Temperature control unit minimizing electrical noise in in-vitro and in-vivo experiments

The temperature control unit addresses electrical noise interference in experiments by using a water-heated aluminum block chamber with sensors and circulation pumps, ensuring precise temperature regulation and effective electrophysiological recordings.

WO2026127928A1 Publication Date: 2026-06-18KARADENIZ TEKNIK UNIVERSITESI TEKNOLOJI TRANSFERI UYGULAMA & ARASTIRMA MERKEZI MUDURLUGU +1

Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
KARADENIZ TEKNIK UNIVERSITESI TEKNOLOJI TRANSFERI UYGULAMA & ARASTIRMA MERKEZI MUDURLUGU
Filing Date
2025-12-10
Publication Date
2026-06-18

AI Technical Summary

Technical Problem

Existing temperature control systems for in-vitro and in-vivo experiments generate electrical noise that interferes with sensitive electrophysiological recordings, limiting their effectiveness and operability.

Method used

A temperature control unit utilizing an aluminum block chamber and water-heating system, combined with temperature sensors and circulation pumps, maintains precise temperature control with minimal electrical noise by using water-heated aluminum or copper pipes to eliminate direct electrical heating sources.

🎯Benefits of technology

The solution ensures accurate temperature regulation with minimal electrical noise, allowing for uninterrupted and precise electrophysiological recordings without the need for multiple heating systems, reducing costs and space requirements.

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Abstract

The invention relates to a temperature control unit for microscopic examination of living cells and tissues, for precisely heating both the tissue and the fluid supplying the tissue to the desired temperature, and for maintaining a constant body temperature of animals under anesthesia for prolonged periods of time, which produces electrical noise that is either completely absent from electrophysiological recordings or so minimal that it does not affect the recordings.
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