Temperature measurement and control system for radio frequency heating treatment in bladder cavity

Abstract

The invention relates to a temperature measurement and control system for radio frequency heating treatment in a bladder cavity, which comprises a radio frequency output electrode, a temperature measurement probe, a radio frequency output negative plate, a radio frequency generation device, a radio frequency power acquisition device, a temperature acquisition device, a control system, a computer and a touch display, the radio frequency output electrode is connected with the radio frequency generating device, the temperature measuring probe is connected with the radio frequency output electrode, the radio frequency power collecting device is connected with the radio frequency output electrode, the radio frequency power collecting device is connected with the control system, the temperature collecting device is connected with the temperature measuring probe, the temperature collecting device is connected with the control system, and the control system is connected with the computer. And the radio frequency output negative plate is connected with the radio frequency generator. According to the temperature measurement and control system, heat is generated near the radio frequency output electrode to heat liquid around the electrode; the temperature of liquid in the bladder cavity is monitored in real time through the temperature measuring probe, and normal saline added with chemotherapy in the bladder cavity is heated to 43-45 DEG C for thermal chemotherapy.

Description

Technical Field

[0001] The present invention relates to the field of measurement and control technology, and in particular to a temperature measurement and control system for radiofrequency heating treatment in a bladder cavity. Background Art

[0002] Bladder cancer is a common malignant tumor of the urinary system worldwide, with a higher incidence rate in men in particular. Based on the high recurrence rate of bladder cancer, the limitations of existing treatment methods and the unique biological mechanism of hyperthermia. Bladder hyperthermia perfusion therapy is a local treatment method that combines hyperthermia and chemotherapy, mainly used for non-muscle invasive bladder cancer. By combining hyperthermia and chemotherapy, bladder hyperthermia perfusion therapy is expected to significantly reduce the recurrence rate of NMIBC, improve patient prognosis, and meet unmet clinical needs. With the continuous development of clinical research and technology, the status of bladder hyperthermia perfusion therapy in the comprehensive treatment of bladder cancer will be further enhanced. However, the existing bladder radiofrequency intracavitary thermal chemotherapy device has a simple heating method and can only treat the surface of the organ, but cannot penetrate the organ tissue for deep treatment. It fails to provide treatment parameters and temperature measurement curves of important organs, which is not conducive to real-time monitoring, and the effect of treatment with chemotherapy drugs is not ideal. Summary of the Invention

[0003] In order to overcome the shortcomings and deficiencies in the prior art, the purpose of the present invention is to provide a temperature measurement and control system for radiofrequency heating therapy in the bladder cavity. The system can precisely control the radiofrequency power and generate heat near the radiofrequency output electrode through ion oscillation at the particle level, thereby heating the liquid around the electrode; the temperature of the liquid in the bladder cavity is monitored in real time through a temperature measuring probe in the radiofrequency output electrode, and the normal saline solution with chemotherapy added in the bladder cavity is heated to 43-45°C for thermal chemotherapy.

[0004] The objectives of the present invention are achieved through the following technical solutions: A temperature measurement and control system for radio frequency heating treatment in the bladder cavity, comprising a radio frequency output electrode, a temperature measuring probe, a radio frequency output negative plate, a radio frequency generator, a radio frequency power acquisition device, a temperature acquisition device, a control system, a computer and a touch display, one end of the control system is connected to the radio frequency generator, the radio frequency output electrode is connected to the output end of the radio frequency generator, one end of the temperature measuring probe is connected to the radio frequency output electrode, one end of the radio frequency power acquisition device is connected to the radio frequency output electrode, the other end of the radio frequency power acquisition device is connected to the control system, one end of the temperature acquisition device is connected to the temperature measuring probe, the other end of the temperature acquisition device is connected to the control system, the other end of the control system is connected to the computer, the touch display is connected to the computer, and the radio frequency output negative plate is connected to the other output end of the radio frequency generator.

[0005] Preferably, the RF output negative electrode plate is a conductive adhesive negative electrode plate.

[0006] Preferably, the radio frequency output electrode is a stainless steel tube with a diameter of 2.8-3.2 mm, and the front end is sealed with a spherical block.

[0007] Preferably, the temperature measuring probe is an optical fiber sensor with a diameter of 0.4-0.6 mm, which is inserted into the top of the radio frequency output electrode through mechanical fitting and is sealed and fixed using medical glue.

[0008] Preferably, the radio frequency generating device is connected to the radio frequency output electrode via an aviation plug and a cable to output radio frequency energy.

[0009] The temperature measurement and control system used for radiofrequency heating treatment in the bladder cavity in the present invention can generate heat near the radiofrequency output electrode through ion oscillation at the particle level by precisely controlling the radiofrequency power, thereby heating the liquid around the electrode; the temperature of the liquid in the bladder cavity is monitored in real time through the temperature measuring probe in the radiofrequency output electrode, and the physiological saline with chemotherapy in the bladder cavity is heated to 43-45°C for thermal chemotherapy. Specifically, the temperature probe is embedded in the RF output electrode and connected to the RF output interface of the RF generator, outputting RF energy and real-time monitoring of the liquid temperature near the RF output electrode, with an RF output power accuracy of ±1W and a temperature measurement accuracy of ±0.1°C. The RF output negative plate is a conductive adhesive negative plate, usually attached to a smooth skin surface (such as the back or thigh), and participates in forming a complete RF output circuit. The RF generator is used to generate a maximum RF power of no more than 100W with an output power accuracy of ±1W. The RF output circuit is composed of the RF output electrode and the RF output negative plate, generating ion-level oscillations near the RF output electrode, generating RF energy to heat the liquid in the bladder cavity. The RF power acquisition device can collect the output RF power in real time with a measurement accuracy of ±0.1W. The RF output power is adjusted in real time based on the feedback power data to achieve precise control of the RF power. The temperature acquisition device is embedded in the temperature probe on the RF output electrode, with a measurement accuracy of ±0. 1℃, with a resolution of up to 0.01℃, for real-time liquid temperature monitoring in the bladder, temperature data is fed back to the computer control system, and the RF power output is controlled in real time through the temperature control algorithm, so that the liquid temperature in the bladder is controlled within a deviation range of ±0.3℃ from the computer set temperature; the control system controls the RF output power of the RF generator, receives the RF power data fed back by the RF power acquisition device in real time, and adjusts the RF output power control in real time through the calculation software algorithm, receives the temperature data of the temperature acquisition device in real time, feeds it back to the computer for comparison with the set temperature, performs real-time temperature control and regulation, and exchanges data with the computer through the communication interface; the touch display displays the set RF output power, modifies the set RF output power number by touching, displays the bladder cavity temperature setting data, modifies the bladder cavity temperature setting data by touching, receives the fed-back power data and the fed-back real-time bladder cavity liquid temperature in real time, and displays the icon curve of time-bladder cavity temperature-RF output power.

[0010] Preferably, the conductive adhesive negative electrode plate is made of conductive adhesive, and the conductive adhesive includes the following raw materials in parts by weight: 20-70 parts of conductive material, 30-60 parts of adhesive, 20-40 parts of solvent, 0.5-5 parts of thickener, and 0.1-2 parts of functional additive; the thickener is carbomer, which can improve colloid stability.

[0011] Preferably, the conductive material is at least one of silver, silver chloride, carbon-based material, and ion conductive material; the carbon-based material is carbon fiber, conductive carbon powder, or graphite powder, and the ion conductive material is preferably polyelectrolyte gel.

[0012] The conductive material used in the conductive adhesive of the present invention can provide a current path to ensure uniform conductivity.

[0013] Silver or silver chloride used in the conductive material of the present invention has high conductivity and anti-polarization, making it the first choice for medical electrodes; carbon-based materials have lower costs, but their conductivity is slightly inferior to silver; ion conductive materials conduct electricity through ion migration and need to be compatible with adhesives.

[0014] Preferably, the adhesive is at least one of a hydrogel, a silicone matrix, and a polyurethane glue; the hydrogel is preferably polyacrylate or polyvinyl alcohol. The adhesive can fix the conductive material and provide adhesion (fitting the skin). The hydrogel used has the characteristics of good biocompatibility and strong water retention; the silicone matrix has high flexibility; the polyurethane glue has strong adhesion and needs to be used with a plasticizer to adjust the hardness.

[0015] Preferably, the solvent is at least one of deionized water, glycerol, and propylene glycol. The solvent can adjust the rheological properties of the colloid, facilitating coating and storage. Glycerol / propylene glycol are the primary solvents in the hydrogel system, acting as humectants to prevent the gel from drying out.

[0016] Preferably, the functional additives include a preservative, a pH regulator and an anti-allergic component; the preservative is phenoxyethanol; the pH regulator is triethanolamine; and the anti-allergic component is aloe extract.

[0017] The phenoxyethanol used as a preservative in the present invention has the function of preventing the growth of microorganisms; the pH regulator (such as triethanolamine) can maintain the acid-base balance of the colloid; and the anti-allergic ingredient (such as aloe vera extract) can reduce the risk of skin irritation.

[0018] Preferably, the conductive adhesive is prepared by the following method:

[0019] S1. Mix the conductive materials uniformly according to weight to obtain a mixed conductive material for later use;

[0020] S2. Add the thickener and the mixed electrical material to the solvent according to parts by weight, stir evenly to obtain a mixture, and set aside;

[0021] S3. Mix the adhesive and the functional additive according to parts by weight and add the mixture to the mixture obtained in step S2. Stir the mixture at a speed of 500-800 rpm to obtain a conductive adhesive.

[0022] RF output electrode, temperature measuring probe, RF output negative plate, RF generator, RF power acquisition device, temperature acquisition device, control system, computer and touch display

[0023] The beneficial effects of the present invention are:

[0024] 1. The present invention directly heats the liquid in the bladder cavity through radio frequency energy, which can achieve precise control of radio frequency energy output, and the heating energy work resolution can reach ±0.1W.

[0025] 2. The RF output electrode is embedded with a temperature measuring probe, which has a temperature measurement accuracy of ±0.1°C. It can monitor the temperature of the liquid in the bladder cavity in real time, and then adjust the temperature of the liquid in the bladder cavity by adjusting the RF energy output in real time, so as to achieve precise control of the temperature in the bladder cavity with a temperature control accuracy of ±0.3°C.

[0026] 3. Radio frequency heating energy directly acts on the liquid in the bladder cavity. The efficiency of converting radio frequency energy into heat is as high as over 95%. Only a small radio frequency energy output is required to achieve precise temperature control.

[0027] 4. The present invention uses a computer control system to establish an intelligent big data model to intelligently calculate the liquid volume of different bladder cavities and output radio frequency energy to achieve high-precision temperature control of the liquid in the bladder cavity.

[0028] 5. The present invention uses a touch display to set the current control temperature in the bladder cavity by touching, and displays the real-time feedback of the liquid temperature in the bladder cavity. At the same time, it establishes a time-RF output power-bladder cavity temperature icon curve display, which is convenient for medical staff to view historical data and conduct treatment evaluation. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] Figure 1 It is a structural schematic diagram of the temperature measurement and control system of the present invention.

[0030] The accompanying drawings are marked as follows: 1-RF output electrode, 2-temperature measuring probe, 3-RF output negative plate, 4-RF generating device, 5-RF power acquisition device, 6-temperature acquisition device, 7-control system, 8-computer, 9-touch display. DETAILED DESCRIPTION

[0031] In order to facilitate the understanding of those skilled in the art, the following embodiments and accompanying drawings are provided. Figure 1 The present invention is further described, and the contents mentioned in the embodiment are not intended to limit the present invention.

[0032] It should be noted that when an element is referred to as being “fixed to” or “disposed on” another element, it can be directly on the other element or indirectly on the other element.

[0033] When an element is referred to as being “connected to” another element, it can be directly connected to the another element or indirectly connected to the another element.

[0034] It should be understood that the terms "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the accompanying drawings, and are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on this application.

[0035] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be understood to indicate or imply relative importance or to implicitly indicate the quantity of the technical features indicated. Thus, a feature specified as "first" or "second" may explicitly or implicitly include one or more of the features.

[0036] In the description of the present application, “plurality” means two or more, unless otherwise clearly defined.

[0037] Example 1

[0038] See Figure 1 A temperature measurement and control system for radiofrequency heating treatment in the bladder cavity includes a radiofrequency output electrode 1, a temperature measuring probe 2, a radiofrequency output negative plate 3, a radiofrequency generator 4, a radiofrequency power acquisition device 5, a temperature acquisition device 6, a control system 7, a computer 8 and a touch display 9. One end of the control system 7 is connected to the radiofrequency generator 4, the radiofrequency output electrode 1 is connected to the output end of the radiofrequency generator 4, one end of the temperature measuring probe 2 is connected to the radiofrequency output electrode 1, one end of the radiofrequency power acquisition device 5 is connected to the radiofrequency output electrode 1, the other end of the radiofrequency power acquisition device 5 is connected to the control system 7, one end of the temperature acquisition device 6 is connected to the temperature measuring probe 2, the other end of the temperature acquisition device 6 is connected to the control system 7, the other end of the control system 7 is connected to the computer 8, the touch display 9 is connected to the computer 8, and the radiofrequency output negative plate 3 is connected to the other output end of the radiofrequency generator 4.

[0039] In this embodiment, the temperature probe 2 is embedded in the RF output electrode 1. The RF output electrode 1 is a 3mm diameter stainless steel tube with a spherical block sealed at the front end. The temperature probe 2 is a 0.5mm diameter optical fiber sensor mechanically inserted into the top of the RF output electrode 1 and sealed with medical glue. The RF generator 4 is connected to the RF output electrode 1 via an aviation plug and cable to output RF energy, obtains power energy through the power supply interface, receives RF startup and power output data from the control system 7 via the serial communication interface, and activates the RF generator 4 and outputs the corresponding energy output. The RF power collection device 5 is configured by adding an RF current and RF voltage collection circuit to the cable connecting the RF output electrode 1 and the RF output negative plate 3 (the RF output negative plate 3 is a conductive adhesive negative plate). The RF current collection circuit converts the RF current AC voltage signal into a 0-5V DC voltage signal, which is then connected to the voltage collection port of the control system 7 for conversion into a digital signal. Similarly, the RF voltage digital signal conversion is performed; the temperature measuring probe 2 senses the temperature of the liquid in the bladder in real time, converts it into a photoelectric signal, and transmits the photoelectric signal to the temperature collection device 6, which converts it into a temperature digital signal. The digital signal is transmitted to the control system 7 via serial communication; the control system 7 is connected to the RF generator 4 via a serial communication interface. The control system 7 is connected to the RF current conversion signal interface and the RF voltage conversion signal interface of the RF power acquisition device 5 through the voltage acquisition port to obtain the RF voltage and RF current in real time, and calculate the real-time RF power through the conversion formula. The control system 7 is connected to the computer 8 through the serial communication interface for data interaction and control; the computer 8 is connected to the control system 7 for serial communication to start the RF generating device 4 and transmit the RF power data information, control the setting value of the temperature in the bladder cavity, and interact with the touch display module to set the RF power and temperature control information, draw curves, etc.; the touch display module is connected to the computer 8 for human-computer interaction settings and displays.

[0040] Example 2

[0041] A temperature measurement and control system for radiofrequency heating treatment in the bladder cavity, comprising a radiofrequency output electrode 1, a temperature measuring probe 2, a radiofrequency output negative plate 3, a radiofrequency generator 4, a radiofrequency power acquisition device 5, a temperature acquisition device 6, a control system 7, a computer 8 and a touch display 9, wherein one end of the control system 7 is connected to the radiofrequency generator 4, the radiofrequency output electrode 1 is connected to the output end of the radiofrequency generator 4, one end of the temperature measuring probe 2 is connected to the radiofrequency output electrode 1, one end of the radiofrequency power acquisition device 5 is connected to the radiofrequency output electrode 1, the other end of the radiofrequency power acquisition device 5 is connected to the control system 7, one end of the temperature acquisition device 6 is connected to the temperature measuring probe 2, the other end of the temperature acquisition device 6 is connected to the control system 7, the other end of the control system 7 is connected to the computer 8, the touch display 9 is connected to the computer 8, and the radiofrequency output negative plate 3 is connected to the other output end of the radiofrequency generator 4.

[0042] The RF output negative electrode plate 3 is a conductive adhesive negative electrode plate; the conductive adhesive negative electrode plate is made of conductive adhesive, and the conductive adhesive includes the following raw materials in parts by weight: 20 parts of conductive material, 30 parts of adhesive, 20 parts of solvent, 0.5 parts of thickener, and 0.1 parts of functional additive; the thickener is carbomer.

[0043] The conductive material is silver chloride.

[0044] The adhesive is a hydrogel; the hydrogel is preferably polyacrylate.

[0045] The solvent is composed of deionized water and propylene glycol in a mass ratio of 1:1.

[0046] The functional additives include a preservative, a pH regulator and an anti-allergic component; the preservative is phenoxyethanol; the pH regulator is triethanolamine; and the anti-allergic component is aloe extract.

[0047] The conductive adhesive is prepared by the following method:

[0048] S1. Mix the conductive materials uniformly according to weight to obtain a mixed conductive material for later use;

[0049] S2. Add the thickener and the mixed electrical material to the solvent according to parts by weight, stir evenly to obtain a mixture, and set aside;

[0050] S3. Mix the adhesive and the functional additive according to parts by weight and add the mixture to the mixture obtained in step S2. Stir the mixture at a speed of 500 rpm to obtain a conductive adhesive.

[0051] Example 3

[0052] A temperature measurement and control system for radiofrequency heating treatment in the bladder cavity, comprising a radiofrequency output electrode 1, a temperature measuring probe 2, a radiofrequency output negative plate 3, a radiofrequency generator 4, a radiofrequency power acquisition device 5, a temperature acquisition device 6, a control system 7, a computer 8 and a touch display 9, wherein one end of the control system 7 is connected to the radiofrequency generator 4, the radiofrequency output electrode 1 is connected to the output end of the radiofrequency generator 4, one end of the temperature measuring probe 2 is connected to the radiofrequency output electrode 1, one end of the radiofrequency power acquisition device 5 is connected to the radiofrequency output electrode 1, the other end of the radiofrequency power acquisition device 5 is connected to the control system 7, one end of the temperature acquisition device 6 is connected to the temperature measuring probe 2, the other end of the temperature acquisition device 6 is connected to the control system 7, the other end of the control system 7 is connected to the computer 8, the touch display 9 is connected to the computer 8, and the radiofrequency output negative plate 3 is connected to the other output end of the radiofrequency generator 4.

[0053] The RF output negative electrode plate 3 is a conductive adhesive negative electrode plate; the conductive adhesive negative electrode plate is made of conductive adhesive, and the conductive adhesive includes the following raw materials in parts by weight: 50 parts of conductive material, 45 parts of adhesive, 30 parts of solvent, 3 parts of thickener, and 1 part of functional additive; the thickener is carbomer.

[0054] The conductive material is a silver-carbon-based material; and the carbon-based material is a carbon fiber.

[0055] The adhesive is polyurethane glue.

[0056] The solvent is composed of deionized water and glycerol in a mass ratio of 1:1.

[0057] The functional additives include a preservative, a pH regulator and an anti-allergic component; the preservative is phenoxyethanol; the pH regulator is triethanolamine; and the anti-allergic component is aloe extract.

[0058] The conductive adhesive is prepared by the following method:

[0059] S1. Mix the conductive materials uniformly according to weight to obtain a mixed conductive material for later use;

[0060] S2. Add the thickener and the mixed electrical material to the solvent according to parts by weight, stir evenly to obtain a mixture, and set aside;

[0061] S3. Mix the adhesive and the functional additive according to parts by weight and add the mixture to the mixture obtained in step S2. Stir the mixture at a speed of 700 rpm to obtain a conductive adhesive.

[0062] Example 4

[0063] A temperature measurement and control system for radiofrequency heating treatment in the bladder cavity, comprising a radiofrequency output electrode 1, a temperature measuring probe 2, a radiofrequency output negative plate 3, a radiofrequency generator 4, a radiofrequency power acquisition device 5, a temperature acquisition device 6, a control system 7, a computer 8 and a touch display 9, wherein one end of the control system 7 is connected to the radiofrequency generator 4, the radiofrequency output electrode 1 is connected to the output end of the radiofrequency generator 4, one end of the temperature measuring probe 2 is connected to the radiofrequency output electrode 1, one end of the radiofrequency power acquisition device 5 is connected to the radiofrequency output electrode 1, the other end of the radiofrequency power acquisition device 5 is connected to the control system 7, one end of the temperature acquisition device 6 is connected to the temperature measuring probe 2, the other end of the temperature acquisition device 6 is connected to the control system 7, the other end of the control system 7 is connected to the computer 8, the touch display 9 is connected to the computer 8, and the radiofrequency output negative plate 3 is connected to the other output end of the radiofrequency generator 4.

[0064] The RF output negative electrode plate 3 is a conductive adhesive negative electrode plate; the conductive adhesive negative electrode plate is made of conductive adhesive, and the conductive adhesive includes the following raw materials in parts by weight: 70 parts of conductive material, 60 parts of adhesive, 40 parts of solvent, 5 parts of thickener, and 2 parts of functional additive; the thickener is carbomer.

[0065] The conductive material is an ion conductive material; the carbon ion conductive material is preferably a polyelectrolyte gel.

[0066] The adhesive is a hydrogel; the hydrogel is preferably polyvinyl alcohol.

[0067] The solvent is composed of deionized water and propylene glycol in a mass ratio of 1:1.

[0068] The functional additives include a preservative, a pH regulator and an anti-allergic component; the preservative is phenoxyethanol; the pH regulator is triethanolamine; and the anti-allergic component is aloe extract.

[0069] The conductive adhesive is prepared by the following method:

[0070] S1. Mix the conductive materials uniformly according to weight to obtain a mixed conductive material for later use;

[0071] S2. Add the thickener and the mixed electrical material to the solvent according to parts by weight, stir evenly to obtain a mixture, and set aside;

[0072] S3. Mix the adhesive and the functional additive according to parts by weight and add the mixture to the mixture obtained in step S2. Stir the mixture at a speed of 800 rpm to obtain a conductive adhesive.

[0073] Example 5

[0074] A temperature measurement and control system for radiofrequency heating treatment in the bladder cavity, comprising a radiofrequency output electrode 1, a temperature measuring probe 2, a radiofrequency output negative plate 3, a radiofrequency generator 4, a radiofrequency power acquisition device 5, a temperature acquisition device 6, a control system 7, a computer 8 and a touch display 9, wherein one end of the control system 7 is connected to the radiofrequency generator 4, the radiofrequency output electrode 1 is connected to the output end of the radiofrequency generator 4, one end of the temperature measuring probe 2 is connected to the radiofrequency output electrode 1, one end of the radiofrequency power acquisition device 5 is connected to the radiofrequency output electrode 1, the other end of the radiofrequency power acquisition device 5 is connected to the control system 7, one end of the temperature acquisition device 6 is connected to the temperature measuring probe 2, the other end of the temperature acquisition device 6 is connected to the control system 7, the other end of the control system 7 is connected to the computer 8, the touch display 9 is connected to the computer 8, and the radiofrequency output negative plate 3 is connected to the other output end of the radiofrequency generator 4.

[0075] The RF output negative electrode plate 3 is a conductive adhesive negative electrode plate; the conductive adhesive negative electrode plate is made of conductive adhesive, and the conductive adhesive includes the following raw materials in parts by weight: 20 parts of conductive material, 50 parts of adhesive, 20 parts of solvent, 0.5 parts of thickener, and 1 part of functional additive; the thickener is carbomer.

[0076] The conductive material is silver / silver chloride.

[0077] The adhesive is a hydrogel; the hydrogel is preferably a polyacrylate hydrogel.

[0078] The solvent is composed of deionized water and glycerol in a mass ratio of 1:1.

[0079] The functional additive is composed of a preservative and a pH regulator in a mass ratio of 1:1; the preservative is phenoxyethanol; and the pH regulator is triethanolamine.

[0080] The conductive adhesive is prepared by the following method:

[0081] S1. Mix the conductive materials uniformly according to weight to obtain a mixed conductive material for later use;

[0082] S2. Add the thickener and the mixed electrical material to the solvent according to parts by weight, stir evenly to obtain a mixture, and set aside;

[0083] S3. Mix the adhesive and the functional additive according to parts by weight and add the mixture to the mixture obtained in step S2. Stir the mixture at a speed of 600 rpm to obtain a conductive adhesive.

[0084] Example 6

[0085] A temperature measurement and control system for radiofrequency heating treatment in the bladder cavity, comprising a radiofrequency output electrode 1, a temperature measuring probe 2, a radiofrequency output negative plate 3, a radiofrequency generator 4, a radiofrequency power acquisition device 5, a temperature acquisition device 6, a control system 7, a computer 8 and a touch display 9, wherein one end of the control system 7 is connected to the radiofrequency generator 4, the radiofrequency output electrode 1 is connected to the output end of the radiofrequency generator 4, one end of the temperature measuring probe 2 is connected to the radiofrequency output electrode 1, one end of the radiofrequency power acquisition device 5 is connected to the radiofrequency output electrode 1, the other end of the radiofrequency power acquisition device 5 is connected to the control system 7, one end of the temperature acquisition device 6 is connected to the temperature measuring probe 2, the other end of the temperature acquisition device 6 is connected to the control system 7, the other end of the control system 7 is connected to the computer 8, the touch display 9 is connected to the computer 8, and the radiofrequency output negative plate 3 is connected to the other output end of the radiofrequency generator 4.

[0086] The RF output negative electrode plate 3 is a conductive adhesive negative electrode plate; the conductive adhesive negative electrode plate is made of conductive adhesive, and the conductive adhesive includes the following raw materials in parts by weight: 35 parts of conductive material, 50 parts of adhesive, 20 parts of solvent, 0.5 parts of thickener, and 2 parts of functional additive; the thickener is carbomer.

[0087] The conductive material is a carbon-based material; the carbon-based material is conductive carbon powder.

[0088] The adhesive is a silicone matrix; the silicone matrix is preferably a medical silicone matrix.

[0089] The solvent is composed of deionized water and propylene glycol in a mass ratio of 1:1.

[0090] The functional additives include plasticizers and antistatic agents; the plasticizer is silicone oil.

[0091] The conductive adhesive is prepared by the following method:

[0092] S1. Mix the conductive materials uniformly according to weight to obtain a mixed conductive material for later use;

[0093] S2. Add the thickener and the mixed electrical material to the solvent according to parts by weight, stir evenly to obtain a mixture, and set aside;

[0094] S3. Mix the adhesive and the functional additive according to parts by weight and add the mixture to the mixture obtained in step S2. Stir the mixture at a speed of 600 rpm to obtain a conductive adhesive.

[0095] The performance test of the conductive adhesive prepared in Example 5 was carried out:

[0096] Conductivity: Surface resistance needs to be less than 1Ω·cm 2 , ensuring even current distribution.

[0097] Biocompatibility: ISO 10993 certified (cytotoxicity, skin irritation tests).

[0098] Adhesion: Adhesive to the skin and easy to peel off without residue (peel force is typically 0.1–1N / cm).

[0099] Durability: Maintains stable performance in humid environments.

[0100] The above embodiments are preferred implementation schemes of the present invention. In addition, the present invention can also be implemented in other ways. Any obvious replacement without departing from the concept of the present invention is within the scope of protection of the present invention.

Claims

1. A temperature measurement and control system for radiofrequency heating therapy in the bladder cavity, characterized by: The invention comprises a radio frequency output electrode, a temperature measuring probe, a radio frequency output negative plate, a radio frequency generator, a radio frequency power collection device, a temperature collection device, a control system, a computer and a touch display. One end of the control system is connected to the radio frequency generator, the radio frequency output electrode is connected to the output end of the radio frequency generator, one end of the temperature measuring probe is connected to the radio frequency output electrode, one end of the radio frequency power collection device is connected to the radio frequency output electrode, the other end of the radio frequency power collection device is connected to the control system, one end of the temperature collection device is connected to the temperature measuring probe, the other end of the temperature collection device is connected to the control system, the other end of the control system is connected to the computer, the touch display is connected to the computer, and the radio frequency output negative plate is connected to the other output end of the radio frequency generator.

2. A temperature measurement and control system for radiofrequency heating therapy in the bladder cavity according to claim 1, characterized in that: The radio frequency output negative electrode plate adopts a conductive adhesive negative electrode plate.

3. The temperature measurement and control system for radiofrequency heating therapy in the bladder cavity according to claim 1, characterized in that: The radio frequency output electrode is a stainless steel tube with a diameter of 2.8-3.2 mm, and the front end is sealed with a spherical block.

4. The temperature measurement and control system for radiofrequency heating therapy in the bladder cavity according to claim 1, characterized in that: The temperature measuring probe is an optical fiber sensor with a diameter of 0.4-0.6 mm, which is inserted into the top of the radio frequency output electrode through mechanical matching and is sealed and fixed using medical glue.

5. The temperature measurement and control system for radiofrequency heating therapy in the bladder cavity according to claim 1, characterized in that: The radio frequency generating device is connected to the radio frequency output electrode through an aviation plug and a cable to output radio frequency energy.

6. The temperature measurement and control system for radiofrequency heating therapy in the bladder cavity according to claim 2, characterized in that: The conductive adhesive negative plate is made of conductive adhesive, which includes the following raw materials in parts by weight: 20-70 parts of conductive material, 30-60 parts of adhesive, 20-40 parts of solvent, 0.5-5 parts of thickener, and 0.1-2 parts of functional additives.

7. The temperature measurement and control system for radiofrequency heating therapy in the bladder cavity according to claim 6, characterized in that: The conductive material is at least one of silver, silver chloride, carbon-based materials, and ion conductive materials.

8. The temperature measurement and control system for radiofrequency heating therapy in the bladder cavity according to claim 6, characterized in that: The adhesive is at least one of hydrogel, silicone matrix, and polyurethane glue.

9. The temperature measurement and control system for radiofrequency heating therapy in the bladder cavity according to claim 6, characterized in that: The solvent is at least one of deionized water, glycerol, and propylene glycol.

10. A temperature measurement and control system for radiofrequency heating therapy in the bladder cavity according to any one of claims 6 to 9, characterized in that: The conductive adhesive is prepared by the following method: S1. Mix the conductive materials uniformly according to weight to obtain a mixed conductive material for later use; S2. Add the thickener and the mixed electrical material to the solvent according to parts by weight, stir evenly to obtain a mixture, and set aside; S3. Mix the adhesive and the functional additive according to parts by weight and add the mixture to the mixture obtained in step S2. Stir the mixture at a speed of 500-800 rpm to obtain a conductive adhesive.

Images