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34 results about "Anaesthetic ether" patented technology

The knowledge of ether as an anesthetic spread rapidly. The medical establishment and the public quickly and gratefully accepted the use of ether inhalation for painless surgery. ... Ether is used as a general anesthetic for surgery.

Effervescent granules and methods for their preparation

InactiveUS6649186B1Improve stabilityParticular regionPowder deliveryNervous disorderHYDROMORPHONE HYDROCHLORIDEAlpha adrenergic blockade
Disclosed here are effervescent granules having a controllable rate of effervescence. In some embodiments, the such granules comprise an acidic agent, an alkaline agent, a pharmacologically active agent, hot-melt extrudable binder capable of forming a eutectic mixture with the acidic agent and, optionally, a plasticizer. The effervescent granules are made by a hot-melt extrusion process. The present invention also provides a thermal heat process for preparing a pharmacologically active agent containing effervescent granule. In certain aspects, the granules contain pharmacologically active agents such as narcotics, antidiarrheal agents, antiviral agents, anxiolytic agents, a cholesterol lowering agent, an alpha adrenergic blocking agent, a phenanthrene derivative. By way of example, some of the narcotics that may be included in the granules and in the process of preparing the granules include, by way of example: phenanthrene derivatives (e.g., morphine sulfate), and morphine derivatives (e.g., hydromorphone hydrochloride).
Owner:ETHYPHARM SA

Electrode assembly and method for signaling a monitor

InactiveUS20010031916A1Accurately and quickly placeEasily and economically manufacturedElectrotherapyElectrocardiographyPatient awarenessAdhesive
An electrode assembly adapted to be attached to the skin over selected facial muscle groups picks up signals to be analyzed by an anesthesia adequacy monitor that measures the level of awareness of a living animal, typically a human being. The electrode assembly also includes a stimulator that stimulates a facial nerve to determine the level of paralysis, or neuro muscular block, of the facial muscles. Also disclosed is a method of manufacturing the electrode assembly by printing a pattern of electrically conductive material through a silk-screen or an ink type process onto a flexible layer, and then coating the result with a non-conducting adhesive except at points corresponding to sensing points for the desired muscle groups. Finally, a method for using such sensing and stimulating devices is shown in determining and maintaining an appropriate level of patient awareness, muscle paralysis, and analgesia under anesthesia.
Owner:BENNETT HENRY L +2

Ophthalmic sulcus speculum

InactiveUS7175594B2Problem be addressSurgeryMedical devicesSmall cerebrumSurgery
Devices in accordance with certain embodiments of the present sulcus speculum are designed to be placed into the sulcus of an eye to perform one or more of the following functions: evacuation of fluid, opening of the lids, and application of drugs such as anesthetic or antibiotics. The present devices can include a sponge positioned around (a) an aspiration tube for withdrawing fluid and (b) an arm of a speculum. Other variations of the present devices include those with an aspiration tube for withdrawing fluid, the tube being positioned in a trough defined by an arm of a speculum. Alternatively, the speculum arm can define a passage for holding the aspiration tube. In that alternate embodiment, the portion of the speculum arm defining the passage has openings for passing fluid into the passage so that the aspiration tube in the passage can then remove fluid.
Owner:FOULKES RICHARD B

Hernia mesh-device with incorporated local anesthetic

A mesh-device for surgical repair of a hernia which includes a local anesthetic. The local anesthetic may be either embedded within the mesh, or provided in reservoirs, but is generally evenly distributed across the mesh-device. The local anesthetic is released over a predetermined duration at a predetermined rate.
Owner:CHEFITZ ALLEN B

Carp anaesthesia method

The invention relates to an anesthesia method for carp, which belongs to the technical field of aquiculture. The invention is characterized in that the water of 99.98 to 99.99 weight percentage and the clove oil of 0.01 to 0.02 weight percentage are added in to a container to prepare anesthesia solution, and the carp is put into the container to be anesthetized. After being anesthetized for 2 to 5 minutes, the carp is found lying on side in the solution. And then, the carp is put into the waters of a pond. After 5 to 8 minutes, the crap can swim as usual. The anesthesia method of the invention adopts the clove oil that is commercially available and has good anesthesia effect. The clove oil can be used for soothing toothache of human. So the clove oil is safe to anesthetize the carp and does not affect edibleness. In addition, the clove oil has the advantages of low cost and wide application range.
Owner:FRESHWATER FISHERIES RES CENT OF CHINESE ACAD OF FISHERY SCI

Closed loop drug administration method and apparatus using EEG complexity for control purposes

A closed loop method and apparatus for controlling the administration of an hypnotic drug to a patient. Electroencephalographic (EEG) signal data is obtained from the patient. At least one measure of the complexity of the EEG signal data is derived from the data. The complexity measure may comprise the entropy of the EEG signal data. The EEG signal data complexity measure is used as the feedback signal in a control loop for an anesthetic delivery unit to control hypnotic drug administration to the patient in a manner that provides the desired hypnotic level in the patient. An EEG signal complexity measure obtained from the cerebral activity of the patient can be advantageously used in conjunction with a measure of patient electromyographic (EMG) activity to improve the response time of hypnotic level determination and of the feedback control of drug administration. A pharmacological transfer function may be used, along with pharmacokinetic and pharmacodynamic models.
Owner:GE HEALTHCARE FINLAND

High Volume Carpule System

A high volume carpule system for storing and dispensing a high volume of anesthetic to a patient. A preferred embodiment of the high volume carpule system generally includes a syringe having a modified carpule cavity comprised of an upper ring member and a lower ring member which are linked together by a first side member and a second side member. The side members are oriented in such a manner as to allow a pair of slots through which side portions of a high capacity carpule may extend. A high capacity carpule comprised of a substantially cylindrical shape with an elongated cross-section is disclosed for use with the modified carpule cavity. In an alternate embodiment, a second high capacity carpule design is disclosed for use with conventional, prior art syringes. By using the present invention, a dentist or surgeon may administer a higher volume of anesthetic without having to switch carpules within a syringe.
Owner:MCLELLAND BRYAN W DR

Synergistic combinations of norketamine and opioid analgesics

InactiveUS20080132531A1Rapid introductionExcellent dose-to-effect administration of drugBiocideNervous disorderHeadachesAnalgesic agents
The present invention relates to methods of alleviating pain with the administration of norketamine with a narcotic. More particularly, the invention provides a method of alleviating pain through the administration of a dose of norketamine, which, if administered alone would provide sub-optimal analgesic relief, yet provides analgesic relief when combined with a narcotic. In some embodiments, the combination of norketamine with a narcotic, further allows for the administration of a dose narcotic, which would be sub-optimal if used alone, but provides adequate pain relief in combination with norketamine. The invention relates to self-management of pain on an outpatient basis comprising administering via conventional routes, including transdermal, nasal, rectal, oral, transmucosal, intravenous, intramuscular, and other routes, one or more doses of norketamine / opioid compositions effective to alleviate pain to a subject suffering from pain. Uses of norketamine / opioid compositions would also apply, to treating headaches, drug abuse, mood and anxiety disorders, as well as other, neuropsychiatric disorders, both motoric and cognitive, such as Alzheimer's disease, Parkinson's syndrome, which are thought to be caused by neurodegeneration.
Owner:UNIV OF KENTUCKY RES FOUND

Novel use of ion channel active compound, meperidine, to mediate process of accelerated wound healing

The present invention discloses a method of employing ion channel active compounds to deliver metabolism-enhancing molecules within the cell to promote rapid wound healing. It also develops a delivery kit for meperidine as a local anesthetic and wound healing accelerant for dental surgical use. And meperidine thus serves as a pattern for future design of novel wound healing compounds.
Owner:NICKEL ALFRED A

Throw-away anaesthetic safety injection work drum

This invention relates to a safety injection syringe for discarded anaesthetics characterizing that all components of the syringe are made of plastic, the pinhead draws back into the safety protecting sleeve to be blocked after use and all the components can be discarded at once, it's not necessary to be disinfected and used.
Owner:林辉铭 +1

Nanoparticulated anesthetic composition for topic use

The present invention relates to a nanoparticulated anaesthetic composition for topical use in which at least one local anaesthetic agent is encapsulated in polymeric nanoparticles. The present invention also relates to the use of such polymeric nanoparticles comprising at least one local anaesthetic agent in the preparation of an anaesthetic composition for topical application to the skin or mucosa.
Owner:BIOLAB SANUS FARMACEUTICA LTD +1

Sensory-specific local anesthesia and prolonged duration local anesthesia

Combinations of charged local anesthetics with chemical permeation enhancers have been developed to give long duration block which is selective for sensory block over motor block. The duration of block is greatly prolonged by combining the local anesthetic with a permeation enhancer. The selectivity of sensory over motor block is provided by selecting the concentration of the local anesthetic and the permeation enhancer to provide selective permeability of the sensory and motor neurons to the enhancer.
Owner:MASSACHUSETTS INST OF TECH +1

Sustained release of formulations of local anesthetics

Described herein are sustained release formulations of polymer-coated local anesthetic agents, and methods for using the same to relieve or manage pain, including postsurgical pain.
Owner:EUPRAXIA PHARMA

Wound penetrating hemostatic device impregnated with coagulant, antibiotic and/or anesthetic

InactiveUS8088093B2Highly visible, rapid, effective puncture wound treatmentEfficient use ofNon-adhesive dressingsDiagnosticsEmulsionTamponade
A tampon assembly used for penetration injuries to provide hemostasis and simultaneous broad spectrum antibiotic / anesthetic application. The tampon includes a helically-wound absorbent member impregnated with coagulant, covered with biodegradable or plastic accordion-pleated sheath including a bioluminescent tape outer marker. The device would also contain a measured dose of antibiotic / anesthetic suspension sealed within the confines of the outer sheath. The outer sheath would preferably have a perforated petal-shaped tip to enable wound insertion followed by through passage of the contained wound packing and treatment liquids / emulsions, etc. A radio opaque cotton withdrawal string would attach to the absorbent member at the end facing the wound opening. An insertion stick / plunger is used for tampon deposition within the wound. Manual pressure on the plunger would cause seal rupture and expulsion of the wound packing and treatment through the ruptured tip of the sheath. The tampon device may be of various sizes or shapes to conform to various injuries. It may be used intra-operatively during surgery as well.
Owner:OTTUSO PATRICK +1

Pharmaceutical composition for treating tinea pedis and preparation method thereof

InactiveCN103142564ASymptom improvement of severe itchingLittle side effectsOrganic active ingredientsAntimycoticsGlycerolStearic acid
The invention belongs to the field of medicine, and particularly relates to a pharmaceutical composition for treating tinea pedis and a preparation method thereof. The pharmaceutical composition has the functions of killing preclinical dermatophytes of feet and immediately improving the symptoms of foot pruritus after the pharmaceutical composition added with an anti-pruritus component and a local anesthetic component is used. After use of the According to the pharmaceutical composition, severe pruritus of skin of feet can be relived quickly. According to the technical scheme, the pharmaceutical composition for treating tinea pedis comprises the following raw materials: white oil, emulsifier 60, stearic acid, melaleuca alternifolia, silicone emulsion, ethyparaben, glycerol, purified water and sodium citrate-citric acid pH value buffer system. The pharmaceutical composition has the beneficial effect that the symptom of foot pruritus can be improved immediately after the pharmaceutical composition added with the anti-pruritus component and the local anesthetic component is used.
Owner:邵武市美菰林卫生用品有限公司

Preparation of furane used as inhalation anesthetic

The invention belongs to the technical field of medicine and chemical engineering and in particular relates to a preparation method of isoflurane for inhalation anesthetics. The method solves the problem that the conversion rate is low, the cost is high and the fatalness is high in the prior art; in order to overcome the problems in the prior art, the technical proposal is as follows: the preparation method of isoflurane for inhalation anesthetics comprises the following steps in sequence: (1)reaction: HFE with water content less than 50ppm and lewis acid which are taken as raw materials to take reaction according to the mole number ratio of 1:0.8-3; (2) hydrochloric acid is dropwise added, the mixture stands for layer separation and then oil phase is obtained; (3) the isoflurane product is obtained by neutralizing, washing and rectifying the oil phase. Compared with the prior art, the method has the advantages of high yield, low cost, low hazard and convenient separation and purification.
Owner:中国中化股份有限公司 +1

Propofol-containing fat emulsion

The invention provides a propofol-containing fat emulsion preparation and a method for preparing the same. The propofol-containing fat emulsion preparation comprises: 0.1-2w / v% propofol, 10-20w / v % oily component, and 2-5w / v% emulsifier, the weight of the oily component is about 5-about 200 times that of propofol, and the weight of the emulsifier is about 0.9-200 times that of propofol about 50 times, and the average particle size of the emulsion particles is 180nm or less. The propofol-containing fat emulsion formulation of the present invention can relieve vascular pain occurring during its administration without introducing a local anesthetic such as lidocaine or the like thereinto.
Owner:OTSUKA PHARM FAB INC

Traditional Chinese medicine anaesthetic for local anesthesia

The invention discloses a traditional Chinese medicine anaesthetic for local anesthesia, and relates to the technical field of traditional Chinese medicine. The traditional Chinese medicine anaesthetic is prepared from, by weight, 10-15 parts of Chinese fevervine herbs, 15-30 parts of twigs and leaves of creeping psychotria, 3-10 parts of rhizoma Chuanxiong, 1.5-9 parts of herba asari, 3-9 parts of seeds of roundpod jute, 0.6-0.9 part of acutangular anisodus root, 9-15 parts of false pareira, 9-15 parts of herba cntellae, 4.5-9 parts of corydalis yanhusuo, 3-6 parts of pericarpium zanthoxyli,6-20 parts of white mustard seeds, 3-9 parts of fructus cnidii, 0.3-0.5 part of tangut anisdus radix and 2-6 parts of licorice roots. According to the traditional Chinese medicine anaesthetic for local anesthesia, on the basis of the Chinese traditional medicine principle, all medicines supplement each other, convenience is brought to use, the anesthetic effect is good, people can wake quickly after an operation, pain is relieved, and no toxic or side effect exists.
Owner:THE FIRST AFFILIATED HOSPITAL OF HENAN UNIV OF SCI & TECH

Throw-away anaesthetic safety injection work drum

This invention relates to a safety injection syringe for discarded anaesthetics characterizing that all components of the syringe are made of plastic, the pinhead draws back into the safety protecting sleeve to be blocked after use and all the components can be discarded at once, it's not necessary to be disinfected and used.
Owner:林辉铭 +1

Sterile kit containing silicone gel for stereotaxy

particularly a kit (K), which consists basically of a syringe (1), filled with silicone gel (2) (PMDS), which is supplied with or without a needle (3), and is appropriate for the stereotaxy procedure, showing an excellent radiological contrast and macroscopic locator in a histopathological test. The kit is completely sterile, without any type of negative or harmful interference in the nuclear medicine techniques, radiological localization of wounds and routine histological tests, and is packed in a pre-shaped recipient (4) or in a plastic blister pack (5). The kit may contain other components for use, such as gloves, cotton, gauze and similar (not demonstrated), everything made of disposable material.
Owner:杰瑞多·S·F·维特瑞尔

Preparation capable of relieving untoward effect of anaesthetic and preparation method of preparation

The invention discloses a preparation cable of relieving an untoward effect of an anaesthetic and a preparation method of the preparation, and relates to the technical field of anaesthetics. The preparation is prepared from the following raw materials in parts by weight: 15 to 30 parts of radix aucklandiae, 10 to 20 parts of bran, 5 to 15 parts of semen arecae, 5 to 10 parts of radix et rhizoma rhei, 5 to 10 parts of herba taraxaci extract, 10 to 20 parts of pericarpium citri reticulatae, 5 to 8 parts of fructus jujubae, 10 to 20 parts of radix scutellariae, 5 to 15 parts of rhizoma pinelliae,5 to 10 parts of radix codonopsis, 5 to 10 parts of radix linderae, 10 to 15 parts of cortex magnoliae officinalis, 10 to 15 parts of fructus aurantii immaturus, 20 to 50 parts of honey, 10 to 20 parts of corn starch, 2 to 10 parts of dextrin and 10 to 15 parts of rock candy, wherein the herba taraxaci extract is a herba taraxaci solution which is obtained by filtering out matters of which the molecular weight is greater than 40,000 by a macromolecular filter layer in a filter column. The preparation disclosed by the invention is capable of relieving the untoward effect generated after the use of the anaesthetic, and is capable of relieving symptoms of nausea, emesis, abdominal distension and the like; the added herba taraxaci extract also has anti-bacterial, anti-inflammation and anti-virus effects; the preparation is basically prepared from traditional Chinese medicines, so that the preparation is capable of effectively helping a patient get well as rapidly as possible.
Owner:AFFILIATED YONGCHUAN HOSPITAL OF CHONGQING MEDICAL UNIV

Pharmaceutical composition

InactiveUS20090203733A1Improve actionReduce riskBiocideRespiratory disorderNon domestic8-OH-DPAT
This invention relates to a pharmaceutical composition for mammals and, more particularly, to a pharmaceutical composition which enhances the action of an anaesthetic used in both human and veterinary applications, which, at least partly, reduces the risk of respiratory depression and enhances pulmonary perfusion. The pharmaceutical composition is characterised in that it contains a serotonergic ligand or any pharmacologically acceptable salt or ester thereof which acts on at least one member of the 5-HT family of serotonergic receptors, preferably on one or more of the 5-HTiA, 5-HT4 and 5-HT7 serotonergic receptors. In an example the ligand is the 8-OH-DPAT ligand. The composition can be used in conjunction with or include an anaesthetic, preferably an opioid anaesthetic, to induce a state of anaesthesia in mammals and it can be used to immobilise wile or non-domestic mammals.
Owner:UNIVERSITY OF THE WITWATERSRAND

Motorized syringe for use with two types of dental anesthetic solution-containing cartridges

A motorized syringe for use with two types of dental anesthetic solution-filled cartridges, having a plunger plug in the 1.8 ml cartridge pushed by a push rod by a length required to push a plunger plug in the 1.0 ml cartridge. The syringe includes a cartridge holder for use with 1.0 ml and 1.8 ml cartridges, the push rod having a 1.0 ml position and a 1.8 ml position drawn back from the 1.0 ml position so that push rod movement can end at a common terminal position for both, a sleeve adapted to receive the push rod rear end when pushed back from the common terminal position, and to be not interfered with by the push rod's rear end when it is in the 1.0 ml position, the sleeve being pushed rearward with the push rod's rear end when pushed back to the 1.8 ml position.
Owner:GC SHOWAYAKUHIN CORP

Local anesthetic for tooth extraction as well as preparation method and application of local anesthetic

The invention discloses a local anesthetic for tooth extraction as well as a preparation method and application of the local anesthetic. The local anesthetic for tooth extraction is prepared from thefollowing raw materials in parts by weight: 15-22 parts of aloesin, 6-12 parts of agaricus blazei murill, 5-11 parts of calamine, 10-18 parts of eucalyptus extract, 10-20 parts of cactus juice and 13-28 parts of onion. The local anesthetic provided by the invention is prepared from the aloesin, the agaricus blazei murill, the calamine, the eucalyptus extract, the cactus juice and the onion, and the raw materials are easy to obtain and environmentally friendly; clinical tests prove that the local anesthetic is free from toxic and side effects and does not cause complications, thus being high insafety; the local anesthetic can be used in an operation of tooth extraction, and has a response rate of 99%; the preparation method is simple in process and easy in realization of industrial production, thus being worth of popularization and application.
Owner:吕芳芳

Compound gel preparation for treating radiodermatitis and preparation method thereof

The invention discloses a compound gel preparation for treating radiodermatitis and a preparation method thereof. The compound gel preparation is prepared from the following components in parts by mass: 1-10 parts of superficial anesthesia, 0.1-1 part of glucocorticoid, 0.1-1 part of androgen, 500 parts of an oil phase, 1.4-14 parts of hydrogel matrix, 2-20 parts of a burn anti-infectious agent, 4-300 parts of alcohol and 200-500 parts of water. The compound gel preparation has an excellent prevention and treatment effect for the radiative skin reaction of tumor patients, has the effects of diminishing inflammation, relieving pain, promoting patient wound healing, nourishing skin, repairing skin injury and the like, can be used for remarkably reliving pains of patients with radiodermatitis, is greatly beneficial to continuous radiotherapy for tumor patients. The medicine is an emulsion which has strong skin affinity, is convenient to use and can be easily removed, and can be used for improving the compliance of patients.
Owner:CANCER INST & HOSPITAL CHINESE ACADEMY OF MEDICAL SCI

A device for recovering and discharging anesthesia ether waste gas

The invention discloses a recycling and discharging device for anesthetic diethyl ether waste gas. The device mainly comprises a gas pipe, a sleeve bag, a drug injection connecting pipe, a drug injection port, a joint, a negative pressure pump, a connecting pipe, a collector, a main unit and a digital display panel; the sleeve bag is installed at the bottom of the gas pipe, the top of the gas pipeis connected with the negative pressure pump through the joint, the negative pressure pump is provided with a gas inlet and a gas outlet, the gas outlet is connected with the collector through the connecting pipe, and the digital display panel is installed on the top surface of the collector; the collector comprises a fan, a first filter layer, a second filter layer, a decomposition chamber and acollection chamber, the fan is installed on the inner bottom surface of the collector, the first filter layer is installed in the portion, above the fan, in the collector, the second filter layer isinstalled in the portion, above the first filter layer, in the collector, and the decomposition chamber is formed in the portion, above the second filter layer, in the collector. By means of the recycling and discharging device for the anesthetic diethyl ether waste gas, the problems are solved that the bodies of related personnel of an anesthesia room are damaged by inhalation of the anesthetic waste gas, the pollution is caused by the anesthetic waste gas to the environment, and the waste gas is recycled.
Owner:咸宁市中心医院
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