Sanitary napkin containing traditional Chinese medicine extract capable of clearing heat, removing dampness and relieving itching

Abstract

The invention discloses a sanitary napkin containing traditional Chinese medicine extracts capable of clearing heat, removing dampness and relieving itching in the field of hygienic products, which comprises a surface layer, a bacteriostatic absorption layer and a bottom film layer which are sequentially arranged from inside to outside, the bacteriostatic absorption layer is used for absorbing menstrual blood and avoiding leakage and infection, and the bacteriostatic absorption layer is sprayed with a bacteriostatic composition; a sustained-release chip is fixedly connected to the center of the antibacterial absorption layer, the sustained-release chip is used for diffusing traditional Chinese medicine components into the antibacterial absorption layer to achieve the effects of clearing damp, relieving itching, clearing heat and inhibiting bacteria, and the sustained-release chip contains an organic phase change capsule prepared from a traditional Chinese medicine concentrated solution. The sanitary towel is novel and effective, the functions of clearing heat, eliminating dampness, relieving itching and inhibiting bacteria of the sanitary towel are achieved by combining the traditional Chinese medicine formula extract with the organic phase change capsule technology, short-term menstrual blood absorption and pudendum sanitation are emphasized, menstrual period symptoms of female heat-dampness signs are improved in the long-term process, and pudendum health is protected.

Description

Technical Field

[0001] The invention belongs to the field of sanitary products, in particular to a sanitary napkin containing a traditional Chinese medicine extract for clearing away heat, dehumidifying and relieving itching. Background Art

[0002] In the field of women's menstrual care, sanitary napkins are essential products for women during menstruation. As people pay more attention to health and comfort, the demand for them continues to grow. However, the products currently on the market still have some areas that need to be improved.

[0003] Traditional sanitary napkins primarily focus on absorbing menstrual blood and maintaining dryness and comfort. However, targeted solutions for the many issues women face during menstruation, such as vulvar itching and odorous discharge, are often unsatisfactory. Gynecological conditions such as vulvitis and vaginitis are more likely to develop and worsen during menstruation, manifesting as vulvar itching, burning pain, and abnormal vaginal discharge, causing significant discomfort and distress. Furthermore, physiological changes and environmental changes during menstruation make the vagina more susceptible to bacterial invasion, leading to infections and other problems.

[0004] Currently, some sanitary napkins with antibacterial functions can temporarily inhibit bacteria and remove odors, but it is difficult to maintain the health of women's vagina during menstruation during long-term use, such as the Xinghui composite core sanitary napkin and the patent document CN101579273B.

[0005] In terms of the use of sanitary napkins, existing sanitary napkins are mostly aimed at meeting menstrual hygiene needs, but ignore the fact that sanitary napkins can be used as a long-term external conditioning treatment method. For possible bacterial and viral infections of the vulva, abnormal secretions and microecological imbalances, sanitary napkins can be used as a carrier to achieve targeted and effective treatment.

[0006] As the application of Traditional Chinese Medicine (TCM) in health care continues to expand, people are increasingly embracing its natural and gentle properties. Sanitary napkins that incorporate the benefits of TCM, offering heat-clearing, dampness-removing, itching-relieving, and antibacterial properties, not only meet women's basic menstrual care needs but also provide more comprehensive protection for their physiological health. Traditional Chinese Medicine believes that dampness and heat are a key factor in many gynecological problems. Internal accumulation of dampness and heat can lead to vulvar discomfort symptoms such as thick, yellow vaginal discharge, vaginal itching, and odor. Heat-clearing and dampness-removing TCM formulas can effectively alleviate these symptoms, improve the vaginal environment during menstruation, and reduce inflammation. Furthermore, the natural and mild nature of TCM ingredients better meets women's expectations for menstrual care products, reducing the irritation and potential harm of chemicals.

[0007] In summary, it is necessary to develop a sanitary napkin containing Chinese herbal extracts for clearing heat, removing dampness and relieving itching, and protecting the health of the genitals during menstruation by combining Chinese herbal ingredients and organic phase change materials to slowly release effective ingredients, while absorbing menstrual blood and inhibiting the growth of genital bacteria, and promoting the absorption of Chinese herbal ingredients through heat release and warmth preservation by phase change materials, so as to remove dampness and relieve itching, clear away heat and inhibit bacteria. Summary of the Invention

[0008] In order to solve the above problems, the purpose of the present invention is to provide a sanitary napkin containing a Chinese herbal extract for clearing heat, removing dampness and relieving itching. The sanitary napkin achieves the functions of clearing heat, removing dampness, relieving itching and inhibiting bacteria by combining the Chinese herbal formula extract with organic phase change capsule technology. It not only focuses on short-term menstrual blood absorption and genital health, but also improves women's menstrual symptoms of heat and dampness in the long term and protects genital health during menstruation.

[0009] In order to achieve the above object, the technical solution of the present invention is as follows: a sanitary napkin containing a heat-clearing, dampness-removing and itching-relieving Chinese herbal extract, comprising a surface layer, an antibacterial absorption layer and a bottom film layer arranged in sequence from the inside to the outside,

[0010] The antibacterial absorption layer is used to absorb menstrual blood to avoid leakage and infection. The antibacterial absorption layer is sprayed with an antibacterial composition;

[0011] A sustained-release chip is fixedly connected to the center of the antibacterial absorption layer. The sustained-release chip is used to diffuse the Chinese medicine ingredients into the antibacterial absorption layer, which has the effects of removing dampness and relieving itching, clearing heat and inhibiting bacteria. The sustained-release chip contains an organic phase change capsule made of Chinese medicine concentrate.

[0012] The core principle of this basic solution lies in the synergistic effect of a multi-layered structure to achieve multifunctional effects such as clearing heat and dampness, relieving itching, and inhibiting bacteria. The top layer, acting as the medium in direct contact with the skin, ensures comfortable wearing. The antibacterial absorption layer absorbs menstrual blood. By spraying an antibacterial composition, it simultaneously absorbs menstrual blood and inhibits bacterial growth, reducing the risk of infection. The sustained-release chip is the key component for removing dampness and relieving itching. It contains a concentrated Chinese herbal solution, formulated in a scientific manner, that has the effects of removing dampness and heat, relieving itching, and inhibiting bacteria. These herbal ingredients, acting as a carrier in the organic phase-change capsules, are slowly released under suitable conditions, such as body temperature. They are absorbed through the skin and penetrate into the antibacterial absorption layer to remove dampness and reduce the impact of menstrual discharge on genital hygiene. The phase-change material in the organic phase-change capsules undergoes a phase change at body temperature, absorbing or releasing heat, acting as a thermoregulator, helping to clear heat and dampness and alleviate the discomfort caused by heat and dampness during menstruation. The bottom film layer effectively isolates external contaminants and ensures a clean interior environment for the sanitary napkin. The setting of the breathable isolation membrane further optimizes the breathability, ensures the private parts are dry, and creates a healthy physiological environment.

[0013] The beneficial effects of the basic solution are: 1. The sanitary napkin of the present invention combines multiple functions such as clearing heat and dampness, relieving itching and inhibiting bacteria, and absorbing menstrual blood. Compared with traditional sanitary napkins that only have absorption function, it provides more comprehensive care for women's menstrual health and meets women's multiple needs for health and comfort during menstruation.

[0014] 2. The antibacterial composition sprayed on the antibacterial absorption layer can effectively inhibit bacterial growth, reduce the risk of inflammation caused by bacterial infection during menstruation, and protect the health of women's private parts, especially when the immunity is relatively low during menstruation, providing an additional protective barrier.

[0015] 3. The concentrated Chinese medicine ingredients contained in the sustained-release chip can clear away heat and dampness, absorb menstrual blood, and inhibit the growth of genital bacteria and viruses, reduce the impact of vaginitis and other diseases that stimulate the vulva and produce secretions on female genital health, and improve the quality of life during menstruation.

[0016] 4. The use of organic phase change capsules achieves the slow release of Chinese medicine ingredients, prolongs the effective action time of Chinese medicine, and enables the effects of removing dampness and relieving itching to be continuously exerted, rather than being limited to short-term relief, better meeting the needs of women with longer menstrual periods.

[0017] 5. It uses traditional Chinese medicine ingredients, which are natural and mild, reducing the stimulation and potential harm of chemical substances to the human body. It meets the pursuit of modern women for natural and healthy care products and reduces the discomfort caused by material allergies and other problems.

[0018] Furthermore, the antibacterial composition includes Phellodendron amurense extract and Cnidium monnieri extract in a mass ratio of 3:1, and the spraying mass is 0.8-1.5g / m 2 .

[0019] The basic regimen offers the following benefits: 1. The antibacterial composition utilizes Phellodendron amurense extract and Cnidium monnieri extract in a precisely controlled mass ratio of 3:1. This combination leverages the antibacterial and antipruritic active ingredients of Phellodendron amurense and Cnidium monnieri extracts, resulting in a formula that alleviates vulvar itching and treats Trichomonas vaginitis. Berberine and other alkaloids contained in Phellodendron amurense extract possess significant antibacterial and anti-inflammatory properties. The synergistic effect of the two compounds with Cnidium monnieri extract significantly enhances the antibacterial effect, providing a more comprehensive defense against various bacteria that may come into contact with the vagina during menstruation and reducing the risk of infection.

[0020] 2. Set the spraying mass of the antibacterial composition to 0.8-1.5g / m 2Within this range, the antibacterial composition ensures that it forms an effective antibacterial coating on the surface of the antibacterial absorption layer, fully contacting menstrual blood and the skin of the private parts to inhibit bacterial growth, while also avoiding the problems of increased costs, waste of resources, and possible skin allergies caused by excessive use. At this spray rate, the antibacterial composition can exert its effect stably and persistently, continuously inhibiting bacteria for a long time during menstruation, and creating a healthy and safe environment for women's private parts.

[0021] Furthermore, the Chinese medicine concentrate is prepared from the following Chinese medicine raw materials in parts by weight: 10-15 parts of Kochia scoparia fruit, 5-8 parts of Pittosporum tobira bark, 10-15 parts of Sophora flavescens, 3-5 parts of Curcuma zedoaria, 3-5 parts of mint, 30-40 parts of distilled water and 80-100 parts of ethanol.

[0022] The basic regimen has the following beneficial effects: 1. The formula of this Chinese herbal concentrate has been carefully researched and formulated, encompassing a variety of Chinese medicinal raw materials with unique medicinal properties. Kochia scoparia seeds can clear away heat and dampness, dispel wind and relieve itching, alleviating vulvar itching and discomfort caused by damp heat during menstruation; Pittosporum tobira bark can dispel wind and dampness, kill insects and relieve itching, and synergistically works with Kochia scoparia seeds to further enhance the antipruritic effect and relieve local discomfort; Sophora flavescens clears heat and dampness, dispels wind and kills insects, inhibits inflammatory cell aggregation, reduces capillary permeability at the site of inflammation, reduces inflammatory exudate, and relieves inflammatory pain. It also has inhibitory effects on bacteria such as Staphylococcus aureus and hemolytic Streptococcus, as well as some fungi; Curcuma zedoaria ingredients can inhibit the release of inflammatory mediators, reduce swelling at the site of inflammation, and relieve pain, possessing antibacterial and antiviral effects; Peppermint has a cooling and detoxifying effect, dispersing nodules and relieving itching, alleviating symptoms such as headaches and breast pain caused by stagnation of Qi and blood during menstruation, while also enhancing a cooling and comfortable feeling during use. These Chinese medicinal ingredients work together to achieve multiple functions such as clearing heat and dampness, relieving itching and inhibiting bacteria, and improving immune function against viruses, providing a comprehensive conditioning and relief solution for women's menstrual inflammation problems.

[0023] 2. The weight ratios of the various Chinese medicinal ingredients are precisely controlled within a defined range, ensuring optimal synergy between them. Kochia seeds, Sophora flavescens, and Pittosporum tobira bark work together to clear heat and dampness, dispel wind, and relieve itching; Kochia seeds, Curcuma zedoaria, and Pittosporum tobira bark enhance anti-inflammatory and antibacterial effects; and peppermint provides cooling and analgesic effects. The overall formula comprehensively addresses various menstrual discomforts. This precise ratio ensures that each Chinese medicinal ingredient in the formula performs its respective functions while synergizing with each other, fully leveraging the overall strengths of the formula.

[0024] Furthermore, the Chinese medicine concentrate also includes auxiliary ingredients, and the auxiliary ingredients include 0.5-2 parts of borneol.

[0025] The beneficial effects of the basic plan are: 1. Borneol has a pungent and dispersing nature, which can open the orifices and refresh the mind, dissipate heat and relieve itching. It stimulates and guides the effects of other Chinese medicinal ingredients in the prescription, helps to improve the permeability of Chinese medicinal ingredients, and makes the effective ingredients of Chinese medicinal ingredients more easily absorbed through the skin, thereby enhancing the overall efficacy, promoting the Chinese medicinal ingredients to take effect faster, and shortening the time to relieve uncomfortable symptoms such as dysmenorrhea.

[0026] 2. While borneol has excellent benefits such as refreshing the mind, dissipating heat, and relieving itching, it is inherently irritating. Using a smaller dosage can better highlight the efficacy of other Chinese herbal ingredients. The aroma and pharmacological effects of ingredients like Kochia scoparia fruit, Pittosporum tobira bark, Sophora flavescens, and Curcuma zedoaria can be more fully expressed, preventing the strong odor of borneol from masking the properties of other ingredients. This ensures a more balanced and comprehensive efficacy of the entire Chinese herbal concentrate, leveraging the synergistic effects of each ingredient to better achieve comprehensive anti-inflammatory, antibacterial, and analgesic benefits.

[0027] Furthermore, the core material of the organic phase change capsule includes a Chinese medicine concentrate and an organic phase change material, and the mass ratio of the Chinese medicine concentrate to the organic phase change material is 1:1.

[0028] The basic solution offers the following benefits: 1. The mass ratio of TCM concentrate to organic phase change material in the organic phase change capsule core is 1:1. This ratio, scientifically verified to ensure uniform dispersion and stable encapsulation of the TCM concentrate within the phase change material, is verified by scientific experiments. During use, as the organic phase change material undergoes a phase transition under the influence of body temperature, the TCM concentrate is slowly released at a steady and sustained rate, significantly extending the duration of the drug's effectiveness. This ensures that women enjoy antipruritic and antibacterial benefits throughout their menstrual period, avoiding rapid loss of efficacy and unstable release.

[0029] 2. Organic phase change materials undergo phase changes when absorbing or releasing heat. Their phase change temperature is close to human body temperature, enabling intelligent temperature adjustment based on body temperature fluctuations. When exposed to the body's lower abdomen temperature, the phase change material absorbs heat and melts, releasing the heat and efficacy of the concentrated traditional Chinese medicine solution, providing adaptive antipruritic and antibacterial effects. Conversely, the material releases heat to prevent hypothermia, ensuring the lower abdomen remains within a suitable temperature range, promoting blood circulation, and providing a more comfortable experience for women during menstruation.

[0030] 3. Organic phase-change capsules encapsulate the TCM concentrate, effectively preventing oxidation, volatilization, and deterioration caused by environmental factors (such as air, light, and moisture) during production, storage, and use, thereby ensuring the chemical stability and biological activity of the TCM ingredients. This packaging method also reduces the risk of adverse reactions such as allergies that may occur from direct, large-area contact between the TCM concentrate and the skin, making the sanitary napkin safer and more reliable for women of all skin types.

[0031] Furthermore, the organic phase change material includes n-hexadecane and myristic acid, the mass ratio of n-hexadecane to myristic acid is 3:1, the phase change temperature after mixing is 32-36°C, and the phase change enthalpy is ≥150J / g.

[0032] The basic solution offers the following benefits: 1. A phase change enthalpy ≥ 150 J / g, indicating that the organic phase change material can store and release significant amounts of heat during the phase change process. This allows the sanitary napkin to better balance localized heat in the lower abdomen during use. When the ambient temperature is low or the lower abdomen is exposed to cold, the phase change material releases significant heat, warming the lower abdomen and promoting blood circulation. When the lower abdomen rises in temperature due to increased activity or high ambient temperatures, the phase change material absorbs heat, preventing overheating and maintaining a stable lower abdominal temperature, ensuring comfort during menstruation.

[0033] 2. The efficient phase change properties of organic phase change materials combined with concentrated TCM solutions can better promote the release of TCM ingredients. During the phase change process, the material's physical state changes provide the appropriate driving force and environment for the diffusion of the TCM concentrate, enabling a more uniform and sustained release of the TCM ingredients within the phase change temperature range, extending the duration of efficacy and improving the dehumidification and antipruritic effects.

[0034] 3. Both n-hexadecane and myristic acid are common organic phase change materials. They are stable, non-toxic, and non-irritating. The phase change process is chemically reactive, making them safe and non-irritating to the human body. Their excellent phase change properties ensure a gentle temperature change during use, eliminating the risk of discomfort or burns caused by sudden temperature changes. This further enhances the comfort and safety of the sanitary napkin, allowing women to use it with confidence during their menstrual period.

[0035] Furthermore, the organic phase change capsule wall material is a composite wall material of polylactic acid and chitosan, and the mass ratio of polylactic acid to chitosan is 2:1.

[0036] The beneficial effects of the basic solution are: 1. Polylactic acid and chitosan are both natural polymer materials with good film-forming properties. The two are compounded in a mass ratio of 2:1 to form wall materials, which can form a uniform, dense and stable capsule wall, effectively wrapping the concentrated Chinese medicine and organic phase change material to prevent leakage, volatilization or deterioration during production, storage and use, and ensure the stability and durability of the medicinal ingredients in the sanitary napkin.

[0037] 2. Polylactic acid has high mechanical strength, while chitosan has certain flexibility and extensibility. The combination of the two ensures that the capsule wall material has sufficient strength to resist external pressure and friction, preventing the capsule from breaking during use, while maintaining a certain degree of flexibility, making it suitable for the soft texture required by sanitary napkins and improving wearing comfort.

[0038] 3. Both polylactic acid and chitosan are biocompatible materials, non-toxic and harmless to the human body, and will not cause allergic reactions or other adverse reactions. Polylactic acid is a biodegradable polymer whose final metabolites are carbon dioxide and water. Chitosan has excellent antibacterial and biodegradable properties and is widely used in the pharmaceutical and food industries. Therefore, the use of this composite wall material ensures the safety and body compatibility of sanitary napkins, meeting the strict requirements of women's menstrual care products.

[0039] Furthermore, the organic phase change capsules are prepared by a multiphase emulsion method, and the release rate is increased in an acidic environment.

[0040] The basic approach offers the following benefits: 1. The organic phase-change capsules are prepared using a multiphase emulsion method, enabling them to accelerate the release of the traditional Chinese medicine concentrate and organic phase-change material in an acidic environment. The pH of the female vagina is generally weakly acidic. This preparation method allows the capsules to intelligently adjust their release rate based on the actual pH environment of the vagina after contact with the skin, ensuring timely and adequate release of the active ingredients when needed, improving drug utilization and better meeting women's needs for dehumidification, antipruritic measures, and antibacterial properties during different stages of their menstrual cycle.

[0041] 2. The capsule structure formed by the complex emulsion method is more dense and uniform, which can effectively prevent leakage, oxidation and deterioration of traditional Chinese medicine concentrate and organic phase change materials during storage and transportation, extend the shelf life of sanitary napkins, and maintain their stable performance, ensuring that the product can still play a good role when used.

[0042] 3. The characteristic of accelerated release in an acidic environment enables the active ingredients in the Chinese medicine concentrate to penetrate into the skin more quickly, improve bioavailability, enable the drug to take effect faster, relieve menstrual discomfort symptoms, and improve women's comfort and health level during menstruation.

[0043] Furthermore, a breathable isolation membrane is provided between the antibacterial absorption layer and the bottom film layer. The breathable isolation membrane is made of polylactic acid non-woven fabric with a moisture permeability of ≥500g / m 2 ·24h.

[0044] The beneficial effects of the basic solution are: 1. The breathable isolation membrane is made of polylactic acid non-woven fabric with a density of ≥500g / m 2 The 24-hour moisture permeability can effectively discharge moisture and sweat produced by the skin, keeping the private parts dry and comfortable, preventing bacteria from breeding in a humid environment, and creating a healthy physiological environment for women during menstruation.

[0045] 2. The breathable isolation membrane is set between the antibacterial absorption layer and the bottom membrane layer, which can effectively prevent the effective ingredients in the traditional Chinese medicine concentrate and the organic phase change capsule from penetrating into the outer layer of the bottom membrane, avoiding the waste of medicinal ingredients and possible pollution to clothes, while maintaining the stability and integrity of the structure of each layer of the sanitary napkin.

[0046] Furthermore, the antibacterial composition utilizes a water extraction-alcohol extraction combined process, wherein water decocting is used to extract water-soluble active ingredients, and 75% ethanol reflux is used to extract organic acids and alkaloids, thereby synergistically extracting dual-effect ingredients.

[0047] The basic solution's beneficial effect is that the combined water-alcohol extraction process allows for a more comprehensive extraction of the active ingredients in the formulated drug. Decoction yields water-soluble active ingredients, while 75% ethanol reflux extraction yields components such as organic acids and alkaloids. This ensures that the antibacterial composition is rich in active ingredients, thereby enhancing its antibacterial efficacy and pharmacological effects. BRIEF DESCRIPTION OF THE DRAWINGS

[0048] Figure 1 This is an axonometric view of a sanitary napkin containing a heat-clearing, dampness-removing and itching-relieving Chinese herbal extract according to an embodiment of the present invention.

[0049] Figure 2 This is a side cross-sectional view of a sanitary napkin containing a heat-clearing, dampness-removing and itching-relieving Chinese herbal extract according to an embodiment of the present invention.

[0050] Figure 3 Schematic diagram of the process for preparing the antibacterial composition in an embodiment of the present invention.

[0051] Figure 4 Schematic diagram of the process for preparing concentrated Chinese medicine solution in an embodiment of the present invention.

[0052] Figure 5 Schematic diagram of the process for preparing organic phase change capsules in an embodiment of the present invention.

[0053] Figure 6 The figure is a schematic diagram of the process for preparing a sanitary napkin containing a heat-clearing, dampness-removing and itching-relieving Chinese herbal extract according to an embodiment of the present invention.

[0054] The reference numerals in the drawings of the specification include: 1. surface layer; 2. antibacterial absorption layer; 3. sustained-release chip; 4. breathable isolation membrane; 5. bottom film layer. DETAILED DESCRIPTION

[0055] The following is further described in detail through specific implementation methods:

[0056] Example 1

[0057] Basically as attached Figure 1 、 Figure 2 、 Figure 3 and Figure 6As shown: A sanitary napkin containing a Chinese herbal extract for clearing heat, removing dampness and relieving itching, comprising a surface layer 1, an antibacterial absorption layer 2 and a bottom film layer 5 arranged in sequence from the inside to the outside, the antibacterial absorption layer 2 is used to absorb menstrual blood to prevent leakage and infection, and the antibacterial absorption layer 2 is sprayed with an antibacterial composition; a sustained-release chip 3 is fixedly connected to the center of the antibacterial absorption layer 2, and the sustained-release chip 3 is used to diffuse the Chinese herbal ingredients into the antibacterial absorption layer 2 to achieve the effects of removing dampness, relieving itching, clearing heat and inhibiting bacteria, and the sustained-release chip 3 contains an organic phase change capsule made of a concentrated Chinese herbal solution, and a breathable isolation membrane 4 is provided between the antibacterial absorption layer 2 and the bottom film layer 5, and the breathable isolation membrane 4 is made of polylactic acid non-woven fabric with a moisture permeability of ≥500g / m 2 ·24h.

[0058] The antibacterial composition includes Phellodendron chinense extract and Cnidium monnieri extract in a mass ratio of 3:1, and the spraying mass is 0.8-1.5g / m 2 The antibacterial composition uses a water extraction-alcohol extraction combined process, water decoction is used to extract water-soluble active ingredients, 75% ethanol reflux is used to extract organic acids and alkaloids, and dual-effect components are extracted synergistically.

[0059] The specific implementation process is as follows: Figure 2 and Figure 6 As shown, in the sanitary napkin layer structure of the present invention, the surface layer 1 is made of skin-friendly material, which can quickly guide menstrual blood, reduce skin friction, and prevent allergies; the breathable isolation membrane 4 can block the leakage interference of the drug components of the antibacterial absorption layer 2, maintain air permeability, and avoid stuffiness; the bottom film layer 5 can prevent leakage and maintain the overall structural stability of the sanitary napkin.

[0060] like Figure 3 As shown, the antibacterial composition adopts a water extraction-alcohol extraction combined process, and the specific extraction process is as follows:

[0061] 1. Experimental Materials and Equipment

[0062] Ingredients: 150g of Phellodendron chinense slices and 50g of Cnidium monnieri.

[0063] Solvent: distilled water, 75% ethanol.

[0064] Equipment: decoction pot, rotary evaporator, ultrasonic cleaning machine, freeze dryer, inhibition zone meter, HPLC.

[0065] 2. Experimental Procedure

[0066] (1) Water extraction-alcohol extraction combined process

[0067] Water extraction stage: Add 10 times the mass of distilled water to Phellodendron chinense, boil it twice at 90℃ (1.5 hours each time), combine the filtrates and concentrate to a density of 1.1g / mL.

[0068] Alcohol extraction stage: the Phellodendron chinense residue after water extraction was mixed with Cnidium monnieri, 8 times the mass of 75% ethanol was added, refluxed at 80°C for 1 hour, filtered to recover the ethanol, and concentrated to a density of 1.05g / mL.

[0069] Mixing and drying: Combine the water extract and the alcohol extract, freeze-dry them into powder, and dissolve them again in 70% ethanol before spraying.

[0070] (2) Verification of antibacterial effect

[0071] Inhibition zone assay (GB 15979-2002) for Escherichia coli and Candida albicans using the agar diffusion method, extract concentration 50 mg / mL, incubation at 37°C for 24 hours.

[0072] The minimum inhibitory concentration (MIC) method was also used for re-verification.

[0073] 3. Experimental Results

[0074] The extracted experimental data are shown in Table 1 below:

[0075] Table 1. Antibacterial composition extraction experimental data

[0076]

[0077] The combined water extraction and alcohol extraction process significantly improved the total yield, with the compound yield reaching 26.1%, while retaining the effective ingredients of Phellodendron chinense alkaloids and Cnidium monnieri, achieving synergistic extraction of dual-effect ingredients.

[0078] The diameters of the inhibition zones of the compound extract against Escherichia coli and Candida albicans were 19.8 mm and 16.6 mm, respectively, which were significantly higher than those of the single extract (p < 0.05); the MIC value against Escherichia coli was reduced to 1.56 mg / mL, and the MIC value against Candida albicans was reduced to 3.13 mg / mL, indicating that the antibacterial effect of the compound was 2-4 times that of a single component.

[0079] Experiments show that the antibacterial composition can effectively inhibit common pathogens during menstruation, and cooperates with the heat-clearing and dampness-removing functions of the sustained-release chip 3, and is suitable for regulating vaginal inflammation.

[0080] Example 2

[0081] The difference from the above embodiment is that, as shown in the attached Figure 4 As shown: The Chinese medicine concentrate is prepared from the following Chinese medicine raw materials in parts by weight: 10-15 parts of Kochia scoparia fruit, 5-8 parts of Pittosporum tobira bark, 10-15 parts of Sophora flavescens, 3-5 parts of Curcuma zedoaria, 3-5 parts of mint, 30-40 parts of distilled water and 80-100 parts of ethanol.

[0082] The Chinese medicine concentrate also comprises auxiliary components, which include 0.5-2 parts of borneol.

[0083] The specific implementation process is as follows: The preparation process of Chinese medicine concentrate is as follows:

[0084] 1. Experimental Materials and Equipment

[0085] Main ingredients: Kochia scoparia 50g, Sophora flavescens 35g, Pittosporum tobira bark 50g, Curcuma 20g and Mint 20g;

[0086] Excipients: borneol 5g;

[0087] Solvent: 200ml of distilled water, 400ml of 75% ethanol.

[0088] Equipment: decoction pot, rotary evaporator, vacuum drying oven, high performance liquid chromatography (HPLC), inhibition zone measuring instrument, constant temperature and humidity chamber.

[0089] 2. Preparation Steps (1) Segmented Extraction

[0090] Water extraction part: Mix Kochia scoparia fruit, Pittosporum tobira bark and Sophora flavescens, add distilled water, boil at 90℃ twice, each time for 2 hours, and combine the filtrates.

[0091] Alcohol extraction part: grind the Curcuma zedoaria and pass it through a 40-mesh sieve, add 75% ethanol, reflux extract at 80℃ for 1.5 hours, and filter to obtain the alcohol extract.

[0092] The volatile oil of mint was extracted by steam distillation at 60°C for 2 hours to avoid high temperature destruction of the active ingredients.

[0093] (3) Concentration and mixing

[0094] The aqueous extract was concentrated under reduced pressure at 45° C. to a density of 1.15-1.20 g / mL. The alcohol extract was concentrated to a density of 1.10-1.15 g / mL after recovering ethanol. The aqueous extract concentrate, the alcohol extract concentrate and mint volatile oil were mixed in a volume ratio of 2:1:0.5, and borneol powder was added and stirred until completely dissolved.

[0095] (4) Sterilization and packaging

[0096] The Chinese medicine concentrate was sterilized by filtering through a 0.22 μm microporous membrane, dispensed into brown glass bottles, and stored in a refrigerated place at 4°C away from light.

[0097] 3. Experimental Verification and Result Analysis

[0098] The results are shown in Table 2 below:

[0099] Table 2. Composition data of Chinese herbal medicine concentrate

[0100]

[0101] The staged extraction process, combining water and alcohol, effectively balances the effects of both water-soluble and fat-soluble active ingredients. The addition of borneol enhances the penetrability of the active ingredients in the TCM concentrate. The TCM concentrate exhibits inhibition zone diameters exceeding the standard for both Escherichia coli and Candida albicans, while maintaining a pH suitable for mucosal application. Accelerated testing demonstrates high ingredient stability, with no degradation or precipitation observed within six months.

[0102] Kochia scoparia seeds: Bitter and cold in nature, it enters the kidney and bladder meridians, promoting urination and clearing away damp heat. It is used to treat dysuria, gonorrhea, leukorrhea, hernia, rubella, sores, scabies, and genital itching.

[0103] Pittosporum bark: Bitter and neutral in nature, it enters the liver and kidney meridians, dispelling rheumatism, relaxing tendons and dredges meridians, and killing insects and relieving itching. It is used for rheumatic numbness, pain in the waist and legs, and injuries from falls; it can also be used externally to treat various stubborn ringworms.

[0104] Sophora flavescens: bitter and cold in nature, it enters the liver and kidney meridians, and has the effects of clearing heat, drying dampness, and killing insects. It is mainly used to treat dysentery caused by heat toxins, bleeding in the intestines, jaundice, leucorrhea, and external treatment of trichomonas vaginitis.

[0105] Curcuma: Pungent, bitter, and warm in nature, it enters the liver and spleen meridians, and has the effects of breaking blood and promoting qi, eliminating stagnation and relieving pain. It is mainly used to treat heart pain caused by blood and qi, food stagnation, abdominal distension and pain, blood stasis, amenorrhea, and dysmenorrhea. It also has antiviral effects.

[0106] Peppermint: It is pungent and cool in nature, and enters the lung and liver meridians. It has the effects of dispersing wind-heat, clearing the head and eyes, and promoting rashes. It is used for wind-heat colds, the initial onset of wind-heat, headaches, red eyes, throat paralysis, mouth sores, rubella, measles, and chest and flank distension.

[0107] Borneol is added later to avoid volatilization loss, and the corresponding extraction method is used to retain the active ingredients of each medicinal material to the greatest extent.

[0108] Example 3

[0109] The difference from the above embodiment is that, as shown in the attached Figure 5 and Figure 6 As shown: the core material of the organic phase change capsule includes traditional Chinese medicine concentrate and organic phase change material, and the mass ratio of the traditional Chinese medicine concentrate to the organic phase change material is 1:1.

[0110] The organic phase change material includes n-hexadecane and myristic acid, the mass ratio of n-hexadecane to myristic acid is 3:1, the phase change temperature after mixing is 32-36°C, and the phase change enthalpy is ≥150J / g.

[0111] The wall material of the organic phase change capsule is a composite wall material of polylactic acid and chitosan, with a mass ratio of polylactic acid to chitosan of 2:1. The organic phase change capsule is prepared by a multiphase emulsion method, and the release rate is improved in an acidic environment.

[0112] The specific implementation process is as follows: The preparation process of the above organic phase change capsules is as follows:

[0113] 1. Experimental Materials and Equipment

[0114] Core material: n-hexadecane (purity ≥98%), myristic acid (purity ≥95%), traditional Chinese medicine concentrate (pH 4.5).

[0115] Wall material: polylactic acid (PLA, molecular weight 10kDa), chitosan (deacetylation degree ≥90%).

[0116] Emulsifiers: Span 80, Tween 80.

[0117] Solvent: dichloromethane, 1% acetic acid solution.

[0118] Equipment: high-speed homogenizer, vacuum drying oven, freeze dryer, laser particle size analyzer, DSC differential scanning calorimeter and UV spectrophotometer.

[0119] 2. Preparation Experimental Steps

[0120] (1) Phase change material compounding

[0121] Mix n-hexadecane and myristic acid in a mass ratio of 3:1, heat to 60°C to melt, and stir until uniform.

[0122] (2) Preparation of W / O type primary emulsion

[0123] The Chinese medicine concentrate and the phase change material were mixed at a ratio of 1:1, 0.5% Span80 was added, and the mixture was homogenized at 10,000 rpm for 5 minutes to form a stable emulsion.

[0124] (3) Preparation of PLA-chitosan wall material solution

[0125] 5% PLA was dissolved in dichloromethane, and 3% chitosan was dissolved in 1% acetic acid solution. The two solutions were mixed at a volume ratio of 2:1, and 0.2% Tween 80 was added.

[0126] (4) Multiple emulsion (W / O / W type)

[0127] The core material primary emulsion was slowly added dropwise to the wall material mixed solution and homogenized at 8,000 rpm for 10 minutes to form a secondary emulsion.

[0128] (5) Solvent evaporation and curing

[0129] Stir at 40°C under vacuum conditions (-0.08 MPa) for 2 hours to volatilize dichloromethane and crosslink and solidify the wall material.

[0130] (6) Washing and drying

[0131] The capsules were collected by centrifugation at 4,000 rpm for 10 min, washed three times with deionized water, and freeze-dried for 24 h.

[0132] (7) Fixed

[0133] The organic phase change capsules are mixed with a water-based polyurethane adhesive (5% w / w), and coated in layers on the side surface of the sustained-release chip 3 close to the antibacterial absorption layer 2 .

[0134] 3. Performance Verification Results

[0135] The multiphase emulsion method successfully prepared organic phase-change capsules with uniform particle size (50-200μm) and an encapsulation efficiency of 92.3%. The process parameters are highly controllable. The phase transition temperature is 32-36°C, which precisely matches human body temperature. The 2-hour burst release rate is less than 15%, and the 24-hour cumulative release rate is greater than 80%, meeting the demand for sustained release.

[0136] The sustained-release chip 3 coated with the organic phase-change capsule has an antibacterial rate against Escherichia coli greater than 93% and a cell survival rate greater than 91%, meeting the biosafety requirements for medical materials.

[0137] After 100 thermal cycles, the phase change enthalpy retention rate is greater than 96%, indicating that the performance of the capsule is stable during long-term use.

[0138] The results are shown in Table 3 below:

[0139] Table 3. Performance verification data of organic phase change capsules

[0140]

[0141]

[0142] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that includes a list of elements includes not only those elements but also other elements not explicitly listed, or elements inherent to such process, method, article, or apparatus.

[0143] The above is only an embodiment of the present invention. Common knowledge such as the known specific structures and characteristics in the scheme is not described in detail here. Ordinary technicians in the field are aware of all common technical knowledge in the technical field of the invention before the application date or priority date, can obtain all existing technologies in the field, and have the ability to apply conventional experimental means before that date. Ordinary technicians in the field can improve and implement this scheme in combination with their own abilities under the inspiration given by this application. Some typical known structures or known methods should not become obstacles for ordinary technicians in the field to implement this application. It should be pointed out that for those skilled in the art, without departing from the structure of the present invention, several variations and improvements can be made, which should also be regarded as the scope of protection of the present invention. These will not affect the effect of the implementation of the present invention and the practicality of the patent. The scope of protection required by this application shall be based on the content of its claims, and the specific implementation methods and other records in the specification can be used to interpret the content of the claims.

Claims

1. A sanitary napkin containing a Chinese herbal extract for clearing heat, dehumidifying and relieving itching, characterized in that: It comprises a surface layer (1), an antibacterial absorption layer (2) and a bottom film layer (5) which are sequentially arranged from the inside to the outside. The antibacterial absorption layer (2) is used to absorb menstrual blood to avoid leakage and infection, and the antibacterial absorption layer (2) is sprayed with an antibacterial composition; A sustained-release chip (3) is fixedly connected to the center of the antibacterial absorption layer (2). The sustained-release chip (3) is used to diffuse the Chinese medicinal ingredients into the antibacterial absorption layer (2) to achieve the effects of removing dampness and relieving itching, clearing away heat and inhibiting bacteria. The sustained-release chip (3) contains organic phase-change microcapsules made of concentrated Chinese medicinal liquid.

2. The sanitary napkin containing the heat-clearing, dampness-removing and itching-relieving Chinese medicine extract according to claim 1, characterized in that: The antibacterial composition includes Phellodendron chinense extract and Cnidium monnieri extract in a mass ratio of 3:1, and the spraying mass is 0.8-1.5g / m 2 .

3. The sanitary napkin containing the heat-clearing, dampness-removing and itching-relieving Chinese medicine extract according to claim 1, characterized in that: The traditional Chinese medicine concentrate is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-15 parts of Kochia scoparia fruit, 5-8 parts of Pittosporum tobira bark, 10-15 parts of Sophora flavescens, 3-5 parts of Curcuma zedoaria, 3-5 parts of mint, 30-40 parts of distilled water and 80-100 parts of ethanol.

4. The sanitary napkin containing the heat-clearing, dampness-removing and itching-relieving Chinese medicine extract according to claim 3, characterized in that: The Chinese medicine concentrate also comprises auxiliary components, which include 0.5-2 parts of borneol.

5. The sanitary napkin containing the heat-clearing, dampness-removing and itching-relieving Chinese medicine extract according to claim 1, characterized in that: The core material of the organic phase change capsule includes traditional Chinese medicine concentrate and organic phase change material, and the mass ratio of the traditional Chinese medicine concentrate to the organic phase change material is 1:

1.

6. The sanitary napkin containing the heat-clearing, dampness-removing and itching-relieving Chinese medicine extract according to claim 5, characterized in that: The organic phase change material includes n-hexadecane and myristic acid, the mass ratio of n-hexadecane to myristic acid is 3:1, the phase change temperature after mixing is 32-36°C, and the phase change enthalpy is ≥150J / g.

7. The sanitary napkin containing the heat-clearing, dampness-removing and itching-relieving Chinese medicine extract according to claim 5, characterized in that: The wall material of the organic phase change capsule is a composite wall material of polylactic acid and chitosan, and the mass ratio of polylactic acid to chitosan is 2:

1.

8. The sanitary napkin containing the heat-clearing, dampness-removing and itching-relieving Chinese medicine extract according to claim 7, characterized in that: Organic phase change capsules are prepared by a multiphase emulsion method, and the release rate is increased in an acidic environment.

9. The sanitary napkin containing the heat-clearing, dampness-removing and itching-relieving Chinese herbal extract according to claim 1, characterized in that: A breathable isolation film (4) is provided between the antibacterial absorption layer (2) and the bottom film layer (5). The breathable isolation film (4) is made of polylactic acid non-woven fabric with a moisture permeability of ≥500g / m 2 ·24h.

10. The sanitary napkin containing the heat-clearing, dampness-removing and itching-relieving Chinese herbal extract according to claim 2, characterized in that: The antibacterial composition adopts a water extraction-alcohol extraction combined process, water decoction is used to extract water-soluble effective ingredients, 75% ethanol reflux is used to extract organic acids and alkaloids, and dual-effect components are extracted synergistically.

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