34 results about "Anaesthetic ether" patented technology

Disclosed here are effervescent granules having a controllable rate of effervescence. In some embodiments, the such granules comprise an acidic agent, an alkaline agent, a pharmacologically active agent, hot-melt extrudable binder capable of forming a eutectic mixture with the acidic agent and, optionally, a plasticizer. The effervescent granules are made by a hot-melt extrusion process. The present invention also provides a thermal heat process for preparing a pharmacologically active agent containing effervescent granule. In certain aspects, the granules contain pharmacologically active agents such as narcotics, antidiarrheal agents, antiviral agents, anxiolytic agents, a cholesterol lowering agent, an alpha adrenergic blocking agent, a phenanthrene derivative. By way of example, some of the narcotics that may be included in the granules and in the process of preparing the granules include, by way of example: phenanthrene derivatives (e.g., morphine sulfate), and morphine derivatives (e.g., hydromorphone hydrochloride).

An electrode assembly adapted to be attached to the skin over selected facial muscle groups picks up signals to be analyzed by an anesthesia adequacy monitor that measures the level of awareness of a living animal, typically a human being. The electrode assembly also includes a stimulator that stimulates a facial nerve to determine the level of paralysis, or neuro muscular block, of the facial muscles. Also disclosed is a method of manufacturing the electrode assembly by printing a pattern of electrically conductive material through a silk-screen or an ink type process onto a flexible layer, and then coating the result with a non-conducting adhesive except at points corresponding to sensing points for the desired muscle groups. Finally, a method for using such sensing and stimulating devices is shown in determining and maintaining an appropriate level of patient awareness, muscle paralysis, and analgesia under anesthesia.

A mesh-device for surgical repair of a hernia which includes a local anesthetic. The local anesthetic may be either embedded within the mesh, or provided in reservoirs, but is generally evenly distributed across the mesh-device. The local anesthetic is released over a predetermined duration at a predetermined rate.

A closed loop method and apparatus for controlling the administration of an hypnotic drug to a patient. Electroencephalographic (EEG) signal data is obtained from the patient. At least one measure of the complexity of the EEG signal data is derived from the data. The complexity measure may comprise the entropy of the EEG signal data. The EEG signal data complexity measure is used as the feedback signal in a control loop for an anesthetic delivery unit to control hypnotic drug administration to the patient in a manner that provides the desired hypnotic level in the patient. An EEG signal complexity measure obtained from the cerebral activity of the patient can be advantageously used in conjunction with a measure of patient electromyographic (EMG) activity to improve the response time of hypnotic level determination and of the feedback control of drug administration. A pharmacological transfer function may be used, along with pharmacokinetic and pharmacodynamic models.

Low volume safe for injection formulations of dantrolene yield significant advantages over the currently approved and marketed dantrolene for MH threatening anesthetic crisis. Once dantrolene can be made immediately available to patients triggered of MH, the anesthesiologist will be able to focus exclusively on the management of the patient's physiologic status in this complex and evolving crisis, not on the laborious and time consuming reconstitution process of the rescue agent. Additionally, a safe for injection low volume formulation of dantrolene can be made widely available to non-anesthesiologist practitioners who have occasion to use dantrolene intravenously in the treatment of other potentially life threatening conditions, including in the field. The low volume, safe for injection formulations of dantrolene, as well as other formulations of dantrolene, have significant advantages over currently used approaches to the prevention and treatment of pumphead, and other neurological, cognitive and motor dysfunction incident to iatrogenically or trauma induced situations of altered blood flow, including those incurred during surgical procedures involving CPB or related procedures, as well as those incurred during non-normothermic episodes caused iatrogenically or by disease.

Devices in accordance with certain embodiments of the present sulcus speculum are designed to be placed into the sulcus of an eye to perform one or more of the following functions: evacuation of fluid, opening of the lids, and application of drugs such as anesthetic or antibiotics. The present devices can include a sponge positioned around (a) an aspiration tube for withdrawing fluid and (b) an arm of a speculum. Other variations of the present devices include those with an aspiration tube for withdrawing fluid, the tube being positioned in a trough defined by an arm of a speculum. Alternatively, the speculum arm can define a passage for holding the aspiration tube. In that alternate embodiment, the portion of the speculum arm defining the passage has openings for passing fluid into the passage so that the aspiration tube in the passage can then remove fluid.

A high volume carpule system for storing and dispensing a high volume of anesthetic to a patient. A preferred embodiment of the high volume carpule system generally includes a syringe having a modified carpule cavity comprised of an upper ring member and a lower ring member which are linked together by a first side member and a second side member. The side members are oriented in such a manner as to allow a pair of slots through which side portions of a high capacity carpule may extend. A high capacity carpule comprised of a substantially cylindrical shape with an elongated cross-section is disclosed for use with the modified carpule cavity. In an alternate embodiment, a second high capacity carpule design is disclosed for use with conventional, prior art syringes. By using the present invention, a dentist or surgeon may administer a higher volume of anesthetic without having to switch carpules within a syringe.

Combinations of charged local anesthetics with chemical permeation enhancers have been developed to give long duration block which is selective for sensory block over motor block. The duration of block is greatly prolonged by combining the local anesthetic with a permeation enhancer. The selectivity of sensory over motor block is provided by selecting the concentration of the local anesthetic and the permeation enhancer to provide selective permeability of the sensory and motor neurons to the enhancer.

A new composition of analgesic bioadhesive healing microspheres in which each microsphere comprises at least:a.—a layer of a polyanion, where the polyanion may be an alginate.b.—a core coated with a polyanion consisting of a triblock copolymer non-ionic surfactant; polexamer 188 or a mixture of them; and a volatile halogenated by-product anaesthetic ether agent of methyl-isopropyl-ether in contact with the internal part of the polyanion layer, which may be sevoflurane.c.—a coating of a polycation in contact with the external part of the polyanion layer, which may be chitosan.

A tampon assembly used for penetration injuries to provide hemostasis and simultaneous broad spectrum antibiotic / anesthetic application. The tampon includes a helically-wound absorbent member impregnated with coagulant, covered with biodegradable or plastic accordion-pleated sheath including a bioluminescent tape outer marker. The device would also contain a measured dose of antibiotic / anesthetic suspension sealed within the confines of the outer sheath. The outer sheath would preferably have a perforated petal-shaped tip to enable wound insertion followed by through passage of the contained wound packing and treatment liquids / emulsions, etc. A radio opaque cotton withdrawal string would attach to the absorbent member at the end facing the wound opening. An insertion stick / plunger is used for tampon deposition within the wound. Manual pressure on the plunger would cause seal rupture and expulsion of the wound packing and treatment through the ruptured tip of the sheath. The tampon device may be of various sizes or shapes to conform to various injuries. It may be used intra-operatively during surgery as well.

The invention provides a propofol-containing fat emulsion preparation and a method for preparing the same. The propofol-containing fat emulsion preparation comprises: 0.1-2w / v% propofol, 10-20w / v % oily component, and 2-5w / v% emulsifier, the weight of the oily component is about 5-about 200 times that of propofol, and the weight of the emulsifier is about 0.9-200 times that of propofol about 50 times, and the average particle size of the emulsion particles is 180nm or less. The propofol-containing fat emulsion formulation of the present invention can relieve vascular pain occurring during its administration without introducing a local anesthetic such as lidocaine or the like thereinto.

The invention discloses a traditional Chinese medicine anaesthetic for local anesthesia, and relates to the technical field of traditional Chinese medicine. The traditional Chinese medicine anaesthetic is prepared from, by weight, 10-15 parts of Chinese fevervine herbs, 15-30 parts of twigs and leaves of creeping psychotria, 3-10 parts of rhizoma Chuanxiong, 1.5-9 parts of herba asari, 3-9 parts of seeds of roundpod jute, 0.6-0.9 part of acutangular anisodus root, 9-15 parts of false pareira, 9-15 parts of herba cntellae, 4.5-9 parts of corydalis yanhusuo, 3-6 parts of pericarpium zanthoxyli,6-20 parts of white mustard seeds, 3-9 parts of fructus cnidii, 0.3-0.5 part of tangut anisdus radix and 2-6 parts of licorice roots. According to the traditional Chinese medicine anaesthetic for local anesthesia, on the basis of the Chinese traditional medicine principle, all medicines supplement each other, convenience is brought to use, the anesthetic effect is good, people can wake quickly after an operation, pain is relieved, and no toxic or side effect exists.

This invention relates to a safety injection syringe for discarded anaesthetics characterizing that all components of the syringe are made of plastic, the pinhead draws back into the safety protecting sleeve to be blocked after use and all the components can be discarded at once, it's not necessary to be disinfected and used.

A motorized syringe for use with two types of dental anesthetic solution-filled cartridges, having a plunger plug in the 1.8 ml cartridge pushed by a push rod by a length required to push a plunger plug in the 1.0 ml cartridge. The syringe includes a cartridge holder for use with 1.0 ml and 1.8 ml cartridges, the push rod having a 1.0 ml position and a 1.8 ml position drawn back from the 1.0 ml position so that push rod movement can end at a common terminal position for both, a sleeve adapted to receive the push rod rear end when pushed back from the common terminal position, and to be not interfered with by the push rod's rear end when it is in the 1.0 ml position, the sleeve being pushed rearward with the push rod's rear end when pushed back to the 1.8 ml position.

The invention discloses a recycling and discharging device for anesthetic diethyl ether waste gas. The device mainly comprises a gas pipe, a sleeve bag, a drug injection connecting pipe, a drug injection port, a joint, a negative pressure pump, a connecting pipe, a collector, a main unit and a digital display panel; the sleeve bag is installed at the bottom of the gas pipe, the top of the gas pipeis connected with the negative pressure pump through the joint, the negative pressure pump is provided with a gas inlet and a gas outlet, the gas outlet is connected with the collector through the connecting pipe, and the digital display panel is installed on the top surface of the collector; the collector comprises a fan, a first filter layer, a second filter layer, a decomposition chamber and acollection chamber, the fan is installed on the inner bottom surface of the collector, the first filter layer is installed in the portion, above the fan, in the collector, the second filter layer isinstalled in the portion, above the first filter layer, in the collector, and the decomposition chamber is formed in the portion, above the second filter layer, in the collector. By means of the recycling and discharging device for the anesthetic diethyl ether waste gas, the problems are solved that the bodies of related personnel of an anesthesia room are damaged by inhalation of the anesthetic waste gas, the pollution is caused by the anesthetic waste gas to the environment, and the waste gas is recycled.