Dioscorea composition with alpha-glucosidase inhibitory activity, application and analysis and identification method thereof
By extracting the compound (Z)-6-ethoxy-9,10-dihydroxyoctadec-7-enoic acid from yam, the gastrointestinal side effects of existing α-glucosidase inhibitors have been resolved, achieving a safe and mild hypoglycemic effect and providing an effective method for yam quality control.
CN122127222APending Publication Date: 2026-06-02SERICULTURAL &AGRI FOOD RESEARCH INSTITUTE GUANGDONG ACADEMY OF AGRICULTURAL SCIENCES +1
View PDF 0 Cites 0 Cited by
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- SERICULTURAL &AGRI FOOD RESEARCH INSTITUTE GUANGDONG ACADEMY OF AGRICULTURAL SCIENCES
- Filing Date
- 2026-04-08
- Publication Date
- 2026-06-02
AI Technical Summary
Technical Problem
Existing α-glucosidase inhibitors often cause gastrointestinal adverse reactions during use, and there is room for improvement in terms of selectivity and tissue distribution. There is an urgent need to develop safer and gentler natural alternatives.
Method used
A novel compound, (Z)-6-ethoxy-9,10-dihydroxyoctadec-7-enoic acid, was extracted from yam. The compound was obtained through a multi-step extraction and purification method, and qualitative and quantitative analyses were performed using various analytical identification methods.
Benefits of technology
This compound exhibits excellent α-glucosidase inhibitory activity, reduces gastrointestinal side effects, demonstrates a good hypoglycemic effect, and provides a reliable method for quality control of yam.
✦ Generated by Eureka AI based on patent content.
Smart Images
Figure CN122127222A_ABST
Abstract
This invention discloses a yam component with α-glucosidase inhibitory activity, its application, and analytical identification methods, belonging to the field of medicinal chemistry. The yam component is (Z)-6-ethoxy-9,10-dihydroxyoctadecano-7-enoic acid, a novel compound extracted from yam, exhibiting excellent α-glucosidase inhibitory activity, thus showing promising application prospects and value in lowering blood sugar.
Need to check novelty before this filing date? Find Prior Art