Composition for turning white hair into black hair and application thereof

Abstract

The invention discloses a composition for turning white hair into black hair and application of the composition. The composition for turning the white hair into the black hair is prepared from the following components in parts by mass: 1.5 to 5.0 parts of hydroxyethyl piperazine ethanesulfonic acid, 0.5 to 3.5 parts of arginine, 40.0 to 80.0 parts of glycoprotein, 24.0 to 40.0 parts of hydroxyferriheme and 0.1 to 0.6 part of vitamin C, the composition disclosed by the invention can penetrate into hair follicles to play a role, activate a plurality of MITF pathways in melanocytes in the hair follicles, induce melanin, an antioxidant and a stem cell protection factor generation receptor to react, effectively promote the function of the melanocytes, and effectively promote white hair to become black hair for a long time. Meanwhile, the composition for turning the white hair into the black hair can promote generation of fibroin of keratinocytes, scalp barrier repairing is achieved, and the combing performance of the hair and the brightness of the hair can be improved.

Description

Technical Field

[0001] The present invention relates to the technical field of daily necessities, and in particular to a composition for converting white hair into black hair and application thereof. Background Art

[0002] With the accelerated pace of life, increased work pressure, and the intensification of an aging population, premature graying of hair has become a problem that troubles many people. The graying of hair is mainly due to the decline in the function of melanocytes in the hair follicles, which cannot synthesize enough melanin, resulting in a decrease or even disappearance of melanin particles in the medulla and cortex of the hair. Currently, the easiest way to turn gray hair back to black hair is to dye the hair. Commercially available chemical hair dyes rely on oxidation reactions to cover gray hair, but they cannot repair the function of hair follicles. In addition, hair dyes usually contain aniline substances, which can easily cause scalp allergies, hair loss and other problems, and there are safety risks. Plant-based hair dyes are relatively mild, but the stability of their active ingredients is poor, and their ability to penetrate into the hair follicles is limited, so the effect of turning gray hair back to black is often not significant enough.

[0003] Hematin is an iron-containing porphyrin compound that has gradually become one of the core raw materials for hair products in recent years. Hematin can provide the necessary nutrients for the synthesis and repair of hair, repair hair, and promote melanin synthesis, as shown in the patent documents disclosed in CN118873429A and CN118141720A. However, the collection and extraction costs of the Arctic tree moss and hydrolyzed conchiolin in these patents are high, which is not conducive to industrial promotion. In addition, the mechanism of action of the combination of hematin, snakehead intestine extract and copper sulfate is unclear, and it may only superficially change the color of the hair without essentially improving the health of the hair. It cannot meet users' demand for a white-to-black product that is safe, effective, natural, and can take into account hair health care. Summary of the Invention

[0004] The main purpose of the present invention is to provide a composition for converting white hair into black hair and its application, aiming to solve the above-mentioned existing technical problems.

[0005] In order to achieve the above objectives, the first aspect of the present invention provides a composition for converting white hair into black hair, comprising the following components in parts by weight: 1.5 to 5.0 parts of hydroxyethylpiperazineethanesulfonic acid, 0.5 to 3.5 parts of arginine, 40.0 to 80.0 parts of glycoprotein, 24.0 to 40.0 parts of hydroxyhematin and 0.1 to 0.6 parts of vitamin C.

[0006] The hydroxyethylpiperazineethanesulfonic acid in the present invention can serve as both a pH regulator and a biological buffer, stabilizing the pH environment in the formulation within the range of 6.5-7.5 to protect other active ingredients in the composition from the effects of acid-base changes. It can also serve as a keratin exfoliant, softening the stratum corneum and promoting the penetration of active ingredients, thereby enhancing the bioavailability of other ingredients.

[0007] The arginine of the present invention is one of the components of hair keratin, and its content accounts for 8.8% to 9.6% of the amino acids in hair. It can provide necessary nutrition for the synthesis and repair of hair; arginine can improve the microcirculation of hair follicles, increase the blood supply in hair follicles, thereby providing more nutrients for hair, stimulating the division and proliferation of hair follicle cells, and promoting the growth of new hair.

[0008] The glycoprotein of the present invention is derived from Nicotiana benthamiana and is a granulocyte-macrophage colony-stimulating factor (GM-CSF) expressed in the plant. GM-CSF can react with melanocyte receptors in hair follicles, activate the microphthalmia-associated transcription factor pathway (MITF), and promote the secretion of R-spondin1 (RSPO1) in dermal papilla cells. This can activate hair follicles, strengthen hair, and promote the production of hair melanin.

[0009] As an antioxidant, the vitamin C of the present invention can slow the inactivation of other active ingredients in the composition, improving the overall stability of the composition. Furthermore, when applied to the scalp, vitamin C as an antioxidant can neutralize free radicals, reducing damage to the scalp caused by environmental stressors, thereby maintaining scalp health and promoting the transformation of white hair to black.

[0010] Hemoglobin has a large molecular weight, and the stratum corneum, as a skin barrier, makes it difficult for large molecular hemoglobin to effectively penetrate deep into the hair follicles. In addition, the hydroxyl group in hemoglobin is highly hydrophilic, while the surface of the hair stratum corneum is hydrophobic because it is rich in lipids and proteins, and it is generally difficult to achieve a blackening effect on the hair.

[0011] After extensive experimental research, the inventors discovered that hydroxyethylpiperazineethanesulfonic acid and hematin can synergistically enhance stratum corneum permeability and promote the transfer of melanin to the hair shaft. Furthermore, hematin can bind to keratin on the hair under the pH conditions stabilized by hydroxyethylpiperazineethanesulfonic acid, thereby enhancing dye durability. Arginine improves blood supply to hair follicles through the nitric oxide (NO) signaling pathway and, together with glycoproteins, repairs damaged hair matrix cells. Vitamin C can neutralize oxidative stress, maintain a stable environment for melanin synthesis, and prolong the activity of hematin. The hydroxyethylpiperazineethanesulfonic acid, hematin, and vitamin C in the white hair to black hair conversion composition of the present invention act synergistically, maximizing the effectiveness of hematin and continuously improving the composition's white hair to black hair conversion effect. Arginine and glycoproteins activate the melanocyte pathway in hair follicles, inducing melanin reactions and promoting the conversion of white hair to black hair and the growth of black hair.

[0012] Preferably, the composition for converting white hair to black hair comprises the following components in parts by weight: 3.16 parts of hydroxyethylpiperazineethanesulfonic acid, 1.58 parts of arginine, 63.29 parts of glycoprotein, 31.65 parts of hematin, and 0.32 parts of vitamin C. The inventors have discovered through extensive experiments that within this preferred range of parts by weight, the composition of hydroxyethylpiperazineethanesulfonic acid, arginine, glycoprotein, hematin, and vitamin C in the present invention can better exert a synergistic effect to promote melanin transfer, while also achieving the highest activity of hematin, significantly enhancing the effect of converting white hair to black.

[0013] In a second aspect, the present invention provides a method for preparing the composition for converting white hair to black hair, comprising the following steps:

[0014] The ethylpiperazineethanesulfonic acid, arginine and vitamin C are mixed evenly, and then the glycoprotein and hematin are added and mixed evenly to obtain the composition for converting white hair into black hair.

[0015] The preparation method of the composition for converting white hair into black hair of the present invention has simple operating steps. The composition comprises the following steps: firstly adding hydroxyethylpiperazineethanesulfonic acid and vitamin C to provide a stable pH environment, and then adding arginine to improve the blood supply to the hair follicles. Then, glycoprotein and hematin are added to convert white hair into black hair.

[0016] Preferably, the mixing temperature is 20-40° C., which can achieve the best mixing effect and more uniform mixing.

[0017] In a third aspect, the present invention provides the use of the composition for converting white hair to black hair in the preparation of hair products, wherein the hair products include at least one of scalp care essence, scalp care lotion, scalp nourishing cream, scalp massage cream, hair essence, hair essential oil, shampoo, shampoo soap, shampoo powder, hair mask, conditioner, hair spray, hair gel, and hair lotion. By adding the composition for converting white hair to black hair, the hair products can achieve the effect of converting white hair to black hair.

[0018] Preferably, the weight percentage of the white hair-to-black hair composition in the hair product is 0.1% to 30%. By adding the white hair-to-black hair composition of the present invention at a specific weight percentage, the prepared hair product can achieve a good white hair-to-black hair conversion effect and provide the effect of increasing hair gloss.

[0019] In a fourth aspect, the present invention provides a scalp essence comprising the composition for converting white hair into black hair, and further comprising a polyacrylate cross-linked polymer, 1,3-butylene glycol, caprylyl glycol, 1,2-hexanediol, phenoxyethanol, ethylhexylglycerin, ethoxydiglycol, sodium metasilicate, sodium citrate, and water;

[0020] Wherein, the white hair to black hair composition accounts for 0.5% to 10% by mass of the scalp essence.

[0021] Preferably, the scalp essence comprises, by mass percentage, 0.5% to 10% of the white hair to black hair composition, 0.01% to 0.1% of polyacrylate crosspolymer-6, 1% to 5% of 1,3-butylene glycol, 0.1% to 0.5% of caprylyl glycol, 0.1% to 0.5% of 1,2-hexanediol, 0.2% to 1% of phenoxyethanol, 0.01% to 0.1% of ethylhexylglycerin, 0.8% to 5% of ethoxydiglycol, 0.01% to 0.08% of sodium metasilicate, 0.001% to 0.01% of sodium citrate and the remainder of water. More preferably, the scalp essence comprises, by mass percentage, 3.16% of the white hair to black hair composition, 0.05% of polyacrylate crosspolymer-6, 3% of 1,3-butylene glycol, 0.25% of caprylyl glycol, 0.25% of 1,2-hexanediol, 0.45% of phenoxyethanol, 0.05% of ethylhexylglycerin, 2% of ethoxydiglycol, 0.039% of sodium metasilicate, 0.005% of sodium citrate and the remainder of water.

[0022] By adding the above-mentioned white hair to black hair composition in a specific mass percentage, the effects of promoting the transformation of white hair to black, improving glossiness and combing properties can be better provided.

[0023] In a fifth aspect, the present invention further provides a method for preparing the scalp essence, comprising the following steps:

[0024] (1) mixing water, polyacrylate cross-linked polymer-6, and 1,3-butanediol, heating to T1, and homogenizing to obtain a mixture 1;

[0025] (2) cooling the mixture 1 to T2, adding caprylyl glycol, 1,2-hexanediol, phenoxyethanol, and ethylhexylglycerin, and mixing uniformly to obtain a mixture 2;

[0026] (3) Cooling the mixture 2 to T3, adding ethoxydiglycol, sodium metasilicate, sodium citrate and the white hair to black hair composition, and mixing them evenly to obtain the scalp essence.

[0027] Preferably, T1 is 80-90° C., T2 is 60-70° C., and T3 is 40-50° C. Stirring at the above temperatures can quickly mix the hair evenly, and the temperature gradually decreases, which reduces the effect on the composition for converting white hair to black hair.

[0028] Preferably, the homogenization speed in step (1) is 20 to 50 Hz.

[0029] Beneficial effects:

[0030] The white hair-to-black hair conversion composition of the present invention penetrates deeply into hair follicles, activating multiple MITF pathways in melanocytes within the follicles. This activates receptors for melanin, antioxidants, and stem cell protective factors, effectively boosting melanocyte function and effectively and durably transforming white hair into black hair. Furthermore, the white hair-to-black hair conversion composition promotes the production of filaggrin in keratinocytes, repairing the scalp barrier and improving combability and brightness.

[0031] The composition for converting white hair into black hair does not contain aniline substances, is highly safe, mild and non-irritating, and can effectively solve the problem of white hair from the root of the hair follicles, significantly achieves the effect of converting white hair into black hair, and improves the health of the scalp. DETAILED DESCRIPTION

[0032] The present invention will be further described below with reference to the examples. It should be noted that the following description is intended only to explain the present invention and is not intended to limit its content. The experimental methods used in the following examples are conventional methods unless otherwise specified. The materials, reagents, etc. used in the following examples can be obtained from commercial sources unless otherwise specified.

[0033] The raw material name of the glycoprotein used in the present invention is Wisegrade TM The manufacturer is LipoTrue SL and the agent is Guangzhou Jiufeng Trading Co., Ltd.

[0034] The raw material of hematin used in the present invention is called GROWTHPHYLLIN P (PD), produced by Ichimaru Pharcos Co., Ltd., and sold by Guangzhou Jiufeng Trading Co., Ltd.

[0035] The lactoferrin used in the present invention has a product number of L302916 and is sourced from Shanghai Aladdin Biochemical Technology Co., Ltd.

[0036] The Polygonum multiflorum extract used in the present invention is from Xi'an Zhongkeda Biotechnology Co., Ltd.

[0037] Other raw materials can be purchased through regular commercial channels.

[0038] Examples 1 to 7 provide a composition for converting white hair into black hair. The contents of the components in the composition for converting white hair into black hair are shown in Table 1.

[0039] Table 1:

[0040]

[0041] The white hair-to-black hair-turning compositions of Examples 1-5 are prepared by uniformly mixing hydroxyethylpiperazineethanesulfonic acid, arginine, glycoprotein, methemoglobin, and vitamin C at 25°C to obtain the white hair-to-black hair-turning compositions. The white hair-to-black hair-turning composition of Example 6 is prepared by uniformly mixing hydroxyethylpiperazineethanesulfonic acid, arginine, glycoprotein, methemoglobin, and vitamin C at 20°C to obtain the white hair-to-black hair-turning composition. The white hair-to-black hair-turning composition of Example 7 is prepared by uniformly mixing hydroxyethylpiperazineethanesulfonic acid, arginine, glycoprotein, methemoglobin, and vitamin C at 40°C to obtain the white hair-to-black hair-turning composition.

[0042] Experimental Examples 1 to 7 provide a scalp essence. The contents of the components in the scalp essence are shown in Table 2.

[0043] Table 2:

[0044]

[0045] The preparation method of the scalp essence of Experimental Examples 1 to 5 comprises the following steps:

[0046] (1) mixing water, polyacrylate cross-linked polymer-6, and 1,3-butanediol, heating to 85° C., and homogenizing at 30 Hz to obtain a mixture 1;

[0047] (2) cooling the mixture 1 to 65° C., adding caprylyl glycol, 1,2-hexanediol, phenoxyethanol, and ethylhexylglycerin, and mixing uniformly to obtain a mixture 2;

[0048] (3) Cooling the mixture 2 to 45° C., adding ethoxydiglycol, sodium metasilicate, sodium citrate and the white hair to black hair composition, and mixing well to obtain the scalp essence.

[0049] The preparation method of the scalp essence of Experimental Example 6 comprises the following steps:

[0050] (1) Mixing water, polyacrylate cross-linked polymer-6, and 1,3-butanediol, heating to 80° C., and homogenizing at 50 Hz to obtain a mixture 1;

[0051] (2) cooling the mixture 1 to 60° C., adding caprylyl glycol, 1,2-hexanediol, phenoxyethanol, and ethylhexylglycerin, and mixing well to obtain a mixture 2;

[0052] (3) Cooling the mixture 2 to 40° C., adding ethoxydiglycol, sodium metasilicate, sodium citrate and the white hair to black hair composition, and mixing them evenly to obtain a scalp essence.

[0053] The preparation method of the scalp essence of Experimental Example 7 comprises the following steps:

[0054] (1) Mixing water, polyacrylate cross-linked polymer-6, and 1,3-butanediol, heating to 90° C., and homogenizing at 20 Hz to obtain a mixture 1;

[0055] (2) cooling the mixture 1 to 70° C., adding caprylyl glycol, 1,2-hexanediol, phenoxyethanol, and ethylhexylglycerin, and mixing well to obtain a mixture 2;

[0056] (3) Cooling the mixture 2 to 50° C., adding ethoxydiglycol, sodium metasilicate, sodium citrate and the white hair to black hair composition, and mixing them evenly to obtain a scalp essence.

[0057] Comparative Examples 1 to 5 provide a composition for converting white hair into black hair. The content of each component in the composition for converting white hair into black hair is shown in Table 3.

[0058] Table 3:

[0059]

[0060]

[0061] The preparation methods of the white hair-to-black hair conversion compositions of Comparative Examples 1-10 are the same as those of Examples 1-5.

[0062] The white hair-to-black hair compositions of Comparative Examples 1 to 10 were respectively substituted into the formula of Experimental Example 1 in Table 2, wherein the white hair-to-black hair compositions of Comparative Examples 1 to 10 replaced the white hair-to-black hair composition of Example 1 in equal amounts, and the scalp essences of Comparative Experimental Examples 1 to 10 were prepared according to the preparation methods of the scalp essences of Experimental Examples 1 to 5.

[0063] Test 1 Barrier repair test (FLG mRNA expression)

[0064] Test principle: Filaggrin (FLG) is an important structural protein in the stratum corneum. During the epidermal differentiation process, FLG is further broken down into free amino acids by Caspase14 protein, and subsequently further broken down to produce natural moisturizing factor (NMF), which helps to maintain skin moisture. It also participates in the terminal differentiation of keratinocytes and plays a key role in maintaining the integrity of the epidermal barrier. When the expression level of the FLG gene decreases, it will lead to a decrease in filaggrin synthesis, which in turn leads to a decrease in the hydration capacity of the stratum corneum, an increase in transepidermal water loss (TEWL) and defective barrier function. In addition, FLG can bind to keratin intermediate filaments, promote keratinocyte differentiation and the formation of the corneous envelope (CE). CE is a cross-linked structure on the inner side of the keratinocyte membrane. It is cross-linked with endothelial proteins, loricrin, etc. through the action of transglutaminase, thereby enhancing the mechanical strength and resistance to external stimuli of keratinocytes. Therefore, the barrier repair effect of the test sample can be evaluated by the expression level of the filaggrin gene in keratinocytes.

[0065] Test sample: the composition for converting white hair into black hair of Examples 1 to 7 and Comparative Examples 1 to 10, diluted with DMEM culture medium to form a solution with a mass concentration of 2%.

[0066] Test steps: HaCaT cells in logarithmic phase were inoculated into culture flasks, and HaCaT cells grown to 90% were collected and counted. The cell suspension was diluted with DMEM medium (hereinafter referred to as medium) and the cell count was 2.0×10 6 Cells were inoculated into 6-well plates and placed in a 37°C, 5% CO2 incubator for 24 hours. After the culture was completed, the culture medium was aspirated and discarded, and the cells were rinsed three times with D'Hanks. 1 mL of D'Hanks was added, and the model control group and the test sample group were irradiated with UVB for modeling, and the negative control group was placed in the dark for the same period of time. After modeling, 1 mL of culture medium was added to the model control group and the negative control group, and 1 mL of the corresponding test sample was added to the test sample group. The cells were cultured in a 37°C, 5% CO2 incubator for 24 hours. After the culture was completed, the cells in each group were broken and RNA was collected, and reverse transcription was performed for fluorescence quantitative PCR. Real-time fluorescence quantitative results were obtained using 2 －△△CTThe relative expression of FLG mRNA in the negative control group was calculated as 1.00. Three replicates were run for each group, and the average of the test results was taken. The test results are shown in Table 4.

[0067] Table 4:

[0068] Group Relative expression of FLG mRNA Group Relative expression of FLG mRNA Negative control group 1.00 Comparative Example 1 1.04 Model control group 0.68 Comparative Example 2 1.01 Example 1 1.42 Comparative Example 3 0.82 Example 2 1.46 Comparative Example 4 0.91 Example 3 1.58 Comparative Example 5 0.96 Example 4 1.52 Comparative Example 6 1.24 Example 5 1.38 Comparative Example 7 1.18 Example 6 1.35 Comparative Example 8 1.02 Example 7 1.30 Comparative Example 9 0.98 / / Comparative Example 10 1.19

[0069] The test results show that: compared with the negative control group, the expression level of the FLG gene in HaCaT cells decreased after UVB irradiation (model control group), and after the addition of the test sample, the expression level of the FLG gene in HaCaT cells increased compared with the model control group. This shows that the test sample can promote the expression of the FLG gene in the cells, showing a barrier repair effect. The expression level of the FLG gene in Examples 1 to 7 is higher than that in Comparative Examples 1 to 10, and even higher than that in the negative control group. Among them, the expression level of the FLG gene in Examples 1 to 7 is higher than that in Comparative Examples 1 to 5, indicating that in the white hair to black hair composition of the present invention, there is a synergistic effect between hydroxyethylpiperazineethanesulfonic acid, arginine, glycoprotein, hydroxyferrous hematin and vitamin C. The five active components work together to achieve a better barrier repair effect. Without one of the components, the barrier repair effect of the composition deteriorates. The expression levels of the FLG gene in Examples 1 to 7 were higher than those in Comparative Examples 6 to 10, indicating that replacing any component of hydroxyethylpiperazineethanesulfonic acid, arginine, glycoprotein, hematin, and vitamin C with a component with similar functions to form a new white hair-to-black hair composition still had a worse barrier repair effect than the white hair-to-black hair composition of Examples 1 to 7. This further indicates that the synergistic effect between the five components of hydroxyethylpiperazineethanesulfonic acid, arginine, glycoprotein, hematin, and vitamin C is stronger, resulting in a better barrier repair effect of the white hair-to-black hair composition.

[0070] Test Example 2: Hair turning from white to black

[0071] Test samples: scalp essences of Experimental Examples 1 to 7, scalp essences of Comparative Experimental Examples 1 to 10, and matrix essences (the components and preparation methods are the same as those of Experimental Example 1, except that the white hair to black hair composition is replaced with deionized water of the same mass percentage).

[0072] Test steps: 90 healthy male and female subjects aged 40 to 55 years old (with more than 25% of gray hair) were selected and randomly divided into 18 groups, with 5 people in each group. Each group used a scalp serum (including matrix serum). The usage method was to use the test sample every day before bed, apply approximately 3mL to the entire scalp, apply and massage the product, and use the test sample for 4 weeks.

[0073] Before applying the test sample, the subjects shaved 1.8 cm2 The target area was treated. A digital photograph of the shaved area was taken using a dermatoscope (Dermogenius, Dermoscan). Two days after shaving, the percentage of gray hair in the total hair was assessed. After applying the test sample, the corresponding hair of the subject was treated identically and the percentage of gray hair in the total hair was assessed. The change in the percentage of gray hair before and after application of the test sample was calculated to evaluate the effectiveness of the scalp serum in transforming gray hair to darker hair.

[0074] Change rate of white hair ratio (%) = (white hair ratio after using the test sample - white hair ratio before using the test sample) / white hair ratio before using the test sample × 100%.

[0075] Please refer to Table 5 for the test results.

[0076] Test Example 3: Hair Glossiness Test

[0077] Test samples: scalp essences of Experimental Examples 1 to 7, scalp essences of Comparative Experimental Examples 1 to 10, and matrix essences (the components and preparation methods are the same as those of Experimental Example 1, except that the white hair to black hair composition is replaced with deionized water of the same mass percentage).

[0078] Test steps: 90 healthy male and female subjects aged 40 to 55 years old (with more than 25% of gray hair) were selected and randomly divided into 18 groups, with 5 people in each group. Each group used a scalp serum (including matrix serum). The usage method was to use the test sample every day before bed, apply approximately 3mL to the entire scalp, apply and massage the product, and use the test sample for 4 weeks.

[0079] Before and after application of the test sample, hair color brightness and glossiness were measured using a colorimeter CM-700d (Konica Minolta). Measurement parameters: 8° gloss was used to measure hair gloss. The rate of change in hair gloss was calculated and used to evaluate the brightening effect of the scalp serum.

[0080] Hair glossiness change rate (%) = (hair glossiness after using the test sample - hair glossiness before using the test sample) / hair glossiness before using the test sample × 100%.

[0081] Please refer to Table 5 for the test results.

[0082] Test Example 4 Hair Combing Test

[0083] Test samples: scalp essences of Experimental Examples 1 to 7, scalp essences of Comparative Experimental Examples 1 to 10, and base essences (same as Test Examples 2 to 3).

[0084] Test Procedure: Prepare 90 test tresses (cylindrical tresses, specifications: net weight: 8g, length: 25cm, 5 tresses per test sample). Before using the sample, comb the naturally dried, unused tresses, comb them once forwards and once backwards, then clamp them on a test clip for the dry combing performance test. Repeat the test five times and average the results. Apply 1mL of the test sample to the hair surface and evenly spread it. Hang the tresses and let them air dry overnight at room temperature. Comb the tresses, comb them once forwards and once backwards, then clamp them on a test clip for the dry combing performance test. Repeat the test five times and average the results. The change in combing performance before and after the sample application is measured to evaluate the smoothing effect of the scalp serum on hair.

[0085] Hair tress combing work change rate (%) = (dry hair tress combing work after using the sample - dry hair tress combing work before using the sample) - dry hair tress combing work before using the sample × 100%.

[0086] The test results are shown in Table 5.

[0087] Table 5:

[0088]

[0089]

[0090] The above data demonstrates that, compared to the base serum and the scalp serums of Comparative Experimental Examples 1-10, the scalp serum containing the white hair-to-black hair composition of the present invention significantly improved the glossiness of the subjects' hair, significantly reduced the percentage of white hair, and improved combability. This demonstrates that the white hair-to-black hair composition of the present invention, when applied to a scalp serum, significantly achieves the effects of turning white hair black, nourishing hair, and improving hair smoothness. Furthermore, the white hair-to-black hair composition of Example 3 exhibits the best results, and the most effective when applied to a scalp serum.

[0091] The above description is only a preferred embodiment of the present invention and does not limit the patent scope of the present invention. Any equivalent structure or equivalent process transformation made using the contents of the present invention specification, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of the present invention.

Claims

1. A composition for converting white hair into black hair, characterized in that: The invention comprises the following components in parts by mass: 1.5 to 5.0 parts of hydroxyethylpiperazineethanesulfonic acid, 0.5 to 3.5 parts of arginine, 40.0 to 80.0 parts of glycoprotein, 24.0 to 40.0 parts of hematin and 0.1 to 0.6 part of vitamin C.

2. The composition for converting white hair to black hair according to claim 1, wherein The invention comprises the following components in parts by mass: 3.16 parts of hydroxyethylpiperazineethanesulfonic acid, 1.58 parts of arginine, 63.29 parts of glycoprotein, 31.65 parts of hematin and 0.32 parts of vitamin C.

3. A method for preparing the composition for converting white hair to black hair according to claim 1 or 2, characterized in that: The following steps are involved: The ethylpiperazineethanesulfonic acid, arginine and vitamin C are mixed evenly, and then the glycoprotein and hematin are added and mixed evenly to obtain a composition for converting white hair into black hair.

4. Use of the composition for converting white hair to black hair according to claim 1 or 2 in preparing a hair product, wherein the hair product comprises at least one of a scalp care essence, a scalp care lotion, a scalp nourishing cream, a scalp massage cream, a hair essence, a hair essential oil, a shampoo, a shampoo soap, a shampoo powder, a hair mask, a hair conditioner, a hair spray, a hair gel, and a hair lotion.

5. The use according to claim 4, characterized in that The mass percentage of the white hair to black hair composition in the hair product is 0.1% to 30%.

6. A scalp essence, characterized in that: The composition for converting white hair into black hair according to any one of claims 1 to 2, further comprising polyacrylate cross-linked polymer, 1,3-butylene glycol, caprylyl glycol, 1,2-hexanediol, phenoxyethanol, ethylhexylglycerin, ethoxydiglycol, sodium metasilicate, sodium citrate and water; Wherein, the white hair to black hair composition accounts for 0.5% to 10% by mass of the scalp essence.

7. The scalp essence according to claim 6, characterized in that The scalp essence comprises, by mass percentage, 0.5% to 10% of a composition for converting white hair into black hair, 0.01% to 0.1% of polyacrylate cross-polymer-6, 1% to 5% of 1,3-butylene glycol, 0.1% to 0.5% of caprylyl glycol, 0.1% to 0.5% of 1,2-hexanediol, 0.2% to 1% of phenoxyethanol, 0.01% to 0.1% of ethylhexylglycerin, 0.8% to 5% of ethoxydiglycol, 0.01% to 0.08% of sodium metasilicate, 0.001% to 0.01% of sodium citrate, and the balance of water.

8. The scalp essence according to claim 7, characterized in that The scalp essence includes, by mass percentage, 3.16% of a white hair to black hair conversion composition, 0.05% of polyacrylate crosspolymer-6, 3% of 1,3-butylene glycol, 0.25% of caprylyl glycol, 0.25% of 1,2-hexanediol, 0.45% of phenoxyethanol, 0.05% of ethylhexylglycerin, 2% of ethoxydiglycol, 0.039% of sodium metasilicate, 0.005% of sodium citrate, and the balance of water.

9. A method for preparing the scalp essence according to any one of claims 6 to 8, characterized in that: The following steps are involved: (1) mixing water, polyacrylate cross-linked polymer-6, and 1,3-butanediol, heating to T1, and homogenizing to obtain a mixture 1; (2) cooling the mixture 1 to T2, adding caprylyl glycol, 1,2-hexanediol, phenoxyethanol, and ethylhexylglycerin, and mixing uniformly to obtain a mixture 2; (3) Cooling the mixture 2 to T3, adding ethoxydiglycol, sodium metasilicate, sodium citrate and the white hair to black hair composition, and mixing well to obtain the scalp essence.

10. The method for preparing the scalp essence according to claim 9, characterized in that: The T1 is 80-90°C; the T2 is 60-70°C; and the T3 is 40-50°C.

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