A health food that helps maintain healthy blood sugar and blood lipid levels and a preparation method thereof

Abstract

The present invention relates to the field of food technology, and in particular to a health food that helps maintain healthy blood sugar levels and blood lipid levels and a preparation method thereof. The following components are included in weight: 30-90 parts of sheep skim milk powder, 0.1-7 parts of coffee extract, 0.5-19 parts of mulberry leaf extract, 0.1-7 parts of plant sterol esters, 0.1-15 parts of Gynostemma pentaphyllum extract, 2-30 parts of resistant dextrin, 0.01-1.8 parts of compound vitamins, 0.01-1.2 parts of vitamin C, 0.001-0.005 parts of chromium compounds, and 0.5-10 parts of theaflavins. The preparation method includes first mixing sheep skim milk powder and resistant dextrin with water, and then shearing the plant sterol esters and the dissolved chromium compounds to obtain an emulsion 1; then dissolving the compound vitamins and shearing and mixing them with the emulsion 1, adding water to the fixed volume, homogenizing, and drying to obtain dry powder; mixing the dry powder with coffee extract, mulberry leaf extract, Gynostemma pentaphyllum extract, theaflavins compounds and vitamin C. Continuous consumption of the health food prepared by the present invention helps maintain healthy blood sugar levels and healthy blood lipid levels, improves impaired glucose tolerance, and does not cause side effects such as liver and kidney damage.

Description

Technical Field

[0001] The present invention relates to the technical field of food, and in particular to a health food that helps maintain healthy blood sugar and blood lipid levels and a preparation method thereof. Background Art

[0002] Normal sugar metabolism is a necessary way to provide energy and carbon sources for the body. Diabetes is a chronic disease caused by blood sugar metabolism in the body. Diabetes is divided into type I diabetes and type II diabetes. Type I diabetes is insulin-dependent diabetes. Most of them are caused by viruses that damage the autoimmune response mechanism covering cellular immunity and humoral immunity, resulting in reduced insulin secretion by pancreatic beta cells. Type II diabetes is also known as non-insulin-dependent diabetes. It is mostly affected by genetic or environmental factors. The therapeutic drugs are mainly divided into insulin secretion promoters, insulin sensitizers, meal blood sugar regulators, etc. The human blood sugar fluctuates with changes in diet, exercise, mood and other states. Irregular fluctuations exceed the human blood sugar regulation limit. Long-term continuation will lead to excessive use of insulin cells, causing pancreatic cell damage and impaired glucose tolerance. People with impaired glucose tolerance refer to those who exceed this blood sugar fluctuation range but do not meet the criteria for diabetes. Their hyperglycemia has shown some clinical symptoms, but has not reached the level of requiring drug treatment. This part of the population can regulate abnormal blood sugar status through diet, exercise and other means.

[0003] Blood lipids refer to lipid substances such as triglycerides, cholesterol, phospholipids, glycolipids, sterols, and steroids in plasma. Among them, triglycerides and cholesterol account for the majority. Triglycerides and cholesterol are normal substances for human life activities, but exceeding a certain amount will cause harm such as blood viscosity, blood lipid deposition, and blood vessel blockage. Different disease states will be manifested according to the different organs of deposition and blockage. If it occurs in the brain, cerebral infarction will occur, if it occurs in the cardiovascular system, coronary heart disease will occur, and if it occurs in the eyes, vision loss will occur, etc.

[0004] Glycated hemoglobin is an indicator for the diagnosis of type II diabetes. As the degree of diabetes increases, the level of glycated hemoglobin increases. Studies have found that abnormal lipid metabolism can aggravate the damage of pancreatic β-cell function and insulin resistance, and is an important factor leading to the transformation of people with impaired glucose tolerance to type II diabetes. Other studies have shown that there is an independent correlation between the increase of glycated hemoglobin and the incidence of coronary heart disease. That is, there is a correlation between high blood sugar and high blood lipids.

[0005] At present, the control of type 2 diabetes is mainly based on drugs, including metformin and α-glucosidase inhibitors that reduce sugar absorption, sulfonylurea drugs and incretins that promote insulin secretion, insulin sensitizers that increase the body's sensitivity to insulin, and direct injection of insulin. All of the above drugs have obvious side effects. In the initial use, it is necessary to reduce the dosage and gradually adapt to the normal dose before using it. However, as the disease progresses, the dosage will gradually increase, that is, it is dependent. Long-term use will cause side effects including hyperlactatemia, liver damage, hypoglycemia, and overdraft of pancreatic beta cell function. At present, the control of hyperlipidemia is also mainly based on drugs, including statins, which have a good lipid-lowering effect while increasing the incidence of liver and kidney damage and rhabdomyolysis. Statins work by inhibiting HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase, thereby preventing HMG-CoA from being converted into mevalonate to inhibit cholesterol levels, but long-term use of statins will lead to imbalance in blood sugar control.

[0006] In addition, fibrates, niacins, resins and other lipid-lowering drugs all have side effects to varying degrees.

[0007] High blood sugar and high blood lipids are often related to an unreasonable diet structure, so this group of people needs higher-quality protein sources.

[0008] For people with impaired glucose tolerance but not diagnosed with diabetes, the use of drugs will cause the risk of overtreatment for patients. However, if patients only rely on their own diet and fail to lower blood sugar, allowing blood sugar to rise beyond the insulin regulation range will lead to aggravated impaired glucose tolerance, which will persist for a long time and easily develop into diabetes. High blood sugar is related to high blood lipids, so formula foods that lower blood sugar and blood lipids at the same time are a good choice for people with impaired glucose tolerance.

[0009] Chinese invention patent application CN1244337A discloses a natural medicine health food for preventing and treating diabetes and its associated cardiovascular diseases. The invention is prepared by conventional methods using mulberry leaf extract, gynostemma pentaphyllum extract, ginkgo leaf extract, and edible organic chromium. The invention can regulate blood sugar in both directions, but the improvement of blood sugar needs to be further improved, and it only inhibits blood sugar absorption without considering the side effects caused by a large amount of carbon water entering the large intestine directly without being absorbed by the small intestine.

[0010] Chinese invention patent application CN101053592A discloses a pharmaceutical composition for treating impaired glucose tolerance and its preparation method, which is mainly composed of dried bitter melon, mulberry leaves, Panax notoginseng, Ligustrum lucidum, Gynostemma pentaphyllum, chromium picolinate, zinc gluconate, and a pharmaceutical preparation made of a pharmaceutically acceptable carrier or excipient, including capsules, granules, tablets, soft capsules, and pills. It has the effects of invigorating qi and nourishing yin, clearing away heat and activating blood circulation, and is suitable for patients with impaired glucose tolerance and early and mild diabetes. However, the drug cannot regulate blood lipids, and its improvement effect on impaired glucose tolerance needs to be improved. Summary of the invention

[0011] In view of the shortcomings of the prior art, the present invention provides a health food that helps maintain healthy blood sugar levels and healthy blood lipid levels and a preparation method thereof. The health food helps maintain healthy blood sugar levels and healthy blood lipid levels, improves impaired glucose tolerance, and does not cause side effects such as liver and kidney damage.

[0012] The objective of the present invention is achieved through the following technical solutions:

[0013] A health food that helps maintain healthy blood sugar and blood lipid levels, comprising the following components in parts by weight: 30-90 parts of sheep skim milk powder, 0.1-7 parts of coffee extract, 0.5-19 parts of mulberry leaf extract, 0.1-7 parts of phytosterol esters, 0.1-15 parts of Gynostemma pentaphyllum extract, 2-30 parts of resistant dextrin, 0.01-1.8 parts of complex vitamins, 0.01-1.2 parts of vitamin C, 0.001-0.005 parts of chromium compounds, and 0.5-10 parts of theaflavins compounds.

[0014] Preferably, the above health food comprises the following components in parts by weight: 30-80 parts of sheep skim milk powder, 2-5 parts of coffee extract, 1.1-2.0 parts of mulberry leaf extract, 1-2.5 parts of phytosterol esters, 0.5-2.2 parts of Gynostemma pentaphyllum extract, 15-30 parts of resistant dextrin, 0.01-0.7 parts of complex vitamins, 0.01-1.0 parts of vitamin C, 0.001-0.005 parts of chromium compounds, and 0.5-2.9 parts of theaflavins compounds.

[0015] Preferably, the above health food comprises the following components in parts by weight: 30-80 parts of sheep skim milk powder, 2-5 parts of coffee extract, 1.1-1.7 parts of mulberry leaf extract, 1-2 parts of phytosterol esters, 0.5-0.8 parts of Gynostemma pentaphyllum extract, 15-30 parts of resistant dextrin, 0.01-0.5 parts of complex vitamins, 0.01-1.0 parts of vitamin C, 0.001-0.005 parts of chromium compounds, and 0.5-2.9 parts of theaflavins compounds.

[0016] Preferably, the above health food comprises the following components in parts by weight: 50-70 parts of sheep skim milk powder, 2-5 parts of coffee extract, 1.1-1.7 parts of mulberry leaf extract, 1-2 parts of phytosterol esters, 0.5-0.8 parts of Gynostemma pentaphyllum extract, 15-25 parts of resistant dextrin, 0.01-0.2 parts of complex vitamins, 0.01-1.0 parts of vitamin C, 0.001-0.003 parts of chromium compounds, and 0.5-2.5 parts of theaflavins compounds.

[0017] Preferably, the goat skim milk powder is skim milk powder from goats or sheep, and its protein content ranges from 60% to 98%.

[0018] Preferably, the goat skim milk powder does not contain lactose.

[0019] Preferably, the coffee extract is extracted from Arabica coffee beans, and the coffee extract contains 20%-80% chlorogenic acid, 5%-50% 5-caffeoylquinic acid, and 0.2%-10% caffeine.

[0020] Preferably, the plant sterol ester is prepared by esterifying, deacidifying, distilling, adding vitamin E and ascorbyl palmitate, filling and cooling the plant sterol.

[0021] Preferably, the phytosterols used are prepared enzymatically.

[0022] Preferably, the phytosterol ester used comprises at least one of a powder or an oil, wherein the content of the phytosterol ester in the powder is 30%-70%, and the content of the phytosterol ester in the oil is 50%-99%.

[0023] Preferably, the resistant dextrin is Fibersol-2 resistant dextrin.

[0024] Preferably, the chromium compound is one or more of nicotinate chromium, amino acid chromium, pyridine carboxylic acid chromium, chromium-added composite fiber, chromium gluconate and chromium-enriched yeast;

[0025] Preferably, the theaflavin compound is one or more of theaflavin, theaflavin-3-gallate, theaflavin-3′-gallate and theaflavin-3,3′-digallate.

[0026] Another object of the present invention is to provide a method for preparing the above-mentioned health food that helps maintain healthy blood sugar levels and healthy blood lipid levels, comprising the following steps:

[0027] (1) mixing sheep skim milk powder and resistant dextrin with water to prepare a mixed solution;

[0028] (2) dissolving the chromium compound in water, then adding the phytosterol ester and the dissolved chromium compound into the mixed solution, and shearing to obtain an emulsion 1;

[0029] (3) Dissolving the compound vitamins in water alone and mixing the mixture with emulsion 1 to obtain emulsion 2;

[0030] (4) Add water to the emulsion 2 to make up the volume, homogenize, sterilize, concentrate, and dry to obtain a dry powder;

[0031] (5) The dry powder is mixed with coffee extract, mulberry leaf extract, Gynostemma pentaphyllum extract, theaflavins compounds and vitamin C to obtain the product.

[0032] Preferably, the mass ratio of the sheep skim milk powder and resistant dextrin to water is 1:0.8-1.2; and the temperature of the water is 60-70°C.

[0033] Preferably, after the emulsion 1 is obtained by shearing in step (4), 60-70°C water is added to make the volume until the mass ratio of solute to water in the emulsion is 1:5-8; the homogenization flow rate in step (4) is 10 tons / hour, and the sterilization is sterilized at 105-120°C for 2-10s.

[0034] Another object of the present invention is to provide the use of the above-mentioned health food in the preparation of products that help maintain healthy blood sugar levels and healthy blood lipid levels.

[0035] Beneficial effects of the present invention:

[0036] (1) The present invention is aimed at people with impaired glucose tolerance. Currently, there is no technology or invention health food for this group of people. Inventions or medicines of hypoglycemic and lipid-lowering drugs are not suitable for this group of people because of their large side effects. The present invention is taken with meals on a daily basis and will not cause side effects that hypoglycemic drugs are prone to, such as hyperlactatemia, liver damage, hypoglycemia, and overdraft of pancreatic β-cell function. It also will not cause side effects that lipid-lowering drugs are prone to, such as liver damage, kidney damage, and rhabdomyolysis.

[0037] (2) The existing technology has poor effects on lowering blood sugar or blood lipids alone, and is prone to relapse. The present invention fully studies the correlation between hyperglycemia and hyperlipidemia, and reduces the incidence of hyperlipidemia while blocking the hyperglycemia pathway. The composition of the present invention helps to maintain healthy blood sugar and blood lipid levels. The coffee extract and Gynostemma pentaphyllum extract have both blood sugar and blood lipid lowering effects. Mulberry leaf extract, resistant dextrin, compound vitamins, vitamin C, and chromium compounds can lower blood sugar overall by blocking carbohydrate absorption, accelerating blood sugar utilization, and increasing cell insulin receptor activity. They synergistically reduce the digestion and absorption of cholesterol and triglycerides with plant sterol esters and theaflavins compounds, further promoting the blood sugar lowering effect.

[0038] (3) The present invention adds goat skim milk powder as a source of high-quality protein. It improves the body's intake of high-quality protein, accelerates muscle synthesis and increases exercise capacity, and fundamentally blocks the occurrence of high blood lipids and high blood sugar. Conventional milk powder often contains a large amount of lactose, while goat skim milk powder does not contain lactose and is more suitable for people with lactose intolerance.

[0039] (4) While reducing blood sugar absorption, the prior art will cause a large amount of undigested carbohydrates to enter the large intestine, causing gastrointestinal discomfort. The resistant dextrin added in the present invention can also be used as a prebiotic to proliferate beneficial bacteria, increase intestinal motility, and reduce the incidence of gastrointestinal discomfort. DETAILED DESCRIPTION

[0040] The present invention will be further described below in conjunction with specific embodiments.

[0041] All raw materials in the following examples are commercially available conventional raw materials. Sheep skim milk powder was purchased from Qingdao Ruobilin Trading Co., Ltd. and treated with a lactose removal process, coffee extract was purchased from Nanjing Jienuo Biological Products Co., Ltd., mulberry leaf extract was purchased from DSM (China) Co., Ltd., Gynostemma pentaphyllum extract was purchased from Guangzhou Dongyi Nutrition Technology Co., Ltd., phytosterol ester powder content was 67%, phytosterol ester oil content was 97%, both were purchased from Guangzhou Xinhe Health Technology Co., Ltd.; Fibersol-2 resistant dextrin was purchased from Guangzhou Huagong Biotechnology Co., Ltd., compound vitamins were purchased from Beijing Jinkangpu Food Technology Co., Ltd., and chromium compounds such as chromium-rich yeast were purchased from Angel Yeast Co., Ltd.

[0042] Example 1

[0043] A health food that helps maintain healthy blood sugar and blood lipid levels. The raw materials include the following components by weight: 63.8 parts of sheep skim milk powder, 2.0 parts of coffee extract, 1.7 parts of mulberry leaf extract, 0.8 parts of Gynostemma pentaphyllum extract, 2.0 parts of phytosterol ester powder, 24.6 parts of Fibersol-2 resistant dextrin, 0.7 parts of complex vitamins, 1.0 parts of vitamin C, 0.002 parts of chromium-enriched yeast, and 2.9 parts of theaflavins.

[0044] The preparation of this embodiment adopts a dry-wet composite process, which specifically includes the following steps:

[0045] (1) Accurately weigh: sheep skim milk powder, Fibersol-2 resistant dextrin, compound vitamins, chromium compounds and other raw materials.

[0046] (2) Using a powder-water mixer, sheep skim milk powder, resistant dextrin and water are mixed in a ratio of 1:1 to obtain a sheep skim milk powder mixed solution, wherein the water used is purified water at 65°C. Chromium compounds and complex vitamins are separately dissolved in water.

[0047] (3) Shearing: Add the weighed phytosterol ester and dissolved chromium-enriched yeast into the mixed sheep skim milk powder mixture, and shear to obtain emulsion 1. Add the separately dissolved (dissolving temperature 40°C) complex vitamins into emulsion 1, and shear for 15 minutes to obtain emulsion 2.

[0048] (4) Use 65℃ pure water to make the emulsion 2 after shearing to a powder-water mixing ratio of 1:5, that is, make the volume to 6 tons per ton of powder. Use a homogenizer to homogenize the emulsion, and the homogenization flow rate needs to be controlled at 10 tons / hour. Use high temperature sterilization, 110℃, 6S for sterilization. Concentrate by using the method of reduced pressure concentration at low temperature 46℃-75℃, by reducing the gas pressure to make the liquid boil and concentrate. Concentrate to a concentration of 45-48%.

[0049] (5) Spray drying to obtain dry powder.

[0050] The specific process steps are as follows: turn on the air inlet fan, exhaust fan, high-pressure pump, frequency converter, and cooling fan in sequence, and adjust the exhaust fan frequency to display the negative pressure in the tower at about 0 to -20 Pa. Turn on the Roots blower, and then open the first and second level star valves to adjust the negative pressure in the tower to about -10 to -30Pa. Turn on the first, second, and third stage fans of the fluidized bed, the vibrating screen, and the three-stage fluidized bed vibration motor in sequence, adjust the air inlet and exhaust fan frequencies to keep the negative pressure in the tower between 0 and -30 Pa, and gradually increase the air inlet and exhaust fan frequencies. When the exhaust fan frequency reaches about 20Hz, adjust the air inlet frequency to control the negative pressure in the tower to about -20 to -35Pa. Open the air hammer, open the air inlet valve of the heater at the same time, open the electronic valve of the first spray gun, and open the oil pump and circulating cooling water of the high-pressure pump at the same time. When the exhaust temperature reaches about 105℃, start the high-pressure pump and feed pump, adjust the frequency and pressure of the high-pressure pump to above 200bar, then open the electronic valve of the second gun, adjust the frequency of the high-pressure pump, and make the pressure of the high-pressure pump above 180bar. Open the steam valve of the tower top heater, and when the exhaust temperature continues to rise at 70℃, open the electronic valves of the third, fourth and fourth spray guns, adjust the pressure of the high-pressure pump to about 250bar, adjust the pressure of the high-pressure pump to control the exhaust temperature, and maintain the negative pressure between -10Pa and -50Pa during the whole operation.

[0051] (6) Mix the dry powder, coffee extract, mulberry leaf extract, Gynostemma pentaphyllum extract, theaflavins and vitamin C. Use 10% of the spray-dried dry powder for primary mixing, the mixing time is 15 minutes, and the mixing frequency is 40 Hz. Use 80% of the spray-dried dry powder and the primary mixed powder for secondary mixing, the mixing time is 15 minutes, and the mixing frequency is 40 Hz. Use the secondary mixed powder to mix with the remaining spray-dried dry powder, the mixing time is 20 minutes, and the mixing frequency is 40 Hz.

[0052] Example 2

[0053] A health food that helps maintain healthy blood sugar and blood lipid levels. The raw materials include the following components by weight: 60.76 parts of sheep skim milk powder, 2.0 parts of coffee extract, 1.5 parts of mulberry leaf extract, 0.5 parts of Gynostemma pentaphyllum extract, 2.5 parts of phytosterol ester oil, 28.0 parts of Fibersol-2 resistant dextrin, 0.24 parts of complex vitamins, 0.11 parts of vitamin C, 0.004 parts of chromium compounds, and 3.0 parts of theaflavins.

[0054] The product of this embodiment is manufactured by a dry-wet composite process, which is basically the same as that of embodiment 1, except for the fine adjustment of parameters. The details are as follows:

[0055] (1) Accurately weigh: sheep skim milk powder, Fibersol-2 resistant dextrin, compound vitamins, chromium compounds and other raw materials.

[0056] (2) Using a powder-water mixer, mix sheep skim milk powder, resistant dextrin and water in a ratio of 1:1.2 to obtain a mixed solution, wherein the water used is 70°C purified water. Chromium compounds and complex vitamins are separately dissolved in water.

[0057] (3) Shearing: add the weighed phytosterol ester oil and dissolved mineral chromium into the mixed sheep skim milk powder mixture, shear, and obtain emulsion 1. Add the separately dissolved (dissolving temperature 50°C) complex vitamins into emulsion 1, shear for 15 minutes, and obtain emulsion 2.

[0058] (4) Use 65℃ pure water to make the emulsion 2 after shearing to a powder-water mixing ratio of 1:8, that is, make the volume to 8 tons per ton of powder. Pass the emulsion through a homogenizer for homogenization, and the homogenization flow rate needs to be controlled at 10 tons / hour. Sterilize by high temperature, 120℃, 3S. Concentrate by using the method of reduced pressure concentration, at a low temperature of 46℃, by reducing the gas pressure to make the liquid boil and concentrate. Concentrate to a concentration of 45-48%.

[0059] (5) Spray drying to obtain dry powder.

[0060] The specific process steps are as follows: turn on the air inlet fan, exhaust fan, high-pressure pump, frequency converter, and cooling fan in sequence, and adjust the exhaust fan frequency to display the negative pressure in the tower at about 0 to -20 Pa. Turn on the Roots blower, and then open the first and second level star valves to adjust the negative pressure in the tower to about -10 to -30Pa. Turn on the first, second, and third stage fans of the fluidized bed, the vibrating screen, and the three-stage fluidized bed vibration motor in sequence, adjust the air inlet and exhaust fan frequencies to keep the negative pressure in the tower between 0 and -30 Pa, and gradually increase the air inlet and exhaust fan frequencies. When the exhaust fan frequency reaches about 20Hz, adjust the air inlet frequency to control the negative pressure in the tower to about -20 to -35Pa. Open the air hammer, open the air inlet valve of the heater at the same time, open the electronic valve of the first spray gun, and open the oil pump and circulating cooling water of the high-pressure pump at the same time. When the exhaust temperature reaches about 105℃, start the high-pressure pump and feed pump, adjust the frequency and pressure of the high-pressure pump to above 200bar, then open the electronic valve of the second gun, adjust the frequency of the high-pressure pump, and make the pressure of the high-pressure pump above 180bar. Open the steam valve of the tower top heater, and when the exhaust temperature continues to rise at 70℃, open the electronic valves of the third, fourth and fourth spray guns, adjust the pressure of the high-pressure pump to about 250bar, adjust the pressure of the high-pressure pump to control the exhaust temperature, and maintain the negative pressure between -10Pa and -50Pa during the whole operation.

[0061] (6) Mix the dry powder, coffee extract, mulberry leaf extract, Gynostemma pentaphyllum extract, theaflavins and vitamin C. Use 20% of the spray-dried dry powder for primary mixing, the mixing time is 15 minutes, and the mixing frequency is 40 Hz. Use 70% of the spray-dried powder and the primary mixed powder for secondary mixing, the mixing time is 15 minutes, and the mixing frequency is 40 Hz. Use the secondary mixed powder to mix with the remaining spray-dried powder, the mixing time is 20 minutes, and the mixing frequency is 40 Hz.

[0062] Example 3

[0063] A health food that helps maintain healthy blood sugar and blood lipid levels. The raw materials include the following components by weight: 66.4 parts of sheep skim milk powder, 2.5 parts of coffee extract, 1.9 parts of mulberry leaf extract, 0.6 parts of Gynostemma pentaphyllum extract, 1.7 parts of phytosterol ester powder, 22 parts of Fibersol-2 resistant dextrin, 0.2 parts of complex vitamins, 0.2 parts of vitamin C, 0.005 parts of chromium compounds, and 4 parts of theaflavins.

[0064] The preparation of this embodiment adopts a dry-wet composite process, which specifically includes the following steps:

[0065] (1) Accurately weigh: sheep skim milk powder, Fibersol-2 resistant dextrin, compound vitamins, chromium compounds and other raw materials.

[0066] (2) Using a powder-water mixer, sheep skim milk powder, resistant dextrin and water are mixed in a ratio of 1:1 to obtain a sheep skim milk powder mixed solution, wherein the water used is 60°C purified water. Chromium compounds and complex vitamins are separately dissolved in water.

[0067] (3) Shearing: Add the weighed phytosterol ester and dissolved chromium-enriched yeast into the mixed sheep skim milk powder mixture, and shear to obtain emulsion 1. Add the separately dissolved (dissolving temperature 40°C) complex vitamins into emulsion 1, and shear for 15 minutes to obtain emulsion 2.

[0068] (4) Use 65℃ pure water to make the emulsion 2 after shearing to a powder-water mixing ratio of 1:5, that is, make the volume to 6 tons per ton of powder. Use a homogenizer to homogenize the emulsion, and the homogenization flow rate needs to be controlled at 10 tons / hour. Use high temperature sterilization, 110℃, 6S for sterilization. Concentrate by using the method of reduced pressure concentration at low temperature 46℃-75℃, by reducing the gas pressure to make the liquid boil and concentrate. Concentrate to a concentration of 45-48%.

[0069] (5) Spray drying to obtain dry powder. The specific process is the same as that in Example 1.

[0070] (6) Mix the dry powder, coffee extract, mulberry leaf extract, Gynostemma pentaphyllum extract, theaflavins and vitamin C. Use 10% of the spray-dried dry powder for primary mixing, the mixing time is 15 minutes, and the mixing frequency is 40 Hz. Use 80% of the spray-dried dry powder and the primary mixed powder for secondary mixing, the mixing time is 15 minutes, and the mixing frequency is 40 Hz. Use the secondary mixed powder to mix with the remaining spray-dried dry powder, the mixing time is 20 minutes, and the mixing frequency is 40 Hz.

[0071] Example 4

[0072] A health food that helps maintain healthy blood sugar and blood lipid levels. The raw materials include the following components by weight: 53.2 parts of sheep skim milk powder, 3.1 parts of coffee extract, 0.5 parts of mulberry leaf extract, 2.2 parts of Gynostemma pentaphyllum extract, 5.2 parts of phytosterol ester powder, 30 parts of Fibersol-2 resistant dextrin, 0.02 parts of complex vitamins, 1.2 parts of vitamin C, 0.004 parts of chromium compounds, and 3 parts of theaflavin-3-gallate.

[0073] The product of this embodiment is manufactured by a dry-wet composite process, which is the same as the preparation method of embodiment 1.

[0074] Example 5

[0075] A health food that helps maintain healthy blood sugar and blood lipid levels. The raw materials include the following components by weight percentage: 50 parts of sheep skim milk powder, 5 parts of coffee extract, 17 parts of mulberry leaf extract, 0.8 parts of Gynostemma pentaphyllum extract, 2 parts of phytosterol ester oil, 15 parts of Fibersol-2 resistant dextrin, 1.5 parts of complex vitamins, 0.03 parts of vitamin C, 0.001 parts of chromium compounds, and 8 parts of theaflavin-3′-gallate and theaflavin-3,3′-digallate.

[0076] The product of this embodiment is manufactured by a dry-wet composite process, which is the same as the preparation method of embodiment 1.

[0077] Comparative Example 1

[0078] This comparative example differs from Example 1 in that it does not contain phytosterol esters and theaflavins, and the remaining raw materials are composed as follows:

[0079] 63.8 parts of sheep skim milk powder, 2.0 parts of coffee extract, 6.597 parts of mulberry leaf extract, 0.8 parts of Gynostemma pentaphyllum extract, 24.6 parts of Fibersol-2 resistant dextrin, 0.7 parts of complex vitamins, 1.0 parts of vitamin C, and 0.005 parts of chromium-enriched yeast.

[0080] The product of this comparative example is produced by a dry-wet composite process, which is the same as that of Example 1.

[0081] Comparative Example 2

[0082] This comparative example differs from Example 1 in that it does not contain mulberry leaf extract and chromium compound, and the remaining raw materials are composed as follows:

[0083] 63.8 parts of sheep skim milk powder, 2.0 parts of coffee extract, 0.8 parts of Gynostemma pentaphyllum extract, 3.0 parts of phytosterol ester powder, 24.6 parts of Fibersol-2 resistant dextrin, 0.7 parts of complex vitamins, 1.0 parts of vitamin C, and 3.602 parts of theaflavins.

[0084] The product of this comparative example is produced by a dry-wet composite process, which is the same as that of Example 1.

[0085] Comparative Example 3

[0086] The difference between this comparative example and Example 1 is that theaflavins and mulberry leaf extract are removed, and the remaining raw materials are composed as follows:

[0087] 63.8 parts of sheep skim milk powder, 2.0 parts of coffee extract, 0.8 parts of Gynostemma pentaphyllum extract, 6.597 parts of phytosterol ester powder, 24.6 parts of Fibersol-2 resistant dextrin, 0.7 parts of complex vitamins, 1.0 parts of vitamin C, and 0.005 parts of chromium compounds.

[0088] The product of this comparative example is produced by a dry-wet composite process, which is the same as that of Example 1.

[0089] Comparative Example 4

[0090] The difference between this comparative example and Example 1 is that the ratio of each raw material is different, and the specific composition is as follows:

[0091] A health food that helps maintain healthy blood sugar and blood lipid levels. The raw materials include the following components by weight: 63.8 parts of sheep skim milk powder, 9 parts of coffee extract, 0.3 parts of mulberry leaf extract, 17 parts of Gynostemma pentaphyllum extract, 8 parts of phytosterol ester powder, 0.5 parts of Fibersol-2 resistant dextrin, 0.4 parts of complex vitamins, 0.3 parts of vitamin C, 0.002 parts of chromium, and 0.2 parts of theaflavins.

[0092] The product of this comparative example is produced by a dry-wet composite process, which is the same as that of Example 1.

[0093] Trial 1: Blood sugar lowering trial

[0094] SPF male KM mice were selected, weighing 20±2g, free diet, and adaptive feeding for 3-5 days. After fasting for 16 hours, their blood sugar level, body weight, and water intake were tested. The content of streptozotocin, a modeling drug, was determined according to the body weight value, and the solution was prepared. 50 mg / kg body weight was injected intraperitoneally for 5 consecutive days, once a day. After the last injection, fasting for 16 hours, blood sugar levels were measured, and the model was successful if blood sugar was higher than 11.1mmoL / L.

[0095] The model mice were divided into a positive control group, a model group, Example 1, Example 2, Example 3, Comparative Example 1, Comparative Example 2, Comparative Example 3, and Comparative Example 4. After successful modeling, the positive control group was subcutaneously injected with insulin 0.5U / mL, 0.054mL / 10g body weight, the model group was gavaged with the same volume of normal saline, and the other groups were gavaged with the corresponding test samples for 14 consecutive days, with a gavage dose of 800mg / kg / d. Blood was collected on the 14th day to test blood sugar and various indicators.

[0096] The test results are shown in Table 1 below:

[0097] Table 1 Blood glucose test results (14 days)

[0098]

[0099] Note: Different letters in the same column indicate significant statistical differences between the corresponding groups, P < 0.05.

[0100] As can be seen from Table 1, each test group showed significant differences from the model group (p<0.05), and the model group showed obvious hyperglycemia (hyperglycemia, polydipsia, polyphagia), indicating that the model structure is reasonable. The positive group used subcutaneous injection of insulin, which had a significant effect on controlling blood sugar. During the experiment, the injection was continued every day, and the blood sugar of the mice was stable. Example 1, Example 2, and Example 3 used complete formulas, and there were no significant differences between the groups. Comparative Example 1, Comparative Example 2, and Comparative Example 3 used abbreviated formulas, and Comparative Example 4 used an unreasonable ratio. As can be seen from the data in Table 1, the embodiments can better control blood sugar, and each indicator is significantly better than the model group. The effect of improving blood sugar in Comparative Examples 1-4 is worse than that of each embodiment group.

[0101] From the above results, it can be seen that the embodiment can significantly reduce blood sugar levels, and long-term use helps maintain healthy blood sugar levels. The formula comparison study found that the comparative example deleted the blood sugar-lowering component or the blood lipid-lowering component, and the performance was worse than that of the embodiment, indicating that the blood sugar-lowering component and the blood lipid-lowering component have a synergistic effect. Lowering blood sugar or blood lipids alone has limited or slow improvements on high blood sugar. This unobvious improvement is not conducive to long-term use by the user population.

[0102] Test 2: Blood lipid test

[0103] Kunming mice were selected, with 10 mice per group (20±2g), and were adaptively raised for 1 week with free access to food and water. They were fed a high-fat diet for 10 days, and then blood was collected from the orbital venous plexus, and serum was separated by centrifugation to determine serum TG, TC, HDL-C, and LDL-C levels. Ten days after modeling, the TC value (5.674±0.641mmol / L) of the experimental mice was higher than that of normal mice (2.417±0.326mmol / L) (p<0.001), and the TG value (1.832±0.218mmol / L) was higher than that of normal mice (1.102±0.129mmol / L) (p<0.001), indicating that the modeling was successful.

[0104] The mice with successful modeling were divided into a positive control group, a model group, Example 1, Example 2, Example 3, Comparative Example 1, Comparative Example 2, Comparative Example 3, and Comparative Example 4. The positive control group was gavaged with simvastatin at 10 mg / kg / day, the model group was gavaged with the same volume of normal saline, and the other groups were gavaged with the corresponding test samples for 14 consecutive days. Blood was collected on the 14th day to detect various blood lipid indicators.

[0105] The test results are shown in Table 2 below:

[0106] Table 2. Blood lipid test results (14 days)

[0107]

[0108] Note: Different letters in the same column indicate significant statistical differences between the corresponding groups, P < 0.05.

[0109] As shown in Table 2, each test group showed significant differences from the model group (p<0.05), and the model group showed obvious hyperlipidemia, indicating that the model structure was reasonable. The positive control group was given simvastatin every day, and the blood lipid control effect was obvious. Example 1, Example 2, and Example 3 used complete formulas, and there was no significant difference between the groups. Comparative Examples 1, 2, and 3 used deleted formulas, and Comparative Example 4 used unreasonable formula ratios, and their lipid-lowering effects were not as good as the example formulas. Among them, Comparative Example 1, which deleted plant sterol esters and theaflavins, had a lipid-lowering effect lower than Comparative Example 2, which retained plant sterol esters and theaflavins.

[0110] It can be seen from the above results that the embodiment group helps to maintain the effect of healthy blood lipid levels during the test. At the same time, the formula comparison study found that when the formula contains both the glucose-lowering component and the lipid-lowering component of the present invention, the lipid-lowering effect is more obvious, and the specific glucose-lowering components and the lipid-lowering components have a synergistic effect on the reduction of blood lipids. By comparing Comparative Example 2 with the embodiment, it can be found that, while keeping the total number of parts unchanged, the lipid-lowering effect of Example 1 and Example 2 after adding the specific glucose-lowering component mulberry leaf extract and chromium compound is more obvious than that of Comparative Example 2 alone.

[0111] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A health food that helps maintain healthy blood sugar levels and healthy blood lipid levels, characterized in that: The components are as follows: The raw materials include the following components by weight percentage: 63.8 parts of sheep skim milk powder, 2.0 parts of coffee extract, 1.7 parts of mulberry leaf extract, 0.8 parts of Gynostemma pentaphyllum extract, 2.0 parts of phytosterol esters, 24.6 parts of Fibersol-2 resistant dextrin, 0.7 parts of complex vitamins, 1.0 parts of vitamin C, 0.002 parts of chromium-enriched yeast, and 2.9 parts of theaflavins; The goat skim milk powder is skim milk powder from goats or sheep, and its protein content ranges from 60% to 98%, and the goat skim milk powder does not contain lactose; The coffee extract is extracted from Arabica coffee beans, and the coffee extract contains 20%-80% chlorogenic acid, 5%-50% 5-caffeoylquinic acid, and 0.2%-10% caffeine; The phytosterol ester is prepared by an enzymatic method, and the phytosterol ester used includes at least one of a powder or an oil, wherein the content of the phytosterol ester in the powder is 30%-70%, and the content of the phytosterol ester in the oil is 50%-99%.

2. A health food that helps maintain healthy blood sugar and blood lipid levels, characterized in that: The raw materials include the following components by weight percentage: 60.76 parts of sheep skim milk powder, 2.0 parts of coffee extract, 1.5 parts of mulberry leaf extract, 0.5 parts of Gynostemma pentaphyllum extract, 2.5 parts of phytosterol ester oil, 28.0 parts of Fibersol-2 resistant dextrin, 0.24 parts of complex vitamins, 0.11 parts of vitamin C, 0.004 parts of chromium compounds, and 3.0 parts of theaflavins; The goat skim milk powder is skim milk powder from goats or sheep, and its protein content ranges from 60% to 98%, and the goat skim milk powder does not contain lactose; The coffee extract is extracted from Arabica coffee beans, and the coffee extract contains 20%-80% chlorogenic acid, 5%-50% 5-caffeoylquinic acid, and 0.2%-10% caffeine; The phytosterol ester is prepared by an enzymatic method, and the phytosterol ester used includes at least one of a powder or an oil, wherein the content of the phytosterol ester in the powder is 30%-70%, and the content of the phytosterol ester in the oil is 50%-99%.

3. A health food that helps maintain healthy blood sugar and blood lipid levels, characterized in that: The raw materials include the following components by weight percentage: 66.4 parts of sheep skim milk powder, 2.5 parts of coffee extract, 1.9 parts of mulberry leaf extract, 0.6 parts of Gynostemma pentaphyllum extract, 1.7 parts of phytosterol ester powder, 22 parts of Fibersol-2 resistant dextrin, 0.2 parts of complex vitamins, 0.2 parts of vitamin C, 0.005 parts of chromium compounds, and 4 parts of theaflavins; The goat skim milk powder is skim milk powder from goats or sheep, and its protein content ranges from 60% to 98%, and the goat skim milk powder does not contain lactose; The coffee extract is extracted from Arabica coffee beans, and the coffee extract contains 20%-80% chlorogenic acid, 5%-50% 5-caffeoylquinic acid, and 0.2%-10% caffeine; The phytosterol ester is prepared by an enzymatic method, and the phytosterol ester used includes at least one of a powder or an oil, wherein the content of the phytosterol ester in the powder is 30%-70%, and the content of the phytosterol ester in the oil is 50%-99%.

4. A method for preparing the health food that helps maintain healthy blood sugar and blood lipid levels according to any one of claims 1 to 3, characterized in that: The steps include: (1) mixing goat skim milk powder and resistant dextrin with water to prepare a mixed solution; (2) dissolving the chromium compound in water, then adding the phytosterol ester and the dissolved chromium compound into the mixed solution, and shearing to obtain an emulsion 1; (3) Dissolving the compound vitamins in water alone and then shearing and mixing with emulsion 1 to obtain emulsion 2; (4) Add water to the emulsion 2 to make up the volume, homogenize, sterilize, concentrate, and dry to obtain a dry powder; (5) The dry powder is mixed with coffee extract, mulberry leaf extract, Gynostemma pentaphyllum extract, theaflavins compounds and vitamin C to obtain the product.

5. The preparation method according to claim 4, characterized in that: In step (1), the mass ratio of the sheep skim milk powder and the resistant dextrin to the water is 1:0.8-1.2; and the temperature of the water is 60-70°C.

6. The preparation method according to claim 4, characterized in that: The volume setting in step (4) is to set the volume to a mass ratio of solute to water in the emulsion of 1:5-8; the homogenization flow rate in step (4) is 10 tons / hour, and the sterilization is sterilization at 105-120°C for 2-10s.

7. Use of the health food according to any one of claims 1 to 3 in preparing products that help maintain healthy blood sugar levels and healthy blood lipid levels.

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