Analysis device for drug detection

Abstract

The invention discloses an analysis device for drug detection, which comprises a base and a fixed plate arranged on the top surface of the base, a rotating plate is rotatably arranged on the surface of the fixed plate, a plurality of liquid storage cylinders are arranged in the rotating plate, and burettes are arranged on the bottom surface of the rotating plate and located at the bottom ends of the liquid storage cylinders. And an adjusting frame is fixedly arranged on the bottom surface of the fixing plate through a supporting rod. According to the analysis device for drug detection, through the arrangement of the cleaning and drying mechanism, the interior of the burette can be automatically flushed under the condition that the burette does not need to be disassembled, it is ensured that residual titration liquid and impurities are thoroughly removed, interference to next titration is avoided, and after cleaning is completed, the titration liquid can be completely separated from the burette. According to the burette drying device, residual liquid in a burette can be quickly discharged and dried in time, so that the burette is ensured to be in a dry and clean state, good conditions are created for subsequent titration analysis work, and meanwhile, the labor force is also reduced.

Description

Technical Field

[0001] The present invention relates to the technical field of drug detection, in particular to an analysis device for drug detection. Background Art

[0002] Titration analysis is one of the methods for drug analysis and testing. It is widely used in the pharmaceutical industry. It can be used for the analysis and content determination of drugs and their raw materials. It is suitable for quality control and routine analysis in the drug production process.

[0003] According to the patent application number CN202023146812.7, an analysis device, a fixing device and a titration device are provided. A fixing device is provided on the upper surface of the analysis device, and a titration device is welded on one surface of the analysis device. First, open the fixing clamp, place the analysis bottle in the middle of the fixing clamp, and tightly fix the analysis bottle through the screw fit of the bolt and the nut. Then place the burette in the fixing ring, rotate the handle, and fix it through the screw fit of the fixing ring and the limit column. Press the button, and the button controls the battery to start. The battery supplies power to the pressure sensor, the information processing chip and the display screen. The burette drips the medicine into the analysis bottle, and the pressure sensor transmits the measured information to the information processing chip. The information is transmitted to the display screen after passing through the information processing chip, so as to achieve fast and accurate analysis of the drug and prevent shaking.

[0004] In the above patent, after the titration analysis is completed, the inside of the burette is not automatically cleaned and emptied, resulting in the residual standard solution not being completely removed, which is likely to interfere with the subsequent titration analysis of the drug and affect the analysis results. In addition, the above patent can only titrate one standard solution. When different standard solutions need to be dripped into the analysis bottle, personnel usually need to manually replace them, which is likely to delay the mixing efficiency between the standard solution and the drug and increase the labor intensity. Therefore, in view of the above shortcomings, the present invention makes the following improvements: Summary of the invention

[0005] In view of the shortcomings of the prior art, the present invention provides an analytical device for drug detection, which solves the problems mentioned in the background technology.

[0006] To achieve the above objectives, the present invention is implemented through the following technical solutions: an analytical device for drug detection, comprising a base and a fixed plate arranged on the top surface of the base, a rotating plate is rotatably arranged on the surface of the fixed plate, and a plurality of liquid storage cylinders are arranged inside the rotating plate, a burette is arranged on the bottom surface of the rotating plate and at the bottom end of the liquid storage cylinder, an adjustment frame is fixedly arranged on the bottom surface of the fixed plate through a support rod, and a cleaning and drying mechanism is arranged on the surface of the adjustment frame, the inside of the burette is cleaned and dried by the cleaning and drying mechanism to remove the standard solution remaining inside the burette, the cleaning and drying mechanism comprises a cleaning part and a drying part, and the cleaning part and the drying part are connected by a double-rod hydraulic cylinder, and a driving part for controlling the double-rod hydraulic cylinder to move horizontally is arranged on the bottom surface of the fixed plate;

[0007] The cleaning part includes a water outlet pipe arranged on the bottom surface of the fixing plate, and the bottom end of the water outlet pipe is connected to a water delivery pipe through the mounting plate;

[0008] The drying element comprises a water receiving box arranged at the bottom end of the water delivery pipe, and an air blowing nozzle is arranged inside the water receiving box.

[0009] Preferably, a water tank is fixedly provided on the top surface of the fixed plate via a support column, the top end of the water outlet pipe passes through the fixed plate and is connected to the bottom surface of the water tank, a drainage cylinder is fixedly provided on the top surface of the base, and the bottom surface of the water receiving box is connected to the surface of the drainage cylinder via an L-shaped tube.

[0010] Preferably, a protective plate is slidably provided on the surface of the water pipe, and the top surface of the protective plate is connected to the bottom surface of the mounting plate through a first telescopic tube, a pressure switch is fixedly provided on one side of the bottom surface of the mounting plate, and a contact block is fixedly provided on one side of the top surface of the protective plate.

[0011] Preferably, the drying element also includes a hair dryer fixedly arranged on the bottom surface of the base, and the air outlet of the hair dryer is connected to an air outlet pipe, one end of the air outlet pipe passes through the drainage cylinder and extends to the top of the drainage cylinder, and the surface of the air outlet pipe is connected to the bottom end of the blowing nozzle through the exhaust pipe.

[0012] Preferably, the surfaces of the water outlet pipe, the L-shaped pipe and the air outlet pipe are all provided with telescopic sections.

[0013] Preferably, the driving member includes a screw rod rotatably arranged on the top surface of the adjusting frame, and a sliding ring is threadedly connected to the surface of the screw rod, an inclined rod is rotatably arranged on the surface of the sliding ring, a sliding rod is slidably arranged inside the adjusting frame, and one end of the sliding rod passes through the adjusting frame and is fixedly connected to the surface of the double-rod hydraulic cylinder, the bottom end of the inclined rod is rotatably connected to the top surface of the sliding rod, and the two protruding ends of the double-rod hydraulic cylinder are respectively fixedly connected to a water receiving box and one side of a mounting plate.

[0014] Preferably, an electric push rod is fixedly provided inside the rotating plate, and a U-shaped rod is fixedly provided at the protruding end of the electric push rod, and an adjusting piece is provided on the surface of the U-shaped rod, and the adjusting piece is used to adjust the swing angle of the burette.

[0015] Preferably, the adjusting member comprises a rotating rod rotatably arranged between two sides of the inner wall of the U-shaped rod, and a limiting ring is rotatably arranged on one side of the surface of the rotating rod through the Y-shaped rod, and a fastening bolt is threadedly connected to the surface of the limiting ring.

[0016] Preferably, a transmission gear is fixedly connected to the surface of the rotating rod, a spring rod is fixedly provided on the top surface of the inner wall of the U-shaped rod, and a semicircular plate is fixedly provided on the bottom end of the spring rod, and teeth meshing with the transmission gear are fixedly provided on the surface of the semicircular plate.

[0017] Preferably, the bottom end of the liquid storage cylinder is connected to a second telescopic tube adapted to the burette.

[0018] Beneficial Effects

[0019] The present invention provides an analytical device for drug detection, which has the following beneficial effects compared with the prior art:

[0020] (1) The drug detection analysis device, through the provision of a cleaning and drying mechanism, can automatically rinse the inside of the burette without disassembling the burette, ensuring that the residual titrant and impurities are completely removed to avoid interference with the next titration. After the cleaning is completed, the residual liquid in the burette can be quickly discharged and dried in time to ensure that the burette is in a dry and clean state, creating good conditions for subsequent titration analysis work and also reducing labor.

[0021] (2) The drug detection analysis device can realize titration analysis of multiple standard solutions through the coordinated arrangement of multiple liquid storage cylinders and burettes, without the need for manual switching by personnel. The automated operation can improve the mixing efficiency between the subsequent standard solutions and the drugs.

[0022] (3) The drug detection analysis device can adjust the inclination angle of the burette during the titration process by setting the adjustment part, so that the standard solution in the liquid storage cylinder can flow out along the inner wall of the analysis bottle, which can avoid the solution splashing caused by the vertical titration method used in the prior art, and lay a foundation for the accuracy of the subsequent drug titration analysis results. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 A three-dimensional diagram of the structure of the present invention;

[0024] Figure 2 It is a structural schematic diagram of the driving member of the present invention;

[0025] Figure 3 It is a side view of the second motor and driving gear structure of the present invention;

[0026] Figure 4 It is a schematic diagram of the structure of the cleaning element of the present invention;

[0027] Figure 5 For the present invention Figure 1 A partial enlarged view of the middle A;

[0028] Figure 6 For the present invention Figure 1 A partial enlarged view of point B in the middle.

[0029] In the figure: 1. fixed plate; 2. rotating plate; 3. liquid storage cylinder; 4. burette; 5. adjusting frame; 6. cleaning part; 61. water outlet pipe; 62. mounting plate; 63. water delivery pipe; 64. water storage tank; 65. drainage cylinder; 66. L-shaped pipe; 67. first telescopic pipe; 68. pressure switch; 69. contact block; 7. drying part; 71. hair dryer; 72. air outlet pipe; 73. exhaust pipe; 74. blowing nozzle; 75. water receiving box; 8. double-rod hydraulic cylinder; 9. adjusting part; 91. rotating rod; 92. limit ring; 93. transmission gear; 94. spring rod; 95. semicircular plate; 10. screw rod; 11. sliding ring; 12. inclined rod; 13. sliding rod; 14. electric push rod; 15. U-shaped rod; 16. second telescopic pipe; 17. first motor; 18. second motor; 19. driving gear. DETAILED DESCRIPTION

[0030] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0031] Embodiment 1

[0032] See also Figures 1 to 5 As shown, the present invention provides a technical solution, and the specific improvements are as follows:

[0033] A drug detection analysis device comprises a base and a fixed plate 1 arranged on the top surface of the base, a rotating plate 2 is rotatably arranged on the surface of the fixed plate 1, and a plurality of liquid storage cylinders 3 are arranged inside the rotating plate 2, the bottom end of the liquid storage cylinder 3 is connected with a second telescopic tube 16 adapted to a burette 4, the second telescopic tube 16 can be inserted from the top end of the burette 4, and a first non-return valve is arranged inside the second telescopic tube 16, a burette 4 is arranged on the bottom surface of the rotating plate 2 and at the bottom end of the liquid storage cylinder 3, an adjustment frame 5 is fixedly arranged on the bottom surface of the fixed plate 1 through a support rod, and a cleaning and drying mechanism is arranged on the surface of the adjustment frame 5, the inside of the burette 4 is cleaned and dried by the cleaning and drying mechanism, and is used to remove the standard solution remaining inside the burette 4, the cleaning and drying mechanism comprises a cleaning part 6 and a drying part 7, and the cleaning part 6 and the drying part 7 are connected by a double-rod hydraulic cylinder 8, and a driving part for controlling the double-rod hydraulic cylinder 8 to move horizontally is arranged on the bottom surface of the fixed plate 1;

[0034] The driving member includes a screw rod 10 rotatably arranged on the top surface of the adjusting frame 5, and a sliding ring 11 is threadedly connected to the surface of the screw rod 10, a first motor 17 is fixedly arranged on the bottom surface of the fixed plate 1, and the output end of the first motor 17 is fixedly connected to the top end of the screw rod 10 through a coupling, an inclined rod 12 is rotatably arranged on the surface of the sliding ring 11, a sliding rod 13 is slidably arranged inside the adjusting frame 5, and one end of the sliding rod 13 penetrates the adjusting frame 5 and is fixedly connected to the surface of the double-rod hydraulic cylinder 8, the bottom end of the inclined rod 12 is rotatably connected to the top surface of the sliding rod 13, and the two protruding ends of the double-rod hydraulic cylinder 8 are respectively fixedly connected to the water receiving box 75 and one side of the mounting plate 62;

[0035] The cleaning part 6 includes a water outlet pipe 61 arranged on the bottom surface of the fixed plate 1, and the bottom end of the water outlet pipe 61 is connected to a water pipe 63 through a mounting plate 62. A water tank 64 is fixedly arranged on the top surface of the fixed plate 1 through a supporting column. A second motor 18 is fixedly arranged on the back of the water tank 64, and a driving gear 19 is fixedly arranged on the output end of the second motor 18 through a coupling. Teeth meshing with the driving gear 19 are fixedly arranged on the surface of the rotating plate 2. Both sides of the water tank 64 are fixedly connected to the top surface of the base through supporting columns. The top end of the water outlet pipe 61 passes through the fixed plate 1 and is connected to the bottom surface of the water tank 64. A drainage cylinder 65 is fixedly arranged on the top surface of the base. The front of the water cylinder 65 is connected with a drain pipe, the bottom surface of the water receiving box 75 is connected with the surface of the drain cylinder 65 through an L-shaped tube 66, a protective plate is slidably provided on the surface of the water delivery pipe 63, and the top surface of the protective plate is connected with the bottom surface of the mounting plate 62 through a first telescopic tube 67, a pressure switch 68 is fixedly provided on one side of the bottom surface of the mounting plate 62, a contact block 69 is fixedly provided on one side of the top surface of the protective plate, a second one-way valve is provided inside the water outlet pipe 61, and the pressure switch 68 on the mounting plate 62 can control the opening of the corresponding second one-way valve inside the upper water outlet pipe 61, and a buffer spring is provided between the protective plate and the opposite side of the mounting plate 62 and on the surface of the water delivery pipe 63;

[0036] The drying member 7 includes a water receiving box 75 arranged at the bottom end of the water delivery pipe 63, and a blowing nozzle 74 is arranged inside the water receiving box 75, and a filter frame is movably arranged inside the water receiving box 75, and impurities in the waste water can be filtered out by the filter frame. The drying member 7 also includes a hair dryer 71 fixedly arranged on the bottom surface of the base, and the air outlet of the hair dryer 71 is connected to the air outlet pipe 72, and a check valve is arranged inside the water outlet pipe 61. The surfaces of the water outlet pipe 61, the L-shaped pipe 66 and the air outlet pipe 72 are all provided with telescopic sections, so that the water outlet pipe 61, the L-shaped pipe 66 and the air outlet pipe 72 can be telescopic. One end of the air outlet pipe 72 passes through the drain cylinder 65 and extends to the top of the drain cylinder 65, and the surface of the air outlet pipe 72 is connected to the bottom end of the blowing nozzle 74 through the exhaust pipe 73;

[0037] When it is necessary to clean the inside of the burette 4, the analysis bottle is removed, the burette 4 is controlled to move downward and separate from the liquid storage cylinder 3, and then the first motor 17 is started, so that the first motor 17 drives the screw rod 10 to rotate, and the sliding ring 11 on the surface of the screw rod 10 moves downward. During the movement, the sliding rod 13 can be pushed to move outward along the adjustment frame 5 through the rotation setting of the inclined rod 12, so that the double-rod hydraulic cylinder 8 can be pushed until the mounting plate 62 and the water receiving box 75 on the double-rod hydraulic cylinder 8 are pushed to the top and bottom ends of the burette 4 respectively. With the setting of the double-rod hydraulic cylinder 8, it can The protective plate is in contact with the top of the burette 4, and the mounting plate 62 is controlled to be continuously pressed down. When the contact block 69 on the protective plate contacts the pressure switch 68, the second one-way valve inside the upper water outlet pipe 61 can be controlled by the pressure switch 68 to open. At this time, the cleaning water inside the water storage tank 64 enters the interior of the burette 4 through the water outlet pipe 61 and the water delivery pipe 63, so that the interior of the burette 4 can be flushed. Similarly, by controlling the mounting plate 62 to rise, the protective plate is moved away from the burette 4, and the contact block 69 can be moved away from the pressure switch 68 under the action of the buffer spring, so that the second one-way valve is closed and the water outlet is stopped.

[0038] At the same time, the water collecting box 75 is located at the bottom end of the burette 4, which can collect waste water generated during cleaning. Finally, the waste water enters the drain tube 65 through the L-shaped tube 66 to be combined and discharged from the drain pipe. After the waste water is drained, the check valve and the hair dryer 71 are opened. The hair dryer 71 can blow air into the burette 4 through the air outlet pipe 72, so that the inside of the burette 4 can be dried.

[0039] Embodiment 2

[0040] Based on Example 1, please refer to Figure 1 and Figure 6 The specific improvements are as follows:

[0041] An electric push rod 14 is fixedly arranged inside the rotating plate 2, and a U-shaped rod 15 is fixedly arranged at the protruding end of the electric push rod 14, and an adjusting member 9 is arranged on the surface of the U-shaped rod 15, and the adjusting member 9 is used to adjust the swing angle of the burette 4, and the adjusting member 9 includes a rotating rod 91 rotatably arranged between the two sides of the inner wall of the U-shaped rod 15, and a limiting ring 92 is rotatably arranged on one side of the surface of the rotating rod 91 through a Y-shaped rod, and a fastening bolt is threadedly connected to the surface of the limiting ring 92;

[0042] The burette 4 is clamped inside the limiting ring 92 and fixed by tightening bolts. During the titration of a single standard solution, the analysis bottle is placed directly below the liquid storage cylinder 3 storing the standard solution. At this time, the burette 4 is located at the top of the analysis bottle. The electric push rod 14 is started, so that the extended end of the electric push rod 14 drives the burette 4 to rise through the U-shaped rod 15, the Y-shaped rod and the limiting ring 92 until the second telescopic tube 16 is inserted into the burette 4. During the subsequent titration, the swing angle of the burette 4 can be adjusted so that the subsequent standard solution can flow out along the inner wall of the analysis bottle to avoid the splashing of the standard solution during the titration.

[0043] Embodiment 3

[0044] Based on Example 2, please refer to Figure 1 and Figure 6 The specific improvements are as follows:

[0045] A transmission gear 93 is fixedly connected to the surface of the rotating rod 91, a spring rod 94 is fixedly arranged on the top surface of the inner wall of the U-shaped rod 15, and a semicircular plate 95 is fixedly arranged at the bottom end of the spring rod 94, and teeth meshing with the transmission gear 93 are fixedly arranged on the surface of the semicircular plate 95;

[0046] During adjustment, the semicircular plate 95 is manually controlled to rise, so that the teeth on the bottom surface of the semicircular plate 95 are separated from the transmission gear 93, and then the rotating rod 91 is rotated. At this time, the Y-shaped rod and the limit ring 92 synchronously drive the burette 4 to adjust the angle. After adjusting the appropriate tilt angle, the semicircular plate 95 is loosened, so that the semicircular plate 95 is meshed with the surface of the transmission gear 93 through the teeth under the action of the spring rod 94, thereby achieving the fixation of the rotating rod 91 after the angle adjustment, avoiding the phenomenon of the position of the burette 4 being offset after adjustment. In the process of adjusting the tilt angle of the burette 4, the second telescopic tube 16 can bend to a certain extent inside the burette 4 adaptively, without affecting the outflow of the standard solution inside the liquid storage cylinder 3;

[0047] When different standard solutions need to be dripped into the analysis bottle, the second motor 18 is started, so that the second motor 18 drives the rotating plate 2 to rotate through the cooperation of the driving gear 19 and the teeth. At this time, the liquid storage cylinder 3 arranged inside the rotating plate 2 rotates synchronously, wherein four liquid storage cylinders 3 are arranged, each storing a different standard solution. By controlling the liquid storage cylinder 3 of the corresponding standard solution to rotate to be located above the analysis bottle, the titration analysis operation of different standard solutions can be realized.

[0048] Meanwhile, the contents not described in detail in this specification belong to the prior art known to those skilled in the art.

[0049] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An analytical device for drug detection, comprising a base and a fixing plate (1) arranged on the top surface of the base, characterized in that: The surface of the fixed plate (1) is rotatably provided with a rotating plate (2), and a plurality of liquid storage cylinders (3) are arranged inside the rotating plate (2); a burette (4) is arranged on the bottom surface of the rotating plate (2) and at the bottom end of the liquid storage cylinder (3); an adjustment frame (5) is fixedly arranged on the bottom surface of the fixed plate (1) via a support rod, and a cleaning and drying mechanism is arranged on the surface of the adjustment frame (5); the inside of the burette (4) is cleaned and dried by the cleaning and drying mechanism to remove the standard solution remaining inside the burette (4); the cleaning and drying mechanism comprises a cleaning part (6) and a drying part (7), and the cleaning part (6) and the drying part (7) are connected by a double-rod hydraulic cylinder (8); and a driving part for controlling the double-rod hydraulic cylinder (8) to move horizontally is arranged on the bottom surface of the fixed plate (1); The cleaning component (6) comprises a water outlet pipe (61) arranged on the bottom surface of the fixing plate (1), and the bottom end of the water outlet pipe (61) is connected to a water delivery pipe (63) through a mounting plate (62); The drying element (7) comprises a water receiving box (75) arranged at the bottom end of the water delivery pipe (63), and an air blowing nozzle (74) is arranged inside the water receiving box (75).

2. The drug detection analysis device according to claim 1, characterized in that: A water storage tank (64) is fixedly arranged on the top surface of the fixing plate (1) via a support column; the top end of the water outlet pipe (61) passes through the fixing plate (1) and is connected to the bottom surface of the water storage tank (64); a drainage cylinder (65) is fixedly arranged on the top surface of the base; and the bottom surface of the water receiving box (75) is connected to the surface of the drainage cylinder (65) via an L-shaped tube (66).

3. A drug detection analysis device according to claim 2, characterized in that: A protective plate is slidably provided on the surface of the water delivery pipe (63), and the top surface of the protective plate is connected to the bottom surface of the mounting plate (62) via a first telescopic tube (67). A pressure switch (68) is fixedly provided on one side of the bottom surface of the mounting plate (62), and a contact block (69) is fixedly provided on one side of the top surface of the protective plate.

4. The drug detection analysis device according to claim 3, characterized in that: The drying member (7) further comprises a hair dryer (71) fixedly arranged on the bottom surface of the base, and an air outlet of the hair dryer (71) is connected to an air outlet pipe (72), one end of the air outlet pipe (72) penetrates the drainage cylinder (65) and extends to the top end of the drainage cylinder (65), and the surface of the air outlet pipe (72) is connected to the bottom end of the blowing nozzle (74) through an exhaust pipe (73).

5. The drug detection analysis device according to claim 4, characterized in that: The surfaces of the water outlet pipe (61), the L-shaped pipe (66) and the air outlet pipe (72) are all provided with telescopic sections.

6. The drug detection analysis device according to claim 1, characterized in that: The driving member comprises a screw rod (10) rotatably arranged on the top surface of the adjusting frame (5), and the surface of the screw rod (10) is threadedly connected with a sliding ring (11), and the surface of the sliding ring (11) is rotatably arranged with an inclined rod (12), and the interior of the adjusting frame (5) is slidably arranged with a sliding rod (13), and one end of the sliding rod (13) penetrates the adjusting frame (5) and is fixedly connected to the surface of the double-rod hydraulic cylinder (8), the bottom end of the inclined rod (12) is rotatably connected to the top surface of the sliding rod (13), and the two protruding ends of the double-rod hydraulic cylinder (8) are respectively fixedly connected to the water receiving box (75) and one side of the mounting plate (62).

7. The drug detection analysis device according to claim 1, characterized in that: An electric push rod (14) is fixedly arranged inside the rotating plate (2), and a U-shaped rod (15) is fixedly arranged at the protruding end of the electric push rod (14). An adjusting member (9) is arranged on the surface of the U-shaped rod (15), and the adjusting member (9) is used to adjust the swing angle of the burette (4).

8. The drug detection analysis device according to claim 7, characterized in that: The adjusting member (9) comprises a rotating rod (91) rotatably arranged between two sides of the inner wall of the U-shaped rod (15), and a limiting ring (92) is rotatably arranged on one side of the surface of the rotating rod (91) through a Y-shaped rod, and a fastening bolt is threadedly connected to the surface of the limiting ring (92).

9. The drug detection analysis device according to claim 8, characterized in that: A transmission gear (93) is fixedly connected to the surface of the rotating rod (91), a spring rod (94) is fixedly arranged on the top surface of the inner wall of the U-shaped rod (15), and a semicircular plate (95) is fixedly arranged at the bottom end of the spring rod (94), and teeth meshing with the transmission gear (93) are fixedly arranged on the surface of the semicircular plate (95).

10. The drug detection analysis device according to claim 1, characterized in that: The bottom end of the liquid storage cylinder (3) is connected to a second telescopic tube (16) adapted to the burette (4).

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