Near-infrared absorption supramolecular cationic free radical as well as preparation method and application thereof
By designing supramolecular cationic radicals with macrocyclic molecules, using supramolecular self-assembly technology and oxidation process, the problem that the cationic radical absorption spectrum in the existing technology has not reached the near-infrared region, and a stronger near-infrared absorption and photo-thermal conversion capability is achieved, which is suitable for photothermal therapy.
CN119707991APending Publication Date: 2025-03-28NINGBO INST OF MATERIALS TECH & ENG CHINESE ACAD OF SCI
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Patent Information
- Application Number
- CN202411886617.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-19
- Publication Date
- 2025-03-28
AI Technical Summary
Technical Problem
In the prior art, the absorption spectrum of cationic radicals does not reach the near-infrared region, limiting its application in photothermal therapy.
Method used
By designing a supramolecular cationic radical with macrocyclic molecules, using supramolecular self-assembly technology to form a complex with guest molecules, and losing an electron through oxidation, a supramolecular cationic radical with near-infrared absorption capacity is obtained.
Benefits of technology
It has achieved absorption in the near-infrared region, with better water solubility, longer free radical life, stronger near-infrared absorption capacity, better photothermal conversion capacity and stronger photothermal killing pathogens and tumor cells.
✦ Generated by Eureka AI based on patent content.
Abstract
The invention discloses a near-infrared absorption supramolecular cation free radical as well as a preparation method and application thereof, and belongs to the technical field of photo-thermal therapy. The supramolecular cation free radical is obtained by taking a supramolecular host compound as a stabilizer, forming a compound by supramolecular self-assembly of the supramolecular host compound and a guest molecule compound in an aqueous solution, and then oxidizing to lose an electron. Compared with an original-guest cation free radical (the structural formula is shown in the formula II), the supramolecular cation free radical has better water solubility, longer free radical life, stronger near-infrared absorption capability, more excellent photothermal conversion capability and stronger capability of photothermally killing pathogenic bacteria and tumor cells.
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