Antimicrobial mixtures

A synergistic mixture of pyrone, tropolone, phenylpropanoid, mono- or sesquiterpene, aromatic acid, and alkanediol compounds addresses the need for universal antimicrobials, offering effective microbial inhibition and cosmetic benefits in various formulations.

WO2026109709A1 Publication Date: 2026-05-28SYMRISE GMBH & CO KG
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Patent Information

Application Number
PCT/EP2025/083822
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-11-22
Filing Date
2025-11-21
Publication Date
2026-05-28

AI Technical Summary

Technical Problem

There is no universal antimicrobial agent that effectively inhibits a wide spectrum of bacteria, yeast, and mold, and existing agents like parabens face safety concerns, necessitating the development of multifunctional, natural compounds for various formulations.

Method used

A mixture comprising at least two of the following compounds: a pyrone derivative, a tropolone derivative, a phenylpropanoid, a mono- or sesquiterpene, an aromatic acid or salt, and an alkanediol, which exhibit synergistic antimicrobial properties against microorganisms like Staphylococcus aureus, Candida albicans, and others, and can be naturally derived or synthetically obtained.

Benefits of technology

The synergistic mixtures provide strong antimicrobial effects, are well-tolerated for skin use, and offer additional cosmetic benefits, making them suitable for pharmaceutical, cosmetic, personal care, animal care, and cleaning formulations.

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Abstract

The present invention relates to a mixture, blend or combination, comprising at least two, preferably at least three, chosen from the following compounds: (A) a pyrone derivative, preferably a 3-hydroxy-4-pyrone, (B) a tropolone derivative, (C) a phenylpropanoid, (D) a mono- or sesquiterpene, or mono- or sesquiterpenoid, (E) an aromatic acid or salt, and (F) an alkanediol, and its use as antimicrobial mixture, blend or combination.
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