Oil-controlling and acne-removing composition specially researched for teenagers and application of oil-controlling and acne-removing composition

Abstract

The invention relates to the technical field of cosmetics, in particular to an oil-controlling and acne-removing composition specially researched for teenagers and application of the oil-controlling and acne-removing composition. The fig fruit extract in the composition has oil-controlling, soothing and anti-inflammatory effects, the European fairweed bud extract can effectively reduce sebum secretion and inhibit expression of inflammatory factors, and the ganoderma lucidum extract is rich in triterpenoids and polysaccharide compounds and can effectively regulate skin health and enhance the barrier function of the skin, so that the skin can be effectively nourished, and the skin can be effectively nourished. The three substances are combined for use, so that the obvious oil-controlling and acne-removing effects are achieved.

Description

Technical Field

[0001] The present invention relates to the technical field of cosmetics, and specifically relates to an oil-control and acne-removing composition, a composition for specifically researching and developing oil-control and acne-removing for teenagers and its application. Background Art

[0002] Due to factors such as fluctuations in multiple hormone levels in the body, hyperfunction of sebaceous glands, and abnormal follicular keratinization in the adolescent group, they often face problems such as frequent acne, enlarged pores, and oily skin. Traditional oil-control and acne-removing products mostly use a single active ingredient (such as salicylic acid, benzoyl peroxide, or antibiotics) to specifically solve a certain link (such as exfoliating cutin, killing Propionibacterium acnes, or inhibiting inflammation), but there are three core defects: First, excessive attention is paid to the regulation of sebum secretion while ignoring the balance of skin microecology, resulting in the growth of drug-resistant strains of Propionibacterium acnes and the disorder of skin flora diversity; Second, simply relying on exfoliating components is likely to damage the natural barrier function of the skin, exacerbating the risk of transdermal water loss and sensitivity; Third, long-term use of chemically synthesized components may cause skin irritation or systemic side effects, especially the safety of the adolescent group in the stage of skin barrier development during puberty is questionable. Research shows that the occurrence of acne is not only a problem of local microbial infection, but also a complex pathological process intertwined with multiple factors such as metabolic disorders of the pilosebaceous unit, immune microenvironment disorders, and damage to the physical barrier. Recent research has pointed out that mechanisms such as excessive proliferation of follicular duct epithelial cells, abnormal sebaceous gland lipid composition (such as imbalance in the proportion of free fatty acids), imbalance in Th17 / Treg cell immunity, and abnormal expression of antimicrobial peptide LL-37 jointly participate in the progression of acne. Therefore, there is an urgent need to develop a new composite formula that can synchronously regulate sebum metabolism and remove acne at the root. Summary of the Invention

[0003] Based on the solution of the above technical problems, the technical solution of the present invention is proposed. The technical solution provided by the present invention covers a composition for specifically researching and developing oil-control and acne-removing for teenagers and its application.

[0004] The composition for specifically researching and developing oil-control and acne-removing for teenagers provided by the present invention includes the following raw materials: fig fruit extract, European beech bud extract, and ganoderma lucidum extract.

[0005] In a first aspect, the present invention provides a composition for specifically researching and developing oil-control and acne-removing for teenagers. In terms of parts by mass, the oil-control and acne-removing composition includes the following raw materials: 0.1-5 parts of fig fruit extract, 0.3-3.7 parts of European beech bud extract, and 0.6-3.4 parts of ganoderma lucidum extract.

[0006] Further, in terms of parts by mass, the oil-control and acne-removing composition includes the following raw materials: 2-4 parts of fig fruit extract, 1-3 parts of European beech bud extract, and 1-3 parts of ganoderma lucidum extract.

[0007] Further, in parts by mass, the oil-control and acne-removing composition comprises the following raw materials: 3 parts of fig fruit extract, 2 parts of European beech bud extract, and 2 parts of Ganoderma lucidum extract.

[0008] Preferably, the preparation of the Ganoderma lucidum extract comprises the following steps: S1: Mix Ganoderma lucidum powder with 3 - 5 times its mass of 60wt% ethanol - aqueous solution, reflux and extract at 60 ± 5°C for 2 - 3 h, filter to obtain filtrate A and residue A; S2: Add 2 - 4 times the volume of absolute ethanol to filtrate A, centrifuge, and collect solid A and supernatant A; S3: Subject supernatant A to vacuum distillation to remove ethanol, and freeze - dry to obtain product one; S4: Mix residue A and solid A, add 3 - 5 times their mass of deionized water, ultrasonically vibrate for 1 - 2 h, filter to obtain filtrate B, dialyze filtrate B using a cellulose dialysis bag with a molecular weight cut - off of 10 - 50 kDa for the solution, and lyophilize the solution to obtain product two; wherein, the frequency of the ultrasonic vibration is 40 - 50 kHz and the temperature is 25 ± 2°C; S5: Mix product one and product two in a mass ratio of 1:0.6 - 0.8 to obtain the Ganoderma lucidum extract.

[0009] In a second aspect, the present invention provides an application of the oil - control and acne - removing composition specifically developed for teenagers as described in the first aspect in the preparation of oil - control and acne - removing cosmetics specifically developed for teenagers.

[0010] Further, the dosage form of the cosmetic is any one of cream, milk, essence, and mask.

[0011] In a third aspect, the present invention provides an oil - control and acne - removing essence water specifically developed for teenagers, and the essence water comprises the following components in mass percentage: The oil - control and acne - removing composition described in the first aspect: 0.001 - 3%; Humectant: 0.5 - 15%; Thickener: 0.1 - 5%; Antioxidant: 0.1 - 1%; Chelating agent: 0.01 - 0.1%; Deionized water is made up to 100%.

[0012] Further, the humectant includes at least one of butylene glycol, 1,2 - hexanediol, and 1,2 - pentanediol; the thickener includes xanthan gum or scleroglucan; the antioxidant includes p - hydroxyacetophenone or vitamin C; the chelating agent includes disodium EDTA.

[0013] Further, the preparation method of the essence water comprises the following steps: Step A: Mix the humectant, thickener, antioxidant, chelating agent, and deionized water evenly to obtain a mixture; Step B: Mix the mixture evenly with the oil-control and acne-removing composition to obtain essence water.

[0014] Furthermore, the mixing temperature in Step A is 70 - 90 °C, and the mixing temperature in Step B is 30 - 45 °C.

[0015] Beneficial effects: The composition of the present invention realizes four-dimensional intervention of "metabolism - keratinization - immunity - barrier" through the multi-dimensional synergistic regulation mechanism of fig fruit extract, Fagus sylvatica bud extract, and Ganoderma lucidum extract: Fig fruit extract can regulate sebum secretion by inhibiting the activity of key lipid synthesis enzymes and androgen receptor signaling pathways. Fagus sylvatica bud extract can improve abnormal follicular keratinization by blocking the activity of cell cycle kinases and regulating the keratin expression network. Ganoderma lucidum extract can strengthen the skin immune barrier by inhibiting pathogen metabolism-related immune pathways. The three work together to significantly reduce the viability of SZ95 sebaceous gland cells. After 4 weeks of actual measurement on the human body, the oil secretion reduction rate is up to 27.44% at most, and no irritation reaction occurs, breaking through the limitations of traditional single-target intervention, and providing a safe and efficient new strategy for radical acne treatment and acne therapy. Specific embodiments

[0016] The following will elaborate on the present invention in combination with specific embodiments, and various effects of the present invention will be presented more clearly therefrom. Those skilled in the art should understand that these specific embodiments are used to illustrate the present invention, rather than limiting the present invention.

[0017] Unless otherwise specifically stated, various raw materials, reagents, instruments, and equipment used in the present invention can be obtained through market purchase or can be prepared by existing methods.

[0018] The sources of raw materials in the specific embodiments of the present invention are as follows: Fig fruit extract: Purchased from Hangzhou Shiguang Xinya Biotechnology Co., Ltd.; Fagus sylvatica bud extract: Purchased from Gattefosse; Ganoderma lucidum powder: Purchased from Guangdong Microbial Technology Co., Ltd.

[0019] Composition formula and preparation for teenagers' special oil-control and acne-removing The composition formulas are all in parts by mass.

[0020] Composition 1: 3 parts of fig fruit extract, 2 parts of Fagus sylvatica bud extract, 2 parts of Ganoderma lucidum extract; The Ganoderma lucidum extract is prepared by the following preparation method: S1: Mix the Ganoderma lucidum powder with 5 times its mass of 60 wt% ethanol-aqueous solution, reflux and extract at 60 °C for 2.5 h, filter to obtain filtrate A and residue A; S2: Add 4 times the volume of absolute ethanol to filtrate A, centrifuge, and collect solid A and supernatant A; S3: Perform vacuum distillation on supernatant A to remove ethanol, and freeze-dry to obtain Product 1; S4: Mix residue A and solid A, add 5 times the mass of deionized water, ultrasonically vibrate for 1 h, filter to obtain filtrate B, dialyze filtrate B, use a cellulose dialysis bag to retain the solution with a molecular weight cut-off of 10 - 50 kDa, and lyophilize the solution to obtain Product 2; wherein, the frequency of the ultrasonic vibration is 45 kHz and the temperature is 25 °C; S5: Mix Product 1 and Product 2 in a mass ratio of 1:0.7 to obtain the Ganoderma lucidum extract.

[0021] Composition 2: 2 parts of Ficus carica fruit extract, 3 parts of Fagus sylvatica bud extract, 1 part of Ganoderma lucidum extract; The Ganoderma lucidum extract is prepared by the following method: S1: Mix the Ganoderma lucidum powder with 4 times its mass of 60 wt% ethanol-aqueous solution, reflux and extract at 65 °C for 2 h, filter to obtain filtrate A and residue A; S2: Add 3 times the volume of absolute ethanol to filtrate A, centrifuge, and collect solid A and supernatant A; S3: Perform vacuum distillation on supernatant A to remove ethanol, and freeze-dry to obtain Product 1; S4: Mix residue A and solid A, add 4 times the mass of deionized water, ultrasonically vibrate for 1.5 h, filter to obtain filtrate B, dialyze filtrate B, use a cellulose dialysis bag to retain the solution with a molecular weight cut-off of 10 - 50 kDa, and lyophilize the solution to obtain Product 2; wherein, the frequency of the ultrasonic vibration is 40 kHz and the temperature is 27 °C; S5: Mix Product 1 and Product 2 in a mass ratio of 1:0.6 to obtain the Ganoderma lucidum extract.

[0022] Composition 3: 4 parts of Ficus carica fruit extract, 1 part of Fagus sylvatica bud extract, 3 parts of Ganoderma lucidum extract; The Ganoderma lucidum extract is prepared by the following method: S1: Mix the Ganoderma lucidum powder with 3 times its mass of 60 wt% ethanol-aqueous solution, reflux and extract at 55 °C for 3 h, filter to obtain filtrate A and residue A; S2: Add 2 times the volume of absolute ethanol to filtrate A, centrifuge, and collect solid A and supernatant A; S3: Perform vacuum distillation on the supernatant A to remove ethanol, and then freeze-dry it to obtain Product 1. S4: Mix the filter residue A with Solid A, add deionized water with a mass three times that of the mixture, ultrasonically vibrate for 2 h, filter to obtain filtrate B, dialyze filtrate B using a cellulose dialysis bag with a molecular weight cut-off of 10 - 50 kDa, and lyophilize the solution to obtain Product 2; wherein, the frequency of the ultrasonic vibration is 50 kHz and the temperature is 23 °C. S5: Mix Product 1 and Product 2 at a mass ratio of 1:0.8 to obtain the Ganoderma lucidum extract.

[0023] Composition ①: Different from Composition 1, it lacks the fig fruit extract, and the missing mass fraction is made up with deionized water.

[0024] Composition ②: Different from Composition 1, it lacks the Fagus sylvatica bud extract, and the missing mass fraction is made up with deionized water.

[0025] Composition ③: Different from Composition 1, it lacks the Ganoderma lucidum extract, and the missing mass fraction is made up with deionized water.

[0026] Composition ④: Different from Composition 1, it lacks the Fagus sylvatica bud extract and the Ganoderma lucidum extract, and the missing mass fraction is made up with deionized water.

[0027] Composition ⑤: Different from Composition 1, it lacks the fig fruit extract and the Ganoderma lucidum extract, and the missing mass fraction is made up with deionized water.

[0028] Composition ⑥: Different from Composition 1, it lacks the fig fruit extract and the Fagus sylvatica bud extract, and the missing mass fraction is made up with deionized water.

[0029] Composition ⑦: Different from Composition 1, in the preparation of the Ganoderma lucidum extract, step S2 is not included, and the specific preparation steps of the Ganoderma lucidum extract are as follows: S1: Mix Ganoderma lucidum powder with a 60 wt% ethanol-aqueous solution with a mass five times that of the powder, reflux and extract at 60 °C for 2.5 h, filter to obtain filtrate A and filter residue A; S2: Perform vacuum distillation on filtrate A to remove ethanol, and then freeze-dry it to obtain Product 1. S3: Add deionized water with a mass 5 times that of the filter residue A, ultrasonically agitate for 1 h, filter to obtain filtrate B, dialyze filtrate B, use a cellulose dialysis bag to retain a solution with a molecular weight cut-off of 10 - 50 kDa, and lyophilize the solution to obtain product two; the ultrasonic agitation frequency is 45 kHz, and the ultrasonic temperature is 25°C; S4: Mix product one and product two at a mass ratio of 1:0.7 to obtain the Ganoderma lucidum extract.

[0030] Composition ⑧: Different from Composition 1, the dialysis step S2 is not included in the preparation of the Ganoderma lucidum extract. The specific preparation steps of the Ganoderma lucidum extract are as follows: S1: Mix Ganoderma lucidum powder with a 60 wt% ethanol-aqueous solution with a mass 5 times that of the powder, reflux and extract at 60°C for 2.5 h, filter to obtain filtrate A and filter residue A; S2: Add anhydrous ethanol with a volume 4 times that of filtrate A to filtrate A, centrifuge, and collect solid A and supernatant A; S3: Perform vacuum distillation on supernatant A to remove ethanol, and freeze-dry to obtain product one; S4: Mix filter residue A and solid A, add deionized water with a mass 5 times that of the mixture, ultrasonically agitate for 1 h, filter to obtain filtrate B, and lyophilize filtrate B to obtain product two; among them, the ultrasonic agitation frequency is 45 kHz and the temperature is 25°C; S5: Mix product one and product two at a mass ratio of 1:0.7 to obtain the Ganoderma lucidum extract.

[0031] Composition ⑨: Different from Composition 1, in the preparation of the Ganoderma lucidum extract, a cellulose dialysis bag is used to retain a solution with a molecular weight cut-off of 0 - 10 kDa, and the remaining steps and parameters are the same as those of Composition 1.

[0032] Composition ⑩: Different from Composition 1, in the preparation of the Ganoderma lucidum extract, a cellulose dialysis bag is used to retain a solution with a molecular weight cut-off > 50 kDa, and the remaining steps and parameters are the same as those of Composition 1.

[0033] Performance test Oil control experiment of the composition Test principle: Human sebaceous gland cells are the main sites of androgen synthesis and metabolism in the skin and also the cells with the highest androgen receptor content in the skin. Androgens have been proven to stimulate the differentiation of sebaceous gland cells, and an increase in androgen content can cause an increase in sebum secretion. In this test, the oil control effect of the composition is evaluated by comparing the effects of the test sample (composition) and the Model group (DEME medium) on the viability of human sebaceous gland cells SZ95.

[0034] Test method: This method is an in vitro method applicable to cosmetics claiming oil control efficacy. There is a certain correlation between the trend of restricting in vivo methods in relevant literature and this in vitro method. Through experimental design, the OD values of SZ95 cells in the test samples are compared with those in the Model (model group). If the OD value of SZ95 cells in the test sample group is lower than that in the Model and the statistical difference P value < 0.05, it can be considered that the test sample has a certain oil control efficacy.

[0035] Main instruments: incubator, laminar flow hood, microplate reader, pipette gun; Main reagents: DMEM medium, 5α-dihydrotestosterone, 0.25 wt% trypsin, PBS, CCK-8.

[0036] Test samples: Compositions 1-3, Compositions ①-⑩.

[0037] Preparation of test samples: The test samples are prepared as a 1.7 wt% mixture with DMEM medium and prepared as needed.

[0038] Test steps: 1. Human sebaceous gland cells SZ95 are inoculated into DMEM medium, and then 100 μL of 10 μM 5α-dihydrotestosterone is added and cultured for 72 h; 2. After the culture is completed, the cells are digested with 0.25 wt% trypsin and inoculated into 96-well plates at 5×10 3 cells / well and cultured for 24 h.

[0039] 3. After the culture is completed, the supernatant is discarded, 100 μL of the test sample is added, and an equal amount of medium is added to the Model group, and the culture is continued for 24 h.

[0040] 4. After the culture is completed, the supernatant is discarded, rinsed twice with PBS, 100 μL of medium containing 10 v / v% CCK-8 is added to each well, incubated for 2.5 h, and the cell viability is detected.

[0041] There are 3 parallels for each group of samples, and the test results (mean ± variance) are shown in Table 1.

[0042] Table 1 Effects of compositions on the viability of SZ95 cells Group OD value Model 0.436±0.05 Composition 1 0.193±0.02* Composition 2 0.197±0.02* Composition 3 0.195±0.07* Composition ① 0.289±0.14* Composition ② 0.269±0.11* Composition ③ 0.331±0.09* Composition ④ 0.376±0.06* Composition ⑤ 0.394±0.07* Composition ⑥ 0.337±0.04* Composition ⑦ 0.217±0.09* Composition ⑧ 0.225±0.14* Composition ⑨ 0.237±0.11* Composition ⑩ 0.252±0.13* Note: "*" indicates that P value < 0.05 compared with the Model.

[0043] In this experiment, by comparing the effects of the Model and the compositions on the viability of SZ95 cells, the oil control efficacy of Compositions 1-3 was observed. The results showed that Compositions 1-3 had the effect of inhibiting the proliferation of SZ95 cells, indicating that the compositions had oil control efficacy.

[0044] Comparing the results of Composition 1 with Compositions ①-⑥, it can be seen that there is a significant synergistic effect among the fig fruit extract, the Fagus sylvatica bud extract, and the Ganoderma lucidum extract in the present invention. The combined use of the three can significantly enhance the inhibitory effect on the proliferation of SZ95 cells.

[0045] Comparing the results of Composition 1 with Compositions ⑦-⑩, it can be seen that the Ganoderma lucidum extract extracted by the preparation method of Ganoderma lucidum extract defined in the present invention has better effects in the composition system provided by the present invention.

[0046] Propionibacterium acnes inhibition test Test purpose: Propionibacterium acnes is the main bacterium in acne and affects the healing of acne. In this test, the anti-acne effect of the composition was evaluated by comparing the growth inhibitory effect of the composition with that of Control (deionized water) on Propionibacterium acnes.

[0047] Relevance of test method This method is an in vitro method. For cosmetics claiming anti-acne efficacy, relevant literature shows that the trend of the in vivo method has a certain correlation with the in vitro method. Through experimental design, the diameter of the inhibition zone of Propionibacterium acnes of the test sample (composition) and Control (blank control group) was compared. If the diameter of the inhibition zone of the test sample group is greater than that of Control, it can be considered that the test sample has a certain anti-acne effect.

[0048] Test method: Main instruments: incubator, laminar flow hood, pipette, autoclave, 6 mm punch.

[0049] Main reagents: thioglycolate medium, agar powder.

[0050] Test samples: Compositions 1-3, Compositions ①-⑩; Preparation of test samples: The test samples were prepared into a 1.7 wt% mixed solution with deionized water solution and prepared as needed.

[0051] Control sample: deionized water.

[0052] Test steps: 1) Inoculate Propionibacterium acnes into thioglycolate liquid medium and culture it at 30 °C for 48 h in a constant temperature anaerobic incubator to obtain a Propionibacterium acnes suspension, and the concentration of Propionibacterium acnes in the Propionibacterium acnes suspension is 10 6 CFU / mL.

[0053] 2) Pour the thioglycollate medium containing 1.5 wt% agar powder into a petri dish. After solidification, it serves as the lower layer of the plate. Then, use a pipette to aspirate 500 μL of Propionibacterium acnes suspension and add it to 5 mL of thioglycollate medium containing 0.7 wt% agar powder cooled to 40 °C. After mixing evenly, pour it onto the lower layer of the plate. Wait for it to completely solidify to form the upper layer of the plate. Use a puncher to punch holes in the solidified upper layer of the plate. Add 100 μL of the test sample and Control to the punched holes. Place the plate in an incubator at 37 °C for 48 h. Use a vernier caliper to measure the inhibition zone. Each experiment has 3 parallels, and the diameter of the inhibition zone is represented by the average value. The test results are shown in Table 2.

[0054] Table 2 Inhibitory effect of the composition on Propionibacterium acnes Group Inhibition zone diameter / mm Control - Composition 1 26.56 Composition 2 24.37 Composition 3 26.15 Composition ① 13.44 Composition ② 16.53 Composition ③ 11.32 Composition ④ 4.33 Composition ⑤ 4.51 Composition ⑥ 7.62 Composition ⑦ 23.74 Composition ⑧ 24.73 Composition ⑨ 23.21 Composition ⑩ 21.96 Note: "-" indicates no inhibition zone.

[0055] From the comparison of the inhibitory effects of Composition 1-3, Composition ①-⑩, and Control on Propionibacterium acnes in this experiment, it can be seen that Composition 1-3 has a significant antibacterial effect, indicating that the composition provided by the present invention has the effect of removing acne.

[0056] From the comparison of the results of Composition 1 and Composition ①-⑥, it can be seen that there is a significant synergistic effect among the extracts of Ficus carica fruit, Fagus sylvatica bud, and Ganoderma lucidum in the present invention.

[0057] From the comparison of the results of Composition 1 and Composition ⑦-⑩, it can be seen that the Ganoderma lucidum extract extracted by the preparation method of Ganoderma lucidum extract defined in the present invention has better effects in the composition system provided by the present invention.

[0058] Human efficacy test Test subjects: Randomly select 130 subjects with mixed or oily skin characteristics and mild or moderate acne, aged 18-30 years.

[0059] Test samples: Essence water 1-3, Essence water ①-⑩; Preparation of test samples: The essence water includes 1.7 wt% of the oil-control and acne-removing composition, 10 wt% of the moisturizer, 1 wt% of the thickener, 0.5 wt% of the antioxidant, 0.05 wt% of the chelating agent, and make up to 100 wt% with deionized water; among them, the moisturizer is butanediol, the thickener is sclerotium gum, the antioxidant is hydroxyacetophenone, and the chelating agent is EDTA disodium; the preparation method of the test sample is as follows: Step A: Mix the moisturizer, thickener, antioxidant, chelating agent, and deionized water evenly at 80 °C to obtain a mixture; Step B: Mix the mixture with the oil-control and acne-removing composition evenly at 40°C to obtain essence water.

[0060] Among them, essence water 1-3 and the oil-control and acne-removing compositions in ①-⑩ correspond to compositions 1-3 and ①-⑩ respectively.

[0061] Test site: Face. Using the self-before-and-after control method, record the samples used by each subject.

[0062] Test method: Randomly divide the subjects into 13 groups, with 10 people in each group. Each group corresponds to 1 sample. After cleaning the face, apply 1 g of essence water to the test site, massage to absorb it, twice a day, morning and evening, for 4 consecutive weeks. Use a skin oil test probe to measure the facial oil content of the subjects, and take the average value after testing 3 times before the start of the test and after the end of the test. On the first day of the test, before the first application of the essence water, collect the satisfaction level (1-10 points) from the volunteers, and then calculate the average satisfaction level of each group. The satisfaction trend is: good effect (8-10 points) > relatively good effect (7-7.9 points) > average effect (6-6.9 points) > poor effect (4-5.9 points) > no obvious effect (2-3.9 points) > no effect (<2 points).

[0063] Rate of reduction in oil secretion = (measurement value before the start of the test - measurement value after the end of the test) / measurement value before the start of the test The test results are expressed as the average value of the rate of reduction in oil secretion of each group, as shown in Table 3 specifically.

[0064] Table 3 Human efficacy test Grouping Rate of reduced sebum secretion (%) Volunteer satisfaction Essence water 1 27.44 Good effect Essence water 2 25.37 Good effect Essence water 3 26.63 Good effect Essence water ① 16.72 Average effect Essence water ② 17.21 Average effect Essence water ③ 10.33 Average effect Essence water ④ 3.96 Poor effect Essence water ⑤ 1.57 No obvious effect Essence water ⑥ 6.44 Poor effect Essence water ⑦ 20.37 Good effect Essence water ⑧ 23.39 Good effect Essence water ⑨ 22.52 Good effect Essence water ⑩ 21.21 Good effect According to the human efficacy test results, it can be known that essence water 1-3 and essence water ①-⑩ in the present invention all have a certain effect of reducing facial oil secretion.

[0065] Those skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if these modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalent technologies, the present invention is also intended to include these modifications and variations.

Claims

1. A composition specifically developed for teenagers to control oil and remove acne, characterized in that, The oil-control and acne-removing composition comprises the following raw materials: fig fruit extract, Fagus sylvatica bud extract, and Ganoderma lucidum extract.

2. The composition for controlling oil and removing acne according to claim 1, wherein By mass, the oil-control and acne-removing composition comprises the following raw materials: 0.1 - 5 parts of fig fruit extract, 0.3 - 3.7 parts of Fagus sylvatica bud extract, and 0.6 - 3.4 parts of Ganoderma lucidum extract.

3. The oil-control and acne-removing composition according to claim 2, wherein By mass, the oil-control and acne-removing composition comprises the following raw materials: 2 - 4 parts of fig fruit extract, 1 - 3 parts of Fagus sylvatica bud extract, and 1 - 3 parts of Ganoderma lucidum extract.

4. The composition for controlling oil and removing acne according to claim 3, wherein By mass, the oil-control and acne-removing composition comprises the following raw materials: 3 parts of fig fruit extract, 2 parts of Fagus sylvatica bud extract, and 2 parts of Ganoderma lucidum extract.

5. The oil-control and acne-removing composition according to any one of claims 1-4, wherein The preparation of the Ganoderma lucidum extract comprises the following steps: S1: Mix Ganoderma lucidum powder with 3 - 5 times the mass of 60wt% ethanol-aqueous solution, reflux and extract at 60 ± 5°C for 2 - 3 h, filter to obtain filtrate A and residue A; S2: Add 2 - 4 times the volume of absolute ethanol to filtrate A, centrifuge, and collect solid A and supernatant A; S3: Perform vacuum distillation on supernatant A to remove ethanol, and freeze-dry to obtain product one; S4: Mix residue A with solid A, add 3 - 5 times the mass of deionized water, ultrasonically vibrate for 1 - 2 h, filter to obtain filtrate B, dialyze filtrate B, use a cellulose dialysis bag to retain the solution with a molecular weight cut-off of 10 - 50 kDa, and freeze-dry the solution to obtain product two; wherein, the frequency of the ultrasonic vibration is 40 - 50 kHz and the temperature is 25 ± 2°C; S5: Mix product one and product two according to a mass ratio of 1:0.6 - 0.8 to obtain Ganoderma lucidum extract.

6. Use of the composition for specifically researching oil-control and acne-removing for teenagers according to any one of claims 1 - 5 in the preparation of cosmetics for specifically researching oil-control and acne-removing for teenagers.

7. The application according to claim 6, characterized in that, The dosage form of the cosmetics is any one of cream, milk, essence, and mask.

8. An essence water specifically developed for teenagers to control oil and remove acne, characterized in that, The essence water comprises the following components by mass percentage: 0.001 - 3% of the oil-control and acne-removing composition according to any one of claims 1 - 5; 0.5 - 15% of a humectant; 0.1 - 5% of a thickener; 0.1 - 1% of an antioxidant; 0.01 - 0.1% of a chelating agent; Make up deionized water to 100%.

9. The essence water according to claim 8, characterized in that, Among them, the humectant includes at least one of butylene glycol, 1,2 - hexanediol, and 1,2 - pentanediol; the thickener includes xanthan gum or scleroglucan; the antioxidant includes p-hydroxyacetophenone or vitamin C; the chelating agent includes disodium EDTA.

10. The essence water according to claim 8 or 9, characterized in that, The preparation method of the essence water comprises the following steps: Step A: Mix the humectant, thickener, antioxidant, chelating agent, and deionized water evenly to obtain a mixture; Step B: Mix the mixture with the oil-control and acne-removing composition evenly to obtain essence water; Among them, the mixing temperature in step A is 70 - 90°C, and the mixing temperature in step B is 30 - 45°C.