A folding bag for anesthesia machine and its injection molding process

Abstract

The present invention discloses a folding capsule for an anesthesia machine and its injection molding process, relating to the technical field of folding capsules. The folding capsule for an anesthesia machine comprises the following raw materials in parts by weight: 50 parts natural rubber latex, 50 parts chloroprene latex, 1-3 parts stabilizer, 1-2 parts sodium p-styrene sulfonate aqueous solution, 3-5 parts nano-silica suspension, 2-3 parts antioxidant, 5-8 parts toughening agent, 5-10 parts sulfur, 4-8 parts zinc oxide, 5-10 parts accelerator, and 3-6 parts peregal O-20. The folding capsule prepared by the present invention has good tensile strength, aging resistance, and tear resistance.

Description

Technical Field

[0001] The present invention relates to the technical field of folding bladders, and in particular to a folding bladder for an anesthesia machine and an injection molding process thereof. Background Art

[0002] Anesthesia machines are essential equipment in modern medical surgery, providing patients with a stable mixture of anesthetic gases and oxygen during surgery. As a core component of an anesthesia machine, the pleated bladder is primarily used for gas storage, delivery, and manual ventilation. The pleated bladder (also known as a bellows) undergoes repeated expansion and contraction during operation, placing extremely high demands on the material's flexibility, durability, and sealing properties.

[0003] Currently, pleated bladders used in anesthesia machines are primarily made from rubber or silicone materials through a vulcanization process. While these materials offer excellent elasticity and sealing properties, they still present several practical challenges. Traditional rubber or silicone pleated bladders are prone to aging and cracking after long-term use. This is especially true when subjected to frequent expansion and contraction and exposure to anesthetic gases. The materials' insufficient chemical stability and fatigue resistance shorten their service life. Existing bladders often utilize a simple bellows structure, which results in uneven stress distribution during repeated expansion and contraction, making fatigue fractures more likely to occur at the bends.

[0004] Chinese invention patent application with publication number CN118165385A discloses a polyisoprene rubber air storage bag. The air storage bag prepared by the polyisoprene rubber air storage bag has good mechanical properties and antistatic properties, but poor tear resistance. Summary of the Invention

[0005] In view of the deficiencies in the prior art, the present invention aims to provide a folding bag for an anesthesia machine and an injection molding process thereof.

[0006] To achieve the above object, the present invention is implemented through the following technical solutions:

[0007] A foldable capsule for an anesthesia machine, comprising the following raw materials in parts by weight:

[0008] Natural rubber latex: 50 parts, chloroprene latex: 50 parts, stabilizer: 1-3 parts, sodium p-styrene sulfonate aqueous solution: 1-2 parts, nano-silicon dioxide suspension dispersion: 3-5 parts, antioxidant: 2-3 parts, toughening agent: 5-8 parts, sulfur: 5-10 parts, zinc oxide: 4-8 parts, accelerator: 5-10 parts, peregal O-20: 3-6 parts;

[0009] The antioxidant is prepared by the following method:

[0010] S1: Pentaerythritol reacts with 3,6-dimethyl-1,4-dioxane-2,5-dione under the catalysis of stannous octoate to form a four-arm star-shaped compound;

[0011] S2: A four-arm star-shaped compound reacts with 4-(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenoxy)-4-oxobutanoic acid in the presence of p-toluenesulfonic acid to generate an antioxidant.

[0012] In the step S1, the mass ratio of pentaerythritol to 3,6-dimethyl-1,4-dioxane-2,5-dione is 1:(18-20).

[0013] In step S2, the molar ratio of the four-arm star compound to 4-(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenoxy)-4-oxobutanoic acid is 1:(2-3).

[0014] The toughening agent is prepared by the following method:

[0015] A1: Oleic acid reacts with formic acid and H2O2 to form epoxy compounds;

[0016] A2: Epoxy compounds generate polyester compounds under the action of chromium acetylacetonate;

[0017] A3: A polyester compound reacts with isophorone diisocyanate in the presence of dibutyltin dilaurate to form an isocyanate-terminated polymer.

[0018] A4: The isocyanate-terminated polymer reacts with the amino-terminated silicone oil to form a toughening agent.

[0019] In step A1, the feed mass ratio of oleic acid to formic acid is 16:5; in step A2, the feed mass ratio of epoxy compound to chromium acetylacetonate is 50:1; in step A3, the feed mass ratio of polyester compound to isophorone diisocyanate is 10:1; and in step A4, the feed mass ratio of terminal isocyanate polymer to terminal amino silicone oil is 6:1.

[0020] The stabilizer is a 10-25 wt% potassium hydroxide aqueous solution.

[0021] The accelerator is one of accelerator TMTD and accelerator BZ.

[0022] The mass concentration of the sodium p-styrenesulfonate aqueous solution is 25-30wt%.

[0023] The antioxidant, toughening agent, sulfur, zinc oxide, accelerator, and peregal O-20 are all aqueous dispersions with a total solid content of 50 wt %. The aqueous dispersions are all ground using a nano-abrasive mill until the dispersion D90 is no greater than 3 microns, and 0.6 wt % of disodium methylene dinaphthalenesulfonate is added to the ground aqueous dispersion as a surfactant.

[0024] An injection molding process for a folding bag for an anesthesia machine comprises the following steps:

[0025] (1) Weigh by weight: natural rubber latex: 50 parts, chloroprene rubber latex: 50 parts, stabilizer: 1-3 parts, sodium p-styrene sulfonate aqueous solution: 1-2 parts, nano-silica suspension dispersion: 3-5 parts, antioxidant: 2-3 parts, toughening agent: 5-8 parts, sulfur: 5-10 parts, zinc oxide: 4-8 parts, accelerator: 5-10 parts, and peregal O-20: 3-6 parts;

[0026] (2) The above raw materials were stirred and mixed, kept warm at 45°C, pre-cured for 1.5 hours, and then allowed to stand at room temperature for 48 hours to obtain a matured latex;

[0027] (3) Clean the mold, dry it at 80°C for 5 minutes; soak it in 20wt% calcium nitrate aqueous solution, and dry the coagulant at 90°C for 5 minutes;

[0028] (4) The latex was soaked and dried at 80°C for 5 minutes; the latex was leached at 60±5°C and curled; the curled latex was dried and vulcanized at 110°C for 25 minutes; the latex was demoulded, washed with hot water at 60°C, and then leached and post-processed to obtain a folding capsule for anesthesia machine.

[0029] Due to the adoption of the above technical solution, the beneficial effects of the present invention include:

[0030] (1) The antioxidant prepared by the present invention combines a four-arm star-shaped core with multiple antioxidant functional groups to achieve synergistic optimization of anti-aging performance and mechanical properties. It not only enhances the free radical capture efficiency and thermal stability, but also improves the tensile properties through the flexibility of the molecular chain and the cross-linking network. It is particularly suitable for folding capsule materials under high dynamic stress environments.

[0031] (2) The toughening agent prepared by the present invention provides the folding capsule with excellent fatigue resistance and toughness through the synergistic effect of polyester and flexible silicone, meeting the core requirements of repeated deformation, environmental tolerance and long-term stability in the application of the folding capsule. DETAILED DESCRIPTION

[0032] The present invention will be further described below with reference to the embodiments, but the present invention is not limited to these embodiments.

[0033] Example 1 Preparation of antioxidant:

[0034] S1: Under nitrogen protection, 1000g DMF, 10g pentaerythritol and 180g 3,6-dimethyl-1,4-dioxane-2,5-dione were added to the reactor, stirred and mixed, heated to 130°C, stirred for 15min, and then 10g of catalyst stannous octoate was added. After reacting for 20h, the temperature was cooled to room temperature and distilled under reduced pressure at 60°C for 2h to obtain a crude product. The crude product was added to 500ml chloroform and stirred, and then 500ml cold methanol was added and allowed to stand to precipitate. The product was then washed three times with methanol (300ml each time) and dried under vacuum at 60°C for 5h to obtain a four-arm star compound with a number average molecular weight of 1864. The reaction equation is as follows:

[0035] .

[0036] S2: Under nitrogen protection, 1200g toluene, 0.1mol four-arm star compound, and 0.2mol 4-(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propane-2-ylthio)phenoxy)-4-oxobutanoic acid were added to the reactor, stirred and mixed, and the temperature was raised to 80°C. Then, 15g p-toluenesulfonic acid was added and reacted for 6h (a water separator was used to remove the generated water during the reaction). After cooling to room temperature, saturated sodium bicarbonate solution was slowly added to adjust the pH to neutral. The mixture was stirred for 30min, allowed to stand and separate, and the organic phase was transferred to a rotary evaporator. The mixture was distilled under reduced pressure at 60°C for 4h and dried under vacuum at 70°C for 10h to obtain an antioxidant; the number average molecular weight was 3096, and the reaction equation was as follows:

[0037] .

[0038] During the reaction, some hydroxyl groups of the four-arm star compound undergo esterification reaction with the carboxylic acid of 4-(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenoxy)-4-oxobutanoic acid.

[0039] Example 2 Preparation of antioxidant:

[0040] S1: Under nitrogen protection, 1000g DMF, 10g pentaerythritol and 190g 3,6-dimethyl-1,4-dioxane-2,5-dione were added to the reactor, stirred and mixed, heated to 130°C, stirred for 15min, and then 10g of catalyst stannous octoate was added. After reacting for 24h, the temperature was cooled to room temperature and distilled under reduced pressure at 60°C for 2h to obtain a crude product. The crude product was added to 500ml chloroform and stirred, and then 500ml cold methanol was added and allowed to stand to precipitate. The precipitate was then washed three times with methanol (300ml each time) and dried under vacuum at 60°C for 5h to obtain a four-arm star compound with a number average molecular weight of 2152;

[0041] S2: Under nitrogen protection, 1200g of toluene, 0.1mol of four-arm star compound, and 0.25mol of 4-(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propane-2-ylthio)phenoxy)-4-oxobutanoic acid were added to the reactor, stirred and mixed, and the temperature was raised to 90°C. Then, 15g of p-toluenesulfonic acid was added, and the reaction was continued for 5h (a water separator was used to remove the generated water during the reaction). The reaction was cooled to room temperature, and a saturated sodium bicarbonate solution was slowly added to adjust the pH to neutral. The mixture was stirred for 30min, allowed to stand and separate, and the organic phase was transferred to a rotary evaporator. The mixture was distilled under reduced pressure at 60°C for 4h and dried under vacuum at 70°C for 10h to obtain an antioxidant with a number average molecular weight of 3692.

[0042] Example 3 Preparation of antioxidant:

[0043] S1: Under nitrogen protection, 1000g DMF, 10g pentaerythritol and 200g 3,6-dimethyl-1,4-dioxane-2,5-dione were added to the reactor, stirred and mixed, heated to 130°C, stirred for 15min, then 10g stannous octoate catalyst was added, reacted for 26h, cooled to room temperature, and distilled under reduced pressure at 60°C for 2h to obtain a crude product. The crude product was added to 500ml chloroform and stirred, then 500ml cold methanol was added, and the precipitate was allowed to stand. The precipitate was then washed three times with methanol (300ml each time) and dried under vacuum at 60°C for 5h to obtain a four-arm star compound; the number average molecular weight was 2440;

[0044] S2: Under nitrogen protection, 1200g of toluene, 0.1mol of four-arm star compound, and 0.3mol of 4-(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propane-2-ylthio)phenoxy)-4-oxobutanoic acid were added to the reactor, stirred and mixed, and the temperature was raised to 100°C. Then, 15g of p-toluenesulfonic acid was added. After reacting for 4h (a water separator was used to remove the generated water during the reaction), the mixture was cooled to room temperature, and a saturated sodium bicarbonate solution was slowly added to adjust the pH to neutral. The mixture was stirred thoroughly for 30min, allowed to stand and separate, and the organic phase was transferred to a rotary evaporator. The mixture was distilled under reduced pressure at 60°C for 4h and dried under vacuum at 70°C for 10h to obtain an antioxidant with a number average molecular weight of 4288.

[0045] Example 4 Preparation of toughening agent:

[0046] A1: Add 800 ml of DMF, 160 g of oleic acid, and 10 g of a strong acid cation exchange resin to a reactor, stir and mix thoroughly, and heat to 50°C. Then, mix 50 g of formic acid and 160 g of a 30 wt% H2O2 solution. Slowly add the mixed solution of formic acid and H2O2 dropwise for 20 minutes. After reacting for 8 hours, cool to room temperature, transfer the supernatant to a separatory funnel, let it stand, discard the inorganic liquid below, and extract three times with petroleum ether (200 ml each time). Distill under reduced pressure at 50°C for 5 hours to obtain an epoxy compound. The reaction equation is as follows:

[0047] .

[0048] A2: Add 500 g of epoxy compound and 10 g of chromium acetylacetonate to a reactor, stir, heat to 170°C and react for 5 h, cool to room temperature, add 800 ml of methanol, stir, precipitate, filter, and vacuum dry at 50°C for 3 h to obtain a polyester compound. The reaction equation is as follows:

[0049] .

[0050] A3: Under nitrogen protection, 500 g of DMF and 100 g of polyester compound were added to the reactor, stirred and mixed, and the temperature was raised to 70°C. Then, 10 g of isophorone diisocyanate was slowly added dropwise over 20 min. After the addition was complete, 5 g of dibutyltin dilaurate as a catalyst was added and the reaction was carried out for 6 h. Then, 500 ml of ice water was added for precipitation, filtered, and dried in vacuo at 40°C for 12 h to obtain an isocyanate-terminated polymer. The reaction equation is shown below:

[0051] .

[0052] A4: Under nitrogen protection, 500g of DMF and 60g of isocyanate-terminated polymer were added to the reactor, stirred and mixed, and the temperature was raised to 70°C. Then, 10g of amino-terminated silicone oil and 5g of dibutyltin dilaurate (catalyst) were added. The reaction was carried out for 6h. Then, 500ml of ice water was added for precipitation, filtered, and vacuum dried at 40°C for 12h to obtain a toughening agent. During this reaction, the isocyanate groups in the isocyanate-terminated polymer reacted with the amino groups in the amino-terminated silicone oil.

[0053] Example 5 Preparation of foldable capsule for anesthesia machine:

[0054] (1) Weigh: natural rubber latex: 500 g, chloroprene rubber latex: 500 g, stabilizer (10 wt% potassium hydroxide aqueous solution): 10 g, sodium p-styrene sulfonate aqueous solution (25 wt%): 10 g, nano-silica suspension dispersion: 30 g, antioxidant (prepared in Example 1): 20 g, toughening agent (prepared in Example 4): 50 g, sulfur: 50 g, zinc oxide: 40 g, accelerator (accelerator TMTD): 50 g, and peregal O-20: 30 g;

[0055] (2) The above raw materials were stirred and mixed, kept warm at 45°C, pre-cured for 1.5 hours, and then allowed to stand at room temperature for 48 hours to obtain a matured latex;

[0056] (3) Clean the mold, dry it at 80°C for 5 minutes; soak it in 20wt% calcium nitrate aqueous solution, and dry the coagulant at 90°C for 5 minutes;

[0057] (4) The latex was soaked and dried at 80°C for 5 minutes; the latex was leached at 60±5°C and curled; the curled latex was dried and vulcanized at 110°C for 25 minutes; the latex was demoulded, washed with hot water at 60°C, leached and dried at 40°C to obtain a folding capsule for an anesthesia machine.

[0058] Example 6 Preparation of foldable capsule for anesthesia machine:

[0059] (1) Weigh: natural rubber latex: 500g, chloroprene rubber latex: 500g, stabilizer (15wt% potassium hydroxide aqueous solution): 20g, sodium p-styrene sulfonate aqueous solution (28wt%): 15g, nano-silica suspension dispersion: 40g, antioxidant (prepared in Example 2): 25g, toughening agent (prepared in Example 4): 60g, sulfur: 80g, zinc oxide: 60g, accelerator (accelerator TMTD): 80g, and peregal O-20: 50g;

[0060] (2) The above raw materials were stirred and mixed, kept warm at 45°C, pre-cured for 1.5 hours, and then allowed to stand at room temperature for 48 hours to obtain a matured latex;

[0061] (3) Clean the mold, dry it at 80°C for 5 minutes; soak it in 20wt% calcium nitrate aqueous solution, and dry the coagulant at 90°C for 5 minutes;

[0062] (4) The latex was soaked and dried at 80°C for 5 minutes; the latex was leached at 60±5°C and curled; the curled latex was dried and vulcanized at 110°C for 25 minutes; the latex was demoulded, washed with hot water at 60°C, leached and dried at 40°C to obtain a folding capsule for an anesthesia machine.

[0063] Example 7 Preparation of foldable capsule for anesthesia machine:

[0064] (1) Weigh: natural rubber latex: 500g, chloroprene rubber latex: 500g, stabilizer (25wt% potassium hydroxide aqueous solution): 30g, sodium p-styrene sulfonate aqueous solution (30wt%): 20g, nano-silica suspension dispersion: 50g, antioxidant (prepared in Example 3): 30g, toughening agent (prepared in Example 4): 80g, sulfur: 100g, zinc oxide: 80g, accelerator (accelerator BZ): 100g, and peregal O-20: 60g;

[0065] (2) The above raw materials were stirred and mixed, kept warm at 45°C, pre-cured for 1.5 hours, and then allowed to stand at room temperature for 48 hours to obtain a matured latex;

[0066] (3) Clean the mold, dry it at 80°C for 5 minutes; soak it in 20wt% calcium nitrate aqueous solution, and dry the coagulant at 90°C for 5 minutes;

[0067] (4) The latex was soaked and dried at 80°C for 5 minutes; the latex was leached at 60±5°C and curled; the curled latex was dried and vulcanized at 110°C for 25 minutes; the latex was demoulded, washed with hot water at 60°C, leached and dried at 40°C to obtain a folding capsule for an anesthesia machine.

[0068] Comparative Example 1

[0069] The raw material components and proportions of the folding capsule are basically the same as those in Example 6, except that the antioxidant is replaced with an antioxidant of equal mass prepared by the following method:

[0070] The preparation method of the antioxidant is basically the same as that of Example 2, except that the pentaerythritol in step S1 is replaced by an equal weight of 1,4-butanediol.

[0071] Comparative Example 2

[0072] The raw material components and proportions of the folding capsule are basically the same as those in Example 6, except that the antioxidant is replaced with an antioxidant of equal mass prepared by the following method:

[0073] The preparation method of the antioxidant is basically the same as that of Example 2, except that the amount of 4-(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propane-2-ylthio)phenoxy)-4-oxobutanoic acid added in step S2 is 0.4 mol.

[0074] Comparative Example 3

[0075] The raw material components and proportions of the folding capsule are basically the same as those in Example 6, except that the antioxidant is replaced with an antioxidant of equal mass prepared by the following method:

[0076] The preparation method of the antioxidant is basically the same as that in Example 2, except that the 4-(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propane-2-ylthio)phenoxy)-4-oxobutanoic acid in step S2 is replaced by an equimolar amount of 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionic acid.

[0077] Comparative Example 4

[0078] The raw material components and proportions of the folding capsule are basically the same as those in Example 6, except that the toughening agent is replaced with an equal mass of toughening agent prepared by the following method:

[0079] The preparation method of the toughening agent is basically the same as that of Example 4, except that the polyester compound in step A3 is replaced by an equal weight of castor oil.

[0080] Comparative Example 5

[0081] The raw material components and proportions of the folding capsule are basically the same as those of Example 6, except that the toughening agent is replaced by an equal mass of the isocyanate-terminated polymer prepared in Step A3 of Example 4.

[0082] Comparative Example 6

[0083] The raw material components and proportions of the folding capsule are basically the same as those in Example 6, except that the toughening agent is replaced with an equal mass of toughening agent prepared by the following method:

[0084] The preparation method of the toughening agent is basically the same as that of Example 4, except that the amino-terminated silicone oil in step A4 is replaced by an equal weight of hexamethylenediamine.

[0085] It should be noted that the antioxidant, toughening agent, sulfur, zinc oxide, accelerator, and peregal O-20 used in Examples 5-7 and the comparative example of the present application are all aqueous dispersions with a total solid content of 50 wt%; the preparation method of the aqueous dispersion is as follows: the above-mentioned antioxidant, toughening agent, sulfur, zinc oxide, accelerator, and peregal O-20 are mixed with an equal weight of water, and then 0.6 wt% of the total weight of the aqueous dispersion is added as a surfactant, and the dispersion is ground using a nano-abrasive mill until the D90 is not greater than 3 microns to obtain an aqueous dispersion with a total solid content of 50 wt%.

[0086] The nano-silica suspension dispersion used in the examples and comparative examples of the present application is SS-S10WJ type produced by Hangzhou Jikang New Materials Co., Ltd., and the silica particle size is 8-15 nm, and the concentration is 30wt% of the aqueous dispersion; the natural latex is IR-550 natural latex produced by Puyang Linshi Chemical New Materials Co., Ltd., with a solid content of 50wt%; the chloroprene latex is SKYPRENE LATEX LA-502, with a solid content of 50wt%; the sulfur is S-80 type special sulfur powder produced by Qingdao Luchuan Chemical Co., Ltd., with a mesh size of 400 mesh; the amino-terminated silicone oil model is Cheersil 8110, produced by Suzhou Qitian New Materials Co., Ltd.

[0087] Unless otherwise specified, the weights used in Examples 5-7 and the comparative examples herein are the weights of the aqueous dispersions. For example, in Example 6, the 500g natural rubber latex weighed represents 500g of natural rubber latex with a solids content of 50wt%, and the effective weight of the natural rubber latex is 250g. The 25g antioxidant weighed represents a 50wt% aqueous dispersion of the antioxidant, and the effective weight of the antioxidant is 12.5g.

[0088] The folding bags of Examples 5-7 and Comparative Examples 1-6 of the present application were subjected to tensile strength and elongation at break performance tests according to ASTM D412-16 (2021), and the tear strength was tested according to GB / T 529-2008, trouser tear method. The test results are shown in Table 1.

[0089] Aging test: The folding capsules of Examples 5-7 and Comparative Examples 1-6 of the present application were placed in a hot air aging box and aged at 100° C. for 5 days, and then relevant performance tests were performed. The test results are shown in Table 1.

[0090] Table 1 Performance data

[0091]

[0092] It can be seen from Examples 5, 6 and 7 in Table 1 that the foldable capsule of the present invention has excellent mechanical properties, anti-aging properties and tear resistance.

[0093] The antioxidant prepared by the present invention has a four-arm star topology. The four-arm structure with pentaerythritol as the core gives the antioxidant a higher molecular weight and three-dimensional steric hindrance. At the same time, the four-arm star topology is tightly bound to the base material through physical entanglement and polar interaction, significantly reducing its migration rate in the polymer matrix and improving its migration resistance. In addition, the multi-arm design of the star structure makes the antioxidant group more evenly distributed, with a moderate local concentration, to avoid agglomeration. The thioether group can decompose peroxides, form a synergistic effect with the phenolic hydroxyl group, inhibit thermal oxidation degradation, delay yellowing and embrittlement of the material, and significantly improve antioxidant efficiency. The thioether group plays a stress relaxation role to a certain extent, reducing stress concentration. The introduction of polyester chain segments can improve the flexibility of the material, avoid local fracture, and thus enhance tensile strength and elongation at break.

[0094] The urethane and urea bonds in the toughening agent prepared by this invention form a strong hydrogen bond network. These hydrogen bonds can reversibly break and reform under external force, preventing direct tearing caused by stress concentration and significantly improving the material's elongation at break. The siloxane backbone introduced into the toughening agent has extremely low rotational steric hindrance, and the low glass transition temperature of the siloxane chain imparts low-temperature toughness to the material, making the folding capsule less susceptible to brittle fracture during repeated folding. Furthermore, the molecular chain slippage of the siloxane chain absorbs mechanical energy, improving fatigue resistance.

[0095] In comparative example 1, after replacing pentaerythritol with 1,4-butanediol, since it contains only two hydroxyl groups (far less than the four hydroxyl groups of pentaerythritol), the synthesized antioxidant cannot form a four-arm star-shaped cross-linked structure, its dispersion performance and free radical capture efficiency are reduced, and its anti-aging performance is reduced.

[0096] In comparative example 2, too many hindered phenol anti-aging groups were grafted, and the molecular volume increased, which reduced its dispersion performance in the compounded system, thereby causing uneven distribution of hindered phenol and deterioration of anti-aging performance.

[0097] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. However, any equivalent changes, modifications and evolutions made by ordinary technicians in this field without departing from the scope of the technical solution of the present invention by using the technical content disclosed above are all equivalent embodiments of the present invention. At the same time, any equivalent changes, modifications and evolutions made to the above embodiments based on the essential technology of the present invention are still within the scope of protection of the technical solution of the present invention.

Claims

1. A folding bag for an anesthesia machine, characterized in that: The composition comprises the following raw materials in parts by weight: Natural rubber latex: 50 parts, chloroprene latex: 50 parts, stabilizer: 1-3 parts, sodium p-styrene sulfonate aqueous solution: 1-2 parts, nano-silicon dioxide suspension dispersion: 3-5 parts, antioxidant: 2-3 parts, toughening agent: 5-8 parts, sulfur: 5-10 parts, zinc oxide: 4-8 parts, accelerator: 5-10 parts, peregal O-20: 3-6 parts; The antioxidant is prepared by the following method: S1: Pentaerythritol reacts with 3,6-dimethyl-1,4-dioxane-2,5-dione under the catalysis of stannous octoate to form a four-arm star-shaped compound; S2: The four-arm star compound reacts with 4-(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenoxy)-4-oxobutanoic acid in the presence of p-toluenesulfonic acid to form an antioxidant; The toughening agent is prepared by the following method: A1: Oleic acid reacts with formic acid and H2O2 to form epoxy compounds; A2: Epoxy compounds generate polyester compounds under the action of chromium acetylacetonate; A3: A polyester compound reacts with isophorone diisocyanate in the presence of dibutyltin dilaurate to form an isocyanate-terminated polymer. A4: The isocyanate-terminated polymer reacts with the amino-terminated silicone oil to form a toughening agent.

2. The foldable bag for an anesthesia machine according to claim 1, characterized in that: In the step S1, the mass ratio of pentaerythritol to 3,6-dimethyl-1,4-dioxane-2,5-dione is 1:(18-20).

3. The foldable bag for an anesthesia machine according to claim 1, characterized in that: In step S2, the molar ratio of the four-arm star compound to 4-(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenoxy)-4-oxobutanoic acid is 1:(2-3).

4. The foldable bag for an anesthesia machine according to claim 1, characterized in that: In step A1, the feed mass ratio of oleic acid to formic acid is 16:5; in step A2, the feed mass ratio of epoxy compound to chromium acetylacetonate is 50:1; in step A3, the feed mass ratio of polyester compound to isophorone diisocyanate is 10:1; and in step A4, the feed mass ratio of terminal isocyanate polymer to terminal amino silicone oil is 6:

1.

5. The foldable bag for an anesthesia machine according to claim 1, characterized in that: The stabilizer is a 10-25 wt% potassium hydroxide aqueous solution.

6. The foldable bag for an anesthesia machine according to claim 1, characterized in that: The accelerator is one of accelerator TMTD and accelerator BZ.

7. The foldable bag for an anesthesia machine according to claim 1, characterized in that: The mass concentration of the sodium p-styrenesulfonate aqueous solution is 25-30wt%.

8. The foldable bag for an anesthesia machine according to claim 1, characterized in that: The antioxidant, toughening agent, sulfur, zinc oxide, accelerator, and peregal O-20 are all aqueous dispersions with a total solid content of 50 wt %. The aqueous dispersions are all ground using a nano-abrasive mill until the dispersion D90 is no greater than 3 microns, and 0.6 wt % of disodium methylene dinaphthalenesulfonate is added to the ground aqueous dispersion as a surfactant.

9. An injection molding process for the folding bag for an anesthesia machine according to any one of claims 1 to 8, characterized in that: The following steps are involved: (1) Weigh by weight: natural rubber latex: 50 parts, chloroprene rubber latex: 50 parts, stabilizer: 1-3 parts, sodium p-styrene sulfonate aqueous solution: 1-2 parts, nano-silica suspension dispersion: 3-5 parts, antioxidant: 2-3 parts, toughening agent: 5-8 parts, sulfur: 5-10 parts, zinc oxide: 4-8 parts, accelerator: 5-10 parts, and peregal O-20: 3-6 parts; (2) The above raw materials were stirred and mixed, kept stirring at 45°C for 1.5 hours, and then kept at room temperature for 48 hours to obtain a matured latex; (3) Clean the mold, dry it at 80°C for 5 minutes; soak it in a 20wt% calcium nitrate aqueous solution as a coagulant, and dry it at 90°C for 5 minutes; (4) The latex was soaked and dried at 80°C for 5 minutes; the latex was leached at 60±5°C and curled; the curled latex was dried and vulcanized at 110°C for 25 minutes; the latex was demoulded, washed with hot water at 60°C, and then leached and post-processed to obtain a folding capsule for anesthesia machine.

Images