A mild and highly moisturizing amino acid facial cleanser and preparation method thereof

Abstract

Tuowei The present invention belongs to the field of cosmetic technology, and specifically relates to a mild and highly moisturizing amino acid cleanser and a preparation method thereof. The mild and highly moisturizing amino acid cleanser comprises the following raw material components in percentage by mass: 10-20% amino acid surfactant, 5-15% moisturizer, 2-6% cyclodextrin derivative, 0.5-2% pearlescent agent, 0.05-0.2% fragrance, 0.05-0.5% preservative, and the balance is water; the cyclodextrin derivative comprises one or two of hydroxypropyl cyclodextrin and fatty alcohol polyoxyethylene ether modified cyclodextrin. The present invention uses cyclodextrin derivatives in combination with polyhydroxy moisturizers to thicken and synergistically moisturize the amino acid surfactant, which can significantly improve the thickening ability, foaming performance and cleaning ability of the amino acid cleanser, and significantly improve the skin feel when used.

Description

Technical Field

[0001] The invention belongs to the technical field of cosmetics, and particularly relates to a mild and highly moisturizing amino acid facial cleanser and a preparation method thereof. Background Art

[0002] Amino acid cleansers are facial cosmetics that use amino acid surfactants as their primary cleansing ingredient. Compared to traditional soap-based cleansers, amino acid cleansers are closer to the skin's pH and less irritating, making them popular with those with sensitive or dry skin.

[0003] However, amino acid surfactants have somewhat poor cleaning performance, often requiring the addition of other surfactants to improve this, reducing mildness. They also have somewhat poor thickening properties. Conventional approaches to improve this are to use polymer thickeners, such as acrylic acid polymers, to thicken the cleanser to a paste-like consistency for easier use. However, the addition of polymer thickeners can reduce the cleanser's foaming properties, impacting the user experience.

[0004] The invention patent document with publication number CN 112957302 A records an amino acid cleanser and its preparation method, which is mainly composed of the following components and their weight fractions: 7-20 parts of amino acid surfactant, 3-13 parts of auxiliary surfactant, 2-5 parts of thickener, 4-16 parts of moisturizer, 0.5-2 parts of pearlescent agent and 38.5-80.5 parts of water. By selecting the safe and mild non-irritating potassium cocoyl glycinate as the main surfactant, supplemented by cocamidopropyl hydroxysulfobetaine and decyl glucoside, it is in the pH range suitable for human skin, gently cleans dirt and excess oil on the face, and the skin is refreshed and not tight after washing. And by adding acrylic acid (ester) copolymer and PEG-120 methyl glucose trioleate in appropriate proportions, a thickening skeleton is formed to ensure the stability of the formula, while the impact on foam performance is as small as possible, giving the formula a fine and elastic foam. However, the composition of this cleanser is relatively complex and the cost is high. Furthermore, acrylic acid (ester) copolymers still need to be used as thickeners, which has an adverse effect on foaming performance.

[0005] Therefore, providing a mild and highly moisturizing amino acid cleanser with simple ingredients, strong compatibility, low cost, and good cleaning and foaming properties has good market prospects. Summary of the Invention

[0006] The purpose of the present invention is to solve the shortcomings and deficiencies in the above-mentioned prior art and to provide a mild and highly moisturizing amino acid cleanser and a preparation method thereof.

[0007] The purpose of the present invention is achieved through the following technical solutions:

[0008] A mild and highly moisturizing amino acid facial cleanser comprises the following raw material components calculated by weight percentage:

[0009] 10-20% amino acid surfactant, 5-15% moisturizer, 2-6% cyclodextrin derivative, 0.5-2% pearlescent agent, 0.05-0.2% fragrance, 0.05-0.5% preservative, and the balance is water; the cyclodextrin derivative includes one or two of hydroxypropyl cyclodextrin and fatty alcohol polyoxyethylene ether glycidyl ether modified cyclodextrin.

[0010] Furthermore, the amino acid surfactant is one or more of cocoyl glutamate, cocoyl glycinate, lauroyl glutamate, myristoyl glutamate, and lauroyl sarcosinate.

[0011] Furthermore, the moisturizing agent is one or more of glycerin, sodium hyaluronate, propylene glycol, and butylene glycol.

[0012] Furthermore, the hydroxypropyl cyclodextrin is a condensation product of cyclodextrin and propylene oxide, which can be purchased from the market.

[0013] Furthermore, the fatty alcohol polyoxyethylene ether glycidyl ether modified cyclodextrin is a condensation product of cyclodextrin and fatty alcohol polyoxyethylene ether glycidyl ether, which is prepared by the following method:

[0014] Add cyclodextrin to an alkaline aqueous solution, heat to 40-60°C, stir and dissolve, then add dropwise an aqueous solution of fatty alcohol polyoxyethylene ether glycidyl ether and keep warm for reaction. After the reaction is completed, add acid for neutralization, concentrate under reduced pressure, add ethanol for precipitation and desalination, and vacuum spray dry to obtain fatty alcohol polyoxyethylene ether glycidyl ether modified cyclodextrin.

[0015] Furthermore, the cyclodextrin is β-cyclodextrin; and the alkaline aqueous solution is a sodium hydroxide solution with a mass fraction of 5 to 30%.

[0016] Furthermore, the molecular formula of the fatty alcohol polyoxyethylene ether glycidyl ether is C m H 2m+1 O(CH2CH2O) n CH2CH(O)CH2, m is an integer of 12 to 18, and n is an integer of 6 to 18. It can be obtained by conventional end-capping reaction of fatty alcohol polyoxyethylene ether (AEO) and epichlorohydrin.

[0017] Furthermore, the added amount of the fatty alcohol polyoxyethylene ether glycidyl ether is 50-200% of the mass of the cyclodextrin, and the substitution degree of the obtained fatty alcohol polyoxyethylene ether glycidyl ether modified cyclodextrin is 0.25-1.15.

[0018] Furthermore, the insulation reaction time is 2 to 6 hours.

[0019] The preparation method of the mild and highly moisturizing amino acid facial cleanser comprises the following steps:

[0020] Amino acid surfactant, moisturizer and cyclodextrin derivative are added to water, heated at 60-80°C and stirred to mix evenly, then pearlescent agent, fragrance and preservative are added and emulsified to a uniform phase, and cooled to room temperature to obtain a mild and highly moisturizing amino acid cleanser.

[0021] Compared with the prior art, the present invention has the following beneficial effects:

[0022] (1) The present invention uses cyclodextrin derivatives in combination with polyhydroxy moisturizers to perform hydrogen bond thickening and hydrophobic thickening on amino acid surfactants. Compared with conventional acrylic polymer thickeners, the present invention can reduce the adverse effects on the foaming performance of amino acid cleansers and improve the user experience.

[0023] (2) The present invention uses cyclodextrin derivatives in conjunction with moisturizers to further improve the moisturizing effect, reduce skin tightness after cleansing, and improve skin feel.

[0024] (3) The present invention further uses fatty alcohol polyoxyethylene ether glycidyl ether modified cyclodextrin as a thickener and synergistic moisturizer, which can further improve the foaming performance and cleaning ability of the amino acid cleanser while having good thickening performance and synergistic moisturizing effect. DETAILED DESCRIPTION

[0025] In order to make the purpose, technical solutions and advantages of the present invention clearer, the technical solutions of the present invention will be described in detail below, but this is not a limitation of the present invention. Example 1

[0026] A mild and highly moisturizing amino acid facial cleanser, the raw material composition ratio of which is as follows:

[0027] Sodium cocoyl glutamate 16%, glycerin 6%, butylene glycol 4%, sodium hyaluronate 1%, hydroxypropyl cyclodextrin (commercially available, condensation product of β-cyclodextrin and propylene oxide) 4%, pearlizing agent ethylene glycol stearate 1%, fragrance 0.1%, preservative phenoxyethanol 0.1%, the balance is water.

[0028] The preparation method of the mild and highly moisturizing amino acid cleanser is as follows:

[0029] Add sodium cocoyl glutamate, glycerin, butylene glycol, sodium hyaluronate and hydroxypropyl cyclodextrin into an emulsifying pot with hot water at 60-80°C and stir to mix evenly. Then add pearlescent agent ethylene glycol stearate, fragrance and preservative phenoxyethanol and emulsify to a uniform phase. After cooling to room temperature, a mild and highly moisturizing amino acid cleanser is obtained.

[0030] The amino acid facial cleanser obtained in this example is a milky white, pearlescent, viscous emulsion with a pH of 6.2 (measured using a pH meter) and a viscosity of 25,640 mPa·s (measured using a rotor viscometer). Foaming performance was tested using a waring-blender method: a sample of the resulting facial cleanser was diluted 50-fold with deionized water and added to a measuring cup. Stirring was continued at a constant speed for 60 seconds, then the volume of the foam produced was recorded. The initial foam volume was 136 ml, and the foam volume after 10 minutes was 115 ml. Example 2

[0031] A mild and highly moisturizing amino acid facial cleanser, the raw material composition ratio of which is as follows:

[0032] Sodium cocoyl glutamate 10%, glycerin 3%, butylene glycol 2%, sodium hyaluronate 0.5%, hydroxypropyl cyclodextrin 6%, pearlizing agent ethylene glycol stearate 0.5%, fragrance 0.05%, preservative phenoxyethanol 0.2%, the balance is water.

[0033] The preparation method of the mild and highly moisturizing amino acid cleanser is the same as that in Example 1.

[0034] The amino acid facial cleanser obtained in this example is a milky white pearlescent viscous emulsion with a pH of 6.5 and a viscosity of 32520 mPa·s. The foaming performance test shows that the initial foam volume is 105 ml and the foam volume after 10 minutes is 90 ml. Example 3

[0035] A mild and highly moisturizing amino acid facial cleanser, the raw material composition ratio of which is as follows:

[0036] Sodium cocoyl glutamate 12%, glycerin 4%, butylene glycol 3%, sodium hyaluronate 0.5%, hydroxypropyl cyclodextrin 5%, pearlizing agent ethylene glycol stearate 0.5%, fragrance 0.05%, preservative phenoxyethanol 0.15%, the balance is water.

[0037] The preparation method of the mild and highly moisturizing amino acid cleanser is the same as that in Example 1.

[0038] The amino acid facial cleanser obtained in this example is a milky white pearlescent viscous emulsion with a pH of 6.4 and a viscosity of 29600 mPa·s. The foaming performance test shows that the initial foam volume is 120 ml and the foam volume after 10 minutes is 103 ml. Example 4

[0039] A mild and highly moisturizing amino acid facial cleanser, the raw material composition ratio of which is as follows:

[0040] Sodium cocoyl glycinate 14%, glycerin 5%, butylene glycol 3%, sodium hyaluronate 1%, hydroxypropyl cyclodextrin 4%, pearlizing agent ethylene glycol stearate 1.5%, fragrance 0.1%, preservative phenoxyethanol 0.1%, the balance is water.

[0041] The preparation method of the mild and highly moisturizing amino acid cleanser is the same as that in Example 1.

[0042] The amino acid facial cleanser obtained in this example is a milky white pearlescent viscous emulsion with a pH of 6.3 and a viscosity of 27880 mPa·s. The foaming performance test shows that the initial foam volume is 126 ml and the foam volume after 10 minutes is 102 ml. Example 5

[0043] A mild and highly moisturizing amino acid facial cleanser, the raw material composition ratio of which is as follows:

[0044] Sodium lauroyl glutamate 16%, glycerin 5%, propylene glycol 4%, sodium hyaluronate 1%, hydroxypropyl cyclodextrin 4%, pearlescent agent ethylene glycol stearate 1.5%, fragrance 0.1%, preservative phenoxyethanol 0.1%, the balance is water.

[0045] The preparation method of the mild and highly moisturizing amino acid cleanser is the same as that in Example 1.

[0046] The amino acid facial cleanser obtained in this example is a milky white pearlescent viscous emulsion with a pH of 6.2 and a viscosity of 28520 mPa·s. The foaming performance test shows that the initial foam volume is 148 ml and the foam volume after 10 minutes is 128 ml. Example 6

[0047] A mild and highly moisturizing amino acid facial cleanser, the raw material composition ratio of which is as follows:

[0048] Sodium lauroyl sarcosinate 18%, glycerin 6%, propylene glycol 5%, sodium hyaluronate 1%, hydroxypropyl cyclodextrin 3%, pearlizing agent ethylene glycol stearate 1.5%, fragrance 0.1%, preservative phenoxyethanol 0.1%, the balance is water.

[0049] The preparation method of the mild and highly moisturizing amino acid cleanser is the same as that in Example 1.

[0050] The amino acid facial cleanser obtained in this example is a milky white pearlescent viscous emulsion with a pH of 6.2 and a viscosity of 25280 mPa·s. The foaming performance test shows that the initial foam volume is 160 ml and the foam volume after 10 minutes is 135 ml. Example 7

[0051] A mild and highly moisturizing amino acid facial cleanser, the raw material composition ratio of which is as follows:

[0052] Sodium myristoyl glutamate 20%, glycerin 8%, butylene glycol 4%, sodium hyaluronate 2%, hydroxypropyl cyclodextrin 2%, pearlescent agent ethylene glycol stearate 2%, fragrance 0.2%, preservative phenoxyethanol 0.05%, the balance is water.

[0053] The preparation method of the mild and highly moisturizing amino acid cleanser is the same as that in Example 1.

[0054] The amino acid facial cleanser obtained in this example is a milky white pearlescent viscous emulsion with a pH of 6.3 and a viscosity of 22160 mPa·s. The foaming performance test shows that the initial foam volume is 152 ml and the foam volume after 10 minutes is 132 ml. Example 8

[0055] A mild and highly moisturizing amino acid facial cleanser is disclosed. Compared with Example 1, fatty alcohol polyoxyethylene ether glycidyl ether modified cyclodextrin is used instead of hydroxypropyl cyclodextrin, and the rest of the ingredients are the same.

[0056] The fatty alcohol polyoxyethylene ether glycidyl ether modified cyclodextrin is prepared by the following method:

[0057] Add β-cyclodextrin to a 20% sodium hydroxide solution and heat to 50-55°C, stirring to dissolve, and then dropwise add fatty alcohol polyoxyethylene ether glycidyl ether (AEO-9 (RO-(CH2CH2O) n H, R=C12, n=9) and an aqueous solution of a blocked product of epichlorohydrin) were incubated for 4 hours, the mass ratio of the added amount of fatty alcohol polyoxyethylene ether glycidyl ether to β-cyclodextrin was 1:1, and the degree of substitution of cyclodextrin was 0.52 as measured by titration. After the reaction was completed, hydrochloric acid was added to neutralize the mixture to a pH of 7, and the mixture was concentrated under reduced pressure to about 1 / 2 volume. Then, 2 volumes of anhydrous ethanol were added for precipitation, and the mixture was filtered to remove salt. The filtrate was vacuum spray dried to obtain fatty alcohol polyoxyethylene ether glycidyl ether modified cyclodextrin.

[0058] The amino acid facial cleanser obtained in this example is a milky white pearlescent viscous emulsion with a pH of 6.6 and a viscosity of 23820 mPa·s. The foaming performance test shows that the initial foam volume is 208 ml and the foam volume after 10 minutes is 180 ml.

[0059] By comparing the results of this embodiment with those of Example 1, it can be seen that the foaming performance of the obtained amino acid cleanser can be further significantly improved by using fatty alcohol polyoxyethylene ether glycidyl ether to modify cyclodextrin compared with hydroxypropyl cyclodextrin.

[0060] Comparative Example 1

[0061] An amino acid facial cleanser is described. Compared with Example 1, hydroxypropyl cyclodextrin is not added, and the other aspects are the same.

[0062] The amino acid facial cleanser obtained in this comparative example is a milky white pearlescent emulsion with a pH value of 6.3 and a viscosity of 9640 mPa·s. The foaming performance test shows that the initial foam volume is 145 ml and the foam volume after 10 minutes is 110 ml.

[0063] By comparing the results of this comparative example with those of Examples 1 and 8, it can be seen that the viscosity of the amino acid cleanser can be significantly increased by adding a cyclodextrin derivative in the present invention without significantly adversely affecting the foaming performance.

[0064] Comparative Example 2

[0065] An amino acid facial cleanser is disclosed. Compared with Example 1, 0.45% of a carbomer thickener is used to replace hydroxypropyl cyclodextrin, and the rest of the ingredients are the same.

[0066] The amino acid facial cleanser obtained in this comparative example is a milky white pearlescent viscous emulsion with a pH of 6.1 and a viscosity of 26200 mPa·s. The foaming performance test shows that the initial foam volume is 75 ml and the foam volume after 10 minutes is 52 ml.

[0067] By comparing the results of this comparative example with Example 1 and Comparative Example 1, it can be seen that the use of conventional acrylic polymer thickeners has a significant adverse effect on the foaming performance of the amino acid facial cleanser.

[0068] Comparative Example 3

[0069] An amino acid facial cleanser, compared with Example 1, uses an equal amount of β-cyclodextrin instead of hydroxypropyl cyclodextrin.

[0070] The amino acid facial cleanser obtained in this comparative example is a milky white pearlescent viscous emulsion with a pH of 6.3 and a viscosity of 14860 mPa·s. The foaming performance test shows that the initial foam volume is 116 ml and the foam volume after 10 minutes is 90 ml.

[0071] Comparison of this comparative example with Example 1 and Comparative Example 1 reveals that the use of unmodified cyclodextrin has a certain adverse effect on the foaming performance of the amino acid facial cleanser, and its thickening performance is significantly reduced. This is due to the poor water solubility of unmodified cyclodextrin, which reduces its hydrogen bonding and hydrophobic association with the polyhydroxy moisturizer and amino acid surfactant.

[0072] Comparative Example 4

[0073] An amino acid facial cleanser, compared with Example 8, uses 2% β-cyclodextrin and 2% fatty alcohol polyoxyethylene ether (AEO-9) to replace the fatty alcohol polyoxyethylene ether glycidyl ether modified cyclodextrin.

[0074] The amino acid facial cleanser obtained in this comparative example is a milky white pearlescent viscous emulsion with a pH of 6.3 and a viscosity of 15400 mPa·s. The foaming performance test shows that the initial foam volume is 166 ml and the foam volume after 10 minutes is 125 ml.

[0075] Comparison of this comparative example with Examples 1 and 8 shows that the foaming performance of the amino acid cleanser can be improved by compounding with an AEO surfactant, but the improvement is not as good as that achieved with the fatty alcohol polyoxyethylene ether glycidyl ether-modified cyclodextrin in Example 8. Furthermore, compounding with an AEO surfactant does not significantly improve the thickening performance.

[0076] The moisturizing and cleansing effects of the amino acid cleansing milks obtained in Examples 1 and 8 and Comparative Examples 1 to 4 were evaluated. Sixty volunteers aged 20 to 45 were randomly divided into six groups of 10 each. The volunteers were given the above-mentioned test samples and their moisturizing and cleansing effects after cleansing were evaluated. The moisturizing effect was scored based on whether the face was moisturized without feeling dry or tight, with a score of 0 to 5, with a higher score for a better feeling. The average value was recorded. The cleansing effect was scored based on whether the face felt refreshed and non-greasy, with a score of 0 to 5, with a higher score for a better feeling. The average value was recorded. The evaluation results are shown in Table 1 below.

[0077] Table 1

[0078] Test samples Moisturizing effect Cleaning effect Example 1 4.4 4.1 Example 8 4.5 4.8 Comparative Example 1 3.6 4.2 Comparative Example 2 3.5 4.0 Comparative Example 3 3.8 3.9 Comparative Example 4 3.0 4.8

[0079] Comparisons of Examples 1 and 8 with Comparative Examples 1-3 in Table 1 demonstrate that the specific cyclodextrin derivatives employed in the present invention can synergize with the moisturizer component to achieve enhanced moisturizing effects. Comparisons of Example 8 with Example 1 demonstrate that the use of cyclodextrin modified with fatty alcohol polyoxyethylene ether glycidyl ether further enhances the cleansing ability of the amino acid cleanser compared to hydroxypropyl cyclodextrin, while also providing superior mildness. Comparative Example 4 demonstrates that the use of an AEO surfactant blend achieves superior cleansing effects, but can lead to a dry, tight sensation on the face after cleansing, reducing mildness and moisturizing effects.

[0080] The above embodiments are preferred implementations of the present invention, but the implementations of the present invention are not limited to the above embodiments. Any other changes, modifications, substitutions, combinations, and simplifications that do not deviate from the spirit and principles of the present invention should be considered as equivalent replacement methods and are included in the scope of protection of the present invention.

Claims

1. A mild and highly moisturizing amino acid cleanser, characterized in that: The raw material components are as follows: Amino acid surfactant 10-20%, moisturizer 5-15%, fatty alcohol polyoxyethylene ether glycidyl ether modified cyclodextrin 2-6%, pearlizing agent 0.5-2%, flavor 0.05-0.2%, preservative 0.05-0.5%, balance water; The moisturizing agent is one or more of glycerin, sodium hyaluronate, propylene glycol, and butylene glycol; The fatty alcohol polyoxyethylene ether glycidyl ether modified cyclodextrin is prepared by the following method: Add cyclodextrin to an alkaline aqueous solution, heat to 40-60°C, stir and dissolve, then dropwise add an aqueous solution of fatty alcohol polyoxyethylene ether glycidyl ether and keep warm for reaction. After the reaction is completed, add acid for neutralization, concentrate under reduced pressure, add ethanol for precipitation and desalination, and vacuum spray dry to obtain fatty alcohol polyoxyethylene ether glycidyl ether modified cyclodextrin; The cyclodextrin is β-cyclodextrin; the molecular formula of the fatty alcohol polyoxyethylene ether glycidyl ether is C m H 2m+1 O(CH2CH2O) n CH2CH(O)CH2, m is an integer from 12 to 18, and n is an integer from 6 to 18; The substitution degree of the obtained fatty alcohol polyoxyethylene ether glycidyl ether modified cyclodextrin is 0.25-1.

15.

2. A mild and highly moisturizing amino acid cleanser according to claim 1, characterized in that: The amino acid surfactant is one or more of cocoyl glutamate, cocoyl glycinate, lauroyl glutamate, myristoyl glutamate, and lauroyl sarcosinate.

3. A mild and highly moisturizing amino acid facial cleanser according to claim 1, characterized in that: The alkaline aqueous solution is a sodium hydroxide solution with a mass fraction of 5 to 30%.

4. A mild and highly moisturizing amino acid facial cleanser according to claim 1, characterized in that: The added amount of the fatty alcohol polyoxyethylene ether glycidyl ether is 50-200% of the mass of the cyclodextrin.

5. The mild and highly moisturizing amino acid facial cleanser according to claim 1, characterized in that: The insulation reaction time is 2 to 6 hours.

6. The method for preparing a mild and highly moisturizing amino acid facial cleanser according to any one of claims 1 to 5, characterized in that: The method comprises the following preparation steps: Amino acid surfactant, moisturizer and fatty alcohol polyoxyethylene ether glycidyl ether modified cyclodextrin are added to water, heated at 60-80°C and stirred to mix evenly, then pearlescent agent, fragrance and preservative are added and emulsified to a uniform phase, and cooled to room temperature to obtain a mild and highly moisturizing amino acid cleanser.