10% spinosad tolfenpyrad suspending agent and preparation method thereof

Abstract

The invention belongs to the field of pesticides, and particularly relates to a 10% spinosad tolfenpyrad suspending agent and a preparation method thereof. The 10% spinosad-tolfenpyrad suspending agent is prepared from the following raw materials in parts by mass: 5 to 20 parts of raw pesticide, 1 to 10 parts of a dispersing agent, 1 to 10 parts of an anti-freezing agent, 1 to 20 parts of a thickening agent, 0.1 to 1 part of a preservative, 0.1 to 1 part of a de-foaming agent and 50 to 100 parts of de-ionized water. Wherein the pesticide raw materials comprise spinosad active compound and tolfenpyrad active compound, and the dispersing agent comprises a polycarboxylate wetting dispersing agent, a naphthalene sulfonate wetting dispersing agent and a block polyether emulsifying dispersing agent. According to the invention, through screening of the raw medicines and the dispersing agent, the prepared suspending agent is high in stability and excellent in insecticidal effect.

Description

TECHNICAL FIELD

[0001] The present application belongs to the field of pesticides, and particularly relates to a 10% spinosad·flubrocythrinate suspension agent and a preparation method thereof. BACKGROUND

[0002] In actual agricultural production, the use of spinosad or flubrocythrinate suspension agent alone has limitations in preventing and treating Frankliniella occidentalis on eggplant. For example, 10% spinosad suspension agent or 15% flubrocythrinate suspension agent cannot fully exert the synergistic effect of the two and effectively control the damage of Frankliniella occidentalis. At present, the problem of Frankliniella occidentalis is usually solved by using spinosad and flubrocythrinate in combination. For example, Chinese Patent Application CN101669476A discloses a synergistic pesticide composition, the preparation raw materials of which include spinosad, flubrocythrinate, wetting dispersant, dispersant, etc. The wetting dispersant includes sodium methyl naphthalene sulfonate formaldehyde condensate, and the dispersant includes sodium lignosulfonate. The synergistic pesticide composition has good control effect on pests of Lepidoptera, Thysanoptera, Diptera, Coleoptera and Homoptera. Similarly, Chinese Patent Application CN119032949A discloses a spinosad·flubrocythrinate suspension agent, the preparation raw materials of which include spinosad, flubrocythrinate and wetting agent. The wetting agent is fatty alcohol polyoxyethylene ether. The product can be well applied to preventing plant pests.

[0003] However, for pesticide suspension agent products, in addition to the consideration of efficacy, the physical stability of the product also needs to be focused on. Spinosad is easy to crystallize in water, and the hydrophobicity of flubrocythrinate may cause particle aggregation or sedimentation. If the dispersant or wetting agent is not properly selected, such as sodium lignosulfonate and fatty alcohol polyoxyethylene ether, the phenomenon of delamination, precipitation or particle size increase may occur, affecting the uniformity of efficacy.

[0004] Therefore, it is urgent to develop a spinosad·flubrocythrinate suspension agent with high stability to improve the control effect on pests such as Frankliniella occidentalis, reduce the frequency of use and application, reduce the risk of resistance, and at the same time reduce the impact on the environment and harm to non-target organisms. SUMMARY

[0005] In order to solve the above technical problems, the present application provides a 10% spinosad·flubrocythrinate suspension agent, the preparation raw materials of which include 5-20 parts of pesticide raw material, 1-10 parts of dispersant, 1-10 parts of antifreeze, 1-20 parts of thickening agent, 0.1-1 part of preservative, 0.1-1 part of defoaming agent and 50-100 parts of deionized water.

[0006] As an implementable case, the pesticide raw material includes spinosad raw material and flubrocythrinate raw material, and the mass concentration of the spinosad raw material and the flubrocythrinate raw material is 90-98 wt%.

[0007] Furthermore, the mass ratio of spinosad technical to acetamiprid technical is (1-5):(5-10).

[0008] Furthermore, the mass concentration of spinosad technical is 93 wt%, the mass concentration of azoxystrobin technical is 97 wt%, and the mass ratio of spinosad technical to azoxystrobin technical is 2.67:7.73, that is, the mass ratio of the effective mass of spinosad technical to the effective mass of azoxystrobin technical is 1:3 (2.5:7.5).

[0009] Thrips are small pests with piercing-sucking mouthparts, and it is common to see adults, nymphs, and eggs coexisting in the field. Spinosad can quickly knock down adult thrips, while acetamiprid effectively inhibits the hatching of thrips eggs and the growth and development of nymphs. A 1:3 mass ratio of the two can comprehensively cover different growth stages of thrips, achieving precise and efficient control. Furthermore, spinosad primarily acts on the nicotinic acetylcholine receptors of thrips and other pests, causing nerve excitation, paralysis, and death, with a rapid onset of action. Acetamiprid, on the other hand, inhibits the oxidative phosphorylation process in pests, blocking their energy metabolism, and also has an inhibitory effect on eggs and nymphs, with a long-lasting effect. Combining the two allows the rapid action of spinosad and the long-lasting effect of acetamiprid to organically combine, exerting a synergistic effect, rapidly reducing pest numbers while effectively inhibiting their re-infestation and extending the duration of effectiveness. Secondly, spinosad belongs to IRAC Group 5 insecticides, while acetamiprid belongs to IRAC Group 21 insecticides. The two have different targets, which can reduce the risk of pests developing resistance to a single agent and extend the lifespan of the agent.

[0010] However, spinosad is prone to crystallization in water, while acetamiprid has a certain degree of hydrophobicity. This application achieves a better balance in the physical stability of the suspension formulation by compounding spinosad and acetamiprid in a 1:3 ratio and adding appropriate dispersants and other adjuvants. On the one hand, the hydrophobicity of acetamiprid can reduce the tendency of spinosad to crystallize in water to a certain extent; on the other hand, the presence of spinosad also helps improve the dispersibility of acetamiprid in the formulation, preventing particle aggregation or sedimentation, thereby improving the stability of the suspension. This allows for a suitable reduction in the dosage of spinosad while ensuring control efficacy, minimizing the impact on beneficial organisms such as bees, and improving the product's environmental friendliness and crop safety.

[0011] As an example of an implementable method, the dispersant includes polycarboxylate wetting and dispersing agents, naphthalene sulfonate wetting and dispersing agents, and block polyether emulsifying and dispersing agents.

[0012] Further, the mass ratio of the polycarboxylate wetting dispersant, the naphthalenesulfonate wetting dispersant, and the block polyether emulsifying dispersant is (3-5) : (1-3) : (1-2).

[0013] Further, the mass ratio of the polycarboxylate wetting dispersant, the naphthalenesulfonate wetting dispersant, and the block polyether emulsifying dispersant is 4:1.5:1; wherein the polycarboxylate wetting dispersant has a brand of PRTech-D8207, the naphthalenesulfonate wetting dispersant has a brand of PRTech-D8605, and the block polyether emulsifying dispersant has a brand of PRTech-D8969, and the three components are all purchased from Shanghai PRTech Industrial Technology Co., Ltd.

[0014] The dispersibility of spinosad and pyridalyl in the aqueous phase is poor and easy to agglomerate. The polycarboxylate wetting dispersant and the naphthalenesulfonate wetting dispersant can be adsorbed on the surface of the solid particles to generate electrostatic repulsion, so that the particles are uniformly dispersed and agglomeration is prevented. The block polyether emulsifying dispersant further enhances the dispersing effect through steric hindrance and the like, and avoids the particles from gathering due to the increase in thermal motion at high temperatures. In a high-temperature environment, the compounded dispersant can stabilize the system of the suspension concentrate. The strong electrolyte stability of the polycarboxylate dispersant ensures that it can still play a role at high temperatures, preventing the particles from settling; the naphthalenesulfonate dispersant is resistant to high temperatures and can maintain the stability of the dispersion system; and the emulsifying effect of the block polyether emulsifying dispersant can prevent the oil phase from separating from the water phase, and the three components compounded together can ensure the uniformity of the suspension concentrate.

[0015] In addition, low temperature can increase the viscosity of the suspension concentrate, leading to particle settling and aggregation. The polycarboxylate and naphthalenesulfonate dispersants can still be adsorbed on the surface of the particles at low temperatures, maintaining electrostatic repulsion and preventing the particles from settling due to the increase in viscosity at low temperatures. The steric hindrance effect of the block polyether emulsifying dispersant can further prevent particle aggregation. Under low-temperature conditions, phase separation or delamination may occur in the system, but the emulsifying performance of the block polyether emulsifying dispersant can keep the oil phase and the water phase uniformly mixed at low temperatures, preventing phase separation, and the polycarboxylate and naphthalenesulfonate dispersants ensure that the solid particles can still be uniformly dispersed in the aqueous phase at low temperatures. After the three components are compounded, the adsorption effect of the dispersant can interfere with the crystallization process of spinosad, making it difficult for spinosad to form a regular crystal structure at low temperatures, thereby reducing crystallization and improving the low-temperature stability of the suspension concentrate.

[0016] As an implementable case, the antifreeze agent includes one or more of methanol, ethanol, isopropyl alcohol, ethylene glycol, propylene glycol, diethylene glycol, ethylene glycol butyl ether, propylene glycol butyl ether, ethylene glycol butyl ether acetate, dichloromethane, 1,1-dichloroethane, 1,2-dichloroethane, dimethyl sulfoxide, formamide, calcium chloride, sodium acetate, and magnesium chloride.

[0017] Further, the antifreeze agent is ethylene glycol.

[0018] Ethylene glycol can significantly reduce the freezing point of water, so that the suspension agent remains liquid at low temperature environment to prevent water from freezing. Spinosad is prone to crystallization in water, and the addition of ethylene glycol can reduce the risk of crystallization. At the same time, ethylene glycol and dispersants, thickeners and other additives synergistically enhance the wetting and dispersing effect of the dispersant, thereby improving the thermal storage and low temperature stability of the suspension agent.

[0019] As an implementable case, the thickening agent includes one or more of xanthan gum, sodium carboxymethyl cellulose, sodium polyacrylate, polyvinylpyrrolidone, and magnesium aluminum silicate.

[0020] Further, the thickening agent is xanthan gum and magnesium aluminum silicate, and the mass ratio of xanthan gum to magnesium aluminum silicate is (0.1-0.2):(1-2). In the present application, xanthan gum is used in the form of an aqueous solution.

[0021] Xanthan gum has strong thickening ability and can form a network structure in water, significantly increasing the viscosity of the system and reducing the flowability of the suspension agent, which helps to slow down the settling speed of spinosad and flubendiamide particles, so that the particles are more stably dispersed in the aqueous phase. Magnesium aluminum silicate is an inorganic gel thickening agent that has a layered structure and can form a gel network structure in the aqueous phase to adsorb water molecules and solid particles, further increasing the viscosity of the system and enhancing the thickening effect of the suspension agent. When the two are compounded, the thickening effect is complementary, making the viscosity of the suspension agent more uniform and stable, preventing the particles from settling, delaminating, and other unstable phenomena during storage and transportation.

[0022] In the present application, the components of the preservative are not further limited, and any chemical additive that can effectively improve the preservative performance of the suspension agent can be used, including but not limited to preservative KM10.

[0023] Similarly, the components of the defoaming agent are not further limited in the present application, and any chemical additive that can effectively reduce the production of foam during preparation can be used, including but not limited to defoaming agent X-513.

[0024] The second aspect of the present application provides a preparation method of 10% spinosad·flubendiamide suspension agent, comprising:

[0025] Mixing the pesticide raw material, dispersant, antifreeze, thickening agent, preservative, defoaming agent and deionized water uniformly, shearing into a uniform slurry, pouring the slurry into a sand mill with sand grinding beads, and continuously sand grinding for 1-1.5 hours, then adding the thickening agent and continuing to sand grind, to obtain 10% spinosad·flubendiamide suspension agent.

[0026] Further, the preparation method of 10% spinosad·flubendiamide suspension agent comprises:

[0027] In a beaker, first add deionized water, antifreeze agent, polycarboxylate wetting dispersant, naphthalene sulfonate wetting dispersant, polyether emulsifying dispersant, magnesium aluminum silicate, stir until uniform, then add spinosad technical material and clothianidin technical material, drop in defoaming agent and preservative, shear into uniform slurry, pour the slurry into a sand mill with sanding beads, continuously sand mill for 1 hour, then add xanthan gum, continue sanding for 10 minutes, to obtain 10% spinosad·clothianidin suspension concentrate.

[0028] Advantages

[0029] (I) In the present application, spinosad and clothianidin are selected as the technical material for compounding, spinosad mainly acts on the nicotinic acetylcholine receptor, while the main mechanism of action of clothianidin is to inhibit oxidative phosphorylation, the two components have complementary action mechanisms, can quickly knock down adult insects, and have long-term inhibition on eggs and nymphs, covering the entire life period of thrips.

[0030] (II) In the present application, the dispersant combination is optimized, three components of polycarboxylate wetting dispersant, naphthalene sulfonate wetting dispersant and block polyether emulsifying dispersant are selected for compounding, to ensure the stability of the suspension concentrate in hot storage and cold storage, without caking or stratification.

[0031] (III) In addition to thrips, clothianidin also has activity against aphids, whiteflies, leafminers, etc., and spinosad can also treat lepidopteran larvae, therefore the suspension concentrate provided by the present application can be used on eggplants to control thrips, reduce the number of applications, and has broad-spectrum insecticidal effect.

[0032] (IV) Spinosad is a biological insecticide, which can be used for green food production; clothianidin has low toxicity to mammals, and meets the environmental protection requirements. By optimizing the dosage form and adjuvants, the irritability to eggplants can be reduced, the risk of phytotoxicity is reduced, and the impact on beneficial organisms such as bees is also relatively small.

[0033] (V) In the present application, spinosad belongs to the 5th group of insecticides according to IRAC, and clothianidin belongs to the 21st group of insecticides according to IRAC, the two have different target points, when used in a mass ratio of 1:3, the risk of resistance of pests to a single pesticide can be reduced, and the service life of the pesticide can be prolonged. BRIEF DESCRIPTION OF DRAWINGS

[0034] Figure 1 Picture of the appearance of the 10% spinosad·clothianidin suspension concentrate prepared in Example 1.

[0035] Figure 2 Picture of the appearance of the 10% spinosad·clothianidin suspension concentrate prepared in Example 4. DETAILED DESCRIPTION

[0036] In the following Examples 1-8, the relevant raw material information is shown in Table 1.

[0037] Table 1

[0038]

[0039] Example 1

[0040] The first aspect of the example provides a 10% spinosad·flubrocyliate suspension agent, which is prepared from raw materials according to the mass, specifically 10.42 g of pesticide raw material, 6.5 g of dispersant, 4 g of antifreeze, 13.2 g of thickening agent, 0.3 g of preservative, 0.3 g of defoaming agent, and 65.28 g of deionized water.

[0041] The pesticide raw material specifically includes 2.69 g of spinosad raw material with a mass concentration of 93 wt% (the effective content of spinosad is 2.5 g) and 7.73 g of flubrocyliate raw material with a mass concentration of 97 wt% (the effective content of flubrocyliate is 7.5 g).

[0042] The dispersant is a polycarboxylate wetting dispersant, a naphthalene sulfonate wetting dispersant, and a block polyether emulsification dispersant; the mass ratio of the polycarboxylate wetting dispersant, the naphthalene sulfonate wetting dispersant, and the block polyether emulsification dispersant is 4:1.5:1.

[0043] The antifreeze is ethylene glycol.

[0044] The thickening agent specifically includes 1.2 g of magnesium aluminum silicate and 12 g of 1.5 wt% xanthan gum aqueous solution (the effective mass content of xanthan gum is 0.18 g).

[0045] The preservative is preservative KM10.

[0046] The defoaming agent is defoaming agent X-513.

[0047] The second aspect of the example provides a preparation method of a 10% spinosad·flubrocyliate suspension agent, which specifically includes the following steps.

[0048] First, deionized water, ethylene glycol, a polycarboxylate wetting dispersant, a naphthalene sulfonate wetting dispersant, a block polyether emulsification dispersant, and magnesium aluminum silicate are added into a 150 mL beaker and stirred uniformly, then spinosad raw material and flubrocyliate raw material are added, defoaming agent X-513 and preservative KM10 are added dropwise, and a uniform slurry is obtained through shearing, the slurry is poured into a 0.1 L vertical small sand mill with sand beads in a laboratory, and continuous sand milling is performed for 1 hour, then xanthan gum aqueous solution is added, and sand milling is continuously performed for 10 minutes, thereby obtaining a 10% spinosad·flubrocyliate suspension agent.

[0049] The appearance of the 10% spinosad·flubrocyliate suspension agent prepared in the example is shown in FIG. 1. Figure 1

[0050] Example 2​

[0051] The specific embodiment of this example is the same as that of Example 1, except that:

[0052] 1. The preparation raw materials of the 10% spinosad·tolfenpyrad suspension agent are 10.42 g of pesticide raw drug, 6 g of dispersant, 4 g of antifreeze, 13.2 g of thickening agent, 0.3 g of preservative, 0.3 g of defoaming agent, and 65.78 g of deionized water.

[0053] 2. The dispersant is a naphthalene sulfonate wetting dispersant.

[0054] Example 3

[0055] The specific embodiment of this example is the same as that of Example 1, except that:

[0056] 1. The preparation raw materials of the 10% spinosad·tolfenpyrad suspension agent are 10.42 g of pesticide raw drug, 5.5 g of dispersant, 4 g of antifreeze, 13.2 g of thickening agent, 0.3 g of preservative, 0.3 g of defoaming agent, and 66.28 g of deionized water.

[0057] 2. The dispersant is a polycarboxylate wetting dispersant.

[0058] Example 4

[0059] The specific embodiment of this example is the same as that of Example 1, except that:

[0060] 1. The preparation raw materials of the 10% spinosad·tolfenpyrad suspension agent are 10.42 g of pesticide raw drug, 5.5 g of dispersant, 4 g of antifreeze, 13.2 g of thickening agent, 0.3 g of preservative, 0.3 g of defoaming agent, and 66.28 g of deionized water.

[0061] 2. The dispersant is a carboxylate wetting dispersant.

[0062] The appearance picture of the 10% spinosad·tolfenpyrad suspension agent prepared in this example is shown in Figure 2 .

[0063] Example 5

[0064] The specific embodiment of this example is the same as that of Example 1, except that:

[0065] 1. The preparation raw materials of the 10% spinosad·tolfenpyrad suspension agent are 10.42 g of pesticide raw drug, 7.0 g of dispersant, 4 g of antifreeze, 13.2 g of thickening agent, 0.3 g of preservative, 0.3 g of defoaming agent, and 64.78 g of deionized water.

[0066] 2. The dispersant is a sulfonate wetting dispersant.

[0067] Example 6

[0068] The specific implementation of this example is the same as that of Example 1, except that:

[0069] 1. The preparation raw materials of the 10% spinosad·zoxamid suspension agent are 10.42 g of pesticide raw material, 6.5 g of dispersant, 4 g of antifreeze, 13.2 g of thickening agent, 0.3 g of preservative, 0.3 g of defoaming agent, and 65.28 g of deionized water.

[0070] 2. The dispersant is modified castor oil polyoxyethylene ether.

[0071] Example 7

[0072] The specific implementation of this example is the same as that of Example 1, except that:

[0073] 1. The preparation raw materials of the 10% spinosad·zoxamid suspension agent are 10.42 g of pesticide raw material, 7.0 g of dispersant, 4 g of antifreeze, 13.2 g of thickening agent, 0.3 g of preservative, 0.3 g of defoaming agent, and 64.78 g of deionized water.

[0074] 2. The dispersant is sodium lignosulfonate.

[0075] Example 8

[0076] The specific implementation of this example is the same as that of Example 1, except that:

[0077] 1. The preparation raw materials of the 10% spinosad·zoxamid suspension agent are 10.42 g of pesticide raw material, 5.5 g of dispersant, 4 g of antifreeze, 13.2 g of thickening agent, 0.3 g of preservative, 0.3 g of defoaming agent, and 66.28 g of deionized water.

[0078] 2. The dispersant is a non-ionic block polyether wetting dispersant.

[0079] Performance test

[0080] I. Physicochemical performance test

[0081] The 10% spinosad·zoxamid suspension agent should be a milky white, flowable, and easy to measure volume suspension; during storage, sedimentation may occur, but after shaking, it returns to its original state, and there should be no lumps, and the technical indicators meet the requirements of Table 2.

[0082] Table 2

[0083]

[0084]

[0085] II. Pesticide stability and physicochemical property test

[0086] Test object: 10% spinosad · flubrocydamate suspension concentrate prepared in Examples 1-8.

[0087] The test items and experimental results are shown in Table 3.

[0088] Table 3

[0089]

[0090]

[0091]

[0092] Among them, the relevant test standards are as follows:

[0093] GB / T 1601: Determination of pH value of pesticides;

[0094] GB / T 1604: Acceptance rules for commercial pesticides;

[0095] GB / T 1605-2001: Sampling method for commercial pesticides;

[0096] GB 3796: General rules for pesticide packaging;

[0097] GB / T 8170-2008: Numerical rounding rules and representation and determination of limit values;

[0098] GB / T 14825-2006: Determination method of pesticide suspension rate;

[0099] GB / T 16150-1995: Determination method of fineness of pesticide powder and wettable powder;

[0100] GB / T 19136-2021: Determination method of thermal storage stability of pesticides;

[0101] GB / T 19137-2003: Determination method of low temperature stability of pesticides;

[0102] GB / T 28137: Determination method of persistent foaming property of pesticides;

[0103] GB / T 31737: Determination method of pourability of pesticides;

[0104] GB / T 32776-2016: Determination method of pesticide density requirements.

[0105] From the experimental results of Table 3, it can be seen that by selecting the polycarboxylate wet dispersant, naphthalene sulfonate wet dispersant and block polyether emulsifying dispersant in Example 1 as the dispersant, the thermal storage stability and low temperature stability of 10% polyoxin · azadirachtin suspension concentrate can be effectively improved; the dispersants disclosed in Examples 2-8 are not conducive to improving the stability of the suspension concentrate.

[0106] Four, field experiment

[0107] The test was carried out in Hongwei Village, Tahe Town, Dongpo District, Meishan City, Sichuan Province in July 2021, and the occurrence of tomato thrips was serious in the test field for many years. The agricultural control effect of different suspensions was tested, 4 times were repeated, and the area of each plot was 20m 2 , a total of 28 plots, arranged in random blocks. Spray method was used, and the tomato was in flowering and fruiting period and the thrips occurred at the beginning of the treatment. The pesticide solution was prepared by twice dilution method, and sprayed uniformly by sprayer. Another water treatment was used as blank control. The water consumption of each plot was about 1.8 liters, and the water consumption per hectare was about 900 liters. The insect population base was investigated before treatment, and the investigation was carried out once at 1, 3, 7 and 10 days after treatment, and the control effect of the pesticide was evaluated. The test results are shown in Table 4.

[0108]

[0109] Among them, the method for calculating the efficacy is:

[0110] Control effect (%) = (CK1xPT0-CK0xPT1) / (CK1xPT0)x100%;

[0111] Or control effect (%) = (PT-CK) / (100-CK)x100%.

[0112] Among them, PT0---the number of insects in the treatment area before treatment;

[0113] PT---the number of insects in the treatment area after treatment;

[0114] CK0---the number of insects in the blank control area before treatment;

[0115] CK1---the number of insects in the blank control area after treatment;

[0116] PT---insect population reduction rate in the treatment area;

[0117] CK---insect population reduction rate in the blank control area.

[0118] From the experimental results of Table 4, it can be seen that the use of 10% polyoxin · azadirachtin suspension concentrate has more excellent agricultural control effect compared with the suspension concentrate of single component raw material.

Claims

1. A 10% spinosad·safroxan suspension agent, characterized by, The raw materials are prepared according to the mass fraction, including 5-20 parts of pesticide raw drug, 1-10 parts of dispersant, 1-10 parts of antifreeze, 1-20 parts of thickening agent, 0.1-1 parts of preservative, 0.1-1 parts of defoaming agent, 50-100 parts of deionized water; The pesticide raw material includes spinosad raw drug and clothianidin raw drug, and the mass concentration of the spinosad raw drug and the clothianidin raw drug is 90-98wt%.

2. The 10% spinosad·sulfoxaflor suspension according to claim 1, characterized in that, The mass ratio of the spinosad raw drug and the clothianidin raw drug is (1-5):(5-10).

3. The 10% spinosad·safroxan suspension agent according to claim 1, characterized by, The dispersant includes polycarboxylate wet dispersant, naphthalene sulfonate wet dispersant and block polyether emulsification dispersant.

4. The 10% spinosad·safroxan suspension agent according to claim 3, characterized by, The mass ratio of the polycarboxylate wet dispersant, the naphthalene sulfonate wet dispersant and the block polyether emulsification dispersant is (3-5):(1-3):(1-2).

5. The 10% spinosad·safroxan suspension agent according to claim 1, characterized by, The antifreeze includes one or more of methanol, ethanol, isopropyl alcohol, ethylene glycol, propylene glycol, diethylene glycol, ethylene glycol butyl ether, propylene glycol butyl ether, ethylene glycol butyl ether acetate, dichloromethane, 1,1-dichloroethane, 1,2-dichloroethane, dimethyl sulfoxide, formamide, calcium chloride, sodium acetate, magnesium chloride.

6. The 10% spinosad·safroxan suspension agent according to claim 1, characterized by, The thickening agent includes one or more of xanthan gum, carboxymethyl cellulose sodium, polyacrylic acid sodium, polyvinylpyrrolidone, magnesium aluminum silicate.

7. The 10% spinosad·safroxan suspension agent according to claim 6, characterized by, The mass ratio of the xanthan gum and the magnesium aluminum silicate is (0.1-0.2):(1-2).

8. The 10% spinosad·safroxan suspension according to any one of claims 1 to 7, characterized in that The preservative includes preservative KM10.

9. The 10% spinosad·safroxan suspension agent according to claim 1, characterized by, The defoaming agent includes defoaming agent X-513.

10. A process for the preparation of a 10% spinosad·safylfluarid suspension according to any one of claims 1-9, characterized in that, Including: Mixing the pesticide raw drug, the dispersant, the antifreeze, the thickening agent, the preservative, the defoaming agent and the deionized water uniformly, shearing into uniform slurry, pouring the slurry into a sand mill with sand grinding beads, continuously sand grinding for 1-1.5 hours, then adding the thickening agent and continuing to sand grind, to obtain 10% spinosad·clothianidin suspension concentrate.

Images