Method and device for manufacturing microbubbles

The described method and device for microbubble manufacturing address contamination issues by using a continuous process with controlled size and yield, resulting in safer and more stable microbubbles suitable for pharmaceutical applications.

WO2026147551A2PCT designated stage Publication Date: 2026-07-09AVVIO MEDICAL INC

Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
AVVIO MEDICAL INC
Filing Date
2025-05-12
Publication Date
2026-07-09

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Abstract

The present disclosure provides a continuous microbubble generating device and system and a method for production of microbubbles. The device can include an inlet port configured to receive a fluid and a gas for the generation of microbubbles. The device can include a manifold comprising a vessel configured to increase the fluid-gas interface in a directed fluid pathway to deliver the fluid and the gas. The device can include an oscillator which is configured to oscillate the vessel for agitating the fluid in order to allow for interaction between the fluid and the gas. The device can further include an outlet port and cooler configured to output the generated microbubbles.
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