Composition, preparation method thereof and application of composition in preparation of poultry feed additive

Abstract

The invention relates to the technical field of traditional Chinese medicines, in particular to a composition, a preparation method thereof and application of the composition in preparation of a poultry feed additive. The four raw materials of herba houttuyniae, radix isatidis, pericarpium trichosanthis and anisodus tanguticus slag powder are selected, through reasonable composition and scientific compatibility, all the components show a synergistic effect in the aspects of increasing the growth rate of broiler chickens and improving the growth performance, and the feed additive is safe and free of toxic and side effects, so that the feed additive can be used as a poultry feed additive for poultry breeding, and the feed additive has good economic benefits. The basic requirements of modern agricultural ecological safe breeding and sustainable development are met.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicines, and particularly relates to a composition, a preparation method thereof, and an application thereof in the preparation of poultry feed additives. Background Art

[0002] Anisodus tanguticus is a common medicinal plant in plateau areas. Its main active ingredients are tropane alkaloids, and these ingredients are used in medicine for spasmolysis, analgesia, and improving microcirculation. Although Anisodus tanguticus has the effect of increasing the fattening of livestock, it also contains highly toxic substances. In the pharmaceutical process, the active ingredients are usually extracted from Anisodus tanguticus, but the medicinal residues generated in the extraction process are mostly regarded as waste and directly discarded, which not only wastes resources but also increases the treatment cost.

[0003] Traditional poultry feeds are mainly composed of raw materials such as grains and soybean meal. Although they can provide basic nutrition, they are insufficient in the comprehensiveness and balance of nutritional components. For example, the contents of some essential amino acids, vitamins, and minerals and other nutritional elements may not meet the needs of poultry at different growth stages and production performances, thus affecting the growth rate, immunity, and egg-laying performance of poultry. In the past poultry farming, in order to prevent and treat diseases and promote growth, antibiotics were widely added to feeds. However, the long-term abuse of antibiotics has led to many problems, such as the generation of drug-resistant strains of pathogenic bacteria, which reduces the therapeutic effect of antibiotics; drug residues in poultry products pose a potential threat to human health, such as causing allergic reactions and drug resistance transmission; at the same time, it will also disrupt the microecological balance in the poultry intestine and affect its normal digestion and immune functions. Summary of the Invention

[0004] In view of this, the technical problem to be solved by the present invention is to provide a composition, a preparation method thereof, and an application thereof in the preparation of poultry feed additives. The feed additive provided by the present invention uses the treated medicinal residues to be converted into feed additives, which can not only effectively utilize waste but also improve the weight gain rate of poultry, reduce the incidence rate and mortality rate.

[0005] The present invention provides a composition, which is composed of the following raw materials in parts by weight:

[0006] 2 - 5 parts of Houttuynia cordata, 2 - 5 parts of Isatis indigotica, 2 - 5 parts of Trichosanthes kirilowii peel, and 8 - 15 parts of Anisodus tanguticus residue powder.

[0007] Houttuynia cordata is the fresh whole herb or the dried aerial part of Houttuynia cordata Thunb., which belongs to the genus Houttuynia in the Saururaceae family. It is mainly distributed in the provinces along and south of the Yangtze River. Visually, the stem is flattened and cylindrical, twisted, with a brownish-yellow surface, several longitudinal ridges, obvious nodes, and remaining fibrous roots at the lower nodes; it is brittle and easy to break. It has a pungent taste and a slightly cold nature. In traditional medicine, it has the effects of clearing heat and detoxifying, eliminating carbuncles and discharging pus, and promoting diuresis and relieving stranguria. In pharmacological research, Houttuynia cordata has various effects such as antibacterial, antiviral, and anti-inflammatory effects. For example, it has a certain inhibitory effect on Staphylococcus aureus, influenza virus, etc.

[0008] Isatis root is the dried root of Isatis indigotica Fort., which belongs to the genus Isatis in the Brassicaceae family. It is cultivated throughout China. Its root is cylindrical, slightly twisted, with a pale grayish-yellow or pale brownish-yellow surface, longitudinal wrinkles, transverse lenticel-like protrusions, and branch root scars. It is cold in nature and bitter in taste. It has the effects of clearing heat and detoxifying, cooling blood and relieving sore throat. Modern research has found that Isatis root contains various chemical components such as indigo and indirubin, and has pharmacological activities such as antibacterial, antiviral, and anti-endotoxin, and has preventive and therapeutic effects on some diseases caused by virus infections.

[0009] Trichosanthes peel is the dried mature pericarp of Trichosanthes kirilowii Maxim. or Trichosanthes rosthornii Harms, which belongs to the genus Trichosanthes in the Cucurbitaceae family. It is mainly produced in Shandong, Hebei, Shanxi, Shaanxi and other places. It is shell-shaped, brittle and easy to break, with an orange-red or orange-yellow outer surface, wrinkled, and a yellowish-white inner surface. It tastes sweet, slightly bitter, and is cold in nature. It has the effects of clearing heat and resolving phlegm, promoting qi and widening the chest. Pharmacologically, Trichosanthes peel has a certain effect on the cardiovascular system. For example, it can dilate the coronary artery and resist myocardial ischemia, and at the same time has a certain expectorant effect.

[0010] Anisodus tanguticus (Maxim.) Pascher is a plant of the genus Anisodus in the Solanaceae family. Anisodus tanguticus residue powder is made from the residue remaining after the extraction and other processing of Anisodus tanguticus. Anisodus tanguticus has the effects of analgesia and spasmolysis, promoting blood circulation to remove stasis, stopping bleeding and promoting granulation. Anisodus tanguticus residue powder may retain some active ingredients or other ingredients to a certain extent.

[0011] In the present invention, four raw materials, namely Houttuynia cordata, Isatis root, Trichosanthes peel, and Anisodus tanguticus residue powder, are selected. Through reasonable formulation and scientific compatibility, each component shows a synergistic effect in improving the growth rate of broilers and improving growth performance, and is safe and non-toxic. Therefore, it can be used as a poultry feed additive for poultry breeding, meeting the basic requirements of modern agricultural ecological safety breeding and sustainable development.

[0012] In some embodiments, it is composed of the following raw materials in parts by weight:

[0013] 5 parts of Houttuynia cordata, 5 parts of Isatis root, 5 parts of Trichosanthes peel, and 15 parts of Anisodus tanguticus residue powder

[0014] The present invention provides a preparation method of the said composition, which includes obtaining the composition by mixing, pulverizing, and sieving Houttuynia cordata, Isatis root, Trichosanthes peel, and Anisodus tanguticus residue powder.

[0015] The present invention provides the use of the described composition or the composition prepared by the described preparation method in the preparation of poultry feed additives.

[0016] In some embodiments, the poultry includes at least one of chickens, ducks and geese.

[0017] In some specific embodiments, the poultry is a chicken.

[0018] The present invention provides a poultry feed additive, including the described composition or the composition prepared by the described preparation method.

[0019] The present invention provides a feed, including the described poultry feed additive and a basic feed.

[0020] In some embodiments, the mass ratio of the poultry feed additive to the basic feed is (0.1 - 0.2):1.

[0021] In some specific embodiments, the mass ratio of the poultry feed additive to the basic feed is 0.127:1.

[0022] In some embodiments, the basic feed is composed of the following raw materials in parts by weight:

[0023] Fish meal 10 - 20 parts, soybean meal 40 - 60 parts, wheat bran 2 - 5 parts, corn flour 120 - 180 parts, stone powder 1 - 3 parts, rapeseed meal 5 - 15 parts, additive 0.5 - 3 parts, and calcium hydrogen phosphate 1 - 3 parts. The additive is composed of oxytetracycline, furazolidone and ethylparaben in a mass ratio of 2:2:1.

[0024] In some specific embodiments, the basic feed is composed of the following raw materials in parts by weight:

[0025] Fish meal 15 parts, soybean meal 50 parts, wheat bran 5 parts, corn flour 150 parts, stone powder 2 parts, rapeseed meal 12 parts, additive 1 part, and calcium hydrogen phosphate 1 part.

[0026] Compared with the prior art, the beneficial effects of the present invention include:

[0027] 1. Resource recycling: This technical solution directly uses the scopolia residue as a raw material for livestock feed, realizing waste recycling, reducing resource waste, and at the same time reducing the treatment cost;

[0028] 2. Environmental protection: Compared with the existing treatment methods, it reduces environmental pollution, is more environmentally friendly, and meets the basic requirements of modern agricultural ecological safety breeding and sustainable development;

[0029] 3. High economic benefits: This technical solution converts the scopolia residue into valuable feed raw materials, improving the utilization rate of resources and having high economic benefits;

[0030] 4. Improve feed quality: In the present invention, four raw materials, namely, Houttuynia cordata, Isatis indigotica, Trichosanthes kirilowii peel, and Anisodus tanguticus residue powder, are selected. Through reasonable formulation and scientific compatibility, each component shows a synergistic effect in improving the growth rate of broilers and enhancing growth performance, which can improve the nutritional value of feed, strengthen the physique of animals, improve breeding efficiency, and has no safety toxic and side effects. Therefore, it can be used as a poultry feed additive for poultry breeding;

[0031] 5. Simple operation and easy to implement: The treatment method of this technical solution is simple and easy to perform, without complex equipment and operations, and is easy to promote and apply in the breeding industry. Detailed implementation manners

[0032] The present invention provides a composition, a preparation method thereof, and an application thereof in the preparation of a poultry feed additive. Those skilled in the art can draw on the content of this article and appropriately improve the process parameters to achieve it. It should be particularly noted that all similar substitutions and modifications are obvious to those skilled in the art, and they are all considered to be included in the present invention. The methods and applications of the present invention have been described through preferred embodiments. Relevant personnel can obviously make changes or appropriate alterations and combinations to the methods and applications in this article without departing from the content, spirit, and scope of the present invention to implement and apply the technology of the present invention.

[0033] The test materials used in the present invention are all ordinary commercially available products and can be purchased in the market. The present invention will be further described below in conjunction with embodiments.

[0034] Example 1

[0035] A method for preparing chicken feed using Anisodus tanguticus residue as a raw material includes the following steps:

[0036] 1. Feed preparation process

[0037] 1.1. Treatment of Anisodus tanguticus residue:

[0038] The Anisodus tanguticus residue comes from Chengdu No. 1 Pharmaceutical Raw Material Co., Ltd., batch number 240501. The general production process of the Anisodus tanguticus residue is that Anisodus tanguticus is crushed and extracted, and then the extraction solvent is volatilized by steam. The treated residue basically does not contain tropane alkaloids and can be used for livestock feed.

[0039] The residue is dried (sun-dried or dried in an oven, and the drying temperature does not exceed 80 °C), crushed and sieved (particle size 0.1 - 2 mm) to obtain Anisodus tanguticus residue powder.

[0040] 1.2. Preparation of other auxiliary medicinal powders:

[0041] Weigh dry Houttuynia cordata, Isatis indigotica, and Trichosanthes kirilowii peel, crush and sieve (particle size 0.1 - 2 mm)

[0042] 1.3. Grouping

[0043] Ingredient list of Group 1: 5 parts by weight of Houttuynia cordata, 5 parts by weight of Isatis tinctoria, 5 parts by weight of Trichosanthes kirilowii Maxim. peel, 15 parts by weight of anisodus acutangulus residue powder, 15 parts by weight of fish meal, 50 parts by weight of soybean meal, 5 parts by weight of wheat bran, 150 parts by weight of corn flour, 2 parts by weight of stone powder, 12 parts by weight of rapeseed meal, 1 part by weight of additive, 1 part by weight of calcium hydrogen phosphate.

[0044] Ingredient list of Group 2: 15 parts by weight of fish meal, 50 parts by weight of soybean meal, 5 parts by weight of wheat bran, 150 parts by weight of corn flour, 2 parts by weight of stone powder, 12 parts by weight of rapeseed meal, 1 part by weight of additive, 1 part by weight of calcium hydrogen phosphate.

[0045] Ingredient list of Group 3: 5 parts by weight of Houttuynia cordata, 5 parts by weight of Isatis tinctoria, 5 parts by weight of Trichosanthes kirilowii Maxim. peel, 15 parts by weight of fish meal, 50 parts by weight of soybean meal, 5 parts by weight of wheat bran, 150 parts by weight of corn flour, 2 parts by weight of stone powder, 12 parts by weight of rapeseed meal, 1 part by weight of additive, 1 part by weight of calcium hydrogen phosphate.

[0046] Ingredient list of Group 4: 5 parts by weight of Houttuynia cordata, 5 parts by weight of Isatis tinctoria, 5 parts by weight of Trichosanthes kirilowii Maxim. peel, 10 parts by weight of anisodus acutangulus residue powder, 15 parts by weight of fish meal, 50 parts by weight of soybean meal, 5 parts by weight of wheat bran, 150 parts by weight of corn flour, 2 parts by weight of stone powder, 12 parts by weight of rapeseed meal, 1 part by weight of additive, 1 part by weight of calcium hydrogen phosphate.

[0047] Ingredient list of Group 5: Only contains anisodus acutangulus residue powder.

[0048] Ingredient list of Group 6: 2 parts by weight of Houttuynia cordata, 2 parts by weight of Isatis tinctoria, 2 parts by weight of Trichosanthes kirilowii Maxim. peel, 8 parts by weight of anisodus acutangulus residue powder, 15 parts by weight of fish meal, 50 parts by weight of soybean meal, 5 parts by weight of wheat bran, 150 parts by weight of corn flour, 2 parts by weight of stone powder, 12 parts by weight of rapeseed meal, 1 part by weight of additive, 1 part by weight of calcium hydrogen phosphate.

[0049] Ingredient list of Group 7: 15 parts by weight of anisodus acutangulus residue powder, 15 parts by weight of fish meal, 50 parts by weight of soybean meal, 5 parts by weight of wheat bran, 150 parts by weight of corn flour, 2 parts by weight of stone powder, 12 parts by weight of rapeseed meal, 1 part by weight of additive, 1 part by weight of calcium hydrogen phosphate.

[0050] In the above grouping, the additive includes oxytetracycline, furazolidone and ethylparaben, and the ratio is 2:2:1.

[0051] Take the above grouping and mix evenly. After mixing, crush and sieve (particle size 0.1 - 2 mm).

[0052] 1.4. Packaging

[0053] Pack with PE bags or other suitable packaging materials.

[0054] 2. Feed effect experiment

[0055] Rearing environment: All chickens are reared under the same temperature, humidity, and lighting conditions.

[0056] Feed supply: Feed and water are supplied at regular times every day to ensure that each chicken can feed freely.

[0057] Health monitoring: Observe the health of the chickens every day

[0058] Experimental period: 30 days

[0059] Data recording: Record the weight and feed consumption of each chicken every 5 days.

[0060] 3. Experimental results

[0061] Table 1

[0062]

[0063] The experimental results in Table 1 show that adding scopolia residue to the conventional chicken feed formula can significantly improve the average weight gain rate of broilers. Adding trichosanthes peel and isatis root can significantly reduce the incidence and mortality rate. Moreover, the mental state is very good during the feeding process and after the experiment, and they like to eat the feed of the present invention.

[0064] The above is only the preferred embodiment of the present invention. It should be noted that for those of ordinary skill in the art, without departing from the principle of the present invention, several improvements and refinements can be made, and these improvements and refinements should also be regarded as the protection scope of the present invention.

Claims

1. A composition, characterized in that, It consists of the following raw materials in parts by weight: 2 - 5 parts of Houttuynia cordata, 2 - 5 parts of Isatis indigotica, 2 - 5 parts of Trichosanthes kirilowii peel, and 8 - 15 parts of anisodus acutangulus residue powder.

2. The composition according to claim 1, wherein It consists of the following raw materials in parts by weight: 5 parts of Houttuynia cordata, 5 parts of Isatis indigotica, 5 parts of Trichosanthes kirilowii peel, and 15 parts of anisodus acutangulus residue powder.

3. A method for preparing the composition according to claim 1 or 2, characterized in that, It includes obtaining the composition by mixing, pulverizing, and sieving Houttuynia cordata, Isatis indigotica, Trichosanthes kirilowii peel, and anisodus acutangulus residue powder.

4. Use of the composition according to claim 1 or 2 or the composition prepared by the preparation method according to claim 3 in the preparation of poultry feed additives.

5. The application according to claim 4, characterized in that, The poultry includes at least one of chickens, ducks, and geese.

6. Poultry feed additive, characterized in that, It includes the composition according to claim 1 or 2 or the composition prepared by the preparation method according to claim 3.

7. Feed, characterized in that, It includes the poultry feed additive according to claim 6 and a basic feed.

8. The feed according to claim 7, characterized in that, The mass ratio of the poultry feed additive to the basic feed is (0.1 - 0.2):

1.

9. The feed according to claim 7 or 8, characterized in that, The basic feed consists of the following raw materials in parts by weight: 10 - 20 parts of fish meal, 40 - 60 parts of soybean meal, 2 - 5 parts of wheat bran, 120 - 180 parts of corn flour, 1 - 3 parts of limestone powder, 5 - 15 parts of rapeseed meal, 0.5 - 3 parts of additive, and 1 - 3 parts of calcium hydrogen phosphate, and the additive consists of oxytetracycline, furazolidone, and ethylparaben in a mass ratio of 2:2:

1.

10. The feed according to any one of claims 7 to 9, characterized in that, The basic feed consists of the following raw materials in parts by weight: 15 parts of fish meal, 50 parts of soybean meal, 5 parts of wheat bran, 150 parts of corn flour, 2 parts of limestone powder, 12 parts of rapeseed meal, 1 part of additive, and 1 part of calcium hydrogen phosphate.

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