Plant long-acting bactericide

Abstract

The invention provides a long-acting bactericide for plants. The long-acting bactericide comprises the following components in percentage by weight: 0.5-3% of a radix stemonae diphyllae extracting solution; 0.5-3% of a calendula extracting solution; 0.5-3% of a myrrh extracting solution; 0.5-3% of a cortex phellodendri extracting solution; 0.05 to 0.5 percent of a cationic surface active agent; 87.5% to 97.95% of water; according to the plant long-acting bactericide provided by the invention, alkaloid contained in the radix stemonae, berberine and magnoflorine in the cortex phellodendri, polysaccharide amino acid in the radix stemonae and gallic acid in the myrrh can form a stable acid-base association body, and the acid-base association body jointly acts on bacteria and viruses, so that the killing effect on the bacteria and the viruses is realized; the cationic surface active agent has remarkable dispersing and compatibilizing effects on flavone and resin in the natural plant extract, a stable clear solution can be formed, and meanwhile, R4-N + in the cationic surface active agent can also form a stable association body for alpha-gallic acid and beta-gallic acid brass to jointly act on bacteria and viruses.

Description

Technical Field

[0001] The present invention relates to the technical field of plant fungicides, and in particular, to a long-acting plant fungicide. Background Art

[0002] Fungicides are currently widely used in people's daily lives, and there are an endless stream of commonly used fungicides. For example, Bordeaux liquid, chlorine dioxide, etc. all have good disinfection effects, but their strong pungent odors and corrosive oxidizing properties are very inconvenient to use; chlorine dioxide fungicide is very unstable in aqueous solution and is sensitive to light. Conventional chlorine dioxide disinfectant or disinfection tablet solution quickly disappears when coated on items, failing to achieve the effect of disinfection and sterilization.

[0003] Hydrogen peroxide-based disinfection fungicides also have obvious bactericidal effects, but hydrogen peroxide is unstable and easily decomposed, which is also not ideal in use. Hydrogen peroxide decomposes continuously, accumulating oxygen significantly in a closed storage container to generate pressure. A low concentration has a poor bactericidal rate, and a high concentration is highly corrosive to the skin, making it somewhat dangerous to use. Heavy metal silver, copper, and zinc ions have a certain bactericidal effect, but they are only effective at relatively high concentrations. At the same time, heavy metals have a certain cumulative and potential harm to people's bodies.

[0004] Currently, although there are also some plant antibacterial disinfectants, most of them focus on plant extracts such as honeysuckle, mugwort, chinaberry fruit, isatis root, houttuynia cordata, pomegranate peel, etc., and are applied to fields such as laundry detergent, fabrics, air purification, and cosmetics. However, experiments have found that myrtle extract, wormwood extract, and rose extract with antibacterial effects become turbid after being dissolved in water, which becomes obvious after three days, with wormwood being the least and myrtle being the most, and it is impossible to obtain a clear, transparent, and stable antibacterial solution.

[0005] Therefore, the fungicides in the prior art cannot meet people's requirements for safety and stability. Summary of the Invention

[0006] The main object of the present invention is to provide a long-acting plant fungicide to solve the technical problem that the fungicides in the related art cannot meet people's requirements for safety and stability.

[0007] To achieve the above object, according to one aspect of the present invention, there is provided a long-acting plant fungicide, which comprises the following components by weight percentage: Stemona sessilifolia Miq. extract 0.5 - 3%; Calendula officinalis L. extract 0.5 - 3%; Myrrh extract 0.5 - 3%; Phellodendron amurense Rupr. extract 0.5 - 3%; cationic surfactant 0.05 - 0.5%; water 87.5 - 97.95%.

[0008] Further, the cationic surfactant is alkyl[(phenylethyl)methyl]dimethylammonium chloride.

[0009] Further, the conductivity of the water is less than 5×10-6 mΩ.cm-1.

[0010] Further, the weight percentage of the Stemona tuberosa extract is 1.8%.

[0011] Further, the weight percentage of the Calendula officinalis extract is 2%.

[0012] Further, the weight percentage of the Myrrh extract is 1.5%.

[0013] Further, the weight percentage of the Phellodendron amurense extract is 2.2%.

[0014] Further, the weight percentage of the surfactant is 0.3%.

[0015] Further, the water is deionized water or distilled water.

[0016] When applying the long-acting plant bactericide of the present invention, by combining the Stemona tuberosa extract, Calendula officinalis extract, Myrrh extract and Phellodendron amurense extract, the effective compounds in the Stemona tuberosa extract, Calendula officinalis extract, Myrrh extract and Phellodendron amurense extract form hydrogen bonds in the forms of -OH-O- and -OH-N-H, generating a synergistic effect, thereby achieving a strong bactericidal and disinfection effect; by using the alkaloids contained in Stemona tuberosa, berberine and magnoflorine in Phellodendron amurense and the polysaccharide amino acids in Stemona tuberosa and myrrholic acid in Myrrh can form stable acid-base aggregates, which act on bacteria and viruses jointly, thereby achieving the killing effect on bacteria and viruses; through the significant dispersion and solubilization effect of the cationic surfactant on flavonoids and resins in natural plant extracts, a stable and clear solution can be formed. At the same time, R4-N+ in the cationic surfactant can also form stable aggregates with α-myrrholic acid and β-myrrholic acid flavonoids and act on bacteria and viruses jointly. Specific Embodiments

[0017] The following description of at least one exemplary embodiment is merely illustrative in nature and is in no way intended to limit the present invention, its application, or its use. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the scope of protection of the present invention.

[0018] It should be noted that the terms used herein are only for the purpose of describing specific embodiments and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprising" and / or "including" are used in this specification, they specify the presence of features, steps, operations, devices, components, and / or combinations thereof.

[0019] In order to solve the technical problem that the fungicides in the prior art cannot meet people's requirements for safety and stability, the present application provides a long-acting plant fungicide.

[0020] The first embodiment of the present application provides a long-acting plant fungicide, which comprises the following components by weight percentage: 0.5-3% of Stemona sessilifolia extract; 0.5-3% of Calendula officinalis extract; 0.5-3% of Myrrh extract; 0.5-3% of Phellodendron amurense extract; 0.05-0.5% of cationic surfactant; 87.5-97.95% of water.

[0021] The Stemona sessilifolia extract, Calendula officinalis extract, Myrrh extract and Phellodendron amurense extract described in the present application all belong to natural plant extracts. Stemona sessilifolia contains alkaloids, which are a class of nitrogen-containing heterocyclic compounds composed of one or more nitrogen atoms. Phellodendron amurense contains berberine and magnoflorine. Among them, berberine is an isoquinoline alkaloid in plants, which strongly inhibits the biofilm of Staphylococcus aureus. Berberine has an effect of removing the R plasmid of a variety of drug-resistant Escherichia coli, and can destroy the integrity of the cell membrane structure of Escherichia coli. The change of membrane permeability will lead to lower drug resistance of Escherichia coli; Calendula officinalis extract contains flavonoids, which can significantly damage the bacterial cell membrane, resulting in the leakage of intracellular substances such as ATP and proteins, and causing significant changes in the bacterial morphology, thereby leading to the death of the bacteria.

[0022] The disinfectant provided in the present application utilizes the alkaloids in Stemona sessilifolia, berberine and magnoflorine in Phellodendron amurense, and the polysaccharide amino acids in Stemona sessilifolia and myrrhanic acid in Myrrh to form a stable acid-base association body, which acts on bacteria and viruses jointly, so as to achieve the effect of killing and disinfecting bacteria and viruses. The effective compounds in Stemona sessilifolia extract, Calendula officinalis extract, Myrrh extract and Phellodendron amurense extract form hydrogen bonds in the form of -OH-O- and -OH-N-H, producing a synergistic effect, so as to achieve a strong bactericidal and disinfection effect; the cationic surfactant has a significant dispersion and solubilization effect on flavonoids and resins in natural plant extracts, and can form a stable and clear solution. At the same time, R4-N+ in the cationic surfactant can also form a stable association body with α-myrrhanic acid and β-myrrhanic acid flavonoids, and act on bacteria and viruses jointly.

[0023] Further, the cationic surfactant is alkyl[(phenylethyl)methyl]dimethylammonium chloride. By adding the cationic surfactant, the mixture can be made uniform and stable, and it is more uniformly dispersed in air atomization, on the skin and on the surface of objects. At the same time, when alkyl[(phenylethyl)methyl]dimethylammonium chloride is selected as the surfactant, it also has a certain bactericidal effect. While achieving surface activity, it can further improve the bactericidal ability. Preferably, the weight percentage of the surfactant is 0.3%.

[0024] In a specific embodiment of the present application, the Stemona extract is obtained by using the roots of plants of the family Stemonaceae, washing, chopping them, and through processes such as biochemical extraction, concentration, clarification, and membrane filtration. It has a bactericidal effect. Preferably, the weight percentage of the Stemona extract is 1.8%. In the present application, the Stemona extract described can be a commercially available Stemona extract.

[0025] In another specific embodiment of the present application, the Calendula extract is extracted from the flowers, leaves, and roots of Calendula officinalis, and contains saponins, flavonoids, and triterpenoids. It has anti-inflammatory and antibacterial effects, especially better effects against Staphylococcus and Streptococcus, and also has a significant inhibitory effect on fungi and viruses. Preferably, the usage amount of the Calendula extract is 2%. In the present application, the Calendula extract described can be a commercially available Calendula extract.

[0026] Furthermore, Myrrh is mainly produced in Africa and contains resin, volatile oil, α-boswellic acid, and β-boswellic acid. It has an antibacterial effect and an inhibitory effect on 5-α reductase, and can treat acne. Preferably, the usage amount of the Myrrh extract is 1.5%. In the present application, the Myrrh extract described can be a commercially available Myrrh extract.

[0027] In another embodiment, the Phellodendron extract is extracted from the dried bark of the plant Phellodendron chinense Schneid. of the Rutaceae family, and is obtained through processes such as biochemical extraction, concentration, clarification, and membrane filtration. It contains berberine, magnoflorine, syringin, phellodendrine, N-methylharman, phellodendrone, etc., and has obvious antibacterial and bactericidal effects, especially obvious effects against Staphylococcus aureus, Streptococcus pneumoniae, Corynebacterium diphtheriae, and Bacillus dysenteriae. Preferably, the usage amount of the Phellodendron extract is 2.2%. In the present application, the Phellodendron extract described can be a commercially available Phellodendron extract.

[0028] To ensure the disinfection effect, the water described in the present application is high-purity water with a conductivity less than 5×10-6 mΩ·cm-1. Preferably, the water can be deionized water or distilled water, which is beneficial to further ensuring the disinfection and sterilization effect.

[0029] The following verifies and explains the disinfection effects of disinfectants with different component ratios:

[0030] Example 1

[0031] The ratio of the natural plant bactericidal disinfectant (weight percentage) is:

[0032]

[0033] Mix for 5 minutes. According to the National Disinfection Technical Specification (2002 Edition), use the suspension method for testing. Take the average value of three tests. The killing rate of Escherichia coli reaches 99.22%, and the killing rate of Staphylococcus aureus reaches 98.26%.

[0034] Example 2

[0035] The ratio of the natural plant germicidal disinfectant (by weight percentage) is as follows:

[0036]

[0037] Mix for 5 minutes. According to the National Disinfection Technical Specification (2002 Edition), use the suspension method for testing. Take the average value of three tests. The killing rate of Escherichia coli reaches 99.68%, and the killing rate of Staphylococcus aureus reaches 99.16%.

[0038] Example 3

[0039] The ratio of the natural plant germicidal disinfectant (by weight percentage) is as follows:

[0040]

[0041] Mix for 5 minutes. According to the National Disinfection Technical Specification (2002 Edition), use the suspension method for testing. For the average value of three tests, the killing rate of Escherichia coli reaches 99.92%, and the killing rate of Staphylococcus aureus reaches 99.90%.

[0042] Example 4

[0043] The ratio of the natural plant germicidal disinfectant (by weight percentage) is as follows:

[0044]

[0045] Mix for 5 minutes. According to the National Disinfection Technical Specification (2002 Edition), use the suspension method for testing. For the average value of three tests, the killing rate of Escherichia coli reaches 99.99%, and the killing rate of Staphylococcus aureus reaches 99.99%.

[0046] Example 5

[0047] The ratio of the natural plant germicidal disinfectant (by weight percentage) is as follows:

[0048]

[0049]

[0050] Mix for 5 minutes. According to the National Disinfection Technical Specification (2002 Edition), use the suspension method for testing. For the average value of three tests, the killing rate of Escherichia coli reaches 99.999%, and the killing rate of Staphylococcus aureus reaches 99.999%.

[0051] Example VI

[0052] The ratio of the natural plant germicidal disinfectant (by weight percentage) is as follows:

[0053]

[0054] Mix for 5 minutes. According to the national disinfection technical specification (2002 edition), using the suspension method for testing, the average value of three tests shows that the killing rate of Escherichia coli reaches 99.96%, and the killing rate of Staphylococcus aureus reaches 99.92%.

[0055] Example VII

[0056] The ratio of the natural plant germicidal disinfectant (by weight percentage) is as follows:

[0057]

[0058] Mix for 5 minutes. According to the national disinfection technical specification (2002 edition), using the suspension method for testing, the average value of three tests shows that the killing rate of Escherichia coli reaches 99.999%, and the killing rate of Staphylococcus aureus reaches 99.999%.

[0059] During the use of the disinfectant provided by this application, it is applicable to disinfection and sterilization in a variety of different scenarios. For example, it can be used for the disinfection of general object surfaces, hard object surfaces, fabrics, and porous object surfaces, and can also be used for the disinfection of skin, hands, tableware, or indoor air, etc.

[0060] During the use process, for object surfaces or fabric surfaces, wiping, spraying, etc. can be used, and the action time is more than 2 minutes; for tableware, soaking, etc. can be used, and the action time is more than 10 minutes; for skin and hands, wiping, etc. can be used, and the action time is more than 1 minute; for indoor air, atomization, etc. can be used. The liquid medicine is atomized through equipment such as atomizers or humidifiers and then sprayed into the indoor air to reach a concentration of 10 ml / m 3 Concentration, and the standard of qualified disinfection can be achieved after acting for 1 hour.

[0061] From the above description, it can be seen that the above embodiments of the present invention achieve the following technical effects:

[0062] 1. Effectively solve the technical problem that the germicides in the related technical fields cannot meet people's requirements for safety and stability;

[0063] 2. Can be applicable to the disinfection and sterilization of air, environment, object surfaces, human bodies, and hospitals. This product is safe and long - acting for the human body.

[0064] The above are only the preferred embodiments of the present invention and are not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A long-acting plant fungicide, characterized in that: The following components are included in weight percentage: Stemona bifolia extract 0.5-3%; Calendula officinalis extract 0.5-3%; Myrrh extract 0.5-3%; Phellodendron amurense extract 0.5-3%; Cationic surfactant 0.05-0.5%; Water 87.5-97.95%.

2. The long-acting plant fungicide according to claim 1, characterized in that: The cationic surfactant is alkyl[(phenylethyl)methyl]dimethylammonium chloride.

3. The long-acting plant fungicide according to claim 1, characterized in that: The electrical conductivity of the water is less than 5×10 -6 mΩ.cm -1 .

4. The long-acting plant fungicide according to claim 1, characterized in that: The weight percentage of the Stemona bifolia extract is 1.8%.

5. The long-acting plant fungicide according to claim 1, characterized in that: The weight percentage of the marigold extract is 2%.

6. The long-acting plant fungicide according to claim 1, characterized in that: The weight percentage of the myrrh extract is 1.5%.

7. The long-acting plant fungicide according to claim 1, characterized in that: The weight percentage of the Phellodendron chinense extract is 2.2%.

8. The long-acting plant fungicide according to claim 1, characterized in that: The weight percentage of the surfactant is 0.3%.

9. The long-acting plant fungicide according to claim 1, characterized in that: The water is deionized water or distilled water.

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