Suprachoroidal space implant system

Abstract

The invention provides a suprachoroidal implant system which comprises a suprachoroidal implant and a conveyor, the suprachoroidal implant is of a porous structure and is used for being implanted into a suprachoroidal cavity, and aqueous humor is discharged from a gap between the suprachoroidal cavity and the sclera to reduce intraocular pressure; the conveyor is used for implanting a suprachoroidal cavity implant into a suprachoroidal cavity, the conveyor comprises a shell, a sheath tube assembly, an ejection piece and a pushing assembly, and the shell forms a handle part of the conveyor; the sheathing canal assembly is detachably arranged at the head end of the handle part and can store a suprachoroidal space implant; the ejection piece is fixed in the handle part along the longitudinal direction of the handle part; the ejection piece is at least partially arranged in the guide sheath tube in a penetrating manner and can act on the suprachoroidal implant; the pushing assembly is at least partially exposed out of the handle part and can act on the sheathing canal assembly to guide the guiding sheathing canal to move in the longitudinal direction of the handle part, so that the ejection piece can push the suprachoroidal cavity implant out of the guiding sheathing canal and implant the suprachoroidal cavity implant into the suprachoroidal cavity.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical equipment, in particular to a suprachoroidal implant system. BACKGROUND

[0002] Glaucoma is the leading irreversible blinding eye disease in the world, and with the aging of the population, the prevalence of glaucoma is increasing year by year. Intraocular pressure (IOP) is an independent risk factor for glaucoma, leading to further damage to the optic nerve of glaucoma. Controlling intraocular pressure is an economical approach. There are many types of current glaucoma surgery, such as laser therapy, trabeculectomy, implantation of various drainage devices and MIGS, etc. However, various surgical procedures or devices have certain limitations, such as short effective time of laser therapy, more postoperative complications of trabeculectomy, larger incision of general drainage device, and limited effect of MIGS on reducing intraocular pressure.

[0003] Suprachoroidal drainage is to implant a drainage device into the suprachoroidal space, expand the narrow suprachoroidal space, and increase the outflow of aqueous humor from the suprachoroidal space to reduce intraocular pressure. The structure and morphology of the current suprachoroidal drainage implant still need to be optimized to improve the fit of the implant with the sclera and choroid, enhance the bonding force and anti-displacement of the implant and eye tissue, and reduce the scar formation after implantation to avoid causing aqueous humor outflow passage blockage. In addition, the structure of the existing suprachoroidal implant delivery device is complex and the processing cost is high, which still needs to be improved and optimized. SUMMARY

[0004] To solve the above technical problems, the present application provides a suprachoroidal implant system, comprising: a suprachoroidal implant having a porous structure for implanting into a suprachoroidal space to drain aqueous humor from the suprachoroidal space between the choroid and the sclera to reduce intraocular pressure; the suprachoroidal implant comprises an implant body, the implant body comprises a proximal end, a distal end and an intermediate part in the longitudinal direction, the proximal end is the end close to the anterior chamber after the implant is implanted into the eye, the lower surface of the implant body is a plane, the upper surface of the implant body is at least partially curved, and the thickness of at least the distal end to the intermediate part of the implant body gradually increases; a delivery device for implanting the suprachoroidal implant into the suprachoroidal space, wherein the delivery device comprises: a housing forming a handle portion of the delivery device; a sheath assembly detachably arranged at the leading end of the handle portion; the sheath assembly has a guide sheath capable of storing the suprachoroidal implant; an ejector fixed inside the handle portion along the longitudinal direction of the handle portion; the ejector is at least partially inserted into the guide sheath and can act on the suprachoroidal implant; a pushing assembly at least partially exposed to the handle portion, capable of acting on the sheath assembly to guide the guide sheath to move along the longitudinal direction of the handle portion, so that the ejector can push the suprachoroidal implant out of the guide sheath and implant it into the suprachoroidal space.

[0005] The present application provides a suprachoroidal implant system, comprising a suprachoroidal implant and a delivery device, the suprachoroidal implant having a porous structure for implanting into a suprachoroidal space to drain aqueous humor from the suprachoroidal space between the choroid and the sclera to reduce intraocular pressure; the delivery device for implanting the suprachoroidal implant into the suprachoroidal space, the delivery device comprising a housing, a sheath assembly, an ejector and a pushing assembly, the housing forming a handle portion of the delivery device; the sheath assembly detachably arranged at the leading end of the handle portion, capable of storing the suprachoroidal implant; the ejector fixed inside the handle portion along the longitudinal direction of the handle portion; the ejector is at least partially inserted into the guide sheath and can act on the suprachoroidal implant; the pushing assembly at least partially exposed to the handle portion, capable of acting on the sheath assembly to guide the guide sheath to move along the longitudinal direction of the handle portion, so that the ejector can push the suprachoroidal implant out of the guide sheath and implant it into the suprachoroidal space. BRIEF DESCRIPTION OF DRAWINGS

[0006] In order to more clearly illustrate the technical solutions in the embodiments of the application, the following will briefly introduce the drawings needed to be used in the embodiment description. Obviously, the drawings in the following description are only some embodiments of the application, and for those skilled in the art, other drawings can also be obtained from these drawings without creative labor. FIG. 1Ais a side view of one embodiment of an implant of the suprachoroidal implant system of the present invention; FIG. 1B is a side view of another embodiment of an implant of the suprachoroidal implant system of the present invention; FIG. 1C is a top view of one embodiment of an implant of the suprachoroidal implant system of the present invention; FIG. 1D is a side view of another embodiment of an implant of the suprachoroidal implant system of the present invention; FIG. 2A is a perspective view of a delivery device of the suprachoroidal implant system of the present invention; FIG. 2B is a perspective view of a delivery device of the suprachoroidal implant system of the present invention after removal of a second housing portion; FIG. 2C is a perspective view of a first housing portion of a delivery device of the suprachoroidal implant system of the present invention; FIG. 2D is an exploded view of a sheath assembly of a delivery device of the suprachoroidal implant system of the present invention; FIG. 2E is a perspective view of a guide sheath of a delivery device of the suprachoroidal implant system of the present invention; FIG. 2F is a perspective view of a package of a delivery device of the suprachoroidal implant system of the present invention; FIG. 2G is a perspective view of a reservoir of a delivery device of the suprachoroidal implant system of the present invention; FIG. 2H is a perspective view of a delivery device of the suprachoroidal implant system of the present invention after application of a protective cap; FIG. 2I is a perspective view of a delivery device of the suprachoroidal implant system of the present invention after removal of a sheath assembly; FIG. 2J is a perspective view of a push button of a delivery device of the suprachoroidal implant system of the present invention; FIG. 2K is a perspective view of a sheath drive element of a delivery device of the suprachoroidal implant system of the present invention; FIG. 2L is a perspective view of an unlock element of a delivery device of the suprachoroidal implant system of the present invention; FIG. 3A is a perspective view of a delivery device of the suprachoroidal implant system of the present invention after removal of a second housing portion of another embodiment; FIG. 3B is a perspective view of a first housing portion of a delivery device of the suprachoroidal implant system of the present invention of another embodiment; FIG. 3Cis a perspective view of a sheath assembly and an ejector of another embodiment of the delivery device in the suprachoroidal implant system of the present application; FIG. 3D is a perspective view of an unlocking element of another embodiment of the delivery device in the suprachoroidal implant system of the present application; FIG. 4A is a perspective view of another embodiment of the delivery device in the suprachoroidal implant system of the present application before implantation; FIG. 4B is a perspective view of another embodiment of the delivery device in the suprachoroidal implant system of the present application after removal of the sheath assembly; FIG. 4C is an exploded view of another embodiment of the delivery device in the suprachoroidal implant system of the present application; FIG. 4D is a perspective view of a first housing part of another embodiment of the delivery device in the suprachoroidal implant system of the present application; FIG. 4E is a perspective view of another embodiment of the delivery device in the suprachoroidal implant system of the present application after application of a protective cap; FIG. 5 is a schematic view of an implantation site of a suprachoroidal implant in the suprachoroidal implant system of the present application. DETAILED DESCRIPTION

[0007] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments of the present application. Based on the embodiments in the present application, all other alternative embodiments obtained by a person of ordinary skill in the art without creative effort fall within the scope of the present application.

[0008] The present application provides a suprachoroidal implant system, which comprises a suprachoroidal implant and a delivery device, wherein the suprachoroidal implant has a porous structure and can discharge aqueous humor from the suprachoroidal space between the choroid and the sclera to reduce intraocular pressure after being implanted in the suprachoroidal space of a human eye; and the delivery device can stably and accurately implant the suprachoroidal implant in the suprachoroidal space of a human eye.

[0009] The embodiments of the suprachoroidal implant and the delivery device in the present application will be described below respectively.

[0010] Embodiment one of the suprachoroidal implant Please refer to FIGS. 1A-1C and FIG. 5 , FIGS. 1A-1C is a structural schematic view of the suprachoroidal implant, FIG. 5A schematic diagram of a suprachoroidal space implant implanted in the suprachoroidal space. As an embodiment of the suprachoroidal space implant, the suprachoroidal space implant has a porous structure, and after being implanted in the suprachoroidal space, aqueous humor can flow through the pores of the porous structure, thereby draining the aqueous humor in the suprachoroidal space between the choroid and the sclera to reduce intraocular pressure; more specifically, the suprachoroidal space implant includes an implant body a1, which includes a proximal end a101, a distal end a103 and an intermediate portion a102 in the longitudinal direction (i.e. the length direction), wherein the proximal end a101 is the end close to the anterior chamber after the implant is implanted in the eye, and the distal end a103 is the end away from the anterior chamber after the implant is implanted in the eye; the lower surface a3 of the implant body a1 is planar, and the upper surface a2 of the implant body is at least partially arc-shaped, and the thickness of at least the distal end a103 to the intermediate portion a102 of the implant body a1 gradually increases.

[0011] As shown in FIG. 1A In this embodiment, the lower surface a3 of the implant body a1 is planar as a whole, which can make the contact area between the implant body a1 and the choroid a100 larger, and the upper surface a2 is at least arc-shaped from the distal end a103 to the intermediate portion a102, which is beneficial for the stable adhesion of the implant on the choroid a100, and the upper surface a2 and the lower surface a3 of the implant body a1 can be stably fixed in the suprachoroidal space a300 under the clamping of the sclera a200 and the choroid a100, reducing the risk of displacement of the implant body a1 to the anterior chamber and the choroid, avoiding exposure to the anterior chamber, and minimizing the risk of corneal endothelial cell loss.

[0012] In this embodiment, the lower surface a3 of the implant body a1 is planar, and the upper surface a2 can be formed as an arched arc surface, and the thickness of the distal end to the intermediate portion a102 of the implant body a1 gradually increases, i.e. the upper surface a2 of the implant body is formed by connecting a semiarched arc surface to a planar surface; in some embodiments, the thickness of the distal end a103 and the proximal end a101 to the intermediate portion a102 of the implant body a1 gradually increases.

[0013] In this embodiment, the material of the suprachoroidal space implant is prepared from porous silicone, porous polyethylene or porous TPU, with a pore size of 10-60 μm and a porosity of 30-70%, which can enhance the bonding force between the implant and the eye tissue, and on the other hand, part of the aqueous humor can also flow through the pores, improving the drainage effect.

[0014] As shown in FIG. 1B and FIG. 1CAs shown, in the present embodiment, the length L of the implant body a1 is set in the range of 4-8 mm, the width W of the implant body a1 in the transverse direction is preferably 0.8-1.8 mm; the maximum thickness H1 of the implant body a1 from the upper surface a2 to the lower surface a3 is 0.4-1.2 mm; preferably, the minimum thickness H2 of the implant body a1 from the upper surface a2 to the lower surface a3 is 0.2-0.6 mm.

[0015] Further, in order to consider different populations and the severity of glaucoma, implant bodies a1 of different sizes can be prepared, for example, the length L of the implant body a1 can be selected as 4 mm, 4.5 mm, 5 mm, 5.5 mm, 6 mm, 6.5 mm, 7 mm, 7.5 mm and 8 mm; the width W can be selected as 0.8 mm, 1 mm, 1.2 mm, 1.4 mm, 1.6 mm, 1.8 mm; the maximum thickness H1 can be selected as 0.4 mm, 0.6 mm, 0.8 mm, 1.0 mm, 1.2 mm, etc., and the minimum thickness H2 can be selected as 0.2 mm, 0.3 mm, 0.4 mm, 0.5 mm, 0.6 mm. For example, in some embodiments, the length L of the implant body a1 is 4 mm, the width is 0.8 mm, the maximum thickness H1 is 0.4 mm, and the minimum thickness H2 is 0.2 mm; in some embodiments, the length L of the implant body a1 is 6 mm, the width is 1.2 mm, the maximum thickness H1 is 0.8 mm, and the minimum thickness H2 is 0.4 mm; in some embodiments, the length L of the implant body a1 is 8 mm, the width is 1.8 mm, the maximum thickness H1 is 1.2 mm, and the minimum thickness H2 is 0.6 mm.

[0016] Further, in order to control the implantation depth of the suprachoroidal implant in the eye and facilitate observation of the position of the suprachoroidal implant, as shown in FIG. 1B and FIG. 1D As shown, in some embodiments, the surface of the proximal end a101 has a display mark a104 adjacent to the proximal end surface of the proximal end a101, the width of the display mark a104 is 0.4-0.5 mm, and the length of the proximal end a101 for implantation into the anterior chamber is 0-0.5 mm.

[0017] As shown in FIG. 1B In the present embodiment, the display mark a104 is spaced apart from the proximal end surface of the proximal end a101, the distance between the distal most side of the display mark a104 and the proximal end surface of the proximal end a101 is 0.7-1 mm, preferably 0.7 mm, and the width of the display mark a104 is 0.4 mm, That is, the distance between the nearest side of the display mark a104 and the proximal end face of the proximal end a101 is 0.3 mm; when the proximal end a101 enters the anterior chamber, the part that enters the anterior chamber is preferably in the middle position of the display mark a104, at which time the distance L1 between the display mark a104 and the proximal end face of the proximal end a101 is 0.5 mm.

[0018] like FIG. 1D As shown, in some embodiments, the distance between the nearest side of the display mark a104 and the proximal end face of the proximal end a101 is 0, and the width of the display mark a104 is 0.5 mm, that is, the distance between the farthest side of the display mark a104 and the proximal end face of the proximal end a101 is 0.5 mm. When the proximal a101 enters the anterior chamber, it is sufficient that the display marker a104 can also enter the anterior chamber; the implantation depth is 0~0.5mm, meaning it can be placed at any position on the display marker a104. Similarly... FIG. 1C The implant shown can also be positioned at other locations on the display mark a104, ensuring that the depth of the proximal end a101 entering the anterior chamber is 0~0.5mm.

[0019] In this embodiment, the suprachoroidal implant is stored in the guide sheath 21 before implantation, and its position can be viewed through the observation window 214 on the guide sheath 21 by the display mark a104; on the other hand, during the implantation of the suprachoroidal implant into the eye, the depth of the proximal end a101 into the anterior chamber can be observed by setting the display mark a104, and the length of the proximal end a101 into the anterior chamber is kept at 0~0.5mm.

[0020] Conveyor 100 Example 1 Please see FIGS. 2A-2L The delivery device 100 is used to implant the aforementioned suprachoroidal implant into the suprachoroidal cavity. The delivery device 100 includes a housing, a sheath assembly 20, an ejector 30, and a pusher assembly 40. The housing forms the handle portion 10 of the delivery device 100 for easy gripping by the operator. The sheath assembly 20 is detachably disposed at the head end of the handle portion 10. The sheath assembly 20 has a guide sheath 21 capable of storing the suprachoroidal implant. The ejector 30 is fixed to the interior of the handle portion 10 along the longitudinal direction and is at least partially inserted into the guide sheath 21, capable of acting on the suprachoroidal implant. The pusher assembly 40 is at least partially exposed outside the handle portion 10 and can act on the sheath assembly 20 to guide the guide sheath 21 to move along the longitudinal direction of the handle portion 10, so that the ejector 30 can push the suprachoroidal implant out of the guide sheath 21 and implant it into the suprachoroidal cavity.

[0021] In this embodiment, the suprachoroidal implant is pre-stored at the second end of the guide sheath 21 (i.e., the end away from the handle portion 10), and a portion of the ejector 30 is inserted into the guide sheath 21. When the delivery device 100 is in use, the operator guides the guide sheath 21 to move longitudinally toward the handle portion 10 towards the interior of the handle portion 10 via the push assembly 40 (i.e., the guide sheath 21 slides toward the interior of the handle portion 10 along the ejector 30). During the movement, the guide sheath 21 causes the suprachoroidal implant to gradually come into contact with the ejector 30, and the guide sheath 21 moves further toward the interior of the handle portion 10. The suprachoroidal implant is pushed out of the guide sheath 21 by the ejector 30.

[0022] like FIG. 2D and FIG. 2F As shown, the sheath assembly 20 is detached from the handle portion 10 when not in use, and is installed on the handle portion 10 when in use. To enable a detachable connection between the sheath assembly 20 and the push assembly 40, the sheath assembly 20 also includes a head end connector 22, through which the sheath assembly 20 is detachably connected to the push assembly 40; the first end of the guide sheath 21 is fixedly connected to the head end connector 22, and the second end of the guide sheath 21 extends away from the handle portion 10.

[0023] Specifically, in FIG. 2D In the process, the head-end connector 22 includes a head-end coupling 221 and a sheath fixing member 222. The head-end coupling 221 has a cylindrical structure and is detachably connected to the handle portion 10 to achieve relative fixation with the handle portion 10. The head-end coupling 221 has a through hole 2211 on the side away from the handle portion 10 for the guide sheath 21 to pass through, and the first end of the guide sheath 21 passes through the through hole 2211. The sheath fixing member 222 is disposed in the cavity of the head-end coupling 221, and the outer contour of the sheath fixing member 222 is [not specified]. The size is larger than the diameter of the through hole 2211, so that the sheath fixation member 222 stops in the through hole 2211; one end of the sheath fixation member 222 is fixedly connected to the first end of the guide sheath 21, and the other end of the sheath fixation member 222 is detachably connected to the push assembly 40. After the sheath fixation member 222 is connected to the push assembly 40, under the drive of the push assembly 40, the sheath fixation member 222 can guide the guide sheath 21 to move along the longitudinal direction of the handle part 10, so that the suprachoroidal implant is pushed out of the guide sheath 21 under the push of the ejector 30.

[0024] Furthermore, in FIG. 2DIn the embodiment, the head end connecting piece 221 is provided with a plurality of connecting buckles 2212 around the side close to the handle part 10, and the handle part 10 is internally provided with connecting card slots 13 matched with the connecting buckles 2212; when the sheath pipe assembly 20 is installed, the connecting buckles 2212 of the head end connecting piece 221 are delivered to the inside of the handle part 10 and are inserted and fixed with the connecting card slots 13; when the sheath pipe assembly 20 is disassembled, the head end connecting piece 221 is pulled to make the connecting buckles 2212 disengage from the connecting card slots 13. In other embodiments, the head end connecting piece 221 can also be detachably connected with the handle part 10 through thread connection or magnetic attraction or other ways.

[0025] Further, in the embodiment, FIG. 2D In the embodiment, the sheath pipe fixing piece 222 is in a whole cylinder structure, and has a sheath pipe fixing slot 2221 in the axial direction, and the first end of the guide sheath pipe 21 is inserted and fixed in the sheath pipe fixing slot 2221; the end of the sheath pipe fixing piece 222 close to the handle part 10 is detachably connected with the pushing assembly 40. Specifically, the end of the sheath pipe fixing piece 222 close to the handle part 10 is provided with a plurality of protruding connecting parts 2222, which are detachably connected with the pushing assembly 40 through clamping. In other embodiments, the sheath pipe fixing piece 222 can be detachably connected with the pushing assembly 40 through thread connection or other ways.

[0026] Further, as shown in the embodiment, FIG. 2E The guide sheath pipe 21 has a guide cavity 213 in the axial direction, so that the suprachoroidal space implant can be pre-stored in the guide cavity 213, and the ejector 30 is in an elongated shaft structure, and a part of the ejector 30 is inserted in the guide cavity 213.

[0027] In the embodiment, in order to facilitate the observation of the implantation position and depth of the suprachoroidal space implant, the guide sheath pipe 21 is provided with an observation window 214 communicated with the guide cavity 213, and the observation window 214 extends from the second end to the first end of the guide sheath pipe 21, so that the operator can observe the suprachoroidal space implant through the observation window 214; during the implantation of the suprachoroidal space implant in the eye, the operator can observe the implantation position of the suprachoroidal space implant through the observation window 214, so that the implantation depth (for example, the depth of implantation in the anterior chamber) of the suprachoroidal space implant can be accurately controlled.

[0028] Further, in order to make the guide sheath pipe 21 adapt to eyes with different curvature radii, the material of the guide sheath pipe 21 is configured as a memory alloy material, so that the guide sheath pipe 21 can repeatedly deform. Preferably, the material of the guide sheath pipe 21 is a nickel-titanium alloy material.

[0029] In the embodiment, the guide sheath 21 comprises a straight sheath portion 211 and a curved sheath portion 212 in the axial direction of the guide sheath 21, wherein one end of the straight sheath portion 211 is fixed with the sheath fixing member 222, and the other end is connected with the curved sheath portion 212; the curved sheath portion 212 is close to the second end of the guide sheath 21, and the curved sheath portion 212 can be repeatedly bent into a linear structure parallel to the straight sheath portion 211 or a curved structure in the shape of a circular arc, so that the curved sheath portion 212 can be self-adapted to the curvature radius of the eye after being inserted into the eye.

[0030] In the embodiment, in order to make the curved sheath portion 212 more easily deformed, the pipe wall of the curved sheath portion 212 is provided with open grooves 215 in communication with the guide cavity 213 in the circumferential direction, and the open grooves 215 are arranged in an array in the axial direction of the curved sheath portion 212, so that the flexibility of the curved sheath portion 212 is better.

[0031] Further, in order to prevent the suprachoroidal space implant pre-existing in the guide sheath 21 from being separated from the end of the curved sheath portion 212 (i.e. the second end of the guide sheath 21), the end of the curved sheath portion 212 is further provided with two clamping claws 216, the two clamping claws 216 are oppositely arranged, and at least one clamping claw 216 is closed towards the axial direction of the curved sheath portion 212, so that the suprachoroidal space implant is limited in the guide cavity 213 in the non-implantation state; in the implantation state, the suprachoroidal space implant acts on the clamping claw 216 under the abutting of the ejector 30, so that the clamping claw 216 is deformed, and then the suprachoroidal space implant is pushed out of the guide cavity 213 from the limitation of the clamping claw 216.

[0032] In some embodiments, the center line of one of the clamping claws 216 is parallel to the axis of the curved sheath portion 212, and the other clamping claw 216 is closed towards the axis of the curved sheath portion 212 and abuts against the above-mentioned clamping claw 216; in some embodiments, both of the clamping claws 216 are closed towards the axis of the curved sheath portion 212 and abut against each other.

[0033] Further, as shown in FIG. 2F and FIG. 2G , the suprachoroidal space implant and the sheath assembly 20 are also stored separately before use; the suprachoroidal space implant system further comprises an encapsulating body 60, the encapsulating body 60 comprises a liquid storage container 61 and a sealing member (not shown in the figure), the liquid storage container 61 stores a holding liquid, the suprachoroidal space implant is installed in the guide sheath 21 before use, and is stored in the holding liquid together with the sheath assembly 20, and the sealing member seals the liquid storage container 61 to prevent the holding liquid from leaking; when the suprachoroidal space implant and the sheath assembly 20 are used, the sealing member is opened, the handle portion 10 is connected with the sheath assembly 20, and then the sheath assembly 20 is taken out of the holding liquid.

[0034] In the embodiment, the holding liquid can be sterile normal saline or an organic solvent or the like liquid; the sheath assembly 20 and the suprachoroidal implant are packaged in the holding liquid to keep the suprachoroidal implant sterile and moisture loss-free, and to avoid affecting the drainage effect of the suprachoroidal implant due to drying. At the same time, the design of the observation window 214 and the open slot 215 on the guide sheath 21 is also conducive to the holding liquid entering the guide sheath to fully moisten the suprachoroidal implant.

[0035] As shown in FIG. 2G , the liquid storage container 61 has a liquid storage cavity, and the holding liquid is stored in the liquid storage cavity; in order to realize the positioning of the sheath assembly 20, the inner wall of the liquid storage cavity is circumferentially provided with a plurality of head support arms 611, and the top of each head support arm 611 is provided with a clamping groove 612 matched with the head end connecting piece 221. When the sheath assembly 20 is placed in the liquid storage cavity, the head end connecting piece 221 is inserted and fixed in the clamping groove 612, so as to prevent the sheath assembly 20 from being displaced in the circumferential and axial directions after being placed in the liquid storage cavity.

[0036] Preferably, the sealing member can be a sealing cover movably connected with the liquid storage container 61, or a rubber plug or an aluminum foil.

[0037] Further, as shown in FIG. 2H and FIG. 2I , since the handle portion 10 is separated from the sheath assembly 20 before use, the ejector 30 is exposed to the handle portion 10. In order to realize the protection of the ejector 30, the suprachoroidal implant system further comprises a protective cap 70; the protective cap 70 is detachably connected with the handle portion, and can be arranged around the part of the ejector 30 exposed to the handle portion 10 to realize the protection of the ejector 30; the handle portion 10 can be removed when used.

[0038] Further, as shown in FIG. 2J and FIG. 2K , the push assembly 40 at least comprises a push button 41 and a sheath transmission element 42, wherein the push button 41 is at least partially exposed to the handle portion 10, so that the operator can operate the push button 41; the sheath transmission element 42 is slidingly arranged in the handle portion 10, one end of the sheath transmission element 42 is detachably connected with the sheath assembly 20, and the sheath transmission element 42 can be driven by the push button 41 to guide the guide sheath 21 to move along the longitudinal direction of the handle portion 10.

[0039] Specifically, as shown in FIG. 2JAs shown, the push button 41 includes a push part 411, a connecting part 412, and a driving part 413. The push part 411 is exposed outside the handle part 10, the driving part 413 is located inside the handle part 10, and the connecting part 412 connects the push part 411 and the driving part 413 in the vertical direction. The driving part 413 has a plate-like structure, and a first transmission tooth 4131 is provided at its bottom in the longitudinal direction.

[0040] Furthermore, the inner wall of the handle portion 10 is provided with a movable slide groove adapted to the drive portion 413. There are two movable slide grooves, which are symmetrically distributed on the two inner walls of the handle portion 10 in the transverse direction (i.e., the width direction of the handle portion 10, which is perpendicular to the longitudinal direction). The two ends of the drive portion 413 in the transverse direction are respectively inserted into a movable slide groove.

[0041] Preferred, in FIG. 2C In this design, the inner wall of the handle portion 10 has two movable support portions 14 in the vertical direction, and the gap between the two movable support portions 14 forms the aforementioned movable groove. To reduce the force required for the operator to move the push button 41, a plurality of protruding ribs 141 are also provided in the longitudinal direction on the inner side of the movable support portion 14 adjacent to the transmission portion 422. The protruding ribs 141 and the transmission portion 422 form line contact, reducing the resistance of the transmission portion 422 in moving within the movable groove. In some embodiments, the inner side of the movable support portion 14 and the drive portion 413 are in surface contact.

[0042] Furthermore, such as FIG. 2K As shown, the sheath drive element 42 includes a delivery section 421, a transmission section 422, and a limiting section 423 in the longitudinal direction; wherein, the delivery section 421 has a delivery channel 4211 in the axial direction, through which the ejector 30 passes; a fixing section 4212 is provided on the side of the delivery section 421 away from the transmission section 422, and the sheath drive element 42 is connected to the transmission section 422 via the fixing section 4212. FIG. 2D The connecting portion 2222 of the sheath fixing member 222 is detachably connected. Preferably, the fixing portion 4212 is an annular protrusion provided circumferentially along the delivery portion 421, and the annular protrusion can engage with the connecting portion 2222 of the sheath fixing member 222.

[0043] The transmission section 422 has an inverted gate-shaped structure, including a front transmission plate 4221, a middle transmission plate 4222, and a rear transmission plate 4223. The front transmission plate 4221 and the rear transmission plate 4223 are respectively disposed at both ends of the middle transmission plate 4222. A second transmission tooth 4224 is disposed on the top of the middle transmission plate 4222. FIG. 2C In the middle, the handle part 10 is provided with a plurality of sliding support parts 15 along the longitudinal direction to support the bottom of the intermediate transmission plate 4222. Preferably, the sliding support parts 15 have two rows, which support the two sides of the bottom of the intermediate transmission plate 4222 respectively.

[0044] Preferably, the bottom of the intermediate transmission plate 4222 is provided with a partition 4225, which partitions the bottom of the intermediate transmission plate 4222 into two parts, and the two parts are respectively supported on the corresponding sliding support 15.

[0045] Further, as shown in FIG. 2B , the pushing assembly 40 further comprises a rotating gear 43, which is drivingly connected between the pushing button 41 and the sheath transmission element 42, and in FIG. 2C , the inside of the handle part 10 is correspondingly provided with a fixed shaft 16, and the rotating gear 43 is arranged on the fixed shaft 16 and can rotate around the fixed shaft 16; specifically, the rotating gear 43 is engaged with the first transmission gear 4131 of the driving part 413 and the second transmission gear 4224 of the intermediate transmission plate 4222, and when the pushing button 41 slides forward along the longitudinal direction of the handle part 10, the rotating gear 43 rotates and acts on the transmission part 422, so that the intermediate transmission plate 4222 moves to the rear of the handle part 10, and the delivery part 421 pulls the guide sheath 21 to move rearward, and the suprachoroidal space implant is exposed from the guide sheath 21 under the abutting of the ejector 30.

[0046] In the embodiment, as shown in FIG. 2K , the limiting part 423 is a rod-shaped structure, and its cross section is circular; in FIG. 2C , the inside of the handle part 10 is further provided with a plurality of limiting plates 17 in the longitudinal direction, and the limiting plates 17 are provided with limiting holes 171 through which the limiting part 423 passes.

[0047] Further, in combination with FIG. 2B , FIG. 2C and FIG. 2L , in order to prevent the operator from misoperation, the conveyor 100 also has an anti-misoperation function; specifically, the conveyor 100 further comprises an unlocking element 50, which acts on the pushing assembly 40, and when the unlocking element 50 is in a locked state, it limits the movement of the pushing assembly 40 along the longitudinal direction of the handle part 10; when the unlocking element 50 is in an unlocked state, it allows the pushing assembly 40 to move along the longitudinal direction of the handle part 10.

[0048] In the embodiment, the unlocking element 50 is arranged between two adjacent limiting plates 17 and can move in the vertical direction of the handle part 10; the unlocking element 50 is provided with an unlocking channel 521, and when the unlocking element 50 is in a locked state, the unlocking channel 521 is out of position with the limiting hole 171, and the unlocking element 50 stops the limiting part 423 from moving in the longitudinal direction of the handle part 10; pressing the unlocking element 50 to move it towards the inside of the handle part 10, at this time the unlocking element 50 is unlocked, the unlocking channel 521 is coaxial with the limiting hole 171, and the limiting part 423 can move in the longitudinal direction of the handle part 10.

[0049] Specifically, the unlocking element 50 includes a pressing part 51 and a locking part 52 in the vertical direction, the pressing part 51 is exposed to the handle part 10 to facilitate the operator to trigger; the locking part 52 is a hollow structure, the unlocking channel 521 longitudinally penetrates the locking part 52, the side through holes 522 are arranged on the opposite two side walls of the locking part 52, the unlocking element 50 further has a deformation arm 523, one deformation arm 523 is arranged in each side through hole 522, the outer side of the deformation arm 523 has a first clamping block 5231, the second clamping block 18 corresponding to the first clamping block 5231 is arranged on the inner wall of the handle part 10; when the unlocking element 50 is pressed to move towards the inside of the handle part 10, the deformation arm 523 is deformed to move towards the inner wall of the locking part 52, the first clamping block 5231 and the second clamping block 18 are clamped and locked, and the movement of the unlocking element 50 towards the outside of the handle part 10 is hindered.

[0050] In the embodiment, the locking part 52 has four side walls, the side through holes 522 are arranged on the opposite two side walls, and the unlocking channel 521 penetrates the other two side walls.

[0051] In addition, in the embodiment, the push button 41 in the push assembly 40 is at the rear side of the handle part 10 in the initial state and cannot move towards the rear side of the handle part 10 due to the limitation of the shell; at the same time, the push button 41 cannot move towards the front side of the handle part 10 due to the limitation of the unlocking element 50, that is, the push button 41 cannot move in the front-rear direction of the handle part 10; when the unlocking element 50 is in the unlocked state, the push button 41 can only move towards the front side of the handle part 10, thereby pushing the limiting part 423 to move rearward.

[0052] Further, as shown in FIG. 2B and FIG. 2C In order to fix the end of the ejector 30, the conveyor 100 further has an ejector fixing block 80, the end of the ejector 30 is fixed to the ejector fixing block 80, the ejector fixing block 80 has a fixing slot 81 on the two sides in the transverse direction, the inside of the handle part 10 is further provided with a fixing frame 19, the fixing frame 19 is in the shape of an I-beam, the ejector fixing block 80 can be inserted and fixed on the fixing frame 19 through the fixing slot 81.

[0053] Further, in the embodiment, the shell includes the first shell part 11 and the second shell part 12 which are symmetrical to each other, the first shell part 11 and the second shell part 12 are detachably connected, thereby facilitating the assembly of the entire conveyor 100.

[0054] Conveyor 100 embodiment two As shown in FIGS. 3A-3DAs shown, as another embodiment of the conveyor 100, the difference from the first embodiment of the conveyor 100 described above includes the different structural compositions of the head-end connector 221, the ejector 30, and the unlocking element 50 in this embodiment.

[0055] Specifically, such as FIG. 3C As shown, in this embodiment, to enhance the stability of the connection between the head-end connector 221 and the handle portion 10, the head-end connector 221 has at least two connecting arms 2213 on the side near the handle portion 10. The two connecting arms 2213 are distributed circumferentially along the head-end connector 221, preferably symmetrically. The connecting arms 2213 extend away from the guide sheath 21, and the outer wall of the connecting arms 2213 also has a connecting buckle 2212. FIG. 3B In the handle portion 10, at least two limiting strips 101 adapted to the connecting buckle 2212 are provided inside the head end. The two limiting strips 101 are located on opposite sides of the inner wall of the handle portion 10, so that when the sheath assembly 20 is installed, the connecting buckle 2212 can slide along the limiting strip 101 and engage with the end of the limiting strip 101; when the sheath assembly 20 is disassembled, the head end connector 221 is pulled to disengage the connecting buckle 2212 from the limitation of the limiting strip 101.

[0056] Furthermore, to improve the coaxiality of the sheath fixing member 222 when moving the guide sheath 21 and enhance the stability of movement, in this embodiment, the cross-section of the connecting arm 2213 is an elongated arc shape. The circumferential diameter of the inner arc of the cross-section of the connecting arm 2213 is adapted to the outer diameter of the sheath fixing member 222, allowing the sheath fixing member 222 to slide along the inner wall of the connecting arm 2213 without radial displacement. Other structural parts of the head-end connector 221 are described in Embodiment 1 of the conveyor 100 above and will not be repeated here.

[0057] Furthermore, in this embodiment, the fixing method of the ejector 30 is different from that of the first embodiment of the conveyor 100 described above, such as... FIG. 3C As shown, the end of the ejector 30 has a protruding mounting portion 31. FIG. 3A and FIG. 3B In the middle, the inner wall of the handle part 10 is provided with a mounting sleeve 102 that is adapted to the mounting part 31, and the mounting part 31 is fixed in the mounting sleeve 102 by plugging.

[0058] Furthermore, such as FIG. 3A As shown, the drive part 413 in the push button 41 is in surface contact with the sliding groove on the inner wall of the handle part 10, that is, the inner side of the moving support part 14 is in surface contact with the drive part 413.

[0059] Furthermore, such as FIG. 3DAs shown, the unlocking element 50 includes a pressing part 51 and a locking part 52 in the vertical direction, the pressing part 51 is exposed to the handle part 10 to facilitate the operator to trigger; the locking part 52 is a hollow structure, the unlocking channel 521 longitudinally penetrates the locking part 52, the side through holes 522 are arranged on the opposite two side walls of the locking part 52, the unlocking element 50 further has a deformation arm 523, one deformation arm 523 is arranged in each side through hole 522, the outer side of the deformation arm 523 has a first clamping block 5231, the side wall close to the locking part 52 of the limiting plate 17 is provided with two limiting clamping grooves in the vertical direction, which are matched with the first clamping block 5231; when the unlocking element 50 is in the locked state, the unlocking channel 521 is dislocated with the limiting hole 171, and the first clamping block 5231 is clamped into the first limiting clamping groove; pressing the unlocking element 50 to move it towards the handle part 10, the first clamping block 5231 is clamped into the second limiting clamping groove; at this time, the unlocking element 50 is unlocked, the unlocking channel 521 is coaxial with the limiting hole 171, and the limiting part 423 can move along the longitudinal direction of the handle part 10.

[0060] In this embodiment, the locking part 52 of the unlocking element 50 has four side walls, and the side through holes 522 on the locking part 52 are arranged on the same two side walls as the unlocking channel 521. The other structural components of this embodiment will not be described again, please refer to the first embodiment of the delivery device.

[0061] Delivery device 100 embodiment three An important difference between this embodiment and the above-mentioned delivery device 100 embodiments one and two is that the push button 41 drives the guide sheath 21 to move in the same direction in this embodiment.

[0062] Please refer to FIGS. 4A-4E , the delivery device 100 includes a housing, a sheath assembly 20, an ejector 30, and a push assembly 40, wherein the housing forms the handle part 10 of the delivery device 100 to facilitate the operator to hold; the sheath assembly 20 is detachably arranged at the head end of the handle part 10; the sheath assembly 20 has a guide sheath 21 capable of storing a suprachoroidal space implant; the ejector 30 is fixed inside the handle part 10 along the longitudinal direction of the handle part 10, and at least part of the ejector 30 is arranged in the guide sheath 21, capable of acting on the suprachoroidal space implant; the push assembly 40 is at least partially exposed to the handle part 10, capable of acting on the sheath assembly 20, guiding the guide sheath 21 to move along the longitudinal direction of the handle part 10, so that the ejector 30 can push the suprachoroidal space implant out of the guide sheath 21 and implant it into the suprachoroidal space.

[0063] In this embodiment, the sheath assembly 20 is separated from the handle part 10 in the non-use state, and the sheath assembly 20 is installed on the handle part 10 in the use state. In order to realize the detachable connection of the sheath assembly 20 and the push assembly 40, the sheath assembly 20 further includes a head end connector 22, such asFIG. 4A As shown, the head end connector 22 is in a whole cylindrical structure, the head of the head end connector 22 is fixedly connected with the guide sheath 21, and the tail of the head end connector 22 is detachably connected with the pushing assembly 40; and the outer contour size of the head of the head end connector 22 is larger than that of the tail, so that the head of the head end connector 22 can be stopped in the handle part 10. The structure of the guide sheath 21 in the embodiment is the same as that of the above-mentioned delivery device 100 in the first and second embodiments, and will not be described here.

[0064] In addition, the suprachoroidal implant and the sheath assembly 20 in the embodiment are also stored separately before use; the suprachoroidal implant system further comprises a packaging body (not shown), the packaging body comprises a liquid storage container and a sealing member, the liquid storage container stores a holding liquid, the suprachoroidal implant is installed in the guide sheath 21 before use, and the sheath assembly is stored in the holding liquid; the sealing member seals the liquid storage container to prevent the holding liquid from leaking; when the suprachoroidal implant and the sheath assembly are used, the sealing member is opened, the handle part is connected with the sheath assembly, and then the sheath assembly is taken out from the holding liquid.

[0065] Further, as shown in FIG. 4E Since the handle part 10 is separated from the sheath assembly 20 before use, the ejector 30 is exposed to the handle part 10, in order to achieve protection of the ejector 30, the suprachoroidal implant system further comprises a protective cap 70; the protective cap 70 is detachably connected with the handle part, can be covered around the part of the ejector 30 exposed to the handle part 10, and achieves protection of the ejector 30; the protective cap 70 is removed when the handle part 10 is used.

[0066] Further, as shown in FIG. 4C The pushing assembly 40 at least comprises a pushing button 41 and a sheath transmission element 42, wherein the pushing button 41 is at least partially exposed to the handle part 10, so that the operator can operate the pushing button 41; the sheath transmission element 42 is slidingly arranged in the handle part 10, one end of the sheath transmission element 42 is detachably connected with the sheath assembly 20, and the sheath transmission element 42 can be driven by the pushing button 41 to guide the guide sheath 21 to move along the longitudinal direction of the handle part 10.

[0067] Specifically, the pushing button 41 comprises a pushing part 411, a connecting part 412 and a driving part 413, wherein the pushing part 411 is exposed to the handle part 10, the pushing part 411 is detachably connected with the connecting part 412, for example, snap connection; the connecting part 412 and the driving part 413 are integrally formed, the driving part 413 is in a plate structure, and a first protrusion 414 is arranged on the top of the driving part 413 along the longitudinal direction; as FIG. 4DAs shown, the inner wall of the handle portion 10 is provided with a second protrusion 103 matched with the first protrusion 414 along the longitudinal direction, and the first protrusion 414 and the second protrusion 103 form a line contact, thereby reducing the resistance of the driving portion 413 to move.

[0068] Further, the sheath transmission element 42 includes a delivery portion 421, a transmission portion 422 and a limiting portion 423 in the longitudinal direction; the delivery portion 421 is detachably connected with the tail portion of the head end connector 22; the transmission portion 422 is in a plate structure, and an insertion portion 4226 is arranged on the top of the transmission portion 422; the insertion portion 4226 can be inserted into and fixed in the connecting portion 412 in the push button 41, so that the push button 41 can drive the sheath transmission element 42 to move in the same direction.

[0069] In the embodiment, the top of the handle portion 10 is provided with a button sliding groove 104 matched with the push button 41 along the longitudinal direction, so that the push button 41 can move longitudinally in the button sliding groove 104.

[0070] In order to prevent the operator from misoperation, the conveyor 100 also has a mistaken touch prevention function; specifically, as shown in FIG. 4C As shown, the conveyor 100 also includes an unlocking element 50, which acts on the push assembly 40; when the unlocking element 50 is in a locked state, it limits the movement of the push assembly 40 along the longitudinal direction of the handle portion 10; when the unlocking element 50 is in an unlocked state, it allows the push assembly 40 to move along the longitudinal direction of the handle portion 10. In the embodiment, the unlocking element 50 is in a plate structure and can at least partially enclose the button sliding groove 104 to limit the movement of the push button 41; after the unlocking element 50 is removed, the push button 41 can slide longitudinally.

[0071] In addition, in the embodiment, the push button 41 in the push assembly 40 is at the front side of the handle portion 10 in the initial state and cannot move to the front side of the handle portion 10 due to the limitation of the shell; at the same time, the push button 41 cannot move to the rear side of the handle portion 10 due to the limitation of the unlocking element 50 on the movement of the limiting portion 423, that is, the push button 41 is limited and cannot move in the front-rear direction of the handle portion 10; when the unlocking element 50 is in the unlocked state, the push button 41 can only move to the rear side of the handle portion 10, thereby driving the limiting portion 423 to move rearward.

[0072] Further, in the embodiment, the shell includes a first shell portion 11 and a second shell portion 12 which are symmetrical to each other and can be detachably connected, thereby facilitating the assembly of the entire conveyor 100. The inner wall of the second shell portion 12 is provided with a protruding ejection piece fixing block 80 for fixing the ejection piece 30.

[0073] Further, as shown in FIG. 5 The process of implanting the suprachoroidal implant by the delivery device of each embodiment described above into the suprachoroidal space a300 is as follows: Step 1: Make a surgical incision at the limbus a500; Step 2: Inject a certain amount of viscoelastic agent into the anterior chamber to dilate the angle; Step 3: Extend the delivery device loaded with the implant from the surgical incision, and the head end of the delivery device is inserted into the suprachoroidal space a300; Step 4: Manipulate the handle of the delivery device to release the implant; Step 5: Withdraw the delivery device and extract the viscoelastic agent; Step 6: Suture the surgical incision at the limbus a500.

[0074] Finally, it should be noted that if the present application has any directional indications (such as up, down, left, right, front, back, etc.), the directional indications are only used to explain the relative positional relationship, movement condition, etc. between components in a certain specific posture (as shown in the drawings), and if the specific posture changes, the directional indications will also change accordingly.

[0075] In addition, if the present application has any description of "first", "second", etc., the description of "first", "second", etc. is only for description purposes, and cannot be understood as indicating or implying the relative importance of the indicated technical features or implicitly indicating the number of indicated technical features. Therefore, the features limited by "first", "second" can explicitly or implicitly include at least one of the features. In addition, the technical solutions of each embodiment can be combined with each other, but it must be based on the realization of ordinary skilled in the art, when the combination of technical solutions appears contradictory or unachievable, it should be considered that the combination of technical solutions does not exist, nor within the scope of protection claimed by the present application.

[0076] The above is only an embodiment of the present application, and does not limit the patent scope of the present application, any equivalent structure or equivalent process transformation using the contents of the present application specification and drawings, or direct or indirect application in other related technical fields, are also included in the patent protection scope of the present application.

Claims

1. A suprachoroidal implant system, characterized in that, include: A suprachoroidal implant, the suprachoroidal implant having a porous structure, is used for implantation into the suprachoroidal cavity to drain aqueous humor from the suprachoroidal space between the choroid and the sclera to reduce intraocular pressure; The suprachoroidal implant includes an implant body, which includes a proximal end, a distal end, and a middle part in the longitudinal direction. The proximal end is the end of the implant that is close to the anterior chamber after it is implanted into the eye. The lower surface of the implant body is flat, and the upper surface of the implant body is at least partially arcuate. The thickness of the implant body gradually increases from the distal end to the middle part. A delivery device for implanting the suprachoroidal implant into the suprachoroidal space, wherein the delivery device comprises: A housing that forms the handle portion of the conveyor; A sheath assembly is detachably disposed at the head end of the handle portion; the sheath assembly has a guide sheath capable of storing the suprachoroidal implant; An ejector is fixed inside the handle portion along its longitudinal direction; the ejector is at least partially inserted into the guide sheath and can act on the suprachoroidal implant. A push component, at least partially exposed in the handle portion, is capable of acting on the sheath assembly to guide the guide sheath to move longitudinally along the handle portion, so that the ejector can push the suprachoroidal implant out of the guide sheath and implant it into the suprachoroidal cavity.

2. The suprachoroidal implant system according to claim 1, characterized in that, The length of the implant body is 4-8 mm, and the width of the implant body in the lateral direction is 0.8-1.8 mm; Preferably, the maximum thickness of the implant body from the upper surface to the lower surface is 0.4~1.2mm, and the minimum thickness of the implant body from the upper surface to the lower surface is 0.2~0.6mm.

3. The suprachoroidal implant system according to claim 1, characterized in that, The porous structure has a pore size of 10~60μm and a porosity of 30~70%; Preferably, the surface of the proximal end has a display mark adjacent to the proximal end face of the proximal end, and the length of the proximal end for implantation into the anterior chamber is 0~0.5mm.

4. The suprachoroidal implant system according to claim 1, characterized in that, The sheath assembly also includes a head end connector, which is detachably connected to the push assembly; The first end of the guide sheath is fixedly connected to the head end connector, and the second end of the guide sheath extends away from the handle portion.

5. The suprachoroidal implant system according to claim 4, characterized in that, The head end connector includes: A head-end connector is detachably connected to the handle portion. The head-end connector has a cylindrical structure and a through hole on the side away from the handle portion for the guide sheath to pass through. A sheath fixing member is disposed within the head end connector and stops at the through hole. One end of the sheath fixing member is fixedly connected to the first end of the guide sheath, and the other end of the sheath fixing member is detachably connected to the push assembly. Under the drive of the push assembly, the sheath fixing member guides the guide sheath to move along the longitudinal direction of the handle portion.

6. The suprachoroidal implant system according to any one of claims 1 to 5, characterized in that, The push component includes: A push button is at least partially exposed on the handle portion; A sheath drive element is slidably disposed within the handle portion. One end of the sheath drive element is detachably connected to the sheath assembly and can be driven by the push button to guide the guide sheath to move along the longitudinal direction of the handle portion.

7. The suprachoroidal implant system according to claim 6, characterized in that, The push assembly also includes a rotating gear, which is connected between the push button and the sheath drive element.

8. The suprachoroidal implant system according to claim 6, characterized in that, The conveyor further includes an unlocking element that acts on the push assembly. When the unlocking element is in a locked state, it restricts the push assembly from moving along the longitudinal direction of the handle portion. When the unlocking element is in an unlocked state, it allows the push assembly to move along the longitudinal direction of the handle portion.

9. The suprachoroidal implant system according to claim 1, characterized in that, The suprachoroidal implant system also includes an encapsulation body, which includes a liquid reservoir and a seal. The liquid reservoir contains a holding fluid, and the seal can close the liquid reservoir. Before use, the suprachoroidal implant is installed in the guide sheath and stored in the retention fluid along with the sheath assembly. When the suprachoroidal implant is used, the seal is opened, the handle is connected to the sheath assembly, and the sheath assembly is withdrawn from the storage container.

10. The suprachoroidal implant system according to claim 9, characterized in that, The suprachoroidal implant system also includes a protective cap; Before use, the handle portion is separated from the sheath assembly, such that the protective cap is located around the portion of the ejector protruding part that is exposed on the handle portion and is connected to the handle portion. When the conveyor is in use, the protective cap is removed, and the handle is connected to the sheath assembly.

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