Composition for reducing neck wrinkles, neck mask and preparation method thereof

Abstract

The present invention belongs to the field of neck care, specifically relating to a composition for reducing neck wrinkles, a neck mask, and a preparation method thereof. The composition comprises ingredients such as: Polygonum multiflorum extract, Polygonum aviculare extract, hydroxypropyltrimonium chloride hyaluronic acid, dipeptide diaminobutyryl benzylamide diacetate, and acetyl glucosamine. The composition for reducing neck wrinkles prepared by the present invention, wherein the components cooperate with each other in specific proportions, effectively reduces neck wrinkles through moisturizing, repairing, and inhibiting mechanisms, resulting in a smoother and firmer neck skin. The resulting neck mask is free of highly sensitizing and irritating preservatives, thus offering improved safety.

Description

Technical Field

[0001] The invention belongs to the field of neck care, and particularly relates to a composition for reducing neck wrinkles, a neck mask and a preparation method thereof. Background Art

[0002] Skin aging is a prominent external manifestation of human aging. As people age, their metabolism slows, and the number of fibroblasts in the body gradually decreases. The collagen and elastin they secrete also decrease and break down due to oxidation, leading to the loss of these supporting components of the epidermis. This causes uneven collapse of the epidermis, thinning of the dermis, and loss of skin elasticity, leading to dryness, sagging, dullness, and the development of wrinkles.

[0003] The skin on the neck has only one-third the number of sebaceous and sweat glands as the face. Sebum secretion is low, making it difficult to retain moisture and more susceptible to dryness. Furthermore, the skin on the neck is under constant pressure and tension, making it more susceptible to aging, sagging, and wrinkling. Therefore, it requires careful care and maintenance. Transverse neck lines are the earliest clinical manifestation of neck aging and one of its most prominent features. However, unlike other signs of neck aging, such as skin laxity, decreased elasticity, fat pads, and platysma cords, transverse neck lines are not completely correlated with age or photoaging.

[0004] The main mechanisms of neck wrinkles are as follows: 1. Unlike facial skin, the thickness of neck skin is only 2 / 3 that of the face, with fewer sweat and sebaceous glands and less fat content. Therefore, with age, the hydration capacity of the neck skin's stratum corneum decreases, the content of water-fat emulsions on the skin surface decreases, and transepidermal water loss increases, which can lead to dry skin, fine lines, and uneven skin tone. 2. With age, the decrease in cell number and changes in the extracellular matrix (decreased amount and disordered arrangement of dermal collagen fibers and fibroblasts, denaturation and rupture of elastin, and decreased hyaluronic acid content) lead to increased transepidermal water loss and dryness, resulting in wrinkles, increased roughness, and decreased elasticity of the neck skin. 3. The platysma muscle, as the largest depressor muscle of the face and neck, can cause the formation and aggravation of neck wrinkles through its pulling effect. Genetic factors, obesity, and age can also cause the platysma muscle to relax and sag, resulting in uneven distribution, resulting in an aged appearance of the face and neck. 4. The relaxation and sagging of the platysma muscle can easily store fat. The accumulation of fat in the superficial and deep layers of the neck can lead to the formation of a "double chin" and neck wrinkles due to fat accumulation.

[0005] Chinese invention patent application CN110787074A discloses a composition for reducing fine lines. The composition primarily contains a combination of active ingredients, including hydrolyzed yeast extract, wild soybean seed extract, euglena polysaccharide, and royal jelly extract. This composition not only promotes better skin absorption, aids in skin damage repair, nourishes and hydrates the skin, and consolidates the repair effect, but also reduces the proportion of irritants, making the product safer and more reliable. However, the effectiveness of this composition for transverse neck lines is unclear.

[0006] Chinese invention patent application CN114366694A discloses a composition for moisturizing and lightening fine lines and a preparation method thereof, belonging to the technical field of cosmetics. The composition comprises the following raw materials in weight percentage: Phase A: 65-75% solvent, 5-13% moisturizer, 0.2-0.85% antioxidant, 0.02-0.1% chelating agent; Phase B: 5-17% emollient, 1.11-6% emulsifier; Phase C: 0.2-1% emulsion stabilizer, 0.1-0.4% pH adjuster; Phase D: 3.11-18.7% skin conditioner; the sum of the raw materials of Phases A, B, C, and D is 100%. The finally prepared composition for moisturizing and lightening fine lines has moisturizing and emollient effects, but the effect of the composition on lightening neck lines is unclear.

[0007] There are few existing technologies specifically designed to reduce neck wrinkles. Market-wide, neck care often involves applying and massaging the neck alongside facial care products like creams. However, because the skin on the neck is thinner and has fewer sebaceous and sweat glands than the face, it's more susceptible to damage. When consumers apply, massage, and rub their necks with their own hands, rather than using specialized neck massagers, they often incur more damage from external forces. Furthermore, without distinguishing between facial and neck skin, facial care products are often applied directly to the neck. This crude, simplistic approach often results in ineffective neck care. Summary of the Invention

[0008] To address the shortcomings of the prior art, the present invention aims to provide a composition, a neck mask, and a preparation method for reducing neck wrinkles. The composition targets the mechanism of transverse neck wrinkles and effectively reduces them through moisturizing, repairing, and inhibiting mechanisms, resulting in a smoother, firmer, and more supple neck skin.

[0009] In order to achieve the above object, the present invention provides the following technical solutions:

[0010] A composition for reducing neck wrinkles comprises raw materials of: Polygonum multiflorum extract and Polygonum aviculare extract.

[0011] Preferably, the raw materials of the composition further include hydroxypropyltrimethylammonium chloride hyaluronic acid, dipeptide diaminobutyryl benzylamide diacetate and acetyl glucosamine.

[0012] Preferably, the composition comprises the following raw materials in parts by weight: 0.3-1.5 parts of Polygonum multiflorum extract, 0.3-1.5 parts of Cyperus rotundus extract, 0.03-0.15 parts of hydroxypropyltrimonium chloride hyaluronic acid, 0.005-0.03 parts of dipeptide diaminobutyryl benzylamide diacetate and 0.2-3 parts of acetyl glucosamine.

[0013] Further preferably, the composition comprises the following raw materials in parts by weight: 0.5-1 part of Polygonum multiflorum extract, 0.5-1 part of Polygonum multiflorum extract, 0.03-0.1 part of hydroxypropyltrimonium chloride hyaluronic acid, 0.005-0.02 part of dipeptide diaminobutyryl benzylamide diacetate and 0.2-2 parts of acetyl glucosamine.

[0014] Polygonum aviculare extract is an active ingredient extracted from Polygonum aviculare (Polygonum aviculare) grown in the desert areas of central Australia, which are subject to severe photodamage. It can increase skin firmness and reduce the appearance of wrinkles by inhibiting a unique enzyme related to photoaging - cathepsin G, thereby preventing premature photoaging of the skin.

[0015] Gigartina Stellata extract is an extract from red marine macroalgae that has the effect of strengthening the extracellular matrix and restructuring collagen and elastic fibers, restoring skin's softness, firmness and elasticity.

[0016] Hydroxypropyltrimonium chloride hyaluronic acid is a new type of cationic hyaluronic acid made by new biotechnology. It can significantly improve the adhesion of hyaluronic acid to the skin surface. It is more resistant to washing than non-cationized hyaluronic acid. It has timely and cumulative moisturizing effects and effectively improves the moisturizing of the neck skin.

[0017] Dipeptide diaminobutyrylbenzylamide diacetate, also known as snake venom peptide, is a synthetic tripeptide that mimics the activity of the snake venom toxin Waglerin 1. This tripeptide antagonistically binds to acetylcholine receptors, locally blocking the nerves that transmit muscle contraction signals and promoting muscle relaxation. This helps smooth and reduce wrinkles, effectively preventing the development of neck wrinkles caused by the platysma muscle.

[0018] NAG can stimulate the synthesis of collagen in the skin, increase the elasticity and firmness of the skin, thereby reducing the appearance of fine lines; it can also promote the synthesis of hyaluronic acid in keratinocytes, enhance the function of the skin barrier, reduce water loss, and improve the skin's moisturizing and defense capabilities.

[0019] The present invention also relates to the application of the composition in preparing cosmetics.

[0020] The present invention also relates to a neck mask for reducing neck wrinkles. The raw materials of the neck mask include: a chelating agent, a moisturizing agent, a thickener, an emulsifier, a soothing agent, a skin conditioner and a combination of the above.

[0021] Preferably, the chelating agent includes disodium EDTA; the humectant includes glycerin, 1,3-butylene glycol, trehalose, allantoin, polyethylene glycol-8 and 1,2-hexanediol; the thickener includes xanthan gum and carbomer; the emulsifier includes steareth-2 and steareth-21; the emollient includes hydrogenated polydecene; and the skin conditioning agent includes parahydroxyacetophenone and arginine.

[0022] More preferably, the neck mask contains 1.7%-3.7% of the composition by mass.

[0023] Preferably, the neck mask contains, by mass percentage, 0.02%-0.05% of disodium EDTA, 2%-8% of glycerol, 2%-8% of 1,3-butylene glycol, 0.1%-2% of trehalose, 0.05%-0.2% of allantoin, 0.5%-2% of polyethylene glycol-8, 0.4-0.6% of 1,2-hexanediol, 0.1%-0.2% of xanthan gum, 0.05%-0.15% of carbomer, 0.08%-0.1% of steareth-2, 0.15%-0.2% of steareth-21, 1%-2% of hydrogenated polydecene, 0.4%-0.5% of parahydroxyacetophenone and 0.1%-0.18% of arginine.

[0024] The present invention also relates to a method for preparing the above-mentioned neck mask patch, comprising the following steps:

[0025] (1) adding a chelating agent, a moisturizing agent, and a thickener to sub-water, heating, homogenizing, and stirring to obtain a mixture A;

[0026] (2) mixing the emulsifier and the emollient, heating them, dissolving them, and adding them to the mixture A, homogenizing, and stirring to obtain a mixture B;

[0027] (3) cooling the mixture B, adding a skin conditioner, and stirring to obtain a mixture C;

[0028] (4) Cooling the mixture C, adding the composition for reducing neck wrinkles, stirring, cooling, filtering, aging, and canning to obtain the neck mask patch.

[0029] Preferably, the heating temperature in step (1) and step (2) is 80-85°C, the homogenization conditions are vacuum, the homogenization speed is 2000-3500 rpm, the homogenization time is 3-5 min, the stirring speed is 50-60 rpm, and the stirring time is 5-15 min.

[0030] Preferably, in step (3), the temperature is lowered to 55-65°C, the stirring speed is 45-55 rpm, and the stirring time is 5-10 min; in step (4), the temperature is lowered to 30-40°C, the stirring speed is 45-55 rpm, and the stirring time is 5-10 min.

[0031] Compared with the prior art, the present invention has the following beneficial effects:

[0032] (1) The composition for reducing neck wrinkles prepared by the present invention, wherein the components cooperate with each other in a specific ratio, effectively reducing neck wrinkles through mechanisms such as moisturizing, repairing, and inhibiting, making the neck skin delicate and firm;

[0033] (2) The neck mask of the present invention is formulated with a chelating agent, moisturizer, emollient, emulsifier, thickener, and skin conditioner to fully exert the efficacy of the composition for reducing neck wrinkles and promote penetration and absorption;

[0034] (3) The neck mask of the present invention does not contain preservative ingredients with high sensitization rate and high irritation, and has better safety. DETAILED DESCRIPTION

[0035] The technical solutions in the embodiments of the present invention are further clearly described. The described embodiments are only a part of the present invention and are used to explain the present invention, but not to limit the present invention. Therefore, other embodiments obtained by other technicians in this field without creative work all fall within the scope of protection of the present invention.

[0036] Elixir-IR TM ), purchased from IFF–Lucas Meyer Cosmetics; Gravityl TM ), purchased from Givaudan France SAS; hydroxypropyltrimonium chloride hyaluronic acid (Hyaloveil-P), purchased from QP Corporation Fine Chemical Division; trehalose (Trehalose 100), purchased from Hayashibara Co., Ltd.; polyethylene glycol-8 (Polyglykol 400C), purchased from Clariant Chemical Co., Ltd.; xanthan gum ( CG-F), purchased from CP Kelco US, Inc.; Carbomer (TC-Carbomer 380), purchased from Guangzhou Tianci High-tech Materials Co., Ltd.; Stearyl alcohol polyether-2 (SP BRIJ S2 MBAL-PA-(SG)), purchased from Croda Chemicals (Shanghai) Co., Ltd.; Stearyl alcohol polyether-21 (SP BRIJ S21 MBAL-PA-(SG)), purchased from Croda Chemicals (Shanghai) Co., Ltd.; Hydrogenated polydecene (Synfluid PAO 6cSt), purchased from Chevron Phillips Chemical Company LLC.

[0037] The following reagents not otherwise specified are all common reagents and are commercially available.

[0038] Example 1

[0039] A composition for reducing neck wrinkles comprises, by weight, 0.5 parts of Polygonum multiflorum extract, 1 part of Cyperus acanthoides extract, 0.03 parts of hydroxypropyltrimonium chloride hyaluronic acid, 0.005 parts of dipeptide diaminobutyryl benzylamide diacetate, and 0.2 parts of acetyl glucosamine. The composition is obtained by mixing the above ingredients.

[0040] A neck mask patch comprises the following raw materials, calculated by mass percentage: 0.05% disodium EDTA, 4% glycerol, 5% 1,3-butylene glycol, 0.5% trehalose, 0.1% allantoin, 1.5% polyethylene glycol-8, 0.5% 1,2-hexanediol, 0.15% xanthan gum, 0.1% carbomer, 0.08% steareth-21, 0.15% steareth-21, 1.5% hydrogenated polydecene, 0.5% p-hydroxyacetophenone, 0.15% arginine, 0.5% scutellaria baicalensis extract, 1% cyperus acanthoides extract, 0.03% hydroxypropyltrimonium chloride hyaluronic acid, 0.005% dipeptide diaminobutyryl benzylamide diacetate, 0.2% acetyl glucosamine, and the balance water.

[0041] Preparation method of neck mask:

[0042] (1) Disodium EDTA, glycerol, 1,3-butylene glycol, trehalose, allantoin, polyethylene glycol-8, 1,2-hexanediol, xanthan gum, and carbomer were added to water, heated to 82°C, vacuum homogenized at 2000 rpm for 3 minutes, and stirred at 50 rpm for 5 minutes to obtain a mixture A;

[0043] (2) Steareth-2, Steareth-21, and hydrogenated polydecene were mixed and heated to 82° C. to completely dissolve, and then pumped into mixture A. The mixture was homogenized at 3500 rpm in a vacuum for 5 min, and then stirred at 60 rpm for 15 min to obtain mixture B;

[0044] (3) Cooling the mixture B to 60°C, adding p-hydroxyacetophenone and arginine, and stirring at 50 rpm for 5 minutes to obtain a mixture C;

[0045] (4) Cool the mixture C to 35°C, add the extract of Polygonum multiflorum, the extract of Cyperus rotundus, hydroxypropyltrimethylammonium chloride hyaluronic acid, dipeptide diaminobutyryl benzylamide diacetate and acetyl glucosamine, stir at 50 rpm for 5 min, cool to 25°C, test if qualified, filter out the material, age, and can to obtain the neck mask.

[0046] Example 2

[0047] A composition for reducing neck wrinkles comprises, by weight, 1 part of Polygonum multiflorum extract, 0.5 part of Cyperus acanthoides extract, 0.1 part of hydroxypropyltrimonium chloride hyaluronic acid, 0.02 part of dipeptide diaminobutyryl benzylamide diacetate, and 2 parts of acetyl glucosamine. The composition is obtained by mixing the above ingredients.

[0048] A neck mask patch comprises the following raw materials, calculated by mass percentage: 0.05% disodium EDTA, 4% glycerol, 5% 1,3-butylene glycol, 0.5% trehalose, 0.1% allantoin, 1.5% polyethylene glycol-8, 0.5% 1,2-hexanediol, 0.15% xanthan gum, 0.1% carbomer, 0.08% steareth-21, 0.15% hydrogenated polydecene, 0.5% p-hydroxyacetophenone, 0.15% arginine, 1% scutellaria baicalensis extract, 0.5% cyperus acanthoides extract, 0.1% hydroxypropyltrimonium chloride hyaluronic acid, 0.02% dipeptide diaminobutyryl benzylamide diacetate, 2% acetyl glucosamine, and the balance water.

[0049] Preparation method of neck mask:

[0050] (1) Disodium EDTA, glycerol, 1,3-butylene glycol, trehalose, allantoin, polyethylene glycol-8, 1,2-hexanediol, xanthan gum, and carbomer were added to water, heated to 80°C, homogenized under vacuum at 2500 rpm for 3 minutes, and stirred at 55 rpm for 10 minutes to obtain a mixture A;

[0051] (2) Steareth-2, Steareth-21, and hydrogenated polydecene were mixed and heated to 80° C. to completely dissolve, and then pumped into mixture A. The mixture was homogenized at 3000 rpm in a vacuum for 3 min, and then stirred at 50 rpm for 15 min to obtain mixture B;

[0052] (3) Cooling the mixture B to 55°C, adding p-hydroxyacetophenone and arginine, and stirring at 45 rpm for 10 min to obtain a mixture C;

[0053] (4) Cool the mixture C to 30°C, add the extract of Polygonum multiflorum, the extract of Cyperus rotundus, hydroxypropyltrimethylammonium chloride hyaluronic acid, dipeptide diaminobutyryl benzylamide diacetate and acetyl glucosamine, stir at 55 rpm for 5 minutes, cool to 20°C, test if qualified, filter out the material, age, and can to obtain the neck mask.

[0054] Example 3

[0055] A composition for reducing neck wrinkles comprises, by weight, 0.7 parts of Polygonum multiflorum extract, 0.8 parts of Cyperus acanthoides extract, 0.05 parts of hydroxypropyltrimonium chloride hyaluronic acid, 0.015 parts of dipeptide diaminobutyryl benzylamide diacetate, and 0.8 parts of acetyl glucosamine. The composition is obtained by mixing the above ingredients.

[0056] A neck mask patch comprises the following raw materials, calculated by mass percentage: 0.05% disodium EDTA, 4% glycerol, 5% 1,3-butylene glycol, 0.5% trehalose, 0.1% allantoin, 1.5% polyethylene glycol-8, 0.5% 1,2-hexanediol, 0.15% xanthan gum, 0.1% carbomer, 0.08% steareth-21, 0.15% hydrogenated polydecene, 0.5% p-hydroxyacetophenone, 0.15% arginine, 0.7% scutellaria baicalensis extract, 0.8% cyperus acanthoides extract, 0.05% hydroxypropyltrimonium chloride hyaluronic acid, 0.015% dipeptide diaminobutyryl benzylamide diacetate, 0.8% acetyl glucosamine, and the balance water.

[0057] The preparation method of the neck mask is the same as that in Example 1.

[0058] Example 4

[0059] A composition for reducing neck wrinkles comprises, by weight, 0.8 parts of Polygonum multiflorum extract, 0.7 parts of Cyperus acanthoides extract, 0.08 parts of hydroxypropyltrimonium chloride hyaluronic acid, 0.01 parts of dipeptide diaminobutyryl benzylamide diacetate, and 1.5 parts of acetyl glucosamine. The composition is obtained by mixing the above ingredients.

[0060] The raw material ratio of a neck mask is shown in Example 4 in Table 1, and the preparation method is the same as that of Example 1.

[0061] Example 5

[0062] A composition for reducing neck wrinkles comprises, by weight, 0.8 parts of Polygonum multiflorum extract, 0.8 parts of Cyperus rotundus extract, 0.05 parts of hydroxypropyltrimonium chloride hyaluronic acid, 0.02 parts of dipeptide diaminobutyryl benzylamide diacetate, and 1 part of acetyl glucosamine. The composition is obtained by mixing the above ingredients.

[0063] The raw material formula of a neck mask is shown in Example 5 in Table 1.

[0064] Preparation method of neck mask:

[0065] (1) Disodium EDTA, glycerol, 1,3-butylene glycol, trehalose, allantoin, polyethylene glycol-8, 1,2-hexanediol, xanthan gum, and carbomer were added to water, heated to 85°C, homogenized under vacuum at 2500 rpm for 5 minutes, and stirred at 55 rpm for 10 minutes to obtain a mixture A;

[0066] (2) Steareth-2, Steareth-21, and hydrogenated polydecene were mixed and heated to 85° C. to completely dissolve, and then pumped into mixture A. Vacuum homogenization was performed at 3500 rpm for 3 min, and the mixture was stirred at 60 rpm for 10 min to obtain mixture B;

[0067] (3) Cooling the mixture B to 65°C, adding p-hydroxyacetophenone and arginine, and stirring at 55 rpm for 8 minutes to obtain a mixture C;

[0068] (4) Cool the mixture C to 40°C, add the extract of Polygonum multiflorum, the extract of Cyperus rotundus, hydroxypropyltrimethylammonium chloride hyaluronic acid, dipeptide diaminobutyryl benzylamide diacetate and acetyl glucosamine, stir at 45 rpm for 8 min, cool to 25°C, test if qualified, filter out the material, age, and can to obtain the neck mask.

[0069] Example 6

[0070] A composition for reducing neck wrinkles, comprising the same raw materials as those in Example 5.

[0071] A neck mask patch, the raw materials and proportions are shown in Example 6 of Table 1, and the preparation method is the same as that of Example 1.

[0072] Example 7

[0073] A composition for reducing neck wrinkles, comprising the same raw materials as those in Example 5.

[0074] A neck mask patch, the raw materials and proportions are shown in Example 7 of Table 1, and the preparation method is the same as that of Example 1.

[0075] The raw materials and proportions of the neck mask in Examples 1-7 are shown in Table 1.

[0076] Table 1 Raw material components and mass percentages of the neck mask of Examples 1-7

[0077]

[0078] Comparative Example 1

[0079] A composition for reducing neck wrinkles, which differs from Example 5 in that it does not contain the Polygonum multiflorum extract and the mass percentage of the Polygonum multiflorum extract is 1.6%.

[0080] A neck mask patch, the raw materials and proportions are shown in Comparative Example 1 in Table 2.

[0081] The preparation method of the neck mask is the same as that of Example 5, except that the Herba Polygoni Multiflori extract is not added in step (4).

[0082] Comparative Example 2

[0083] A composition for reducing neck wrinkles, which differs from Example 5 in that: it does not contain the Cyperus acutus extract, and the mass percentage of the Polygonum multiflorum extract is 1.6%.

[0084] A neck mask patch, the raw materials and proportions are shown in Comparative Example 2 in Table 2.

[0085] The preparation method of the neck mask is the same as that of Example 5, except that the extract of Ceropegia australis is not added in step (4).

[0086] Comparative Example 3

[0087] A composition for reducing neck wrinkles, which differs from Example 5 in that: hydroxypropyltrimonium chloride hyaluronic acid is not contained, and the mass percentage of acetyl glucosamine is 1.05%.

[0088] A neck mask patch, the raw materials and proportions are shown in Comparative Example 3 in Table 2.

[0089] The preparation method of the neck mask is the same as that of Example 5, except that hydroxypropyltrimethylammonium chloride hyaluronic acid is not added in step (4).

[0090] Comparative Example 4

[0091] A composition for reducing neck wrinkles, which differs from Example 5 in that: it does not contain dipeptide diaminobutyryl benzylamide diacetate, and the mass percentage of acetyl glucosamine is 1.02%.

[0092] A neck mask patch, the raw materials and proportions are shown in Comparative Example 4 in Table 2.

[0093] The preparation method of the neck mask is the same as that of Example 5, except that dipeptide diaminobutyryl benzylamide diacetate is not added in step (4).

[0094] Comparative Example 5

[0095] A composition for reducing neck wrinkles, which differs from Example 5 in that: acetyl glucosamine is not contained, and the mass percentage of Polygonum multiflorum extract is 1.8%.

[0096] A neck mask patch, the raw materials and proportions are shown in Comparative Example 5 in Table 2.

[0097] The preparation method of the neck mask is the same as that of Example 5, except that acetyl glucosamine is not added in step (4).

[0098] The raw materials and proportions of the neck mask patches in Comparative Examples 1-5 are shown in Table 2.

[0099] Table 2 Comparative Examples 1-5 Neck Mask Raw Material Components and Their Mass Percentages

[0100]

[0101]

[0102] Effect test

[0103] Test Example 1: Closed Patch Test

[0104] Volunteer screening and testing requirements: ① Age / gender: 18-60 years old, male or female (excluding pregnant or lactating women); ② Testing site: inner arm; ③ Pay close attention to the testing site during the test and avoid strenuous exercise on the same day. The judging criteria are shown in Table 3.

[0105] Table 3 Evaluation criteria for closed patch test

[0106]

[0107] Result determination: If more than 5 of the 30 subjects had grade 1 adverse skin reactions, or more than 2 had grade 2 adverse skin reactions, or any grade 3 or higher adverse skin reaction occurred, the test substance was determined to have adverse skin reactions in humans.

[0108] The results of the closed patch test are shown in Table 4.

[0109] Table 4 Closed patch test results

[0110]

[0111] Conclusion: The patch results show that Examples 1-7 have no adverse reactions on human skin.

[0112] Test Example 2: Neck wrinkle reduction effect test

[0113] Volunteer screening: 60 volunteers aged 18-35 years, regardless of gender (except women in pregnancy and lactation), with mild, superficial horizontal neck wrinkles on their necks were selected and randomly divided into 12 groups.

[0114] Volunteer satisfaction evaluation method: Satisfaction rate = (number of very satisfied + satisfied) volunteers / total number of volunteers × 100%.

[0115] The evaluation criteria are shown in Table 5.

[0116] Table 5 Evaluation criteria for reducing neck wrinkles

[0117]

[0118]

[0119] The test results of reducing neck wrinkles are shown in Table 6.

[0120] Table 6 Test results of reducing neck wrinkles

[0121]

[0122] Conclusion: The components of the composition for reducing neck wrinkles cooperate with each other in a specific proportion. The neck mask can fully exert the efficacy of the composition for reducing neck wrinkles, effectively reduce neck wrinkles and gain user satisfaction.

[0123] The above detailed description is a specific description of one feasible embodiment of the present invention. This embodiment is not intended to limit the patent scope of the present invention. Any equivalent implementation or modification that does not depart from the present invention should be included in the scope of the technical solution of the present invention.

Claims

1. A composition for reducing neck wrinkles, characterized in that: The composition comprises the following raw materials in parts by weight: 0.3-1.5 parts of Polygonum multiflorum extract, 0.3-1.5 parts of Polygonum multiflorum extract, 0.03-0.15 parts of hydroxypropyltrimonium chloride hyaluronic acid, 0.005-0.03 parts of dipeptide diaminobutyryl benzylamide diacetate and 0.2-3 parts of acetyl glucosamine.

2. The composition according to claim 1, characterized in that The composition comprises the following raw materials in parts by weight: 0.5-1 part of Polygonum multiflorum extract, 0.5-1 part of Polygonum multiflorum extract, 0.03-0.1 part of hydroxypropyltrimonium chloride hyaluronic acid, 0.005-0.02 part of dipeptide diaminobutyryl benzylamide diacetate and 0.2-2 parts of acetyl glucosamine.

3. Use of the composition according to any one of claims 1 to 2 in preparing a cosmetic for reducing neck wrinkles.

4. A neck mask for reducing neck wrinkles, characterized in that: The raw materials of the neck mask include: a chelating agent, a moisturizing agent, a thickener, an emulsifier, a soothing agent, a skin conditioner and the composition according to any one of claims 1 to 2.

5. The neck mask according to claim 4, characterized in that: The chelating agent includes disodium EDTA; the moisturizing agent includes glycerin, 1,3-butylene glycol, trehalose, allantoin, polyethylene glycol-8 and 1,2-hexanediol; the thickening agent includes xanthan gum and carbomer; the emulsifier includes steareth-2 and steareth-21; the emollient includes hydrogenated polydecene; and the skin conditioning agent includes p-hydroxyacetophenone and arginine.

6. The neck mask according to claim 4, characterized in that: Calculated by mass percentage, the neck mask contains 1.7%-3.7% of the composition according to any one of claims 1-2.

7. The neck mask according to claim 5, characterized in that: In terms of mass percentage, the neck mask contains 0.02%-0.05% of disodium EDTA, 2%-8% of glycerol, 2%-8% of 1,3-butylene glycol, 0.1%-2% of trehalose, 0.05%-0.2% of allantoin, 0.5%-2% of polyethylene glycol-8, 0.4-0.6% of 1,2-hexanediol, 0.1%-0.2% of xanthan gum, 0.05%-0.15% of carbomer, 0.08%-0.1% of steareth-2, 0.15%-0.2% of steareth-21, 1%-2% of hydrogenated polydecene, 0.4%-0.5% of p-hydroxyacetophenone and 0.1%-0.18% of arginine.

8. A method for preparing the neck mask according to any one of claims 4 to 7, characterized in that: The following steps are involved: (1) Adding a chelating agent, a humectant, and a thickener to water, heating, homogenizing, and stirring to obtain a mixture A; (2) Mix the emulsifier and the emollient, heat them, dissolve them, add them to the mixture A, homogenize, and stir to obtain the mixture B; (3) Cooling the mixture B, adding a skin conditioner, and stirring to obtain a mixture C; (4) Cooling the mixture C, adding the composition for reducing neck wrinkles, stirring, cooling, filtering, aging, and canning to obtain the neck mask patch.

9. The preparation method according to claim 8, characterized in that The heating temperature in step (1) and step (2) is 80-85° C., the homogenization condition is vacuum, the homogenization speed is 2000-3500 rpm, the homogenization time is 3-5 min, the stirring speed is 50-60 rpm, and the stirring time is 5-15 min.

10. The preparation method according to claim 8, characterized in that In step (3), the temperature is lowered to 55-65°C, the stirring speed is 45-55 rpm, and the stirring time is 5-10 min.

11. The preparation method according to claim 8, characterized in that In step (4), the temperature is lowered to 30-40°C, the stirring speed is 45-55 rpm, and the stirring is carried out for 5-10 minutes.

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