamless communication and real-time updates.

[0064] This functionality enables users to effectively monitor whether prescribed doses have been taken and receive alerts concerning environmental factors such as temperature and humidity that could affect medication integrity.

[0065] The device incorporates advanced sensors, including a laser sensor strategically positioned on the drawer door, which provides real-time status updates regarding the contents of each drawer (full or empty). This information is relayed to the smartwatch, allowing users to promptly identify which medication drawers require refilling. The application also displays the status of active drawers, giving users a comprehensive overview of their medication inventory.

[0066] Information transfer between the device, smartwatch, and application is facilitated through both Wi-Fi and Bluetooth technologies. In Bluetooth mode, users can receive notifications and updates from up to 250 meters away from the device. When connected via Wi-Fi, users can exchange data regardless of distance after initial setup with the smartwatch or application, ensuring constant connectivity.

[0067] In one embodiment of the invention, the smartwatch is designed to independently display alarms for each medication schedule without requiring a real-time signal from the main system at the time of the alarm. This feature enhances reliability and ensures that users receive timely reminders even in instances of connectivity loss.

[0068] To enhance the functionality and versatility of the medication reminder device, the following components can be considered:

[0069] 1 . Cloud-Based Data Storage: Implement cloud technology for storing historical medication adherence data, allowing for easy access by healthcare providers and caregivers.

[0070] 2. Al-Driven Analytics: Integrate artificial intelligence algorithms to analyze adherence patterns and provide personalized feedback or recommendations based on user behavior.

[0071] 3. Telehealth Integration: Enable direct communication features within the application that allow healthcare professionals to consult with patients remotely regarding their medication regimens.

[0072] 4. Multi-User Capability: Design the application to support multiple user profiles, enabling family members or caregivers to monitor several patients simultaneously.

[0073] 5. Voice Activation: Incorporate voice recognition technology for hands-free operation, allowing users to query their medication status or receive reminders through voice commands.

[0074] 6. Wearable Health Monitoring: Integrate additional health monitoring sensors (e.g., heart rate, blood pressure) into the smartwatch to provide a complete view of patient health alongside medication adherence.

[0075] The software component consists of a user interface designed for ease of use by both patients and caregivers. The software enables users to program medication schedules, receive reminders, log medication intake, and track adherence over time. Furthermore, it may include features such as alerts for missed doses and periodic notifications for caregivers regarding the patient's adherence status.Industrial Applicability

[0076] This medication reminder device has broad industrial applicability in healthcare settings, improving medication management for elderly or disabled patients, including but not limited to those with Alzheimer’s. It is suitable for hospitals, nursing homes, and home care environments, ensuring accurate and timely medication administration while promoting patient independence. Its advanced storage features, such as moisture control, shock absorption, and temperature management, keep drug integrity, making it valuable across various pharmaceutical applications. The device’s connectivity via Bluetooth and Wi-Fi supports telehealth systems, enabling remote monitoring and caregiver assistance. Additionally, its software, compatible with smartphones andsmartwatches, facilitates personalized medication scheduling, adherence tracking, and environmental monitoring, enhancing overall patient care and safety.

Claims

AMENDED CLAIMS received by the International Bureau on 20 November 2025 (20.11 .2025)

1. (Amended)A medication reminder device for assisting Alzheimer’s patients with medication adherence, comprising: a) a main body (15) having a circular cross-section and including a plurality of drawers (a10 to d10) arranged radially around a central high-resolution display screen (7), each drawer configured to store medications with differing consumption intervals and equipped with an access door (a1 to d1) operable via an ergonomic tab; b) a multilayer protection mechanism (13) for storing and protecting medication vials (13.5), comprising: i) a cooling gel layer (13.1) surrounding the vial to maintain a low and consistent temperature; ii) a shock-absorbing foam layer (13.2) adjacent to the cooling gel layer; iii) a plurality of micro-springs (13.3) positioned between the foam layer and an outer thermal insulation layer (13.4) to dissipate impact forces; and iv) a cylindrical assembly (12) containing a moisture-absorbing agent (12.3) secured by internal stabilizing pins (12.6) to prevent direct contact with medications while maintaining optimal humidity; c) a bottle holding mechanism (11) with two horizontally sliding arms (11.1) having curved receiving heads and compression springs (11.4) to securely hold medicinal bottles of varying sizes and shapes; d) a spring-type shock-absorbing mechanism (16) integrated into the main body, comprising a holder (17) with a central section (17a) and fins (17d) having strategically placed holes for screw (18) and spring (19) connections to absorb impact from accidental drops; e) an electronic system comprising: i) an infrared sensor (3) and a magnetic sensor (4) on each drawer door to detect drawer status and secure closure; ii) humidity and temperature sensors configured to monitor environmental conditions and trigger alerts when parameters deviate from pre-set thresholds;iii) an internal memory module for recording medication consumption patterns, missed doses, and environmental alerts with timestamps; iv) vibrators (23) mounted on a gelatin base (24) in each drawer to provide targeted tactile notifications for visually impaired users; and v) an audio alarm system integrated into an electronic mainboard (9), configured to emit distinct sounds for medication intervals of 6, 8, 12, or 24 hours and to play personalized audio reminders recorded in the voices of family members; f) a remote monitoring system comprising a smartwatch (25) and a mobile application compatible with Android and iOS, configured to receive real-time data on medication adherence and environmental conditions via Bluetooth or WiFi connections (27), wherein the smartwatch provides alerts for upcoming doses and drawer refill status; characterized in that the device integrates the multilayer protection mechanism, the targeted vibration system with a gelatin base, and the personalized audio reminders in family members’ voices to provide a synergistic solution for Alzheimer’s patients.

2. (Amended)The medication reminder device according to claim 1 , wherein the vibrators (23) mounted on the gelatin base (24) in each drawer (a10 to d10) are configured with adjustable vibration intensity settings, and wherein the gelatin base is composed of a material with acoustic properties selected from the group consisting of silicone-based gels and viscoelastic gels, to enhance vibration transmission efficiency and minimize interference with adjacent drawers.

3. (Cancelled)

4. (Cancelled)

5. (Cancelled)

6. (Cancelled)

7. (Cancelled)

8. (Cancelled)

9. (Cancelled)

10. (Added)The medication reminder device according to claim 1 , wherein the multilayer protection mechanism (13) includes a cooling gel layer (13.1) comprising a water-based polyacrylate gel or a phase change material, and wherein the thermal insulation layer (13.4) is constructed from nitrile foam or aerogel composites, configured to maintain a stable temperature for medication vials (13.5) under ambient conditions exceeding optimal levels, and wherein the microsprings (13.3) are arranged in a spiral or flat configuration to conform to the vial’s shape for optimal force distribution.

11. (Added)The medication reminder device according to claim 1 , wherein the audio alarm system integrated into the electronic mainboard (9) supports bilingual notifications in a local language and English, and wherein the personalized audio reminders are stored in the internal memory module, allowing playback of recorded messages from family members for each medication interval (6, 8, 12, or 24 hours), thereby enhancing emotional support and reducing medication-related anxiety for Alzheimer’s patients.

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