Photoacoustic microscopy system and method of forming the same

The integration of a flat optical component in photoacoustic microscopy systems addresses the bulkiness and inefficiency of conventional OR-PAM by enabling compact, portable, and high-resolution imaging suitable for biomedical applications.

WO2026111648A1PCT designated stage Publication Date: 2026-05-28AGENCY FOR SCI TECH & RES
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Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
AGENCY FOR SCI TECH & RES
Filing Date
2025-11-12
Publication Date
2026-05-28

AI Technical Summary

Technical Problem

Conventional optical-resolution photoacoustic microscopy (OR-PAM) systems are bulky, costly, and inefficient due to the integration challenges of acoustic and optical components, which limit their portability and imaging capabilities, particularly in biomedical applications.

Method used

A photoacoustic microscopy system incorporating a flat optical component, such as a metasurface or diffractive lens, to focus light beams and compensate for aberrations caused by acoustic components, allowing for a compact, portable design with extended depth of field and improved imaging resolution.

Benefits of technology

The system achieves high-resolution, compact, and portable imaging by integrating optical and acoustic components efficiently, facilitating easier alignment and access to target tissues for practical biomedical applications.

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Abstract

Various embodiments may relate to a photoacoustic microscopy system. The photoacoustic microscopy system may include a flat optical component configured to focus a light beam emitted by a light source onto a focal point. The photoacoustic microscopy system may additionally include an acoustic receiving device configured to receive acoustic waves from the focal point. The photoacoustic microscopy system may further include an acoustic component configured to direct acoustic waves from the focal point to the acoustic receiving device. The photoacoustic microscopy system may also include an optical and acoustic combiner configured such that the light beam emitted by the light source is redirected within the optical and acoustic combiner towards the focal point, the optical and acoustic combiner further configured to allow the acoustic waves to pass through to the acoustic receiving device.
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