Fatty acid ester derivatives of cannabinoid, methods of preparation thereof, and uses thereof
Fatty acid esters of CBG, synthesized with unsaturated fatty acids, address the challenge of skin permeability and bioavailability in cannabinoid formulations, providing stable and effective topical applications.
WO2026058260A1 Publication Date: 2026-03-19IMI TAMI INST FOR RES & DEV LTD
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Patent Information
- Application Number
- PCT/IL2025/050797
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-09-12
- Filing Date
- 2025-09-11
- Publication Date
- 2026-03-19
AI Technical Summary
Technical Problem
Existing cannabinoid formulations face challenges in enhancing skin permeability and bioavailability, particularly for non-psychoactive cannabinoids like CBG, with known derivatives being less pharmaceutically useful.
Method used
Synthesis of fatty acid esters of cannabinoids, specifically CBG, through ester linkages with unsaturated fatty acids, creating compounds that are miscible and compatible with carriers like Jojoba oil, enhancing skin permeability and stability.
Benefits of technology
The fatty acid esters of CBG demonstrate high solubility in Jojoba oil, ensuring stable topical formulations with improved skin permeability and bioavailability, suitable for cosmetic and dermatological applications.
✦ Generated by Eureka AI based on patent content.
Abstract
A fatty acid ester of cannabinoid, wherein the fatty acid is an unsaturated acid, with an ester linkage consisting of an aryloxy oxygen directly bonded to an aromatic ring of the cannabinoid and a carbonyl group attached to the fatty acid unsaturated carbon chain.
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