Application of pharmaceutical by-products of Isatis indigotica

By processing Isatis root residue into solid residue and adding it to piglet feed, the intestinal flora and liver function can be regulated, thus addressing the insufficient application of Isatis root pharmaceutical by-products in piglet farming. This results in improved intestinal flora and liver function, enhancing piglet health and farming efficiency.

CN117243983BActive Publication Date: 2025-12-02GUANGZHOU BAIYUSN HUTCHISON WHAMPOA CHINESE MEDICINE
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Patent Information

Application Number
CN202311311885.2
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-10-10
Publication Date
2025-12-02
Estimated Expiration
2043-10-10

AI Technical Summary

Technical Problem

In the existing technology, the application of Isatis root pharmaceutical by-products in regulating the intestinal flora and improving liver function in piglets has not been fully studied. Moreover, the related products are difficult to obtain and costly, which limits their promotion in breeding. At the same time, piglets often experience intestinal flora disorder and liver and kidney damage after weaning.

Method used

The residue of Isatis root is extracted by boiling in water, filtered and separated, then dried and pulverized to produce a solid residue substance with a water content of ≤12wt%. This substance is added to piglet feed to regulate intestinal flora and improve liver function. Specific components include L-arginine, guanine, L-phenylalanine, epigallocatechin, deoxydaunocarbazine, 3-indoleacetonitrile, indigo, and indirubin, which reduce the abundance of specific bacterial groups and serum indicators.

Benefits of technology

It effectively regulates the intestinal flora of piglets, reduces the abundance of specific bacteria, improves liver function and lipid metabolism, reduces weaning stress response, improves health status and breeding efficiency, reduces serum enzyme and bile acid levels, and increases serum protein content.

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Abstract

This invention discloses the application of pharmaceutical by-products from Isatis indigotica, belonging to the field of livestock breeding technology. The application of these by-products involves regulating the intestinal flora of piglets, improving liver function, or improving lipid metabolism in piglets. This invention utilizes Isatis indigotica by-products to regulate the intestinal flora, improve liver function, or improve lipid metabolism in piglets. After weaning, this effectively improves intestinal flora imbalance, liver damage, and glucose and lipid metabolism disorders caused by early weaning stress in piglets, thereby effectively reducing adverse stress responses during weaning, improving piglet health, and increasing breeding efficiency.
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