Composition capable of tightening skin as well as preparation process and application of composition

Abstract

The invention relates to the technical field of raw materials of skin care products, and particularly discloses a composition capable of tightening and tightening skin and a preparation technology and application thereof.The composition capable of tightening and tightening skin is prepared from, by mass, 84.17-86.42 parts of solvent; 0.8-1 part of a preservative; 9 to 10.31 parts of a skin conditioner; 3.78 to 4.52 parts of a composite extract; the compound extract is prepared by compounding a pueraria mirifica extract, a reed extract, a gymnema sylvestre leaf extract and an exhaustive dracocephalum herb extract. The invention has the advantage of further improving the effect of tightening and tightening the skin.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of skin care raw materials, in particular to a composition for tightening skin and a preparation process and application thereof. BACKGROUND

[0002] With the aggravation of the social aging trend, people's demand for delaying skin aging, maintaining skin elasticity and tightening is growing.

[0003] The existing skin care products add raw materials for removing free radicals, so that the skin care products have the effect of removing free radicals, at the same time reducing the attack of free radicals on the skin, playing the effect of antioxidant, thereby delaying skin aging.

[0004] However, the existing skin care products have poor effect of removing free radicals, and lack the effect of relieving skin aging and restoring skin elasticity in multiple aspects, resulting in that the effect of tightening skin is difficult to achieve the expected effect, so there is still room for improvement. SUMMARY

[0005] In order to further improve the effect of tightening skin, the present application provides a composition for tightening skin and a preparation process and application thereof.

[0006] In the first aspect, the present application provides a composition for tightening skin, which adopts the following technical scheme: A composition for tightening skin, comprising the following components in mass fraction: 84.17-86.42 parts of solvent; 0.8-1 part of preservative; 9-10.31 parts of skin conditioning agent; 3.78-4.52 parts of composite extract; The composite extract is a compound of wild kudzu root extract, reed grass extract, Gymnema leaf extract and radix kirkii extract.

[0007] By adopting the technical scheme, the addition of the kudzu vine root extract is conducive to removing excessive free radicals in the skin, reducing the damage of oxidative stress to fibroblasts and collagen, enhancing the tightness and elasticity of the skin, and making the skin tightening effect of the composite extract better. The addition of the reed grass extract is conducive to inhibiting the production of skin glycosylation end products (AGEs), protecting existing collagen fibers from glycosylation damage, and making the skin tightening effect of the composite extract better. The addition of the gymnema leaf extract is conducive to inhibiting the production of 5-alpha reductase, reducing oil secretion, making the skin more delicate, smooth and firm, and making the skin tightening effect of the composite extract better. The addition of the gymnadenia extract is conducive to inhibiting the activity of elastase in the skin, protecting elastic fibers, and increasing skin elasticity, and making the skin tightening effect of the composite extract better.

[0008] Therefore, by adding the composite extract compounded by the kudzu vine root extract, the reed grass extract, the gymnema leaf extract and the gymnadenia extract, under the mutual cooperation of the active ingredients, a very significant free radical scavenging effect can be achieved, the attack of free radicals on the skin can be significantly reduced, a good anti-glycosylation effect can be achieved, tissue damage and aging caused by glycosylation reaction can be reduced, and the activity of elastase can be significantly inhibited, which helps to promote the recovery of elastin, so that the skin can be significantly restored to youth, and under the action of the reconstruction of elastin, the skin can be quickly restored to be tight and elastic, and a significant skin tightening effect can be achieved.

[0009] Preferably, in the composite extract, the mass ratio of the kudzu vine root extract, the reed grass extract, the gymnema leaf extract and the gymnadenia extract is 0.9-1.1:1.8-2.2:0.08-0.12:1-1.1.

[0010] By adopting the technical scheme, by specifically selecting the mass ratio of the kudzu vine root extract, the reed grass extract, the gymnema leaf extract and the gymnadenia extract, the active ingredients can be better matched in a specific ratio, the mutual cooperation effect is more significant, better antioxidant, anti-glycosylation and elastase inhibition effects can be achieved, and the skin tightening effect is more significant.

[0011] Preferably, the skin conditioner is a compound of crocus extract, soybean isopropyl ketone, rhamnus fruit extract, L-carnitine, licorice extract, dendrobium nobile extract, mulberry leaf extract, radix astragali extract, radix rehmanniae extract and radix anemarrhenae extract.

[0012] By adopting the above technical solution, and specifically selecting a combination of skin conditioning agents such as saffron extract, soy isopropyl ketone, kudzu root extract, L-carnitine, licorice extract, dendrobium nobile extract, mulberry leaf extract, astragalus extract, rehmannia root extract, and anemarrhena root extract, a good skin conditioning effect can be achieved, making the skin healthier and better improving the skin firming and tightening effect.

[0013] Preferably, in the skin conditioning agent, the mass ratio of saffron extract, soy isopropyl ketone, sausage fruit extract, L-carnitine, licorice extract, dendrobium nobile extract, mulberry leaf extract, astragalus extract, rehmannia root extract, and anemarrhena root extract is 0.2-0.4:0.9-1.1:0.9-1.1:0.1-0.11:1.9-2.1:1-1.1:1-1.1:1-1.1:1-1.1:1-1.1:1-1.1.1.

[0014] By adopting the above technical solution and specifically selecting the mass ratio of saffron extract, soy isopropyl ketone, kudzu root extract, L-carnitine, licorice extract, dendrobium nobile extract, mulberry leaf extract, astragalus extract, rehmannia root extract, and anemarrhena root extract, the skin care effect is made more significant.

[0015] Preferably, the preservative is a combination of p-hydroxyacetophenone and 1,2-hexanediol.

[0016] By adopting the above technical solution and specifically selecting p-hydroxyacetophenone and 1,2-hexanediol, the preservative effect is better, the product quality is more stable, and the irritation is lower, making it more skin-friendly.

[0017] Preferably, the mass ratio of p-hydroxyacetophenone to 1,2-hexanediol in the preservative is 0.4-0.5:0.4-0.5.

[0018] By adopting the above technical solution and specifically selecting the mass ratio of p-hydroxyacetophenone and 1,2-hexanediol, a better anti-corrosion effect can be achieved, resulting in better product quality.

[0019] Preferably, the solvent is a mixture of water and butanediol.

[0020] By adopting the above technical solution and specifically selecting water and butanediol as the solvent, each component can be easily dissolved in the solvent, thereby enabling the various active ingredients to exert their synergistic effects.

[0021] Preferably, the mass ratio of water to butanediol in the solvent is 78.17-80.62:5.8-6.

[0022] By adopting the above technical solution and specifically selecting the mass ratio of water and butanediol, the solubility of each component can be improved even more effectively.

[0023] Secondly, this application provides a preparation process for a composition that tightens and firms the skin, using the following technical solution: A process for preparing the above-mentioned composition with skin-tightening and firming effects includes the following steps: Step 1), mix the solvent and preservative, heat to 50-55℃, stir evenly to obtain the premix; Step 2), cool the premix to 40°C or below, then add the skin conditioning agent and compound extract, mix well to obtain a composition that tightens and firms the skin.

[0024] By adopting the above technical solution, the resulting composition with skin-tightening properties can impart significant antioxidant, anti-glycation, and elastase-inhibiting effects to skincare products, resulting in products with significant skin-tightening effects.

[0025] Thirdly, this application provides an application of a composition that tightens and firms the skin, employing the following technical solution: An application of the above-mentioned composition having skin-tightening effect, wherein the composition having skin-tightening effect is added to the formulation of a skin care product or cosmetic product for the preparation of a skin care product or cosmetic product having skin-tightening effect.

[0026] By adopting the above technical solutions, the resulting skin care or cosmetic products can quickly tighten the skin, allowing it to quickly regain its elasticity, and have a very significant skin-tightening effect.

[0027] In summary, this application has the following beneficial effects: 1. Because this application uses a compound extract composed of Pueraria lobata extract, Reed sibiricum extract, Gymnema sylvestre leaf extract, and Dracaena cochinchinensis extract, the synergistic effect of each active ingredient can significantly reduce the attack of free radicals on the skin. It can also have a good anti-glycation effect, reducing tissue damage and aging caused by glycation reaction. Furthermore, it can significantly inhibit the activity of elastase, which helps to promote the recovery of elastin, thereby enabling the skin to significantly regain its youthful appearance. At the same time, under the action of elastin reconstruction, it can quickly restore firmness and elasticity, thus achieving a significant skin tightening and firming effect.

[0028] 2. In this application, the preferred method is to select the specific mass ratio of Pueraria lobata extract, Reed sibiricum extract, Gymnema sylvestre leaf extract, and Dracaena cochinchinensis extract so that the active ingredients can be better combined in a specific ratio, and the synergistic effect is more significant. This results in better antioxidant, anti-glycation, and elastase inhibition effects, and a more significant skin-tightening effect.

[0029] 3. In this application, the preferred skin conditioning agents are a combination of saffron extract, soy isopropyl ketone, sausage fruit extract, L-carnitine, licorice extract, dendrobium nobile extract, mulberry leaf extract, astragalus extract, rehmannia root extract, and anemarrhena root extract, which can achieve a better skin conditioning effect, making the skin healthier and improving the skin tightening effect. Detailed Implementation

[0030] The present application will be further described in detail below with reference to the embodiments. Example

[0031] A composition for firming and tightening the skin, and a method for preparing the composition for firming and tightening the skin is as follows: Step 1): Add water, butanediol, p-hydroxyacetophenone, and 1,2-hexanediol to a mixing tank, heat to 50°C, rotate at 40 r / min, and stir for 15 min until homogeneous to obtain a premix.

[0032] Step 2): Cool the premix to 35°C, then add saffron extract, soy isoacetone, sausage fruit extract, L-carnitine, licorice extract, dendrobium nobile extract, mulberry leaf extract, astragalus extract, rehmannia root extract, anemarrhena root extract, kudzu root extract, reed extract, gymnasium leaf extract, and dragon's blood extract. Stir at 40 rpm for 15 minutes until well mixed to obtain a composition that tightens and firms the skin.

[0033] The specific input amounts of each raw material in the preparation method are detailed in Table 1.

[0034] For details on the source information of each raw material in the preparation method, please refer to Table 2. Example

[0035] A composition for firming and tightening the skin, and a method for preparing the composition for firming and tightening the skin is as follows: Step 1): Add water, butanediol, p-hydroxyacetophenone, and 1,2-hexanediol to a mixing tank, heat to 52.5°C, rotate at 50 r / min, and stir for 17.5 min until homogeneous to obtain a premix.

[0036] Step 2): Cool the premix to 37.5°C, then add saffron extract, soy isoacetone, sausage fruit extract, L-carnitine, licorice extract, dendrobium nobile extract, mulberry leaf extract, astragalus extract, rehmannia root extract, anemarrhena root extract, kudzu root extract, reed extract, gymnasium leaf extract, and dragon's blood extract. Stir at 50 rpm for 17.5 minutes until well mixed to obtain a composition that tightens and firms the skin.

[0037] The specific input amounts of each raw material in the preparation method are detailed in Table 1.

[0038] For details on the source information of each raw material in the preparation method, please refer to Table 2. Example

[0039] A composition for firming and tightening the skin, and a method for preparing the composition for firming and tightening the skin is as follows: Step 1): Add water, butanediol, p-hydroxyacetophenone, and 1,2-hexanediol to a mixing tank, heat to 55°C, rotate at 60 r / min, and stir for 20 min until homogeneous to obtain a premix.

[0040] Step 2): Cool the premix to 40°C, then add saffron extract, soy isopropyl ketone, sausage fruit extract, L-carnitine, licorice extract, dendrobium nobile extract, mulberry leaf extract, astragalus extract, rehmannia root extract, anemarrhena root extract, kudzu root extract, reed extract, gymnasium leaf extract, and dragon's blood extract. Stir at 60 rpm for 20 minutes until well mixed to obtain a composition that tightens and firms the skin.

[0041] The specific input amounts of each raw material in the preparation method are detailed in Table 1.

[0042] For details on the source information of each raw material in the preparation method, please refer to Table 2.

[0043] Comparative Example 1 A composition that tightens and firms the skin, differing from Example 2 only in that: Centella asiatica extract was used to replace Pueraria lobata extract in an equal amount.

[0044] For details on the source of raw materials, please refer to Table 2.

[0045] Comparative Example 2 A composition that tightens and firms the skin, differing from Example 2 only in that: Hops extract was used to replace reed extract in an equal amount.

[0046] For details on the source of raw materials, please refer to Table 2.

[0047] Comparative Example 3 A composition that tightens and firms the skin, differing from Example 2 only in that: The extract of Gymnema sylvestris leaf was replaced with an equal amount of bitter melon fruit extract.

[0048] For details on the source of raw materials, please refer to Table 2.

[0049] Comparative Example 4 A composition that tightens and firms the skin, differing from Example 2 only in that: Myrrh extract was used to replace the blood draconis extract in an equal amount.

[0050] For details on the source of raw materials, please refer to Table 2.

[0051] Comparative Example 5 A composition that tightens and firms the skin, differing from Example 2 only in that: Centella asiatica extract was used to replace Pueraria lobata extract in equal amounts; hops extract was used to replace Reed sedge extract in equal amounts; bitter melon fruit extract was used to replace Gymnema sylvestre leaf extract in equal amounts; and myrrh extract was used to replace Dracaena cochinchinensis extract in equal amounts.

[0052] Table 1. Amount of each raw material used in the preparation methods of each embodiment (unit: kg)

[0053] Table 2. Source information of each raw material in each embodiment and comparative example

[0054]

[0055]

[0056] Experiment 1 The DPPH free radical scavenging rate (%) of the skin-tightening compositions in each example and comparative example was tested according to T / SHRH 006—2018 "Cosmetics - Test Method for Free Radical (DPPH) Scavenging".

[0057] The experimental data are detailed in Table 3.

[0058] Experiment 2 According to T / AHPCA 047-2023 "Test Method for Anti-wrinkle and Firming Efficacy of Cosmetics (Rapid Determination of Elastase Inhibition)", the elastase inhibition rate (%) of the compositions with skin-tightening and firming effects in each example and comparative example was tested.

[0059] The experimental data are detailed in Table 3.

[0060] Experiment 3 In vitro anti-glycation experiment 1. Experimental Objective The in vitro anti-glycation properties of test samples prepared from the skin-tightening compositions of each embodiment and comparative example were determined.

[0061] 2. Experimental Principle Non-enzymatic glycosylation (NEG), commonly known as glycation, refers to the non-enzymatic condensation reaction between the carbonyl group on reducing sugars (such as glucose) and the free amino group on macromolecules such as proteins, lipids, or nucleic acids. The stable covalent adducts generated by the NEG reaction are called advanced glycation end products (AGEs). The main effects of AGEs on the skin are that they lead to skin aging and dullness.

[0062] A BSA-glucose simulated reaction system was established, with a positive control (aminoguanidine sulfate) and a blank control group set up. The fluorescence intensity of the samples was measured using a multifunctional microplate reader, and the inhibition rate of fluorescent AGEs was calculated to reflect the anti-glycation effect of the test samples. 3. Experimental materials and instruments Samples: Compositions with skin-tightening and firming effects in various embodiments and comparative examples, aminoguanidine sulfate (AG).

[0063] Reagents and consumables: black bottom transparent 96-well plate, dipotassium hydrogen phosphate, potassium dihydrogen phosphate, bovine serum albumin (BSA), glucose, deionized water.

[0064] Instrumentation: Multifunctional microplate reader (Infinite M200 Pro).

[0065] 4. Experimental Methods BSA-glucose model Under aseptic conditions, 2.0 mL of 20 mg / mL bovine serum albumin solution and 2.0 mL of 0.4 M glucose solution were added to centrifuge tubes and mixed thoroughly. The following test groups were set up in the experiment, and different treatments were performed: Blank control group: Phosphate buffer was added, and no treatment was performed. Experimental group: Compositions with skin-tightening and firming effects were added to each of the examples and comparative examples. Positive control group: 2.0 ml of 0.5 mg / mL (0.05%) guanidine sulfate (AG) solution Afterwards, the samples were incubated at 37°C in the dark for 40 days. The fluorescence intensity of advanced glycosylation products (AGEs) in each test group was measured using a multifunctional microplate reader under the conditions of excitation wavelength 370 nm and emission wavelength 440 nm.

[0066] 5. Data Processing AGEs inhibition rate: IR% = [1 - (Aa-Ab) / (Ac-Ad)] * ​​100% In the formula: Aa is the average fluorescence intensity of the experimental group and the positive control group, Ab is the average fluorescence intensity of the sample background well, Ac is the average fluorescence intensity of BSA and glucose in the control group, and Aa is the average fluorescence intensity of BSA.

[0067] The experimental data are detailed in Table 3.

[0068] Table 3

[0069] According to the data comparison of each embodiment and comparative example in Table 3, the DPPH free radical scavenging rate (%), elastase inhibition rate (%), and AGEs inhibition rate (%) of each embodiment are higher than those of the comparative example. This proves that by using Pueraria lobata extract, Reed sibiricum extract, Gymnema sylvestre leaf extract, and Dracaena cochinchinensis extract in a specific ratio in each embodiment, the interaction of each active ingredient can achieve a very significant effect of scavenging free radicals, anti-glycation, and inhibiting elastase activity, thereby achieving the effect of quickly tightening and firming the skin.

[0070] While the comparative examples also showed good free radical scavenging effects, their anti-glycation and elastase inhibition effects were far inferior to those of the original examples. As a result, although the comparative examples could also play a certain anti-aging role, they were unable to achieve the effect of quickly tightening and firming the skin.

[0071] This specific embodiment is merely an explanation of this application and is not intended to limit it. After reading this specification, those skilled in the art can make modifications to this embodiment without contributing any inventive step, but such modifications are protected by patent law as long as they fall within the scope of the claims of this application.

Claims

1. A composition having skin-tightening and firming effects, characterized in that: The components include the following parts by mass: Solvent: 84.17-86.42 parts; Preservative 0.8-1 part; Skin conditioning agent 9-10.31 parts; 3.78-4.52 parts of compound extract; The compound extract is a combination of Pueraria lobata extract, Reed sibiricum extract, Gymnema sylvestre leaf extract, and Dracaena cochinchinensis extract.

2. The composition for tightening and firming the skin according to claim 1, characterized in that: In the compound extract, the mass ratio of Pueraria lobata extract, Reed sibiricum extract, Gymnema sylvestre leaf extract, and Dracaena cochinchinensis extract is 0.9-1.1:1.8-2.2:0.08-0.12:1-1.

1.

3. The composition for tightening and firming the skin according to claim 1, characterized in that: The skin conditioning agent is a compound of saffron extract, soy isopropyl ketone, sausage fruit extract, L-carnitine, licorice extract, dendrobium nobile extract, mulberry leaf extract, astragalus extract, rehmannia root extract, and anemarrhena root extract.

4. The composition for tightening and firming the skin according to claim 3, characterized in that: The skin conditioning agent contains saffron extract, soy isopropyl ketone, sausage tree fruit extract, L-carnitine, licorice extract, dendrobium nobile extract, mulberry leaf extract, astragalus extract, rehmannia root extract, and anemarrhena root extract in a mass ratio of 0.2-0.4:0.9-1.1:0.9-1.1:0.1-0.11:1.9-2.1:1-1.1:1-1.1:1-1.1:1-1.1:1-1.1:1-1.1.

1.

5. The composition for tightening and firming the skin according to claim 1, characterized in that: The preservative is a combination of p-hydroxyacetophenone and 1,2-hexanediol.

6. The composition for tightening and firming the skin according to claim 5, characterized in that: In the preservative, the mass ratio of p-hydroxyacetophenone to 1,2-hexanediol is 0.4-0.5:0.4-0.

5.

7. The composition for tightening and firming the skin according to claim 1, characterized in that: The solvent is a mixture of water and butanediol.

8. The composition for tightening and firming the skin according to claim 7, characterized in that: The solvent contains water in a mass ratio of 78.17-80.62: 5.8-6.

9. A preparation process of a composition having skin-tightening and firming effects according to any one of claims 1-8, characterized in that: Includes the following steps: Step 1), mix the solvent and preservative, heat to 50-55℃, stir evenly to obtain the premix; Step 2), cool the premix to 40°C or below, then add the skin conditioning agent and compound extract, mix well to obtain a composition that tightens and firms the skin.

10. The application of a composition having skin-tightening and firming effects according to any one of claims 1-8, characterized in that: The composition having skin-tightening and firming effects is added to the formulation of skin care or cosmetic products for the preparation of skin care or cosmetic products with skin-tightening and firming effects.

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