Traditional Chinese medicine compound preparation for treating constipation and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine compound preparation for treating constipation and a preparation method of the traditional Chinese medicine compound preparation. The traditional Chinese medicine compound preparation is prepared from 20-90 g of radix astragali, 10-60 g of raw rhizoma atractylodis macrocephalae, 10-15 g of peach kernels, 30-60 g of fructus cannabis, 30-45 g of herba leonuri, 6-60 g of raw radix et rhizoma rhei, 30-60 g of fried fructus aurantii immaturus, 15-30 g of ginger processed cortex magnoliae officinalis, 15-20 g of pogostemon cablin, 15-30 g of fried betel nuts, 10-30 g of fried semen raphani, 3-6 g of stevia rebaudiana leaves, 3-10 g of agilawood, 15-30 g of pericarpium citri reticulatae and 10-15 g of radix aucklandiae. The traditional Chinese medicine compound preparation disclosed by the invention has the beneficial effect of comprehensively treating constipation through compatibility of various medicinal materials. Firstly, radix astragali has the effects of enhancing immunity and regulating spleen and stomach functions, and can improve intestinal tract movement and promote digestion and absorption of food; and the raw bighead atractylodes rhizome has the effects of invigorating spleen and replenishing qi, can regulate the transportation and transformation functions of spleen and stomach, and is beneficial to improving the root cause of constipation. The peach kernels and the fructus cannabis have the effect of relaxing bowel, and can promote peristalsis of intestinal tracts.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine compound preparation for treating constipation and a preparation method thereof. BACKGROUND

[0002] Constipation is a common digestive problem that affects a large number of adults and the elderly, and long-term ineffective relief can lead to a series of health problems such as abdominal distension, loss of appetite, etc., and can even cause other digestive diseases. Therefore, developing a traditional Chinese medicine compound preparation with significant efficacy is an important requirement for the current clinical treatment of constipation. This prescription selects a variety of traditional Chinese medicinal materials such as Huangqi, Shengbaishu, Taoren, Huomaren, etc., combined with modern pharmacological research, has the effects of regulating the spleen and stomach, promoting blood circulation to unblock the bowels, and moistening the intestines. Through scientific compatibility, these medicinal materials can synergize with each other to form a unique efficacy advantage, which can ensure efficacy while avoiding side effects that may occur when a single drug is used. The core goal of this project is to verify the effectiveness of the compound preparation in relieving constipation and improving intestinal function through clinical trials, provide a new treatment plan for constipation, and promote the widespread application of traditional Chinese medicine in modern clinical practice, providing safer and more effective treatment options for patients with constipation. SUMMARY

[0003] The present application relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine compound preparation for treating constipation and a preparation method thereof.

[0004] To achieve the above-mentioned object, the technical scheme of the present application is as follows: a traditional Chinese medicine compound preparation for treating constipation and a preparation method thereof, the traditional Chinese medicine compound preparation for treating constipation comprises Huangqi 20-90g, Shengbaishu 10-60g, Taoren 10-15g, Huomaren 30-60g, Yimucao 30-45g, Shengdahuang 6-60g, Chaozhishi 30-60g, Jianghoupu 15-30g, Guanghuoxiang 15-20g, Chaobinglang 15-30g, Chaolaifuzi 10-30g, Tianyekujyleaf 3-6g, Chenxi 15-30g, Muxiang 10-15g.

[0005] The preparation method of the traditional Chinese medicine compound preparation, characterized in that it comprises the following steps: S1: raw material preparation: Huangqi, Shengbaishu, Taoren, Huomaren, Yimucao, Shengdahuang, Chaozhishi, Jianghoupu, Guanghuoxiang, Chaobinglang, Chaolaifuzi, Tianyekujyleaf, Chenxi, Muxiang, etc. are weighed according to the formula ratio to ensure accuracy.

[0006] S2: cleaning and processing: All medicinal materials are cleaned and processed, especially those that are easy to attach impurities such as Taoren and Huomaren, which need to be carefully cleaned. If necessary, the medicinal materials are cut or crushed to ensure uniform extraction.

[0007] S3: Processing of medicinal materials: Radix Astragali: Lightly roasted to make its efficacy more easily released.

[0008] Raw Atractylodes Rhizome: Lightly roasted as needed or used directly.

[0009] Semen Persicae: Can be used directly after peeling.

[0010] Cannabis Sativa, Motherwort, Fried Citrus Aurantium, Ginger and Magnolia Officinalis, Pogostemonis Herba, Fried Semen Arecae, Fried Semen Raphani, Pericarpium Citri Reticulatae, and Aquilaria Agallocha: Can be properly processed according to traditional methods, such as frying and calcining, especially for medicinal materials that promote bowel movements and regulate the stomach and intestines.

[0011] S4: Compatibility extraction: Put the processed medicinal materials and an appropriate amount of water into the extraction equipment, use appropriate water temperature and extraction time (for example, 80°C-90°C water extraction for 30 minutes), and decoct. The extraction process can be divided into two times to ensure the full release of the efficacy.

[0012] S5: Filtration and concentration: Filter the extraction liquid to remove the dregs, and collect the medicinal liquid. Concentrate the medicinal liquid, control the concentration ratio, and ensure that the final product concentration meets the specification requirements.

[0013] S6: Drying to make powder or preparation: Powder preparation: Spray dry or freeze-dry the concentrated liquid to obtain dried traditional Chinese medicine powder.

[0014] Granular preparation: The dried powder can also be mixed with excipients to make granules for easy consumption.

[0015] Further, the Radix Astragali is 50 grams.

[0016] Further, the raw Atractylodes Rhizome is 40 grams.

[0017] Further, the Cannabis Sativa is 40 grams.

[0018] Further, the Motherwort is 40 grams.

[0019] Further, the Fried Citrus Aurantium is 40 grams.

[0020] Further, the Ginger and Magnolia Officinalis is 20 grams.

[0021] Further, the Aquilaria Agallocha is 6 grams.

[0022] Further, the Aquilaria Agallocha is 6 grams.

[0023] The application discloses a traditional Chinese medicine compound preparation for treating constipation and a preparation method thereof. The traditional Chinese medicine compound preparation is prepared by mixing multiple medicinal materials, and has the beneficial effect of comprehensively treating constipation. First, the astragalus membranaceus has the effects of enhancing immunity and regulating the functions of the spleen and stomach, and can improve intestinal peristalsis and promote food digestion and absorption. The raw atractylodes rhizome has the effects of invigorating the spleen and benefiting qi, and can regulate the transportation and transformation functions of the spleen and stomach, and help improve the root cause of constipation. The persicae semen and cannabis sativa seeds have the effects of moistening the intestines and promoting defecation, and can promote intestinal peristalsis, soften stool and relieve constipation symptoms. The motherwort, fried citrus aurantium, ginger and magnolia officinalis further play the roles of promoting blood circulation and regulating qi, so that the intestinal function is more coordinated, and the repeated occurrence of constipation is avoided. The fried terminalia chebula, fried raphanus seeds and other medicinal materials can increase the excretion capacity of the intestines and enhance the treatment effect of constipation. Meanwhile, the stevia rebaudiana has the effects of regulating intestinal microflora and promoting intestinal peristalsis, and the linaloe and dried tangerine or orange peel have the functions of regulating qi and regulating stomach qi, and help improve the constipation problem caused by intestinal qi stagnation. Through the synergistic effect of multiple medicinal materials, the compound preparation can not only improve the symptoms of constipation, but also regulate the functions of the spleen and stomach and promote intestinal health, and has high clinical application value. The traditional Chinese medicine preparation can help constipation patients obtain long-term relief, and due to the comprehensive effect of multiple components, the side effects caused by single treatment method can be effectively avoided. DETAILED DESCRIPTION

[0024] The application will be specifically described below. The application discloses a traditional Chinese medicine compound preparation for treating constipation and a preparation method thereof.

[0025] Embodiment 1 The application discloses a traditional Chinese medicine compound preparation for treating constipation and a preparation method thereof. The traditional Chinese medicine compound preparation is prepared by mixing multiple medicinal materials, and has the beneficial effect of comprehensively treating constipation. First, the astragalus membranaceus has the effects of enhancing immunity and regulating the functions of the spleen and stomach, and can improve intestinal peristalsis and promote food digestion and absorption. The raw atractylodes rhizome has the effects of invigorating the spleen and benefiting qi, and can regulate the transportation and transformation functions of the spleen and stomach, and help improve the root cause of constipation. The persicae semen and cannabis sativa seeds have the effects of moistening the intestines and promoting defecation, and can promote intestinal peristalsis, soften stool and relieve constipation symptoms. The motherwort, fried citrus aurantium, ginger and magnolia officinalis further play the roles of promoting blood circulation and regulating qi, so that the intestinal function is more coordinated, and the repeated occurrence of constipation is avoided. The fried terminalia chebula, fried raphanus seeds and other medicinal materials can increase the excretion capacity of the intestines and enhance the treatment effect of constipation. Meanwhile, the stevia rebaudiana has the effects of regulating intestinal microflora and promoting intestinal peristalsis, and the linaloe and dried tangerine or orange peel have the functions of regulating qi and regulating stomach qi, and help improve the constipation problem caused by intestinal qi stagnation. Through the synergistic effect of multiple medicinal materials, the compound preparation can not only improve the symptoms of constipation, but also regulate the functions of the spleen and stomach and promote intestinal health, and has high clinical application value. The traditional Chinese medicine preparation can help constipation patients obtain long-term relief, and due to the comprehensive effect of multiple components, the side effects caused by single treatment method can be effectively avoided.

[0026] Embodiment 2 The application discloses a traditional Chinese medicine compound preparation for treating constipation and a preparation method thereof. The traditional Chinese medicine compound preparation is prepared by mixing multiple medicinal materials, and has the beneficial effect of comprehensively treating constipation. First, the astragalus membranaceus has the effects of enhancing immunity and regulating the functions of the spleen and stomach, and can improve intestinal peristalsis and promote food digestion and absorption. The raw atractylodes rhizome has the effects of invigorating the spleen and benefiting qi, and can regulate the transportation and transformation functions of the spleen and stomach, and help improve the root cause of constipation. The persicae semen and cannabis sativa seeds have the effects of moistening the intestines and promoting defecation, and can promote intestinal peristalsis, soften stool and relieve constipation symptoms. The motherwort, fried citrus aurantium, ginger and magnolia officinalis further play the roles of promoting blood circulation and regulating qi, so that the intestinal function is more coordinated, and the repeated occurrence of constipation is avoided. The fried terminalia chebula, fried raphanus seeds and other medicinal materials can increase the excretion capacity of the intestines and enhance the treatment effect of constipation. Meanwhile, the stevia rebaudiana has the effects of regulating intestinal microflora and promoting intestinal peristalsis, and the linaloe and dried tangerine or orange peel have the functions of regulating qi and regulating stomach qi, and help improve the constipation problem caused by intestinal qi stagnation. Through the synergistic effect of multiple medicinal materials, the compound preparation can not only improve the symptoms of constipation, but also regulate the functions of the spleen and stomach and promote intestinal health, and has high clinical application value. The traditional Chinese medicine preparation can help constipation patients obtain long-term relief, and due to the comprehensive effect of multiple components, the side effects caused by single treatment method can be effectively avoided. S1: raw material preparation The astragalus membranaceus, raw atractylodes rhizome, persicae semen, cannabis sativa seeds, motherwort, raw rhubarb, fried citrus aurantium, ginger and magnolia officinalis, broadleaf chenopodium, fried terminalia chebula, fried raphanus seeds, stevia rebaudiana leaves, linaloe and dried tangerine or orange peel, and zedoary are weighed according to the prescription ratio to ensure accuracy.

[0027] S2: cleaning and processing All medicinal materials need to be cleaned, especially those that are prone to attach impurities, such as peach kernel and hemp seed. If necessary, the medicinal materials can be cut or crushed to ensure uniform extraction.

[0028] S3: Processing of medicinal materials: Radix Astragali: Lightly roasted to make its efficacy more easily released.

[0029] Raw Atractylodes: Lightly roasted or used directly as needed.

[0030] Peach kernel: Can be used directly after peeling.

[0031] Hemp seed, Motherwort, Fried Citrus aurantium, Ginger and Magnolia officinalis, Agastache rugosa, Fried Semen Arecae, Fried Semen Raphani, Pericarpium Citri Reticulatae, and Aquilaria sinensis: Can be properly processed according to traditional methods, such as frying and calcining, especially for medicinal materials that promote bowel movements and regulate the stomach and intestines.

[0032] S4: Compatibility extraction: Put the processed medicinal materials and an appropriate amount of water into the extraction equipment, use appropriate water temperature and extraction time (e.g., 80°C-90°C water extraction for 30 minutes), and decoct. The extraction process can be divided into two times to ensure the full release of efficacy.

[0033] S5: Filtration and concentration: Filter the extraction liquid to remove the dregs, and collect the medicinal liquid. Concentrate the medicinal liquid, control the concentration ratio, and ensure that the final product concentration meets the specification requirements.

[0034] S6: Drying to make powder or preparation: Powder preparation: Spray dry or freeze-dry the concentrated liquid to obtain dried traditional Chinese medicine powder.

[0035] Granular preparation: The dried powder can also be mixed with excipients to make granules for easy consumption.

[0036] Further, the Radix Astragali is 50 grams.

[0037] Further, the raw Atractylodes is 40 grams.

[0038] Further, the hemp seed is 40 grams.

[0039] Further, the Motherwort is 40 grams.

[0040] Further, the Fried Citrus aurantium is 40 grams.

[0041] Further, the ginger and Magnolia officinalis are 20 grams.

[0042] Further, the Aquilaria sinensis is 6 grams.

[0043] Further, the Aquilaria sinensis is 6 grams.

[0044] The above technical solution only embodies the preferred technical solution of the present application, and some changes made by the person skilled in the art to some parts of the present application embody the principle of the present application and are within the protection scope of the present application.

Claims

1. A Chinese medicinal compound preparation for treating constipation, characterized in that: It includes 20-90 grams of astragalus, 10-60 grams of raw white atractylodes, 10-15 grams of peach kernel, 30-60 grams of hemp seed, 30-45 grams of motherwort, 6-60 grams of raw rhubarb, 30-60 grams of fried Citrus aurantium, 15-30 grams of Magnolia officinalis, 15-20 grams of patchouli, 15-30 grams of fried betel nut, 10-30 grams of fried radish seeds, 3-6 grams of stevia leaves, 3-10 grams of agarwood, 15-30 grams of dried tangerine peel, and 10-15 grams of costus root.

2. The method for preparing the Chinese medicinal compound preparation according to claim 1, wherein The following steps are involved: S1: Raw material preparation: Weigh astragalus, raw white atractylodes, peach kernel, hemp seed, motherwort, raw rhubarb, stir-fried immature bitter orange, ginger magnolia bark, patchouli, stir-fried betel nut, stir-fried radish seed, stevia leaf, agarwood, tangerine peel, costus root and other medicinal materials according to the formula ratio to ensure accuracy; S2: Cleaning and processing: All medicinal materials should be cleaned, especially those that are prone to impurities such as peach kernels and hemp kernels. If necessary, the medicinal materials should be properly cut or crushed to ensure uniform extraction. S3: Preparation of medicinal materials: Astragalus: Lightly stir-fry to release its medicinal properties more easily; Raw Atractylodes macrocephala: lightly stir-fry as needed or use directly; Peach kernel: can be used directly after peeling; Hemp seed, motherwort, stir-fried immature bitter orange, ginger magnolia bark, patchouli, stir-fried betel nut, stir-fried radish seed, tangerine peel, costus root, etc.: they can be properly prepared according to traditional methods, such as stir-frying or calcining, especially for herbs that promote laxative effects and regulate the stomach; S4: Compatible extraction: Place the processed herbs with an appropriate amount of water into the extraction equipment and boil them at an appropriate water temperature and extraction time (e.g., 80°C-90°C for 30 minutes). The extraction process can be divided into two steps to ensure the full release of the medicinal properties. S5: Filtration and concentration: The extract is filtered to remove the drug residue and the drug solution is collected. The drug solution is concentrated and the concentration ratio is controlled to ensure that the final product concentration meets the specification requirements; S6: Drying to make powder or preparation: Powder preparation: The concentrated liquid is spray-dried or freeze-dried to obtain dry Chinese medicine powder; Granular preparation: The dried powder can also be mixed with excipients to make granules for easy administration.

3. A Chinese medicinal compound preparation for treating constipation according to claim 1, characterized in that: 50 grams of the astragalus root.

4. A Chinese medicinal compound preparation for treating constipation according to claim 1, characterized in that: 40 grams of the raw Atractylodes macrocephala.

5. A Chinese medicinal compound preparation for treating constipation according to claim 1, characterized in that: 40 grams of hemp seeds.

6. A Chinese medicinal compound preparation for treating constipation according to claim 1, characterized in that: 40 grams of the motherwort.

7. A Chinese medicinal compound preparation for treating constipation according to claim 1, characterized in that: 40 grams of the stir-fried Citrus aurantium.

8. A Chinese medicinal compound preparation for treating constipation according to claim 1, characterized in that: 20 grams of the ginger magnolia bark.

9. A Chinese medicinal compound preparation for treating constipation according to claim 1, characterized in that: The agarwood is 6 grams.

10. A Chinese medicinal compound preparation for treating constipation according to claim 1, characterized in that: The costus root is 12 grams.