Method for preparing an active layer and apparatus comprising the active layer
CN120813340APending Publication Date: 2025-10-17TULIP MEDICAL LTD
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Patent Information
- Application Number
- CN202480011133.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Priority Date
- 2023-02-08
- Filing Date
- 2024-02-06
- Publication Date
- 2025-10-17
AI Technical Summary
Technical Problem
The prior art has difficulty in effectively dispersing mucoadhesive compositions on tissue surfaces and maintaining adhesion for a sufficient time, resulting in low active agent delivery efficiency.
Method used
By mixing the mucoadhesive material with the active agent into a slurry and using a non-aqueous solvent to form a particulate active layer, it is ensured that the mucoadhesive material remains in particulate form in the active layer until activated for adhesion after deployment at the target site.
Benefits of technology
The mucosal adhesive material is quickly activated and adhered to the target site, thereby improving the delivery efficiency and adhesion effect of the active agent.
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Smart Images
Figure CN120813340A_ABST
Abstract
The present disclosure relates to methods for preparing an active layer, typically a layer comprising a mucoadhesive material and one or more pharmaceutically active compounds or nutrients, and devices comprising such active layers. The method is designed to maintain the mucoadhesive material in a non-activated form during the preparation of the active layer and to allow the mucoadhesive material to be activated once near the target site.
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