A traditional Chinese medicine composition for treating non-infectious uveitis of heat-toxin invading collaterals syndrome, traditional Chinese medicine preparation and application thereof

By combining traditional Chinese medicine with Western medicine to treat non-infectious uveitis, and by optimizing the Simiao Yong'an Decoction formula using the theory of collaterals, the problem of poor efficacy of Western medicine was solved, and the effects of reducing recurrence rate, alleviating side effects and accelerating vision recovery were achieved.

CN118615366BActive Publication Date: 2026-01-27XIYUAN HOSPITAL OF CHINA ACAD OF CHINESE MEDICAL SCI
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Patent Information

Application Number
CN202410800732.2
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-06-20
Publication Date
2026-01-27
Estimated Expiration
2044-06-20

AI Technical Summary

Technical Problem

The efficacy and adverse reaction control of existing Western medicine treatments for non-infectious uveitis are not ideal, especially for patients with complex and refractory uveitis. Long-term medication brings economic burden and side effects. The combined use of traditional Chinese medicine based on syndrome differentiation has not yet fully realized its potential.

Method used

This invention provides a traditional Chinese medicine composition for treating non-infectious uveitis caused by heat toxin entering the collaterals. The composition includes honeysuckle, scrophularia, angelica, red peony root, achyranthes root, rehmannia root, and tangerine peel. Based on the theory of collateral diseases, it clears heat, detoxifies, and unblocks the collaterals. Combined with basic Western medicine treatment, the Si Miao Yong An Decoction is optimized to enhance its blood-cooling and blood-activating effects. It is prepared into various dosage forms such as granules.

Benefits of technology

It effectively treats non-infectious uveitis, reduces recurrence rate, alleviates hormone side effects, accelerates vision recovery, relieves eye symptoms, improves patient symptoms, and reduces the toxic side effects of Western medicine hormones.

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Abstract

The application discloses a traditional Chinese medicine composition for treating non-infectious uveitis of heat-toxin entering collaterals syndrome and a traditional Chinese medicine preparation and application thereof. According to weight parts, raw medicinal materials of the traditional Chinese medicine composition include 6-30 parts of honeysuckle, 9-30 parts of figwort, 6-20 parts of angelica, 2-10 parts of raw licorice, 6-15 parts of red peony root, 3-10 parts of chuanxiong rhizome, 5-15 parts of radix paeoniae alba, 6-20 parts of radix rehmanniae recens and 3-15 parts of dried tangerine or orange peel. Based on the theory of collaterals disease, the traditional Chinese medicine composition provided by the application is used for treating non-infectious uveitis of heat-toxin entering collaterals syndrome with heat-clearing, detoxifying and collaterals-unblocking as a basic rule. When the traditional Chinese medicine composition is combined with basic western medicine for treating non-infectious uveitis, the traditional Chinese medicine composition can not only effectively treat non-infectious uveitis and reduce the recurrence rate of non-infectious uveitis within 6 months, but also accelerate the relief of eye symptoms, accelerate the recovery of eyesight and reduce the toxic side effects of combined hormone medication.
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