Endoscopic annular tissue closure enhancement implant

Abstract

The present invention discloses an endoscopic annular tissue closure enhancement implant device, comprising an end cap mounted at the end of an endoscope, the end cap being provided with an instrument cavity for accommodating an instrument to be implanted into the annular tissue, the instrument cavity having a proximal end and a distal end, an operating port being provided at the proximal end of the instrument cavity, a release port being provided at the distal end of the instrument cavity, and a locking portion being provided within the instrument cavity, which can be moved relative to the instrument cavity by an external device to have a locked position and an unlocked position. The implant device is delivered into the annular tissue through the endoscope, and the external device moves from the proximal end to the distal end of the instrument cavity through the operating port to release the instrument at the release port, thereby implanting the instrument into the annular tissue without requiring laparotomy or laparoscopic surgery, resulting in minimal trauma, and the ability to implant different numbers and types of instruments as needed, making the device suitable for a variety of annular tissues.

Description

Technical Field

[0001] The present invention relates to the technical field of annular tissue implantation equipment, and in particular to an implantation device for enhancing the closure function of annular tissue under endoscopy. Background Art

[0002] Circular tissue is typically found along the walls of certain lumens in humans and animals, playing a crucial role in controlling the normal flow of luminal contents. Sphincters are a type of circular tissue found in the human body, including those found in the digestive tract and urinary system. Contracting, they close the lumen, while relaxing opens it, and they are usually closed. The lower esophageal sphincter at the esophagus effectively prevents the reflux of gastric contents into the esophagus. The pyloric sphincter at the stomach outlet limits the amount of food expelled with each gastric peristalsis and prevents the duodenal contents from flowing back into the stomach. The ileocecal sphincter at the junction of the terminal ileum and cecum prevents the ileal contents from draining into the cecum, preventing them from entering the large intestine too quickly. This prolongs the residence time of chyme in the small intestine, facilitates complete digestion and absorption of small intestinal contents, and prevents the reflux of large intestinal contents into the ileum. Weakened or lost sphincter function due to various reasons can cause serious clinical adverse consequences, such as weakened lower esophageal sphincter function causing reflux esophagitis and Barrett's esophagus; relaxation of the pyloric sphincter causing bile reflux gastritis; damage to the urethral sphincter causing urinary incontinence; and damage to the anal sphincter causing fecal incontinence.

[0003] After years of research and development abroad, related products have emerged to treat weakened or ineffective lower esophageal sphincter function. For example, U.S. Patent No. 7,695,427B2, entitled "Device for Treating Esophageal Lumens," discloses a device for treating gastroesophageal reflux disease. The device comprises a magnetic bead chain, connected at both ends to form a closed loop. This device is placed around the outside of the patient's lower esophageal lumen via minimally invasive laparoscopic surgery. Its main disadvantages are that it cannot be minimally invasively implanted, requiring open or laparoscopic surgery. This device is highly traumatic to the patient, resulting in slow postoperative recovery and the risk of intraoperative and postoperative complications. Furthermore, it is only suitable for treating gastric reflux disease and cannot treat other conditions involving weakened or ineffective annular tissue closure.

[0004] The purpose of the present invention is to provide an endoscopic annular tissue closure function enhancement implant device to solve the problem that open surgery or laparoscopic surgery is required during implantation and that it is not applicable to the closure function treatment of various annular tissues. Summary of the Invention

[0005] In view of the above analysis, the present invention proposes an endoscopic annular tissue closure enhancement implant device to address the deficiencies of the prior art.

[0006] The present invention is mainly achieved through the following technical solutions:

[0007] An endoscopic annular tissue closure enhancement implantation device includes a tip cap installed at the tip of an endoscope, the tip cap is provided with an instrument cavity for cooperating with and accommodating an instrument to be implanted into the annular tissue, the instrument cavity has a proximal end and a distal end, the proximal end of the instrument cavity is provided with an operating port, the distal end of the instrument cavity is provided with a release port, and a locking portion is provided in the instrument cavity, which can be pushed by an external device to move relative to the instrument cavity and have a locked position and an unlocked position.

[0008] Furthermore, the instrument is interference-fitted in the instrument cavity, and the tip cap is a non-magnetic tip cap.

[0009] Furthermore, the tip cap includes a mounting sleeve and a release sleeve connected to each other, the mounting sleeve is arranged on the tip of the endoscope, the instrument cavity is arranged on the release sleeve, and the release sleeve is located on the inner wall or outer wall of the mounting sleeve.

[0010] Furthermore, it also includes a release component, the release component is provided with a pushing portion, and the pushing portion is cooperated and arranged in the instrument cavity.

[0011] Furthermore, the release sleeve is located on the inner side wall of the mounting sleeve, the release component is a push rod, the upper end of the push rod is a push portion, and the push portion passes through the endoscope and is cooperated in the instrument cavity.

[0012] Furthermore, the release sleeve is located on the outer side wall of the mounting sleeve, the release assembly is a pull rope assembly, the pull rope assembly includes a pull rope, the pull rope has a free end and a pushing portion, the pull rope is movably arranged on the release sleeve, and the pushing portion is located in the instrument cavity.

[0013] Furthermore, the pull rope assembly further includes a pushing member, and the pushing member is cooperatively arranged on the pushing portion.

[0014] Furthermore, at least one group of rope holes are relatively provided on the side walls of the instrument cavity, the middle portion of the pull rope is arranged in the instrument cavity, and both ends of the pull rope respectively pass through the rope holes and extend to the outside.

[0015] Furthermore, it also includes a magnet, which includes an implantable shell and a magnetic member. The implantable shell is arranged in the annular tissue, and the magnetic member is movably arranged in the implantable shell.

[0016] Furthermore, the magnetic member is a magnetic bead, the implantable shell has a spherical cavity, and the inner diameter of the implantable shell is larger than the outer diameter of the magnetic bead.

[0017] Compared with the prior art, the beneficial effects of the technical solution of the present invention are as follows:

[0018] The endoscopic annular tissue closure enhancement implant device provided by the present invention is used to deliver the implant device into the annular tissue through an endoscope, and an external device moves from the proximal end to the distal end of the instrument cavity through an operating port to release the instrument at a release port, thereby implanting the instrument into the annular tissue without the need for open surgery or laparoscopic surgery, resulting in less trauma. Different quantities and types of instruments can be implanted as needed, and the device is suitable for a variety of annular tissues. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0020] Figure 1 2 is a schematic structural diagram of Example 1 of the implant device for enhancing the closure function of annular tissue under endoscopy provided by the present invention;

[0021] Figure 2 yes Figure 1 Stereoscopic view of the endoscope mounted and the magnet placed;

[0022] Figure 3 yes Figure 2 A stereogram from another perspective;

[0023] Figure 4 yes Figure 2 Longitudinal cross-sectional view before the magnet is released;

[0024] Figure 5 yes Figure 1 Schematic diagram of the decomposition;

[0025] Figure 6 This is a stereoscopic diagram of Example 2 provided by the present invention installed on an endoscope and having a magnet placed thereon;

[0026] Figure 7 yes Figure 6 Longitudinal cross-sectional view before the magnet is released;

[0027] Figure 8 This is a schematic diagram comparing the cross sections before and after three magnets are placed in an unclosed annular tissue.

[0028] The reference numerals are as follows:

[0029] 1. Endoscope, 2. Tip cap, 21. Mounting sleeve, 21a. Limiting portion, 22. Release sleeve, 3. Annular tissue, 4. Magnet, 41. Implantable shell, 411. First shell, 412. Second shell, 42. Magnetic member, 5. Instrument cavity, 5a. Proximal end, 5b. Distal end, 6. Release port, 7. Release assembly, 71. Pull rope, 71a. Free end, 72. Push member. DETAILED DESCRIPTION

[0030] In order to enable those skilled in the art to better understand the present invention, thereby making a clearer definition of the scope of protection of the present invention, the present invention is described in detail below with respect to certain specific embodiments of the present invention. It should be noted that the following are only certain specific embodiments of the present invention, which are only part of the embodiments of the present invention, wherein the specific and direct description of the relevant structures is only for the convenience of understanding the present invention, and each specific feature does not naturally and directly limit the scope of implementation of the present invention. Conventional selections and replacements made by those skilled in the art under the guidance of the present invention should all be deemed to be within the scope of protection of the present invention.

[0031] The present invention will be further described below with reference to the accompanying drawings and specific embodiments.

[0032] An endoscopic annular tissue closure enhancement implant device includes an end cap 2 mounted at the distal end of an endoscope 1. The end cap 2 is provided with an instrument cavity 5 for accommodating an instrument to be implanted into annular tissue 3. The instrument cavity 5 has a proximal end 5a and a distal end 5b. The proximal end of the instrument cavity 5 is provided with an operating port, and the distal end 5b of the instrument cavity 5 is provided with a release port 6. A locking portion is provided within the instrument cavity 5, which can be moved relative to the instrument cavity 5 by an external device and has a locked position and an unlocked position. The distal end 5b herein refers to the end near the distal end of the endoscope 1, and the proximal end 5a refers to the end away from the distal end of the endoscope 1. The locked position of the locking portion is used to lock the instrument, and the unlocked position of the locking portion is used to unlock the instrument so that the instrument is released at the release port 6. The external device moves from the proximal end 5a to the distal end 5b of the instrument cavity 5 through the operating port to position the locking portion in the unlocked position, thereby facilitating the release of the instrument at the release port 6.

[0033] Specifically, the device has an interference fit within the device cavity 5, and the tip cap 2 is a non-magnetic tip cap. The interference fit between the device and the device cavity 5 forms a locking portion, which locks the device in the absence of external force. When driven by an external force, the device can withstand a certain resistance and move along the device cavity 5 until it leaves the device cavity 5, unlocking it. This simple structure prevents the device from falling out of the device cavity 5. The transparent tip cap 2 facilitates endoscope 1 inspection of the device implantation.

[0034] The locking part can also be set in the form of a spring sheet, which has a free end and a fixed end. The fixed end of the spring sheet is set on the inner wall of the instrument cavity 5. The free end of the spring sheet closes the release port 6 to lock the instrument, preventing the instrument from falling from the instrument cavity 5. When the spring sheet is driven by external force, the free end of the spring sheet is pushed open to open the release port 6 to unlock the instrument, which has high reliability.

[0035] Preferably, the tip cap 2 includes a mounting sleeve 21 and a release sleeve 22, which are connected to each other. The mounting sleeve 21 is mounted on the tip of the endoscope 1, and the instrument cavity 5 is provided on the release sleeve 22. The release sleeve 22 is located on the inner or outer wall of the mounting sleeve 21. Both ends of the mounting sleeve 21 and the release sleeve 22 are open, so that the mounting sleeve 21 can be mounted on the endoscope 1 without blocking the lens. The two ends of the release sleeve 22 respectively form an operation port and a release port 6.

[0036] Specifically, a stopper 21a is provided on the inner wall of the mounting sleeve 21. The stopper 21a cooperates with the tip of the endoscope 1 to prevent the tip cap 2 from shifting during the movement of the endoscope 1. The stopper 21a is a stopper ridge to prevent the lens from being blocked.

[0037] Preferably, it further comprises a release assembly 7 , on which a pushing portion is provided, which is cooperatedly arranged in the instrument cavity 5 .

[0038] Preferably, release sleeve 22 is located on the inner sidewall of mounting sleeve 21. Release assembly 7 is a push rod, the upper end of which is a push portion. The push portion passes through endoscope 1 and is fitted into instrument cavity 5. Because tip cap 2 is in an inner 8 shape, the push rod does not contact annular tissue 3 when endoscope 1 is placed into annular tissue 3. Movement of the push rod minimizes irritation to the annular tissue 3, thus reducing patient discomfort during device implantation.

[0039] Specifically, the push rod can be a tube, rod, or other auxiliary device, and the endoscope 1 is provided with an instrument channel for the push rod or other auxiliary device to operate. When the release component 7 is a push rod, the release sleeve 22 can also be disposed on the outer wall of the mounting sleeve 21, so that the tip cap 2 forms an outer 8 shape. The outer wall of the endoscope 1 is provided with an instrument channel to facilitate the insertion of the push rod.

[0040] Preferably, release sleeve 22 is located on the outer wall of mounting sleeve 21. Release assembly 7 is a pull cord assembly comprising a pull cord 71 having a free end 71a and a push portion. Pull cord 71 is movably mounted on release sleeve 22, with the push portion located within instrument lumen 5. When free end 71a of pull cord 71 is pulled away from release opening 6, the push portion pushes the instrument toward release opening 6. Tip cap 2 is configured in an external 8-shape. When endoscope 1 is placed into annular tissue 3, tip cap 2 does not obstruct endoscope 1. The space in instrument lumen 5 and the size of the instrument can be adjusted over a wide range. Furthermore, release assembly 7 does not need to pass through endoscope 1, thus not affecting the instrument channel of endoscope 1 used by other operating instruments.

[0041] Specifically, the pull cord assembly further includes a pusher 72, which is cooperatively arranged on the push portion. The pusher 72 is a release bead connected in series to the pull cord 71. The pusher 72 can also be columnar.

[0042] When the release component 7 is a pull rope or bead structure, the release sleeve 22 can also be set on the inner side wall of the installation sleeve 21, so that the tip cap 2 is in an inner 8 shape.

[0043] Preferably, at least one set of rope holes is provided on the side walls of the instrument cavity 5. The middle portion of the pull rope 71 is provided in the instrument cavity 5. The two ends of the pull rope 71 extend through the rope holes to the outside. Pulling the pull rope 71 at both ends simultaneously can quickly release the instrument, saving operation time. The instrument and the inner wall of the instrument cavity 5 are interference-fitted or interference-fitted through the pull rope 71. When the pull rope 71 is interference-fitted, the pull rope 71 is clamped between the instrument and the inner wall of the instrument cavity 5, so that the instrument is locked when there is no external force. When driven by an external force, the instrument is moved along the instrument cavity 5 by resistance until it separates from the pull rope 71 to unlock and escape from the release port 6. Therefore, the interference fit needs to be provided close to the release port 6 to prevent the instrument from slipping out of the instrument cavity 5.

[0044] In some embodiments, two groups of rope holes are provided at intervals, one near the proximal end 5a and the other near the distal end 5b. When the pull rope 71 is stretched, only the portion of the pull rope 71 outside the tip cap 2 rubs against the annular tissue 3, thereby reducing the stimulation area of ​​the annular tissue 3.

[0045] In other embodiments, the pull rope 71 may also be configured such that one end passes through the side wall of the tip cap 2 to become a free end, and the other end is fixed to the tip cap 2 , which causes less irritation to the annular tissue 3 .

[0046] Specifically, one end of the tip cap 2 close to the proximal end 5 a is opened to form an operation port to reduce the resistance of pulling the pull rope 71 .

[0047] As one of the implementation forms of the instrument, preferably, it further includes a magnet 4 , which includes an implantable shell 41 and a magnetic member 42 . The implantable shell 41 is arranged in the annular tissue 3 , and the magnetic member 42 is movably arranged in the implantable shell 41 .

[0048] The magnetic member 42 is free to move within the implantable housing 41. By placing multiple magnets 4 within the annular tissue 3, the magnetic members 42 within different implantable housings 41 automatically adjust their magnetic poles, causing the multiple magnets 4 to attract each other, thereby increasing the closure of the annular tissue 3. The magnetic member 42 is encased in the implantable housing 41. Because the implantable housing 41 is biocompatible, direct contact between the magnetic member 42 and the annular tissue 3 is avoided. By providing different numbers of magnets 4 that are attracted to each other, the closure force of the annular tissue 3 can be adjusted, allowing therapists to freely choose according to actual conditions, making the magnet 4 applicable to a variety of annular tissue 3 closure treatments.

[0049] Specifically, magnetic member 42 is a magnetic bead, and implantable housing 41 has a spherical cavity. The inner diameter of implantable housing 41 is larger than the outer diameter of the magnetic bead. This allows the magnetic bead to roll freely along the spherical cavity. Because the magnetic bead has a certain size and strong attraction, it is not necessary to place a large number of them. Furthermore, they are located within implantable housing 41 and are not easily displaced after being implanted into annular tissue 3.

[0050] Preferably, the implantable housing 41 includes a first housing 411 and a second housing 412 connected to each other. The first housing 411 is provided with a first receiving groove, and the second housing 412 is provided with a second receiving groove. When the first housing 411 and the second housing 412 are spliced ​​together, the first receiving groove and the second receiving groove are combined to form a receiving cavity for accommodating the magnetic component 42. This facilitates the movable installation of the magnetic component 42.

[0051] Specifically, the implantable housing 41 is a spherical shell structure. The implantable housing 41 is made of an implantable metal material or an implantable non-metallic material. It has the advantages of being lightweight and having good biocompatibility.

[0052] Preferably, the implantable metal material is one of stainless steel, titanium alloy, and nickel-titanium alloy. The implantable non-metallic material is one of polyoxymethylene and polyetheretherketone. This can meet the different needs of users.

[0053] Specifically, the first shell 411 and the second shell 412 are connected by threads, snaps, adhesives or welding, which facilitates installation and disassembly.

[0054] like Figure 8 As shown, at least two magnets 4 are implanted once or multiple times into corresponding locations on the outer wall of the annular tissue 3 through an endoscope 1. Different magnets 4 magnetically attract and cooperate with each other to adjust the closure capacity of the annular tissue 3, with minimal trauma. Depending on the actual closure capacity of the annular tissue 3, different numbers of magnets 4 can be placed on the outer wall of the annular tissue 3, typically 2-6. Different numbers of magnets 4 result in different closure forces on the annular tissue 3, allowing therapists to freely select according to actual circumstances. The treatment is applicable to a variety of annular tissue 3 closure function treatments to meet the treatment needs of different patients.

[0055] Example 1

[0056] like Figure 1-5 As shown, an implantable device for enhancing the closure function of annular tissue under endoscopy comprises an end cap 2 and a push rod. The end cap 2 comprises a mounting sleeve 21 and a release sleeve 22 connected thereto. The mounting sleeve 21 is mounted on the end portion of the endoscope 1. The mounting sleeve 21 is provided with a mounting channel extending vertically therethrough. The inner wall of the mounting channel is provided with a limiting ridge that cooperates with and abuts against the end portion of the endoscope 1. The endoscope 1 is provided with an instrument channel. The release sleeve 22 is provided on the inner side wall of the mounting channel and forms an inner 8 shape with the mounting sleeve 21. The release sleeve 22 is provided with an instrument cavity 5 extending vertically therethrough. The instrument cavity 5 of the release sleeve 22 is located directly above the instrument channel. The instrument cavity 5 accommodates a magnet 4 disposed near a release port 6 in an interference fit. The instrument channel is provided with a push rod that is inserted upwardly into the mounting channel and the instrument cavity 5 in sequence. The length of the push rod is greater than the sum of the lengths of the endoscope 1 and the instrument cavity 5.

[0057] Before release, the magnet 4 is located in the instrument cavity 5 inside the tip cap 2, and the magnet 4 is located directly above the instrument channel of the endoscope 1. The push rod is located in the instrument channel of the endoscope 1. When the push rod is pushed upward, the push rod will release the magnet 4 outward, allowing the magnet 4 to enter the annular tissue 3.

[0058] Example 2

[0059] like Figure 6-7 As shown, an implantable device for enhancing the closure function of annular tissue under endoscopy comprises an end cap 2, a drawstring 71, and a release bead. The end cap 2 comprises a connected mounting sleeve 21 and a release sleeve 22. The mounting sleeve 21 is mounted on the end of an endoscope 1 and defines a vertically extending mounting channel. The inner wall of the mounting channel is provided with an annular retaining ridge that engages and abuts against the end of the endoscope 1. The release sleeve 22 is disposed on the outer wall of the mounting sleeve 21, forming an outer "8" shape with the mounting sleeve 21. An instrument cavity 5 is provided in the release sleeve 22, which passes through the instrument cavity 5 from top to bottom. The instrument cavity 5 has a proximal end 5a and a distal end 5b. The magnet 4 arranged near the release port 6 is accommodated in the instrument cavity 5 by interference fit. A pull rope 71 is provided on the tip cap 2, and a release bead is connected in series to the middle of the pull rope 71. Two groups of rope holes are relatively provided on the side walls of the instrument cavity 5, and the two groups of rope holes are respectively arranged near the proximal end 5a and the distal end 5b. The release bead is placed at the bottom of the magnet 4 and then placed in the instrument cavity 5. One end of the pull rope 71 is interference fit with the outer wall of the magnet 4 and then passes through the rope hole near the distal end 5b, then passes through the rope hole of the proximal end 5a toward the proximal end, and then extends from the opening of the proximal end 5a and is then placed outside. The other end of the pull rope 72 is interference fit with the other outer wall of the magnet 4 and then passes through the other rope hole near the distal end 5b, then passes through the other rope hole of the proximal end 5a toward the proximal end, and then extends from the opening of the proximal end 5a and is then placed outside.

[0060] Before release, the magnet 4 is located in the instrument cavity 5. When the pull rope 71 is pulled downward, the upper end of the pull rope 71 will be straightened, and the release bead will move upward, carrying the magnet 4 outward and releasing it, so that the magnet 4 enters the annular tissue 3.

[0061] The difference between this embodiment and the first embodiment is that the push rod of the first embodiment is replaced by a pull rope 71 and a release bead, and the installation positions of the installation sleeve 21 and the release sleeve 22 are different. Other structures are the same.

[0062] The above description is merely a preferred embodiment of the present invention. The scope of protection of the present invention is not limited to the above embodiment. All technical solutions based on the concept of the present invention are within the scope of protection of the present invention. It should be noted that for those skilled in the art, various improvements and modifications that do not depart from the principles of the present invention should also be considered within the scope of protection of the present invention.

Claims

1. An implantable device for enhancing the closure function of annular tissue under endoscopy, characterized by: The invention comprises a tip cap (2) mounted on the tip of an endoscope (1), the tip cap (2) being provided with an instrument cavity (5) for cooperating with and accommodating an instrument to be implanted into an annular tissue (3), the instrument cavity (5) having a proximal end (5a) and a distal end (5b), the proximal end of the instrument cavity (5) being provided with an operation port, the distal end (5b) of the instrument cavity (5) being provided with a release port (6), a locking portion being provided in the instrument cavity (5) and being movable relative to the instrument cavity (5) by an external device and having a locking position and an unlocking position, the instrument being interference-fitted in the instrument cavity (5), and the tip cap (2) being transparent; The tip cap (2) comprises a mounting sleeve (21) and a release sleeve (22) connected to each other; It also includes a release assembly (7), wherein the release assembly (7) is provided with a push portion, and the push portion is cooperatively arranged in the instrument cavity (5); The release sleeve (22) is located on the outer side wall of the mounting sleeve (21); the release assembly (7) is a pull rope assembly, and the pull rope assembly includes a pull rope (71); the pull rope (71) has a free end (71a) and a pushing portion; the pull rope (71) is movably arranged on the release sleeve (22); and the pushing portion is located in the instrument cavity (5); The pull rope assembly further includes a pushing member (72), and the pushing member (72) is cooperatively arranged on the pushing portion; At least one set of rope holes is relatively provided on the side wall of the instrument cavity (5), the middle portion of the pull rope (71) is arranged in the instrument cavity (5), and both ends of the pull rope (71) respectively pass through the rope holes and extend to the outside.

2. The endoscopic annular tissue closure enhancement implant device according to claim 1, characterized in that: The tip cap (2) is a non-magnetic tip cap.

3. The implant device for enhancing the closure function of annular tissue under endoscopy according to claim 1 or 2, characterized in that: The mounting sleeve (21) is sleeved on the front end of the endoscope (1), and the instrument cavity (5) is arranged on the release sleeve (22).

4. The implant device for enhancing the closure function of annular tissue under endoscopy according to claim 1 or 2, characterized in that: It also includes a magnet (4), which includes an implantable shell (41) and a magnetic member (42). The implantable shell (41) is arranged in the annular tissue (3), and the magnetic member (42) is movably arranged in the implantable shell (41).

5. The implant device for enhancing the closure function of annular tissue under endoscopy according to claim 4, characterized in that: The magnetic member (42) is a magnetic bead, the implantable shell (41) has a spherical cavity, and the inner diameter of the implantable shell (41) is greater than the outer diameter of the magnetic bead.

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