Automatic filling production line for in-vitro detection reagent

By designing an automated filling production line for in vitro diagnostic reagents, the automated filling, weighing, sealing, and leakage testing of reagent bottles were achieved, solving the problems of unstable filling and low efficiency, improving production efficiency and accuracy, reducing human error, and enhancing user experience.

CN121341518APending Publication Date: 2026-01-16RULAMATE AUTOMATIC TECHN SUZHOU
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Patent Information

Application Number
CN202511531194.2
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-10-24
Publication Date
2026-01-16

AI Technical Summary

Technical Problem

In the existing technology, the filling process of in vitro diagnostic reagents suffers from problems such as unstable filling volume and low production efficiency due to manual operation.

Method used

An automated filling production line for in vitro diagnostic reagents was designed, including a reagent bottle feeding and sorting module, a feeding module, a laser marking and barcode scanning module, an automated filling and weighing module, an automated film feeding and heat-sealing module, an automated film cutting and waste film collection module, a leak testing mechanism, and a reagent bottle conveying line, realizing the automation of feeding, filling, weighing, sealing, and leak testing.

Benefits of technology

It improves filling efficiency and accuracy, reduces human error, saves costs and time, and enhances the user experience.

✦ Generated by Eureka AI based on patent content.

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Patent Text Reader

Abstract

The invention provides an automatic filling production line for an in-vitro detection reagent, which realizes automation of feeding, filling, weighing, film sealing and leakage testing, not only improves the filling efficiency and precision and reduces personal errors, but also saves the cost and time and improves the user experience. The system comprises a reagent bottle feeding and sorting module which comprises a reagent bottle feeding mechanism and a reagent bottle sorting structure; a reagent bottle feeding module; a laser marking and code scanning module; an automatic filling and weighing module; automatic film supply and heat sealing of the film group are realized; an automatic film cutting and waste film collecting module; a leakage test mechanism; a reagent bottle conveying line; and an automatic discharging and transferring module. The reagent bottle conveying line is respectively provided with a plurality of reagent bottle placing racks which are arranged at equal intervals along the length direction of a line body, each reagent bottle is clamped and supported by two side arms of the reagent bottle placing racks from top to bottom, and the reagent bottle conveying line comprises an upper conveying line and a lower return line.
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Description

Technical Field

[0001] This invention relates to the technical field of filling operations, specifically to an automated filling production line for in vitro diagnostic reagents. Background Technology

[0002] In vitro diagnostic reagents need to be filled into containers such as Figure 1 The reagent bottle 1 shown has a reagent placement area 1-1 on its cavity. Reagents need to be filled into the reagent placement area 1-1. After the reagents are filled, the entire upper surface of the cavity of the reagent bottle 1 needs to be sealed with a film 2. In the existing technology, manual filling is generally used when filling the reagent placement area 1-1. Manual operation results in poor stability of the filling volume and relatively low production efficiency. In order to improve the filling stability, there is an urgent need to design an automatic filling production line for reagent bottles. Summary of the Invention

[0003] To address the aforementioned issues, this invention provides an automated filling production line for in vitro diagnostic reagents, which automates the processes of feeding, filling, weighing, sealing, and leakage testing. This not only improves filling efficiency and accuracy and reduces human error but also saves costs and time, enhancing the user experience.

[0004] An automated filling production line for in vitro diagnostic reagents, characterized in that it comprises: A reagent bottle feeding and sorting module, which includes a reagent bottle feeding mechanism and a reagent bottle sorting structure; Reagent bottle feeding module; Laser marking and barcode scanning modules; Automatic filling and weighing module; Automatic film feeding and heat-sealing film assembly; Automatic film cutting and waste film collection module; Leakage testing organization; Reagent bottle conveyor line; And automatic material unloading and transfer modules; The reagent bottle conveying line is equipped with several reagent bottle placement racks arranged at equal intervals along the length of the line. Each reagent bottle is held and supported by the two arms of the reagent bottle placement rack from top to bottom. The reagent bottle conveying line includes an upper conveying line and a lower return line. The upper conveying line is sequentially equipped with a reagent bottle loading station, a reagent bottle marking and scanning station, a reagent bottle filling station, a reagent bottle weighing station, an automatic film supply and heat sealing station, a film cutting station, and a leak testing station along its length. The reagent bottle feeding sequencing module sequentially arranges and conveys the reagent bottles to the discharge port, the transfer robot of the reagent bottle feeding module transfers the reagent bottles from the discharge port to the reagent bottle feeding station of the upper conveying line and supports and places the reagent bottles on the reagent bottle placing rack, the reagent bottle conveying line drives the upper conveying line to sequentially pass the reagent bottle marking and scanning station, the reagent bottle filling station, the reagent bottle weighing station, the automatic film supplying and heat sealing station, the film cutting station and the leakage testing station, and the lower transfer module transfers the reagent bottles tested by the leakage testing mechanism to the finished product packaging area at the rear.

[0005] It is further characterized in that: The reagent bottle conveying line is provided with circulating rotating line bodies on both sides in the width direction, and the reagent bottle conveying line simultaneously drives two groups of reagent bottles to parallel forward operation, which improves the operation efficiency of the whole production line. The reagent bottle marking and scanning station, the reagent bottle filling station, the reagent bottle weighing station, the automatic film supplying and heat sealing station, the film cutting station and the leakage testing station of each group of upper conveying lines are respectively provided with corresponding modules or mechanisms. The working surface domain of the transfer robot of the reagent bottle feeding module covers the discharge port and the reagent bottle feeding stations of the upper conveying lines on both sides. The laser marking mechanism and the code scanning mechanism are respectively arranged on the laser marking and code scanning module on each side, the laser marking mechanism marks on the reagent bottle, and the code scanning mechanism scans and retains the two-dimensional code of the corresponding reagent bottle to form a work log. The automatic filling and weighing module includes an automatic filling mechanism located above the upper conveying line and a weighing mechanism located between the upper conveying line and the lower return line, the automatic filling mechanism includes a tank at the top and filling discharge mechanisms on both sides, and each side of the filling discharge mechanism is respectively arranged corresponding to the weighing mechanism. The automatic filling and weighing module covers at least two reagent bottle placing racks, after all the reagent bottle placing racks covered by the automatic filling and weighing module are evenly filled with unfilled reagent bottles, the tank synchronously fills the reagent bottles in the actual placing area through the filling discharge mechanisms on both sides to a set weight, then the reagent bottles are lifted by the weighing mechanism driven by the synchronous lifting mechanism, so that the reagent bottles are separated from the arms on both sides of the reagent bottle placing rack, the reagent bottles are completely supported on each independent weighing mechanism, and the online weighing operation is completed. When the glue filling weight in the corresponding reagent bottle is small, the corresponding filling discharge mechanism is driven to supplement the reagent to the reagent bottle until the reagent amount of all reagent bottles is qualified, since the filling discharge mechanism only has partial blockage, the reagent weight is generally not overweight, if the reagent weight is found to be overweight, the corresponding filling discharge mechanism needs to be repaired or the whole automatic filling mechanism needs to be repaired or debugged. The automatic film supplying and heat sealing film group on each side comprises a film supplying mechanism, a film feeding mechanism, a film cutting mechanism and a heat sealing film mechanism, the film feeding mechanism drives the film to cover the upper surface of the reagent bottle from outside to inside, then the film cutting mechanism cuts the film, and then the heat sealing film mechanism completes the heat sealing operation towards the film; The automatic film cutting and waste film collecting module on each side comprises an automatic film cutting mechanism and a waste film collecting mechanism, the automatic film cutting mechanism cuts the peripheral film on the upper surface of the reagent bottle according to a set shape after the heat sealing is completed, the waste film collecting mechanism comprises a waste film collecting guide cavity, a waste film collecting vacuum generator and a waste film collecting barrel, the clamping jaws of the inlet of the waste film collecting guide cavity clamp the waste film which is extended outwardly and expanded outwardly relative to the reagent bottle, then the waste film collecting vacuum generator adsorbs the waste material cut by the automatic film cutting mechanism, and the waste material falls into the waste film collecting barrel along the waste film collecting guide cavity; The leakage testing mechanism on each side comprises a vertical seat body, the vertical seat body comprises a bottom plate, a middle plate and a top plate, a servo rotating mechanism is arranged on the middle plate, the two ends of the rotating arm of the servo rotating mechanism are respectively provided with clamping air claws, a profiling clamp is further arranged on the upper part of the middle plate and corresponds to the position of the testing station, the profiling clamp is provided with a vacuum box body, the bottom of the vacuum box body is connected with a vacuum pumping module, the bottom of the profiling clamp is provided with a lifting air cylinder, and the top of the vacuum box body is further provided with a displacement sensor, the displacement sensor is arranged corresponding to each independent cavity of the reagent bottle, in the leakage testing state, the clamping air claws place the reagent bottle in the vacuum box body, the clamping air claws are loosened and separated from the upper surface area of the reagent bottle, then the vacuum box body is pumped, then the lifting air cylinder pushes the profiling clamp to rise until each displacement sensor corresponds to the upper film of each independent cavity of the reagent bottle, and each displacement sensor respectively detects whether the cavity of the testing bottle is bulged, so as to judge whether there is leakage.

[0006] After the scheme of the application is adopted, the reagent bottle feeding and sequencing module sequentially arranges and conveys the reagent bottles to the discharge port, the transfer robot of the reagent bottle loading module transfers the reagent bottles from the discharge port to the reagent bottle loading station of the upper conveying line, supports and places the reagent bottles on the reagent bottle placing rack, the reagent bottle conveying line drives the upper conveying line to sequentially convey the reagent bottles through the reagent bottle marking and scanning station to perform marking and scanning, the reagent bottle filling station to perform reagent filling, the reagent bottle weighing station to perform reagent weighing, the automatic film supplying and heat sealing station to perform film heat sealing, the film cutting station to cut and remove the waste film and the leakage testing station to perform sealing test on the reagent bottle, and then the unloading transfer module transfers the reagent bottles tested by the leakage testing mechanism to the finished product packaging area at the rear, which realizes the automation of loading, filling, weighing, film sealing and leakage testing, improves the filling efficiency and precision, reduces human error, saves cost and time and improves user experience. BRIEF DESCRIPTION OF DRAWINGS

[0007] Figure 1A perspective view of the reagent bottle corresponding to the present application; Figure 2 A perspective view of the structure of the present application; Figure 3 A top view of the structure of the present application; Figure 4 A perspective view of the reagent bottle conveying line corresponding to the present application; Figure 5 A perspective view of the weighing module of the present application; Figure 6 A perspective view of the automatic film cutting and waste film collecting module of the present application; Figure 7 A perspective view of the leakage testing mechanism of the present application; The names corresponding to the serial numbers in the figure are as follows: Reagent bottle 1, reagent placement area 1-1; Reagent bottle feeding and sorting module 10, reagent bottle feeding mechanism 11, reagent bottle sorting structure 12, discharge port 13, reagent bottle feeding module 20, transfer robot 21, laser marking and code scanning module 30, laser marking mechanism 31, code scanning mechanism 32, automatic filling and weighing module 40, automatic filling mechanism 41, tank 411, filling and discharging mechanism 412, weighing mechanism 42, synchronous lifting mechanism 421, support frame 422, high-precision electronic scale 423, automatic film supply and heat sealing film group 50, film supply mechanism 51, film feeding mechanism 52, heat sealing film mechanism 53, automatic film cutting and waste film collecting module 60, automatic film cutting mechanism 61, waste film collecting mechanism 62, waste film collecting guide cavity 621, waste film collecting vacuum generator 622, waste film collecting barrel 623, leakage testing mechanism 70, vertical seat body 71, servo rotation mechanism 72, rotary arm 73, clamping air claw 74, profiling clamp 75, vacuum box body 76, vacuum pumping module 77, lifting cylinder 78, displacement sensor 79, reagent bottle conveying line 80, upper conveying line 81, reagent bottle feeding station 811, reagent bottle marking and scanning station 812, reagent bottle filling station 813, reagent bottle weighing station 814, automatic film supply and heat sealing station 815, film cutting station 816, leakage testing station 817, lower return line 82, automatic unloading and transfer module 90, reagent bottle placement rack 100, side arm 101. DETAILED DESCRIPTION

[0008] The in vitro detection reagent automatic filling production line, see Figures 2-7 , comprising a reagent bottle feeding and sorting module 10, a reagent bottle feeding module 20, a laser marking and code scanning module 30, an automatic filling and weighing module 40, an automatic film supply and heat sealing film group 50, an automatic film cutting and waste film collecting module 60, a leakage testing mechanism 70, a reagent bottle conveying line 80, and an automatic unloading and transfer module 90; The reagent bottle feeding and sequencing module 10 comprises a reagent bottle feeding mechanism 11 and a reagent bottle sequencing structure 12. The reagent bottle conveying line 80 is provided with a plurality of reagent bottle placing racks 100 arranged at equal intervals along the length direction of the line body. Each reagent bottle 1 is clamped and supported by the two side arms 101 of the reagent bottle placing rack 100 from top to bottom. The clamping space of the two side arms 101 is a converging structure from top to bottom, and the bottom is open. The reagent bottle conveying line 80 comprises an upper conveying line 81 and a lower return line 82. The upper conveying line 81 is sequentially provided with a reagent bottle feeding station 811, a reagent bottle marking and scanning station 812, a reagent bottle filling station 813, a reagent bottle weighing station 814, an automatic film feeding and heat sealing station 815, a film cutting station 816, and a leakage testing station 817 along the length direction. The reagent bottle feeding and sequencing module 10 sequentially arranges and conveys the reagent bottles 1 to the discharge port 13. The transfer robot 21 of the reagent bottle feeding module 20 transfers the reagent bottles 1 from the discharge port 13 to the reagent bottle feeding station 811 of the upper conveying line 81 and supports and places the reagent bottles 1 on the reagent bottle placing racks 100. The reagent bottle conveying line 80 drives the upper conveying line 81 to sequentially pass the reagent bottle marking and scanning station 812, the reagent bottle filling station 813, the reagent bottle weighing station 814, the automatic film feeding and heat sealing station 815, the film cutting station 816, and the leakage testing station 817. The discharging and transferring module 90 transfers the reagent bottles 1 tested by the leakage testing mechanism 70 to the finished product packaging area at the rear.

[0009] In specific implementation, the reagent bottle filling station 813 and the reagent bottle weighing station 814 are the same station, and the reagent bottle weighing station performs online weighing operation.

[0010] In specific embodiments, two line bodies rotating circularly are respectively arranged on the width direction sides of the reagent bottle conveying line 80. The reagent bottle conveying line 80 simultaneously drives two groups of reagent bottles to perform parallel forward movement, which improves the operation efficiency of the whole production line. Corresponding modules or mechanisms are respectively arranged outside the reagent bottle marking and scanning station 812, the reagent bottle filling station 813, the reagent bottle weighing station 814, the automatic film feeding and heat sealing station 815, the film cutting station 816, and the leakage testing station 817 of each group of upper conveying lines 81. The working surface domain of the transfer robot 21 of the reagent bottle feeding module 20 covers the discharge port 13 and the reagent bottle feeding stations 811 of the upper conveying lines 81 respectively located on the two sides. The upper conveying lines 81 perform step-by-step conveying, so that the transfer robot 21 can complete the transfer operation of two reagent bottles 1 in the gap. A laser marking mechanism 31 and a code scanning mechanism 32 are respectively arranged on each side of the laser marking and code scanning module 30. The laser marking mechanism 31 marks on the reagent bottle 1, and the code scanning mechanism 32 scans and retains the two-dimensional code of the corresponding reagent bottle 1 to form a work log. The automatic filling and weighing module 40 includes an automatic filling mechanism 41 located above the upper conveying line, and a weighing mechanism 42 located between the upper conveying line 81 and the lower return line 82, respectively, the automatic filling mechanism 41 includes a top tank 411 and two filling and discharging mechanisms 412 on both sides, each filling and discharging mechanism 412 on both sides is arranged corresponding to the weighing mechanism 42; The automatic filling and weighing module 40 covers six reagent bottle placing racks 100, when the six reagent bottle placing racks 100 covered by the automatic filling and weighing module 40 are filled with un-filled reagent bottles 1, the tank 411 synchronously fills the reagent bottles 1 in the actual placement area with the set weight of reagent through the filling and discharging mechanisms 412 on both sides, then the reagent bottles 1 are lifted by the weighing mechanism 42 driven by the synchronous lifting mechanism 421, so that the reagent bottles 1 are separated from the two side arms 101 of the reagent bottle placing rack 100 and completely supported on the support frame 422 of each independent weighing mechanism 42, the support frame 422 is supported on the independent high-precision electronic scale 423, thereby completing the online weighing operation; When the corresponding reagent bottle 1 has a small amount of glue inside, the corresponding filling and discharging mechanism 412 is driven to supplement the reagent to the reagent bottle 1 until the reagent amount of all reagent bottles 1 is qualified, since the filling and discharging mechanism 412 only has partial blockage, generally, the reagent weight will not be overweight, if the reagent weight is found to be overweight, the machine needs to be stopped, and the corresponding filling and discharging mechanism 412 needs to be repaired or the entire automatic filling mechanism 41 needs to be repaired or adjusted; Each automatic film supplying and heat sealing film group 50 on both sides includes a film supplying mechanism 51, a film feeding mechanism 52, a film cutting mechanism (hidden in the figure), and a heat sealing film mechanism 53, the film feeding mechanism 52 drives the film to cover the upper surface of the entire reagent bottle 1 from outside to inside, then the film cutting mechanism cuts the film, and then the heat sealing film mechanism 53 completes the heat sealing operation towards the film; Each automatic film cutting and waste film collecting module 60 on both sides includes an automatic film cutting mechanism 61 and a waste film collecting mechanism 62, the automatic film cutting mechanism 61 cuts the peripheral film on the upper surface of the reagent bottle 1 according to the set shape after heat sealing, the waste film collecting mechanism 62 includes a waste film collecting guide cavity 621, a waste film collecting vacuum generator 622, and a waste film collecting barrel 623, the clamping jaws of the inlet of the waste film guide cavity 621 clamps the waste film which is extended and expanded outside relative to the reagent bottle 1, then the waste film collecting vacuum generator 622 adsorbs the waste film cut by the automatic film cutting mechanism 61, and the waste film falls into the waste film collecting barrel 623 along the waste film guide cavity 621; The leakage test mechanism 70 on each side comprises a vertical seat body 71 comprising a bottom plate, a middle plate and a top plate, the middle plate is provided with a servo rotating mechanism 72, both ends of the rotating arm 73 of the servo rotating mechanism 72 are respectively provided with clamping air claws 74, and the upper part of the middle plate is further provided with a profiling clamp 75 corresponding to the position of the test station, the profiling clamp 75 is provided with a vacuum box body 76, the bottom of the vacuum box body 76 is connected with a vacuum pumping module 77, the bottom of the profiling clamp 75 is provided with a lifting air cylinder 78, and the top of the vacuum box body 76 is further provided with a displacement sensor 79, the displacement sensor 79 is arranged corresponding to each independent cavity of the reagent bottle 1, in the leakage test state, the clamping air claws 74 place the reagent bottle 1 in the vacuum box body 76, the clamping air claws 74 are loosened and separated from the upper surface area of the reagent bottle 1, then the vacuum box body 76 is pumped, then the lifting air cylinder 78 pushes the profiling clamp 75 to rise until each displacement sensor 79 corresponds to the upper film of each independent cavity of the reagent bottle 1, and each displacement sensor 79 detects whether the cavity of the test bottle is bulged, so as to judge whether it is leaked.

[0011] The reagent bottle feeding and sequencing module 10 sequentially arranges and conveys the reagent bottles 1 to the discharge port 13, the transfer robot 21 of the reagent bottle loading module 20 transfers the reagent bottles 1 from the discharge port 13 to the reagent bottle loading station 211 of the upper conveying line 21 and supports and places the reagent bottles 1 on the reagent bottle placing rack 100, the reagent bottle conveying line 80 drives the upper conveying line 81 to sequentially convey the reagent bottles 1 through the reagent bottle marking and scanning station 812 to perform marking and scanning, the reagent bottle filling station 813 to perform reagent filling, the reagent bottle weighing station 814 to perform reagent weighing, the automatic mold feeding and heat sealing station 815 to perform film heat sealing, the film cutting station 816 to perform waste film cutting and waste discharge, and the leakage test station 817 to perform reagent bottle sealing test, and then the unloading and transfer module 90 transfers the reagent bottles tested by the leakage test mechanism to the finished product packaging area at the rear, which realizes the automation of loading, filling, weighing, film sealing and leakage test, improves the filling efficiency and precision, reduces human error, saves cost and time, and improves user experience.

[0012] It is apparent to those skilled in the art that the present application is not limited to the details of the foregoing exemplary embodiments, and the present application can be implemented in other specific forms without departing from the spirit or essential characteristics of the present application. Therefore, the embodiments should be considered in all respects as illustrative and not restrictive, and the scope of the present application is defined by the appended claims rather than the foregoing description, and it is intended to encompass all changes falling within the meaning and scope of the equivalent elements of the claims. Any reference signs in the claims should not be considered as limiting the claims involved.

[0013] Furthermore, it should be understood that although the specification is described in terms of embodiments, not every embodiment includes every feature described. The specification can include implicit combinations of explicitly mentioned features and / or explicit combinations of implicitely mentioned features. Each embodiment depends on the explicit combinations of features and / or the implicit combinations of features made specifically within that embodiment, and each such embodiment can be combined with every other such embodiment to create further embodiments.

Claims

1. An automatic filling production line for in vitro diagnostic reagents, characterized in that, It comprises: a reagent bottle feeding and sequencing module comprising a reagent bottle feeding mechanism and a reagent bottle sequencing structure; a reagent bottle feeding module; a laser marking and code scanning module; an automatic filling and weighing module; an automatic film feeding and heat sealing module; an automatic film cutting and waste film collecting module; a leakage testing mechanism; a reagent bottle conveying line; and an automatic unloading and transferring module; The reagent bottle conveying line is respectively provided with a plurality of reagent bottle placing racks arranged at equal intervals along the length direction of the line body. Each reagent bottle is clamped and supported by the two side arms of the reagent bottle placing rack from top to bottom. The reagent bottle conveying line comprises an upper conveying line and a lower return line. The upper conveying line is sequentially provided with a reagent bottle feeding station, a reagent bottle marking and scanning station, a reagent bottle filling station, a reagent bottle weighing station, an automatic film feeding and heat sealing station, a film cutting station, and a leakage testing station along the length direction. The reagent bottle feeding and sequencing module sequentially arranges and conveys the reagent bottles to the discharge port. The transfer robot of the reagent bottle feeding module transfers the reagent bottles from the discharge port to the reagent bottle feeding station of the upper conveying line and supports and places the reagent bottles on the reagent bottle placing racks. The reagent bottle conveying line drives the upper conveying line to sequentially pass the reagent bottle marking and scanning station, the reagent bottle filling station, the reagent bottle weighing station, the automatic film feeding and heat sealing station, the film cutting station, and the leakage testing station. The unloading and transferring module transfers the reagent bottles tested by the leakage testing mechanism to the finished product packaging area at the rear.

2. The in-vitro diagnostic reagent automatic filling production line according to claim 1, characterized in that: The two sides of the width direction of the reagent bottle conveying line are respectively provided with circulating rotating line bodies. The reagent bottle conveying line simultaneously drives the two groups of reagent bottles to parallelly advance.

3. The in-vitro diagnostic reagent automatic filling production line according to claim 2, characterized in that: The outside of the reagent bottle marking and scanning station, the reagent bottle filling station, the reagent bottle weighing station, the automatic film feeding and heat sealing station, the film cutting station, and the leakage testing station of each group of upper conveying lines is respectively provided with a corresponding module or mechanism.

4. The in-vitro diagnostic reagent automatic filling production line according to claim 2, characterized in that: The working surface domain of the transfer robot of the reagent bottle feeding module covers the discharge port and the reagent bottle feeding stations of the upper conveying lines on both sides.

5. The in-vitro diagnostic reagent automatic filling production line according to claim 2, characterized in that: The laser marking mechanism and the code scanning mechanism are respectively arranged on the laser marking and code scanning module on each side. The laser marking mechanism marks on the reagent bottles. The code scanning mechanism scans and retains the two-dimensional code of the corresponding reagent bottles to form a work log.

6. The in-vitro diagnostic reagent automatic filling production line according to claim 2, characterized in that: The automatic filling and weighing module comprises an automatic filling mechanism located above the upper conveying line and a weighing mechanism located between the upper conveying line and the lower return line. The automatic filling mechanism comprises a top tank and two side filling and discharging mechanisms. Each side filling and discharging mechanism corresponds to the weighing mechanism.

7. The in-vitro diagnostic reagent automatic filling production line according to claim 6, characterized in that: The automatic filling and weighing module covers at least two reagent bottle placing racks. After all the reagent bottle placing racks covered by the automatic filling and weighing module are filled with un-filled reagent bottles, the tank synchronously fills the reagent bottles in the actual placement area with a set weight of reagent through the two side filling and discharging mechanisms. Then, the reagent bottles are lifted by the weighing mechanism driven by the synchronous lifting mechanism, so that the reagent bottles are separated from the two side arms of the reagent bottle placing racks and completely supported on each independent weighing mechanism, thereby completing the online weighing operation.

8. The in-vitro diagnostic reagent automatic filling production line according to claim 2, characterized in that: Each side of the automatic film supply and heat sealing film group includes a film supply mechanism, a film feeding mechanism, a film cutting mechanism, and a heat sealing film mechanism. The film feeding mechanism covers the upper surface of the reagent bottle with film from outside to inside, and then the film cutting mechanism cuts the film, and then the heat sealing film mechanism completes the heat sealing operation towards the film.

9. The in-vitro diagnostic reagent automatic filling production line according to claim 2, characterized in that: Each side of the automatic film cutting and waste film collection module includes an automatic film cutting mechanism and a waste film collection mechanism. The automatic film cutting mechanism cuts the film on the upper surface of the reagent bottle according to the set shape. The waste film collection mechanism includes a waste film collection guide cavity, a waste film collection vacuum generator, and a waste film collection barrel. The jaws of the inlet of the waste film guide cavity hold the waste film that extends outward relative to the reagent bottle. Then the waste film collection vacuum generator adsorbs the waste film cut by the automatic film cutting mechanism. The waste film falls into the waste film collection barrel along the waste film guide cavity.

10. The in-vitro diagnostic reagent automatic filling production line according to claim 2, characterized in that: Each side of the leakage test mechanism includes a vertical seat body, which includes a bottom plate, a middle plate, and a top plate. The middle plate is provided with a servo rotation mechanism. The two ends of the rotation arm of the servo rotation mechanism are respectively provided with clamping air claws. The upper part of the middle plate is also provided with a profiling clamp corresponding to the test station. The profiling clamp is provided with a vacuum box body. The bottom of the vacuum box body is connected with a vacuum pumping module. The bottom of the profiling clamp is provided with a lifting air cylinder. The top of the vacuum box body is also provided with a displacement sensor corresponding to each independent cavity of the reagent bottle. In the leakage test state, the clamping air claws place the reagent bottle in the vacuum box body. The clamping air claws are loosened and separated from the upper surface area of the reagent bottle. Then the vacuum box body is vacuumized. Then the lifting air cylinder pushes the profiling clamp to rise until each displacement sensor corresponds to the upper film of each independent cavity of the reagent bottle. Each displacement sensor detects whether the cavity of the test bottle is bulging, thereby judging whether it is leaking.