62 results about "Radioresistance" patented technology

The invention discloses a method for preparing a carbon microsphere adsorbent under catalysis of metal salt with a low-temperature hydrothermal method. The method comprises steps as follows: (1) a biomass solution with the concentration being 2wt%-20wt% and a metal salt solution with the concentration being 0.5wt%-2wt% are prepared, then mixed in the mass ratio being (2-5):1 and stirred for 5-10 min, and a reaction solution is obtained; (2) the reaction solution is transferred to a stainless steel reaction kettle, the volume of the reaction solution accounts for 60%-80% of that of the reaction kettle, the reaction solution is heated to 100-160 DEG C at a certain heating speed, reacts at the constant temperature for 8-20 hours and is naturally cooled, separated and dried in vacuum, and hydrothermal carbon microspheres are obtained; (3) the hydrothermal carbon microspheres are calcined and carbonized at the air atmosphere, and the carbon microsphere adsorbent is obtained. The preparation process of the adsorbent is simple, energy consumption is low, the reaction time is shortened to be within 24 hours, and the adsorbent has high adsorption performance for part of positive ions, particularly, uranyl ions, has excellent radioresistance, thermal stability and acid stability and can be widely used for treatment of radioactive wastewater.

The invention discloses an infrared-ultraviolet multicolor detector and a preparation method thereof. The detector comprises a substrate, a multicolor detector table which is formed by orderly growing an AlN buffer layer, an n-type GaN/AlGaN emission layer, an undoped AlGaN barrier layer, an n-type AlGaN window contact layer, an undoped AlGaN absorbing layer, a p-type AlGaN limiting window layer and a p-type GaN contact layer on the substrate; an n-type bottom contact electrode is arranged on the n-type GaN/AlGaN emission layer, an n-type intermediate contact electrode is arranged on the n-type AlGaN window contact layer, and a p-type top contact electrode is arranged on the p-type GaN contact layer. The detector has the advantages of simple structure, easy growth, small volume, being capable of realizing triband response and the like. The detector simplifies the growth process and the processing technology of the device structure, improves the radioresistance capacity of the device, reduces the device volume and lowers the cost. The detector has significant application prospects in the fields of target imaging, alarming, monitoring and the like.

The ball bed piles the fuel element loading and unloading systematic ball examination method and outside installs the type examination system to belong to the ball bed type reactor fuel part examination area of technology. Is by installs has installed the type examination system outside ball pipeline outside, examines two examination coils using the distant field turbulent flow principle the voltage, and carries on the demodulation keleck and phase demodulation processing separately to this two examination coil voltage, obtains contains has had ball information demodulation keleck output voltage UOA and phase demodulation output voltage UOP, then carries on to this voltage UOA and UOP further analyzes and processing, thus judges in the ball pipeline whether has the ball process. This invention also proposed outside installs the type examination system. Uses this invention, the installment and the service does not need to destroy the ball pipeline, guaranteed installs the ex-denning pipeline the integrity and high-pressured gas tightness, reduces the radiation pollution; The sensor coil, the skeleton and other appendices with the radioactive fuel ball contact, are directly low to the entire examination sensor material radioresistance request, are advantageous in enhance the sensor the service life.

The MN/CA IX protein is identified herein as a hypoxia marker. The MN/CA9 gene promoter is characterized, and the location of the HIF-1 binding site within the MN/CA9 promoter is identified. Further, the hypoxia inducibility of the MN/CA9 gene and the uses of such inducibility are disclosed. In one aspect, the invention provides diagnostic/prognostic tools for determining the presence of hypoxia in a tissue in a vertebrate, preferably a human, and for measuring the relative degree of hypoxia in said vertebrate. In another aspect, the invention provides methods using tumor biopsies to predict the radioresistance of a preneoplastic/neoplastic tissue in a vertebrate subject, preferably a human patient, for diseases in which MN/CA IX levels can be used to indicate radiobiologically relevant tumor hypoxia. Such predictive methods can be used as an aid in patient therapy selection.

The invention belongs to a heat preserving waterproof paint for structures such as exterior wall of building, thin roofing, and metal tank housing and so on and fabricating method thereof. Raw material prescription of the heat preserving waterproof paint of the invention based on weight is: 10 parts to 90 parts of water, 10 parts to 90 parts of elastic polyacrylic emulsion, 10 parts to 50 parts of filler, 1 part to 10 parts of propylene glycol, 1 part to 10 parts of thickener, 1 part to 10 parts of rutile type titanium dioxide, 1 part to 3 parts of water- and stain-proofing agent of exterior wall. The paint of the invention is great in heat preservation, waterproofing property, self-cleaning property, filling property, radioresistance and sun protection and has long service life.

The invention discloses a water-based radon-proof interior wall coating, which consists of a component A and a component B. The component A comprises 12 to 20 mass parts of water, 20 to 25 mass parts of pigment, 50 to 60 mass parts of water-based epoxy resin emulsion and 0 to 2 mass parts of water-based color paste; and the component B comprises 20 to 30 mass parts of water-based curing agent, 50 to 60 mass parts of filler and 15 to 25 mass parts of water. The water-based radon-proof interior wall coating can form a dense physical paint film. The paint film has high radioresistance, and can effectively avoid the harm of radon in the wall to human bodies. The coating has the advantages of scrub resistance and stain resistance. Various colors of the coatings can be obtained by adding different color paste and adjusting the using amount of raw materials; and decorative effects such as highlighting, mercerizing, mattifying and the like can be obtained as required to meet different requirements of interior decoration. The coating can be stably stored for a long time so as to reduce the influence of transportation and storage on product quality and ensure the reliability of the product quality.

The present invention relates to a Chinese medicine composition which is made up by utilizing the Chinese medicinal materials of ginseng, licorice root, acanthopanax root, bighead atractylodes rhizome, poria and sehisandra fruit as raw material and adopting the following processes: respectively using ethyl alcohol solution and water to make decoction and extraction of the above-mentioned raw materials, concentrating and drying, etc. Said invented Chinese medicine composition has the main functions of resisting fatigue, resisting radiation and reasisting melanchelia, etc and can be used for improving and curing the diseases of network syndrome, chronic apocamnosis and office syndrome, etc. Said medicine composition has not toxic side effect, and can be made into nutrient agent and health-care food also.

The invention relates to a daily health care product, namely multifunctional nano energy particles. The invention is characterized in that nano materials, natural mineral materials and carbon powder are added to high molecular materials, and the high molecular materials are compounded by a high performance and functionalizing nano technology and are combined with germanium particles and magnetic stripes. Therefore, the obtained nano energy particles are a daily health care product which skillfully combines eight functions of far infrared emission, antibiosis, negative ion release, magnetotherapy, radioresistance, antistatic behavior, air purification and beautification together. The multifunctional nano energy particles can be put and sewed on a pillow, a waist support, a knee shield, a wrist bandage, a mattress and other home textile products, clothes, commodities and the like, and the products can be worn and placed according to different health conditions of individuals combined with human body point therapy in the traditional Chinese medicine, thus having the characteristics of simplicity, convenience, flexibility, high efficiency, safety, wide applicable range of people and the like. The products can achieve the effects on changing microcirculation of a human body, adjusting internal secretion and nervous system, dredging the channels, promoting blood circulation and eliminating blood stasis, diminishing inflammation and alleviating pain, allaying tiredness, improving sleeping, improving the immunity of a human body, beautifying skin, supplementing magnetism, supplementing energy and preventing disease, and have an acupuncture and moxibustion effect without using a needle.

The methods described herein allow for the classification of patients into groups for receiving optimized radiation treatment based on patient specific biomarker signature. The biomarker signature includes markers that have been shown to correlate with TGF-β expression and to be associated with tumor aggressiveness, radioresistance and poor prognosis. The markers play a key role in the epithelial-mesenchymal transition. The methods described herein provide the dual benefits of anti-tumor efficacy plus normal tissue protection when combining TGF-β inhibitors with ionizing radiation to treat cancer patients.

The invention discloses a red stilbene polysaccharide 4 and three effective components of red stilbene polysaccharide 4, and comprises concrete structures of three effective components. The invention discloses a preparation method of red stilbene polysaccharide 4 and three effective components and an application. The disclosed red stilbene polysaccharide 4 and three effective components have the antineoplastic effect, anticoagulation effect, antioxidation effect, antisenescence effect, hpyerglycemic effect, hypolipidemic effect, increased immunity of organism and radioresistance effect.

The present invention discloses a CMOS device of reducing charge sharing effect and a fabrication method thereof. The present invention has an additional isolation for trapping carriers disposed right below an isolation region. the material of the additional isolation region is porous silicon. Since porous silicon is a functional material of spongy structure by electrochemistry anodic oxidizing monocrystalline silicon wafer, there are a large number of microvoids and dangling bonds on the surface layer of the porous silicon. These defects may form defect states in a center of forbidden band of the porous silicon, the defect states may trap carriers so as to cause an increased resistance. And with an increase of density of corrosion current, porosity increases, and defects in the porous silicon increase. The present invention can reduce the charge sharing effect due to heavy ions by using a feature that the defect states in the porous silicon trap carriers, the formation of a shallow trench isolation (STI) region and a isolation region underneath only needs one time photolithography, and the process is simple, so that radioresistance performance of an integrated circuit may be greatly increased.

The invention relates to the application of fusion protein GST-PTD-SOD under the radiative condition, wherein, the GST-PTD-SOD is the fusion protein GST-PTD-SOD in which glutathione s-transferase (GST) and TAT protein transduction domain are connected with superoxide dismutase, and a substance containing the GST-PTD-SOD is applied in radiation resisting. The fusion protein GST-PTD-SOD can increase the activity of the SOD in cells; because the transmembrane efficiencies of the fusion protein GST-PTD-SOD are different in various cells and the demand degrees of various cells are different in terms of free radials, the fusion protein GST-PTD-SOD has different protection and reparation effects on various cells, and relatively speaking, the fusion protein GST-PTD-SOD has a better protection and reparation effect on some normal cells than on cancer cells. The fusion protein GST-PTD-SOD can be used as the effective component of anti-radiation injury drugs and has the efficacies of increasing the anti-radiation ability of cells, increasing the differences of the radiation sensitivity of various cells and repairing radiation-injured cells.

The invention provides a tea polyphenols micro-pill that is prepared from tea polyphenols and pharmaceutical adjuvant, which is characterized in that the pharmaceutical adjuvant is an excipient and a bonding agent. The tea polyphenol micro-pill comprises (by weight percentage) that: tea polyphenols 20-80 percent, the excipient 15-79 percent and the bonding agent 1-5 percent. The tea polyphenols micro-pill can be made into sustained-release preparation or enteric-coated preparation. The pharmacological experiment indicates that the tea polyphenols micro-pill of the invention has good effect on radioresistance, anti-aging, etc.

The invention relates to a method for repairing a thorium (IV)-polluted water body by employing a facultative marine fungi living body. The method comprises the following steps: adding a facultative marine fungi (i) Fusariumsp.#ZZF51 living body serving as a material to a polluted water body containing thorium (IV); fishing out the facultative marine fungi living body; and carrying out centralized treatment after a period of time, wherein the fungi material has strong salt tolerance and radioresistance, and strong thorium (IV) enriching ability; the removal rate can be up to 70-80% 2-8 hours after the facultative marine fungi living body is added; and fungal active mycelium floats on the surface of the water body, and can be easily fished out and subjected to centralized treatment. The method has the economic and technical advantages of being simple and convenient to operate and manage, low in cost, high in remediation efficiency, friendly to environment, free of secondary pollution and the like, and is suitable for after-treatment of various thorium-polluted water bodies from thorium mines and hydrometallurgical plants, as well as various spent ore and tailing leaching liquid.

The invention is a vacuum microelectronic acceleration sensor, including active polar plate, insulating layer, vacuum microcavity, top and bottom anode plates and signal detecting circuit. The active polar plate is hollow, the top and bottom anode plates interlink with the active polar plate to form a vacuum cavity in the middle. Where the active polar plate has basal plate which supports a mass block in the middle by cantilever beam, the top and bottom surface of the mass block are distributed with silicon micro field emission cathode cone array and overload protective rings, there is output electrode of the active polar plate on the basal plate, there is another output electrode on the anode plate. The above electrodes are connected with the signal detecting circuit by lines. Its advantages of radioresistance, good temperature stability, fast response, high sensitivity, high resolution, etc, and has extremely wide use.

The invention discloses environment-friendly anti-radiation interior wall latex paint. With an organosilicon modified acrylate emulsion as a main material, the paint has good flexibility, high-low temperature resistance, water resistance and weather fastness and low surface energy; under the mutual synergistic effect of modified hollow glass beads, jade powder and a polygonatum odoratum and grape leaf mixed extraction solution, the radioresistance, the reflective thermal insulation and the ultraviolet absorption ability are improved; a non-ionic emulsifier is intercalated in an ionic emulsifier, so that the distance between ion bonds of a reactive emulsifier on the surfaces of latex particles is increased, electrostatic tension of latex particle surfaces is reduced through electrostatic shielding of the non-ionic emulsifier, distribution of the reactive emulsifier on latex particles is increased, and accordingly, the latex paint has higher stability and good surface tension; by means of shell powder, the latex paint has fine texture and a full paint film, precipitation and good brushing property are avoided, and porosity is favorable for adsorbing harmful substances such as formaldehyde, metal ions and the like in air; with the deionized water as a solvent, the latex paint is safe, environment-friendly, high in solid content, low in content of VOC, high in adhesion force and excellent in water resistance, and the thickness of the paint film can be increased.

The invention relates to an In Gan/Si dual-junction solar cell which comprises an n-Si lining. An A1N nucleation layer, a GaN damping layer, an n-InxGa1-x layer, a p-InxGa1-xN layer and a positive electrode are sequentially arranged on the solar cell. The solar cell is characterized in that a p-Si layer is arranged between the nucleation layer and the lining and forms a Si-lining cell together with the n-Si lining, a semi-transparent current expansion layer is evaporated on the p-InxGa1-xN layer, and a negative electrode is evaporated below the n-Si lining. Since the p-Si layer is formed between the A1N nucleation layer and the n-Si lining and forms the Si-lining cell together with the n-Si lining, the solar cell is easy to manufacture and high in total conversion efficiency. By the aid of the evaporated semi-transparent current expansion layer, the solar cell is strong in radioresistance capacity and long in service life. Since the negative electrode is evaporated below the n-Si lining, process is simplified, cost is lowered, the solar cell can be used as a reflecting mirror, and the total conversion efficiency is improved.

The invention discloses a fire detection device and method under the nuclear power station extreme environment condition. The fire detection device and method are applicable to video processing underthe fireproof region intrinsic special environment of a nuclear power plant, and a fire intelligent recognition model is formed. The fire detection device comprises a table trolley which comprises a display screen for displaying various data; a processing mainframe is in data connection with the display screen, and a software part and multiple driving programs are installed inside the processing mainframe; a power module supplies power to the table trolley; a data interface board is used for wired and wireless data connection between the interior and the exterior of the table trolley; a video,audio an remote wireless alarm device is used for supplying alarm information to an emergency system or other designated interfaces or providing images or short videos as needed; a plurality of radioresistance camera devices are distributed inside the fireproof region, and each radioresistance camera device comprises a support and a pan-tilt arranged on the support; a camera is arranged on the pan-tilt and has the heating function. The fire detection device is high in interference resistance, good in environmental suitability and stable in working performance.

The invention discloses a total nutrient multifunctional compound health care product, which is prepared by compounding black tea powder, sea-buckthorn powder, placenta hominis powder and bee pollen, wherein the compound proportion of ingredients, by weight, is set as follows: 20% - 80% of the black tea powder, 17% - 80% of the sea-buckthorn powder, 1% - 15% of the placenta hominis and 2% - 20% of the bee pollen. According to the health care product, the ingredient usage amount of the health care product is less than the individual usage amount of each ingredient, comprehensive effects exceedand enhance those of ingredients which are used individually, and application scope is expanded. The health care product has obvious health care functions including digestive systems, immunity, antibiosis and antiphlogosis, antioxidation, radioresistance, delaying senescence, weight losing, beautifying and the like.

The invention belongs to the field of radiotherapeutic sensitization drugs and particularly discloses novel use of a cathepsin L inhibitor in the preparation of a radiotherapeutic sensitization drug. The invention firstly proves that the activity of cathepsin L is related to the radioresistant mechanism of glioma stem cells and is an important regulating factor in the mechanism for restoring and periodically regulating the damage to the DNA of the glioma stem cells caused by radiation, and the cathepsin L inhibitor can effectively overcome the phenomenon of radioresistance of tumor cells, so that an experimental basis is provided for proving that the cathepsin L is a new acting target position in the radiotherapy of glioma. The invention simultaneously provides the novel use of the cathepsin L inhibitor in the preparation of the radiotherapeutic sensitization drug, wherein the cathepsin L inhibitor is selected from Z-phenylalanine-tyrosine tert-butyl-nitrous ketone or cathepsin siRNA.

The invention belongs to the field of biotechnology and medical technology, and provides an application of self-designed RNA nucleic acid in enhancing the sensitivity of radiation-resistant lung cancer cells to radiation therapy. The RNA nucleic acid provided by the invention can significantly increase the sensitivity of radiation-resistant lung adenocarcinoma cells to radiation therapy by regulating the STAT3 signal, thereby providing a new idea for the treatment of radiation-resistant lung adenocarcinoma.

The invention discloses natural plant ganoderma anti-aging skin cream, and belongs to the technical field of preparation and production of modern traditional Chinese medicine cosmetics. The natural plant ganoderma anti-aging skin cream is composed of a ganoderma pine pollen shikonin extract, ganoderma radix codonopsis pollen mineral elements and ganoderma astragalus sinicus pollen natural anti-aging skin cream. The ganoderma, pollen, natural plants and mineral elements are added to supplement natural elements of a human body, the element balance in the body is increased, the ability of body toresist diseases is improved, the cell vitality is enhanced, an internal illness is treated by external treatment, free radicals in the body are effectively eliminated, toxin filtering, toxin suctionand heavy metal antagonism are achieved, cancer prevention and radioresistance are achieved, skin beauty, skin care and senility resisting are achieved, body-building of youth is maintained.

The invention discloses a moderate liquid cosmetic with effects of radioresistance and skin moisture improvement, which comprises the following raw materials based on the mass fraction of 100%: 3% to 10% of oat extracting solution, 6% to 10% of NMF-50 (Natural Moisturizing Factor-50), 5% to 18% of sheep placenta polypeptide extracting solution, 5% to 6% of 1,3-butanediol, 0.5% to 1% of allantoin, 0.05% to 0.1% of EDTA (Ethylene Diamine Tetraacetic Acid) disodium, 54.35% to 80.05% of water and 0.4% to 0.6% of preservative. The moderate liquid cosmetic with effects of radioresistance and skin moisture improvement provided by the invention is capable of solving the problems that the skin is dehydrated and dried and liable to be allergic and aged caused by outside thermal radiation, electromagnetic radiation, facing to computers for a long time, air pollution or self-aging, so that the moderate liquid cosmetic plays a role in preventing radiation, supplementing water and maintaining and repairing the skin and has good market value.

Disclosed are increased expression of ERp57, ERp57-STAT3 complex, and ERp57-STAT3-Mcl-1 in laryngeal cancer, especially in radioresistant laryngeal cancer and their regulations on radioresistance of laryngeal cancer. As such, the efficacy of radiotherapy can be enhanced by diagnosing prognosis in laryngeal cancer and radioresistance of laryngeal cancer. Furthermore, provided are a method of screening a therapeutic agent for laryngeal cancer including selecting a candidate drug that inhibits the expression of ERp57 or inactivates ERp57, and a therapeutic method for inhibiting or treating laryngeal cancer or radioresistant laryngeal cancer, thereby being useful in the treatment of laryngeal cancer.

The invention relates to a radioresistant lung cancer whole-cell vaccine, and a preparation method and application thereof, and particularly establishes a radioresistant lung cancer cell strain with obviously higher radioresistance, of which the collection number is CCTCC No.C201537. The animal experiment proves that the lung cancer whole-cell vaccine prepared by using the cell strain has the obvious actions on inhibiting mouse lung cancer tumors from growth, promoting transplantation tumor apoptosis and lowering the expression of the transplantation tumor immunologic escape PDL-1 protein; and when being combined with CpG ODN, the lung cancer whole-cell vaccine has more obvious actions on tumor inhibition, and part of mouse tumors completely disappear, thereby obtaining permanent specific antitumor effects. The invention provides a new idea and method for treating lung cancers and preventing postoperative metastasis and relapse.

The invention discloses a preparation method of an extract product of Nannochloropsis sp., and a radioresistance application. The method comprises the following steps: wall breaking of algae powder, after degreasing, algal oil and algal residues are obtained, the algal residues are extracted with ethanol, an alcohol extract and residues are obtained, residues are extracted with water, and a water extract is obtained. The water extract of microalgae has obvious protection effects for hematopoiesis function of mice with radiation damage.