A blood protein polypeptide beverage capable of increasing oxygen carrying capacity

Abstract

The present application relates to the field of beverage technology and specifically discloses a blood protein polypeptide beverage that increases oxygen carrying capacity. The blood protein polypeptide beverage that increases oxygen carrying capacity is mainly made from the following raw materials: blood protein polypeptide microcapsule powder, red date extract, rhodiola rosea powder, red ginseng powder, acerola cherry powder, honeysuckle pollen, collagen peptide powder, taurine, vitamins, acidulant, sweetener, compound thickener, and water; the blood protein polypeptide microcapsule powder is mainly made from the following raw materials: blood protein polypeptide powder, maltitol, modified starch, phospholipids, water, mono- and diglycerol fatty acid esters, 1,3-acetone dicarboxylic acid, and an organic solvent. This blood protein polypeptide beverage that increases oxygen carrying capacity has the advantages of good blood-tonifying effect, high absorption rate, and high safety. It can effectively improve the body's anemia indicators and enhance erythropoiesis.

Description

Technical Field

[0001] The present application relates to the technical field of beverages, and more specifically, to a blood protein polypeptide beverage with improved oxygen carrying capacity. Background Art

[0002] With the accelerating pace of life and increasing work and personal pressures, people's health issues are receiving increasing attention. For those with anemia, peripheral red blood cell volume is reduced, failing to deliver sufficient oxygen to tissues. Clinically, this is often measured by hemoglobin. Normal hemoglobin levels range from 110-150g / L, while those with anemia typically have hemoglobin levels below 110g / L. Symptoms of anemia include pale complexion, fatigue, insomnia, and frequent dreams. Summary of the Invention

[0003] In order to improve anemia indicators, the present application provides a blood protein polypeptide beverage with increased oxygen carrying capacity, which adopts the following technical solution:

[0004] A blood protein polypeptide beverage for improving oxygen carrying capacity, mainly composed of the following raw materials in percentage by weight: 10-15% blood protein polypeptide microcapsule powder, 4-8% red date extract, 1.5-3.5% rhodiola rosea powder, 1.5-3.5% red ginseng powder, 1-2% acerola cherry powder, 1-2% honeysuckle pollen, 0.5-1.5% collagen peptide powder, 0.3-1% taurine, 0.5-1.5% vitamins, 0.2-1% acidulant, 1-3% sweetener, 3-6% compound thickener, and the balance being water;

[0005] The blood protein polypeptide microcapsule powder is mainly prepared from the following raw materials in parts by weight: 4-6 parts of blood protein polypeptide powder, 10-20 parts of maltitol, 3-8 parts of modified starch, 2-4 parts of phospholipids, 80-120 parts of water, 4-6 parts of mono- and diglycerol fatty acid esters, 1-3 parts of 1,3-acetone dicarboxylic acid, and 300-800 parts of organic solvent; the modified starch is obtained by treating starch with octenylsuccinic anhydride and polypropylene imine triamine dendrimer.

[0006] The blood protein polypeptide beverage with improved oxygen carrying capacity of the present application has the advantages of good blood-enriching effect, high absorption rate and high safety. It can effectively improve the body's anemia indicators and enhance the red blood cell production effect. It is suitable for long-term use by people with anemia, for long-term use by people in plateau environments, and for long-term use by athletes.

[0007] Adding blood protein polypeptide microcapsule powder to the raw materials of blood protein polypeptide beverage to improve oxygen carrying capacity, which contains blood protein polypeptide powder, can increase the body's red blood cell count by an average of 0.58×10 12 / L, and an average increase of 19.4g / L in hemoglobin. This not only increases red blood cell count and hemoglobin, but also coats the hemoglobin polypeptide powder to enhance biocompatibility. Simultaneously, through the interaction between the raw materials of the hemoglobin polypeptide microcapsule powder, the average particle size of the hemoglobin polypeptide microcapsule powder is less than 400nm, the mass change rate is less than 1%, and the hemoglobin polypeptide beverage with increased oxygen carrying capacity remains transparent and free of agglomeration even after 30 days of storage. This gives the hemoglobin polypeptide microcapsule powder the characteristics of small particle size, high thermal stability, and good dispersibility.

[0008] Maltitol and modified starch are added to the raw materials of the blood protein polypeptide microcapsule powder. Maltitol contains a large number of hydroxyl groups, and modified starch contains a large number of hydroxyl groups, primary amino groups, and tertiary amino groups. It has excellent film-forming properties and can be used to coat the blood protein polypeptide powder. 1,3-acetone dicarboxylic acid is added to the raw materials. 1,3-acetone dicarboxylic acid contains carboxyl groups and aldehyde groups. The carboxyl groups and aldehyde groups in 1,3-acetone dicarboxylic acid can undergo cross-linking reactions with the hydroxyl groups in maltitol and the hydroxyl groups and primary amino groups in modified starch, greatly increasing the cross-linking density between maltitol and modified starch, reducing the average particle size, and improving thermal stability and dispersibility.

[0009] Optionally, the blood protein polypeptide microcapsule powder is prepared by the following method:

[0010] S1. Mix water, blood protein polypeptide powder, maltitol, modified starch, and lecithin to obtain a premixed solution;

[0011] S2, mixing an organic solvent, mono- and diglycerol fatty acid esters, and 1,3-acetone dicarboxylic acid to obtain a mixed solution;

[0012] S3. Add the premixed liquid to the mixed liquid at a temperature of 50-70° C. and a rotation speed of 400-600 r / min, stir for 20-40 min, then stir at a rotation speed of 4000-6000 r / min for 50-70 min, and then homogenize at a pressure of 50-70 MPa for 1-5 times to obtain a microcapsule emulsion;

[0013] S4. Spray-drying the microcapsule emulsion to obtain blood protein polypeptide microcapsule powder.

[0014] By adopting the above technical solution, the preparation of blood protein polypeptide microcapsule powder is facilitated.

[0015] Optionally, the blood protein polypeptide is one or both of bovine blood protein polypeptide and porcine blood protein polypeptide. Preferably, the blood protein polypeptide is bovine blood protein polypeptide.

[0016] Optionally, the modified starch is prepared by the following method: adding starch to water at a temperature of 60-80°C and mixing, then adding sodium hydroxide solution, stirring for 20-40 minutes, then adding octenylsuccinic anhydride, stirring for 4-6 hours, then adding polypropyleneimine triamine dendrimer, stirring for 23-27 hours, adjusting the pH value to 4-5, cooling, standing for 1-3 hours, filtering, washing, and drying to obtain modified starch.

[0017] Optionally, the weight ratio of the water, starch, sodium hydroxide solution, octenylsuccinic anhydride, and polypropyleneimine triamine dendrimer is (80-120):(35-45):(4-8):(3-5):(1-2), and the mass concentration of sodium hydroxide in the sodium hydroxide solution is 5-15%.

[0018] By adopting the above technical solution, sodium hydroxide is used to destroy some hydrogen bonds in starch, reducing the interaction between starch molecules and causing starch gelatinization. Octenylsuccinic anhydride is added, and its anhydride is hydrolyzed to form two carboxyl groups. The carboxyl groups and the hydroxyl groups on the starch surface undergo an esterification reaction to achieve grafting and introduce carbon-carbon double bonds. Polypropylene imine triamine dendrimer is added, which contains four primary amine groups and two tertiary amine groups. The primary amine groups and the carbon-carbon double bonds on the starch surface undergo an addition reaction to achieve grafting and introduce primary and tertiary amine groups, greatly increasing the number of starch surface groups and the amount of branches, enhancing the crosslinking density of modified starch and maltitol, reducing the average particle size, improving thermal stability and dispersibility, and also increasing the storage stability of the blood protein polypeptide beverage with increased oxygen carrying capacity.

[0019] Optionally, the starch is one or more of corn starch, wheat starch, potato starch, and tapioca starch.

[0020] By adopting the above technical solution, the source of starch is limited, which facilitates the selection of starch, and the source is abundant, easy to obtain, safe and stable.

[0021] Optionally, the phospholipid is one or more of lecithin, cephalin, phosphatidylserine, and phosphatidylglycerol, and the organic solvent is one or more of palm oil, olive oil, coconut oil, peanut oil, and rapeseed oil.

[0022] By adopting the above technical solution, the sources of phospholipids and organic solvents are limited, which facilitates the selection of phospholipids and organic solvents, and the sources are abundant, easy to obtain, safe and stable.

[0023] Optionally, the lecithin is one or more of soybean lecithin, egg yolk lecithin, and fish oil lecithin. Preferably, the lecithin is soybean lecithin.

[0024] Optionally, the specific gravity of the red date extract is 1.0-1.3.

[0025] Specific gravity, also known as relative density, is the ratio of the density of red date extract to the density of water. Because red date extract contains both red date extract and water, its density is greater than that of water. Limiting the specific gravity of red date extract, and therefore the concentration of red date extract in the red date extract, not only facilitates the selection of red date extracts, but also increases their nutritional content and ensures the uniformity of the blood protein peptide beverage, which increases oxygen carrying capacity.

[0026] Optionally, the vitamin is one or more of vitamin C, vitamin B1, vitamin B6, vitamin B12, folic acid, and niacinamide.

[0027] By adopting the above technical solution, the source of vitamins is limited, which facilitates the selection of vitamins. In addition, vitamin C, vitamin B1, vitamin B6, vitamin B12, folic acid, and niacinamide all have excellent water solubility, ensuring the uniformity of the blood protein polypeptide beverage with increased oxygen carrying capacity.

[0028] Optionally, the collagen peptide powder is one or more of fish collagen peptide, bovine bone collagen peptide, and sheep spleen collagen peptide. Preferably, the collagen peptide powder is fish collagen peptide.

[0029] Optionally, the acidulant is one or more of citric acid, malic acid, lactic acid, and tartaric acid, and the sweetener is one or more of sorbitol, steviol glycoside, and erythritol.

[0030] By adopting the above technical solution, the sources of the acidulant and the sweetener are limited, which facilitates the selection of the acidulant and the sweetener, and the sources are abundant and easily available.

[0031] Optionally, the sweeteners are sorbitol, steviol glycosides, and erythritol, and the weight ratio of sorbitol, steviol glycosides, and erythritol is (4-6):(2-4):(1-3). In multiple embodiments, the weight ratio of sorbitol, steviol glycosides, and erythritol is 5:3:2, and the weight ratio can also be set to 4:2:1, 4:2:3, 4:4:1, 4:4:3, 6:2:1, 6:2:3, 6:4:1, 6:4:3, etc. as needed.

[0032] Optionally, the compound thickener is mainly made of the following raw materials in parts by weight: 22-34 parts of tremella polysaccharide, 20-30 parts of maltodextrin, 20-30 parts of α-cyclodextrin, 5-15 parts of sodium carboxymethyl cellulose, 3-7 parts of agar, 3-7 parts of xanthan gum, and 1-3 parts of sodium citrate.

[0033] By adopting the above technical solution, the raw materials and raw material ratios of the compound thickener are optimized, which can not only increase the viscosity of the blood protein polypeptide beverage with increased oxygen carrying capacity, but also improve the thickening effect and expand the scope of application.

[0034] In summary, this application has at least the following beneficial effects:

[0035] 1. The blood protein polypeptide beverage with improved oxygen carrying capacity of the present application has the advantages of good blood-enriching effect, high absorption rate and high safety. It can effectively improve the body's anemia indicators and enhance the red blood cell production effect. It is suitable for long-term use by people with anemia, people living in plateau environments, and athletes.

[0036] 2. The blood protein polypeptide microcapsule powder of the present application has maltitol and modified starch added to the raw materials, which can coat the blood protein polypeptide powder. 1,3-acetone dicarboxylic acid is also added, which can increase the cross-linking density between maltitol and modified starch, and make the average particle size of the blood protein polypeptide microcapsule powder less than 400nm and the mass change rate less than 1%. The blood protein polypeptide beverage with increased oxygen carrying capacity remains transparent and free of agglomeration after storage for 30 days, and the blood protein polypeptide microcapsule powder has the characteristics of small particle size, high thermal stability and good dispersibility. DETAILED DESCRIPTION

[0037] To make this application easier to understand, the following examples will be used to further illustrate this application. These examples are for illustrative purposes only and are not intended to limit the scope of application of this application. Unless otherwise specified, the raw materials or components used in this application can be obtained through commercial channels or conventional methods.

[0038] Preparation Example

[0039] Table 1 Amount of each raw material of blood protein polypeptide microcapsule powder (unit: g)

[0040] Preparation Example Preparation Example 1 Preparation Example 2 Preparation Example 3 Blood protein peptide powder 5 4 6 Maltitol 15 10 20 modified starch 5 8 3 phospholipids 3 2 4 water 100 80 120 Mono- and diglycerol fatty acid esters 5 6 4 1,3-Acetonedicarboxylic acid 2 3 1 organic solvents 500 300 800

[0041] Preparation Example I-1

[0042] A blood protein polypeptide microcapsule powder, the raw materials and raw material ratios of which are shown in Table 1.

[0043] Among them, the blood protein polypeptide is bovine blood protein peptide, and is selected from Xi'an Wanlv Biotechnology Co., Ltd.; the phospholipid is lecithin, and the lecithin is soybean lecithin; the mono- and diglycerol fatty acid esters are selected from Hebei Baipin Biotechnology Co., Ltd.; the organic solvent is palm oil, and is selected from Shandong Jinmei Chemical Co., Ltd.; the modified starch is obtained by treating starch with octenylsuccinic anhydride and polypropyleneimine triamine dendrimer, and the starch is corn starch, and is selected from Hebei Baipin Biotechnology Co., Ltd.

[0044] A method for preparing blood protein polypeptide microcapsule powder comprises the following steps:

[0045] S0. Prepare modified starch, and the modified starch is prepared by the following method:

[0046] Starch was added to water at 70°C and stirred for 5 minutes. A 10% sodium hydroxide solution was then added and stirred for 30 minutes. Octenylsuccinic anhydride was then added and stirred for 5 hours. Polypropylene imine triamine dendrimer was then added and stirred for 25 hours. The pH was adjusted to 4.5 using a 10% hydrochloric acid solution, the temperature was lowered to 25°C, and the mixture was allowed to stand for 2 hours. The mixture was then filtered, washed three times with water, and dried to obtain the modified starch.

[0047] The weight ratio of water, starch, sodium hydroxide solution, octenylsuccinic anhydride and polypropyleneimine triamine dendrimer is 100:40:6:4:1.4.

[0048] S1. Add blood protein polypeptide powder, maltitol, modified starch, and lecithin to water at 60° C. and stir for 5 minutes to obtain a premixed solution.

[0049] S2. Add mono- and diglycerol fatty acid esters and 1,3-acetone dicarboxylic acid to an organic solvent at a temperature of 60° C., mix, and stir for 2 minutes to obtain a mixed solution.

[0050] S3. Add the premixed solution to the mixed solution at a temperature of 60°C and a rotation speed of 500 r / min, and stir for 30 minutes. Then, stir at a rotation speed of 5000 r / min for 60 minutes. Then, homogenize twice at a pressure of 60 MPa to obtain a microcapsule emulsion.

[0051] S4. Spray-drying the microcapsule emulsion to obtain blood protein polypeptide microcapsule powder.

[0052] Preparation Example I-2

[0053] A blood protein polypeptide microcapsule powder is different from Preparation Example 1 in that the raw material ratio of the blood protein polypeptide microcapsule powder is different, and the raw material ratio is shown in Table 1.

[0054] Preparation Example I-3

[0055] A blood protein polypeptide microcapsule powder is different from Preparation Example 1 in that the raw material ratio of the blood protein polypeptide microcapsule powder is different, and the raw material ratio is shown in Table 1.

[0056] Preparation Example II-1

[0057] A compound thickener is prepared from the following raw materials: 28g of tremella polysaccharide, 25g of maltodextrin, 25g of alpha-cyclodextrin, 10g of sodium carboxymethyl cellulose, 5g of agar, 5g of xanthan gum, and 2g of sodium citrate.

[0058] Among them, Tremella polysaccharide is selected from Xi'an Anao Biotechnology Co., Ltd.; maltodextrin, α-cyclodextrin, sodium carboxymethyl cellulose, agar, and xanthan gum are all selected from Hebei Baipin Biotechnology Co., Ltd.

[0059] A method for preparing a compound thickener comprises the following steps:

[0060] Maltodextrin, α-cyclodextrin, sodium carboxymethyl cellulose, agar, xanthan gum and sodium citrate were added to Tremella polysaccharide and stirred for 2 minutes to obtain a compound thickener.

[0061] Example

[0062] Table 2 Amount of each raw material used in blood protein polypeptide beverages with improved oxygen carrying capacity (unit: × 10 g)

[0063] Example Example 1 Example 2 Example 3 Blood protein polypeptide microcapsule powder 14.36 10 15 Red date extract 6 8 4 Rhodiola rosea powder 2.5 3.5 1.5 Red Ginseng Powder 2.5 1.5 3.5 Acerola powder 1.3 1 2 Honeysuckle pollen 1.3 1 2 Collagen peptide powder 1 1.5 0.5 Taurine 0.57 1 0.3 vitamins 1 0.5 1.5 acidulant 0.45 0.2 1 sweeteners 2.2 3 1 Compound thickener 4.54 3 6 water 62.28 65.8 61.7 total 100 100 100

[0064] Example 1

[0065] A blood protein polypeptide beverage with improved oxygen carrying capacity, the raw materials and raw material ratios of which are shown in Table 2.

[0066] Among them, the specific gravity of red date extract is 1.2, and it is selected from Ningxia Vanilla Biotechnology Co., Ltd.; Rhodiola rosea powder is Rhodiola rosea extract, red ginseng powder is red ginseng extract, acerola cherry powder is acerola cherry extract, and honeysuckle powder is honeysuckle extract, and they are all selected from Xi'an Ruierli Bioengineering Co., Ltd.; collagen peptide powder is fish collagen peptide, and is selected from Xi'an Wanlv Biotechnology Co., Ltd.; vitamin is vitamin B6; the acidulant is citric acid; blood protein polypeptide microcapsule powder is prepared by the method of Preparation Example I-1; the compound thickener is prepared by the method of Preparation Example II-1.

[0067] The sweeteners are sorbitol, steviol glycosides and erythritol, and the weight ratio of sorbitol, steviol glycosides and erythritol is 5:3:2.

[0068] A method for preparing a blood protein polypeptide beverage with improved oxygen carrying capacity comprises the following steps:

[0069] Blood protein polypeptide microcapsule powder, red date extract, rhodiola rosea powder, red ginseng powder, acerola powder, honeysuckle powder, collagen peptide powder, taurine, vitamins, acidulant, sweetener, and compound thickener are added to water and stirred for 5 minutes to obtain a blood protein polypeptide beverage with improved oxygen carrying capacity.

[0070] Example 2

[0071] A blood protein polypeptide beverage with improved oxygen carrying capacity is different from Example 1 in that the raw material ratio of the blood protein polypeptide beverage with improved oxygen carrying capacity is different, and the raw material ratio is shown in Table 2.

[0072] Example 3

[0073] A blood protein polypeptide beverage with improved oxygen carrying capacity is different from Example 1 in that the raw material ratio of the blood protein polypeptide beverage with improved oxygen carrying capacity is different, and the raw material ratio is shown in Table 2.

[0074] Example 4

[0075] A blood protein polypeptide beverage with improved oxygen carrying capacity, which differs from Example 1 in that the raw materials of the blood protein polypeptide beverage with improved oxygen carrying capacity include blood protein polypeptide microcapsule powder from different sources, and the blood protein polypeptide microcapsule powder is prepared using the method of Preparation Example I-2.

[0076] Example 5

[0077] A blood protein polypeptide beverage with improved oxygen carrying capacity, which differs from Example 1 in that the raw materials of the blood protein polypeptide beverage with improved oxygen carrying capacity include blood protein polypeptide microcapsule powder from different sources, and the blood protein polypeptide microcapsule powder is prepared using the method of Preparation Example I-3.

[0078] Comparative Example

[0079] Comparative Example 1

[0080] A blood protein polypeptide beverage with improved oxygen carrying capacity is different from Example 1 in that the raw materials of the blood protein polypeptide beverage with improved oxygen carrying capacity are replaced by an equal amount of water.

[0081] Comparative Example 2

[0082] A blood protein polypeptide beverage with improved oxygen carrying capacity is different from Example 1 in that 25g of blood protein polypeptide powder is used to replace blood protein polypeptide microcapsule powder in the raw materials of the blood protein polypeptide beverage with improved oxygen carrying capacity.

[0083] Comparative Example 3

[0084] A blood protein polypeptide beverage with improved oxygen carrying capacity is different from Example 1 in that an equal amount of maltitol is used to replace modified starch in the blood protein polypeptide microcapsule powder of the blood protein polypeptide beverage raw material for improving oxygen carrying capacity.

[0085] Comparative Example 4

[0086] A blood protein polypeptide beverage with improved oxygen carrying capacity is different from Example 1 in that an equal amount of modified starch is used to replace maltitol in the blood protein polypeptide microcapsule powder of the blood protein polypeptide beverage raw material for improving oxygen carrying capacity.

[0087] Comparative Example 5

[0088] A blood protein polypeptide beverage with improved oxygen carrying capacity is different from Example 1 in that an equal amount of organic solvent is used to replace 1,3-acetone dicarboxylic acid in the blood protein polypeptide microcapsule powder of the blood protein polypeptide beverage raw material for improving oxygen carrying capacity.

[0089] Comparative Example 6

[0090] A blood protein polypeptide beverage with improved oxygen carrying capacity is different from Example 1 in that an equal amount of starch is used to replace modified starch in the blood protein polypeptide microcapsule powder of the blood protein polypeptide beverage raw material for improving oxygen carrying capacity.

[0091] Comparative Example 7

[0092] A blood protein polypeptide beverage with improved oxygen carrying capacity is different from Example 1 in that an equal amount of octenylsuccinic anhydride is used to replace polypropylene imine triamine dendrimer in the preparation of modified starch in the blood protein polypeptide microcapsule powder of the blood protein polypeptide beverage raw material for improving oxygen carrying capacity.

[0093] Comparative Example 8

[0094] A blood protein polypeptide beverage with improved oxygen carrying capacity is different from Example 1 in that an equal amount of polypropylene imine triamine dendrimer is used to replace octenyl succinic anhydride in the preparation of modified starch in the blood protein polypeptide microcapsule powder of the blood protein polypeptide beverage raw material for improving oxygen carrying capacity.

[0095] Performance testing

[0096] (1) The blood protein polypeptide microcapsule powders obtained in Preparation Examples I-1 to I-3 were respectively taken as samples, and toxicology tests and human safety tests were performed on the samples. After testing, the blood protein polypeptide microcapsule powders obtained in Preparation Examples I-1 to I-3 all met the "National Food Safety Standards".

[0097] (2) People aged 40-60 were selected as the research subjects. They took the blood protein polypeptide beverages with improved oxygen carrying capacity obtained in Example 1, Comparative Example 1, and Comparative Example 2 for 30 days, and the red blood cell count and hemoglobin were tested before and after taking the beverage. The comparison results before and after taking the beverage are shown in Table 3.

[0098] The normal value of red blood cell count is 3.6-5.1×10 12 / L, the normal value of hemoglobin is 110-150g / L.

[0099] Table 3 Comparison of effects before and after taking

[0100]

[0101]

[0102] As can be seen from Table 3, the average red blood cell count before taking the blood protein polypeptide beverage with improved oxygen carrying capacity of the present application is 3.16×10 12 / L, the average hemoglobin was 96.5g / L, and the average red blood cell count after taking it was 3.74×10 12 / L, and the average hemoglobin level was 115.9g / L. The average red blood cell count increased by 0.58×10 12 / L, and hemoglobin increased by an average of 19.4g / L. The blood protein polypeptide beverage with improved oxygen carrying capacity of the present application has the advantages of good blood-enriching effect, high absorption rate and high safety through the mutual cooperation between the raw materials. It can effectively improve anemia indicators for anemic constitutions and significantly improve the effect of red blood cell production. At the same time, it can also be taken long-term and continuously.

[0103] (3) The blood protein polypeptide microcapsule powder used in the raw materials of the blood protein polypeptide beverage with improved oxygen carrying capacity of Examples 1 to 5 and Comparative Examples 3 to 8 were respectively taken as samples, and the following performance tests were performed on the samples. The test results are shown in Table 4.

[0104] The mass change rate is determined by the following method: the hemoprotein polypeptide microcapsule powder is left to stand at 50°C for 30 days. The weight before and after standing is measured, and the mass change rate is calculated. The smaller the mass change rate, the better the thermal stability of the hemoprotein polypeptide microcapsule powder.

[0105] (4) The blood protein polypeptide beverages with enhanced oxygen carrying capacity obtained in Examples 1 to 5 and Comparative Examples 3 to 8 were respectively taken as samples, and the following performance tests were performed on the samples. The test results are shown in Table 4.

[0106] The storage stability is tested by the following method: the blood protein polypeptide beverage with enhanced oxygen carrying capacity is placed at a temperature of 50° C. for 30 days to observe whether the blood protein polypeptide beverage with enhanced oxygen carrying capacity becomes turbid or coagulated.

[0107] Table 4 Test results

[0108]

[0109] As can be seen in Table 4, the blood protein polypeptide microcapsule powder of the present application has an average particle size of less than 400 nm and a mass change rate of less than 1%, demonstrating the advantages of small particle size and high thermal stability. Furthermore, the blood protein polypeptide beverage with enhanced oxygen-carrying capacity remained transparent and free of agglomeration after 30 days of storage. This not only enhances the storage stability of the blood protein polypeptide beverage with enhanced oxygen-carrying capacity, but also demonstrates excellent dispersibility of the blood protein polypeptide microcapsule powder.

[0110] Comparing Example 1 with Comparative Examples 3-4, Comparative Example 3 uses maltitol in the raw material for the blood protein polypeptide microcapsule powder; Comparative Example 4 uses modified starch in the raw material for the blood protein polypeptide microcapsule powder; and Example 1 uses both maltitol and modified starch in the raw material for the blood protein polypeptide microcapsule powder. This demonstrates that the simultaneous addition of maltitol and modified starch to the raw material for the blood protein polypeptide microcapsule powder, and the synergistic effect of the two, can reduce the particle size of the blood protein polypeptide microcapsule powder and increase its thermal stability. Furthermore, comparing Example 1 with Comparative Example 5 demonstrates that the use of 1,3-acetonedicarboxylic acid in the raw material for the blood protein polypeptide microcapsule powder increases the crosslinking density and stability between maltitol and modified starch, thereby improving the performance of the blood protein polypeptide microcapsule powder.

[0111] Comparing Example 1 with Comparative Examples 6-8, Comparative Example 6 used starch as the raw material for the blood protein polypeptide microcapsule powder; Comparative Example 7 used starch modified with octenylsuccinic anhydride as the raw material for the blood protein polypeptide microcapsule powder; Comparative Example 8 used starch modified with polypropyleneiminetriamine dendrimer as the raw material for the blood protein polypeptide microcapsule powder; and Example 1 used starch modified with octenylsuccinic anhydride and polypropyleneiminetriamine dendrimer as the raw material for the blood protein polypeptide microcapsule powder. This demonstrates that the simultaneous addition of octenylsuccinic anhydride and polypropyleneiminetriamine dendrimer to the modified starch raw material, and the synergistic effect between the two, can result in improved performance of the modified starch.

[0112] It should be noted that the embodiments described above are only used to explain the present application and do not constitute any limitation to the present application. The present application has been described with reference to typical embodiments, but it should be understood that the words used therein are descriptive and explanatory words, rather than restrictive words. The present application may be modified as specified within the scope of the claims of the present application, and the invention may be revised without departing from the scope and spirit of the present application. Although the present application described therein relates to specific methods, materials and embodiments, it does not mean that the present application is limited to the specific examples disclosed therein. On the contrary, the present application can be extended to all other methods and applications with the same function.

Claims

1. A blood protein polypeptide beverage for increasing oxygen carrying capacity, characterized by: The invention is mainly prepared from the following raw materials in percentage by weight: 10-15% of blood protein polypeptide microcapsule powder, 4-8% of red date extract, 1.5-3.5% of rhodiola rosea powder, 1.5-3.5% of red ginseng powder, 1-2% of acerola cherry powder, 1-2% of honeysuckle powder, 0.5-1.5% of collagen peptide powder, 0.3-1% of taurine, 0.5-1.5% of vitamins, 0.2-1% of acidulant, 1-3% of sweetener, 3-6% of compound thickener, and the balance of water. The blood protein polypeptide microcapsule powder is mainly made of the following raw materials in parts by weight: 4-6 parts of blood protein polypeptide powder, 10-20 parts of maltitol, 3-8 parts of modified starch, 2-4 parts of phospholipids, 80-120 parts of water, 4-6 parts of mono- and diglycerol fatty acid esters, 1-3 parts of 1,3-acetone dicarboxylic acid, and 300-800 parts of organic solvent; the modified starch is obtained by treating starch with octenyl succinic anhydride and polypropylene imine triamine dendrimer; The blood protein polypeptide microcapsule powder is prepared by the following method: S1. Mix water, blood protein polypeptide powder, maltitol, modified starch, and lecithin to obtain a premixed solution; S2, mixing an organic solvent, mono- and diglycerol fatty acid esters, and 1,3-acetone dicarboxylic acid to obtain a mixed solution; S3. Add the premixed liquid to the mixed liquid at a temperature of 50-70° C. and a rotation speed of 400-600 r / min, stir for 20-40 min, then stir at a rotation speed of 4000-6000 r / min for 50-70 min, and then homogenize at a pressure of 50-70 MPa for 1-5 times to obtain a microcapsule emulsion; S4, spray drying the microcapsule emulsion to obtain blood protein polypeptide microcapsule powder; The modified starch is prepared by the following method: adding starch to water at a temperature of 60-80° C. and mixing, then adding sodium hydroxide solution, stirring for 20-40 minutes, then adding octenylsuccinic anhydride, stirring for 4-6 hours, then adding polypropylene imine triamine dendrimer, stirring for 23-27 hours, adjusting the pH value to 4-5, cooling, standing for 1-3 hours, filtering, washing, and drying to obtain the modified starch; The weight ratio of the water, starch, sodium hydroxide solution, octenylsuccinic anhydride and polypropyleneimine triamine dendrimer is (80-120):(35-45):(4-8):(3-5):(1-2), and the mass concentration of sodium hydroxide in the sodium hydroxide solution is 5-15%.

2. The blood protein polypeptide beverage for improving oxygen carrying capacity according to claim 1, characterized in that: The starch is one or more of corn starch, wheat starch, potato starch and tapioca starch.

3. The blood protein polypeptide beverage for improving oxygen carrying capacity according to claim 1, characterized in that: The phospholipid is one or more of lecithin, cephalin, phosphatidylserine, and phosphatidylglycerol, and the organic solvent is one or more of palm oil, olive oil, coconut oil, peanut oil, and rapeseed oil.

4. The blood protein polypeptide beverage for improving oxygen carrying capacity according to claim 1, characterized in that: The specific gravity of the red date extract is 1.0-1.

3.

5. The blood protein polypeptide beverage for improving oxygen carrying capacity according to claim 1, characterized in that: The vitamins are one or more of vitamin C, vitamin B1, vitamin B6, vitamin B12, folic acid, and niacinamide.

6. The blood protein polypeptide beverage for improving oxygen carrying capacity according to claim 1, characterized in that: The acidulant is one or more of citric acid, malic acid, lactic acid, and tartaric acid; the sweetener is one or more of sorbitol, steviol glycoside, and erythritol.

7. The blood protein polypeptide beverage for improving oxygen carrying capacity according to claim 1, characterized in that: The compound thickener is mainly prepared from the following raw materials in parts by weight: 22-34 parts of tremella polysaccharide, 20-30 parts of maltodextrin, 20-30 parts of α-cyclodextrin, 5-15 parts of sodium carboxymethyl cellulose, 3-7 parts of agar, 3-7 parts of xanthan gum, and 1-3 parts of sodium citrate.

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