Whitening composition and application thereof
By combining Norwegian spruce leaf extract, Indian swert sprout extract, and heather extract, the problem of existing whitening skincare products being unable to completely inhibit tyrosinase activity has been solved, achieving significant whitening effects and improved skin health.
Patent Information
- Application Number
- CN202511478686.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-10-16
- Publication Date
- 2025-11-25
AI Technical Summary
Existing whitening skincare products cannot completely inhibit tyrosinase activity, resulting in melanin synthesis not being completely stopped. Especially under the attack of ultraviolet rays and free radicals, the whitening effect is not significant.
The formula combines Norway spruce leaf extract, Indian swert sprout extract, and heather extract. Through the synergistic effect of the active ingredients, it significantly inhibits tyrosinase activity, protects against ultraviolet rays, scavenges free radicals, and reduces melanin synthesis.
It significantly improves whitening effects, allows skin to breathe more freely, and promotes better skin health, without the need for a thick layer of UV protection.
Smart Images
Figure BDA0005639060870000071
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the field of skin care raw materials, in particular to a whitening composition and application thereof. BACKGROUND
[0002] Skin care products are products for skin care. With the progress of science and technology, skin care products are no longer luxury goods, but have become daily consumer goods for most beauty lovers. Among them, whitening is one of the most popular skin care functions. Existing whitening skin care products mainly achieve whitening effect by inhibiting melanin synthesis. However, the existing raw materials with tyrosinase activity cannot achieve 100% inhibition of tyrosinase, so they can only reduce the synthesis of melanin and cannot completely inhibit the synthesis of melanin. Under the persistent attack of ultraviolet rays and free radicals, cells will continue to stimulate the synthesis of melanin, resulting in insignificant whitening effect, which is difficult to meet the needs of consumers. Therefore, there is still room for improvement. SUMMARY
[0003] In order to further improve the whitening effect, the present application provides a whitening composition and application thereof.
[0004] In a first aspect, the present application provides a whitening composition, which adopts the following technical solution: A whitening composition, comprising the following components in mass fraction: 1.02-2.2 parts of a composite extract; 1.02-2.2 parts of a moisturizing agent; 0.002-0.02 parts of a preservative; 0.158-1.58 parts of a solvent; The composite extract is a compound of Norway spruce leaf extract, Indian rhizoma baulinophyllum extract and rhododendron extract.
[0005] By adopting the above technical solution, the composite extract composed of Norway spruce leaf extract, Indian rhizoma baulinophyllum extract and rhododendron extract can significantly inhibit the activity of tyrosinase under the cooperation of the active ingredients of each extract. At the same time, it can also resist ultraviolet rays, significantly reduce the attack of ultraviolet rays on cells, and effectively remove free radicals to reduce the attack of free radicals on skin. Through multiple synergies, the amount of melanin synthesis is reduced to a lower level, so that the whitening effect of skin is more significant, and the needs of consumers are better met. Moreover, since there is no need to add ingredients to physically block ultraviolet rays, the skin care product prepared from the composition does not need to cover a thick protective layer on the skin surface, so that the skin can breathe more smoothly, which is more conducive to skin health and better product experience.
[0006] Preferably, in the complex extract, the mass ratio of the Picea abies leaf extract, the Klamath weed extract and the Pittosporum tobira extract is 1-2:0.01-0.1:0.01-0.1.
[0007] By adopting the technical scheme, the mass ratio of the Picea abies leaf extract, the Klamath weed extract and the Pittosporum tobira extract is specifically selected, so that the active ingredients are combined in a specific ratio, the synergistic effect is more remarkable, and the significant whitening effect can be better exerted.
[0008] Preferably, the moisturizing agent is a combination of magnolia alcohol and butylene glycol.
[0009] By adopting the technical scheme, the addition of magnolia alcohol and butylene glycol makes the moisturizing effect better, the skin can be better cared for, the skin is healthier, and thus the skin can be more conducive to expelling melanin and assisting in improving the whitening effect.
[0010] Preferably, in the moisturizing agent, the mass ratio of the magnolia alcohol and the butylene glycol is 1-2:0.02-0.2.
[0011] By adopting the technical scheme, the mass ratio of the magnolia alcohol and the butylene glycol is specifically selected, and the moisturizing effect is more remarkable.
[0012] Preferably, the preservative is a combination of 1,2-hexanediol and p-hydroxyacetophenone.
[0013] By adopting the technical scheme, the specific selection of 1,2-hexanediol and p-hydroxyacetophenone makes the preservative effect better and the irritation lower, and the skin is more friendly.
[0014] Preferably, in the preservative, the mass ratio of the 1,2-hexanediol and the p-hydroxyacetophenone is 0.001-0.01:0.001-0.01.
[0015] By adopting the technical scheme, the mass ratio of the 1,2-hexanediol and the p-hydroxyacetophenone is specifically selected, and the preservative effect is better.
[0016] Preferably, the solvent is water.
[0017] By adopting the technical scheme, the specific selection of the solvent as water makes the solubility of each component in the solvent higher, the synergistic effect can be better exerted, and the skin is more easily absorbed.
[0018] In a second aspect, the application provides an application of a whitening composition, which adopts the following technical scheme: The application of the whitening composition described above, the whitening composition is added to a skin care product or a cosmetic formula to prepare a skin care product or a cosmetic with a whitening effect.
[0019] By adopting the above technical solutions, the skin care products or cosmetics produced can achieve a very significant whitening effect. They can effectively protect the skin, reduce the damage of ultraviolet rays and free radicals to cells, reduce the factors that increase melanin synthesis, and inhibit melanin synthesis, resulting in a smaller overall amount of melanin synthesis and thus a very significant whitening effect.
[0020] In summary, this application has the following beneficial effects: 1. Because this application uses a compound extract made from Norway spruce leaf extract, Indian swert sprout extract, and heather extract, the active ingredients of each extract work synergistically to significantly inhibit tyrosinase activity. It also effectively resists ultraviolet radiation, significantly reducing UV damage to cells, and effectively scavenges free radicals, reducing their damage to the skin. Through multi-component synergy, melanin synthesis is reduced to an even lower level, resulting in a more significant skin whitening effect, better meeting consumer needs. Furthermore, since no physical UV-blocking ingredients are required, the skincare products made from this composition do not need a thick protective layer on the skin surface, allowing for better skin respiration and promoting skin health, resulting in a superior user experience.
[0021] 2. In this application, the preferred method is to select the specific mass ratio of Norway spruce leaf extract, Indian spruce sprout extract, and broom photinia extract so that the active ingredients are combined in a specific ratio to exert a more significant synergistic effect and better achieve a significant whitening effect.
[0022] 3. In this application, the addition of magnolol and butylene glycol is preferred to improve the moisturizing effect, better care for the skin, make the skin healthier, and thus facilitate the skin to excrete melanin more quickly, thereby helping to improve the whitening effect. Detailed Implementation
[0023] The present application will be further described in detail below with reference to the embodiments.
[0024] Example 1 A whitening composition, prepared by the following method: Step 1): Add 1 kg of magnolol, 0.02 kg of butanediol, 0.001 kg of 1,2-hexanediol, 0.001 kg of p-hydroxyacetophenone, and 0.158 kg of deionized water into a stirred tank, heat to 50°C, stir at 60 r / min for 5 min until the mixture is homogeneous, and obtain the premix.
[0025] Step 2), cool the premix to 40℃, then add 1 kg of Norway spruce leaf extract, 0.01 kg of Indian clubmoss extract, 0.01 kg of Photinia serratifolia extract to the premix, stir at 60 r / min for 10 min, mix evenly, and obtain the whitening composition.
[0026] Magnolia alcohol is purchased from Hunan and Guangdong Biotechnology Co., Ltd.
[0027] Butanediol is purchased from Guangzhou Yezheng Biotechnology Co., Ltd.
[0028] 1,2-Hexanediol is purchased from Guangzhou Yezheng Biotechnology Co., Ltd.
[0029] 4-Hydroxyacetophenone is purchased from Guangzhou Yezheng Biotechnology Co., Ltd.
[0030] Norway spruce leaf extract is purchased from Norture Lights Cell Science Inc., water-soluble extract.
[0031] Indian clubmoss extract is purchased from Guangzhou Yezheng Biotechnology Co., Ltd., water-soluble extract.
[0032] Photinia serratifolia extract is purchased from Guangzhou Yezheng Biotechnology Co., Ltd., water-soluble extract.
[0033] Example 2 A whitening composition is prepared as follows: Step 1), put 1.5 kg of magnolia alcohol, 0.1 kg of butanediol, 0.005 kg of 1,2-hexanediol, 0.005 kg of 4-hydroxyacetophenone, and 0.79 kg of deionized water into a stirred tank, heat to 53℃, stir at 65 r / min for 7 min, mix evenly, and obtain a premix.
[0034] Step 2), cool the premix to 40℃, then add 1.5 kg of Norway spruce leaf extract, 0.05 kg of Indian clubmoss extract, and 0.05 kg of Photinia serratifolia extract to the premix, stir at 65 r / min for 11 min, mix evenly, and obtain the whitening composition.
[0035] Magnolia alcohol is purchased from Hunan and Guangdong Biotechnology Co., Ltd.
[0036] Butanediol is purchased from Guangzhou Yezheng Biotechnology Co., Ltd.
[0037] 1,2-Hexanediol is purchased from Guangzhou Yezheng Biotechnology Co., Ltd.
[0038] 4-Hydroxyacetophenone is purchased from Guangzhou Yezheng Biotechnology Co., Ltd.
[0039] Norway spruce leaf extract was purchased from Norture Lights Cell Science Inc., water-soluble extract.
[0040] Indian rhinacanthus extract was purchased from Guangzhou Yezhi Biotechnology Co., Ltd., water-soluble extract.
[0041] Ruscus extract was purchased from Guangzhou Yezhi Biotechnology Co., Ltd., water-soluble extract.
[0042] Example 3 A whitening composition was prepared as follows: Step 1), 2 kg of magnolia alcohol, 0.2 kg of butanediol, 0.01 kg of 1,2-hexanediol, 0.01 kg of p-hydroxyacetophenone, 1.58 kg of deionized water were put into a stirring kettle, heated to 55 ℃, the stirring speed was 70 r / min, stirred for 8 min, and mixed uniformly to obtain a premix.
[0043] Step 2), the premix was cooled to 40 ℃, then 2 kg of Norway spruce leaf extract, 0.1 kg of Indian rhinacanthus extract, and 0.1 kg of Ruscus extract were added to the premix, the stirring speed was 70 r / min, stirred for 12 min, and mixed uniformly to obtain a whitening composition.
[0044] Magnolia alcohol was purchased from Hunan and Guangdong Biotechnology Co., Ltd.
[0045] Butanediol was purchased from Guangzhou Yezhi Biotechnology Co., Ltd.
[0046] 1,2-hexanediol was purchased from Guangzhou Yezhi Biotechnology Co., Ltd.
[0047] P-hydroxyacetophenone was purchased from Guangzhou Yezhi Biotechnology Co., Ltd.
[0048] Norway spruce leaf extract was purchased from Norture Lights Cell Science Inc., water-soluble extract.
[0049] Indian rhinacanthus extract was purchased from Guangzhou Yezhi Biotechnology Co., Ltd., water-soluble extract.
[0050] Ruscus extract was purchased from Guangzhou Yezhi Biotechnology Co., Ltd., water-soluble extract.
[0051] Comparative Example 1 A whitening composition was prepared as follows: Step 1), 1.5 kg of magnolia alcohol, 0.1 kg of butanediol, 0.005 kg of 1,2-hexanediol, 0.005 kg of p-hydroxyacetophenone, and 0.79 kg of deionized water were put into a stirring kettle, heated to 53 ℃, the stirring speed was 65 r / min, stirred for 7 min, and mixed uniformly to obtain a premix.
[0052] Step 2), cool the premix to 40℃, then add 1.5 kg of Glycyrrhiza glabra extract, 0.05 kg of Kadsura indica extract, and 0.05 kg of Pittosporum tetraspermum extract to the premix, stir at 65 r / min for 11 min, mix uniformly, and obtain the whitening composition.
[0053] Magnolia alcohol is purchased from Hunan and Guangdong Biotechnology Co., Ltd.
[0054] Butanediol is purchased from Guangzhou Yezheng Biotechnology Co., Ltd.
[0055] 1,2-Hexanediol is purchased from Guangzhou Yezheng Biotechnology Co., Ltd.
[0056] 4-Hydroxyacetophenone is purchased from Guangzhou Yezheng Biotechnology Co., Ltd.
[0057] Glycyrrhiza glabra extract is purchased from Guangdong Mingtong Biotechnology Co., Ltd., water-soluble extract.
[0058] Kadsura indica extract is purchased from Guangzhou Yezheng Biotechnology Co., Ltd., water-soluble extract.
[0059] Pittosporum tetraspermum extract is purchased from Guangzhou Yezheng Biotechnology Co., Ltd., water-soluble extract.
[0060] The present comparative example is compared with Example 2, and the only difference is that: Glycyrrhiza glabra extract is used to replace the equivalent amount of Picea abies leaf extract.
[0061] Comparative Example 2 A whitening composition is prepared by the following method: Step 1), put 1.5 kg of Magnolia alcohol, 0.1 kg of butanediol, 0.005 kg of 1,2-hexanediol, 0.005 kg of 4-hydroxyacetophenone, and 0.79 kg of deionized water into a stirred tank, heat to 53℃, stir at 65 r / min for 7 min, mix uniformly, and obtain a premix.
[0062] Step 2), cool the premix to 40℃, then add 1.5 kg of Glycyrrhiza glabra extract, 0.05 kg of Kadsura indica extract, and 0.05 kg of Pittosporum tetraspermum extract to the premix, stir at 65 r / min for 11 min, mix uniformly, and obtain the whitening composition.
[0063] Magnolia alcohol is purchased from Hunan and Guangdong Biotechnology Co., Ltd.
[0064] Butanediol is purchased from Guangzhou Yezheng Biotechnology Co., Ltd.
[0065] 1,2-Hexanediol is purchased from Guangzhou Yezheng Biotechnology Co., Ltd.
[0066] p-Hydroxyacetophenone was purchased from Guangzhou Yewu Biotechnology Co., Ltd.
[0067] Norway spruce leaf extract was purchased from Norture Lights Cell Science Inc., water-soluble extract.
[0068] Gallnut extract was purchased from Xi'an Wuliang Biotechnology Co., Ltd., water-soluble extract.
[0069] Ruscus aculeatus extract was purchased from Guangzhou Yewu Biotechnology Co., Ltd., water-soluble extract.
[0070] The present comparative example is compared with Example 2, the only difference being that: Gallnut extract was used instead of Indian clubmoss extract.
[0071] Comparative Example 3 A whitening composition was prepared as follows: Step 1), 1.5 kg of magnolia alcohol, 0.1 kg of butanediol, 0.005 kg of 1,2-hexanediol, 0.005 kg of p-hydroxyacetophenone, and 0.79 kg of deionized water were added to a stirred tank, heated to 53°C, stirred at 65 r / min for 7 min, and mixed uniformly to obtain a premix.
[0072] Step 2), the premix was cooled to 40°C, then 1.5 kg of Norway spruce leaf extract, 0.05 kg of Indian clubmoss extract, and 0.05 kg of bearberry leaf extract were added to the premix, stirred at 65 r / min for 11 min, and mixed uniformly to obtain a whitening composition.
[0073] Magnolia alcohol was purchased from Hunan and Guangdong Biotechnology Co., Ltd.
[0074] Butanediol was purchased from Guangzhou Yewu Biotechnology Co., Ltd.
[0075] 1,2-Hexanediol was purchased from Guangzhou Yewu Biotechnology Co., Ltd.
[0076] p-Hydroxyacetophenone was purchased from Guangzhou Yewu Biotechnology Co., Ltd.
[0077] Norway spruce leaf extract was purchased from Norture Lights Cell Science Inc., water-soluble extract.
[0078] Indian clubmoss extract was purchased from Guangzhou Yewu Biotechnology Co., Ltd., water-soluble extract.
[0079] Bearberry leaf extract was purchased from Xi'an Tianfeng Biotechnology Co., Ltd., water-soluble extract.
[0080] The comparative example is compared with Example 2, the only difference being that: The bearberry leaf extract is used to replace the Photinia serratifolia extract in an equal amount.
[0081] Comparative Example 4 A whitening composition is prepared as follows: Step 1), 1.5 kg of magnolia alcohol, 0.1 kg of butanediol, 0.005 kg of 1,2-hexanediol, 0.005 kg of p-hydroxyacetophenone, and 0.79 kg of deionized water are put into a stirred tank, heated to 53℃, the stirring speed is 65 r / min, stirred for 7 min, and mixed uniformly to obtain a premix.
[0082] Step 2), the premix is cooled to 40℃, then 1.5 kg of glycyrrhiza glabra extract, 0.05 kg of gallnut extract, and 0.05 kg of bearberry leaf extract are added to the premix, the stirring speed is 65 r / min, stirred for 11 min, and mixed uniformly to obtain a whitening composition.
[0083] The magnolia alcohol is purchased from Hunan and Guangdong Biotechnology Co., Ltd.
[0084] The butanediol is purchased from Guangzhou Yezheng Biotechnology Co., Ltd.
[0085] The 1,2-hexanediol is purchased from Guangzhou Yezheng Biotechnology Co., Ltd.
[0086] The p-hydroxyacetophenone is purchased from Guangzhou Yezheng Biotechnology Co., Ltd.
[0087] The glycyrrhiza glabra extract is purchased from Guangdong Mingtong Biotechnology Co., Ltd., and is a water-soluble extract.
[0088] The gallnut extract is purchased from Xi'an Wuliang Biotechnology Co., Ltd., and is a water-soluble extract.
[0089] The bearberry leaf extract is purchased from Xi'an Tianfeng Biotechnology Co., Ltd., and is a water-soluble extract.
[0090] The comparative example is compared with Example 2, the only difference being that: The glycyrrhiza glabra extract is used to replace the Norway spruce leaf extract in an equal amount, the gallnut extract is used to replace the Indian rhizoma bupleuri extract in an equal amount, and the bearberry leaf extract is used to replace the Photinia serratifolia extract in an equal amount.
[0091] Experiment 1 The SPF value of the sample to be tested prepared from the whitening composition of each example and comparative example is determined according to the detection method of the sun protection index (SPF value) of sunscreen cosmetic in Chapter 8, Section 2 of the 2015 edition of the Cosmetics Safety Technical Specification.
[0092] The PFA value of the test sample prepared from each of the whitening compositions of the examples and the comparative examples was determined according to the detection method of the ultraviolet A wave (i.e., UVA) protection index (PFA value) in Chapter 8, Section 4 of the Cosmetic Safety Technical Specifications 2015 edition.
[0093] Each group of experiments was performed ten times, and the average value was taken.
[0094] Test sample: 1 g of the whitening composition was taken, 99 g of deionized water was added, and the mixture was uniformly mixed to obtain a test sample.
[0095] Experiment 2 The tyrosinase inhibition rate (%) of the test sample prepared from each of the whitening compositions of the examples and the comparative examples was detected according to T / GDCA 006-2021 Cosmetic Raw Material Inhibition Test Method for Tyrosinase Activity (In Vitro Method).
[0096] Each group of experiments was performed ten times, and the average value was taken.
[0097] Test sample: 1 g of the whitening composition was taken, 99 g of deionized water was added, and the mixture was uniformly mixed to obtain a test sample.
[0098] Experiment 3 The DPPH free radical scavenging rate (%) of the test sample prepared from each of the whitening compositions of the examples and the comparative examples was detected according to T / SHRH 006-2018 Cosmetics - Free Radical (DPPH) Scavenging Test Method.
[0099] Each group of experiments was performed ten times, and the average value was taken.
[0100] Test sample: 1 g of the whitening composition was taken, 99 g of deionized water was added, and the mixture was uniformly mixed to obtain a test sample.
[0101] The specific experimental data of experiments 1-3 are shown in Table 1.
[0102] Table 1 According to the comparison of the data of each of the examples and the comparative examples in Table 1, the SPF value, the PFA value, the tyrosinase inhibition rate (%), and the DPPH free radical scavenging rate (%) of each of the examples are significantly higher than those of the comparative examples. It can be seen that after the Norwegian spruce leaf extract, the Indian kyllinga extract, and the Photinia serratifolia extract in the examples are replaced by other plant extracts with whitening effect, the whitening effect on the skin is general, the effect of inhibiting melanin synthesis is not as good as that of the examples, the effect of preventing ultraviolet rays is significantly reduced, and the effect of clearing free radicals is also not good.
[0103] It is proved that only when the Norway spruce leaf extract, the Indian Swertia herb extract and the Pittosporum tobira extract are compounded, can the special synergistic effect be volatilized, so as to realize the comprehensive whitening effect inside and outside, and make the whitening effect very remarkable.
[0104] The embodiment is only an explanation of the present application, and is not a limitation of the present application, and those skilled in the art can make modifications to the embodiment without creative contribution according to the needs after reading the specification, but as long as the modifications are within the scope of the claims of the present application, they are protected by the patent law.
Claims
1. A whitening composition, characterized in that: The components include the following parts by mass: 1.02-2.2 parts of compound extract; Moisturizer 1.02-2.2 parts; Preservative 0.002-0.02 parts; Solvent: 0.158-1.58 parts; The compound extract is a combination of Norway spruce leaf extract, Indian swert extract, and broom photinia extract.
2. The whitening composition according to claim 1, characterized in that: In the compound extract, the mass ratio of Norway spruce leaf extract, Indian swert sprout extract, and broom photinia extract is 1-2:0.01-0.1:0.01-0.
1.
3. The whitening composition according to claim 1, characterized in that: The moisturizer is a combination of magnolol and butylene glycol.
4. The whitening composition according to claim 3, characterized in that: In the humectant, the mass ratio of magnolol to butylene glycol is 1-2:0.02-0.
2.
5. The whitening composition according to claim 1, characterized in that: The preservative is a combination of 1,2-hexanediol and p-hydroxyacetophenone.
6. The whitening composition according to claim 5, characterized in that: In the preservative, the mass ratio of 1,2-hexanediol to p-hydroxyacetophenone is 0.001-0.01:0.001-0.
01.
7. The whitening composition according to claim 1, characterized in that: The solvent is water.
8. The application of a whitening composition according to any one of claims 1-7, characterized in that: The whitening composition is added to skincare or cosmetic formulations to prepare skincare or cosmetic products with whitening effects.