Preparation method of collagen and anti-propionibacterium acnes gamma protein combined preparation

Through the preparation of a combined preparation of collagen and anti-acne Propionibacterium acnes gamma protein, the problem of reduced therapeutic effect of anti-acne Propionibacterium acnes drugs is solved, effective suppression of acne and skin repair are achieved, and the development of drug resistance is avoided.

CN114558130AActive Publication Date: 2022-05-31GUANGXI BOSHENG BIOTECHNOLOGY CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
GUANGXI BOSHENG BIOTECHNOLOGY CO LTD
Filing Date
2022-03-19
Publication Date
2022-05-31

AI Technical Summary

Technical Problem

The therapeutic effect of existing anti-P. acnes drugs is reduced due to increased drug resistance, and it is difficult to effectively inhibit the inflammatory response of acne and related diseases.

Method used

The preparation method of the combined preparation of collagen and anti-Acnes Propionibacterium acnes gamma protein is used to prepare the anti-Acnes Propionibacterium acnes gamma protein and recombinant type III collagen, and under the action of a neutralizing agent, the anti-Pionibacterium acnes gamma protein is achieved. Effective inhibition and skin repair.

Benefits of technology

Significantly improves the inhibitory effect on Propionibacterium acnes, shortens the treatment cycle, avoids the development of drug resistance, and promotes cell growth and skin repair.

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Abstract

The invention relates to the technical field of biological medicine, and particularly discloses a preparation method of a collagen and anti-propionibacterium acnes gamma protein combined preparation, and the preparation method of the collagen and anti-propionibacterium acnes gamma protein combined preparation comprises the following steps: preparing anti-propionibacterium acnes gamma protein; adding water into the anti-propionibacterium acnes gamma protein and the recombinant III-type collagen, stirring and mixing, adding glycerol and a neutralizing agent, and mixing to obtain a uniform solution; the preparation method comprises the following steps: dispersing carbomer with water, adding a preservative and a humectant, mixing, finally adding the uniform solution, and mixing to obtain the required collagen and anti-propionibacterium acnes gamma protein combined preparation. The combined preparation prepared by the method can be used for effectively treating acnes, is remarkable in curative effect, does not generate drug resistance, is short in treatment cycle, can quickly eliminate skin damage, promote cell growth and adhesion and repair skin barriers, and does not generate new rash after healing.
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Citation Information

Patent Citations

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