Incubation plate, incubation bin, incubation device and sample analyzer

The incubation tray with a detection mechanism and optical couplers automates the transfer of reaction cups from the measuring to the cleaning area, addressing inefficiencies in cup cleaning during shutdowns and enhancing machine efficiency.

CN119125524APending Publication Date: 2024-12-13GETEIN BIOTECH
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Patent Information

Application Number
CN202310695965.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2023-06-13
Publication Date
2024-12-13

AI Technical Summary

Technical Problem

Existing sample analyzers face inefficiencies in cup cleaning processes when power outages or misoperations cause shutdowns, requiring manual or universal cleaning of reaction cups, which is cumbersome and time-consuming.

Method used

An incubation tray with a cup measuring area and a cup cleaning area, equipped with a detection mechanism using reflective optical couplers to identify and automatically transfer reaction cups from the measuring area to the cleaning area during restarts.

Benefits of technology

Enhances cup cleaning efficiency by automating the detection and removal of reaction cups, improving overall machine detection efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention belongs to the field of medical instruments, and particularly relates to an incubation tray, an incubation bin, an incubation device and a sample analyzer. The incubation disc comprises a rotating disc, a plurality of cup positions and a detection mechanism, wherein a cup detection area and a cup cleaning area are arranged above the rotating disc; the cup position is arranged on the incubation plate and is used for accommodating the reaction cup; the detection mechanism is arranged on one side of the cup position rotating to the cup detection area. The incubation bin, the incubation device and the sample analyzer all comprise the incubation plate. The cup detection area and the cup cleaning area are arranged above the incubation disc, the detection mechanism is arranged on one side of the cup position at the cup detection area, the detection mechanism is used for detecting whether the reaction cups exist in the cup detection area, if yes, the incubation disc carries the reaction cups at the cup detection area to rotate to the cup cleaning area, and the reaction cups are cleaned away from the cup cleaning area; therefore, the cup cleaning efficiency is effectively improved when the incubation plate is shut down and restarted.
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Description

Technical Field

[0001] The present invention belongs to the field of medical devices, and in particular relates to an incubation tray, an incubation chamber, an incubation device and a sample analyzer. Background Art

[0002] The sample analyzer is used to quantitatively or qualitatively detect antibodies, antigens, enzymes and other substances in the reaction cup. It usually causes the liquid in the reaction cup to undergo a specific reaction. During the reaction, a specific temperature is required to catalyze the reaction. The incubation device can perform this task, so the incubation device is an important component of the sample analyzer.

[0003] During the operation of the sample analyzer, if the entire machine suddenly stops due to power outage or misoperation, when the power system is normal or the operation is corrected, before the sample analyzer can be restarted, it is necessary to take out the reaction cup built into the incubator before the shutdown, and start the program to transport a new reaction cup into the incubator. Currently, manual cup cleaning is commonly used, or the clamp is used to clean all cup positions in the incubator, regardless of whether there is a reaction cup or not. Both solutions are cumbersome and time-consuming, which is not conducive to the overall machine detection efficiency. Summary of the invention

[0004] In view of the deficiencies in the prior art, the present invention discloses an incubation tray, an incubation chamber, an incubation device and a sample analyzer to solve the problem of low cup cleaning efficiency when the incubation tray is shut down and restarted.

[0005] In a first aspect, the present invention discloses an incubation tray, comprising: The turntable has a cup measuring area and a cup cleaning area on top; A plurality of cup positions are arranged on the incubation tray and are used to accommodate reaction cups; The detection mechanism is arranged on one side of the cup position rotated to the measuring cup area, and is used to detect whether the reaction cup exists in the cup position rotated to the measuring cup area when the incubation plate is stopped and restarted. If yes, the incubation plate rotates the reaction cup in the measuring cup area to the cup cleaning area for taking out the reaction cup.

[0006] In some technical solutions, the detection mechanism includes a plurality of detection units, and the detection units correspond one-to-one to the cup positions rotated into the measuring cup area.

[0007] In some technical solutions, the detection unit includes: Mounting bracket; An optical coupling plate, mounted on the mounting bracket; An optical coupler is connected to the optical coupler board.

[0008] In some technical solutions, the optical coupler is a reflective optical coupler.

[0009] In some technical solutions, the distance between the optical coupler and the outer side of the cup edge of the reaction cup at the corresponding cup position is 2-3 mm.

[0010] In some technical solutions, more than two circles of cup positions are arranged circumferentially on the turntable.

[0011] In some technical solutions, the adjacent cup positions between each circle layer are staggered.

[0012] In a second aspect, the present invention discloses an incubation chamber, comprising: The upper end of the shell is an open structure; An incubation tray as described in the first aspect is arranged in the housing.

[0013] In some technical solutions, the incubation chamber also includes an incubation cover, which is arranged above the shell.

[0014] In some technical solutions, a cup cleaning hole is provided on the incubation cover corresponding to the cup cleaning area for taking out the reaction cup.

[0015] In a third aspect, the present invention discloses an incubation device, comprising: The incubation chamber as described in the second aspect, A base assembly, used to support the incubation chamber; A heating component is installed at the bottom of the incubation tray and is used to heat and incubate the reaction cups at each cup position on the incubation tray; A driving assembly is connected to the incubation tray and is used to drive the incubation tray to rotate.

[0016] In a fourth aspect, the present invention discloses a sample analyzer, the sample analyzer comprising: The incubation tray as described in the first aspect, the incubation chamber as described in the second aspect, or the incubation device as described in the third aspect; The clamp is used to clamp the reaction cup in the cup cleaning area; The transfer station processes the reaction cups gripped by the grippers.

[0017] Compared with the prior art, the technical effects of the present invention are: The present invention arranges a cup measuring area and a cup cleaning area above the incubation tray, and arranges a detection mechanism on one side of the cup position in the cup measuring area. The detection mechanism is used to detect whether a reaction cup exists in the cup measuring area. If so, the incubation tray carries the reaction cup in the cup measuring area and rotates to the cup cleaning area, and the reaction cup is cleaned away from the cup cleaning area, thereby effectively improving the cup cleaning efficiency when the incubation chamber is shut down and restarted. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a top view of the incubation tray; Figure 2 It is an enlarged schematic diagram of part A on the incubation plate; Figure 3 It is an enlarged schematic diagram of part B on the incubation plate; Figure 4 is a schematic diagram of a detection unit; Figure 5 It is a schematic diagram of the arrangement of the detection reaction cups of the six detection units; Figure 6 It is a schematic diagram of the structure of the incubation chamber; Figure 7 is a schematic diagram of the incubation cover; Figure 8 is a cross-sectional view of an incubation device; Fig. 9 It is the overall structural diagram of the incubation device.

[0019] Figure numerals: 1-turntable, 2-detection mechanism, 201-detection unit, 202-mounting bracket, 203-optical coupling plate, 204-optical coupling, 3-cup measuring area, 4-cup cleaning area, 5-cup position, 6-reaction cup, 7-shell, 8-incubation cover, 9-cup cleaning position hole, 10-base assembly, 11-heating assembly, 12-driving assembly. Implementation

[0020] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention. Example 1

[0021] like Figure 1 As shown, an incubation tray comprises a turntable 1, and a cup measuring area 3 and a cup cleaning area 4 are provided above the turntable 1.

[0022] like Figure 2 As shown, a plurality of cup positions 5 are arranged on the incubation plate, and the cup positions 5 are used to accommodate reaction cups 6. Specifically, the cup positions 5 are arranged on the turntable 1, and more than two circles of cup positions 5 are arranged circumferentially on the turntable 1. In this embodiment, six circles of cup positions 5 are arranged circumferentially on the turntable 1.

[0023] like Figure 2 , 3 As shown, the cup positions 5 in the cup measuring area 3 and the cup cleaning area 4 can be arranged into one group, two groups or multiple groups, each group of cup positions 5 is composed of single cup positions 5 adjacent to each other in each circle, and each group of cup positions 5 has a total of six cup positions 5.

[0024] like Figure 2As shown, a detection mechanism 2 is provided on one side of the cup position 5 rotated to the measuring cup area 3, for detecting whether there is a reaction cup 6 on the cup position 5 rotated to the measuring cup area 3 when the incubation disk is shut down and restarted. If there is, the incubation disk rotates the reaction cup 6 at the measuring cup area 3 to the cup cleaning area 4 for taking out the reaction cup 6.

[0025] like Figure 2 , 4 As shown, the detection mechanism 2 includes a plurality of detection units 201, and the detection units 201 correspond to the cup positions 5 rotated into the measuring cup area 3. The detection unit 201 includes a mounting bracket 202, an optical coupling plate 203 and an optical coupler 204, wherein the optical coupling plate 203 is mounted on the mounting bracket 202, and the optical coupler 204 is connected to the optical coupling plate 203. In this embodiment, the optical coupling plate 203 is a PCB board, and the optical coupler 204 is specifically a reflective optical coupler, which can achieve the purpose of simple structure, economical and convenient disassembly. Furthermore, the distance between the reflective optical coupler and the outer side of the cup edge of the reaction cup 6 carried on the cup position 5 is set to 2-3mm, which is the detection distance of the reflective optical coupler, which can avoid false detection caused by excessive detection distance.

[0026] In other embodiments, the reflective photoelectric sensor in this embodiment may be replaced with the following types of optical couplers: a through-beam photoelectric sensor, a slot photoelectric sensor, or a reflector photoelectric sensor, all of which can achieve the purpose of the present invention.

[0027] In this embodiment, there are six detection units 201 , which correspond one to one with the cup positions 5 rotated into the measuring cup area 3 . The detection units 201 are installed by means of a mounting bracket 202 .

[0028] like Figure 5 As shown, in this embodiment, the six reflective optical couplers in the detection unit 201 are staggered, and correspondingly, the adjacent cup positions 5 between each circle are also staggered. When the incubation plate cooperates with other mechanisms such as a clamping mechanism, when the cup position 5 originally in the measuring cup area 3 rotates to the cup cleaning area 4, the clamping mechanism has enough clamping space when clamping the reaction cup 6. The staggered distribution of the reflective optical couplers can significantly improve the utilization efficiency of the space.

[0029] In the present technical solution, when the incubation tray is shut down and restarted, the reflective optical coupler detects in sequence whether there is a reaction cup 6 on the cup position 5 rotated to the measuring cup area 3 in a full circle. If there is, the corresponding position is recorded. When the cup position 5 with the reaction cup 6 rotates to the cup cleaning area 4, the reaction cups 6 are taken out in sequence to complete all cleaning work of the reaction cups 6 on the incubation tray, which can effectively improve the cup cleaning efficiency when the incubation tray is shut down and restarted. Example 2

[0030] like Figure 6As shown, the present invention also provides an incubation chamber, including a shell 7 with an open structure at the upper end and an incubation tray as described in Example 1 arranged in the shell 7, and an incubation cover 8 is arranged above the shell 7 to cooperate with the shell 7 to keep the incubation tray warm.

[0031] like Figure 7 As shown, the incubation cover 8 is further provided with cup cleaning holes 9 corresponding to the cup cleaning area 4. The cup cleaning holes 9 can be arranged into one group, two groups or multiple groups according to the cup cleaning area 4, and the cup cleaning holes 9 corresponding to each group of cup positions 5 in the cup cleaning area 4 are a group of cup cleaning holes 9, so that the reaction cups 6 in the cup cleaning area 4 can be directly taken out from the cup cleaning holes 9.

[0032] In this embodiment, Figure 7 As shown, the cup cleaning holes 9 are arranged in a group, that is, there are six cup cleaning holes 9, and the cup cleaning holes 9 are staggered on the incubation cover 8. The cup cleaning holes 9 are through holes, and each cup cleaning hole 9 is large enough for a clamp in an open state to pass through.

[0033] In this embodiment, Figure 7 As shown, six detection units 201 in a group of detection units 201. Figure 4 As shown, the detection units 201 are all installed through the mounting bracket 202, and the reflective optical couplers are all installed on the incubation cover 8 through the mounting bracket 202. In other technical solutions, according to actual needs, some detection units 201 in a group of detection units can be installed on the incubation cover 8, and the remaining detection units 201 can be installed on the shell 7 of the incubation chamber, and it is only necessary to meet the detection unit 201 can perform normal detection in the measuring cup area 3.

[0034] In the present technical scheme, when the incubation chamber is shut down and restarted, the reflective optical coupler on the incubation chamber detects in sequence whether there is a reaction cup 6 in the cup position 5 rotated to the measuring cup area 3 in a full circle. If there is, the corresponding position is recorded, and when the cup position 5 with the reaction cup 6 rotates to the cup cleaning area 4, the reaction cups 6 are taken out in sequence, completing all the cleaning work of the reaction cups 6 on the incubation tray, which can effectively improve the cup cleaning efficiency when the incubation tray is shut down and restarted. Example 3

[0035] like Figure 8 , Fig. 9 As shown, an incubation device includes the incubation chamber in Example 2, and also includes a base component 10, a heating component 11 and a driving component 12; the heating component 11 is installed at the bottom of the incubation tray, and is used to heat and incubate the reaction cup 6 on the cup position 5 on the incubation tray; the driving component 12 is connected to the incubation tray, and is used to drive the incubation tray to rotate.

[0036] like Fig. 9As shown, the base assembly 10 includes at least one pillar, which is connected to the bottom of the incubation chamber housing 7 to support the incubation chamber. In this embodiment, three pillars are evenly distributed along the circumference below the housing 7 to further improve the stability of the incubation chamber.

[0037] The driving assembly 12 is used to provide power for the rotation of the incubation tray. The driving assembly 12 includes a motor, a synchronous wheel mechanism connected to the motor output shaft, and a central shaft connected to the synchronous wheel mechanism and the incubation tray respectively. The motor provides power for the synchronous wheel mechanism to drive the central shaft to rotate, and the rotation of the central shaft drives the incubation tray to rotate.

[0038] In this embodiment, the driving assembly 12 drives the incubation tray to rotate clockwise, and the cup cleaning method in this technology is consistent with the cup cleaning method in Example 2. Example 4

[0039] A sample analyzer includes the incubation device in Example 3, and also includes a clamp for clamping the reaction cup 6 in the cup cleaning area 4; and a transfer station for processing the reaction cup 6 clamped by the clamp.

[0040] The cup cleaning scheme in the present technical scheme is as follows: when the incubation device is shut down and restarted, the cups need to be cleaned in the incubation chamber, and the reflective optical coupler detects whether there is a reaction cup 6 on the cup position 5 rotated to the measuring cup area 3 in a full circle. If there is, the corresponding position is recorded, and when the cup position 5 with the reaction cup 6 rotates to the cup cleaning area 4, the reaction cups 6 are taken out in turn to complete all the cleaning work of the reaction cups 6 on the incubation tray, which can effectively improve the cup cleaning efficiency when the incubation tray is shut down and restarted.

[0041] In summary, the present invention arranges a cup measuring area and a cup cleaning area above the incubation tray, and arranges a reflective photocoupler detection mechanism on one side of the cup position in the cup measuring area. The reflective photocoupler then detects whether there is a reaction cup at the cup position rotated into the cup measuring area. If so, the incubation tray carries the reaction cup in the cup measuring area and rotates to the cup cleaning area. The reaction cups are cleaned away from the cup cleaning area in turn until all the reaction cups on the incubation tray are cleaned, thereby effectively improving the cup cleaning efficiency when the incubation chamber is shut down and restarted.

[0042] The above-mentioned embodiments only express several implementation methods of the present invention, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the patent. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present invention, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the patent of the present invention shall be subject to the attached claims.

Claims

1. An incubation tray, characterized in that: include: A turntable (1) is provided with a cup measuring area (3) and a cup cleaning area (4); A plurality of cup positions (5) are arranged on the incubation tray and are used to accommodate reaction cups (6); The detection mechanism (2) is arranged on one side of the cup position (5) rotated to the measuring cup area (3), and is used to detect whether the reaction cup (6) exists in the cup position (5) rotated to the measuring cup area (3) when the incubation tray is stopped and restarted. If yes, the incubation tray rotates the reaction cup (6) in the measuring cup area (3) to the cup cleaning area (4) so ​​that the reaction cup (6) can be taken out.

2. The incubation tray according to claim 1, characterized in that The detection mechanism (2) comprises a plurality of detection units (201), and the detection units (201) correspond one-to-one to the cup positions (5) rotated into the measuring cup area (3).

3. The incubation tray according to claim 2, characterized in that The detection unit (201) comprises: Mounting bracket (202); An optical coupling plate (203) mounted on the mounting bracket (202); An optical coupler (204) is connected to the optical coupling board (203).

4. The incubation tray according to claim 3, characterized in that: The optical coupler (204) is a reflective optical coupler.

5. The incubation tray according to claim 3, characterized in that: The distance between the optical coupler (204) and the outer side of the cup edge of the reaction cup (6) on the corresponding cup position (5) is 2-3 mm.

6. The incubation tray according to claim 1, characterized in that: The rotating disk (1) is provided with more than two circles of cup positions (5) along the circumferential direction.

7. The incubation tray according to claim 6, characterized in that: The adjacent cup positions (5) between each circle layer are staggeredly distributed.

8. An incubation chamber, characterized in that: include: A housing (7) with an open structure at the upper end; An incubation tray as claimed in any one of claims 1 to 7 arranged in a housing (7).

9. The incubation chamber according to claim 8, characterized in that: The incubation chamber further comprises an incubation cover (8) which is arranged above the shell (7).

10. The incubation chamber according to claim 9, characterized in that: The incubation cover (8) is provided with a cup cleaning hole (9) corresponding to the cup cleaning area (4) for taking out the reaction cup (6).

11. An incubation device, characterized in that: include: The incubation chamber according to any one of claims 8 to 10; A base assembly (10) for supporting the incubation chamber; A heating component (11), installed at the bottom of the incubation tray, used for heating and incubating the reaction cup (6) at the cup position (5) on the incubation tray; A driving assembly (12) is connected to the incubation tray and is used to drive the incubation tray to rotate.

12. A sample analyzer, characterized in that: include: The incubation tray according to any one of claims 1 to 7, the incubation chamber according to any one of claims 8 to 10, or the incubation device according to claim 11; A clamping claw, used for clamping a reaction cup (6) in the cup cleaning area (4); The transfer station processes the reaction cup (6) gripped by the gripper.